[Term]
id: PR:000000098
name: growth/differentiation factor
def: "A TGF-beta-like cystine-knot cytokine that is closely related to the BMP family. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release the bioactive C-terminal peptide. GDFs act as signaling molecules during embryonic tendon/ligament formation." [PRO:CNA]
comment: Category=family.
is_a: PR:000000008 ! TGF-beta-like cystine-knot cytokine