[Term]
id: PR:000027805
name: cellular tumor antigen p53 isoform 1 ubiquitinated 1
def: "A cellular tumor antigen p53 isoform 1 that has been ubiquitinated at two highly conserved Lys residues in the C-terminal region of the DNA-binding domain. This modification promotes proteasomal degradation of p53. Example: UniProtKB:P04637-1, Lys-291/Lys-292, MOD:01148." [PRO:PD, PMID:19536131]
comment: Category=modification.
synonym: "TP53/iso:1/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003036 ! cellular tumor antigen p53 isoform 1
relationship: has_part MOD:01148 ! ubiquitinylated lysine