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Protein Ontology report - activin receptor type-1 (human)
PR:Q04771 - http://purl.obolibrary.org/obo/PR_Q04771
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q04771   
  PRO nameactivin receptor type-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hACVR1
Gene-based: RELATED:ACVR1 | ACVRLK2
Other: EXACT:activin receptor type I (human) | activin receptor-like kinase 2 (human) | ACTR-I (human) | ALK-2 (human) | serine/threonine-protein kinase receptor R1 (human) | SKR1 (human)
  Definition"An activin receptor type-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q04771] 
  CommentRequested by=PubChem. 
  PRO Categoryorganism-gene 
  ParentPR:000000067 activin receptor type-1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:171 ACVR1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q04771
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q04771 activin receptor type-1 (human)
hACVR1

organism-sequence


PR:000000200 activin receptor type-1 sequence variant R206H (human)
hACVR1/var:R206H
Yes
organism-sequence


PR:Q04771-1 activin receptor type-1 isoform 1 (human)
hACVR1/iso:1

organism-modification


PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
hACVR1/iso:1/SigPep-/Phos:1
Yes
organism-modification


PR:000068633 activin receptor type-1 cysteinylated 1 (human)
hACVR1/Cyst:1

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathwayPR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742; PMID:8389764

Disease Associated GO Term
Protein Forms & Complexes
Evidence
DO:13374 fibrodysplasia ossificans progressivaPR:000000200 hACVR1/var:R206H PMID:8397373

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004675 transmembrane receptor protein serine/threonine kinase activityPR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8389764
GO:0048185 activin bindingPR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:000000200 hACVR1/var:R206H PMID:8397373
PR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742; PMID:8397373
GO:0048179 activin receptor complexPR:000036435 hACVR1/iso:1/SigPep-/Phos:1 PMID:8242742