PRotein Ontology (PRO) Release 27.0 (25-Apr-2012) There are 28555 PRO terms 314 terms are in the 'family' category. 18274 terms are in the 'gene' category. 1471 terms are in the 'sequence' category. 6139 terms are in the 'modification' category. 125 terms are in the 'complex' category. 4 terms are in the 'organism-family' category. 868 terms are in the 'organism-gene' category. 518 terms are in the 'organism-sequence' category. 485 terms are in the 'organism-modification' category. 233 terms are in the 'organism-complex' category. 12 terms are in the 'union' category. 1648 terms have some kind of annotation, codifying the information from 1161 papers. 2410 connections to GO (840 PRO terms). 374 connections to MOD (327 PRO terms). 604 connections to Pfam (361 PRO terms). 338 connections to SO (317 PRO terms). 344 annotations of a phenotype (337 PRO terms). The ontology includes a subset of terms from other ontologies and resources that are used for logical definitions. _Current changes_ 1) Nearly 2200 additional terms have short labels applied. Short labels were added to many specific modified forms (of the type "XXX phophorylated 1"). 2) Over 60000 additional UniProtKB mappings have been added to the promapping files. The additional mapped accessions are predominantly from the model organisms rat, chicken, fruit fly, zebrafish, A. thaliana, S. Pombe, S. cerevisiae, C. elegans, and D. Discoideum, joining the previous mapped set from human, mouse, and E. coli. Many thanks to Paul Thomas for providing Panther data used to do the mapping! _Forthcoming changes_ 1) Continue to add shorthand labels to terms. 2) Continue to expand the set of mapped terms.