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Protein Ontology report - presenilin-2 isoform PS2beta (mouse)
PR:Q61144-2 - http://purl.obolibrary.org/obo/PR_Q61144-2
 
    Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q61144-2   
  PRO namepresenilin-2 isoform PS2beta (mouse) 
  Synonyms
PRO-Short-label: EXACT:mPSEN2/iso:PS2beta
  Definition"A presenilin-2 isoform PS2beta that is encoded in the genome of mouse. The sequence is shorter (361 residues long) than isoform 1 sharing the same sequence up to residue 357, followed by the sequence SKGA." [PMID:19376115, PRO:KRC] 
  CommentNote: This isoform has been seen endogeneously in microsomal fraction from mouse brain. 
  PRO Categoryorganism-sequence 
  ParentPR:000036853 presenilin-2 isoform PS2beta
PR:Q61144 presenilin-2 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q61144-2
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q61144-2 mPSEN2/iso:PS2beta
The sequence is shorter (361 residues long) than isoform 1 sharing the same sequence up to residue 357, followed by the sequence SKGA
acts_upstream_of_or_withinGO:0031333 negative regulation of protein-containing complex assembly MGI_ref:3843380; PMID:19376115
GO:0032091 negative regulation of protein binding MGI_ref:3843380; PMID:19376115
located_inGO:0005783 endoplasmic reticulum MGI_ref:3843380; PMID:19376115