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Protein Ontology report - D(2) dopamine receptor isoform 2 (mouse) PR:P61168-2 - http://purl.obolibrary.org/obo/PR_P61168-2        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:P61168-2      PRO name D(2) dopamine receptor isoform 2 (mouse)    Synonyms PRO-Short-label: EXACT: mDRD2/iso:2 Other: EXACT: D2B (mouse)   Definition "A D(2) dopamine receptor isoform 2 that is encoded in the genome of mouse." [PMID:11069937, PMID:1991517, PRO:KRC]    Comment Note: PMID:1991517 shows cloning of longer cDNA for isoform 1 (aka D2A) and shows distribution of both isoform 1 and isoform 2 mRNAs within mouse tissues. PMID:11069937ZCOLNSPACEZ Use RT-PCR to detect two forms of D2 mRNA that differ by 87 base pairs, corresponding to the two alternatively spliced isoforms of D2 mRNAs. Also detect the D2L mRNA by Northern blot from muscle striatum.    PRO Category organism-sequence    Parent PR:000037413 D(2) dopamine receptor isoform 2 PR:P61168 D(2) dopamine receptor (mouse)   Taxon NCBITaxon:10090 Mus musculus   Term Hierarchy   Visualization DAG: OLS: Back to top Related Cross References   Db identifiers UniProtKB:P61168-2 Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:P61168-2 mDRD2/iso:2 acts_upstream_of_or_within GO:0001975 response to amphetamine MGI_ref:3611062; PMID:12476322 GO:0014059 regulation of dopamine secretion MGI_ref:3655899; PMID:11943831 GO:0032228 regulation of synaptic transmission, GABAergic MGI_ref:3628700; PMID:15489038 GO:0042220 response to cocaine MGI_ref:3655899; PMID:11943831 GO:0043278 response to morphine MGI_ref:3655899; PMID:11943831 GO:0051967 negative regulation of synaptic transmission, glutamatergic MGI_ref:3628700; PMID:15489038 GO:0060160 negative regulation of dopamine receptor signaling pathway MGI_ref:2181304; PMID:11089973 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768; PMID:1991517 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768; PMID:1991517