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Protein Ontology report - tyrosine-protein kinase SYK isoform 1 (mouse)
PR:P48025-1 - http://purl.obolibrary.org/obo/PR_P48025-1
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P48025-1   
  PRO nametyrosine-protein kinase SYK isoform 1 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSYK/iso:1
  Definition"A tyrosine-protein kinase SYK isoform 1 that is encoded in the genome of mouse." [PRO:CNA] 
  PRO Categoryorganism-sequence 
  ParentPR:000025832 tyrosine-protein kinase SYK isoform 1
PR:P48025 tyrosine-protein kinase SYK (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P48025-1
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-sequence



PR:P48025-1

tyrosine-protein kinase SYK isoform 1 (mouse)

mSYK/iso:1


"A tyrosine-protein kinase SYK isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000025834

tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse)

mSYK/iso:1/Phos:1


"A tyrosine-protein kinase SYK isoform 1 phosphorylated 1 in mouse. UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048." [PMID:15536084, PRO:JAN]

Yes

organism-modification



PR:000049791

tyrosine-protein kinase SYK isoform 1 phosphorylated 2 (mouse)

mSYK/iso:1/Phos:2


"A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342. UniProtKB:P48025-1, Tyr-342, MOD:00048." [PMID:27609517, PRO:LN]


organism-modification



PR:000049792

tyrosine-protein kinase SYK isoform 1 unphosphorylated 2 (mouse)

mSYK/iso:1/UnPhos:2


"A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 342. UniProtKB:P48025-1, Tyr-342, PR:000026291." [PMID:27609517, PRO:LN]


organism-modification



PR:000049793

tyrosine-protein kinase SYK isoform 1 phosphorylated 3 (mouse)

mSYK/iso:1/Phos:3


"A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-346. UniProtKB:P48025-1, Tyr-346, MOD:00048." [PMID:27609517, PRO:LN]


organism-modification



PR:000049794

tyrosine-protein kinase SYK isoform 1 unphosphorylated 3 (mouse)

mSYK/iso:1/UnPhos:3


"A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at position 346. UniProtKB:P48025-1, Tyr-346, PR:000026291." [PMID:27609517, PRO:LN]


organism-modification



PR:000049795

tyrosine-protein kinase SYK isoform 1 phosphorylated 4 (mouse)

mSYK/iso:1/Phos:4


"A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342 and Tyr-346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048." [PMID:27609517, PRO:LN]


organism-modification



PR:000049796

tyrosine-protein kinase SYK isoform 1 phosphorylated 5 (mouse)

mSYK/iso:1/Phos:5


"A tyrosine-protein kinase SYK isoform 1 (mouse) that has been phosphorylated on Tyr-342, Tyr-346, Tyr-519 and Tyr-520. UniProtKB:P48025-1, Tyr-342/Tyr-346/Tyr-519/Tyr-520, MOD:00048." [PMID:27609517, PRO:LN]


organism-modification



PR:000049800

tyrosine-protein kinase SYK isoform 1 phosphorylated 6 (mouse)

mSYK/iso:1/Phos:6


"A tyrosine-protein kinase SYK isoform 1 (mouse) that lacks a phosphorylated Tyr at positions 519 and 520, but it is still phosphorylated at Tyr 342 and 346. UniProtKB:P48025-1, Tyr-342/Tyr-346, MOD:00048|Tyr-519/Tyr-520, PR:000026291." [PMID:27609517, PRO:LN]


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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosisPR:000025834 mSYK/iso:1/Phos:1 PMID:15536084

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0019901 protein kinase bindingPR:000025834 mSYK/iso:1/Phos:1 PMID:15536084
GO:0031625 ubiquitin protein ligase bindingPR:000025834 mSYK/iso:1/Phos:1 PMID:15536084
GO:0043548 phosphatidylinositol 3-kinase bindingPR:000025834 mSYK/iso:1/Phos:1 PMID:15536084