[Term]
id: PR:000025586
name: gamma-secretase C-terminal fragment 59
def: "An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal chain of 59 amino acid residues produced by gamma-secretase cleavage of certain amyloid-beta A4 proteolytic cleavage products. Example: UniProtKB:P05067-1, 712-770." [PRO:DAN]
comment: Category=modification. Requested by=Alzforum.
synonym: "APP-CTF(59)" EXACT PRO-short-label [PRO:DAN]
synonym: "AICD-59" EXACT []
synonym: "AID(59)" EXACT []
synonym: "Amyloid intracellular domain 59" EXACT []
synonym: "gamma-CTF(59)" EXACT []
is_a: PR:000019036 ! amyloid-beta precursor protein proteolytic cleavage product
relationship: derives_from PR:000025744 ! precursor of amyloid-beta precursor protein gamma-secretase C-terminal fragment