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Protein Ontology report - cell division cycle protein 20 homolog (human)
PR:Q12834 - http://purl.obolibrary.org/obo/PR_Q12834
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q12834   
  PRO namecell division cycle protein 20 homolog (human) 
  Synonyms
PRO-Short-label: EXACT:hCDC20
Gene-based: RELATED:CDC20
Other: EXACT:p55CDC (human)
  Definition"A cell division cycle protein 20 homolog that is encoded in the genome of human." [PMID:11030144, PMID:20624902, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000005188 cell division cycle protein 20 homolog
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1723 CDC20 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q12834
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q12834
cell division cycle protein 20 homolog (human)
hCDC20
"A cell division cycle protein 20 homolog that is encoded in the genome of human." [PMID:11030144, PMID:20624902, PRO:KER]
Yes
Yes
organism-sequence


PR:Q12834-1
cell division cycle protein 20 homolog isoform 1 (human)
hCDC20/iso:1
"A cell division cycle protein 20 homolog isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000035369
cell division cycle protein 20 homolog unphosphorylated form (human)
hCDC20/PhosRes-
"A cell division cycle protein 20 homolog unphosphorylated form in human." [PMID:15525512, PRO:KER]
Yes
organism-modification


PR:000035371
cell division cycle protein 20 homolog phosphorylated 1 (human)
hCDC20/Phos:1
"A cell division cycle protein 20 homolog phosphorylated 1 in human. This phosphorylated form occurs during mitotic splindle disruption (or with Nocodazole treatment) via BUB1 kinase activity. UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047." [PMID:15525512, PRO:KER]
Yes
organism-modification


PR:000035440
cell division cycle protein 20 homolog phosphorylated 2 (human)
hCDC20/Phos:2
"A cell division cycle protein 20 homolog phosphorylated 2 in human." [PMID:11030144, PRO:KER]

organism-modification


PR:000035442
cell division cycle protein 20 homolog phosphorylated 3 (human)
hCDC20/Phos:3
"A cell division cycle protein 20 homolog phosphorylated 3 in human. Potential sites Ser-41, Ser-408, Ser-452, Thr-55, Thr-59, Thr-70, Thr-106, Thr-157." [PMID:22566641, PRO:KER]
Yes
organism-modification


PR:000046658
cell division cycle protein 20 homolog ubiquitinated form (human)
hCDC20/UbiqLys+
"A cell division cycle protein 20 homolog (human) that includes at least one ubiquitinated lysine. UniProtKB:Q12834, MOD:01148." [PRO:DNx, Reactome:R-HSA-6783069]

organism-modification


PR:000066860
cell division cycle protein 20 homolog cysteinylated 1 (human)
hCDC20/Cyst:1
"A cell division cycle protein 20 homolog (human) that has been cysteinylated on the residue at the position equivalent to Cys-403 of the amino acid sequence represented by UniProtKB:Q12834. UniProtKB:Q12834, Cys-403, MOD:00765." [IEDB_epitope:632268, PRO:DNx]

organism-modification


PR:000076113
cell division cycle protein 20 homolog methylated 1 (human)
hCDC20/Me:1
"A cell division cycle protein 20 homolog (human) that has been methylated on the residue at the position equivalent to Cys-403 of the amino acid sequence represented by UniProtKB:Q12834. UniProtKB:Q12834, Cys-403, MOD:00660." [IEDB_epitope:1019369, PRO:DNx]

organism-modification


PR:000079638
cell division cycle protein 20 homolog methylated 2 (human)
hCDC20/Me:2
"A cell division cycle protein 20 homolog (human) that has been methylated on the residue at the position equivalent to Cys-165 of the amino acid sequence represented by UniProtKB:Q12834. UniProtKB:Q12834, Cys-165, MOD:00660." [IEDB_epitope:1026934, PRO:DNx]

organism-modification


PR:000082105
cell division cycle protein 20 homolog deaminated 1 (human)
hCDC20/Deam:1
"A cell division cycle protein 20 homolog (human) that has been deaminated on the residue at the position equivalent to Asn-103 of the amino acid sequence represented by UniProtKB:Q12834. UniProtKB:Q12834, Asn-103, MOD:00684." [IEDB_epitope:1990372, PRO:DNx]

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hCDC20 forms found in complexes   

hCDC20 Component
 Complexes
PR:Q12834 hCDC20 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:000035575 BUB1B:CDC20 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035369 hCDC20/PhosRes- acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:15525512
enablesGO:0004842 ubiquitin-protein transferase activity PMID:15525512
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
GO:0005515 protein binding PMID:15525512
located_inGO:0000776 kinetochore PMID:15525512
PR:000035371 hCDC20/Phos:1
UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035369 cdc20 unphosphorylated (human) PMID:15525512
enablesdecreased GO:0004842 ubiquitin-protein transferase activity relative to PR:000035369 cdc20 unphosphorylated (human) PMID:15525512
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
GO:0005515 protein binding PMID:15525512
located_inGO:0000776 kinetochore PMID:15525512
PR:000035442 hCDC20/Phos:3
Potential sites Ser-41, Ser-408, Ser-452, Thr-55, Thr-59, Thr-70, Thr-106, Thr-157		 enablesdecreased GO:0005515 protein binding with PR:O60566 BUB1B PMID:22566641
PR:Q12834 hCDC20 enablesGO:0005515 protein binding with PR:O60566 BUB1B PMID:20624902
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:20624902