PRO Term |
GO Annotation |
Evidence |
PR:000030192 hCTNNB1/iso:1/Phos:1 UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046 |
acts_upstream_of_or_within | GO:0016055 Wnt signaling pathway |
PMID:22369945 |
enables | increased GO:0003713 transcription coactivator activity relative to PR:000002862 CTNNB1/iso:1/UnMod |
PMID:22369945 |
PR:000035770 hCTNNB1/iso:1/Phos:2 UniProtKB:P35222-1, Tyr-64, MOD:00048|Tyr-142, MOD:00048|(Tyr-331, MOD:00048 or Tyr-333, MOD:00048) |
located_in | GO:0005634 nucleus |
PMID:20026641 |
PR:000035772 hCTNNB1/iso:1/Phos:3 UniProtKB:P35222-1, Ser-33/Ser-37/Ser-45, MOD:00046|Thr-41, MOD:00047 |
enables | NOT GO:0005515 protein binding with PR:Q9Y297 BTRC |
PMID:10074433 |
NOT GO:0005515 protein binding with PR:Q9UKB1 BTRCP2 |
PMID:10074433 |
PR:000035774 hCTNNB1/iso:1/Phos:4 UniProtKB:P35222-1, Ser-45, MOD:00046 |
enables | increased GO:0005515 protein binding with PR:P12830 CAM 120/80 (human) |
PMID:12051714; PMID:20419129; PMID:23606879 |
increased GO:0005515 protein binding with PR:P49841 GSK-3 beta (human) |
PMID:12051714; PMID:20419129; PMID:23606879 |
located_in | GO:0005634 nucleus |
PMID:20419129 |
PR:000036862 hCTNNB1/iso:1/Phos:5 UniProtKB:P35222-1, Ser-552/Ser-675, MOD:00046 |
enables | increased GO:0003713 transcription coactivator activity relative to PR:000036872 hCTNNB1/iso:1/UnPhos:1 |
PMID:16476742 |
increased GO:0005515 protein binding relative to PR:000036872 hCTNNB1/iso:1/UnPhos:1 |
PMID:16476742 |
PR:000037181 hCTNNB1/iso:1/Phos:6 UniProtKB:P35222-1, Ser-37, MOD:00046|Thr-41, MOD:00047 |
located_in | decreased GO:0005912 adherens junction relative to PR:000037185 hCTNNB1/iso:1/UnPhos:2 |
PMID:19667122 |
PR:000037185 hCTNNB1/iso:1/UnPhos:2 UniProtKB:P35222-1, Ser-37/Thr-41, PR:000026291 |
enables | GO:0003713 transcription coactivator activity |
PMID:20419129 |
GO:0005515 protein binding |
PMID:20419129 |
located_in | GO:0005634 nucleus |
PMID:20419129 |
PR:000037190 hCTNNB1/iso:1/Phos:7 UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 |
acts_upstream_of_or_within | decreased GO:0007155 cell adhesion relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 |
PMID:19667122 |
GO:0010631 epithelial cell migration |
PMID:21152425 |
decreased GO:0034333 adherens junction assembly relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 |
PMID:19667122 |
enables | decreased GO:0003713 transcription coactivator activity relative to PR:000037185 hCTNNB1/iso:1/UnPhos:2 |
PMID:20419129 |
NOT GO:0005515 protein binding with PR:Q9HCS4 HMG box transcription factor 3 (human) |
PMID:21152425 |
NOT GO:0005515 protein binding with PR:Q9NQB0 HMG box transcription factor 4 (human) |
PMID:21152425 |
NOT GO:0005515 protein binding with PR:Q9UJU2 hLEF1 |
PMID:21152425 |
NOT GO:0005515 protein binding with PR:Q9Y297 BTRC |
PMID:21152425 |
NOT GO:0005515 protein binding with PR:P12830 CAM 120/80 (human) |
PMID:21152425 |
NOT GO:0005515 protein binding |
PMID:21152425 |
located_in | GO:0005737 cytoplasm |
PMID:20419129 |
decreased GO:0005912 adherens junction relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 |
PMID:19667122 |
PR:000037192 hCTNNB1/iso:1/Phos:8 UniProtKB:P35222-1, Tyr-333, MOD:00048 |
acts_upstream_of_or_within | GO:0007173 epidermal growth factor receptor signaling pathway |
PMID:22056988 |
enables | GO:0003713 transcription coactivator activity |
PMID:22056988 |
GO:0005515 protein binding |
PMID:22056988 |
located_in | GO:0005634 nucleus |
PMID:22056988 |
PR:000037194 hCTNNB1/iso:1/Phos:9 UniProtKB:P35222-1, Tyr-86/Tyr-654, MOD:00048 |
enables | increased GO:0017025 TBP-class protein binding with PR:P20226 GTF2D1 |
PMID:11279024 |
decreased GO:0045296 cadherin binding relative to PR:000037196 hCTNNB1/iso:1/UnPhos:3 |
PMID:11279024 |
PR:000037515 hCTNNB1/iso:1/Phos:11 UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046 |
acts_upstream_of_or_within | decreased GO:0008283 cell population proliferation relative to PR:000037772 hCTNNB1/iso:1/UnPhos:4 |
PMID:20307497 |
decreased GO:0060070 canonical Wnt signaling pathway relative to PR:000037772 hCTNNB1/iso:1/UnPhos:4 |
PMID:20307497 |
enables | decreased GO:0003713 transcription coactivator activity relative to PR:000037772 hCTNNB1/iso:1/UnPhos:4 |
PMID:20307497 |
increased GO:0005515 protein binding relative to PR:000037772 hCTNNB1/iso:1/UnPhos:4 |
PMID:16996060; PMID:21152425; PMID:23071615 |
PR:000044474 hCTNNB1/iso:1/Phos:12 UniProtKB:P35222-1, Thr-393, MOD:00047 |
acts_upstream_of_or_within | GO:0016055 Wnt signaling pathway |
PMID:12700239 |
GO:0045944 positive regulation of transcription by RNA polymerase II |
PMID:12700239 |
enables | decreased GO:0005515 protein binding with PR:Q9YGY0 axin |
PMID:19565571 |
PR:000044476 hCTNNB1/iso:1/UnPhos:7 UniProtKB:P35222-1, Thr-393, PR:000026291 |
enables | GO:0005515 protein binding with PR:Q9YGY0 axin |
PMID:19565571 |
PR:000044478 hCTNNB1/iso:1/Phos:13 UniProtKB:P35222-1, Tyr-654, MOD:00048 |
enables | GO:0003713 transcription coactivator activity |
PMID:23640056 |
PR:000044510 hCTNNB1/iso:1/Phos:14 UniProtKB:P35222-1, Ser-552, MOD:00046 |
enables | GO:0071889 14-3-3 protein binding with PR:P63104 hYWHAZ |
PMID:17287208 |