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Protein Ontology report - mothers against decapentaplegic homolog 2 (mouse)
PR:Q62432 - http://purl.obolibrary.org/obo/PR_Q62432
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q62432   
  PRO namemothers against decapentaplegic homolog 2 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSMAD2
Gene-based: RELATED:Madh2 | Madr2 | Smad2
Other: EXACT:MAD homolog 2 (mouse) | Mad-related protein 2 (mouse) | mMad2 | mothers against DPP homolog 2 (mouse) | SMAD 2 (mouse) | SMAD family member 2 (mouse)
  Definition"A smad2 that is encoded in the genome of mouse." [OMA:Q62432, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000000364 smad2
PR:000029032 Mus musculus protein
  Gene TemplateMGI:108051 Smad2 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q62432
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q62432 mothers against decapentaplegic homolog 2 (mouse)
mSMAD2

organism-sequence


PR:Q62432-1 mothers against decapentaplegic homolog 2 isoform Long (mouse)
mSMAD2/iso:Long
Yes
organism-modification


PR:000025942 smad2 isoform Long phosphorylated 1 (mouse)
mSMAD2/iso:Long/Phos:1
Yes
Yes
organism-modification


PR:000036482 smad2 isoform Long phosphorylated and ubiquitinated form (mouse)
mSMAD2/iso:Long/PhosUbiq+

organism-modification


PR:000036555 smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
mSMAD2/iso:Long/PhosUbiq:1
Yes
organism-sequence


PR:Q62432-2 mothers against decapentaplegic homolog 2 isoform Short (mouse)
mSMAD2/iso:Short

organism-modification


PR:000025943 smad2 isoform Short phosphorylated 1 (mouse)
mSMAD2/iso:Short/Phos:1
Yes
Yes
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mSMAD2 forms found in complexes   

mSMAD2 Component
 Complexes
PR:000025942 mSMAD2/iso:Long/Phos:1 PR:000025944 smad2-smad4 protein complex 1 (mouse)
PR:000025943 mSMAD2/iso:Short/Phos:1 PR:000025945 smad2-smad4 protein complex 2 (mouse)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007165 signal transductionPR:000025942 mSMAD2/iso:Long/Phos:1 PMID:11262418
PR:000036555 mSMAD2/iso:Long/PhosUbiq:1 PMID:15496141
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000025942 mSMAD2/iso:Long/Phos:1 PMID:11262418
PR:000025943 mSMAD2/iso:Short/Phos:1 PMID:15630024
PR:Q62432-1 mSMAD2/iso:Long PMID:11557747

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003700 DNA-binding transcription factor activityPR:000025943 mSMAD2/iso:Short/Phos:1 PMID:15630024
GO:0003713 transcription coactivator activityPR:000025942 mSMAD2/iso:Long/Phos:1 PMID:15282343
NOT GO:0003713 transcription coactivator activityPR:000036555 mSMAD2/iso:Long/PhosUbiq:1 PMID:15496141
GO:0046332 SMAD bindingPR:000025942 mSMAD2/iso:Long/Phos:1 PMID:11043574

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000025942 mSMAD2/iso:Long/Phos:1 PMID:11557747
GO:0005737 cytoplasmPR:Q62432-1 mSMAD2/iso:Long PMID:14701940