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Documentation
Protein Ontology report - cullin-1 isoform 1 (human)
PR:Q13616-1 -
http://purl.obolibrary.org/obo/PR_Q13616-1
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:Q13616-1
PRO name
cullin-1 isoform 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hCUL1/iso:1
Definition
"A fungal/metazoan cullin-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
PRO Category
organism-sequence
Parent
PR:000000267
fungal/metazoan cullin-1 isoform 1
PR:Q13616
cullin-1 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
0
Organism-Sequence
1
Modification
0
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q13616-1
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
organism-sequence
PR:Q13616-1
cullin-1 isoform 1 (human)
hCUL1/iso:1
Yes
organism-modification
PR:000036454
cullin-1 isoform 1 neddylated 1 (human)
hCUL1/iso:1/Nedd:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036454
hCUL1/iso:1/Nedd:1
UniProtKB:Q13616-1, Lys-720, MOD:01150
acts_upstream_of_or_within
GO:0008285
negative regulation of cell population proliferation
PMID:8681378
GO:0031146
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
PMID:10713156
;
PMID:10921923
GO:0051726
regulation of cell cycle
PMID:8681378
GO:0097193
intrinsic apoptotic signaling pathway
PMID:8681378
located_in
GO:0019005
SCF ubiquitin ligase complex
PMID:10713156
;
PMID:10921923
;
PMID:17098746
PR:Q13616-1
hCUL1/iso:1
enables
GO:0005515
protein binding
with
PR:P62877-1
PMID:12504026
;
PMID:15537541
GO:0005515
protein binding
with
PR:Q86VP6-1
PMID:12504026
;
PMID:15537541
located_in
NOT
GO:0019005
SCF ubiquitin ligase complex
PMID:10713156
;
PMID:10921923
;
PMID:12504026
