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Protein Ontology report - mothers against decapentaplegic homolog 3 isoform 1 (mouse)
PR:Q8BUN5-1 - http://purl.obolibrary.org/obo/PR_Q8BUN5-1
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q8BUN5-1   
  PRO namemothers against decapentaplegic homolog 3 isoform 1 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSMAD3/iso:1
  Definition"A smad3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA] 
  PRO Categoryorganism-sequence 
  ParentPR:000000475 smad3 isoform 1
PR:Q8BUN5 mothers against decapentaplegic homolog 3 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8BUN5-1
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-sequence



PR:Q8BUN5-1

mothers against decapentaplegic homolog 3 isoform 1 (mouse)

mSMAD3/iso:1


"A smad3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036558

smad3 isoform 1 phosphorylated 1 (mouse)

mSMAD3/iso:1/Phos:1


"A smad3 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046." [PMID:10823886, PMID:12943993, PMID:15282343, PMID:15464984, PMID:9702197, PRO:CNA]

Yes

organism-modification



PR:000036560

smad3 isoform 1 phosphorylated 2 (mouse)

mSMAD3/iso:1/Phos:2


"A smad3 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046." [PMID:15241418, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036561

smad3 isoform 1 phosphorylated 3 (mouse)

mSMAD3/iso:1/Phos:3


"A smad3 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046." [PMID:10197981, PRO:CNA, PRO:DAN]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:Q8BUN5-1 mSMAD3/iso:1 PMID:12543979

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0003690 double-stranded DNA bindingPR:000036558 mSMAD3/iso:1/Phos:1 PMID:15282343
GO:0003700 DNA-binding transcription factor activityPR:000036558 mSMAD3/iso:1/Phos:1 PMID:10823886; PMID:12943993
PR:000036560 mSMAD3/iso:1/Phos:2 PMID:15241418
NOT GO:0003713 transcription coactivator activityPR:000036561 mSMAD3/iso:1/Phos:3 PMID:10197981
GO:0005515 protein bindingPR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
PR:Q8BUN5-1 mSMAD3/iso:1 PMID:12154125
GO:0008134 transcription factor bindingPR:000036558 mSMAD3/iso:1/Phos:1 PMID:15464984; PMID:9702197

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000036558 mSMAD3/iso:1/Phos:1 PMID:12943993; PMID:15282343
GO:0005667 transcription factor complexPR:000036558 mSMAD3/iso:1/Phos:1 PMID:9702197
GO:0005737 cytoplasmPR:000036561 mSMAD3/iso:1/Phos:3 PMID:10197981