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Protein Ontology report - mothers against decapentaplegic homolog 2 (mouse)
PR:Q62432 - http://purl.obolibrary.org/obo/PR_Q62432
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q62432   
  PRO namemothers against decapentaplegic homolog 2 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSMAD2
Gene-based: RELATED:Madh2 | Madr2 | Smad2
Other: EXACT:MAD homolog 2 (mouse) | Mad-related protein 2 (mouse) | mMad2 | mothers against DPP homolog 2 (mouse) | SMAD 2 (mouse) | SMAD family member 2 (mouse)
  Definition"A smad2 that is encoded in the genome of mouse." [OMA:Q62432, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000000364 smad2
PR:000029032 Mus musculus protein
  Gene TemplateMGI:108051 Smad2 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q62432
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:Q62432

mothers against decapentaplegic homolog 2 (mouse)

mSMAD2


"A smad2 that is encoded in the genome of mouse." [OMA:Q62432, PRO:DNx]


organism-sequence



PR:Q62432-1

mothers against decapentaplegic homolog 2 isoform Long (mouse)

mSMAD2/iso:Long


"A smad2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000025942

smad2 isoform Long phosphorylated 1 (mouse)

mSMAD2/iso:Long/Phos:1


"A smad2 isoform Long phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046." [PMID:8980228, PMID:9346966]

Yes

Yes
organism-modification



PR:000036482

smad2 isoform Long phosphorylated and ubiquitinated form (mouse)

mSMAD2/iso:Long/PhosUbiq+


"A smad2 isoform Long phosphorylated and ubiquitinated form in mouse. UniProtKB:Q62432-1, MOD:00696|MOD:01148." [PMID:15496141, PRO:CNA]


organism-modification



PR:000036555

smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)

mSMAD2/iso:Long/PhosUbiq:1


"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]

Yes

organism-sequence



PR:Q62432-2

mothers against decapentaplegic homolog 2 isoform Short (mouse)

mSMAD2/iso:Short


"A smad2 isoform Short that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q62432]


organism-modification



PR:000025943

smad2 isoform Short phosphorylated 1 (mouse)

mSMAD2/iso:Short/Phos:1


"A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]

Yes

Yes
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mSMAD2 forms found in complexes   

mSMAD2 Component
Complexes
PR:000025942 mSMAD2/iso:Long/Phos:1 PR:000025944 smad2-smad4 protein complex 1 (mouse)
PR:000025943 mSMAD2/iso:Short/Phos:1 PR:000025945 smad2-smad4 protein complex 2 (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025942 mSMAD2/iso:Long/Phos:1
UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046
acts_upstream_of_or_withinGO:0007165 signal transduction PMID:11262418
GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11262418
enablesGO:0003713 transcription coactivator activity PMID:15282343
GO:0046332 SMAD binding PMID:11043574
located_inGO:0005634 nucleus PMID:11557747
PR:000025943 mSMAD2/iso:Short/Phos:1
UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046
acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:15630024
enablesGO:0003700 DNA-binding transcription factor activity PMID:15630024
PR:000036555 mSMAD2/iso:Long/PhosUbiq:1
UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148
acts_upstream_of_or_withinGO:0007165 signal transduction PMID:15496141
enablesNOT GO:0003713 transcription coactivator activity PMID:15496141
PR:Q62432-1 mSMAD2/iso:Long acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:11557747
located_inGO:0005737 cytoplasm PMID:14701940