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Protein Ontology report - serine/threonine-protein kinase mTOR (human)
PR:P42345 - http://purl.obolibrary.org/obo/PR_P42345
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P42345   
  PRO nameserine/threonine-protein kinase mTOR (human) 
  Synonyms
PRO-Short-label: EXACT:hMTOR
Gene-based: RELATED:FRAP | FRAP1 | FRAP2 | MTOR | RAFT1 | RAPT1
Other: EXACT:FK506-binding protein 12-rapamycin complex-associated protein 1 (human) | FKBP12-rapamycin complex-associated protein (human) | mammalian target of rapamycin (human) | mechanistic target of rapamycin (human) | mTOR (human) | rapamycin and FKBP12 target 1 (human) | rapamycin target protein 1 (human)
  Definition"A serine/threonine-protein kinase mTOR that is encoded in the genome of human." [PRO:CL, UniProtKB:P42345
  PRO Categoryorganism-gene 
  ParentPR:000003041 serine/threonine-protein kinase mTOR
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:3942 MTOR (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P42345
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P42345

serine/threonine-protein kinase mTOR (human)

hMTOR


"A serine/threonine-protein kinase mTOR that is encoded in the genome of human." [PRO:CL, UniProtKB:P42345]

Yes

organism-sequence



PR:P42345-1

serine/threonine-protein kinase mTOR isoform 1 (human)

hMTOR/iso:1


"A serine/threonine-protein kinase mTOR isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045781

serine/threonine-protein kinase mTOR phosphorylated 1 (human)

hMTOR/Phos:1


"A serine/threonine-protein kinase mTOR (human) that has been phosphorylated at Ser-2481. UniProtKB:P42345, Ser-2481, MOD:00046." [iPTMnet:P42345, PMID:10702316]


organism-modification



PR:000068288

serine/threonine-protein kinase mTOR deaminated 1 (human)

hMTOR/Deam:1


"A serine/threonine-protein kinase mTOR (human) that has been deaminated on the residue at the position equivalent to Asn-2093 of the amino acid sequence represented by UniProtKB:P42345. UniProtKB:P42345, Asn-2093, MOD:00684." [IEDB_epitope:1333035, PRO:DNx]


organism-modification



PR:000073464

serine/threonine-protein kinase mTOR deaminated 2 (human)

hMTOR/Deam:2


"A serine/threonine-protein kinase mTOR (human) that has been deaminated on the residue at the position equivalent to Gln-2194 of the amino acid sequence represented by UniProtKB:P42345. UniProtKB:P42345, Gln-2194, MOD:00685." [IEDB_epitope:1564748, PRO:DNx]


organism-modification



PR:000081494

serine/threonine-protein kinase mTOR cysteinylated 1 (human)

hMTOR/Cyst:1


"A serine/threonine-protein kinase mTOR (human) that has been cysteinylated on the residue at the position equivalent to Cys-485 of the amino acid sequence represented by UniProtKB:P42345. UniProtKB:P42345, Cys-485, MOD:00765." [IEDB_epitope:1004671, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P42345 hMTOR acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:11602639
enablesGO:0005515 protein binding with PR:000035446 hTP53/iso:1/Phos:1 PMID:11602639
located_inGO:0005634 nucleus PMID:11602639