back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - pro-neuregulin-1, membrane-bound isoform (mouse)
PR:Q6DR98 - http://purl.obolibrary.org/obo/PR_Q6DR98
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q6DR98   
  PRO namepro-neuregulin-1, membrane-bound isoform (mouse) 
  Synonyms
PRO-Short-label: EXACT:mNRG1
Gene-based: NARROW:Nrg1
Other: EXACT:pro-NRG1 (mouse)
  Definition"A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of mouse." [PRO:KRC] 
  PRO Categoryorganism-gene 
  ParentPR:000029032 Mus musculus protein
PR:000029649 pro-neuregulin-1, membrane-bound isoform
  Gene TemplateMGI:96083 Nrg1 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
UniProtKB:Q6DR98
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q6DR98 pro-neuregulin-1, membrane-bound isoform (mouse)
mNRG1
Yes
organism-sequence


PR:000044837 neuregulin-1 type I-beta4a (mouse)
mNRG1/iso:Ibeta4a

organism-modification


PR:000044838 neuregulin-1 type I-beta4a transmembrane precursor (mouse)
mNRG1/iso:Ibeta4a/precursor

organism-modification


PR:000044839 neuregulin-1 type I-beta4a mature form (mouse)
mNRG1/iso:Ibeta4a/mature

union


PR:000044840 neuregulin-1 type III (mouse)
mNRG1/iso:III
Yes




PR:A0A140LIG9 neuregulin-1 type III-beta1c (mouse)





PR:A0A5F8MPT0 neuregulin-1 type III-beta3 (mouse)





PR:Q6DR99 neuregulin-1 type III-beta1a (mouse)

organism-sequence


PR:A0A140LIG9 neuregulin-1 type III-beta1c (mouse)
mNRG1/iso:IIIbeta1c

organism-sequence


PR:Q3URY7 neuregulin-1 type III-beta1c sequence variant S499Y (mouse)
mNRG1/iso:IIIbeta1c/var:S499Y

organism-modification


PR:000044825 neuregulin-1 type III-beta1c transmembrane precursor (mouse)
mNRG1/iso:IIIbeta1c/precursor

organism-sequence


PR:A0A140LIP8 neuregulin-1 type beta2 (mouse)
mNRG1/iso:beta2

organism-sequence


PR:A0A140LJC1 neuregulin-1 type I-alpha2a (mouse)
mNRG1/iso:Ialpha2a

organism-modification


PR:000044842 neuregulin-1 type I-alpha2a transmembrane precursor (mouse)
mNRG1/iso:Ialpha2a/precursor

organism-sequence


PR:A0A5F8MPT0 neuregulin-1 type III-beta3 (mouse)
mNRG1/iso:IIIbeta3

organism-sequence


PR:Q8BX76 neuregulin-1 type III-beta3 sequence variant D40N (mouse)
mNRG1/iso:IIIbeta3/var:D40N

organism-sequence


PR:Q6DR98-1 neuregulin-1 type I-beta1a (mouse)
mNRG1/iso:Ibeta1a

organism-modification


PR:000044821 neuregulin-1 type I-beta1a mature form (mouse)
mNRG1/iso:Ibeta1a/mature
Yes
organism-modification


PR:000044823 neuregulin-1 type I-beta1a transmembrane precursor (mouse)
mNRG1/iso:Ibeta1a/precursor

organism-sequence


PR:Q6DR99 neuregulin-1 type III-beta1a (mouse)
mNRG1/iso:IIIbeta1a
Yes
organism-modification


PR:000044824 neuregulin-1 type III-beta1a transmembrane precursor (mouse)
mNRG1/iso:IIIbeta1a/precursor
Yes
organism-modification


PR:000044843 neuregulin-1 intracellular domain (mouse)
mNRG1/Clv:intracellular
Yes
Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001964 startle responsePR:000044840 mNRG1/iso:III MGI_ref:3803029; PMID:18596162
GO:0008366 axon ensheathmentPR:000044840 mNRG1/iso:III MGI_ref:3590355; PMID:16129398
GO:0022008 neurogenesisPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
GO:0031643 positive regulation of myelinationPR:000044840 mNRG1/iso:III MGI_ref:4420197; PMID:18080294
PR:000044840 mNRG1/iso:III MGI_ref:4420197; PMID:18080294
PR:Q6DR99 mNRG1/iso:IIIbeta1a MGI_ref:3042336; PMID:15044753
NOT GO:0031643 positive regulation of myelinationPR:Q6DR98 mNRG1 MGI_ref:3042336; PMID:15044753
GO:0045773 positive regulation of axon extensionPR:000044824 mNRG1/iso:IIIbeta1a/precursor MGI_ref:4461331; PMID:20610754
NOT GO:0045773 positive regulation of axon extensionPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
GO:0045944 positive regulation of transcription by RNA polymerase IIPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
NOT GO:0048709 oligodendrocyte differentiationPR:000044840 mNRG1/iso:III MGI_ref:4420197; PMID:18080294
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylationPR:000044821 mNRG1/iso:Ibeta1a/mature MGI_ref:3625788; PMID:11116142
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transductionPR:000044840 mNRG1/iso:III MGI_ref:3796800; PMID:18458158
GO:0060999 positive regulation of dendritic spine developmentPR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
GO:2000010 positive regulation of protein localization to cell surfacePR:000044840 mNRG1/iso:III MGI_ref:3796800; PMID:18458158

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005576 extracellular regionPR:000044821 mNRG1/iso:Ibeta1a/mature MGI_ref:3625788; PMID:11116142
GO:0005634 nucleusPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
GO:0009897 external side of plasma membranePR:Q6DR98 mNRG1 MGI_ref:3625788; PMID:11116142
GO:0030424 axonPR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
PR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
GO:0030425 dendritePR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754
GO:0030673 axolemmaPR:000044840 mNRG1/iso:III MGI_ref:3796800; PMID:18458158
GO:0044297 cell bodyPR:000044840 mNRG1/iso:III MGI_ref:4461331; PMID:20610754