[Term]
id: PR:000062031
name: receptor tyrosine-protein kinase erbB-2, signal peptide removed phosphorylated 8 (human)
def: "A receptor tyrosine-protein kinase erbB-2 (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-1023, Tyr-1139, Tyr-1221, and Tyr-1222 of the amino acid sequence represented by UniProtKB:P04626-1. Example: UniProtKB:P04626-1, 23-1255, Tyr-1023/Tyr-1139/Tyr-1221/Tyr-1222, MOD:00048." [PRO:DNx, Reactome:R-HSA-8864084]
comment: Category=organism-modification.
synonym: "hERBB2/SigPep-/Phos:8" EXACT PRO-short-label [PRO:DNx]
synonym: "p-Y1023,Y1139,Y1221,Y1222-ERBB2" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-8864084]
synonym: "UniProtKB:P04626, 23-1255, Tyr-1023/Tyr-1139/Tyr-1221/Tyr-1222, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P04626-1, 23-1255, Tyr-1023/Tyr-1139/Tyr-1221/Tyr-1222, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8864084 "PR:000062031 located_in GO:0005886"
is_a: PR:P04626 ! receptor tyrosine-protein kinase erbB-2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens