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Protein Ontology report - TNF receptor-associated factor 3 (human)
PR:Q13114 - http://purl.obolibrary.org/obo/PR_Q13114
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q13114   
  PRO nameTNF receptor-associated factor 3 (human) 
  Synonyms
PRO-Short-label: EXACT:hTRAF3
Gene-based: RELATED:CAP-1 | CRAF1 | TRAF3 | TRAFAMN
Other: EXACT:CD40 receptor-associated factor 1 (human) | CD40-binding protein (human) | CD40BP (human) | LAP1 (human) | LMP1-associated protein 1 (human) | RING-type E3 ubiquitin transferase TRAF3 (human)
  Definition"A TNF receptor-associated factor 3 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-gene 
  ParentPR:000002289 TNF receptor-associated factor 3
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12033 TRAF3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q13114
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q13114
TNF receptor-associated factor 3 (human)
hTRAF3
"A TNF receptor-associated factor 3 that is encoded in the genome of human." [PRO:CNA]

Yes
organism-sequence


PR:Q13114-1
TNF receptor-associated factor 3 isoform 1 (human)
hTRAF3/iso:1
"A TNF receptor-associated factor 3 isoform 1 that is encoded in the genome of human." [PRO:JAN]

organism-sequence


PR:Q13114-2
TNF receptor-associated factor 3 isoform h2 (human)
hTRAF3/iso:h2
"A TNF receptor-associated factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13114-2." [PRO:DNx, UniProtKB:Q13114]

organism-modification


PR:000036032
TNF receptor-associated factor 3 K63-polyubiquitinated form (human)
hTRAF3/K63polyUbiq+
"A TNF receptor-associated factor 3 K63-polyubiquitinated form in human. UniProtKB:Q13114, PR:000044772." [Reactome:R-HSA-936402]

Yes
organism-modification


PR:000064750
TNF receptor-associated factor 3 ubiquitinated form (human)
hTRAF3/UbiqLys+
"A TNF receptor-associated factor 3 (human) that includes at least 1 ubiquitinated lysine. UniProtKB:Q13114, MOD:01148." [PRO:DNx, Reactome:R-HSA-936556]

organism-modification


PR:000069328
TNF receptor-associated factor 3 cysteinylated 1 (human)
hTRAF3/Cyst:1
"A TNF receptor-associated factor 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-117 of the amino acid sequence represented by UniProtKB:Q13114-1. Example: UniProtKB:Q13114-1, Cys-117, MOD:00765." [IEDB_epitope:1578434, PRO:DNx]

organism-modification


PR:000083316
TNF receptor-associated factor 3 deaminated 1 (human)
hTRAF3/Deam:1
"A TNF receptor-associated factor 3 (human) that has been deaminated on the residue at the position equivalent to Gln-278 of the amino acid sequence represented by UniProtKB:Q13114-1. Example: UniProtKB:Q13114-1, Gln-278, MOD:00685." [IEDB_epitope:1777217, PRO:DNx]

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hTRAF3 forms found in complexes   

hTRAF3 Component
 Complexes
PR:000036032 hTRAF3/K63polyUbiq+ PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000037315 K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:Q13114 hTRAF3 PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037310 traf3:ticam1:activated TLR3 complex (human)
PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)