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Protein Ontology report - mediator of DNA damage checkpoint protein 1 (human)
PR:Q14676 - http://purl.obolibrary.org/obo/PR_Q14676
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14676   
  PRO namemediator of DNA damage checkpoint protein 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hMDC1
Gene-based: RELATED:KIAA0170 | MDC1 | NFBD1
Other: EXACT:nuclear factor with BRCT domains 1 (human)
  Definition"A mediator of DNA damage checkpoint protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14676] 
  PRO Categoryorganism-gene 
  ParentPR:000010258 mediator of DNA damage checkpoint protein 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:21163 MDC1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14676
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q14676
mediator of DNA damage checkpoint protein 1 (human)
hMDC1
"A mediator of DNA damage checkpoint protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14676]

organism-sequence


PR:Q14676-1
mediator of DNA damage checkpoint protein 1 isoform h1 (human)
hMDC1/iso:h1
"A mediator of DNA damage checkpoint protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14676-1." [PRO:DNx, UniProtKB:Q14676]

organism-sequence


PR:Q14676-2
mediator of DNA damage checkpoint protein 1 isoform h2 (human)
hMDC1/iso:h2
"A mediator of DNA damage checkpoint protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14676-2." [PRO:DNx, UniProtKB:Q14676]

organism-sequence


PR:Q14676-3
mediator of DNA damage checkpoint protein 1 isoform h3 (human)
hMDC1/iso:h3
"A mediator of DNA damage checkpoint protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14676-3." [PRO:DNx, UniProtKB:Q14676]

organism-sequence


PR:Q14676-4
mediator of DNA damage checkpoint protein 1 isoform h4 (human)
hMDC1/iso:h4
"A mediator of DNA damage checkpoint protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14676-4." [PRO:DNx, UniProtKB:Q14676]

organism-modification


PR:000045929
mediator of DNA damage checkpoint protein 1 phosphorylated 1 (human)
hMDC1/Phos:1
"A mediator of DNA damage checkpoint protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-98 of the amino acid sequence represented by UniProtKB:Q14676-1. Example: UniProtKB:Q14676-1, Thr-98, MOD:00047." [iPTMnet:Q14676, PMID:21705321]

organism-modification


PR:000048353
mediator of DNA damage checkpoint protein 1 phosphorylated 2 (human)
hMDC1/Phos:2
"A mediator of DNA damage checkpoint protein 1 (human) that has been post-translationally modified to include phosphothreonine at positions 4, 699, 719, 752 and 765 of the amino acid sequence represented by UniProtKB:Q14676. UniProtKB:Q14676, Thr-4/Thr-699/Thr-719/Thr-752/Thr-765, MOD:00047." [PRO:DNx, Reactome:R-HSA-75236]

organism-modification


PR:000064720
mediator of DNA damage checkpoint protein 1 sumoylated 1 (human)
hMDC1/Sumo:1
"A mediator of DNA damage checkpoint protein 1 (human) that has been sumoylated on the residue at the position equivalent to Lys-1840 of the amino acid sequence represented by UniProtKB:Q14676-1. Example: UniProtKB:Q14676-1, Lys-1840, MOD:01149." [PRO:DNx, Reactome:R-HSA-4570473, Reactome:R-HSA-4570546]

organism-modification


PR:000064766
mediator of DNA damage checkpoint protein 1 phosphorylated and sumoylated 1 (human)
hMDC1/PhosSumo:1
"A mediator of DNA damage checkpoint protein 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-4, Thr-699, Thr-719, Thr-752 and Thr-765, and sumoylated on the residue at the position equivalent to Lys-1840 of the amino acid sequence represented by UniProtKB:Q14676-1. Example: UniProtKB:Q14676-1, Thr-4/Thr-699/Thr-719/Thr-752/Thr-765, MOD:00047|Lys-1840, MOD:01149." [PRO:DNx, Reactome:R-HSA-5684061]

organism-modification


PR:000064784
mediator of DNA damage checkpoint protein 1 phosphorylated, sumoylated, and ubiquitinated 1 (human)
hMDC1/PhosSumoUbiq:1
"A mediator of DNA damage checkpoint protein 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-4, Thr-699, Thr-719, Thr-752 and Thr-765, and sumoylated on the residue at the position equivalent to Lys-1840 of the amino acid sequence represented by UniProtKB:Q14676-1 and that includes at least 1 ubiquitinated lysine. Example: UniProtKB:Q14676-1, Thr-4/Thr-699/Thr-719/Thr-752/Thr-765, MOD:00047|Lys-1840, MOD:01149|MOD:01148." [PRO:DNx, Reactome:R-HSA-5684074]

organism-modification


PR:000078098
mediator of DNA damage checkpoint protein 1 methylated 1 (human)
hMDC1/Me:1
"A mediator of DNA damage checkpoint protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-62 of the amino acid sequence represented by UniProtKB:Q14676-1. Example: UniProtKB:Q14676-1, Cys-62, MOD:00660." [IEDB_epitope:1043895, PRO:DNx]