[Term]
id: PR:000037315
name: K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
def: "A K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PRO:DAN, PRO:VS, PMID:16306936, PMID:16306937, Reactome:R-HSA-2213008]
comment: Category=organism-complex. Requested by=TLR.
synonym: "K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human)" EXACT [Reactome:R-HSA-2213008]
is_a: PR:000037314 ! K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex
relationship: has_component CHEBI:67208 {cardinality="1"} ! dsRNA
relationship: has_component PR:000036032 {cardinality="2"} ! TNF receptor-associated factor 3 K63-polyubiquitinated form (human)
relationship: has_component PR:000037305 {cardinality="2"} ! Toll-like receptor 3, signal peptide removed form (human)
relationship: has_component PR:Q8IUC6 {cardinality="2"} ! TIR domain-containing adapter molecule 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens