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Protein Ontology report - interferon regulatory factor 3 (human)
PR:Q14653 - http://purl.obolibrary.org/obo/PR_Q14653
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14653   
  PRO nameinterferon regulatory factor 3 (human) 
  Synonyms
PRO-Short-label: EXACT:hIRF3
Gene-based: RELATED:IRF3
Other: EXACT:IRF-3 (human)
  Definition"An interferon regulatory factor 3 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-gene 
  ParentPR:000002045 interferon regulatory factor 3
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6118 IRF3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14653
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q14653 interferon regulatory factor 3 (human)
hIRF3

Yes
organism-sequence


PR:Q14653-1 interferon regulatory factor 3 isoform 1 (human)
hIRF3/iso:1

organism-modification


PR:000025763 interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
hIRF3/iso:1/Phos:1
Yes
Yes
organism-modification


PR:000045489 interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
hIRF3/iso:1/Phos:2

Yes
organism-sequence


PR:Q14653-2 interferon regulatory factor 3 isoform h2 (human)
hIRF3/iso:h2

organism-sequence


PR:Q14653-3 interferon regulatory factor 3 isoform h3 (human)
hIRF3/iso:h3

organism-sequence


PR:Q14653-4 interferon regulatory factor 3 isoform h4 (human)
hIRF3/iso:h4

organism-sequence


PR:Q14653-5 interferon regulatory factor 3 isoform h5 (human)
hIRF3/iso:h5

organism-modification


PR:000028702 interferon regulatory factor 3 unmodified form (human)
hIRF3/UnMod

Yes
organism-modification


PR:000045488 interferon regulatory factor 3 phosphorylated 1 (human)
hIRF3/Phos:1

Yes
organism-modification


PR:000061027 interferon regulatory factor 3, initiator methionine removed form (human)
hIRF3/InitMet-

organism-modification


PR:000065516 interferon regulatory factor 3 methylated 1 (human)
hIRF3/Me:1

organism-modification


PR:000075605 interferon regulatory factor 3 cysteinylated 1 (human)
hIRF3/Cyst:1

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hIRF3 forms found in complexes   

hIRF3 Component
 Complexes
PR:000025763 hIRF3/iso:1/Phos:1 PR:000036002 IRF3-P:IRF3-P:KPNA4 complex (human)
PR:000028702 hIRF3/UnMod PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000045488 hIRF3/Phos:1 PR:000025765 IRF3-P:IRF3-P complex (human)
PR:000045489 hIRF3/iso:1/Phos:2 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:Q14653 hIRF3 PR:000036045 IRF3:XPO1 complex (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:000025763 hIRF3/iso:1/Phos:1 PMID:10805757

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005829 cytosolPR:000025763 hIRF3/iso:1/Phos:1 Reactome:REACT_7149