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Protein Ontology report - DNA-dependent protein kinase catalytic subunit (human)
PR:P78527 - http://purl.obolibrary.org/obo/PR_P78527
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P78527   
  PRO nameDNA-dependent protein kinase catalytic subunit (human) 
  Synonyms
PRO-Short-label: EXACT:hPRKDC
Gene-based: RELATED:HYRC | HYRC1 | PRKDC
Other: EXACT:DNA-PK catalytic subunit (human) | DNA-PKcs (human) | DNPK1 (human)
  Definition"A DNA-dependent protein kinase catalytic subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:P78527
  PRO Categoryorganism-gene 
  ParentPR:000013239 DNA-dependent protein kinase catalytic subunit
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9413 PRKDC (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 40                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P78527
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P78527

DNA-dependent protein kinase catalytic subunit (human)

hPRKDC


"A DNA-dependent protein kinase catalytic subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:P78527]


organism-sequence



PR:P78527-1

DNA-dependent protein kinase catalytic subunit isoform h1 (human)

hPRKDC/iso:h1


"A DNA-dependent protein kinase catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78527-1." [PRO:DNx, UniProtKB:P78527]


organism-sequence



PR:P78527-2

DNA-dependent protein kinase catalytic subunit isoform h2 (human)

hPRKDC/iso:h2


"A DNA-dependent protein kinase catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78527-2." [PRO:DNx, UniProtKB:P78527]


organism-modification



PR:000045858

DNA-dependent protein kinase catalytic subunit phosphorylated 1 (human)

hPRKDC/Phos:1


"A DNA-dependent protein kinase catalytic subunit (human) that has been phosphorylated on the residue at the position equivalent to Thr-2609 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Thr-2609, MOD:00047." [iPTMnet:P78527, PMID:12231622, PMID:15507430]


organism-modification



PR:000048925

DNA-dependent protein kinase catalytic subunit phosphorylated 2 (human)

hPRKDC/Phos:2


"A DNA-dependent protein kinase catalytic subunit (human) that has been post-translationally modified to include phosphothreonine at positions 2609, 2638 and 2647, and phosphoserine at position 2612 of the amino acid sequence represented by UniProtKB:P78527. UniProtKB:P78527, Thr-2609/Thr-2638/Thr-2647, MOD:00047|Ser-2612, MOD:00046." [PRO:DNx, Reactome:R-HSA-76302]


organism-modification



PR:000064712

DNA-dependent protein kinase catalytic subunit ubiquitinated form (human)

hPRKDC/UbiqLys+


"A DNA-dependent protein kinase catalytic subunit (human) that includes at least 1 ubiquitinated lysine. UniProtKB:P78527, MOD:01148." [PRO:DNx, Reactome:R-HSA-8938766]


organism-modification



PR:000065128

DNA-dependent protein kinase catalytic subunit deaminated 1 (human)

hPRKDC/Deam:1


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Gln-3108 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Gln-3108, MOD:00685." [IEDB_epitope:1982506, PRO:DNx]


organism-modification



PR:000065384

DNA-dependent protein kinase catalytic subunit methylated 1 (human)

hPRKDC/Me:1


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-90 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-90, MOD:00660." [IEDB_epitope:1007540, PRO:DNx]


organism-modification



PR:000065506

DNA-dependent protein kinase catalytic subunit methylated 2 (human)

hPRKDC/Me:2


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-1742 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1742, MOD:00660." [IEDB_epitope:1036594, PRO:DNx]


organism-modification



PR:000065699

DNA-dependent protein kinase catalytic subunit methylated 3 (human)

hPRKDC/Me:3


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-301 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-301, MOD:00660." [IEDB_epitope:1003848, PRO:DNx]


organism-modification



PR:000066171

DNA-dependent protein kinase catalytic subunit cysteinylated 1 (human)

hPRKDC/Cyst:1


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-1947 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1947, MOD:00765." [IEDB_epitope:1330775, PRO:DNx]


organism-modification



PR:000066179

DNA-dependent protein kinase catalytic subunit cysteinylated 2 (human)

hPRKDC/Cyst:2


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-1525 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1525, MOD:00765." [IEDB_epitope:1010939, PRO:DNx]


organism-modification



PR:000066290

DNA-dependent protein kinase catalytic subunit methylated 4 (human)

hPRKDC/Me:4


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-2093 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2093, MOD:00660." [IEDB_epitope:1017499, PRO:DNx]


organism-modification



PR:000067718

DNA-dependent protein kinase catalytic subunit deaminated 2 (human)

hPRKDC/Deam:2


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Asn-3339 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Asn-3339, MOD:00684." [IEDB_epitope:2140460, PRO:DNx]


organism-modification



PR:000067997

DNA-dependent protein kinase catalytic subunit methylated 5 (human)

hPRKDC/Me:5


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-2857 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2857, MOD:00660." [IEDB_epitope:1011598, PRO:DNx]


organism-modification



PR:000068468

DNA-dependent protein kinase catalytic subunit cysteinylated 3 (human)

hPRKDC/Cyst:3


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-373 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-373, MOD:00765." [IEDB_epitope:1331930, IEDB_epitope:631759, PRO:DNx]


organism-modification



PR:000069329

DNA-dependent protein kinase catalytic subunit cysteinylated 4 (human)

hPRKDC/Cyst:4


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-1312 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1312, MOD:00765." [IEDB_epitope:875013, PRO:DNx]


organism-modification



PR:000070561

DNA-dependent protein kinase catalytic subunit cysteinylated 5 (human)

hPRKDC/Cyst:5


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-1399 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1399, MOD:00765." [IEDB_epitope:632144, PRO:DNx]


organism-modification



PR:000071726

DNA-dependent protein kinase catalytic subunit deaminated 3 (human)

hPRKDC/Deam:3


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Gln-3130 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Gln-3130, MOD:00685." [IEDB_epitope:1736292, PRO:DNx]


organism-modification



PR:000071792

DNA-dependent protein kinase catalytic subunit methylated 6 (human)

hPRKDC/Me:6


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-931 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-931, MOD:00660." [IEDB_epitope:997154, PRO:DNx]


organism-modification



PR:000072179

DNA-dependent protein kinase catalytic subunit deaminated 4 (human)

hPRKDC/Deam:4


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Asn-1574 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Asn-1574, MOD:00684." [IEDB_epitope:1990134, PRO:DNx]


organism-modification



PR:000072799

DNA-dependent protein kinase catalytic subunit methylated 7 (human)

hPRKDC/Me:7


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-1399 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1399, MOD:00660." [IEDB_epitope:1018395, PRO:DNx]


organism-modification



PR:000074501

DNA-dependent protein kinase catalytic subunit deaminated 5 (human)

hPRKDC/Deam:5


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Gln-1251 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Gln-1251, MOD:00685." [IEDB_epitope:1362830, PRO:DNx]


organism-modification



PR:000075176

DNA-dependent protein kinase catalytic subunit deaminated 6 (human)

hPRKDC/Deam:6


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Asn-3580 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Asn-3580, MOD:00684." [IEDB_epitope:775778, PRO:DNx]


organism-modification



PR:000075367

DNA-dependent protein kinase catalytic subunit methylated 8 (human)

hPRKDC/Me:8


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-25 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-25, MOD:00660." [IEDB_epitope:997234, PRO:DNx]


organism-modification



PR:000076831

DNA-dependent protein kinase catalytic subunit methylated 9 (human)

hPRKDC/Me:9


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-3420 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-3420, MOD:00660." [IEDB_epitope:1054381, PRO:DNx]


organism-modification



PR:000076887

DNA-dependent protein kinase catalytic subunit deaminated 7 (human)

hPRKDC/Deam:7


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Gln-2587 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Gln-2587, MOD:00685." [IEDB_epitope:1578622, PRO:DNx]


organism-modification



PR:000076971

DNA-dependent protein kinase catalytic subunit methylated 10 (human)

hPRKDC/Me:10


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-2863 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2863, MOD:00660." [IEDB_epitope:1022079, PRO:DNx]


organism-modification



PR:000077517

DNA-dependent protein kinase catalytic subunit cysteinylated 6 (human)

hPRKDC/Cyst:6


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-2857 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2857, MOD:00765." [IEDB_epitope:1011597, PRO:DNx]


organism-modification



PR:000077522

DNA-dependent protein kinase catalytic subunit methylated 11 (human)

hPRKDC/Me:11


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-1525 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1525, MOD:00660." [IEDB_epitope:1010940, IEDB_epitope:1010941, IEDB_epitope:1015619, PRO:DNx]


organism-modification



PR:000077601

DNA-dependent protein kinase catalytic subunit cysteinylated 7 (human)

hPRKDC/Cyst:7


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-2584 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2584, MOD:00765." [IEDB_epitope:1031611, PRO:DNx]


organism-modification



PR:000078250

DNA-dependent protein kinase catalytic subunit cysteinylated 8 (human)

hPRKDC/Cyst:8


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-3420 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-3420, MOD:00765." [IEDB_epitope:1054380, PRO:DNx]


organism-modification



PR:000078670

DNA-dependent protein kinase catalytic subunit deaminated 8 (human)

hPRKDC/Deam:8


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Gln-2795 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Gln-2795, MOD:00685." [IEDB_epitope:1853196, PRO:DNx]


organism-modification



PR:000078985

DNA-dependent protein kinase catalytic subunit methylated 12 (human)

hPRKDC/Me:12


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-285 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-285, MOD:00660." [IEDB_epitope:1017360, PRO:DNx]


organism-modification



PR:000080045

DNA-dependent protein kinase catalytic subunit methylated 13 (human)

hPRKDC/Me:13


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-1312 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-1312, MOD:00660." [IEDB_epitope:998505, PRO:DNx]


organism-modification



PR:000081381

DNA-dependent protein kinase catalytic subunit deaminated 9 (human)

hPRKDC/Deam:9


"A DNA-dependent protein kinase catalytic subunit (human) that has been deaminated on the residue at the position equivalent to Asn-250 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Asn-250, MOD:00684." [IEDB_epitope:1992837, PRO:DNx]


organism-modification



PR:000081468

DNA-dependent protein kinase catalytic subunit methylated 14 (human)

hPRKDC/Me:14


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-2584 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2584, MOD:00660." [IEDB_epitope:1018758, IEDB_epitope:1048005, PRO:DNx]


organism-modification



PR:000081628

DNA-dependent protein kinase catalytic subunit cysteinylated 9 (human)

hPRKDC/Cyst:9


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-2435 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2435, MOD:00765." [IEDB_epitope:1584139, PRO:DNx]


organism-modification



PR:000082116

DNA-dependent protein kinase catalytic subunit cysteinylated 10 (human)

hPRKDC/Cyst:10


"A DNA-dependent protein kinase catalytic subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-729 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-729, MOD:00765." [IEDB_epitope:1567878, PRO:DNx]


organism-modification



PR:000082943

DNA-dependent protein kinase catalytic subunit methylated 15 (human)

hPRKDC/Me:15


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-2363 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-2363, MOD:00660." [IEDB_epitope:1033025, PRO:DNx]


organism-modification



PR:000083170

DNA-dependent protein kinase catalytic subunit methylated 16 (human)

hPRKDC/Me:16


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-373 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-373, MOD:00660." [IEDB_epitope:1010977, IEDB_epitope:1015645, PRO:DNx]


organism-modification



PR:000083604

DNA-dependent protein kinase catalytic subunit methylated 17 (human)

hPRKDC/Me:17


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-3912 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-3912, MOD:00660." [IEDB_epitope:1017322, PRO:DNx]


organism-modification



PR:000085085

DNA-dependent protein kinase catalytic subunit methylated 18 (human)

hPRKDC/Me:18


"A DNA-dependent protein kinase catalytic subunit (human) that has been methylated on the residue at the position equivalent to Cys-795 of the amino acid sequence represented by UniProtKB:P78527-1. Example: UniProtKB:P78527-1, Cys-795, MOD:00660." [IEDB_epitope:1037322, PRO:DNx]