[Term]
id: PR:000050277
name: non-structural protein 8 (SARS-CoV-2)
def: "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3942-3943 and 4140-4141." [PRO:DAN, GenPept:YP_009725304, UniProtKB:P0DTC1, UniProtKB:P0DTD1]
comment: Category=organism-modification. Note: 198 aa protein.
synonym: "rep/Clv:nsp8 (SARS2)" EXACT PRO-short-label [PRO:DAN]
synonym: "nsp8 (SARS-CoV-2)" EXACT [UniProtKB:P0DTC1, UniProtKB:P0DTD1]
synonym: "PRO_0000449626" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "PRO_0000449642" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P0DTC1, 3943-4140" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P0DTD1, 3943-4140" EXACT PRO-proteoform-std [PRO:DAN]
xref: GenPept:YP_009725304
xref: GenPept:YP_009742615
is_a: PR:000050281 ! rep gene proteolytic cleavage product (SARS-CoV-2)
relationship: only_in_taxon NCBITaxon:2697049 ! Severe acute respiratory syndrome coronavirus 2