[Term]
id: PR:000064006
name: receptor tyrosine-protein kinase erbB-2, signal peptide removed phosphorylated 10 (human)
def: "A receptor tyrosine-protein kinase erbB-2 (human) that has had the signal peptide removed, that has been phosphorylated on the residue at the position equivalent to Tyr-877 of the amino acid sequence represented by UniProtKB:P04626-1, and that includes at least 1 additional phosphorylated tyrosine. Example: UniProtKB:P04626-1, 23-1255, Tyr-877, MOD:00048|MOD:00048." [PRO:DNx, Reactome:R-HSA-1810446]
comment: Category=organism-modification.
synonym: "hERBB2/SigPep-/Phos:10" EXACT PRO-short-label [PRO:DNx]
synonym: "p-Y,Y877-ERBB2" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1810446]
synonym: "UniProtKB:P04626, 23-1255, Tyr-877, MOD:00048|MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P04626-1, 23-1255, Tyr-877, MOD:00048|MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1810446 "PR:000064006 located_in GO:0005886"
is_a: PR:P04626 ! receptor tyrosine-protein kinase erbB-2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens