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Protein Ontology report - sonic hedgehog protein (human)
PR:Q15465 - http://purl.obolibrary.org/obo/PR_Q15465
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q15465   
  PRO namesonic hedgehog protein (human) 
  Synonyms
PRO-Short-label: EXACT:hSHH
Gene-based: RELATED:SHH
Other: EXACT:HHG-1 (human) | Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human) | ShhNC (human)
  Definition"A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465
  PRO Categoryorganism-gene 
  ParentPR:000014841 sonic hedgehog protein
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:10848 SHH (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 28                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q15465
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:Q15465

sonic hedgehog protein (human)

hSHH


"A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465]


organism-modification



PR:000037274

sonic hedgehog protein N-product dually lipidated 1 (human)

hSHH/Clv:Nter/2*Lipid:1


"A sonic hedgehog protein N-product in human that has been further modified on the N-terminal Cys residue by palmitoylation and the C-terminal Gly residue by cholesterylation. UniProtKB:Q15465, 24-197, Cys-24, MOD:00069|Gly-197, MOD:00314." [PMID:9593755, PRO:CNA]


organism-modification



PR:000060317

sonic hedgehog protein sequence variant L382P, signal peptide removed form (human)

hSHH/var:L382P/SigPep-


"A sonic hedgehog protein (human) that has a Pro residue at the position equivalent to Leu-382 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Leu-382, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5358428]


organism-modification



PR:000060418

sonic hedgehog protein sequence variant G196V, signal peptide removed form (human)

hSHH/var:G196V/SigPep-


"A sonic hedgehog protein (human) that has a Val residue at the position equivalent to Gly-196 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Gly-196, CHEBI:30015." [PRO:DNx, Reactome:R-HSA-5358433]


organism-modification



PR:000060438

sonic hedgehog protein sequence variant C198S, signal peptide removed ubiquitinated form (human)

hSHH/var:C198S/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Ser residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Cys-198, CHEBI:29999|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387341, Reactome:R-HSA-5387354]


organism-modification



PR:000060458

sonic hedgehog protein sequence variant G196V, signal peptide removed ubiquitinated form (human)

hSHH/var:G196V/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Val residue at the position equivalent to Gly-196 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Gly-196, CHEBI:30015|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387343, Reactome:R-HSA-5387362]


organism-modification



PR:000060483

sonic hedgehog protein sequence variant W117G, signal peptide removed ubiquitinated form (human)

hSHH/var:W117G/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Gly residue at the position equivalent to Trp-117 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Trp-117, CHEBI:29947|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387345, Reactome:R-HSA-5387361]


organism-modification



PR:000060485

sonic hedgehog protein sequence variant W117G, signal peptide removed form (human)

hSHH/var:W117G/SigPep-


"A sonic hedgehog protein (human) that has a Gly residue at the position equivalent to Trp-117 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Trp-117, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-5358404]


organism-modification



PR:000060562

sonic hedgehog protein sequence variant W117R, signal peptide removed form (human)

hSHH/var:W117R/SigPep-


"A sonic hedgehog protein (human) that has an Arg residue at the position equivalent to Trp-117 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Trp-117, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5358401]


organism-modification



PR:000060621

sonic hedgehog protein sequence variant A373T, signal peptide removed form (human)

hSHH/var:A373T/SigPep-


"A sonic hedgehog protein (human) that has a Thr residue at the position equivalent to Ala-373 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Ala-373, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-5358448]


organism-modification



PR:000060800

sonic hedgehog protein sequence variant F377S, signal peptide removed form (human)

hSHH/var:F377S/SigPep-


"A sonic hedgehog protein (human) that has a Ser residue at the position equivalent to Phe-377 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Phe-377, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-5358427]


organism-modification



PR:000060869

sonic hedgehog protein sequence variant R381P, signal peptide removed ubiquitinated form (human)

hSHH/var:R381P/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Pro residue at the position equivalent to Arg-381 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Arg-381, CHEBI:50342|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387342, Reactome:R-HSA-5387359]


organism-modification



PR:000061125

sonic hedgehog protein sequence variant A376D, signal peptide removed form (human)

hSHH/var:A376D/SigPep-


"A sonic hedgehog protein (human) that has an Asp residue at the position equivalent to Ala-376 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Ala-376, CHEBI:29958." [PRO:DNx, Reactome:R-HSA-5358445]


organism-modification



PR:000061219

sonic hedgehog protein sequence variant F377S, signal peptide removed ubiquitinated form (human)

hSHH/var:F377S/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Ser residue at the position equivalent to Phe-377 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Phe-377, CHEBI:29999|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387351, Reactome:R-HSA-5387364]


organism-modification



PR:000061558

sonic hedgehog protein sequence variant G196E, signal peptide removed form (human)

hSHH/var:G196E/SigPep-


"A sonic hedgehog protein (human) that has a Glu residue at the position equivalent to Gly-196 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Gly-196, CHEBI:29972." [PRO:DNx, Reactome:R-HSA-5358437]


organism-modification



PR:000061958

sonic hedgehog protein sequence variant A383T, signal peptide removed form (human)

hSHH/var:A383T/SigPep-


"A sonic hedgehog protein (human) that has a Thr residue at the position equivalent to Ala-383 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Ala-383, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-5358444]


organism-modification



PR:000062404

sonic hedgehog protein sequence variant C198S, signal peptide removed form (human)

hSHH/var:C198S/SigPep-


"A sonic hedgehog protein (human) that has a Ser residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Cys-198, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-5358439]


organism-modification



PR:000062597

sonic hedgehog protein sequence variant G196E, signal peptide removed ubiquitinated form (human)

hSHH/var:G196E/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Glu residue at the position equivalent to Gly-196 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Gly-196, CHEBI:29972|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387339, Reactome:R-HSA-5387356]


organism-modification



PR:000062637

sonic hedgehog protein sequence variant A383T, signal peptide removed ubiquitinated form (human)

hSHH/var:A383T/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Thr residue at the position equivalent to Ala-383 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Ala-383, CHEBI:30013|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387348, Reactome:R-HSA-5387366]


organism-modification



PR:000062821

sonic hedgehog protein sequence variant A376D, signal peptide removed ubiquitinated form (human)

hSHH/var:A376D/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has an Asp residue at the position equivalent to Ala-376 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Ala-376, CHEBI:29958|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387340, Reactome:R-HSA-5387355]


organism-modification



PR:000062925

sonic hedgehog protein sequence variant A373T, signal peptide removed ubiquitinated form (human)

hSHH/var:A373T/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Thr residue at the position equivalent to Ala-373 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Ala-373, CHEBI:30013|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387346, Reactome:R-HSA-5387363]


organism-modification



PR:000063074

sonic hedgehog protein sequence variant W117R, signal peptide removed ubiquitinated form (human)

hSHH/var:W117R/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has an Arg residue at the position equivalent to Trp-117 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Trp-117, CHEBI:29952|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387347, Reactome:R-HSA-5387353]


organism-modification



PR:000063484

sonic hedgehog protein, signal peptide removed form (human)

hSHH/SigPep-


"A sonic hedgehog protein (human) that has had the signal peptide removed. UniProtKB:Q15465, 24-462." [PRO:DNx, Reactome:R-HSA-9815791]


organism-modification



PR:000063556

sonic hedgehog protein sequence variant R381P, signal peptide removed form (human)

hSHH/var:R381P/SigPep-


"A sonic hedgehog protein (human) that has a Pro residue at the position equivalent to Arg-381 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Arg-381, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5358425]


organism-modification



PR:000063771

sonic hedgehog protein sequence variant C198F, signal peptide removed ubiquitinated form (human)

hSHH/var:C198F/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Phe residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Cys-198, CHEBI:29997|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387349, Reactome:R-HSA-5387365]


organism-modification



PR:000063895

sonic hedgehog protein sequence variant C198F, signal peptide removed form (human)

hSHH/var:C198F/SigPep-


"A sonic hedgehog protein (human) that has a Phe residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, Cys-198, CHEBI:29997." [PRO:DNx, Reactome:R-HSA-5358441]


organism-modification



PR:000064527

sonic hedgehog protein sequence variant H374R, signal peptide removed form (human)

hSHH/var:H374R/SigPep-


"A sonic hedgehog protein (human) that has an Arg residue at the position equivalent to His-374 of the amino acid sequence represented by UniProtKB:Q15465 and that has had the signal peptide removed. UniProtKB:Q15465, 24-462, His-374, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5358430]


organism-modification



PR:000064548

sonic hedgehog protein sequence variant L382P, signal peptide removed ubiquitinated form (human)

hSHH/var:L382P/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has a Pro residue at the position equivalent to Leu-382 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, Leu-382, CHEBI:50342|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387344, Reactome:R-HSA-5387357]


organism-modification



PR:000064560

sonic hedgehog protein sequence variant H374R, signal peptide removed ubiquitinated form (human)

hSHH/var:H374R/SigPep-/UbiqLys+


"A sonic hedgehog protein (human) that has an Arg residue at the position equivalent to His-374 of the amino acid sequence represented by UniProtKB:Q15465, that has had the signal peptide removed, and that includes at least 1 ubiquitinated lysine. UniProtKB:Q15465, 24-462, His-374, CHEBI:29952|MOD:01148." [PRO:DNx, Reactome:R-HSA-5387352, Reactome:R-HSA-5387360]