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Protein Ontology report - inhibitor of nuclear factor kappa-B kinase subunit epsilon (human)
PR:Q14164 - http://purl.obolibrary.org/obo/PR_Q14164
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14164   
  PRO nameinhibitor of nuclear factor kappa-B kinase subunit epsilon (human) 
  Synonyms
PRO-Short-label: EXACT:hIKBKE
Gene-based: RELATED:IKBKE | IKKE | IKKI | KIAA0151
Other: EXACT:I-kappa-B kinase epsilon (human) | IkBKE (human) | IKK-E (human) | IKK-epsilon (human) | IKK-i (human) | inducible I kappa-B kinase (human)
  Definition"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of human." [PMID:10882136, PMID:17327220, PRO:CNA, UniProtKB:Q14164
  PRO Categoryorganism-gene 
  ParentPR:000001778 inhibitor of nuclear factor kappa-B kinase subunit epsilon
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:14552 IKBKE (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14164
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:Q14164

inhibitor of nuclear factor kappa-B kinase subunit epsilon (human)

hIKBKE


"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of human." [PMID:10882136, PMID:17327220, PRO:CNA, UniProtKB:Q14164]


organism-sequence



PR:Q14164-1

inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 (human)

hIKBKE/iso:1


"An inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q14164-2

inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform h2 (human)

hIKBKE/iso:h2


"An inhibitor of nuclear factor kappa-B kinase subunit epsilon (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14164-2." [PRO:DNx, UniProtKB:Q14164]


organism-modification



PR:000028691

inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 (human)

hIKBKE/Phos:1


"An inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 in human. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046." [PMID:10421793, PRO:CNA, Reactome:R-HSA-450278]


Yes
organism-modification



PR:000064755

inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated and sumoylated 1 (human)

hIKBKE/PhosSumo:1


"An inhibitor of nuclear factor kappa-B kinase subunit epsilon (human) that has been phosphorylated on the residue at the position equivalent to Ser-172 and sumoylated on the residue at the position equivalent to Lys-231 of the amino acid sequence represented by UniProtKB:Q14164-1. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046|Lys-231, MOD:01149." [PRO:DNx, Reactome:R-HSA-4755535]


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hIKBKE forms found in complexes   

hIKBKE Component
Complexes
PR:000028691 hIKBKE/Phos:1 PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)