[Term]
id: PR:000002151
name: DNA-binding protein Ikaros isoform 2
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-2 or a 1:1 ortholog thereof." [PRO:DAN, PRO:HJD, PMID:18623087, PMID:8895580]
comment: Category=sequence. Note: This isoform lacks four N-terminal zinc finger domains in comparison to isoform 1, thus functioning as a dominant negative.
synonym: "IKZF1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform Ik6" EXACT []
property_value: has_archetype PR:Q03267-2
is_a: PR:000001811 ! DNA-binding protein Ikaros