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Protein Ontology report - CREB-binding protein (human)
PR:Q92793 - http://purl.obolibrary.org/obo/PR_Q92793
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q92793   
  PRO nameCREB-binding protein (human) 
  Synonyms
PRO-Short-label: EXACT:hCREBBP
Gene-based: RELATED:CBP | CREBBP
Other: EXACT:histone lysine acetyltransferase CREBBP (human) | protein-lysine acetyltransferase CREBBP (human)
  Definition"A CREB-binding protein that is encoded in the genome of human." [PMID:11331617] 
  PRO Categoryorganism-gene 
  ParentPR:000000090 CREB-binding protein
PR:000027108 transcription adapter with TAZ, KIX and bromo-domains (human)
  Gene TemplateHGNC:2348 CREBBP (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q92793
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:Q92793 CREB-binding protein (human)
hCREBBP

organism-sequence


PR:000000266 CREB-binding protein sequence variant R1378P (human)
hCREBBP/var:R1378P
Yes
organism-sequence


PR:Q92793-1 CREB-binding protein isoform 1 (human)
hCREBBP/iso:1
Yes
organism-sequence


PR:Q92793-2 CREB-binding protein isoform h2 (human)
hCREBBP/iso:h2

organism-modification


PR:000064816 CREB-binding protein sumoylated 1 (human)
hCREBBP/Sumo:1

organism-modification


PR:000067783 CREB-binding protein phosphorylated 1 (human)
hCREBBP/Phos:1

organism-modification


PR:000080126 CREB-binding protein phosphorylated 2 (human)
hCREBBP/Phos:2

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006355 regulation of DNA-templated transcriptionPR:Q92793-1 hCREBBP/iso:1 PMID:12169688; PMID:7913207
GO:0045893 positive regulation of DNA-templated transcriptionPR:Q92793-1 hCREBBP/iso:1 PMID:11742995

Disease Associated GO Term
Protein Forms & Complexes
Evidence
DO:1933 Rubinstein-Taybi syndromePR:000000266 hCREBBP/var:R1378P PMID:11331617

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003713 transcription coactivator activityPR:Q92793-1 hCREBBP/iso:1 PMID:10733899; PMID:10893273; PMID:12169688; PMID:12586840; PMID:8684459
GO:0004402 histone acetyltransferase activityPR:Q92793-1 hCREBBP/iso:1 PMID:11742995
NOT GO:0004402 histone acetyltransferase activityPR:000000266 hCREBBP/var:R1378P PMID:11331617
GO:0005515 protein bindingPR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
PR:Q92793-1 hCREBBP/iso:1 PMID:11799127
GO:0016407 acetyltransferase activityPR:Q92793-1 hCREBBP/iso:1 PMID:11742995

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0000123 histone acetyltransferase complexPR:Q92793-1 hCREBBP/iso:1 PMID:9742083
GO:0005634 nucleusPR:Q92793-1 hCREBBP/iso:1 PMID:7913207
SO:0001559 polypeptide_loss_of_function_variantPR:000000266 hCREBBP/var:R1378P PMID:11331617