back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - activin receptor type-1B (human)
PR:P36896 - http://purl.obolibrary.org/obo/PR_P36896
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P36896   
  PRO nameactivin receptor type-1B (human) 
  Synonyms
PRO-Short-label: EXACT:hACVR1B
Gene-based: RELATED:ACVR1B | ACVRLK4 | ALK4
Other: EXACT:activin receptor type IB (human) | activin receptor-like kinase 4 (human) | ACTR-IB (human) | ALK-4 (human) | serine/threonine-protein kinase receptor R2 (human) | SKR2 (human)
  Definition"An activin receptor type-1B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P36896
  PRO Categoryorganism-gene 
  ParentPR:000000068 activin receptor type-1B
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:172 ACVR1B (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
UniProtKB:P36896
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P36896

activin receptor type-1B (human)

hACVR1B


"An activin receptor type-1B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P36896]


organism-sequence



PR:P36896-1

activin receptor type-1B isoform 1 (human)

hACVR1B/iso:1


"An activin receptor type-1B isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036437

activin receptor type-1B isoform 1 phosphorylated 1 (human)

hACVR1B/iso:1/Phos:1


"An activin receptor type-1B isoform 1 phosphorylated 1 in human." [PMID:12065756, PMID:12665502, PMID:8397373, PMID:8622651, PRO:CNA]

Yes

organism-modification



PR:000036438

activin receptor type-1B isoform 1 phosphorylated 2 (human)

hACVR1B/iso:1/Phos:2


"An activin receptor type-1B isoform 1 phosphorylated 2 in human. UniProtKB:P36896-1, Tyr-380, MOD:00048." [PMID:12112843, PRO:CNA]


organism-sequence



PR:P36896-2

activin receptor type-1B isoform 2 (human)

hACVR1B/iso:2


"An activin receptor type-1B isoform 2 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P36896-3

activin receptor type-1B isoform 3 (human)

hACVR1B/iso:3


"An activin receptor type-1B isoform 3 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P36896-4

activin receptor type-1B isoform h4 (human)

hACVR1B/iso:h4


"An activin receptor type-1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36896-4." [PRO:DNx, UniProtKB:P36896]


organism-sequence



PR:P36896-5

activin receptor type-1B isoform h5 (human)

hACVR1B/iso:h5


"An activin receptor type-1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36896-5." [PRO:DNx, UniProtKB:P36896]


organism-modification



PR:000046256

activin receptor type-1B, signal peptide removed form (human)

hACVR1B/SigPep-


"An activin receptor type-1B (human) that has had the signal peptide removed. UniProtKB:P36896, 24-505." [PRO:DNx, Reactome:R-HSA-205867]


organism-modification



PR:000046257

activin receptor type-1B, signal peptide removed phosphorylated 3 (human)

hACVR1B/SigPep-/Phos:3


"An activin receptor type-1B (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 187, 189, 191 and 193, and phosphothreonine at positions 188 and 206 of the amino acid sequence represented by UniProtKB:P36896. UniProtKB:P36896, 24-505, Ser-187/Ser-189/Ser-191/Ser-193, MOD:00046|Thr-188/Thr-206, MOD:00047." [PRO:DNx, Reactome:R-HSA-205780]


Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0006468 protein phosphorylationPR:000036437 hACVR1B/iso:1/Phos:1 PMID:12065756
GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathwayPR:P36896-1 hACVR1B/iso:1 PMID:11069203

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0016361 activin receptor activity, type IPR:000036437 hACVR1B/iso:1/Phos:1 PMID:8622651
NOT GO:0016361 activin receptor activity, type IPR:P36896-2 hACVR1B/iso:2 PMID:11117535; PMID:8636304
PR:P36896-3 hACVR1B/iso:3 PMID:11117535; PMID:8636304
GO:0046332 SMAD bindingPR:000036437 hACVR1B/iso:1/Phos:1 PMID:12065756

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005886 plasma membranePR:000036437 hACVR1B/iso:1/Phos:1 PMID:8397373
PR:P36896-2 hACVR1B/iso:2 PMID:11117535; PMID:8636304
PR:P36896-3 hACVR1B/iso:3 PMID:11117535; PMID:8636304
GO:0009986 cell surfacePR:000036437 hACVR1B/iso:1/Phos:1 PMID:12665502