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Protein Ontology report - lysosomal cobalamin transport escort protein LMBD1 (mouse)
PR:Q8K0B2 - http://purl.obolibrary.org/obo/PR_Q8K0B2
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q8K0B2   
  PRO namelysosomal cobalamin transport escort protein LMBD1 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mLMBRD1
Gene-based: RELATED:Lmbrd1
Other: EXACT:LMBD1 (mouse) | LMBR1 domain-containing protein 1 (mouse) | protein N90b (mouse)
  Definition"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of mouse." [OMA:Q8K0B2, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000029032 Mus musculus protein
PR:000032677 lysosomal cobalamin transport escort protein LMBD1
  Gene TemplateMGI:1915671 Lmbrd1 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8K0B2
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q8K0B2
lysosomal cobalamin transport escort protein LMBD1 (mouse)
mLMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of mouse." [OMA:Q8K0B2, PRO:DNx]

organism-sequence


PR:Q8K0B2-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)
mLMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
Yes
organism-sequence


PR:Q8K0B2-2
lysosomal cobalamin transport escort protein LMBD1 isoform 2 (mouse)
mLMBRD1/iso:2
"A lysosomal cobalamin transport escort protein LMBD1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-2." [PMID:16141072, PRO:HJD]

organism-sequence


PR:Q8K0B2-3
lysosomal cobalamin transport escort protein LMBD1 isoform 3 (mouse)
mLMBRD1/iso:3
"A lysosomal cobalamin transport escort protein LMBD1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-3." [PMID:16141072, PRO:HJD]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8K0B2-1 mLMBRD1/iso:1 acts_upstream_of_or_withinGO:0038016 insulin receptor internalization MGI_ref:5543853; PMID:24078630
NOT GO:0043408 regulation of MAPK cascade MGI_ref:5543853; PMID:24078630
GO:0046325 negative regulation of glucose import MGI_ref:5543853; PMID:24078630
GO:0046627 negative regulation of insulin receptor signaling pathway MGI_ref:5543853; PMID:24078630
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5543853; PMID:24078630