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Protein Ontology report - protein-tyrosine kinase 2-beta (human)
PR:Q14289 - http://purl.obolibrary.org/obo/PR_Q14289
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14289   
  PRO nameprotein-tyrosine kinase 2-beta (human) 
  Synonyms
PRO-Short-label: EXACT:hPTK2B
Gene-based: RELATED:FAK2 | PTK2B | PYK2 | RAFTK
Other: EXACT:CADTK (human) | CAK-beta (human) | CAKB (human) | calcium-dependent tyrosine kinase (human) | calcium-regulated non-receptor proline-rich tyrosine kinase (human) | cell adhesion kinase beta (human) | FADK 2 (human) | focal adhesion kinase 2 (human) | proline-rich tyrosine kinase 2 (human) | related adhesion focal tyrosine kinase (human)
  Definition"A focal adhesion kinase 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q14289
  PRO Categoryorganism-gene 
  ParentPR:000003032 focal adhesion kinase 2
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9612 PTK2B (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14289
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:Q14289

protein-tyrosine kinase 2-beta (human)

hPTK2B


"A focal adhesion kinase 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q14289]


organism-sequence



PR:Q14289-1

protein-tyrosine kinase 2-beta isoform 1 (human)

hPTK2B/iso:1


"A focal adhesion kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

organism-sequence



PR:Q14289-2

protein-tyrosine kinase 2-beta isoform 2 (human)

hPTK2B/iso:2


"A focal adhesion kinase 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000048954

protein-tyrosine kinase 2-beta phosphotyrosine form (human)

hPTK2B/PhosTyr+


"A protein-tyrosine kinase 2-beta (human) that includes at least one phosphorylated tyrosine. UniProtKB:Q14289, MOD:00048." [PRO:DNx, Reactome:R-HSA-508515]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

organism-modification



PR:000048953

protein-tyrosine kinase 2-beta phosphorylated 2 (human)

hPTK2B/Phos:2


"A protein-tyrosine kinase 2-beta (human) that has been phosphorylated on the residue at the position equivalent to Tyr-402 of the amino acid sequence represented by UniProtKB:Q14289. UniProtKB:Q14289, Tyr-402, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218721]


organism-modification



PR:000065247

protein-tyrosine kinase 2-beta methylated 1 (human)

hPTK2B/Me:1


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-246 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-246, MOD:00660." [IEDB_epitope:1002474, PRO:DNx]


organism-modification



PR:000070234

protein-tyrosine kinase 2-beta cysteinylated 1 (human)

hPTK2B/Cyst:1


"A protein-tyrosine kinase 2-beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-246 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-246, MOD:00765." [IEDB_epitope:1587468, PRO:DNx]


organism-modification



PR:000071896

protein-tyrosine kinase 2-beta deaminated 1 (human)

hPTK2B/Deam:1


"A protein-tyrosine kinase 2-beta (human) that has been deaminated on the residue at the position equivalent to Gln-329 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Gln-329, MOD:00685." [IEDB_epitope:1349689, PRO:DNx]


organism-modification



PR:000077476

protein-tyrosine kinase 2-beta deaminated 2 (human)

hPTK2B/Deam:2


"A protein-tyrosine kinase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-193 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Asn-193, MOD:00684." [IEDB_epitope:635229, PRO:DNx]


organism-modification



PR:000078700

protein-tyrosine kinase 2-beta methylated 2 (human)

hPTK2B/Me:2


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-534 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-534, MOD:00660." [IEDB_epitope:1058353, PRO:DNx]


organism-modification



PR:000079503

protein-tyrosine kinase 2-beta methylated 3 (human)

hPTK2B/Me:3


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-120 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-120, MOD:00660." [IEDB_epitope:1010336, IEDB_epitope:1015039, PRO:DNx]


organism-modification



PR:000081549

protein-tyrosine kinase 2-beta methylated 4 (human)

hPTK2B/Me:4


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-298 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-298, MOD:00660." [IEDB_epitope:1051088, PRO:DNx]


organism-modification



PR:000083633

protein-tyrosine kinase 2-beta cysteinylated 2 (human)

hPTK2B/Cyst:2


"A protein-tyrosine kinase 2-beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-534 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-534, MOD:00765." [IEDB_epitope:1031252, IEDB_epitope:638607, PRO:DNx]


organism-modification



PR:000083918

protein-tyrosine kinase 2-beta phosphorylated 1 (human)

hPTK2B/Phos:1


"A protein-tyrosine kinase 2-beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-530 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Ser-530, MOD:00046." [IEDB_epitope:1374869, PRO:DNx]


organism-modification



PR:000085313

protein-tyrosine kinase 2-beta methylated 5 (human)

hPTK2B/Me:5


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-310 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-310, MOD:00660." [IEDB_epitope:1026113, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036642 hPTK2B/iso:1/Phos:1
UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048
acts_upstream_of_or_withinGO:0070098 chemokine-mediated signaling pathway PMID:11698270