[Term]
id: PR:000063580
name: mothers against decapentaplegic homolog 3 sequence variant R268C phosphorylated 1 (human)
def: "A mothers against decapentaplegic homolog 3 (human) that has a Cys residue at the position equivalent to Arg-268 of the amino acid sequence represented by UniProtKB:P84022-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-423 and Ser-425. Example: UniProtKB:P84022-1, Arg-268, CHEBI:29950|Ser-423/Ser-425, MOD:00046." [PRO:DNx, Reactome:R-HSA-3315075]
comment: Category=organism-modification.
synonym: "hSMAD3/var:R268C/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "p-S423,S425-SMAD3 R268C" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-3315075]
synonym: "UniProtKB:P84022, Arg-268, CHEBI:29950|Ser-423/Ser-425, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P84022-1, Arg-268, CHEBI:29950|Ser-423/Ser-425, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3315075 "PR:000063580 located_in GO:0005829"
is_a: PR:P84022 ! mothers against decapentaplegic homolog 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens