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Protein Ontology report - mitotic spindle assembly checkpoint protein MAD1 (human)
PR:Q9Y6D9 - http://purl.obolibrary.org/obo/PR_Q9Y6D9
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q9Y6D9   
  PRO namemitotic spindle assembly checkpoint protein MAD1 (human) 
  Synonyms
PRO-Short-label: EXACT:hMAD1L1
Gene-based: RELATED:MAD1 | MAD1L1 | TXBP181
Other: EXACT:HsMAD1 | MAD1-like protein 1 (human) | mitotic arrest deficient 1-like protein 1 (human) | mitotic checkpoint MAD1 protein homolog (human) | Tax-binding protein 181 (human)
  Definition"A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human." [PMID:10198256, PMID:12837246, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000010037 mitotic spindle assembly checkpoint protein MAD1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6762 MAD1L1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q9Y6D9
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:Q9Y6D9

mitotic spindle assembly checkpoint protein MAD1 (human)

hMAD1L1


"A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human." [PMID:10198256, PMID:12837246, PRO:KER]

Yes

Yes
organism-sequence



PR:Q9Y6D9-1

mitotic spindle assembly checkpoint protein MAD1 isoform h1 (human)

hMAD1L1/iso:h1


"A mitotic spindle assembly checkpoint protein MAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6D9-1." [PRO:DNx, UniProtKB:Q9Y6D9]


organism-sequence



PR:Q9Y6D9-3

mitotic spindle assembly checkpoint protein MAD1 isoform h2 (human)

hMAD1L1/iso:h2


"A mitotic spindle assembly checkpoint protein MAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6D9-3." [PRO:DNx, UniProtKB:Q9Y6D9]


organism-sequence



PR:Q9Y6D9-4

mitotic spindle assembly checkpoint protein MAD1 isoform h3 (human)

hMAD1L1/iso:h3


"A mitotic spindle assembly checkpoint protein MAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6D9-4." [PRO:DNx, UniProtKB:Q9Y6D9]


organism-modification



PR:000035562

mitotic spindle assembly checkpoint protein MAD1 phosphorylated 1 (human)

hMAD1L1/Phos:1


"A mitotic spindle assembly checkpoint protein MAD1 phosphorylated 1 in human." [PMID:10198256, PRO:KER]


organism-modification



PR:000046109

mitotic spindle assembly checkpoint protein MAD1 phosphorylated 2 (human)

hMAD1L1/Phos:2


"A mitotic spindle assembly checkpoint protein MAD1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-214 of the amino acid sequence represented by UniProtKB:Q9Y6D9-1. Example: UniProtKB:Q9Y6D9-1, Ser-214, MOD:00046." [iPTMnet:Q9Y6D9, PMID:24728176]


organism-modification



PR:000075297

mitotic spindle assembly checkpoint protein MAD1 methylated 1 (human)

hMAD1L1/Me:1


"A mitotic spindle assembly checkpoint protein MAD1 (human) that has been methylated on the residue at the position equivalent to Cys-662 of the amino acid sequence represented by UniProtKB:Q9Y6D9-1. Example: UniProtKB:Q9Y6D9-1, Cys-662, MOD:00660." [IEDB_epitope:1060563, IEDB_epitope:998358, PRO:DNx]


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hMAD1L1 forms found in complexes   

hMAD1L1 Component
Complexes
PR:Q9Y6D9 hMAD1L1 PR:000035567 BUB1:BUB3:MAD1L1 complex (human)
PR:000035568 MAD1:MAD2 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Y6D9 hMAD1L1 enablesGO:0005515 protein binding with PR:O43683 BUB1 PMID:10198256
GO:0005515 protein binding with PR:O43684 BUB3 PMID:10198256
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:10198256
located_inGO:0000776 kinetochore PMID:20624902