[Term]
id: PR:000027834
name: cellular tumor antigen p53 isoform 1 O-glycosylated 1
def: "A cellular tumor antigen p53 isoform 1 that has been O-glycosylated on a Ser residue located in the DNA-binding domain. This modification stabilizes p53 by blocking ubiquitin-dependent proteolysis and also inhibits phosphorylation of p53 at Thr-155. Example: UniProtKB:P04637-1, Ser-149, MOD:00805|Thr-155, PR:000026291." [PRO:DAN, PRO:PD, PMID:16964247]
comment: Category=modification.
synonym: "TP53/iso:1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003036 ! cellular tumor antigen p53 isoform 1
relationship: has_part MOD:00805 ! O-(N-acetylamino)glucosyl-L-serine