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Protein Ontology report - insulin receptor substrate 1 (human)
PR:P35568 - http://purl.obolibrary.org/obo/PR_P35568
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P35568   
  PRO nameinsulin receptor substrate 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hIRS1
Gene-based: RELATED:IRS1
Other: EXACT:IRS-1 (human)
  Definition"An insulin receptor substrate 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35568] 
  PRO Categoryorganism-gene 
  ParentPR:000009107 insulin receptor substrate 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6125 IRS1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P35568
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:P35568
insulin receptor substrate 1 (human)
hIRS1
"An insulin receptor substrate 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35568]

organism-modification


PR:000045764
insulin receptor substrate 1 phosphorylated 1 (human)
hIRS1/Phos:1
"An insulin receptor substrate 1 (human) that has been phosphorylated at Ser-794. UniProtKB:P35568, Ser-794, MOD:00046." [iPTMnet:P35568, PMID:12624099]

organism-modification


PR:000048052
insulin receptor substrate 1 phosphotyrosine form (human)
hIRS1/PhosTyr+
"An insulin receptor substrate 1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P35568, MOD:00048." [PRO:DNx, Reactome:R-HSA-198366, Reactome:R-HSA-74772]

organism-modification


PR:000048051
insulin receptor substrate 1 phosphorylated 2 (human)
hIRS1/Phos:2
"An insulin receptor substrate 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 612, 662, 732, 896, 941 and 1179 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Tyr-612/Tyr-662/Tyr-732/Tyr-896/Tyr-941/Tyr-1179, MOD:00048." [PRO:DNx, Reactome:R-HSA-2445090]

organism-modification


PR:000067069
insulin receptor substrate 1 phosphorylated 3 (human)
hIRS1/Phos:3
"An insulin receptor substrate 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1229 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Tyr-1229, MOD:00048." [IEDB_epitope:1363086, PRO:DNx]

organism-modification


PR:000084284
insulin receptor substrate 1 methylated 1 (human)
hIRS1/Me:1
"An insulin receptor substrate 1 (human) that has been methylated on the residue at the position equivalent to Cys-728 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Cys-728, MOD:00660." [IEDB_epitope:1009283, PRO:DNx]