[Term]
id: PR:000050392
name: presepsin (human)
def: "A CD14 molecule, signal peptide removed form that has been cleaved by plasma proteases to yield a soluble 13kD N-terminal fragment in human." [PRO:DAN, PMID:16258819, PMID:21740312, PMID:25215141]
comment: Category=organism-modification. Note: The cleavage position indicated in [PMID:21740312] is based on a synthetic construct; the true point of cleavage is unknown. It is believed that presepsin is derived from a membrane-bound precursor as opposed to a secreted form [PMID:16258819].
synonym: "hPSEP" EXACT PRO-short-label [PRO:DAN]
synonym: "P-SEP (human)" EXACT [PRO:DAN]
synonym: "PSEP (human)" EXACT [PRO:DAN]
synonym: "sCD14-ST (human)" EXACT [PRO:DAN]
synonym: "soluble CD14 subtype (human)" EXACT [PRO:DAN]
synonym: "soluble cluster of differentiation 14 subtype (human)" EXACT [PRO:DAN]
is_a: PR:000018574 ! CD14 molecule, signal peptide removed form
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens