[Term]
id: PR:000048357
name: E3 ubiquitin-protein ligase Mdm2 phosphorylated 2 (human)
def: "An E3 ubiquitin-protein ligase Mdm2 (human) that has been post-translationally modified to include phosphoserine at positions 166 and 188 of the amino acid sequence represented by UniProtKB:Q00987. UniProtKB:Q00987, Ser-166/Ser-188, MOD:00046." [PRO:DNx, Reactome:R-HSA-198638, Reactome:R-HSA-6793669]
comment: Category=organism-modification.
synonym: "hMDM2/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q00987, Ser-166/Ser-188, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-198638 "PR:000048357 located_in GO:0005829"
xref: Reactome:R-HSA-6793669 "PR:000048357 located_in GO:0005654"
is_a: PR:Q00987 ! E3 ubiquitin-protein ligase Mdm2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens