[Term]
id: PR:000060462
name: histone H2AX, initiator methionine removed phosphorylated 3 (human)
def: "A histone H2AX (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Ser-140 and Tyr-143 of the amino acid sequence represented by UniProtKB:P16104. UniProtKB:P16104, 2-143, Ser-140, MOD:00046|Tyr-143, MOD:00048." [PRO:DNx, Reactome:R-HSA-5683953]
comment: Category=organism-modification.
synonym: "hH2AFX/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S140,Y143-H2AFX" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-5683953]
synonym: "UniProtKB:P16104, 2-143, Ser-140, MOD:00046|Tyr-143, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5683953 "PR:000060462 located_in GO:0005654"
is_a: PR:P16104 ! histone H2AX (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens