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Protein Ontology report - protein PML (human)
PR:P29590 - http://purl.obolibrary.org/obo/PR_P29590
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P29590   
  PRO nameprotein PML (human) 
  Synonyms
PRO-Short-label: EXACT:hPML
Gene-based: RELATED:MYL | PML | PP8675 | RNF71 | TRIM19
Other: EXACT:E3 SUMO-protein ligase PML (human) | promyelocytic leukemia protein (human) | RING finger protein 71 (human) | RING-type E3 SUMO transferase PML (human) | tripartite motif-containing protein 19 (human)
  Definition"A transcription factor PML that is encoded in the genome of human." [PRO:CNA, UniProtKB:P29590] 
  PRO Categoryorganism-gene 
  ParentPR:000026474 transcription factor PML
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9113 PML (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P29590
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:P29590 protein PML (human)
hPML

organism-sequence


PR:P29590-1 transcription factor PML isoform 1 (human)
hPML/iso:1
Yes
organism-modification


PR:000026480 transcription factor PML isoform 1 phosphorylated 1 (human)
hPML/iso:1/Phos:1
Yes
organism-sequence


PR:P29590-10 protein PML isoform hPML-7 (human)
hPML/iso:hPML-7

organism-sequence


PR:P29590-11 protein PML isoform hPML-11 (human)
hPML/iso:hPML-11

organism-sequence


PR:P29590-12 protein PML isoform hPML-12 (human)
hPML/iso:hPML-12

organism-sequence


PR:P29590-13 protein PML isoform hPML-13 (human)
hPML/iso:hPML-13

organism-sequence


PR:P29590-14 protein PML isoform hPML-14 (human)
hPML/iso:hPML-14

organism-sequence


PR:P29590-2 transcription factor PML isoform 2 (human)
hPML/iso:2
Yes
organism-sequence


PR:P29590-3 transcription factor PML isoform 3 (human)
hPML/iso:3
Yes
organism-sequence


PR:P29590-4 transcription factor PML isoform 4 (human)
hPML/iso:4
Yes
organism-sequence


PR:P29590-5 transcription factor PML isoform 5 (human)
hPML/iso:5
Yes
organism-sequence


PR:P29590-8 protein PML isoform hPML-2 (human)
hPML/iso:hPML-2

organism-sequence


PR:P29590-9 protein PML isoform hPML-3 (human)
hPML/iso:hPML-3

organism-modification


PR:000064635 protein PML sumoylated 1 (human)
hPML/Sumo:1

organism-modification


PR:000076676 protein PML methylated 1 (human)
hPML/Me:1

organism-modification


PR:000079131 protein PML methylated 2 (human)
hPML/Me:2

organism-modification


PR:000080018 protein PML cysteinylated 1 (human)
hPML/Cyst:1

organism-modification


PR:000082789 protein PML cysteinylated 2 (human)
hPML/Cyst:2

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0002230 positive regulation of defense response to virus by hostPR:P29590-2 hPML/iso:2 PMID:16873256
PR:P29590-4 hPML/iso:4 PMID:16873257
GO:0006605 protein targetingPR:P29590-5 hPML/iso:5 PMID:15195100
PR:P29590-5 hPML/iso:5 PMID:15195100
GO:0006915 apoptotic processPR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-5 hPML/iso:5 PMID:11080164
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damagePR:P29590-5 hPML/iso:5 PMID:12402044
GO:0030308 negative regulation of cell growthPR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-5 hPML/iso:5 PMID:9448006
GO:0030578 PML body organizationPR:P29590-3 hPML/iso:3 PMID:10779416
PR:P29590-4 hPML/iso:4 PMID:8643677
GO:0032938 negative regulation of translation in response to oxidative stressPR:P29590-5 hPML/iso:5 PMID:16915281
GO:0045892 negative regulation of DNA-templated transcriptionPR:P29590-5 hPML/iso:5 PMID:9448006
GO:0045930 negative regulation of mitotic cell cyclePR:P29590-3 hPML/iso:3 PMID:9395203
GO:0050821 protein stabilizationPR:P29590-5 hPML/iso:5 PMID:12773567
GO:0051726 regulation of cell cyclePR:P29590-3 hPML/iso:3 PMID:9583681
PR:P29590-5 hPML/iso:5 PMID:12773567

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003713 transcription coactivator activityPR:P29590-5 hPML/iso:5 PMID:15626733
PR:P29590-5 hPML/iso:5 PMID:15626733
GO:0005515 protein bindingPR:P29590-1 hPML/iso:1 PMID:20832753
PR:P29590-3 hPML/iso:3 PMID:10610177
PR:P29590-3 hPML/iso:3 PMID:10610177
PR:P29590-3 hPML/iso:3 PMID:10610177
PR:P29590-3 hPML/iso:3 PMID:10610177
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-4 hPML/iso:4 PMID:10669754
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
PR:P29590-5 hPML/iso:5 PMID:11259576
GO:0008270 zinc ion bindingPR:P29590-4 hPML/iso:4 PMID:7729428
GO:0046982 protein heterodimerization activityPR:P29590-3 hPML/iso:3 PMID:7935403
GO:0050897 cobalt ion bindingPR:P29590-4 hPML/iso:4 PMID:7729428

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000026480 hPML/iso:1/Phos:1 PMID:20832753
PR:P29590-1 hPML/iso:1 PMID:16778193
PR:P29590-2 hPML/iso:2 PMID:16778193
PR:P29590-3 hPML/iso:3 PMID:9294197
GO:0005730 nucleolusPR:P29590-5 hPML/iso:5 PMID:16778193
GO:0005737 cytoplasmPR:P29590-1 hPML/iso:1 PMID:9885291
PR:P29590-1 hPML/iso:1 PMID:9885291
PR:P29590-1 hPML/iso:1 PMID:9885291
PR:P29590-1 hPML/iso:1 PMID:9885291
PR:P29590-2 hPML/iso:2 PMID:16778193
PR:P29590-3 hPML/iso:3 PMID:16778193
PR:P29590-5 hPML/iso:5 PMID:16778193
GO:0016363 nuclear matrixPR:P29590-5 hPML/iso:5 PMID:11080164
GO:0016605 PML bodyPR:P29590-4 hPML/iso:4 PMID:9885291
PR:P29590-5 hPML/iso:5 PMID:9448006
GO:0031965 nuclear membranePR:P29590-3 hPML/iso:3 PMID:16778193