PRO_ID Object_term Object_syny Modifier Relation Ontology_ID Ontology_term Relative_to Interaction_with Evidence_source Evidence_code Taxon Inferred_from DB_ID Date Assigned_by Comment PR:000000002 E3 ubiquitin ligase SFC complex Skp1 subunit part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF028729 ISS PIRSF:PIRSF028729 PIRSF:PIRSF028729 20080301 PRO:CNA PR:000000002 E3 ubiquitin ligase SFC complex Skp1 subunit acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PIRSF:PIRSF028729 ISS PIRSF:PIRSF028729 PIRSF:PIRSF028729 20080301 PRO:CNA PR:000000003 HLH DNA-binding protein inhibitor bHLH clade D|bHLH class V|DNA-binding protein inhibitor ID|ID protein enables GO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF005808 ISS PIRSF:PIRSF005808 PIRSF:PIRSF005808 20150820 PRO:CNA PR:000000003 HLH DNA-binding protein inhibitor bHLH clade D|bHLH class V|DNA-binding protein inhibitor ID|ID protein acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF005808 ISS PIRSF:PIRSF005808 PIRSF:PIRSF005808 20080301 PRO:CNA PR:000000004 RING-box protein enables GO:0004842 ubiquitin-protein transferase activity PIRSF:PIRSF016237 ISS PIRSF:PIRSF016237 PIRSF:PIRSF016237 20080301 PRO:CNA PR:000000004 RING-box protein enables GO:0005515 protein binding PIRSF:PIRSF016237 ISS PIRSF:PIRSF016237 PIRSF:PIRSF016237 20080301 PRO:CNA PR:000000004 RING-box protein acts_upstream_of_or_within GO:0016567 protein ubiquitination PIRSF:PIRSF016237 ISS PIRSF:PIRSF016237 PIRSF:PIRSF016237 20080301 PRO:CNA PR:000000005 TGF-beta receptor type-2 TbetaR-II|TGF-beta receptor type II|TGF-beta type II receptor|TGFBR2|TGFR-2|transforming growth factor-beta receptor type II enables GO:0004672 protein kinase activity PIRSF:PIRSF037393 ISS PIRSF:PIRSF037393 PIRSF:PIRSF037393|UniProtKB:P37173|UniProtKB:Q62312 20080301 PRO:CNA PR:000000005 TGF-beta receptor type-2 TbetaR-II|TGF-beta receptor type II|TGF-beta type II receptor|TGFBR2|TGFR-2|transforming growth factor-beta receptor type II enables GO:0005515 protein binding PIRSF:PIRSF037393 ISS PIRSF:PIRSF037393 PIRSF:PIRSF037393|UniProtKB:P37173|UniProtKB:Q62312 20080301 PRO:CNA PR:000000005 TGF-beta receptor type-2 TbetaR-II|TGF-beta receptor type II|TGF-beta type II receptor|TGFBR2|TGFR-2|transforming growth factor-beta receptor type II acts_upstream_of_or_within GO:0006468 protein phosphorylation PIRSF:PIRSF037393 ISS PIRSF:PIRSF037393 PIRSF:PIRSF037393|UniProtKB:P37173|UniProtKB:Q62312 20080301 PRO:CNA PR:000000005 TGF-beta receptor type-2 TbetaR-II|TGF-beta receptor type II|TGF-beta type II receptor|TGFBR2|TGFR-2|transforming growth factor-beta receptor type II acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PIRSF:PIRSF037393 ISS PIRSF:PIRSF037393 PIRSF:PIRSF037393|UniProtKB:P37173|UniProtKB:Q62312 20080301 PRO:CNA PR:000000005 TGF-beta receptor type-2 TbetaR-II|TGF-beta receptor type II|TGF-beta type II receptor|TGFBR2|TGFR-2|transforming growth factor-beta receptor type II acts_upstream_of_or_within GO:0042127 regulation of cell population proliferation PIRSF:PIRSF037393 ISS PIRSF:PIRSF037393 PIRSF:PIRSF037393|UniProtKB:P37173|UniProtKB:Q62312 20080301 PRO:CNA PR:000000006 TGF-beta superfamily receptor type-1 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I (PTHR23255:SF15) enables GO:0005025 transforming growth factor beta receptor activity, type I PIRSF:PIRSF037391 ISS PIRSF:PIRSF037391 PIRSF:PIRSF037391 20080301 PRO:CNA PR:000000006 TGF-beta superfamily receptor type-1 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I (PTHR23255:SF15) enables GO:0019838 growth factor binding PR:000000046 PANTHER:PTHR23255:SF14|PIRSF:PIRSF037391 ISS PANTHER:PTHR23255:SF14|PIRSF:PIRSF037391 PANTHER:PTHR23255:SF14|PIRSF:PIRSF037391 20080922 PRO:CNA PR:000000006 TGF-beta superfamily receptor type-1 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I (PTHR23255:SF15) acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PIRSF:PIRSF037391 ISS PIRSF:PIRSF037391 PIRSF:PIRSF037391 20080301 PRO:CNA PR:000000007 TGF-beta superfamily receptor type-2 with activin receptor domain enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PIRSF:PIRSF000627 ISS PIRSF:PIRSF000627 PIRSF:PIRSF000627 20080301 PRO:CNA PR:000000007 TGF-beta superfamily receptor type-2 with activin receptor domain enables GO:0005515 protein binding PIRSF:PIRSF000627 ISS PIRSF:PIRSF000627 PIRSF:PIRSF000627 20080301 PRO:CNA PR:000000007 TGF-beta superfamily receptor type-2 with activin receptor domain acts_upstream_of_or_within GO:0006468 protein phosphorylation PIRSF:PIRSF000627 ISS PIRSF:PIRSF000627 PIRSF:PIRSF000627 20080301 PRO:CNA PR:000000007 TGF-beta superfamily receptor type-2 with activin receptor domain acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PIRSF:PIRSF000627 ISS PIRSF:PIRSF000627 PIRSF:PIRSF000627 20080301 PRO:CNA PR:000000009 anti-Muellerian hormone type-2 receptor AMH type II receptor|AMHR|AMHR2|anti-Muellerian hormone type II receptor|MIS type II receptor|MISR2|MISRII|MRII acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PIRSF:PIRSF037392 ISS PIRSF:PIRSF037392 PIRSF:PIRSF037392|UniProtKB:Q16671|UniProtKB:Q8K592 20150820 PRO:CNA PR:000000009 anti-Muellerian hormone type-2 receptor AMH type II receptor|AMHR|AMHR2|anti-Muellerian hormone type II receptor|MIS type II receptor|MISR2|MISRII|MRII acts_upstream_of_or_within GO:0007548 sex differentiation PIRSF:PIRSF037392 ISS PIRSF:PIRSF037392 PIRSF:PIRSF037392|UniProtKB:Q16671|UniProtKB:Q8K592 20080301 PRO:CNA PR:000000010 chordin CHRD|UNQ217/PRO243 enables GO:0005515 protein binding PIRSF:PIRSF002496 ISS PIRSF:PIRSF002496 PIRSF:PIRSF002496|UniProtKB:Q9H2X0|UniProtKB:Q9Z0E2 20080301 PRO:CNA PR:000000010 chordin CHRD|UNQ217/PRO243 enables GO:0008201 heparin binding PIRSF:PIRSF002496 ISS PIRSF:PIRSF002496 PIRSF:PIRSF002496|UniProtKB:Q9H2X0|UniProtKB:Q9Z0E2 20080301 PRO:CNA PR:000000010 chordin CHRD|UNQ217/PRO243 enables GO:0045545 syndecan binding PIRSF:PIRSF002496 ISS PIRSF:PIRSF002496 PIRSF:PIRSF002496|UniProtKB:Q9H2X0|UniProtKB:Q9Z0E2 20080301 PRO:CNA PR:000000010 chordin CHRD|UNQ217/PRO243 acts_upstream_of_or_within GO:0030510 regulation of BMP signaling pathway PIRSF:PIRSF002496 ISS PIRSF:PIRSF002496 PIRSF:PIRSF002496|UniProtKB:Q9H2X0|UniProtKB:Q9Z0E2 20080301 PRO:CNA PR:000000011 class 1 small leucine-rich proteoglycan enables GO:0005201 extracellular matrix structural constituent PIRSF:PIRSF002490 ISS PIRSF:PIRSF002490 PIRSF:PIRSF002490 20080301 PRO:CNA PR:000000013 cullin part_of GO:0031461 cullin-RING ubiquitin ligase complex PIRSF:PIRSF017874 ISS PIRSF:PIRSF017874 PIRSF:PIRSF017874 20080301 PRO:CNA PR:000000014 cyclin-dependent kinase inhibitor enables GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PIRSF:PIRSF036346 ISS PIRSF:PIRSF036346 PIRSF:PIRSF036346 20080301 PRO:CNA PR:000000014 cyclin-dependent kinase inhibitor acts_upstream_of_or_within GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity PIRSF:PIRSF036346 ISS PIRSF:PIRSF036346 PIRSF:PIRSF036346 20080301 PRO:CNA PR:000000014 cyclin-dependent kinase inhibitor acts_upstream_of_or_within GO:0051726 regulation of cell cycle PIRSF:PIRSF036346 ISS PIRSF:PIRSF036346 PIRSF:PIRSF036346 20080301 PRO:CNA PR:000000014 cyclin-dependent kinase inhibitor acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PIRSF:PIRSF036346 ISS PIRSF:PIRSF036346 PIRSF:PIRSF036346 20080301 PRO:CNA PR:000000015 follistatin activin-binding protein|FS|FST acts_upstream_of_or_within GO:0032926 negative regulation of activin receptor signaling pathway PIRSF:PIRSF002278 ISS PIRSF:PIRSF002278 PIRSF:PIRSF002278|UniProtKB:P19883|UniProtKB:P47931 20080301 PRO:CNA PR:000000016 HECT domain-containing E3 ubiquitin-protein ligase with WW domains enables GO:0004842 ubiquitin-protein transferase activity PIRSF:PIRSF001569 ISS PIRSF:PIRSF001569 PIRSF:PIRSF001569 20080301 PRO:CNA PR:000000017 interferon gamma IFN-gamma|IFNG|immune interferon acts_upstream_of_or_within GO:0006955 immune response PIRSF:PIRSF001936 ISS PIRSF:PIRSF001936 PIRSF:PIRSF001936|UniProtKB:P01579|UniProtKB:P01580 20080301 PRO:CNA PR:000000017 interferon gamma IFN-gamma|IFNG|immune interferon acts_upstream_of_or_within GO:0032722 positive regulation of chemokine production PIRSF:PIRSF001936 ISS PIRSF:PIRSF001936 PIRSF:PIRSF001936|UniProtKB:P01579|UniProtKB:P01580 20080301 PRO:CNA PR:000000018 latent TGF-beta-binding protein enables GO:0019838 growth factor binding PR:000000046 PIRSF:PIRSF037569 ISS PIRSF:PIRSF037569 PIRSF:PIRSF037569 20080301 PRO:CNA PR:000000018 latent TGF-beta-binding protein acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PIRSF:PIRSF037569 ISS PIRSF:PIRSF037569 PIRSF:PIRSF037569 20080301 PRO:CNA PR:000000019 mitogen-activated protein kinase kinase-related transforming protein|MAPK enables GO:0004672 protein kinase activity PIRSF:PIRSF501110 ISS PIRSF:PIRSF501110 PIRSF:PIRSF501110 20090601 PRO:CNA PR:000000019 mitogen-activated protein kinase kinase-related transforming protein|MAPK acts_upstream_of_or_within GO:0006468 protein phosphorylation PIRSF:PIRSF501110 ISS PIRSF:PIRSF501110 PIRSF:PIRSF501110 20090601 PRO:CNA PR:000000020 Myc protein bHLH clade B|bHLH class III enables GO:0003677 DNA binding PIRSF:PIRSF001705 ISS PIRSF:PIRSF001705 PIRSF:PIRSF001705 20080301 PRO:CNA PR:000000020 Myc protein bHLH clade B|bHLH class III enables GO:0005515 protein binding PIRSF:PIRSF001705 ISS PIRSF:PIRSF001705 PIRSF:PIRSF001705 20080301 PRO:CNA PR:000000020 Myc protein bHLH clade B|bHLH class III acts_upstream_of_or_within GO:0042127 regulation of cell population proliferation PIRSF:PIRSF001705 ISS PIRSF:PIRSF001705 PIRSF:PIRSF001705 20080301 PRO:CNA PR:000000021 noggin NOG acts_upstream_of_or_within GO:0007275 multicellular organism development PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 ISS PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 20080301 PRO:CNA PR:000000021 noggin NOG acts_upstream_of_or_within GO:0030509 BMP signaling pathway PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 ISS PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 20080301 PRO:CNA PR:000000021 noggin NOG acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 ISS PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 PANTHER:PTHR10494:SF2|PIRSF:PIRSF008129|UniProtKB:P97466|UniProtKB:Q13253 20080301 PRO:CNA PR:000000022 ptx homeobox protein enables GO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF000563 ISS PIRSF:PIRSF000563 PIRSF:PIRSF000563 20080301 PRO:CNA PR:000000022 ptx homeobox protein acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF000563 ISS PIRSF:PIRSF000563 PIRSF:PIRSF000563 20080301 PRO:CNA PR:000000022 ptx homeobox protein acts_upstream_of_or_within GO:0007275 multicellular organism development PIRSF:PIRSF000563 ISS PIRSF:PIRSF000563 PIRSF:PIRSF000563 20080301 PRO:CNA PR:000000023 retinoblastoma-like protein enables GO:0005515 protein binding PIRSF:PIRSF037408 ISS PIRSF:PIRSF037408 PIRSF:PIRSF037408 20080301 PRO:CNA PR:000000023 retinoblastoma-like protein acts_upstream_of_or_within GO:0051726 regulation of cell cycle PIRSF:PIRSF037408 ISS PIRSF:PIRSF037408 PIRSF:PIRSF037408 20080301 PRO:CNA PR:000000024 Rho-associated protein kinase RHO-ASSOCIATED, COILED-COIL CONTAINING PROTEIN KINASE (PTHR22988:SF3) enables GO:0004672 protein kinase activity PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 ISS PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 20080301 PRO:CNA PR:000000024 Rho-associated protein kinase RHO-ASSOCIATED, COILED-COIL CONTAINING PROTEIN KINASE (PTHR22988:SF3) enables GO:0004674 protein serine/threonine kinase activity PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 ISS PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 20080301 PRO:CNA PR:000000024 Rho-associated protein kinase RHO-ASSOCIATED, COILED-COIL CONTAINING PROTEIN KINASE (PTHR22988:SF3) acts_upstream_of_or_within GO:0006468 protein phosphorylation PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 ISS PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 20080301 PRO:CNA PR:000000024 Rho-associated protein kinase RHO-ASSOCIATED, COILED-COIL CONTAINING PROTEIN KINASE (PTHR22988:SF3) acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 ISS PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 PANTHER:PTHR22988:SF3|PIRSF:PIRSF037568 20080301 PRO:CNA PR:000000025 ribosomal protein S6 kinase beta enables GO:0004672 protein kinase activity PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 ISS PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 20080301 PRO:CNA PR:000000025 ribosomal protein S6 kinase beta enables GO:0004711 ribosomal protein S6 kinase activity PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 ISS PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 20080301 PRO:CNA PR:000000025 ribosomal protein S6 kinase beta acts_upstream_of_or_within GO:0006468 protein phosphorylation PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 ISS PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 PANTHER:PTHR24351:SF83|PIRSF:PIRSF000605 20080301 PRO:CNA PR:000000026 sara-type zinc finger FYVE domain-containing protein acts_upstream_of_or_within GO:0008104 protein localization PIRSF:PIRSF037289 ISS PIRSF:PIRSF037289 PIRSF:PIRSF037289 20080301 PRO:CNA PR:000000027 smad protein enables GO:0005515 protein binding PIRSF:PIRSF037286 ISS PIRSF:PIRSF037286 PIRSF:PIRSF037286 20080301 PRO:CNA PR:000000027 smad protein acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF037286 ISS PIRSF:PIRSF037286 PIRSF:PIRSF037286 20080301 PRO:CNA PR:000000027 smad protein acts_upstream_of_or_within GO:0007165 signal transduction PIRSF:PIRSF037286 ISS PIRSF:PIRSF037286 PIRSF:PIRSF037286 20080301 PRO:CNA PR:000000029 thrombospondin subgroup A enables GO:0004866 endopeptidase inhibitor activity PIRSF:PIRSF002478 ISS PIRSF:PIRSF002478 PIRSF:PIRSF002478 20080301 PRO:CNA PR:000000029 thrombospondin subgroup A enables GO:0008201 heparin binding PIRSF:PIRSF002478 ISS PIRSF:PIRSF002478 PIRSF:PIRSF002478 20080301 PRO:CNA PR:000000029 thrombospondin subgroup A acts_upstream_of_or_within GO:0016525 negative regulation of angiogenesis PIRSF:PIRSF002478 ISS PIRSF:PIRSF002478 PIRSF:PIRSF002478 20080301 PRO:CNA PR:000000030 thrombospondin subgroup B enables GO:0008201 heparin binding PIRSF:PIRSF002479 ISS PIRSF:PIRSF002479 PIRSF:PIRSF002479 20080301 PRO:CNA PR:000000031 transcription adapter with TAZ, KIX and bromo-domains fam:CBP-p300 enables GO:0004402 histone acetyltransferase activity PANTHER:PTHR13808|PIRSF:PIRSF036333 ISS PANTHER:PTHR13808|PIRSF:PIRSF036333 PANTHER:PTHR13808|PIRSF:PIRSF036333 20080301 PRO:CNA PR:000000032 transcription factor Sp enables GO:0003677 DNA binding PIRSF:PIRSF037570 ISS PIRSF:PIRSF037570 PIRSF:PIRSF037570 20080301 PRO:CNA PR:000000032 transcription factor Sp enables GO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF037570 ISS PIRSF:PIRSF037570 PIRSF:PIRSF037570 20080301 PRO:CNA PR:000000032 transcription factor Sp acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF037570 ISS PIRSF:PIRSF037570 PIRSF:PIRSF037570 20080301 PRO:CNA PR:000000033 tumor necrosis factor, TNF-like enables GO:0005125 cytokine activity PIRSF:PIRSF001873 ISS PIRSF:PIRSF001873 PIRSF:PIRSF001873 20080301 PRO:CNA PR:000000033 tumor necrosis factor, TNF-like acts_upstream_of_or_within GO:0006915 apoptotic process PIRSF:PIRSF001873 ISS PIRSF:PIRSF001873 PIRSF:PIRSF001873 20080301 PRO:CNA PR:000000033 tumor necrosis factor, TNF-like acts_upstream_of_or_within GO:0007165 signal transduction PIRSF:PIRSF001873 ISS PIRSF:PIRSF001873 PIRSF:PIRSF001873 20080301 PRO:CNA PR:000000034 bone morphogenetic protein enables GO:0005102 signaling receptor binding PIRSF:PIRSF037272 ISS PIRSF:PIRSF037272 PIRSF:PIRSF037272 20080301 PRO:CNA PR:000000034 bone morphogenetic protein enables GO:0005125 cytokine activity PIRSF:PIRSF037272 ISS PIRSF:PIRSF037272 PIRSF:PIRSF037272 20080301 PRO:CNA PR:000000034 bone morphogenetic protein enables GO:0008083 growth factor activity PIRSF:PIRSF037272 ISS PIRSF:PIRSF037272 PIRSF:PIRSF037272 20080301 PRO:CNA PR:000000034 bone morphogenetic protein enables GO:0042803 protein homodimerization activity PIRSF:PIRSF037272 ISS PIRSF:PIRSF037272 PIRSF:PIRSF037272 20080301 PRO:CNA PR:000000037 BMP receptor type-2 BMP type II receptor|BMP type-2 receptor|BMPR-2|BMPR-II|BMPR2|bone morphogenetic protein receptor type II|BRK-3|PPH1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PIRSF:PIRSF500434 ISS PIRSF:PIRSF500434 PIRSF:PIRSF500434|UniProtKB:O35607|UniProtKB:Q13873 20080301 PRO:CNA PR:000000038 BMP receptor-regulated smad protein R-SMAD(BMP) acts_upstream_of_or_within GO:0030509 BMP signaling pathway PANTHER:PTHR13703:SF19|PIRSF:PIRSF500500 ISS PANTHER:PTHR13703:SF19|PIRSF:PIRSF500500 PANTHER:PTHR13703:SF19|PIRSF:PIRSF500500 20080301 PRO:CNA PR:000000039 DNA-binding protein inhibitor ID-1 BHLHB24|bHLHb24|class B basic helix-loop-helix protein 24|ID|Id-1|ID1|Idb1|inhibitor of differentiation 1|inhibitor of DNA binding 1 enables GO:0046983 protein dimerization activity PANTHER:PTHR11723:SF4|PIRSF:PIRSF500477 ISS PANTHER:PTHR11723:SF4|PIRSF:PIRSF500477 PANTHER:PTHR11723:SF4|PIRSF:PIRSF500477|UniProtKB:P20067|UniProtKB:P41134 20080301 PRO:CNA PR:000000040 DNA-binding protein inhibitor ID-2 BHLHB26|bHLHb26|class B basic helix-loop-helix protein 26|Id-2|ID2|Idb2|inhibitor of differentiation 2|inhibitor of DNA binding 2 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500478 ISS PIRSF:PIRSF500478|UniProtKB:P41136|UniProtKB:Q02363|UniProtKB:Q545T4 PIRSF:PIRSF500478|UniProtKB:P41136|UniProtKB:Q02363|UniProtKB:Q545T4 20080301 PRO:CNA PR:000000041 DNA-binding protein inhibitor ID-3 1R21|BHLHB25|bHLHb25|class B basic helix-loop-helix protein 25|HEIR1|helix-loop-helix protein HEIR-1|Hlh462|Id-3|ID-like protein inhibitor HLH 1R21|ID-like protein inhibitor HLH 462|ID3|Idb3|inhibitor of differentiation 3|inhibitor of DNA binding 3 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500479 ISS PIRSF:PIRSF500479|UniProtKB:P41133|UniProtKB:Q02535|UniProtKB:Q545W1 PIRSF:PIRSF500479|UniProtKB:P41133|UniProtKB:Q02535|UniProtKB:Q545W1 20080301 PRO:CNA PR:000000042 DNA-binding protein inhibitor ID-4 BHLHB27|bHLHb27|class B basic helix-loop-helix protein 27|Id-4|ID4|Idb4|inhibitor of differentiation 4|inhibitor of DNA binding 4 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PIRSF:PIRSF500478 ISS PIRSF:PIRSF500478|UniProtKB:P41139|UniProtKB:P47928|UniProtKB:Q544D2 PIRSF:PIRSF500478|UniProtKB:P41139|UniProtKB:P47928|UniProtKB:Q544D2 20080301 PRO:CNA PR:000000043 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein transferase RBX1|protein ZYP|RBX1|rbx1|regulator of cullins 1|RING finger protein 75|RING-box protein 1|RNF75|ROC1 part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724 ISS PIRSF:PIRSF500724|UniProtKB:P62877|UniProtKB:P62878 PIRSF:PIRSF500724|UniProtKB:P62877|UniProtKB:P62878 20080301 PRO:CNA PR:000000043 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein transferase RBX1|protein ZYP|RBX1|rbx1|regulator of cullins 1|RING finger protein 75|RING-box protein 1|RNF75|ROC1 acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724 ISS PIRSF:PIRSF500724|UniProtKB:P62877|UniProtKB:P62878 PIRSF:PIRSF500724|UniProtKB:P62877|UniProtKB:P62878 20080301 PRO:CNA PR:000000044 RING-box protein 2 CKBBP1|CKII beta-binding protein 1|RBX2|rbx2|regulator of cullins 2|RING finger protein 7|RNF7|ROC2|SAG|sensitive to apoptosis gene protein part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500725 ISS PIRSF:PIRSF500725|UniProtKB:Q9UBF6|UniProtKB:Q9WTZ1 PIRSF:PIRSF500725|UniProtKB:Q9UBF6|UniProtKB:Q9WTZ1 20080301 PRO:CNA PR:000000044 RING-box protein 2 CKBBP1|CKII beta-binding protein 1|RBX2|rbx2|regulator of cullins 2|RING finger protein 7|RNF7|ROC2|SAG|sensitive to apoptosis gene protein acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500725 ISS PIRSF:PIRSF500725|UniProtKB:Q9UBF6|UniProtKB:Q9WTZ1 PIRSF:PIRSF500725|UniProtKB:Q9UBF6|UniProtKB:Q9WTZ1 20080301 PRO:CNA PR:000000046 TGF-beta transforming growth factor beta enables GO:0005160 transforming growth factor beta receptor binding PIRSF:PIRSF001787 ISS PIRSF:PIRSF001787 PIRSF:PIRSF001787 20080301 PRO:CNA PR:000000046 TGF-beta transforming growth factor beta enables GO:0008083 growth factor activity PIRSF:PIRSF001787 ISS PIRSF:PIRSF001787 PIRSF:PIRSF001787 20080301 PRO:CNA PR:000000046 TGF-beta transforming growth factor beta enables GO:0042803 protein homodimerization activity PIRSF:PIRSF001787 ISS PIRSF:PIRSF001787 PIRSF:PIRSF001787 20080301 PRO:CNA PR:000000046 TGF-beta transforming growth factor beta acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PIRSF:PIRSF001787 ISS PIRSF:PIRSF001787 PIRSF:PIRSF001787 20080301 PRO:CNA PR:000000046 TGF-beta transforming growth factor beta acts_upstream_of_or_within GO:0042127 regulation of cell population proliferation PIRSF:PIRSF001787 ISS PIRSF:PIRSF001787 PIRSF:PIRSF001787 20080301 PRO:CNA PR:000000050 TGF-beta receptor type-2 sequence variant L308P (human) hTGFBR2/var:L308P|TGF-beta receptor type-2 sequence variant 1 (human)|UniProtKB:P37173-1, Leu-308, CHEBI:50342 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022351 20080301 PRO:CNA PR:000000050 TGF-beta receptor type-2 sequence variant L308P (human) hTGFBR2/var:L308P|TGF-beta receptor type-2 sequence variant 1 (human)|UniProtKB:P37173-1, Leu-308, CHEBI:50342 NOT enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022351 20080301 PRO:CNA PR:000000051 TGF-beta receptor type-2 sequence variant R460H (human) hTGFBR2/var:R460H|TGF-beta receptor type-2 sequence variant 10 (human)|UniProtKB:P37173-1, Arg-460, CHEBI:29979 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029761 20080301 PRO:CNA PR:000000052 TGF-beta receptor type-2 sequence variant R460C (human) hTGFBR2/var:R460C|TGF-beta receptor type-2 sequence variant 11 (human)|UniProtKB:P37173-1, Arg-460, CHEBI:29950 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029760 20080301 PRO:CNA PR:000000053 TGF-beta receptor type-2 sequence variant E526Q (human) hTGFBR2/var:E526Q|TGF-beta receptor type-2 sequence variant 12 (human)|UniProtKB:P37173-1, Glu-526, CHEBI:30011 associated_with_disease_progression DOID:3748 esophagus squamous cell carcinoma PMID:10789724 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015816 20080301 PRO:CNA PR:000000053 TGF-beta receptor type-2 sequence variant E526Q (human) hTGFBR2/var:E526Q|TGF-beta receptor type-2 sequence variant 12 (human)|UniProtKB:P37173-1, Glu-526, CHEBI:30011 NOT enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:10789724 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015816 20080301 PRO:CNA PR:000000054 TGF-beta receptor type-2 sequence variant R528C (human) hTGFBR2/var:R528C|TGF-beta receptor type-2 sequence variant 13 (human)|UniProtKB:P37173-1, Arg-528, CHEBI:29950 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022360 20080301 PRO:CNA PR:000000055 TGF-beta receptor type-2 sequence variant R528H (human) hTGFBR2/var:R528H|TGF-beta receptor type-2 sequence variant 14 (human)|UniProtKB:P37173-1, Arg-528, CHEBI:29979 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022361 20080301 PRO:CNA PR:000000056 TGF-beta receptor type-2 sequence variant R537C (human) hTGFBR2/var:R537C|TGF-beta receptor type-2 sequence variant 15 (human)|UniProtKB:P37173-1, Arg-537, CHEBI:29950 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022362 20080301 PRO:CNA PR:000000056 TGF-beta receptor type-2 sequence variant R537C (human) hTGFBR2/var:R537C|TGF-beta receptor type-2 sequence variant 15 (human)|UniProtKB:P37173-1, Arg-537, CHEBI:29950 NOT enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022362 20080301 PRO:CNA PR:000000057 TGF-beta receptor type-2 sequence variant G357W (human) hTGFBR2/var:G357W|TGF-beta receptor type-2 sequence variant 16 (human)|UniProtKB:P37173-1, Gly-357, CHEBI:29954 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022354 20080301 PRO:CNA PR:000000058 TGF-beta receptor type-2 sequence variant T315M (human) hTGFBR2/var:T315M|TGF-beta receptor type-2 sequence variant 2 (human)|UniProtKB:P37173-1, Thr-315, CHEBI:16044 associated_with_disease_progression DOID:3883 Lynch syndrome PMID:9590282 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008156 20080301 PRO:CNA PR:000000058 TGF-beta receptor type-2 sequence variant T315M (human) hTGFBR2/var:T315M|TGF-beta receptor type-2 sequence variant 2 (human)|UniProtKB:P37173-1, Thr-315, CHEBI:16044 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:9590282 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008156 20080301 PRO:CNA PR:000000059 TGF-beta receptor type-2 sequence variant Y336N (human) hTGFBR2/var:Y336N|TGF-beta receptor type-2 sequence variant 3 (human)|UniProtKB:P37173-1, Tyr-336, CHEBI:50347 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022352 20080301 PRO:CNA PR:000000060 TGF-beta receptor type-2 sequence variant A355P (human) hTGFBR2/var:A355P|TGF-beta receptor type-2 sequence variant 4 (human)|UniProtKB:P37173-1, Ala-355, CHEBI:50342 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022353 20080301 PRO:CNA PR:000000060 TGF-beta receptor type-2 sequence variant A355P (human) hTGFBR2/var:A355P|TGF-beta receptor type-2 sequence variant 4 (human)|UniProtKB:P37173-1, Ala-355, CHEBI:50342 located_in GO:0016020 membrane PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022353 20080301 PRO:CNA PR:000000060 TGF-beta receptor type-2 sequence variant A355P (human) hTGFBR2/var:A355P|TGF-beta receptor type-2 sequence variant 4 (human)|UniProtKB:P37173-1, Ala-355, CHEBI:50342 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022353 20080301 PRO:CNA PR:000000061 TGF-beta receptor type-2 sequence variant V387M (human) hTGFBR2/var:V387M|TGF-beta receptor type-2 sequence variant 5 (human)|UniProtKB:P37173-1, Val-387, CHEBI:16044 located_in GO:0016020 membrane PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022355 20080301 PRO:CNA PR:000000061 TGF-beta receptor type-2 sequence variant V387M (human) hTGFBR2/var:V387M|TGF-beta receptor type-2 sequence variant 5 (human)|UniProtKB:P37173-1, Val-387, CHEBI:16044 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022355 20080301 PRO:CNA PR:000000061 TGF-beta receptor type-2 sequence variant V387M (human) hTGFBR2/var:V387M|TGF-beta receptor type-2 sequence variant 5 (human)|UniProtKB:P37173-1, Val-387, CHEBI:16044 decreased enables GO:0005026 transforming growth factor beta receptor activity, type II PR:000000409 PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022355 20080301 PRO:CNA PR:000000062 TGF-beta receptor type-2 sequence variant N435S (human) hTGFBR2/var:N435S|TGF-beta receptor type-2 sequence variant 6 (human)|UniProtKB:P37173-1, Asn-435, CHEBI:29999 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022356 20080301 PRO:CNA PR:000000062 TGF-beta receptor type-2 sequence variant N435S (human) hTGFBR2/var:N435S|TGF-beta receptor type-2 sequence variant 6 (human)|UniProtKB:P37173-1, Asn-435, CHEBI:29999 decreased enables GO:0005026 transforming growth factor beta receptor activity, type II PR:000000409 PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022356 20080301 PRO:CNA PR:000000063 TGF-beta receptor type-2 sequence variant V447A (human) hTGFBR2/var:V447A|TGF-beta receptor type-2 sequence variant 7 (human)|UniProtKB:P37173-1, Val-447, CHEBI:46217 located_in GO:0016020 membrane PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022357 20080301 PRO:CNA PR:000000063 TGF-beta receptor type-2 sequence variant V447A (human) hTGFBR2/var:V447A|TGF-beta receptor type-2 sequence variant 7 (human)|UniProtKB:P37173-1, Val-447, CHEBI:46217 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022357 20080301 PRO:CNA PR:000000063 TGF-beta receptor type-2 sequence variant V447A (human) hTGFBR2/var:V447A|TGF-beta receptor type-2 sequence variant 7 (human)|UniProtKB:P37173-1, Val-447, CHEBI:46217 decreased enables GO:0005026 transforming growth factor beta receptor activity, type II PR:000000409 PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022357 20080301 PRO:CNA PR:000000064 TGF-beta receptor type-2 sequence variant S449F (human) hTGFBR2/var:S449F|TGF-beta receptor type-2 sequence variant 8 (human)|UniProtKB:P37173-1, Ser-449, CHEBI:29997 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022358 20080301 PRO:CNA PR:000000064 TGF-beta receptor type-2 sequence variant S449F (human) hTGFBR2/var:S449F|TGF-beta receptor type-2 sequence variant 8 (human)|UniProtKB:P37173-1, Ser-449, CHEBI:29997 NOT enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:15235604 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022358 20080301 PRO:CNA PR:000000065 TGF-beta receptor type-2 sequence variant L452M (human) hTGFBR2/var:L452M|TGF-beta receptor type-2 sequence variant 9 (human)|UniProtKB:P37173-1, Leu-452, CHEBI:16044 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022359 20080301 PRO:CNA PR:000000065 TGF-beta receptor type-2 sequence variant L452M (human) hTGFBR2/var:L452M|TGF-beta receptor type-2 sequence variant 9 (human)|UniProtKB:P37173-1, Leu-452, CHEBI:16044 decreased enables GO:0005026 transforming growth factor beta receptor activity, type II PR:000000409 PMID:11212236 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022359 20080301 PRO:CNA PR:000000066 TGF-beta receptor-regulated smad protein R-SMAD(TGFB) acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PIRSF:PIRSF500455 ISS PIRSF:PIRSF500455 PIRSF:PIRSF500455 20080301 PRO:CNA PR:000000066 TGF-beta receptor-regulated smad protein R-SMAD(TGFB) acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PIRSF:PIRSF500455 ISS PIRSF:PIRSF500455 PIRSF:PIRSF500455 20080301 PRO:CNA PR:000000070 activin receptor type-2A activin receptor type IIA|ACTR-IIA|ACTRIIA|ACVR2|ACVR2A enables GO:0048185 activin binding PIRSF:PIRSF500457 ISS PIRSF:PIRSF500457|UniProtKB:P27037|UniProtKB:P27038|UniProtKB:Q8BRV4 PIRSF:PIRSF500457|UniProtKB:P27037|UniProtKB:P27038|UniProtKB:Q8BRV4 20080301 PRO:CNA PR:000000070 activin receptor type-2A activin receptor type IIA|ACTR-IIA|ACTRIIA|ACVR2|ACVR2A acts_upstream_of_or_within GO:0032924 activin receptor signaling pathway PIRSF:PIRSF500457 ISS PIRSF:PIRSF500457|UniProtKB:P27037|UniProtKB:P27038|UniProtKB:Q8BRV4 PIRSF:PIRSF500457|UniProtKB:P27037|UniProtKB:P27038|UniProtKB:Q8BRV4 20080301 PRO:CNA PR:000000071 activin receptor type-2B activin receptor type IIB|ACTR-IIB|ACVR2B enables GO:0048185 activin binding PIRSF:PIRSF500456 ISS PIRSF:PIRSF500456|UniProtKB:P27040|UniProtKB:Q13705|UniProtKB:Q3KQI1 PIRSF:PIRSF500456|UniProtKB:P27040|UniProtKB:Q13705|UniProtKB:Q3KQI1 20080301 PRO:CNA PR:000000071 activin receptor type-2B activin receptor type IIB|ACTR-IIB|ACVR2B acts_upstream_of_or_within GO:0032924 activin receptor signaling pathway PIRSF:PIRSF500456 ISS PIRSF:PIRSF500456|UniProtKB:P27040|UniProtKB:Q13705|UniProtKB:Q3KQI1 PIRSF:PIRSF500456|UniProtKB:P27040|UniProtKB:Q13705|UniProtKB:Q3KQI1 20080301 PRO:CNA PR:000000072 activin/inhibin beta subunit enables GO:0005102 signaling receptor binding PIRSF:PIRSF037268 ISS PIRSF:PIRSF037268 PIRSF:PIRSF037268 20080301 PRO:CNA PR:000000073 Muellerian-inhibiting factor AMH|anti-Muellerian hormone|MIF|MIS|Muellerian-inhibiting substance enables GO:0005102 signaling receptor binding PIRSF:PIRSF037270 ISS PIRSF:PIRSF037270 PIRSF:PIRSF037270|UniProtKB:P03971|UniProtKB:P27106 20080301 PRO:CNA PR:000000073 Muellerian-inhibiting factor AMH|anti-Muellerian hormone|MIF|MIS|Muellerian-inhibiting substance enables GO:0005179 hormone activity PIRSF:PIRSF037270 ISS PIRSF:PIRSF037270 PIRSF:PIRSF037270|UniProtKB:P03971|UniProtKB:P27106 20080301 PRO:CNA PR:000000073 Muellerian-inhibiting factor AMH|anti-Muellerian hormone|MIF|MIS|Muellerian-inhibiting substance acts_upstream_of_or_within GO:0007548 sex differentiation PIRSF:PIRSF037270 ISS PIRSF:PIRSF037270 PIRSF:PIRSF037270|UniProtKB:P03971|UniProtKB:P27106 20080301 PRO:CNA PR:000000073 Muellerian-inhibiting factor AMH|anti-Muellerian hormone|MIF|MIS|Muellerian-inhibiting substance acts_upstream_of_or_within GO:0008406 gonad development PIRSF:PIRSF037270 ISS PIRSF:PIRSF037270 PIRSF:PIRSF037270|UniProtKB:P03971|UniProtKB:P27106 20080301 PRO:CNA PR:000000075 anti-Muellerian hormone type-2 receptor sequence variant R54C (human) anti-Muellerian hormone type-2 receptor sequence variant 1 (human)|hAMHR2/var:R54C|UniProtKB:Q16671-1, Arg-54, CHEBI:29950 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015525 20080301 PRO:CNA PR:000000076 anti-Muellerian hormone type-2 receptor sequence variant G142V (human) anti-Muellerian hormone type-2 receptor sequence variant 2 (human)|hAMHR2/var:G142V|UniProtKB:Q16671-1, Gly-142, CHEBI:30015 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015526 20080301 PRO:CNA PR:000000077 anti-Muellerian hormone type-2 receptor sequence variant H282Q (human) anti-Muellerian hormone type-2 receptor sequence variant 3 (human)|hAMHR2/var:H282Q|UniProtKB:Q16671-1, His-282, CHEBI:30011 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015527 20080301 PRO:CNA PR:000000078 anti-Muellerian hormone type-2 receptor sequence variant R406Q (human) anti-Muellerian hormone type-2 receptor sequence variant 4 (human)|hAMHR2/var:R406Q|UniProtKB:Q16671-1, Arg-406, CHEBI:30011 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:11549681 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015528 20080301 PRO:CNA PR:000000079 anti-Muellerian hormone type-2 receptor sequence variant D426G (human) anti-Muellerian hormone type-2 receptor sequence variant 5 (human)|hAMHR2/var:D426G|UniProtKB:Q16671-1, Asp-426, CHEBI:29947 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015529 20080301 PRO:CNA PR:000000080 anti-Muellerian hormone type-2 receptor sequence variant V458A (human) anti-Muellerian hormone type-2 receptor sequence variant 6 (human)|hAMHR2/var:V458A|UniProtKB:Q16671-1, Val-458, CHEBI:46217 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015530 20080301 PRO:CNA PR:000000081 anti-Muellerian hormone type-2 receptor sequence variant D491H (human) anti-Muellerian hormone type-2 receptor sequence variant 7 (human)|hAMHR2/var:D491H|UniProtKB:Q16671-1, Asp-491, CHEBI:29979 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015531 20080301 PRO:CNA PR:000000082 anti-Muellerian hormone type-2 receptor sequence variant R504C (human) anti-Muellerian hormone type-2 receptor sequence variant 8 (human)|hAMHR2/var:R504C|UniProtKB:Q16671-1, Arg-504, CHEBI:29950 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8872466 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015532 20080301 PRO:CNA PR:000000092 fungal/metazoan cullin-1 CUL-1|CUL1 part_of GO:0019005 SCF ubiquitin ligase complex PANTHER:PTHR11932:SF19 ISS PANTHER:PTHR11932:SF19 PANTHER:PTHR11932:SF19|UniProtKB:Q13616|UniProtKB:Q9WTX6 20080301 PRO:CNA PR:000000092 fungal/metazoan cullin-1 CUL-1|CUL1 acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PANTHER:PTHR11932:SF19 ISS PANTHER:PTHR11932:SF19 PANTHER:PTHR11932:SF19|UniProtKB:Q13616|UniProtKB:Q9WTX6 20080301 PRO:CNA PR:000000093 cyclin-dependent kinase 4 inhibitor B CDKN2B|MTS-2|MTS2|multiple tumor suppressor 2|p14-INK4b|p15-INK4b|p15INK4B acts_upstream_of_or_within GO:0051726 regulation of cell cycle PANTHER:PTHR24144:SF138 ISS PANTHER:PTHR24144:SF138 PANTHER:PTHR24144:SF138 20080301 PRO:CNA PR:000000095 tumor necrosis factor ligand superfamily member 6 apoptosis antigen ligand|APT1LG1|APTL|CD178|CD95 ligand|CD95-L|CD95L|fas antigen ligand|fas ligand|fas ligand, TNF-like|FASL|FASLG|gld|TNFSF6 acts_upstream_of_or_within GO:0007267 cell-cell signaling PANTHER:PTHR11471:SF7 ISS PANTHER:PTHR11471:SF7 PANTHER:PTHR11471:SF7 20080301 PRO:CNA PR:000000099 inhibitory smad protein acts_upstream_of_or_within GO:0009968 negative regulation of signal transduction PIRSF:PIRSF500412 ISS PIRSF:PIRSF500412 PIRSF:PIRSF500412 20080301 PRO:CNA PR:000000099 inhibitory smad protein acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PIRSF:PIRSF500412 ISS PIRSF:PIRSF500412 PIRSF:PIRSF500412 20080301 PRO:CNA PR:000000099 inhibitory smad protein acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PIRSF:PIRSF500412 ISS PIRSF:PIRSF500412 PIRSF:PIRSF500412 20080301 PRO:CNA PR:000000102 lefty protein acts_upstream_of_or_within GO:0007275 multicellular organism development PIRSF:PIRSF037402 ISS PIRSF:PIRSF037402 PIRSF:PIRSF037402 20080301 PRO:CNA PR:000000105 nodal protein NODAL enables GO:0016015 morphogen activity PIRSF:PIRSF037400 ISS PIRSF:PIRSF037400 PIRSF:PIRSF037400|UniProtKB:P43021|UniProtKB:Q96S42 20080301 PRO:CNA PR:000000105 nodal protein NODAL acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PIRSF:PIRSF037400 ISS PIRSF:PIRSF037400 PIRSF:PIRSF037400|UniProtKB:P43021|UniProtKB:Q96S42 20080301 PRO:CNA PR:000000107 noggin sequence variant P35S (human) hNOG/var:P35S|noggin sequence variant 1 (human)|UniProtKB:Q13253, Pro-35, CHEBI:29999 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11857750 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_018324 20080301 PRO:CNA PR:000000108 noggin sequence variant P223L (human) hNOG/var:P223L|noggin sequence variant 10 (human)|UniProtKB:Q13253, Pro-223, CHEBI:30006 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011367 20080301 PRO:CNA PR:000000109 noggin sequence variant P35R (human) hNOG/var:P35R|noggin sequence variant 2 (human)|UniProtKB:Q13253, Pro-35, CHEBI:29952 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11545688 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011361 20080301 PRO:CNA PR:000000109 noggin sequence variant P35R (human) hNOG/var:P35R|noggin sequence variant 2 (human)|UniProtKB:Q13253, Pro-35, CHEBI:29952 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:11545688 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011361 20080301 PRO:CNA PR:000000110 noggin sequence variant C184Y (human) hNOG/var:C184Y|noggin sequence variant 3 (human)|UniProtKB:Q13253, Cys-184, CHEBI:46858 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11846737 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_018325 20080301 PRO:CNA PR:000000111 noggin sequence variant G189C (human) hNOG/var:G189C|noggin sequence variant 4 (human)|UniProtKB:Q13253, Gly-189, CHEBI:29950 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:99178269 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011362 20080301 PRO:CNA PR:000000112 noggin sequence variant R204L (human) hNOG/var:R204L|noggin sequence variant 5 (human)|UniProtKB:Q13253, Arg-204, CHEBI:30006 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:11545688 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011326 20080301 PRO:CNA PR:000000113 noggin sequence variant W217G (human) hNOG/var:W217G|noggin sequence variant 6 (human)|UniProtKB:Q13253, Trp-217, CHEBI:29947 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011363 20080301 PRO:CNA PR:000000114 noggin sequence variant I220N (human) hNOG/var:I220N|noggin sequence variant 7 (human)|UniProtKB:Q13253, Ile-220, CHEBI:50347 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011364 20080301 PRO:CNA PR:000000115 noggin sequence variant Y222C (human) hNOG/var:Y222C|noggin sequence variant 8 (human)|UniProtKB:Q13253, Tyr-222, CHEBI:29950 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:11545688 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011365 20080301 PRO:CNA PR:000000115 noggin sequence variant Y222C (human) hNOG/var:Y222C|noggin sequence variant 8 (human)|UniProtKB:Q13253, Tyr-222, CHEBI:29950 associated_with_disease_progression DOID:0050789 tarsal-carpal coalition syndrome PMID:10080184 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011365 20080301 PRO:CNA PR:000000116 noggin sequence variant Y222D (human) hNOG/var:Y222D|noggin sequence variant 9 (human)|UniProtKB:Q13253, Tyr-222, CHEBI:29958 associated_with_disease_progression DOID:0050788 proximal symphalangism PMID:10080184 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011366 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO enables GO:0003924 GTPase activity PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO enables GO:0005515 protein binding PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO enables GO:0005525 GTP binding PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO acts_upstream_of_or_within GO:0000902 cell morphogenesis PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO acts_upstream_of_or_within GO:0007264 small GTPase-mediated signal transduction PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000122 Rho-related small GTPase fam:RHO acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PIRSF:PIRSF037169 ISS PIRSF:PIRSF037169 PIRSF:PIRSF037169 20080301 PRO:CNA PR:000000125 zinc finger FYVE domain-containing protein 9 Madh-interacting protein|MADHIP|mothers against decapentaplegic homolog-interacting protein|novel serine protease|NSP|receptor activation anchor|SARA|smad anchor for receptor activation|SMADIP|ZFYVE9 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PANTHER:PTHR22835:SF7 ISS PANTHER:PTHR22835:SF7 PANTHER:PTHR22835:SF7|UniProtKB:A2A8R0|UniProtKB:O95405 20080301 PRO:CNA PR:000000127 smad ubiquitination regulatory factor smurf acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PIRSF:PIRSF500454 ISS PIRSF:PIRSF500454 PIRSF:PIRSF500454 20080301 PRO:CNA PR:000000127 smad ubiquitination regulatory factor smurf acts_upstream_of_or_within GO:0007398 ectoderm development PIRSF:PIRSF500454 ISS PIRSF:PIRSF500454 PIRSF:PIRSF500454 20080301 PRO:CNA PR:000000127 smad ubiquitination regulatory factor smurf acts_upstream_of_or_within GO:0009968 negative regulation of signal transduction PIRSF:PIRSF500454 ISS PIRSF:PIRSF500454 PIRSF:PIRSF500454 20080301 PRO:CNA PR:000000129 thrombospondin-1 glycoprotein G|THBS1|TSP|TSP1 acts_upstream_of_or_within GO:0007596 blood coagulation PANTHER:PTHR10199:SF37 ISS PANTHER:PTHR10199:SF37|UniProtKB:P07996|UniProtKB:P35441|UniProtKB:Q80YQ1|UniProtKB:Q8CGB2 PANTHER:PTHR10199:SF37|UniProtKB:P07996|UniProtKB:P35441|UniProtKB:Q80YQ1|UniProtKB:Q8CGB2 20080301 PRO:CNA PR:000000137 BMP receptor type-1A sequence variant Y62D (human) BMP receptor type-1A sequence variant 1 (human)|hBMPR1A/var:Y62D|UniProtKB:P36894, Tyr-62, CHEBI:29958 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022828 20080301 PRO:CNA PR:000000138 BMP receptor type-1A sequence variant C82Y (human) BMP receptor type-1A sequence variant 2 (human)|hBMPR1A/var:C82Y|UniProtKB:P36894, Cys-82, CHEBI:46858 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022829 20080301 PRO:CNA PR:000000139 BMP receptor type-1A sequence variant C124R (human) BMP receptor type-1A sequence variant 3 (human)|hBMPR1A/var:C124R|UniProtKB:P36894, Cys-124, CHEBI:29952 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:11536076 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015533 20080301 PRO:CNA PR:000000140 BMP receptor type-1A sequence variant C130R (human) BMP receptor type-1A sequence variant 4 (human)|hBMPR1A/var:C130R|UniProtKB:P36894, Cys-130, CHEBI:29952 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12136244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022830 20080301 PRO:CNA PR:000000141 BMP receptor type-1A sequence variant A338D (human) BMP receptor type-1A sequence variant 5 (human)|hBMPR1A/var:A338D|UniProtKB:P36894, Ala-338, CHEBI:29958 associated_with_disease_progression DOID:6457 Cowden syndrome PMID:11536076 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015534 20080301 PRO:CNA PR:000000142 BMP receptor type-1A sequence variant C376Y (human) BMP receptor type-1A sequence variant 6 (human)|hBMPR1A/var:C376Y|UniProtKB:P36894, Cys-376, CHEBI:46858 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:11536076 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015535 20080301 PRO:CNA PR:000000143 BMP receptor type-1A sequence variant R443C (human) BMP receptor type-1A sequence variant 7 (human)|hBMPR1A/var:R443C|UniProtKB:P36894, Arg-443, CHEBI:29950 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513|PMID:17344846 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022831 20080301 PRO:CNA PR:000000144 BMP receptor type-1A sequence variant M470T (human) BMP receptor type-1A sequence variant 8 (human)|hBMPR1A/var:M470T|UniProtKB:P36894, Met-470, CHEBI:30013 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12630959 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022832 20080301 PRO:CNA PR:000000146 BMP receptor type-1B sequence variant I200K (human) BMP receptor type-1B sequence variant 1 (human)|hBMPR1B/var:I200K|UniProtKB:O00238-1, Ile-200, CHEBI:29967 associated_with_disease_progression DOID:0050581 brachydactyly PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023819 20080301 PRO:CNA PR:000000146 BMP receptor type-1B sequence variant I200K (human) BMP receptor type-1B sequence variant 1 (human)|hBMPR1B/var:I200K|UniProtKB:O00238-1, Ile-200, CHEBI:29967 located_in GO:0009986 cell surface PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023819 20080301 PRO:CNA PR:000000146 BMP receptor type-1B sequence variant I200K (human) BMP receptor type-1B sequence variant 1 (human)|hBMPR1B/var:I200K|UniProtKB:O00238-1, Ile-200, CHEBI:29967 NOT enables GO:0004674 protein serine/threonine kinase activity PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023819 20080301 PRO:CNA PR:000000147 BMP receptor type-1B sequence variant R486W (human) BMP receptor type-1B sequence variant 2 (human)|hBMPR1B/var:R486W|UniProtKB:O00238-1, Arg-486, CHEBI:29954 associated_with_disease_progression DOID:0050581 brachydactyly PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023820 20080301 PRO:CNA PR:000000147 BMP receptor type-1B sequence variant R486W (human) BMP receptor type-1B sequence variant 2 (human)|hBMPR1B/var:R486W|UniProtKB:O00238-1, Arg-486, CHEBI:29954 enables GO:0004674 protein serine/threonine kinase activity PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023820 20080301 PRO:CNA PR:000000147 BMP receptor type-1B sequence variant R486W (human) BMP receptor type-1B sequence variant 2 (human)|hBMPR1B/var:R486W|UniProtKB:O00238-1, Arg-486, CHEBI:29954 located_in GO:0009986 cell surface PMID:14523231 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023820 20080301 PRO:CNA PR:000000149 BMP receptor type-2 sequence variant C60Y (human) BMP receptor type-2 sequence variant 1 (human)|hBMPR2/var:C60Y|UniProtKB:Q13873-1, Cys-60, CHEBI:46858 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11015450 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013670 20080301 PRO:CNA PR:000000150 BMP receptor type-2 sequence variant D485G (human) BMP receptor type-2 sequence variant 10 (human)|hBMPR2/var:D485G|UniProtKB:Q13873-1, Asp-485, CHEBI:29947 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:10973254 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013679 20080301 PRO:CNA PR:000000151 BMP receptor type-2 sequence variant R491Q (human) BMP receptor type-2 sequence variant 11 (human)|hBMPR2/var:R491Q|UniProtKB:Q13873-1, Arg-491, CHEBI:30011 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:10903931 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013680 20080301 PRO:CNA PR:000000152 BMP receptor type-2 sequence variant R491W (human) BMP receptor type-2 sequence variant 12 (human)|hBMPR2/var:R491W|UniProtKB:Q13873-1, Arg-491, CHEBI:29954 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:10903931 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013681 20080301 PRO:CNA PR:000000153 BMP receptor type-2 sequence variant K512T (human) BMP receptor type-2 sequence variant 13 (human)|hBMPR2/var:K512T|UniProtKB:Q13873-1, Lys-512, CHEBI:30013 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11115378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013682 20080301 PRO:CNA PR:000000154 BMP receptor type-2 sequence variant N519K (human) BMP receptor type-2 sequence variant 14 (human)|hBMPR2/var:N519K|UniProtKB:Q13873-1, Asn-519, CHEBI:29967 associated_with_disease_progression DOID:14557 primary pulmonary hypertension UniProtKB_VAR:VAR_013683 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013683 20080301 PRO:CNA PR:000000155 BMP receptor type-2 sequence variant C117Y (human) BMP receptor type-2 sequence variant 2 (human)|hBMPR2/var:C117Y|UniProtKB:Q13873-1, Cys-117, CHEBI:46858 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11015450 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013671 20080301 PRO:CNA PR:000000156 BMP receptor type-2 sequence variant C118W (human) BMP receptor type-2 sequence variant 3 (human)|hBMPR2/var:C118W|UniProtKB:Q13873-1, Cys-118, CHEBI:29954 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:10973254 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013672 20080301 PRO:CNA PR:000000157 BMP receptor type-2 sequence variant C123R (human) BMP receptor type-2 sequence variant 4 (human)|hBMPR2/var:C123R|UniProtKB:Q13873-1, Cys-123, CHEBI:29952 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11115378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013673 20080301 PRO:CNA PR:000000158 BMP receptor type-2 sequence variant C123S (human) BMP receptor type-2 sequence variant 5 (human)|hBMPR2/var:C123S|UniProtKB:Q13873-1, Cys-123, CHEBI:29999 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11115378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013674 20080301 PRO:CNA PR:000000159 BMP receptor type-2 sequence variant E224D (human) BMP receptor type-2 sequence variant 6 (human)|hBMPR2/var:E224D|UniProtKB:Q13873-1, Glu-224, CHEBI:29958 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11115378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013675 20080301 PRO:CNA PR:000000160 BMP receptor type-2 sequence variant C347Y (human) BMP receptor type-2 sequence variant 7 (human)|hBMPR2/var:C347Y|UniProtKB:Q13873-1, Cys-347, CHEBI:46858 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:10973254 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013676 20080301 PRO:CNA PR:000000161 BMP receptor type-2 sequence variant C420R (human) BMP receptor type-2 sequence variant 8 (human)|hBMPR2/var:C420R|UniProtKB:Q13873-1, Cys-420, CHEBI:29952 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11115378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013677 20080301 PRO:CNA PR:000000162 BMP receptor type-2 sequence variant C483R (human) BMP receptor type-2 sequence variant 9 (human)|hBMPR2/var:C483R|UniProtKB:Q13873-1, Cys-483, CHEBI:29952 associated_with_disease_progression DOID:14557 primary pulmonary hypertension PMID:11015450|PMID:12358323 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013678 20080301 PRO:CNA PR:000000164 bone morphogenetic protein 2 BMP-2|BMP-2A|BMP2|BMP2A|bone morphogenetic protein 2A acts_upstream_of_or_within GO:0001501 skeletal system development PANTHER:PTHR11848:SF50 ISS PANTHER:PTHR11848:SF50 PANTHER:PTHR11848:SF50|UniProtKB:P12643|UniProtKB:P21274|UniProtKB:Q3V1I4|UniProtKB:Q497W8 20080301 PRO:CNA PR:000000164 bone morphogenetic protein 2 BMP-2|BMP-2A|BMP2|BMP2A|bone morphogenetic protein 2A acts_upstream_of_or_within GO:0007267 cell-cell signaling PANTHER:PTHR11848:SF50 ISS PANTHER:PTHR11848:SF50 PANTHER:PTHR11848:SF50|UniProtKB:P12643|UniProtKB:P21274|UniProtKB:Q3V1I4|UniProtKB:Q497W8 20080301 PRO:CNA PR:000000164 bone morphogenetic protein 2 BMP-2|BMP-2A|BMP2|BMP2A|bone morphogenetic protein 2A acts_upstream_of_or_within GO:0030509 BMP signaling pathway PANTHER:PTHR11848:SF50 ISS PANTHER:PTHR11848:SF50 PANTHER:PTHR11848:SF50|UniProtKB:P12643|UniProtKB:P21274|UniProtKB:Q3V1I4|UniProtKB:Q497W8 20080301 PRO:CNA PR:000000165 bone morphogenetic protein 4 BMP-2B|BMP-4|BMP2B|BMP4|bone morphogenetic protein 2B|Dvr-4|DVR4 acts_upstream_of_or_within GO:0001501 skeletal system development PANTHER:PTHR11848:SF49 ISS PANTHER:PTHR11848:SF49 PANTHER:PTHR11848:SF49|UniProtKB:P12644|UniProtKB:P21275|UniProtKB:Q3ULR1 20080301 PRO:CNA PR:000000182 TGF-beta 1 TGF-beta-1|TGFB|TGFB1 acts_upstream_of_or_within GO:0008283 cell population proliferation PANTHER:PTHR11848:SF32 ISS PANTHER:PTHR11848:SF32 PANTHER:PTHR11848:SF32 20080301 PRO:CNA PR:000000182 TGF-beta 1 TGF-beta-1|TGFB|TGFB1 acts_upstream_of_or_within GO:0030154 cell differentiation PANTHER:PTHR11848:SF32 ISS PANTHER:PTHR11848:SF32 PANTHER:PTHR11848:SF32 20080301 PRO:CNA PR:000000183 TGF-beta 2 BSC-1 cell growth inhibitor|cetermin|G-TSF|glioblastoma-derived T-cell suppressor factor|polyergin|TGF-beta-2|TGFB2 acts_upstream_of_or_within GO:0008283 cell population proliferation PANTHER:PTHR11848:SF33 ISS PANTHER:PTHR11848:SF33 PANTHER:PTHR11848:SF33 20080301 PRO:CNA PR:000000186 TGF-beta receptor type-1 sequence variant T200I (human) hTGFBR1/var:T200I|TGF-beta receptor type-1 sequence variant 1 (human)|UniProtKB:P36897, Thr-200, CHEBI:30009|UniProtKB:P36897-1, Thr-200, CHEBI:30009 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022344 20080301 PRO:CNA PR:000000187 TGF-beta receptor type-1 sequence variant 10 (human) hTGFBR1/var:10|TGFBR1*10A has_agent SO:0001605 amino_acid_insertion PMID:9661882 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022343 20080301 PRO:CNA PR:000000188 TGF-beta receptor type-1 sequence variant 11 (human) hTGFBR1/var:11|TGFBR1*6A (human)|UniProtKB:P36897, 1-23, 27-503|UniProtKB:P36897-1, 1-23, 27-503 acts_upstream_of_or_within GO:0007165 signal transduction PMID:9661882 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022342 20080301 PRO:CNA PR:000000188 TGF-beta receptor type-1 sequence variant 11 (human) hTGFBR1/var:11|TGFBR1*6A (human)|UniProtKB:P36897, 1-23, 27-503|UniProtKB:P36897-1, 1-23, 27-503 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:9661882 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022342 20080301 PRO:CNA PR:000000189 TGF-beta receptor type-1 sequence variant K232E (human) hTGFBR1/var:K232E|TGF-beta receptor type-1 sequence variant 2 (human)|UniProtKB:P36897-1, Lys-232, CHEBI:29972 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:16928994 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029481 20080301 PRO:CNA PR:000000190 TGF-beta receptor type-1 sequence variant S241L (human) hTGFBR1/var:S241L|TGF-beta receptor type-1 sequence variant 3 (human)|UniProtKB:P36897-1, Ser-241, CHEBI:30006 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:16596670|PMID:16791849 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029482 20080301 PRO:CNA PR:000000191 TGF-beta receptor type-1 sequence variant N267H (human) hTGFBR1/var:N267H|TGF-beta receptor type-1 sequence variant 4 (human)|UniProtKB:P36897-1, Asn-267, CHEBI:29979 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:16791849 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029483 20080301 PRO:CNA PR:000000192 TGF-beta receptor type-1 sequence variant M318R (human) hTGFBR1/var:M318R|TGF-beta receptor type-1 sequence variant 5 (human)|UniProtKB:P36897-1, Met-318, CHEBI:29952 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022345 20080301 PRO:CNA PR:000000193 TGF-beta receptor type-1 sequence variant D400G (human) hTGFBR1/var:D400G|TGF-beta receptor type-1 sequence variant 6 (human)|UniProtKB:P36897-1, Asp-400, CHEBI:29947 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15731757 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022346 20080301 PRO:CNA PR:000000194 TGF-beta receptor type-1 sequence variant R487P (human) hTGFBR1/var:R487P|TGF-beta receptor type-1 sequence variant 7 (human)|UniProtKB:P36897-1, Arg-487, CHEBI:50342 associated_with_disease_progression DOID:14756 vascular type Ehlers-Danlos syndrome PMID:15731757|PMID:16928994 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022347 20080301 PRO:CNA PR:000000195 TGF-beta receptor type-1 sequence variant R487E (human) hTGFBR1/var:R487E|TGF-beta receptor type-1 sequence variant 8 (human)|UniProtKB:P36897-1, Arg-487, CHEBI:29972 associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:16791849|PMID:16928994 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029484 20080301 PRO:CNA PR:000000196 TGF-beta receptor type-1 sequence variant R487W (human) hTGFBR1/var:R487W|TGF-beta receptor type-1 sequence variant 9 (human)|UniProtKB:P36897-1, Arg-487, CHEBI:29954 associated_with_disease_progression DOID:14756 vascular type Ehlers-Danlos syndrome PMID:16928994 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_029485 20080301 PRO:CNA PR:000000200 activin receptor type-1 sequence variant R206H (human) activin receptor type-1 sequence variant 1 (human)|hACVR1/var:R206H|UniProtKB:Q04771, Arg-206, CHEBI:29979 associated_with_disease_progression DOID:13374 fibrodysplasia ossificans progressiva PMID:8397373 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_028244 20080301 PRO:CNA PR:000000200 activin receptor type-1 sequence variant R206H (human) activin receptor type-1 sequence variant 1 (human)|hACVR1/var:R206H|UniProtKB:Q04771, Arg-206, CHEBI:29979 located_in GO:0005886 plasma membrane PMID:8397373 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_028444 20080301 PRO:CNA PR:000000214 activin receptor type-2B sequence variant R40H (human) activin receptor type-2B sequence variant 1 (human)|hACVR2B/var:R40H|UniProtKB:Q13705-1, Arg-40, CHEBI:29979 associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:9916847 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013281 20080301 PRO:CNA PR:000000215 activin receptor type-2B sequence variant V494I (human) activin receptor type-2B sequence variant 2 (human)|hACVR2B/var:V494I|UniProtKB:Q13705-1, Val-494, CHEBI:30009 associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:9916847 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_013282 20080301 PRO:CNA PR:000000221 Muellerian-inhibiting factor sequence variant V12G (human) anti-Muellerian hormone sequence variant 1 (human)|hAMH/var:V12G|UniProtKB:P03971, Val-12, CHEBI:29947 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007483 20080301 PRO:CNA PR:000000222 Muellerian-inhibiting factor sequence variant L70P (human) anti-Muellerian hormone sequence variant 2 (human)|hAMH/var:L70P|UniProtKB:P03971, Leu-70, CHEBI:50342 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007485 20080301 PRO:CNA PR:000000223 Muellerian-inhibiting factor sequence variant G101V (human) anti-Muellerian hormone sequence variant 3 (human)|hAMH/var:G101V|UniProtKB:P03971, Gly-101, CHEBI:30015 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007486 20080301 PRO:CNA PR:000000224 Muellerian-inhibiting factor sequence variant R123W (human) anti-Muellerian hormone sequence variant 4 (human)|hAMH/var:R123W|UniProtKB:P03971, Arg-123, CHEBI:29954 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007487 20080301 PRO:CNA PR:000000225 Muellerian-inhibiting factor sequence variant Y167C (human) anti-Muellerian hormone sequence variant 5 (human)|hAMH/var:Y167C|UniProtKB:P03971, Tyr-167, CHEBI:29950 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007488 20080301 PRO:CNA PR:000000226 Muellerian-inhibiting factor sequence variant R194C (human) anti-Muellerian hormone sequence variant 6 (human)|hAMH/var:R194C|UniProtKB:P03971, Arg-194, CHEBI:29950 associated_with_disease_progression DOID:0050791 persistent Mullerian duct syndrome PMID:14673134|PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007490 20080301 PRO:CNA PR:000000226 Muellerian-inhibiting factor sequence variant R194C (human) anti-Muellerian hormone sequence variant 6 (human)|hAMH/var:R194C|UniProtKB:P03971, Arg-194, CHEBI:29950 has_agent SO:0001555 decreased_translational_product_level PMID:14673134|PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007490 20080301 PRO:CNA PR:000000226 Muellerian-inhibiting factor sequence variant R194C (human) anti-Muellerian hormone sequence variant 6 (human)|hAMH/var:R194C|UniProtKB:P03971, Arg-194, CHEBI:29950 has_agent SO:0001558 polypeptide_localization_variant PMID:14673134|PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007490 20080301 PRO:CNA PR:000000227 Muellerian-inhibiting factor sequence variant V477A (human) anti-Muellerian hormone sequence variant 7 (human)|hAMH/var:V477A|UniProtKB:P03971, Val-477, CHEBI:46217 has_agent SO:0001558 polypeptide_localization_variant PMID:8162013 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007492 20080301 PRO:CNA PR:000000231 cartilage oligomeric matrix protein sequence variant P276R (human) cartilage oligomeric matrix protein sequence variant 1 (human)|hCOMP/var:P276R|UniProtKB:P49747-1, Pro-276, CHEBI:29952 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:11565064 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026239 20080301 PRO:CNA PR:000000232 cartilage oligomeric matrix protein sequence variant C387G (human) cartilage oligomeric matrix protein sequence variant 10 (human)|hCOMP/var:C387G|UniProtKB:P49747-1, Cys-387, CHEBI:29947 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007625 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007625 20080301 PRO:CNA PR:000000233 cartilage oligomeric matrix protein sequence variant D408Y (human) cartilage oligomeric matrix protein sequence variant 11 (human)|hCOMP/var:D408Y|UniProtKB:P49747-1, Asp-408, CHEBI:46858 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007627 20080301 PRO:CNA PR:000000234 cartilage oligomeric matrix protein sequence variant D420A (human) cartilage oligomeric matrix protein sequence variant 12 (human)|hCOMP/var:D420A|UniProtKB:P49747-1, Asp-420, CHEBI:46217 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:11565064 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026240 20080301 PRO:CNA PR:000000235 cartilage oligomeric matrix protein sequence variant G440E (human) cartilage oligomeric matrix protein sequence variant 13 (human)|hCOMP/var:G440E|UniProtKB:P49747-1, Gly-440, CHEBI:29972 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007628 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007628 20080301 PRO:CNA PR:000000236 cartilage oligomeric matrix protein sequence variant G440R (human) cartilage oligomeric matrix protein sequence variant 14 (human)|hCOMP/var:G440R|UniProtKB:P49747-1, Gly-440, CHEBI:29952 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007629 20080301 PRO:CNA PR:000000237 cartilage oligomeric matrix protein sequence variant N453S (human) cartilage oligomeric matrix protein sequence variant 15 (human)|hCOMP/var:N453S|UniProtKB:P49747-1, Asn-453, CHEBI:29999 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007630 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007630 20080301 PRO:CNA PR:000000238 cartilage oligomeric matrix protein sequence variant D439V (human) cartilage oligomeric matrix protein sequence variant 16 (human)|hCOMP/var:D439V|UniProtKB:P49747-1, Asp-439, CHEBI:30015 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007618 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007618 20080301 PRO:CNA PR:000000239 cartilage oligomeric matrix protein sequence variant C468Y (human) cartilage oligomeric matrix protein sequence variant 17 (human)|hCOMP/var:C468Y|UniProtKB:P49747-1, Cys-468, CHEBI:46858 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:7670471|PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007632 20080301 PRO:CNA PR:000000240 cartilage oligomeric matrix protein sequence variant D472Y (human) cartilage oligomeric matrix protein sequence variant 18 (human)|hCOMP/var:D472Y|UniProtKB:P49747-1, Asp-472, CHEBI:46858 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:7670471|PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007634 20080301 PRO:CNA PR:000000241 cartilage oligomeric matrix protein sequence variant D473G (human) cartilage oligomeric matrix protein sequence variant 19 (human)|hCOMP/var:D473G|UniProtKB:P49747-1, Asp-473, CHEBI:29947 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007635 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007635 20080301 PRO:CNA PR:000000242 cartilage oligomeric matrix protein sequence variant D290N (human) cartilage oligomeric matrix protein sequence variant 2 (human)|hCOMP/var:D290N|UniProtKB:P49747-1, Asp-290, CHEBI:50347 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007614 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007614 20080301 PRO:CNA PR:000000243 cartilage oligomeric matrix protein sequence variant D482G (human) cartilage oligomeric matrix protein sequence variant 20 (human)|hCOMP/var:D482G|UniProtKB:P49747-1, Asp-482, CHEBI:29947 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:9452063 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007637 20080301 PRO:CNA PR:000000244 cartilage oligomeric matrix protein sequence variant D518N (human) cartilage oligomeric matrix protein sequence variant 21 (human)|hCOMP/var:D518N|UniProtKB:P49747-1, Asp-518, CHEBI:50347 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007639 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007639 20080301 PRO:CNA PR:000000245 cartilage oligomeric matrix protein sequence variant G719D (human) cartilage oligomeric matrix protein sequence variant 22 (human)|hCOMP/var:G719D|UniProtKB:P49747-1, Gly-719, CHEBI:29958 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:11746044 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017103 20080301 PRO:CNA PR:000000246 cartilage oligomeric matrix protein sequence variant N523K (human) cartilage oligomeric matrix protein sequence variant 23 (human)|hCOMP/var:N523K|UniProtKB:P49747-1, Asn-523, CHEBI:29967 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:9021009 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007640 20080301 PRO:CNA PR:000000247 cartilage oligomeric matrix protein sequence variant T585M (human) cartilage oligomeric matrix protein sequence variant 24 (human)|hCOMP/var:T585M|UniProtKB:P49747-1, Thr-585, CHEBI:16044 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:11565064 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007641 20080301 PRO:CNA PR:000000247 cartilage oligomeric matrix protein sequence variant T585M (human) cartilage oligomeric matrix protein sequence variant 24 (human)|hCOMP/var:T585M|UniProtKB:P49747-1, Thr-585, CHEBI:16044 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:11565064 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007641 20080301 PRO:CNA PR:000000248 cartilage oligomeric matrix protein sequence variant T585R (human) cartilage oligomeric matrix protein sequence variant 25 (human)|hCOMP/var:T585R|UniProtKB:P49747-1, Thr-585, CHEBI:29952 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007642 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007642 20080301 PRO:CNA PR:000000249 cartilage oligomeric matrix protein sequence variant 26 (human) hCOMP/var:26 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007626 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007626 20080301 PRO:CNA PR:000000250 cartilage oligomeric matrix protein sequence variant D372del (human) cartilage oligomeric matrix protein sequence variant 27 (human)|hCOMP/var:D372del|UniProtKB:P49747-1, 21-371, 373-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007623 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007623 20080301 PRO:CNA PR:000000251 cartilage oligomeric matrix protein sequence variant D374del (human) cartilage oligomeric matrix protein sequence variant 28 (human)|hCOMP/var:D374del|UniProtKB:P49747-1, 21-373, 375-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007624 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007624 20080301 PRO:CNA PR:000000252 cartilage oligomeric matrix protein sequence variant S459del (human) cartilage oligomeric matrix protein sequence variant 29 (human)|hCOMP/var:S459del|UniProtKB:P49747-1, 21-458, 460-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007631 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007631 20080301 PRO:CNA PR:000000253 cartilage oligomeric matrix protein sequence variant G299R (human) cartilage oligomeric matrix protein sequence variant 3 (human)|hCOMP/var:G299R|UniProtKB:P49747-1, Gly-299, CHEBI:29952 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007615 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007615 20080301 PRO:CNA PR:000000254 cartilage oligomeric matrix protein sequence variant D469del (human) cartilage oligomeric matrix protein sequence variant 30 (human)|hCOMP/var:D469del|UniProtKB:P49747-1, 21-468, 470-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007633 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007633 20080301 PRO:CNA PR:000000255 cartilage oligomeric matrix protein sequence variant D473del (human) cartilage oligomeric matrix protein sequence variant 31 (human)|hCOMP/var:D473del|UniProtKB:P49747-1, 21-472, 474-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007636 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007636 20080301 PRO:CNA PR:000000256 cartilage oligomeric matrix protein sequence variant 32 (human) hCOMP/var:32|UniProtKB:P49747-1, 21-366, 369-757 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007621 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007621 20080301 PRO:CNA PR:000000257 cartilage oligomeric matrix protein sequence variant 33 (human) hCOMP/var:33|UniProtKB:P49747-1, 21-512, 517-757 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007638 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007638 20080301 PRO:CNA PR:000000258 cartilage oligomeric matrix protein sequence variant C328R (human) cartilage oligomeric matrix protein sequence variant 4 (human)|hCOMP/var:C328R|UniProtKB:P49747-1, Cys-328, CHEBI:29952 associated_with_disease_progression DOID:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007616 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007616 20080301 PRO:CNA PR:000000259 cartilage oligomeric matrix protein sequence variant D342Y (human) cartilage oligomeric matrix protein sequence variant 5 (human)|hCOMP/var:D342Y|UniProtKB:P49747-1, Asp-342, CHEBI:46858 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:7670472|PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007617 20080301 PRO:CNA PR:000000260 cartilage oligomeric matrix protein sequence variant C348R (human) cartilage oligomeric matrix protein sequence variant 6 (human)|hCOMP/var:C348R|UniProtKB:P49747-1, Cys-348, CHEBI:29952 associated_with_disease_progression DOID:0080047 pseudoachondroplasia PMID:11746045 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017102 20080301 PRO:CNA PR:000000261 cartilage oligomeric matrix protein sequence variant D361V (human) cartilage oligomeric matrix protein sequence variant 7 (human)|hCOMP/var:D361V|UniProtKB:P49747-1, Asp-361, CHEBI:30015 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007619 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007619 20080301 PRO:CNA PR:000000262 cartilage oligomeric matrix protein sequence variant D361Y (human) cartilage oligomeric matrix protein sequence variant 8 (human)|hCOMP/var:D361Y|UniProtKB:P49747-1, Asp-361, CHEBI:46858 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:9452026 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007620 20080301 PRO:CNA PR:000000263 cartilage oligomeric matrix protein sequence variant C371S (human) cartilage oligomeric matrix protein sequence variant 9 (human)|hCOMP/var:C371S|UniProtKB:P49747-1, Cys-371, CHEBI:29999 associated_with_disease_progression DOID:12721 multiple epiphyseal dysplasia PMID:9184241 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_007622 20080301 PRO:CNA PR:000000266 CREB-binding protein sequence variant R1378P (human) CREB-binding protein sequence variant 1 (human)|hCREBBP/var:R1378P|UniProtKB:Q92793-1, Arg-1378, CHEBI:50342 associated_with_disease_progression DOID:1933 Rubinstein-Taybi syndrome PMID:11331617 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015578 20080301 PRO:CNA PR:000000266 CREB-binding protein sequence variant R1378P (human) CREB-binding protein sequence variant 1 (human)|hCREBBP/var:R1378P|UniProtKB:Q92793-1, Arg-1378, CHEBI:50342 has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:11331617 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015578 20080301 PRO:CNA PR:000000266 CREB-binding protein sequence variant R1378P (human) CREB-binding protein sequence variant 1 (human)|hCREBBP/var:R1378P|UniProtKB:Q92793-1, Arg-1378, CHEBI:50342 NOT enables GO:0004402 histone acetyltransferase activity PMID:11331617 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015578 20080301 PRO:CNA PR:000000281 growth/differentiation factor 5 BMP-14|BMP14|bone morphogenetic protein 14|Bp|cartilage-derived morphogenetic protein 1|CDMP-1|CDMP1|GDF-5|GDF5|radotermin acts_upstream_of_or_within GO:0030326 embryonic limb morphogenesis PANTHER:PTHR11848:SF44 ISS PANTHER:PTHR11848:SF44 PANTHER:PTHR11848:SF44|UniProtKB:P43026|UniProtKB:P43027 20080301 PRO:CNA PR:000000282 growth/differentiation factor 7 GDF-7|GDF7 acts_upstream_of_or_within GO:0007154 cell communication PANTHER:PTHR11848:SF42 ISS PANTHER:PTHR11848:SF42 PANTHER:PTHR11848:SF42|UniProtKB:P43029|UniProtKB:Q7Z4P5 20080301 PRO:CNA PR:000000292 nodal protein sequence variant R183Q (human) hNODAL/var:R183Q|nodal protein sequence variant 1 (human)|UniProtKB:Q96S42, Arg-183, CHEBI:30011 associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:9354794 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015111 20080301 PRO:CNA PR:000000298 pituitary homeobox 2 sequence variant R89W (human) hPITX2/var:R89W|pituitary homeobox 2 sequence variant 1 (human)|UniProtKB:Q99697-1, Arg-89, CHEBI:29954 associated_with_disease_progression DOID:0050786 iridogoniodysgenesis syndrome PMID:9437321 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_003762 20080301 PRO:CNA PR:000000299 pituitary homeobox 2 sequence variant L100Q (human) hPITX2/var:L100Q|pituitary homeobox 2 sequence variant 2 (human)|UniProtKB:Q99697-1, Leu-100, CHEBI:30011 associated_with_disease_progression DOID:14686 Axenfeld-Rieger syndrome PMID:8944018 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_003763 20080301 PRO:CNA PR:000000300 pituitary homeobox 2 sequence variant T114P (human) hPITX2/var:T114P|pituitary homeobox 2 sequence variant 3 (human)|UniProtKB:Q99697-1, Thr-114, CHEBI:50342 associated_with_disease_progression DOID:14686 Axenfeld-Rieger syndrome PMID:8944018 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_003764 20080301 PRO:CNA PR:000000301 pituitary homeobox 2 sequence variant R115H (human) hPITX2/var:R115H|pituitary homeobox 2 sequence variant 4 (human)|UniProtKB:Q99697-1, Arg-115, CHEBI:29979 associated_with_disease_progression DOID:0050786 iridogoniodysgenesis syndrome PMID:9618168 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_003765 20080301 PRO:CNA PR:000000302 pituitary homeobox 2 sequence variant R137P (human) hPITX2/var:R137P|pituitary homeobox 2 sequence variant 5 (human)|UniProtKB:Q99697-1, Arg-137, CHEBI:50342 associated_with_disease_progression DOID:14686 Axenfeld-Rieger syndrome PMID:8944018 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_003766 20080301 PRO:CNA PR:000000317 serine/threonine-protein kinase receptor R3 sequence variant G48R (human) hACVRL1/var:G48R|serine/threonine-protein kinase receptor R3 sequence variant 1 (human)|UniProtKB:P37023, Gly-48, CHEBI:29952 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026785 20080301 PRO:CNA PR:000000318 serine/threonine-protein kinase receptor R3 sequence variant E215K (human) hACVRL1/var:E215K|serine/threonine-protein kinase receptor R3 sequence variant 10 (human)|UniProtKB:P37023, Glu-215, CHEBI:29967 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026789 20080301 PRO:CNA PR:000000319 serine/threonine-protein kinase receptor R3 sequence variant H222del (human) hACVRL1/var:H222del|serine/threonine-protein kinase receptor R3 sequence variant 11 (human)|UniProtKB:P37023, 22-221, 223-503 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia UniProtKB_VAR:VAR_006209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006209 20080301 PRO:CNA PR:000000319 serine/threonine-protein kinase receptor R3 sequence variant H222del (human) hACVRL1/var:H222del|serine/threonine-protein kinase receptor R3 sequence variant 11 (human)|UniProtKB:P37023, 22-221, 223-503 located_in GO:0005886 plasma membrane PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006209 20080301 PRO:CNA PR:000000320 serine/threonine-protein kinase receptor R3 sequence variant S233del (human) hACVRL1/var:S233del|serine/threonine-protein kinase receptor R3 sequence variant 12 (human)|UniProtKB:P37023, 22-232, 234-503 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia UniProtKB_VAR:VAR_026792 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026792 20080301 PRO:CNA PR:000000321 serine/threonine-protein kinase receptor R3 sequence variant G223R (human) hACVRL1/var:G223R|serine/threonine-protein kinase receptor R3 sequence variant 13 (human)|UniProtKB:P37023, Gly-223, CHEBI:29952 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026790 20080301 PRO:CNA PR:000000322 serine/threonine-protein kinase receptor R3 sequence variant K229R (human) hACVRL1/var:K229R|serine/threonine-protein kinase receptor R3 sequence variant 14 (human)|UniProtKB:P37023, Lys-229, CHEBI:29952 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026791 20080301 PRO:CNA PR:000000323 serine/threonine-protein kinase receptor R3 sequence variant D254del (human) hACVRL1/var:D254del|serine/threonine-protein kinase receptor R3 sequence variant 15 (human)|UniProtKB:P37023, 22-253, 255-503 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia UniProtKB_VAR:VAR_026793 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026793 20080301 PRO:CNA PR:000000323 serine/threonine-protein kinase receptor R3 sequence variant D254del (human) hACVRL1/var:D254del|serine/threonine-protein kinase receptor R3 sequence variant 15 (human)|UniProtKB:P37023, 22-253, 255-503 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026793 20080301 PRO:CNA PR:000000323 serine/threonine-protein kinase receptor R3 sequence variant D254del (human) hACVRL1/var:D254del|serine/threonine-protein kinase receptor R3 sequence variant 15 (human)|UniProtKB:P37023, 22-253, 255-503 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026793 20080301 PRO:CNA PR:000000324 serine/threonine-protein kinase receptor R3 sequence variant M376V (human) hACVRL1/var:M376V|serine/threonine-protein kinase receptor R3 sequence variant 16 (human)|UniProtKB:P37023, Met-376, CHEBI:30015 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026801 20080301 PRO:CNA PR:000000325 serine/threonine-protein kinase receptor R3 sequence variant L285F (human) hACVRL1/var:L285F|serine/threonine-protein kinase receptor R3 sequence variant 17 (human)|UniProtKB:P37023, Leu-285, CHEBI:29997 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026794 20080301 PRO:CNA PR:000000326 serine/threonine-protein kinase receptor R3 sequence variant A306P (human) hACVRL1/var:A306P|serine/threonine-protein kinase receptor R3 sequence variant 18 (human)|UniProtKB:P37023, Ala-306, CHEBI:50342 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026795 20080301 PRO:CNA PR:000000327 serine/threonine-protein kinase receptor R3 sequence variant H314Y (human) hACVRL1/var:H314Y|serine/threonine-protein kinase receptor R3 sequence variant 19 (human)|UniProtKB:P37023, His-314, CHEBI:46858 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026796 20080301 PRO:CNA PR:000000328 serine/threonine-protein kinase receptor R3 sequence variant W50C (human) hACVRL1/var:W50C|serine/threonine-protein kinase receptor R3 sequence variant 2 (human)|UniProtKB:P37023, Trp-50, CHEBI:29950 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10767348|PMID:14684682|PMID:9245985 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006204 20080301 PRO:CNA PR:000000328 serine/threonine-protein kinase receptor R3 sequence variant W50C (human) hACVRL1/var:W50C|serine/threonine-protein kinase receptor R3 sequence variant 2 (human)|UniProtKB:P37023, Trp-50, CHEBI:29950 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006204 20080301 PRO:CNA PR:000000328 serine/threonine-protein kinase receptor R3 sequence variant W50C (human) hACVRL1/var:W50C|serine/threonine-protein kinase receptor R3 sequence variant 2 (human)|UniProtKB:P37023, Trp-50, CHEBI:29950 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006204 20080301 PRO:CNA PR:000000329 serine/threonine-protein kinase receptor R3 sequence variant S333I (human) hACVRL1/var:S333I|serine/threonine-protein kinase receptor R3 sequence variant 20 (human)|UniProtKB:P37023, Ser-333, CHEBI:30009 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10767348|PMID:14684682|PMID:9245985 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006210 20080301 PRO:CNA PR:000000329 serine/threonine-protein kinase receptor R3 sequence variant S333I (human) hACVRL1/var:S333I|serine/threonine-protein kinase receptor R3 sequence variant 20 (human)|UniProtKB:P37023, Ser-333, CHEBI:30009 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006210 20080301 PRO:CNA PR:000000329 serine/threonine-protein kinase receptor R3 sequence variant S333I (human) hACVRL1/var:S333I|serine/threonine-protein kinase receptor R3 sequence variant 20 (human)|UniProtKB:P37023, Ser-333, CHEBI:30009 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006210 20080301 PRO:CNA PR:000000330 serine/threonine-protein kinase receptor R3 sequence variant L337P (human) hACVRL1/var:L337P|serine/threonine-protein kinase receptor R3 sequence variant 21 (human)|UniProtKB:P37023, Leu-337, CHEBI:50342 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026797 20080301 PRO:CNA PR:000000331 serine/threonine-protein kinase receptor R3 sequence variant C344Y (human) hACVRL1/var:C344Y|serine/threonine-protein kinase receptor R3 sequence variant 22 (human)|UniProtKB:P37023, Cys-344, CHEBI:46858 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10767348|PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026798 20080301 PRO:CNA PR:000000331 serine/threonine-protein kinase receptor R3 sequence variant C344Y (human) hACVRL1/var:C344Y|serine/threonine-protein kinase receptor R3 sequence variant 22 (human)|UniProtKB:P37023, Cys-344, CHEBI:46858 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026798 20080301 PRO:CNA PR:000000331 serine/threonine-protein kinase receptor R3 sequence variant C344Y (human) hACVRL1/var:C344Y|serine/threonine-protein kinase receptor R3 sequence variant 22 (human)|UniProtKB:P37023, Cys-344, CHEBI:46858 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026798 20080301 PRO:CNA PR:000000332 serine/threonine-protein kinase receptor R3 sequence variant A347P (human) hACVRL1/var:A347P|serine/threonine-protein kinase receptor R3 sequence variant 23 (human)|UniProtKB:P37023, Ala-347, CHEBI:50342 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026799 20080301 PRO:CNA PR:000000333 serine/threonine-protein kinase receptor R3 sequence variant R374Q (human) hACVRL1/var:R374Q|serine/threonine-protein kinase receptor R3 sequence variant 24 (human)|UniProtKB:P37023, Arg-374, CHEBI:30011 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682|PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026800 20080301 PRO:CNA PR:000000333 serine/threonine-protein kinase receptor R3 sequence variant R374Q (human) hACVRL1/var:R374Q|serine/threonine-protein kinase receptor R3 sequence variant 24 (human)|UniProtKB:P37023, Arg-374, CHEBI:30011 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026800 20080301 PRO:CNA PR:000000333 serine/threonine-protein kinase receptor R3 sequence variant R374Q (human) hACVRL1/var:R374Q|serine/threonine-protein kinase receptor R3 sequence variant 24 (human)|UniProtKB:P37023, Arg-374, CHEBI:30011 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026800 20080301 PRO:CNA PR:000000334 serine/threonine-protein kinase receptor R3 sequence variant R374W (human) hACVRL1/var:R374W|serine/threonine-protein kinase receptor R3 sequence variant 25 (human)|UniProtKB:P37023, Arg-374, CHEBI:29954 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11170071|PMID:14684682|PMID:15712270|PMID:9245985 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006211 20080301 PRO:CNA PR:000000335 serine/threonine-protein kinase receptor R3 sequence variant P378L (human) hACVRL1/var:P378L|serine/threonine-protein kinase receptor R3 sequence variant 26 (human)|UniProtKB:P37023, Pro-378, CHEBI:30006 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026802 20080301 PRO:CNA PR:000000335 serine/threonine-protein kinase receptor R3 sequence variant P378L (human) hACVRL1/var:P378L|serine/threonine-protein kinase receptor R3 sequence variant 26 (human)|UniProtKB:P37023, Pro-378, CHEBI:30006 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026802 20080301 PRO:CNA PR:000000335 serine/threonine-protein kinase receptor R3 sequence variant P378L (human) hACVRL1/var:P378L|serine/threonine-protein kinase receptor R3 sequence variant 26 (human)|UniProtKB:P37023, Pro-378, CHEBI:30006 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026802 20080301 PRO:CNA PR:000000336 serine/threonine-protein kinase receptor R3 sequence variant E379K (human) hACVRL1/var:E379K|serine/threonine-protein kinase receptor R3 sequence variant 27 (human)|UniProtKB:P37023, Glu-379, CHEBI:29967 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723|PMID:15712270 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026803 20080301 PRO:CNA PR:000000337 serine/threonine-protein kinase receptor R3 sequence variant M376R (human) hACVRL1/var:M376R|serine/threonine-protein kinase receptor R3 sequence variant 28 (human)|UniProtKB:P37023, Met-376, CHEBI:29952 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:8640225 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006212 20080301 PRO:CNA PR:000000338 serine/threonine-protein kinase receptor R3 sequence variant D397G (human) hACVRL1/var:D397G|serine/threonine-protein kinase receptor R3 sequence variant 29 (human)|UniProtKB:P37023, Asp-397, CHEBI:29947 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026804 20080301 PRO:CNA PR:000000339 serine/threonine-protein kinase receptor R3 sequence variant C51Y (human) hACVRL1/var:C51Y|serine/threonine-protein kinase receptor R3 sequence variant 3 (human)|UniProtKB:P37023, Cys-51, CHEBI:46858 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11170071 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006205 20080301 PRO:CNA PR:000000340 serine/threonine-protein kinase receptor R3 sequence variant I398N (human) hACVRL1/var:I398N|serine/threonine-protein kinase receptor R3 sequence variant 30 (human)|UniProtKB:P37023, Ile-398, CHEBI:50347 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11170071 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026805 20080301 PRO:CNA PR:000000341 serine/threonine-protein kinase receptor R3 sequence variant W399S (human) hACVRL1/var:W399S|serine/threonine-protein kinase receptor R3 sequence variant 31 (human)|UniProtKB:P37023, Trp-399, CHEBI:29999 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11170071 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026806 20080301 PRO:CNA PR:000000342 serine/threonine-protein kinase receptor R3 sequence variant E407D (human) hACVRL1/var:E407D|serine/threonine-protein kinase receptor R3 sequence variant 32 (human)|UniProtKB:P37023, Glu-407, CHEBI:29958 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10767348|PMID:15712270 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026807 20080301 PRO:CNA PR:000000343 serine/threonine-protein kinase receptor R3 sequence variant R411P (human) hACVRL1/var:R411P|serine/threonine-protein kinase receptor R3 sequence variant 33 (human)|UniProtKB:P37023, Arg-411, CHEBI:50342 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026808 20080301 PRO:CNA PR:000000344 serine/threonine-protein kinase receptor R3 sequence variant R411Q (human) hACVRL1/var:R411Q|serine/threonine-protein kinase receptor R3 sequence variant 34 (human)|UniProtKB:P37023, Arg-411, CHEBI:30011 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682|PMID:15024723|PMID:8640225 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006213 20080301 PRO:CNA PR:000000344 serine/threonine-protein kinase receptor R3 sequence variant R411Q (human) hACVRL1/var:R411Q|serine/threonine-protein kinase receptor R3 sequence variant 34 (human)|UniProtKB:P37023, Arg-411, CHEBI:30011 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006213 20080301 PRO:CNA PR:000000344 serine/threonine-protein kinase receptor R3 sequence variant R411Q (human) hACVRL1/var:R411Q|serine/threonine-protein kinase receptor R3 sequence variant 34 (human)|UniProtKB:P37023, Arg-411, CHEBI:30011 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006213 20080301 PRO:CNA PR:000000345 serine/threonine-protein kinase receptor R3 sequence variant R411W (human) hACVRL1/var:R411W|serine/threonine-protein kinase receptor R3 sequence variant 35 (human)|UniProtKB:P37023, Arg-411, CHEBI:29954 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11484689|PMID:15024723|PMID:15712270 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026809 20080301 PRO:CNA PR:000000346 serine/threonine-protein kinase receptor R3 sequence variant P424T (human) hACVRL1/var:P424T|serine/threonine-protein kinase receptor R3 sequence variant 36 (human)|UniProtKB:P37023, Pro-424, CHEBI:30013 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:9245985 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006214 20080301 PRO:CNA PR:000000347 serine/threonine-protein kinase receptor R3 sequence variant F425L (human) hACVRL1/var:F425L|serine/threonine-protein kinase receptor R3 sequence variant 37 (human)|UniProtKB:P37023, Phe-425, CHEBI:30006 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026810 20080301 PRO:CNA PR:000000348 serine/threonine-protein kinase receptor R3 sequence variant F425V (human) hACVRL1/var:F425V|serine/threonine-protein kinase receptor R3 sequence variant 38 (human)|UniProtKB:P37023, Phe-425, CHEBI:30015 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15712270 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026811 20080301 PRO:CNA PR:000000349 serine/threonine-protein kinase receptor R3 sequence variant F425del (human) hACVRL1/var:F425del|serine/threonine-protein kinase receptor R3 sequence variant 39 (human)|UniProtKB:P37023, 22-423, 425-503 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia UniProtKB_VAR:VAR_026812 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026812 20080301 PRO:CNA PR:000000350 serine/threonine-protein kinase receptor R3 sequence variant R67Q (human) hACVRL1/var:R67Q|serine/threonine-protein kinase receptor R3 sequence variant 4 (human)|UniProtKB:P37023, Arg-67, CHEBI:30011 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682|PMID:9245985 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006206 20080301 PRO:CNA PR:000000350 serine/threonine-protein kinase receptor R3 sequence variant R67Q (human) hACVRL1/var:R67Q|serine/threonine-protein kinase receptor R3 sequence variant 4 (human)|UniProtKB:P37023, Arg-67, CHEBI:30011 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006206 20080301 PRO:CNA PR:000000350 serine/threonine-protein kinase receptor R3 sequence variant R67Q (human) hACVRL1/var:R67Q|serine/threonine-protein kinase receptor R3 sequence variant 4 (human)|UniProtKB:P37023, Arg-67, CHEBI:30011 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006206 20080301 PRO:CNA PR:000000351 serine/threonine-protein kinase receptor R3 sequence variant R479L (human) hACVRL1/var:R479L|serine/threonine-protein kinase receptor R3 sequence variant 40 (human)|UniProtKB:P37023, Arg-479, CHEBI:30006 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026813 20080301 PRO:CNA PR:000000352 serine/threonine-protein kinase receptor R3 sequence variant A482V (human) hACVRL1/var:A482V|serine/threonine-protein kinase receptor R3 sequence variant 41 (human)|UniProtKB:P37023, Ala-482, CHEBI:30015 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026814 20080301 PRO:CNA PR:000000353 serine/threonine-protein kinase receptor R3 sequence variant R484W (human) hACVRL1/var:R484W|serine/threonine-protein kinase receptor R3 sequence variant 42 (human)|UniProtKB:P37023, Arg-484, CHEBI:29954 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:11484689|PMID:15024723 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026815 20080301 PRO:CNA PR:000000354 serine/threonine-protein kinase receptor R3 sequence variant K487T (human) hACVRL1/var:K487T|serine/threonine-protein kinase receptor R3 sequence variant 43 (human)|UniProtKB:P37023, Lys-487, CHEBI:30013 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026816 20080301 PRO:CNA PR:000000354 serine/threonine-protein kinase receptor R3 sequence variant K487T (human) hACVRL1/var:K487T|serine/threonine-protein kinase receptor R3 sequence variant 43 (human)|UniProtKB:P37023, Lys-487, CHEBI:30013 located_in GO:0005886 plasma membrane PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026816 20080301 PRO:CNA PR:000000355 serine/threonine-protein kinase receptor R3 sequence variant GA48/49EP (human) hACVRL1/var:GA48/49EP|serine/threonine-protein kinase receptor R3 sequence variant 44 (human)|UniProtKB:P37023, Gly-48, CHEBI:29972|Ala-49, CHEBI:46217 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia UniProtKB_VAR:VAR_026784 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026784 20080301 PRO:CNA PR:000000356 serine/threonine-protein kinase receptor R3 sequence variant R67W (human) hACVRL1/var:R67W|serine/threonine-protein kinase receptor R3 sequence variant 5 (human)|UniProtKB:P37023, Arg-67, CHEBI:29954 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:15712270 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026786 20080301 PRO:CNA PR:000000357 serine/threonine-protein kinase receptor R3 sequence variant C77W (human) hACVRL1/var:C77W|serine/threonine-protein kinase receptor R3 sequence variant 6 (human)|UniProtKB:P37023, Cys-77, CHEBI:29954 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10694922|PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006207 20080301 PRO:CNA PR:000000357 serine/threonine-protein kinase receptor R3 sequence variant C77W (human) hACVRL1/var:C77W|serine/threonine-protein kinase receptor R3 sequence variant 6 (human)|UniProtKB:P37023, Cys-77, CHEBI:29954 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006207 20080301 PRO:CNA PR:000000357 serine/threonine-protein kinase receptor R3 sequence variant C77W (human) hACVRL1/var:C77W|serine/threonine-protein kinase receptor R3 sequence variant 6 (human)|UniProtKB:P37023, Cys-77, CHEBI:29954 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006207 20080301 PRO:CNA PR:000000358 serine/threonine-protein kinase receptor R3 sequence variant N96D (human) hACVRL1/var:N96D|serine/threonine-protein kinase receptor R3 sequence variant 7 (human)|UniProtKB:P37023, Asn-96, CHEBI:29958 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:10694922 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006208 20080301 PRO:CNA PR:000000359 serine/threonine-protein kinase receptor R3 sequence variant D179A (human) hACVRL1/var:D179A|serine/threonine-protein kinase receptor R3 sequence variant 8 (human)|UniProtKB:P37023, Asp-179, CHEBI:46217 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026787 20080301 PRO:CNA PR:000000359 serine/threonine-protein kinase receptor R3 sequence variant D179A (human) hACVRL1/var:D179A|serine/threonine-protein kinase receptor R3 sequence variant 8 (human)|UniProtKB:P37023, Asp-179, CHEBI:46217 located_in GO:0009986 cell surface PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026787 20080301 PRO:CNA PR:000000360 serine/threonine-protein kinase receptor R3 sequence variant G211D (human) hACVRL1/var:G211D|serine/threonine-protein kinase receptor R3 sequence variant 9 (human)|UniProtKB:P37023, Gly-211, CHEBI:29958 associated_with_disease_progression DOID:1270 hereditary hemorrhagic telangiectasia PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026788 20080301 PRO:CNA PR:000000360 serine/threonine-protein kinase receptor R3 sequence variant G211D (human) hACVRL1/var:G211D|serine/threonine-protein kinase receptor R3 sequence variant 9 (human)|UniProtKB:P37023, Gly-211, CHEBI:29958 located_in GO:0005783 endoplasmic reticulum PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026788 20080301 PRO:CNA PR:000000360 serine/threonine-protein kinase receptor R3 sequence variant G211D (human) hACVRL1/var:G211D|serine/threonine-protein kinase receptor R3 sequence variant 9 (human)|UniProtKB:P37023, Gly-211, CHEBI:29958 NOT enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:14684682 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026788 20080301 PRO:CNA PR:000000367 smad4 sequence variant E330G (human) hSMAD4/var:E330G|smad4 sequence variant 1 (human)|UniProtKB:Q13485, Glu-330, CHEBI:29947 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_022833 20080301 PRO:CNA PR:000000368 smad4 sequence variant G352R (human) hSMAD4/var:G352R|smad4 sequence variant 2 (human)|UniProtKB:Q13485, Gly-352, CHEBI:29952 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019571 20080301 PRO:CNA PR:000000368 smad4 sequence variant G352R (human) hSMAD4/var:G352R|smad4 sequence variant 2 (human)|UniProtKB:Q13485, Gly-352, CHEBI:29952 associated_with_disease_progression DOID:4905 pancreatic carcinoma PMID:12417513 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019571 20080301 PRO:CNA PR:000000369 smad4 sequence variant R361C (human) hSMAD4/var:R361C|smad4 sequence variant 3 (human)|UniProtKB:Q13485, Arg-361, CHEBI:29950 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:9811934 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019572 20080301 PRO:CNA PR:000000370 smad4 sequence variant G386D (human) hSMAD4/var:G386D|smad4 sequence variant 4 (human)|UniProtKB:Q13485, Gly-386, CHEBI:29958 associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:15031030 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019573 20080301 PRO:CNA PR:000000371 smad4 sequence variant D493H (human) hSMAD4/var:D493H|smad4 sequence variant 5 (human)|UniProtKB:Q13485, Asp-493, CHEBI:29979 associated_with_disease_progression DOID:4905 pancreatic carcinoma PMID:8553070 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011380 20080301 PRO:CNA PR:000000398 TGF-beta 1 sequence variant L10P (human) hTGFB1/var:L10P|TGF-beta 1 sequence variant 1 (human)|UniProtKB:P01137, Leu-10, CHEBI:50342 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:9783545 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_016171 20080301 PRO:CNA PR:000000399 TGF-beta 1 sequence variant T81H (human) hTGFB1/var:T81H|TGF-beta 1 sequence variant 2 (human)|UniProtKB:P01137, Tyr-81, CHEBI:29979 associated_with_disease_progression DOID:4997 Camurati-Engelmann disease PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000399 TGF-beta 1 sequence variant T81H (human) hTGFB1/var:T81H|TGF-beta 1 sequence variant 2 (human)|UniProtKB:P01137, Tyr-81, CHEBI:29979 has_agent SO:0001558 polypeptide_localization_variant PMID:11062463|PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000399 TGF-beta 1 sequence variant T81H (human) hTGFB1/var:T81H|TGF-beta 1 sequence variant 2 (human)|UniProtKB:P01137, Tyr-81, CHEBI:29979 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11062463 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000400 TGF-beta 1 sequence variant R218C (human) hTGFB1/var:R218C|TGF-beta 1 sequence variant 3 (human)|UniProtKB:P01137, Arg-218, CHEBI:29950 associated_with_disease_progression DOID:4997 Camurati-Engelmann disease PMID:10973241|PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000400 TGF-beta 1 sequence variant R218C (human) hTGFB1/var:R218C|TGF-beta 1 sequence variant 3 (human)|UniProtKB:P01137, Arg-218, CHEBI:29950 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000400 TGF-beta 1 sequence variant R218C (human) hTGFB1/var:R218C|TGF-beta 1 sequence variant 3 (human)|UniProtKB:P01137, Arg-218, CHEBI:29950 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000400 TGF-beta 1 sequence variant R218C (human) hTGFB1/var:R218C|TGF-beta 1 sequence variant 3 (human)|UniProtKB:P01137, Arg-218, CHEBI:29950 increased enables GO:0008083 growth factor activity PR:000002555 PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000401 TGF-beta 1 sequence variant R218H (human) hTGFB1/var:R218H|TGF-beta 1 sequence variant 4 (human)|UniProtKB:P01137, Arg-218, CHEBI:29979 associated_with_disease_progression DOID:4997 Camurati-Engelmann disease PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000402 TGF-beta 1 sequence variant H222D (human) hTGFB1/var:H222D|TGF-beta 1 sequence variant 5 (human)|UniProtKB:P01137, His-222, CHEBI:29958 associated_with_disease_progression DOID:4997 Camurati-Engelmann disease PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000402 TGF-beta 1 sequence variant H222D (human) hTGFB1/var:H222D|TGF-beta 1 sequence variant 5 (human)|UniProtKB:P01137, His-222, CHEBI:29958 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000402 TGF-beta 1 sequence variant H222D (human) hTGFB1/var:H222D|TGF-beta 1 sequence variant 5 (human)|UniProtKB:P01137, His-222, CHEBI:29958 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000403 TGF-beta 1 sequence variant C225R (human) hTGFB1/var:C225R|TGF-beta 1 sequence variant 6 (human)|UniProtKB:P01137, Cys-225, CHEBI:29952 associated_with_disease_progression DOID:4997 Camurati-Engelmann disease PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000403 TGF-beta 1 sequence variant C225R (human) hTGFB1/var:C225R|TGF-beta 1 sequence variant 6 (human)|UniProtKB:P01137, Cys-225, CHEBI:29952 located_in GO:0005615 extracellular space PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000403 TGF-beta 1 sequence variant C225R (human) hTGFB1/var:C225R|TGF-beta 1 sequence variant 6 (human)|UniProtKB:P01137, Cys-225, CHEBI:29952 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000403 TGF-beta 1 sequence variant C225R (human) hTGFB1/var:C225R|TGF-beta 1 sequence variant 6 (human)|UniProtKB:P01137, Cys-225, CHEBI:29952 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000403 TGF-beta 1 sequence variant C225R (human) hTGFB1/var:C225R|TGF-beta 1 sequence variant 6 (human)|UniProtKB:P01137, Cys-225, CHEBI:29952 increased enables GO:0008083 growth factor activity PR:000002555 PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000437 growth/differentiation factor 5 sequence variant C400Y (human) growth/differentiation factor 5 sequence variant 1 (human)|hGDF5/var:C400Y|UniProtKB:P43026, Cys-400, CHEBI:46858 associated_with_disease_progression DOID:0080052 acromesomelic dysplasia, Grebe type UniProtKB_VAR:VAR_017407 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017407 20080301 PRO:CNA PR:000000437 growth/differentiation factor 5 sequence variant C400Y (human) growth/differentiation factor 5 sequence variant 1 (human)|hGDF5/var:C400Y|UniProtKB:P43026, Cys-400, CHEBI:46858 enables GO:0005515 protein binding PR:000000164 PMID:9288098 IPI NCBITaxon:9606 UniProtKB_VAR:VAR_017407 20080301 PRO:CNA PR:000000437 growth/differentiation factor 5 sequence variant C400Y (human) growth/differentiation factor 5 sequence variant 1 (human)|hGDF5/var:C400Y|UniProtKB:P43026, Cys-400, CHEBI:46858 located_in GO:0005622 intracellular anatomical structure PMID:9288098 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017407 20080301 PRO:CNA PR:000000437 growth/differentiation factor 5 sequence variant C400Y (human) growth/differentiation factor 5 sequence variant 1 (human)|hGDF5/var:C400Y|UniProtKB:P43026, Cys-400, CHEBI:46858 NOT enables GO:0008083 growth factor activity PMID:9288098 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017407 20080301 PRO:CNA PR:000000438 growth/differentiation factor 5 sequence variant R438L (human) growth/differentiation factor 5 sequence variant 2 (human)|hGDF5/var:R438L|UniProtKB:P43026, Arg-438, CHEBI:30006 associated_with_disease_progression DOID:0050794 multiple synostoses syndrome PMID:16532400 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026545 20080301 PRO:CNA PR:000000438 growth/differentiation factor 5 sequence variant R438L (human) growth/differentiation factor 5 sequence variant 2 (human)|hGDF5/var:R438L|UniProtKB:P43026, Arg-438, CHEBI:30006 located_in GO:0005615 extracellular space PMID:16532400 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026545 20080301 PRO:CNA PR:000000439 growth/differentiation factor 5 sequence variant L441P (human) growth/differentiation factor 5 sequence variant 3 (human)|hGDF5/var:L441P|UniProtKB:P43026, Leu-441, CHEBI:50342 associated_with_disease_progression DOID:0050790 fibular hypoplasia and complex brachydactyly UniProtKB_VAR:VAR_017408 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017408 20080301 PRO:CNA PR:000000441 growth/differentiation factor 5 sequence variant 5 (mouse) mGDF5/var:5 associated_with_disease_progression MP:0006279 abnormal limb development PMID:8145850 EXP NCBITaxon:10090 20080301 PRO:CNA PR:000000452 lefty 2 sequence variant S342N (human) hLEFTY2/var:S342N|lefty 2 sequence variant 1 (human)|UniProtKB:O00292-1, Ser-342, CHEBI:50347 associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:10053005 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010385 20080301 PRO:CNA PR:000000470 smad2 sequence variant R133C (human) hSMAD2/var:R133C|smad2 sequence variant 1 (human)|UniProtKB:Q15796-1, Arg-133, CHEBI:29950 associated_with_disease_progression DOID:5672 large intestine cancer PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011375 20080301 PRO:CNA PR:000000470 smad2 sequence variant R133C (human) hSMAD2/var:R133C|smad2 sequence variant 1 (human)|UniProtKB:Q15796-1, Arg-133, CHEBI:29950 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011375 20080301 PRO:CNA PR:000000470 smad2 sequence variant R133C (human) hSMAD2/var:R133C|smad2 sequence variant 1 (human)|UniProtKB:Q15796-1, Arg-133, CHEBI:29950 NOT enables GO:0003713 transcription coactivator activity PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011375 20080301 PRO:CNA PR:000000471 smad2 sequence variant L440R (human) hSMAD2/var:L440R|smad2 sequence variant 2 (human)|UniProtKB:Q15796-1, Leu-440, CHEBI:29952 associated_with_disease_progression DOID:5672 large intestine cancer PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011377 20080301 PRO:CNA PR:000000472 smad2 sequence variant P445H (human) hSMAD2/var:P445H|smad2 sequence variant 3 (human)|UniProtKB:Q15796-1, Pro-445, CHEBI:29979 associated_with_disease_progression DOID:5672 large intestine cancer PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011378 20080301 PRO:CNA PR:000000472 smad2 sequence variant P445H (human) hSMAD2/var:P445H|smad2 sequence variant 3 (human)|UniProtKB:Q15796-1, Pro-445, CHEBI:29979 NOT enables GO:0003713 transcription coactivator activity PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011378 20080301 PRO:CNA PR:000000473 smad2 sequence variant D450E (human) hSMAD2/var:D450E|smad2 sequence variant 4 (human)|UniProtKB:Q15796-1, Asp-450, CHEBI:29972 associated_with_disease_progression DOID:5672 large intestine cancer PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011379 20080301 PRO:CNA PR:000000473 smad2 sequence variant D450E (human) hSMAD2/var:D450E|smad2 sequence variant 4 (human)|UniProtKB:Q15796-1, Asp-450, CHEBI:29972 NOT enables GO:0003713 transcription coactivator activity PMID:8752209 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011379 20080301 PRO:CNA PR:000000474 smad2 sequence variant 5 (human) hSMAD2/var:5|UniProtKB:Q15796-1, 2-343, 359-467 associated_with_disease_progression DOID:5672 large intestine cancer PMID:8673135 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011376 20080301 PRO:CNA PR:000000474 smad2 sequence variant 5 (human) hSMAD2/var:5|UniProtKB:Q15796-1, 2-343, 359-467 NOT enables GO:0003713 transcription coactivator activity PMID:8673135 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_011376 20080301 PRO:CNA PR:000000619 TGF-beta 1 sequence variant T81H cleaved 1 (human) hTGFB1/var:T81H/Clv:1|TGF-beta 1 sequence variant 2 cleaved 1 (human)|UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979 has_agent SO:0001558 polypeptide_localization_variant PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000620 TGF-beta 1 sequence variant T81H cleaved 2 (human) hTGFB1/var:T81H/Clv:2|TGF-beta 1 sequence variant 2 cleaved 2 (human)|UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979 located_in GO:0005615 extracellular space PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000621 TGF-beta 1 sequence variant R218C cleaved 1 (human) hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950 enables GO:0005160 transforming growth factor beta receptor binding PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000621 TGF-beta 1 sequence variant R218C cleaved 1 (human) hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950 enables GO:0042803 protein homodimerization activity PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000621 TGF-beta 1 sequence variant R218C cleaved 1 (human) hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950 located_in GO:0005615 extracellular space PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000621 TGF-beta 1 sequence variant R218C cleaved 1 (human) hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000621 TGF-beta 1 sequence variant R218C cleaved 1 (human) hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950 increased enables GO:0008083 growth factor activity PR:000000616 PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000622 TGF-beta 1 sequence variant R218C cleaved 2 (human) hTGFB1/var:R218C/Clv:2|TGF-beta 1 sequence variant 3 cleaved 2 (human)|UniProtKB:P01137, 30-278, Arg-218, CHEBI:29950 has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017608 20080301 PRO:CNA PR:000000623 TGF-beta 1 sequence variant H222D cleaved 1 (human) hTGFB1/var:H222D/Clv:1|TGF-beta 1 sequence variant 5 cleaved 1 (human)|UniProtKB:P01137, 279-390, His-222, CHEBI:29958 located_in GO:0005615 extracellular space PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000623 TGF-beta 1 sequence variant H222D cleaved 1 (human) hTGFB1/var:H222D/Clv:1|TGF-beta 1 sequence variant 5 cleaved 1 (human)|UniProtKB:P01137, 279-390, His-222, CHEBI:29958 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000623 TGF-beta 1 sequence variant H222D cleaved 1 (human) hTGFB1/var:H222D/Clv:1|TGF-beta 1 sequence variant 5 cleaved 1 (human)|UniProtKB:P01137, 279-390, His-222, CHEBI:29958 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000623 TGF-beta 1 sequence variant H222D cleaved 1 (human) hTGFB1/var:H222D/Clv:1|TGF-beta 1 sequence variant 5 cleaved 1 (human)|UniProtKB:P01137, 279-390, His-222, CHEBI:29958 increased enables GO:0008083 growth factor activity PR:000000616 PMID:12493741 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000624 TGF-beta 1 sequence variant H222D cleaved 2 (human) hTGFB1/var:H222D/Clv:2|TGF-beta 1 sequence variant 5 cleaved 2 (human)|UniProtKB:P01137, 30-278, His-222, CHEBI:29958 has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000624 TGF-beta 1 sequence variant H222D cleaved 2 (human) hTGFB1/var:H222D/Clv:2|TGF-beta 1 sequence variant 5 cleaved 2 (human)|UniProtKB:P01137, 30-278, His-222, CHEBI:29958 has_agent SO:0001601 conformational_change_variant PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017610 20080301 PRO:CNA PR:000000625 TGF-beta 1 sequence variant C225R cleaved 1 (human) hTGFB1/var:C225R/Clv:1|TGF-beta 1 sequence variant 6 cleaved 1 (human)|UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952 located_in GO:0005615 extracellular space PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000625 TGF-beta 1 sequence variant C225R cleaved 1 (human) hTGFB1/var:C225R/Clv:1|TGF-beta 1 sequence variant 6 cleaved 1 (human)|UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952 increased enables GO:0008083 growth factor activity PR:000000616 PMID:11062463|PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000626 TGF-beta 1 sequence variant C225R cleaved 2 (human) hTGFB1/var:C225R/Clv:2|TGF-beta 1 sequence variant 6 cleaved 2 (human)|UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952 has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017611 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 enables GO:0005160 transforming growth factor beta receptor binding PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 enables GO:0042803 protein homodimerization activity PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 located_in GO:0005615 extracellular space PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human) hTGFB1/var:R218H/Clv:1|TGF-beta 1 sequence variant 4 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979 increased enables GO:0008083 growth factor activity PR:000000616 PMID:12493741|PMID:12843182 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000628 TGF-beta 1 sequence variant R218H cleaved 2 (human) hTGFB1/var:R218H/Clv:2|TGF-beta 1 sequence variant 4 cleaved 2 (human)|UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979 has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000628 TGF-beta 1 sequence variant R218H cleaved 2 (human) hTGFB1/var:R218H/Clv:2|TGF-beta 1 sequence variant 4 cleaved 2 (human)|UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979 has_agent SO:0001601 conformational_change_variant PMID:11278244 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_017607 20080301 PRO:CNA PR:000000647 smad1 isoform 1 phosphorylated 1 BMP receptor-activated smad1|SMAD1/iso:1/Phos:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949 TAS 20080301 PRO:CNA PR:000000678 sodium leak channel NALCN CanIon|NALCN|VGCNL1|voltage gated channel-like protein 1 acts_upstream_of_or_within GO:0006811 monoatomic ion transport PIRSF:PIRSF038547 ISS PIRSF:PIRSF038547 PIRSF:PIRSF038547|UniProtKB:Q8BXR5|UniProtKB:Q8IZF0 20080601 PRO:CNA PR:000000678 sodium leak channel NALCN CanIon|NALCN|VGCNL1|voltage gated channel-like protein 1 contributes_to enables GO:0005216 monoatomic ion channel activity PIRSF:PIRSF038547 ISS PIRSF:PIRSF038547 PIRSF:PIRSF038547|UniProtKB:Q8BXR5|UniProtKB:Q8IZF0 20080601 PRO:CNA PR:000000682 voltage-gated potassium channel alpha subunit with PAS domain fam:Kchan_sub-a_PAS part_of GO:0008076 voltage-gated potassium channel complex PIRSF:PIRSF038287 ISS PIRSF:PIRSF038287 PIRSF:PIRSF038287 20080601 PRO:CNA PR:000000682 voltage-gated potassium channel alpha subunit with PAS domain fam:Kchan_sub-a_PAS contributes_to enables GO:0005249 voltage-gated potassium channel activity PIRSF:PIRSF038287 ISS PIRSF:PIRSF038287 PIRSF:PIRSF038287 20080601 PRO:CNA PR:000000684 voltage-gated potassium channel subunit KQT fam:Kchan_sub-KQT part_of GO:0008076 voltage-gated potassium channel complex PIRSF:PIRSF038513 ISS PIRSF:PIRSF038513 PIRSF:PIRSF038513 20080601 PRO:CNA PR:000000684 voltage-gated potassium channel subunit KQT fam:Kchan_sub-KQT contributes_to enables GO:0005249 voltage-gated potassium channel activity PIRSF:PIRSF038513 ISS PIRSF:PIRSF038513 PIRSF:PIRSF038513 20080601 PRO:CNA PR:000000685 voltage-gated potassium channel alpha subunit fam:Kchan_sub-a part_of GO:0008076 voltage-gated potassium channel complex PIRSF:PIRSF002449 ISS PIRSF:PIRSF002449 PIRSF:PIRSF002449 20080601 PRO:CNA PR:000000685 voltage-gated potassium channel alpha subunit fam:Kchan_sub-a contributes_to enables GO:0005249 voltage-gated potassium channel activity PIRSF:PIRSF002449 ISS PIRSF:PIRSF002449 PIRSF:PIRSF002449 20080601 PRO:CNA PR:000000701 modulatory voltage-gated potassium channel subunit KCNG fam:Kchan_sub-KCNG|silent subunit enables GO:0015459 potassium channel regulator activity PIRSF:PIRSF500980 ISS PIRSF:PIRSF500980 PIRSF:PIRSF500980 20080301 PRO:CNA PR:000000702 modulatory voltage-gated potassium channel subunit KCNS fam:Kchan_sub-KCNS|silent subunit enables GO:0015459 potassium channel regulator activity PIRSF:PIRSF500981 ISS PIRSF:PIRSF500981 PIRSF:PIRSF500981 20080301 PRO:CNA PR:000000724 voltage-gated potassium channel KCNF1 KCNF1|kH1|voltage-gated potassium channel subunit Kv5.1 enables GO:0015459 potassium channel regulator activity PMID:9696692 IDA UniProtKB:Q7TSH7|UniProtKB:Q9H3M0 20080601 PRO:CNA Note=The organism source is uncertain. PR:000000724 voltage-gated potassium channel KCNF1 KCNF1|kH1|voltage-gated potassium channel subunit Kv5.1 part_of GO:0008076 voltage-gated potassium channel complex PMID:9696692 IDA UniProtKB:Q7TSH7|UniProtKB:Q9H3M0 20080601 PRO:CNA Note=The organism source is uncertain. PR:000000724 voltage-gated potassium channel KCNF1 KCNF1|kH1|voltage-gated potassium channel subunit Kv5.1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9696692 IDA UniProtKB:Q7TSH7|UniProtKB:Q9H3M0 20080601 PRO:CNA Note=The organism source is uncertain. PR:000000725 voltage-gated potassium channel KCNV1 KCNV1|neuronal potassium channel alpha subunit HNKA|voltage-gated potassium channel subunit Kv8.1 enables GO:0015459 potassium channel regulator activity PANTHER:PTHR11537:SF38 ISS PANTHER:PTHR11537:SF38 PANTHER:PTHR11537:SF38|UniProtKB:Q6PIU1|UniProtKB:Q8BZN2 20080601 PRO:CNA PR:000000726 voltage-gated potassium channel KCNV2 KCNV2|voltage-gated potassium channel subunit Kv8.2 enables GO:0015459 potassium channel regulator activity PANTHER:PTHR11537:SF40 ISS PANTHER:PTHR11537:SF39 PANTHER:PTHR11537:SF39|UniProtKB:Q8CFS6|UniProtKB:Q8TDN2 20080601 PRO:CNA PR:000000738 cGMP-gated cation channel alpha-1 sequence variant S320F (human) cGMP-gated cation channel alpha-1 sequence variant 1 (human)|hCNGA1/var:S320F|UniProtKB:P29973-1, Ser-320, CHEBI:29997 associated_with_disease_progression DOID:10584 retinitis pigmentosa PMID:7479749 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009297 20080601 PRO:CNA PR:000000738 cGMP-gated cation channel alpha-1 sequence variant S320F (human) cGMP-gated cation channel alpha-1 sequence variant 1 (human)|hCNGA1/var:S320F|UniProtKB:P29973-1, Ser-320, CHEBI:29997 NOT located_in GO:0005886 plasma membrane PMID:7479749 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009297 20080601 PRO:CNA PR:000000741 cyclic nucleotide-gated cation channel alpha-3 sequence variant R283Q (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 1 (human)|hCNGA3/var:R283Q|UniProtKB:Q16281-1, Arg-283, CHEBI:30011 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010904 20080601 PRO:CNA PR:000000742 cyclic nucleotide-gated cation channel alpha-3 sequence variant T291R (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 2 (human)|hCNGA3/var:T291R|UniProtKB:Q16281-1, Thr-291, CHEBI:29952 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010906 20080601 PRO:CNA PR:000000743 cyclic nucleotide-gated cation channel alpha-3 sequence variant G557R (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 3 (human)|hCNGA3/var:G557R|UniProtKB:Q16281-1, Gly-557, CHEBI:29952 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010909 20080601 PRO:CNA PR:000000744 cyclic nucleotide-gated cation channel alpha-3 sequence variant V529M (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 4 (human)|hCNGA3/var:V529M|UniProtKB:Q16281-1, Val-529, CHEBI:16044 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010907 20080601 PRO:CNA PR:000000745 cyclic nucleotide-gated cation channel alpha-3 sequence variant R283W (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 5 (human)|hCNGA3/var:R283W|UniProtKB:Q16281-1, Arg-283, CHEBI:29954 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010905 20080601 PRO:CNA PR:000000746 cyclic nucleotide-gated cation channel alpha-3 sequence variant F547L (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 6 (human)|hCNGA3/var:F547L|UniProtKB:Q16281-1, Phe-547, CHEBI:30006 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010908 20080601 PRO:CNA PR:000000747 cyclic nucleotide-gated cation channel alpha-3 sequence variant R410W (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 7 (human)|hCNGA3/var:R410W|UniProtKB:Q16281-1, Arg-410, CHEBI:29954 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010910 20080601 PRO:CNA PR:000000748 cyclic nucleotide-gated cation channel alpha-3 sequence variant P163L (human) cyclic nucleotide-gated cation channel alpha-3 sequence variant 8 (human)|hCNGA3/var:P163L|UniProtKB:Q16281-1, Pro-163, CHEBI:30006 associated_with_disease_progression DOID:13911 achromatopsia PMID:9662398 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010903 20080601 PRO:CNA PR:000000752 cyclic nucleotide-gated cation channel beta-3 sequence variant S435F (human) cyclic nucleotide-gated cation channel beta-3 sequence variant 1 (human)|hCNGB3/var:S435F|UniProtKB:Q9NQW8-1, Ser-435, CHEBI:29997 associated_with_disease_progression DOID:13911 achromatopsia PMID:10888875|PMID:10958649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_018111 20080601 PRO:CNA PR:000000759 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant D553N (human) hHCN4/var:D553N|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 1 (human)|UniProtKB:Q9Y3Q4, Asp-553, CHEBI:50347 associated_with_disease_progression DOID:13884 sick sinus syndrome PMID:15123648 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026534 20080601 PRO:CNA PR:000000759 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant D553N (human) hHCN4/var:D553N|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 1 (human)|UniProtKB:Q9Y3Q4, Asp-553, CHEBI:50347 NOT located_in GO:0005886 plasma membrane PMID:15123648 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026534 20080601 PRO:CNA PR:000000760 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant S672R (human) hHCN4/var:S672R|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 2 (human)|UniProtKB:Q9Y3Q4, Ser-672, CHEBI:29952 associated_with_disease_progression DOID:13884 sick sinus syndrome PMID:16407510 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026535 20080601 PRO:CNA PR:000000760 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant S672R (human) hHCN4/var:S672R|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 2 (human)|UniProtKB:Q9Y3Q4, Ser-672, CHEBI:29952 enables GO:0005222 intracellularly cAMP-activated cation channel activity PMID:16407510 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026535 20080601 PRO:CNA PR:000000760 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant S672R (human) hHCN4/var:S672R|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant 2 (human)|UniProtKB:Q9Y3Q4, Ser-672, CHEBI:29952 altered enables GO:0022843 voltage-gated monoatomic cation channel activity PR:000002604 PMID:16407510 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026535 20080601 PRO:CNA PR:000000803 voltage-gated potassium channel KCNV2 sequence variant G459D (human) hKCNV2/var:G459D|UniProtKB:Q8TDN2, Gly-459, CHEBI:29958|voltage-gated potassium channel KCNV2 sequence variant 1 (human) associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027637 20080601 PRO:CNA PR:000000804 voltage-gated potassium channel KCNV2 sequence variant A259V (human) hKCNV2/var:A259V|UniProtKB:Q8TDN2, Ala-259, CHEBI:30015|voltage-gated potassium channel KCNV2 sequence variant 2 (human) associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027635 20080601 PRO:CNA PR:000000805 voltage-gated potassium channel KCNV2 sequence variant L126Q (human) hKCNV2/var:L126Q|UniProtKB:Q8TDN2, Leu-126, CHEBI:30011|voltage-gated potassium channel KCNV2 sequence variant 3 (human) associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027632 20080601 PRO:CNA PR:000000806 voltage-gated potassium channel KCNV2 sequence variant 4 (human) hKCNV2/var:4|UniProtKB:Q8TDN2, 1-338, 342-545 associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027636 20080601 PRO:CNA PR:000000807 voltage-gated potassium channel KCNV2 sequence variant S256W (human) hKCNV2/var:S256W|UniProtKB:Q8TDN2, Ser-256, CHEBI:29954|voltage-gated potassium channel KCNV2 sequence variant 5 (human) associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027634 20080601 PRO:CNA PR:000000808 voltage-gated potassium channel KCNV2 sequence variant W188C (human) hKCNV2/var:W188C|UniProtKB:Q8TDN2, Trp-188, CHEBI:29950|voltage-gated potassium channel KCNV2 sequence variant 6 (human) associated_with_disease_progression DOID:0050795 cone dystrophy PMID:16909397 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_027633 20080601 PRO:CNA PR:000000817 voltage-gated potassium channel subunit KCNQ1 sequence variant T587M (human) hKCNQ1/var:T587M|UniProtKB:P51787-1, Thr-587, CHEBI:16044|voltage-gated potassium channel subunit KCNQ1 sequence variant 1 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10024302|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008951 20080601 PRO:CNA PR:000000818 voltage-gated potassium channel subunit KCNQ1 sequence variant S373P (human) hKCNQ1/var:S373P|UniProtKB:P51787-1, Ser-373, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 10 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008127 20080601 PRO:CNA PR:000000819 voltage-gated potassium channel subunit KCNQ1 sequence variant R243C (human) hKCNQ1/var:R243C|UniProtKB:P51787-1, Arg-243, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 11 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10409658|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010933 20080601 PRO:CNA PR:000000819 voltage-gated potassium channel subunit KCNQ1 sequence variant R243C (human) hKCNQ1/var:R243C|UniProtKB:P51787-1, Arg-243, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 11 (human) altered enables GO:0005251 delayed rectifier potassium channel activity PR:000002622 PMID:10409658 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010933 20080601 PRO:CNA PR:000000820 voltage-gated potassium channel subunit KCNQ1 sequence variant D317N (human) hKCNQ1/var:D317N|UniProtKB:P51787-1, Asp-317, CHEBI:50347|voltage-gated potassium channel subunit KCNQ1 sequence variant 12 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9302275|PMID:9482580 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001534 20080601 PRO:CNA PR:000000821 voltage-gated potassium channel subunit KCNQ1 sequence variant V310I (human) hKCNQ1/var:V310I|UniProtKB:P51787-1, Val-310, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 13 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009926 20080601 PRO:CNA PR:000000822 voltage-gated potassium channel subunit KCNQ1 sequence variant S566F (human) hKCNQ1/var:S566F|UniProtKB:P51787-1, Ser-566, CHEBI:29997|voltage-gated potassium channel subunit KCNQ1 sequence variant 14 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009932 20080601 PRO:CNA PR:000000823 voltage-gated potassium channel subunit KCNQ1 sequence variant Y315C (human) hKCNQ1/var:Y315C|UniProtKB:P51787-1, Tyr-315, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 15 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9693036|PMID:9927399 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008946 20080601 PRO:CNA PR:000000824 voltage-gated potassium channel subunit KCNQ1 sequence variant S225L (human) hKCNQ1/var:S225L|UniProtKB:P51787-1, Ser-225, CHEBI:30006|voltage-gated potassium channel subunit KCNQ1 sequence variant 16 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9927399 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009923 20080601 PRO:CNA PR:000000825 voltage-gated potassium channel subunit KCNQ1 sequence variant A178P (human) hKCNQ1/var:A178P|UniProtKB:P51787-1, Ala-178, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 17 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001518 20080601 PRO:CNA PR:000000825 voltage-gated potassium channel subunit KCNQ1 sequence variant A178P (human) hKCNQ1/var:A178P|UniProtKB:P51787-1, Ala-178, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 17 (human) has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001518 20080601 PRO:CNA PR:000000825 voltage-gated potassium channel subunit KCNQ1 sequence variant A178P (human) hKCNQ1/var:A178P|UniProtKB:P51787-1, Ala-178, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 17 (human) NOT|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10704188|PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001518 20080601 PRO:CNA PR:000000826 voltage-gated potassium channel subunit KCNQ1 sequence variant A178T (human) hKCNQ1/var:A178T|UniProtKB:P51787-1, Ala-178, CHEBI:30013|voltage-gated potassium channel subunit KCNQ1 sequence variant 18 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9024139 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009920 20080601 PRO:CNA PR:000000827 voltage-gated potassium channel subunit KCNQ1 sequence variant G189R (human) hKCNQ1/var:G189R|UniProtKB:P51787-1, Gly-189, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 19 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001519 20080601 PRO:CNA PR:000000828 voltage-gated potassium channel subunit KCNQ1 sequence variant P448R (human) hKCNQ1/var:P448R|UniProtKB:P51787-1, Pro-448, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 2 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009931 20080601 PRO:CNA PR:000000829 voltage-gated potassium channel subunit KCNQ1 sequence variant T309R (human) hKCNQ1/var:T309R|UniProtKB:P51787-1, Thr-309, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 20 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001529 20080601 PRO:CNA PR:000000830 voltage-gated potassium channel subunit KCNQ1 sequence variant R591H (human) hKCNQ1/var:R591H|UniProtKB:P51787-1, Arg-591, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 21 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10024302|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008953 20080601 PRO:CNA PR:000000831 voltage-gated potassium channel subunit KCNQ1 sequence variant R366W (human) hKCNQ1/var:R366W|UniProtKB:P51787-1, Arg-366, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 22 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9693036 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008948 20080601 PRO:CNA PR:000000832 voltage-gated potassium channel subunit KCNQ1 sequence variant I313M (human) hKCNQ1/var:I313M|UniProtKB:P51787-1, Ile-313, CHEBI:16044|voltage-gated potassium channel subunit KCNQ1 sequence variant 23 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9024139 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001531 20080601 PRO:CNA PR:000000833 voltage-gated potassium channel subunit KCNQ1 sequence variant Y111C (human) hKCNQ1/var:Y111C|UniProtKB:P51787-1, Tyr-111, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 24 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009918 20080601 PRO:CNA PR:000000834 voltage-gated potassium channel subunit KCNQ1 sequence variant R533W (human) hKCNQ1/var:R533W|UniProtKB:P51787-1, Arg-533, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 25 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008949 20080601 PRO:CNA PR:000000834 voltage-gated potassium channel subunit KCNQ1 sequence variant R533W (human) hKCNQ1/var:R533W|UniProtKB:P51787-1, Arg-533, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 25 (human) altered enables GO:0005251 delayed rectifier potassium channel activity PR:000002622 PMID:10704188|PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008949 20080601 PRO:CNA PR:000000835 voltage-gated potassium channel subunit KCNQ1 sequence variant G168R (human) hKCNQ1/var:G168R|UniProtKB:P51787-1, Gly-168, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 26 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9693036 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001516 20080601 PRO:CNA PR:000000836 voltage-gated potassium channel subunit KCNQ1 sequence variant E261D (human) hKCNQ1/var:E261D|UniProtKB:P51787-1, Glu-261, CHEBI:29958|voltage-gated potassium channel subunit KCNQ1 sequence variant 27 (human) associated_with_disease_progression DOID:2842 Jervell-Lange Nielsen syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008944 20080601 PRO:CNA PR:000000837 voltage-gated potassium channel subunit KCNQ1 sequence variant A371T (human) hKCNQ1/var:A371T|UniProtKB:P51787-1, Ala-371, CHEBI:30013|voltage-gated potassium channel subunit KCNQ1 sequence variant 28 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001544 20080601 PRO:CNA PR:000000838 voltage-gated potassium channel subunit KCNQ1 sequence variant 29 (human) hKCNQ1/var:29|UniProtKB:P49747-1, 21-70, 74-757 associated_with_disease_progression DOID:2843 long QT syndrome PMID:10511610 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009917 20080601 PRO:CNA PR:000000839 voltage-gated potassium channel subunit KCNQ1 sequence variant A341V (human) hKCNQ1/var:A341V|UniProtKB:P51787-1, Ala-341, CHEBI:30015|voltage-gated potassium channel subunit KCNQ1 sequence variant 3 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:8818942|PMID:8872472|PMID:9570196 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001539 20080601 PRO:CNA PR:000000840 voltage-gated potassium channel subunit KCNQ1 sequence variant L250H (human) hKCNQ1/var:L250H|UniProtKB:P51787-1, Leu-250, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 30 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008943 20080601 PRO:CNA PR:000000841 voltage-gated potassium channel subunit KCNQ1 sequence variant S349W (human) hKCNQ1/var:S349W|UniProtKB:P51787-1, Ser-349, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 31 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009928 20080601 PRO:CNA PR:000000842 voltage-gated potassium channel subunit KCNQ1 sequence variant T391I (human) hKCNQ1/var:T391I|UniProtKB:P51787-1, Thr-391, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 32 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009930 20080601 PRO:CNA PR:000000843 voltage-gated potassium channel subunit KCNQ1 sequence variant K318N (human) hKCNQ1/var:K318N|UniProtKB:P51787-1, Lys-318, CHEBI:50347|voltage-gated potassium channel subunit KCNQ1 sequence variant 33 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9693036 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008947 20080601 PRO:CNA PR:000000844 voltage-gated potassium channel subunit KCNQ1 sequence variant A344V (human) hKCNQ1/var:A344V|UniProtKB:P51787-1, Ala-344, CHEBI:30015|voltage-gated potassium channel subunit KCNQ1 sequence variant 34 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001541 20080601 PRO:CNA PR:000000845 voltage-gated potassium channel subunit KCNQ1 sequence variant A525T (human) hKCNQ1/var:A525T|UniProtKB:P51787-1, Ala-525, CHEBI:30013|voltage-gated potassium channel subunit KCNQ1 sequence variant 35 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10482963|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009181 20080601 PRO:CNA PR:000000846 voltage-gated potassium channel subunit KCNQ1 sequence variant A341E (human) hKCNQ1/var:A341E|UniProtKB:P51787-1, Ala-341, CHEBI:29972|voltage-gated potassium channel subunit KCNQ1 sequence variant 36 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001538 20080601 PRO:CNA PR:000000846 voltage-gated potassium channel subunit KCNQ1 sequence variant A341E (human) hKCNQ1/var:A341E|UniProtKB:P51787-1, Ala-341, CHEBI:29972|voltage-gated potassium channel subunit KCNQ1 sequence variant 36 (human) associated_with_disease_progression MP:0003233 prolonged QT interval PMID:15498462 IMP NCBITaxon:10090 MGI_allele:3056651 20080601 PRO:CNA PR:000000847 voltage-gated potassium channel subunit KCNQ1 sequence variant R583C (human) hKCNQ1/var:R583C|UniProtKB:P51787-1, Arg-583, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 37 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009933 20080601 PRO:CNA PR:000000848 voltage-gated potassium channel subunit KCNQ1 sequence variant D242N (human) hKCNQ1/var:D242N|UniProtKB:P51787-1, Asp-242, CHEBI:50347|voltage-gated potassium channel subunit KCNQ1 sequence variant 38 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008940 20080601 PRO:CNA PR:000000849 voltage-gated potassium channel subunit KCNQ1 sequence variant L342F (human) hKCNQ1/var:L342F|UniProtKB:P51787-1, Leu-342, CHEBI:29997|voltage-gated potassium channel subunit KCNQ1 sequence variant 39 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001540 20080601 PRO:CNA PR:000000850 voltage-gated potassium channel subunit KCNQ1 sequence variant G306R (human) hKCNQ1/var:G306R|UniProtKB:P51787-1, Gly-306, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 4 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001528 20080601 PRO:CNA PR:000000851 voltage-gated potassium channel subunit KCNQ1 sequence variant S140G (human) hKCNQ1/var:S140G|UniProtKB:P51787-1, Ser-140, CHEBI:29947|voltage-gated potassium channel subunit KCNQ1 sequence variant 40 (human) associated_with_disease_progression DOID:0050650 familial atrial fibrillation PMID:12522251 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015742 20080601 PRO:CNA PR:000000851 voltage-gated potassium channel subunit KCNQ1 sequence variant S140G (human) hKCNQ1/var:S140G|UniProtKB:P51787-1, Ser-140, CHEBI:29947|voltage-gated potassium channel subunit KCNQ1 sequence variant 40 (human) has_agent SO:0001557 polypeptide_gain_of_function_variant PMID:12522251 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015742 20080601 PRO:CNA PR:000000851 voltage-gated potassium channel subunit KCNQ1 sequence variant S140G (human) hKCNQ1/var:S140G|UniProtKB:P51787-1, Ser-140, CHEBI:29947|voltage-gated potassium channel subunit KCNQ1 sequence variant 40 (human) increased enables GO:0005267 potassium channel activity PR:000002622 PMID:12522251 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_015742 20080601 PRO:CNA PR:000000852 voltage-gated potassium channel subunit KCNQ1 sequence variant G269S (human) hKCNQ1/var:G269S|UniProtKB:P51787-1, Gly-269, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 41 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009925 20080601 PRO:CNA PR:000000853 voltage-gated potassium channel subunit KCNQ1 sequence variant R555C (human) hKCNQ1/var:R555C|UniProtKB:P51787-1, Arg-555, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 42 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001545 20080601 PRO:CNA PR:000000854 voltage-gated potassium channel subunit KCNQ1 sequence variant R539W (human) hKCNQ1/var:R539W|UniProtKB:P51787-1, Arg-539, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 43 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008950 20080601 PRO:CNA PR:000000854 voltage-gated potassium channel subunit KCNQ1 sequence variant R539W (human) hKCNQ1/var:R539W|UniProtKB:P51787-1, Arg-539, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 43 (human) altered enables GO:0005251 delayed rectifier potassium channel activity PR:000002622 PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008950 20080601 PRO:CNA PR:000000854 voltage-gated potassium channel subunit KCNQ1 sequence variant R539W (human) hKCNQ1/var:R539W|UniProtKB:P51787-1, Arg-539, CHEBI:29954|voltage-gated potassium channel subunit KCNQ1 sequence variant 43 (human) altered part_of GO:0008076 voltage-gated potassium channel complex PR:000002622 PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008950 20080601 PRO:CNA PR:000000855 voltage-gated potassium channel subunit KCNQ1 sequence variant Y315S (human) hKCNQ1/var:Y315S|UniProtKB:P51787-1, Tyr-315, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 44 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144|PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001533 20080601 PRO:CNA PR:000000856 voltage-gated potassium channel subunit KCNQ1 sequence variant R174H (human) hKCNQ1/var:R174H|UniProtKB:P51787-1, Arg-174, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 45 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10367071 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008939 20080601 PRO:CNA PR:000000857 voltage-gated potassium channel subunit KCNQ1 sequence variant A194P (human) hKCNQ1/var:A194P|UniProtKB:P51787-1, Ala-194, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 46 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009922 20080601 PRO:CNA PR:000000858 voltage-gated potassium channel subunit KCNQ1 sequence variant Y184S (human) hKCNQ1/var:Y184S|UniProtKB:P51787-1, Tyr-184, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 47 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008125 20080601 PRO:CNA PR:000000859 voltage-gated potassium channel subunit KCNQ1 sequence variant G345E (human) hKCNQ1/var:G345E|UniProtKB:P51787-1, Gly-345, CHEBI:29972|voltage-gated potassium channel subunit KCNQ1 sequence variant 48 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001542 20080601 PRO:CNA PR:000000860 voltage-gated potassium channel subunit KCNQ1 sequence variant R190Q (human) hKCNQ1/var:R190Q|UniProtKB:P51787-1, Arg-190, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 49 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001520 20080601 PRO:CNA PR:000000860 voltage-gated potassium channel subunit KCNQ1 sequence variant R190Q (human) hKCNQ1/var:R190Q|UniProtKB:P51787-1, Arg-190, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 49 (human) has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:10704188|PMID:9482580 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001520 20080601 PRO:CNA PR:000000860 voltage-gated potassium channel subunit KCNQ1 sequence variant R190Q (human) hKCNQ1/var:R190Q|UniProtKB:P51787-1, Arg-190, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 49 (human) NOT part_of GO:0008076 voltage-gated potassium channel complex PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001520 20080601 PRO:CNA PR:000000860 voltage-gated potassium channel subunit KCNQ1 sequence variant R190Q (human) hKCNQ1/var:R190Q|UniProtKB:P51787-1, Arg-190, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 49 (human) NOT|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001520 20080601 PRO:CNA PR:000000861 voltage-gated potassium channel subunit KCNQ1 sequence variant T311I (human) hKCNQ1/var:T311I|UniProtKB:P51787-1, Thr-311, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 5 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9482580 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009927 20080601 PRO:CNA PR:000000862 voltage-gated potassium channel subunit KCNQ1 sequence variant G314S (human) hKCNQ1/var:G314S|UniProtKB:P51787-1, Gly-314, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 50 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:8872472|PMID:9693036 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001532 20080601 PRO:CNA PR:000000863 voltage-gated potassium channel subunit KCNQ1 sequence variant W248R (human) hKCNQ1/var:W248R|UniProtKB:P51787-1, Trp-248, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 51 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10409658 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008942 20080601 PRO:CNA PR:000000863 voltage-gated potassium channel subunit KCNQ1 sequence variant W248R (human) hKCNQ1/var:W248R|UniProtKB:P51787-1, Trp-248, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 51 (human) has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:10409658 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008942 20080601 PRO:CNA PR:000000863 voltage-gated potassium channel subunit KCNQ1 sequence variant W248R (human) hKCNQ1/var:W248R|UniProtKB:P51787-1, Trp-248, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 51 (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008942 20080601 PRO:CNA PR:000000863 voltage-gated potassium channel subunit KCNQ1 sequence variant W248R (human) hKCNQ1/var:W248R|UniProtKB:P51787-1, Trp-248, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 51 (human) altered|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PR:000002622 PMID:10409658 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008942 20080601 PRO:CNA PR:000000864 voltage-gated potassium channel subunit KCNQ1 sequence variant R366P (human) hKCNQ1/var:R366P|UniProtKB:P51787-1, Arg-366, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 52 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188|PMID:9024139 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001543 20080601 PRO:CNA PR:000000865 voltage-gated potassium channel subunit KCNQ1 sequence variant R366Q (human) hKCNQ1/var:R366Q|UniProtKB:P51787-1, Arg-366, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 53 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009929 20080601 PRO:CNA PR:000000866 voltage-gated potassium channel subunit KCNQ1 sequence variant E160K (human) hKCNQ1/var:E160K|UniProtKB:P51787-1, Glu-160, CHEBI:29967|voltage-gated potassium channel subunit KCNQ1 sequence variant 54 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009919 20080601 PRO:CNA PR:000000867 voltage-gated potassium channel subunit KCNQ1 sequence variant V254M (human) hKCNQ1/var:V254M|UniProtKB:P51787-1, Val-254, CHEBI:16044|voltage-gated potassium channel subunit KCNQ1 sequence variant 55 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001522 20080601 PRO:CNA PR:000000868 voltage-gated potassium channel subunit KCNQ1 sequence variant G345R (human) hKCNQ1/var:G345R|UniProtKB:P51787-1, Gly-345, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 56 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008126 20080601 PRO:CNA PR:000000869 voltage-gated potassium channel subunit KCNQ1 sequence variant E261K (human) hKCNQ1/var:E261K|UniProtKB:P51787-1, Glu-261, CHEBI:29967|voltage-gated potassium channel subunit KCNQ1 sequence variant 57 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10409658 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001523 20080601 PRO:CNA PR:000000869 voltage-gated potassium channel subunit KCNQ1 sequence variant E261K (human) hKCNQ1/var:E261K|UniProtKB:P51787-1, Glu-261, CHEBI:29967|voltage-gated potassium channel subunit KCNQ1 sequence variant 57 (human) NOT part_of GO:0008076 voltage-gated potassium channel complex PMID:8900283 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001523 20080601 PRO:CNA PR:000000869 voltage-gated potassium channel subunit KCNQ1 sequence variant E261K (human) hKCNQ1/var:E261K|UniProtKB:P51787-1, Glu-261, CHEBI:29967|voltage-gated potassium channel subunit KCNQ1 sequence variant 57 (human) NOT|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:8900283 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001523 20080601 PRO:CNA PR:000000870 voltage-gated potassium channel subunit KCNQ1 sequence variant V307L (human) hKCNQ1/var:V307L|UniProtKB:P51787-1, Val-307, CHEBI:30006|voltage-gated potassium channel subunit KCNQ1 sequence variant 58 (human) associated_with_disease_progression DOID:0050793 short QT syndrome PMID:15159330 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023841 20080601 PRO:CNA PR:000000870 voltage-gated potassium channel subunit KCNQ1 sequence variant V307L (human) hKCNQ1/var:V307L|UniProtKB:P51787-1, Val-307, CHEBI:30006|voltage-gated potassium channel subunit KCNQ1 sequence variant 58 (human) has_agent SO:0001557 polypeptide_gain_of_function_variant PMID:15159330 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023841 20080601 PRO:CNA PR:000000870 voltage-gated potassium channel subunit KCNQ1 sequence variant V307L (human) hKCNQ1/var:V307L|UniProtKB:P51787-1, Val-307, CHEBI:30006|voltage-gated potassium channel subunit KCNQ1 sequence variant 58 (human) increased enables GO:0005267 potassium channel activity PR:000002622 PMID:15159330 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_023841 20080601 PRO:CNA PR:000000871 voltage-gated potassium channel subunit KCNQ1 sequence variant F339del (human) deltaF339|hKCNQ1/var:F339del|UniProtKB:P49747-1, 21-338, 340-757|voltage-gated potassium channel subunit KCNQ1 sequence variant 59 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:15159330 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001537 20080601 PRO:CNA PR:000000872 voltage-gated potassium channel subunit KCNQ1 sequence variant R243H (human) hKCNQ1/var:R243H|UniProtKB:P51787-1, Arg-243, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 6 (human) associated_with_disease_progression DOID:2842 Jervell-Lange Nielsen syndrome PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008941 20080601 PRO:CNA PR:000000872 voltage-gated potassium channel subunit KCNQ1 sequence variant R243H (human) hKCNQ1/var:R243H|UniProtKB:P51787-1, Arg-243, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 6 (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008941 20080601 PRO:CNA PR:000000872 voltage-gated potassium channel subunit KCNQ1 sequence variant R243H (human) hKCNQ1/var:R243H|UniProtKB:P51787-1, Arg-243, CHEBI:29979|voltage-gated potassium channel subunit KCNQ1 sequence variant 6 (human) decreased|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PR:000002622 PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008941 20080601 PRO:CNA PR:000000873 voltage-gated potassium channel subunit KCNQ1 sequence variant G179S (human) hKCNQ1/var:G179S|UniProtKB:P51787-1, Gly-179, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 60 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10728423 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009921 20080601 PRO:CNA PR:000000874 voltage-gated potassium channel subunit KCNQ1 sequence variant A300T (human) hKCNQ1/var:A300T|UniProtKB:P51787-1, Ala-300, CHEBI:30013|voltage-gated potassium channel subunit KCNQ1 sequence variant 61 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9641694 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001526 20080601 PRO:CNA PR:000000874 voltage-gated potassium channel subunit KCNQ1 sequence variant A300T (human) hKCNQ1/var:A300T|UniProtKB:P51787-1, Ala-300, CHEBI:30013|voltage-gated potassium channel subunit KCNQ1 sequence variant 61 (human) contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9641694 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001526 20080601 PRO:CNA PR:000000875 voltage-gated potassium channel subunit KCNQ1 sequence variant R174C (human) hKCNQ1/var:R174C|UniProtKB:P51787-1, Arg-174, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 62 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001517 20080601 PRO:CNA PR:000000876 voltage-gated potassium channel subunit KCNQ1 sequence variant W305S (human) hKCNQ1/var:W305S|UniProtKB:P51787-1, Trp-305, CHEBI:29999|voltage-gated potassium channel subunit KCNQ1 sequence variant 63 (human) associated_with_disease_progression DOID:2842 Jervell-Lange Nielsen syndrome PMID:9781056 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001527 20080601 PRO:CNA PR:000000877 voltage-gated potassium channel subunit KCNQ1 sequence variant L266P (human) hKCNQ1/var:L266P|UniProtKB:P51787-1, Leu-266, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 64 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009924 20080601 PRO:CNA PR:000000878 voltage-gated potassium channel subunit KCNQ1 sequence variant R594Q (human) hKCNQ1/var:R594Q|UniProtKB:P51787-1, Arg-594, CHEBI:30011|voltage-gated potassium channel subunit KCNQ1 sequence variant 65 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009934 20080601 PRO:CNA PR:000000879 voltage-gated potassium channel subunit KCNQ1 sequence variant L273F (human) hKCNQ1/var:L273F|UniProtKB:P51787-1, Leu-273, CHEBI:29997|voltage-gated potassium channel subunit KCNQ1 sequence variant 66 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001525 20080601 PRO:CNA PR:000000879 voltage-gated potassium channel subunit KCNQ1 sequence variant L273F (human) hKCNQ1/var:L273F|UniProtKB:P51787-1, Leu-273, CHEBI:29997|voltage-gated potassium channel subunit KCNQ1 sequence variant 66 (human) has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001525 20080601 PRO:CNA PR:000000879 voltage-gated potassium channel subunit KCNQ1 sequence variant L273F (human) hKCNQ1/var:L273F|UniProtKB:P51787-1, Leu-273, CHEBI:29997|voltage-gated potassium channel subunit KCNQ1 sequence variant 66 (human) contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001525 20080601 PRO:CNA PR:000000880 voltage-gated potassium channel subunit KCNQ1 sequence variant Y281C (human) hKCNQ1/var:Y281C|UniProtKB:P51787-1, Tyr-281, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 67 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9927399 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008945 20080601 PRO:CNA PR:000000881 voltage-gated potassium channel subunit KCNQ1 sequence variant P320A (human) hKCNQ1/var:P320A|UniProtKB:P51787-1, Pro-320, CHEBI:46217|voltage-gated potassium channel subunit KCNQ1 sequence variant 68 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001535 20080601 PRO:CNA PR:000000882 voltage-gated potassium channel subunit KCNQ1 sequence variant F157C (human) hKCNQ1/var:F157C|UniProtKB:P51787-1, Phe-157, CHEBI:29950|voltage-gated potassium channel subunit KCNQ1 sequence variant 69 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220146 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008124 20080601 PRO:CNA PR:000000883 voltage-gated potassium channel subunit KCNQ1 sequence variant L353P (human) hKCNQ1/var:L353P|UniProtKB:P51787-1, Leu-353, CHEBI:50342|voltage-gated potassium channel subunit KCNQ1 sequence variant 7 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9693036 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_009180 20080601 PRO:CNA PR:000000884 voltage-gated potassium channel subunit KCNQ1 sequence variant G325R (human) hKCNQ1/var:G325R|UniProtKB:P51787-1, Gly-325, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 70 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9024139 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001536 20080601 PRO:CNA PR:000000885 voltage-gated potassium channel subunit KCNQ1 sequence variant W392R (human) hKCNQ1/var:W392R|UniProtKB:P51787-1, Trp-392, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 71 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10220144 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008128 20080601 PRO:CNA PR:000000886 voltage-gated potassium channel subunit KCNQ1 sequence variant G269D (human) hKCNQ1/var:G269D|UniProtKB:P51787-1, Gly-269, CHEBI:29958|voltage-gated potassium channel subunit KCNQ1 sequence variant 72 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001524 20080601 PRO:CNA PR:000000887 voltage-gated potassium channel subunit KCNQ1 sequence variant G589D (human) hKCNQ1/var:G589D|UniProtKB:P51787-1, Gly-589, CHEBI:29958|voltage-gated potassium channel subunit KCNQ1 sequence variant 73 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008952 20080601 PRO:CNA PR:000000888 voltage-gated potassium channel subunit KCNQ1 sequence variant G216R (human) hKCNQ1/var:G216R|UniProtKB:P51787-1, Gly-216, CHEBI:29952|voltage-gated potassium channel subunit KCNQ1 sequence variant 74 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:9272155 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001521 20080601 PRO:CNA PR:000000889 voltage-gated potassium channel subunit KCNQ1 sequence variant V417M (human) hKCNQ1/var:V417M|UniProtKB:P51787-1, Val-417, CHEBI:16044|voltage-gated potassium channel subunit KCNQ1 sequence variant 8 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10704188 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010934 20080601 PRO:CNA PR:000000890 voltage-gated potassium channel subunit KCNQ1 sequence variant T312I (human) hKCNQ1/var:T312I|UniProtKB:P51787-1, Thr-312, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 9 (human) associated_with_disease_progression DOID:2843 long QT syndrome PMID:10409658|PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001530 20080601 PRO:CNA PR:000000890 voltage-gated potassium channel subunit KCNQ1 sequence variant T312I (human) hKCNQ1/var:T312I|UniProtKB:P51787-1, Thr-312, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 9 (human) has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:10409658|PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001530 20080601 PRO:CNA PR:000000890 voltage-gated potassium channel subunit KCNQ1 sequence variant T312I (human) hKCNQ1/var:T312I|UniProtKB:P51787-1, Thr-312, CHEBI:30009|voltage-gated potassium channel subunit KCNQ1 sequence variant 9 (human) NOT|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10409658|PMID:9323054 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001530 20080601 PRO:CNA PR:000000907 voltage-gated potassium channel subunit KCNQ2 sequence variant S247W (human) hKCNQ2/var:S247W|UniProtKB:O43526-1, Ser-247, CHEBI:29954|voltage-gated potassium channel subunit KCNQ2 sequence variant 1 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:12742592 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026991 20080601 PRO:CNA PR:000000907 voltage-gated potassium channel subunit KCNQ2 sequence variant S247W (human) hKCNQ2/var:S247W|UniProtKB:O43526-1, Ser-247, CHEBI:29954|voltage-gated potassium channel subunit KCNQ2 sequence variant 1 (human) decreased enables GO:0005249 voltage-gated potassium channel activity PR:000002632 PMID:12742592 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026991 20080601 PRO:CNA PR:000000908 voltage-gated potassium channel subunit KCNQ2 sequence variant H228Q (human) hKCNQ2/var:H228Q|UniProtKB:O43526-1, His-228, CHEBI:30011|voltage-gated potassium channel subunit KCNQ2 sequence variant 10 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:14534157 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026989 20080601 PRO:CNA PR:000000909 voltage-gated potassium channel subunit KCNQ2 sequence variant R207W (human) hKCNQ2/var:R207W|UniProtKB:O43526-1, Arg-207, CHEBI:29954|voltage-gated potassium channel subunit KCNQ2 sequence variant 2 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:11572947 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026987 20080601 PRO:CNA PR:000000909 voltage-gated potassium channel subunit KCNQ2 sequence variant R207W (human) hKCNQ2/var:R207W|UniProtKB:O43526-1, Arg-207, CHEBI:29954|voltage-gated potassium channel subunit KCNQ2 sequence variant 2 (human) decreased enables GO:0005249 voltage-gated potassium channel activity PR:000002632 PMID:11572947 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026987 20080601 PRO:CNA PR:000000910 voltage-gated potassium channel subunit KCNQ2 sequence variant L243F (human) hKCNQ2/var:L243F|UniProtKB:O43526-1, Leu-243, CHEBI:29997|voltage-gated potassium channel subunit KCNQ2 sequence variant 3 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:14534157 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026990 20080601 PRO:CNA PR:000000911 voltage-gated potassium channel subunit KCNQ2 sequence variant 4 (human) hKCNQ2/var:4|UniProtKB:O43526-1, Arg-214, CHEBI:29954 associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:11175290 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010929 20080601 PRO:CNA PR:000000912 voltage-gated potassium channel subunit KCNQ2 sequence variant Y284C (human) hKCNQ2/var:Y284C|UniProtKB:O43526-1, Tyr-284, CHEBI:29950|voltage-gated potassium channel subunit KCNQ2 sequence variant 5 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:10788442 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010930 20080601 PRO:CNA PR:000000912 voltage-gated potassium channel subunit KCNQ2 sequence variant Y284C (human) hKCNQ2/var:Y284C|UniProtKB:O43526-1, Tyr-284, CHEBI:29950|voltage-gated potassium channel subunit KCNQ2 sequence variant 5 (human) located_in GO:0009986 cell surface PMID:10788442 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010930 20080601 PRO:CNA PR:000000913 voltage-gated potassium channel subunit KCNQ2 sequence variant A306T (human) hKCNQ2/var:A306T|UniProtKB:O43526-1, Ala-306, CHEBI:30013|voltage-gated potassium channel subunit KCNQ2 sequence variant 6 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:10788442 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010931 20080601 PRO:CNA PR:000000913 voltage-gated potassium channel subunit KCNQ2 sequence variant A306T (human) hKCNQ2/var:A306T|UniProtKB:O43526-1, Ala-306, CHEBI:30013|voltage-gated potassium channel subunit KCNQ2 sequence variant 6 (human) located_in GO:0009986 cell surface PMID:10788442 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010931 20080601 PRO:CNA PR:000000914 voltage-gated potassium channel subunit KCNQ2 sequence variant R333Q (human) hKCNQ2/var:R333Q|UniProtKB:O43526-1, Arg-333, CHEBI:30011|voltage-gated potassium channel subunit KCNQ2 sequence variant 7 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:14534157 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026992 20080601 PRO:CNA PR:000000915 voltage-gated potassium channel subunit KCNQ2 sequence variant M208V (human) hKCNQ2/var:M208V|UniProtKB:O43526-1, Met-208, CHEBI:30015|voltage-gated potassium channel subunit KCNQ2 sequence variant 8 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:14534157 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026988 20080601 PRO:CNA PR:000000916 voltage-gated potassium channel subunit KCNQ2 isoform 3 sequence variant K526N (human) hKCNQ2/iso:3/var:K526N|UniProtKB:O43526-3, Lys-526, CHEBI:50347|voltage-gated potassium channel subunit KCNQ2 sequence variant 9 (human) associated_with_disease_progression DOID:14264 benign neonatal seizures PMID:15249611 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_026993 20080601 PRO:CNA PR:000000920 voltage-gated potassium channel subunit KCNQ4 sequence variant G285C (human) hKCNQ4/var:G285C|UniProtKB:P56696-1, Gly-285, CHEBI:29950|voltage-gated potassium channel subunit KCNQ4 sequence variant 1 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10369879 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008727 20080601 PRO:CNA PR:000000920 voltage-gated potassium channel subunit KCNQ4 sequence variant G285C (human) hKCNQ4/var:G285C|UniProtKB:P56696-1, Gly-285, CHEBI:29950|voltage-gated potassium channel subunit KCNQ4 sequence variant 1 (human) altered enables GO:0005249 voltage-gated potassium channel activity PR:000000918 PMID:10369879 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008727 20080601 PRO:CNA PR:000000921 voltage-gated potassium channel subunit KCNQ4 sequence variant L274H (human) hKCNQ4/var:L274H|UniProtKB:P56696-1, Leu-274, CHEBI:29979|voltage-gated potassium channel subunit KCNQ4 sequence variant 2 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10925378 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010936 20080601 PRO:CNA PR:000000922 voltage-gated potassium channel subunit KCNQ4 sequence variant G285S (human) hKCNQ4/var:G285S|UniProtKB:P56696-1, Gly-285, CHEBI:29999|voltage-gated potassium channel subunit KCNQ4 sequence variant 3 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10025409 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001547 20080601 PRO:CNA PR:000000922 voltage-gated potassium channel subunit KCNQ4 sequence variant G285S (human) hKCNQ4/var:G285S|UniProtKB:P56696-1, Gly-285, CHEBI:29999|voltage-gated potassium channel subunit KCNQ4 sequence variant 3 (human) altered enables GO:0005249 voltage-gated potassium channel activity PR:000000918 PMID:10025409 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_001547 20080601 PRO:CNA PR:000000923 voltage-gated potassium channel subunit KCNQ4 sequence variant L281S (human) hKCNQ4/var:L281S|UniProtKB:P56696-1, Leu-281, CHEBI:29999|voltage-gated potassium channel subunit KCNQ4 sequence variant 4 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10571947 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010937 20080601 PRO:CNA PR:000000924 voltage-gated potassium channel subunit KCNQ4 sequence variant W276S (human) hKCNQ4/var:W276S|UniProtKB:P56696-1, Trp-276, CHEBI:29999|voltage-gated potassium channel subunit KCNQ4 sequence variant 5 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10369879 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008726 20080601 PRO:CNA PR:000000925 voltage-gated potassium channel subunit KCNQ4 sequence variant G321S (human) hKCNQ4/var:G321S|UniProtKB:P56696-1, Gly-321, CHEBI:29999|voltage-gated potassium channel subunit KCNQ4 sequence variant 6 (human) associated_with_disease_progression DOID:0050564 autosomal dominant nonsyndromic deafness PMID:10369879 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008728 20080601 PRO:CNA PR:000001030 erm protein enables GO:0008092 cytoskeletal protein binding PIRSF:PIRSF002305 ISS PIRSF:PIRSF002305 PIRSF:PIRSF002305 20080922 PRO:CNA PR:000001092 interleukin-17 fam:IL-17|IL17 acts_upstream_of_or_within GO:0019221 cytokine-mediated signaling pathway PIRSF:PIRSF003430 ISS PIRSF:PIRSF003430 PIRSF:PIRSF003430 20080922 PRO:CNA PR:000001124 calcium-independent alpha-latrotoxin receptor latrophilin acts_upstream_of_or_within GO:0007186 G protein-coupled receptor signaling pathway PIRSF:PIRSF010401 ISS PIRSF:PIRSF010401 PIRSF:PIRSF010401 20080915 PRO:CNA PR:000001124 calcium-independent alpha-latrotoxin receptor latrophilin acts_upstream_of_or_within GO:0017157 regulation of exocytosis PIRSF:PIRSF010401 ISS PIRSF:PIRSF010401 PIRSF:PIRSF010401 20080915 PRO:CNA PR:000002131 angiopoietin-1 receptor sequence variant R849W (human) angiopoietin-1 receptor sequence variant 1 (human)|hTEK/var:R849W|UniProtKB:Q02763-1, Arg-849, CHEBI:29954 associated_with_disease_progression DOID:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874|PMID:8980225 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_006352 20090309 PRO:CNA PR:000002131 angiopoietin-1 receptor sequence variant R849W (human) angiopoietin-1 receptor sequence variant 1 (human)|hTEK/var:R849W|UniProtKB:Q02763-1, Arg-849, CHEBI:29954 enables GO:0005515 protein binding PR:P27986-1 PMID:10369874 IPI NCBITaxon:9606 UniProtKB_VAR:VAR_006352 20090309 PRO:CNA Note=Binding to SH2 domain (PF00017) of p85 PR:000002132 angiopoietin-1 receptor sequence variant Y897S (human) angiopoietin-1 receptor sequence variant 2 (human)|hTEK/var:Y897S|UniProtKB:Q02763-1, Tyr-897, CHEBI:29999 associated_with_disease_progression DOID:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_008716 20090309 PRO:CNA PR:000002132 angiopoietin-1 receptor sequence variant Y897S (human) angiopoietin-1 receptor sequence variant 2 (human)|hTEK/var:Y897S|UniProtKB:Q02763-1, Tyr-897, CHEBI:29999 enables GO:0005515 protein binding PR:P27986-1 PMID:10369874 IPI NCBITaxon:9606 UniProtKB_VAR:VAR_008716 20090309 PRO:CNA Note=Binding to SH2 domain (PF00017) of p85 PR:000002173 zinc finger protein Helios isoform 1 IKZF2/iso:1|zinc finger protein Helios isoform B enables GO:0046982 protein heterodimerization activity PR:O08900|PR:Q03267-1 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 MGI:1342541 20090513 MGI:MGI PR:000002174 zinc finger protein Helios isoform 2 IKZF2/iso:2|zinc finger protein Helios isoform A enables GO:0046982 protein heterodimerization activity PR:P81183-1|PR:P81183-2 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 MGI:1342541 20111216 MGI:MGI PR:000002684 voltage-gated potassium channel subunit KCNA5 isoform 2 unmodified form KCNA5/iso:2/UnMod located_in GO:0005886 plasma membrane MGI_ref:63618|PMID:8226976 IC NCBITaxon:10090 GO:0005249 MGI:96662 20140425 MGI:MGI PR:000002988 zinc finger protein Eos isoform 1 IKZF4/iso:1 enables GO:0046982 protein heterodimerization activity PR:Q03267-1 MGI_ref:1333610|PMID:10218586 IPI NCBITaxon:10090 MGI:1343139 20090515 MGI:MGI PR:000002989 zinc finger protein Eos isoform 2 IKZF4/iso:2 enables GO:0042803 protein homodimerization activity PR:Q8C208-1 MGI_ref:1333610|PMID:10218586 IPI NCBITaxon:10090 MGI:1343139 20090515 MGI:MGI PR:000022012 nucleolar transcription factor 1 isoform UBF2 nucleolar transcription factor 1 isoform 2|nucleolar transcription factor 1 isoform short|UBTF/iso:UBF2 located_in GO:0005730 nucleolus MGI_ref:3836497|PMID:19103806 IDA NCBITaxon:10090 MGI:98512 20091215 MGI:MGI PR:000022012 nucleolar transcription factor 1 isoform UBF2 nucleolar transcription factor 1 isoform 2|nucleolar transcription factor 1 isoform short|UBTF/iso:UBF2 acts_upstream_of_or_within GO:0000183 rDNA heterochromatin formation MGI_ref:3836497|PMID:19103806 IMP NCBITaxon:10090 MGI:98512 20091215 MGI:MGI PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 DEGS2/iso:1 enables GO:0000170 sphingosine hydroxylase activity MGI_ref:3056825|PMID:15474011 IDA NCBITaxon:10090 MGI:1917309 20100202 MGI:MGI PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 DEGS2/iso:1 enables GO:0000170 sphingosine hydroxylase activity MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 MGI:1917309 20100202 MGI:MGI PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 DEGS2/iso:1 acts_upstream_of_or_within GO:0006667 sphinganine metabolic process MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 MGI:1917309 20100202 MGI:MGI PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 DEGS2/iso:1 acts_upstream_of_or_within GO:0046513 ceramide biosynthetic process MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 MGI:1917309 20100202 MGI:MGI PR:000024937 FUN30 homodimer (yeast) y(FUN30)*2 enables GO:0003677 DNA binding PMID:23779104 IDA NCBITaxon:559292 20141214 PRO:CNA PR:000024937 FUN30 homodimer (yeast) y(FUN30)*2 enables GO:0003682 chromatin binding PMID:23779104 IDA NCBITaxon:559292 20140114 PRO:CNA PR:000024937 FUN30 homodimer (yeast) y(FUN30)*2 enables GO:0004386 helicase activity PMID:23779104 IDA NCBITaxon:559292 20140114 PRO:CNA PR:000024937 FUN30 homodimer (yeast) y(FUN30)*2 enables GO:0008094 ATP-dependent activity, acting on DNA PMID:23779104 IDA NCBITaxon:559292 20140114 PRO:CNA PR:000024937 FUN30 homodimer (yeast) y(FUN30)*2 acts_upstream_of_or_within GO:0140751 histone octamer slider activity PMID:23779104 IDA NCBITaxon:559292 20140114 PRO:CNA revised 2022-07-14 by PRO:DAN since original activity GO:0042766 "nucleosome mobilization" was made obsolete. PR:000025509 synapsin-1 isoform 1b SYN1 isoform 2|SYN1/iso:1b|synapsin-1 isoform 2|synapsin-1 isoform Ib enables GO:0005515 protein binding PR:P04925 MGI_ref:2153789|PMID:11571277 IPI NCBITaxon:10090 MGI:98460 20100415 MGI:MGI PR:000025560 amyloid-beta precursor protein sequence variant D678N (human) hAPP/var:D678N|Tottori APP|UniProtKB:P05067-1, Asp-678, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:15201367|UniProtKB_VAR:VAR_044424 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_044424 20120412 PRO:DAN PR:000025561 amyloid-beta precursor protein sequence variant A692G (human) Flemish APP|hAPP/var:A692G|UniProtKB:P05067-1, Ala-692, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:11311152|PMID:1303239|PMID:9754958|UniProtKB_VAR:VAR_000016 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000016 20120412 PRO:DAN PR:000025562 amyloid-beta precursor protein sequence variant E693G (human) Arctic APP|hAPP/var:E693G|UniProtKB:P05067-1, Glu-693, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:11528419|PMID:1415269|UniProtKB_VAR:VAR_014215 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_014215 20120412 PRO:DAN PR:000025563 amyloid-beta precursor protein sequence variant E693K (human) hAPP/var:E693K|Italian APP|UniProtKB:P05067-1, Glu-693, CHEBI:29967 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy UniProtKB_VAR:VAR_014216 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_014216 20120412 PRO:DAN PR:000025564 amyloid-beta precursor protein sequence variant E693Q (human) Dutch APP|hAPP/var:E693Q|UniProtKB:P05067-1, Glu-693, CHEBI:30011 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy PMID:2111584|UniProtKB_VAR:VAR_000017 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000017 20120412 PRO:DAN PR:000025565 amyloid-beta precursor protein sequence variant D694N (human) hAPP/var:D694N|Iowa APP|UniProtKB:P05067-1, Asp-694, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-d694n-iowa EXP NCBITaxon:9606 Alzforum:app-d694n-iowa 20180510 PRO:DAN PR:000025565 amyloid-beta precursor protein sequence variant D694N (human) hAPP/var:D694N|Iowa APP|UniProtKB:P05067-1, Asp-694, CHEBI:50347 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy PMID:11409420|PMID:12654973|UniProtKB_VAR:VAR_014217 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_014217 20120412 PRO:DAN PR:000025566 amyloid-beta precursor protein sequence variant L705V (human) hAPP/var:L705V|UniProtKB:P05067-1, Leu-705, CHEBI:30015 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy PMID:16178030|UniProtKB_VAR:VAR_032276 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_032276 20120412 PRO:DAN PR:000025567 amyloid-beta precursor protein sequence variant A713T (human) hAPP/var:A713T|UniProtKB:P05067-1, Ala-713, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:1303275|PMID:15365148|UniProtKB_VAR:VAR_000019 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000019 20120412 PRO:DAN PR:000025567 amyloid-beta precursor protein sequence variant A713T (human) hAPP/var:A713T|UniProtKB:P05067-1, Ala-713, CHEBI:30013 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy Alzforum:app-a713t EXP NCBITaxon:9606 Alzforum:app-a713t 20180510 PRO:DAN PR:000025568 amyloid-beta precursor protein sequence variant T714A (human) hAPP/var:T714A|Iranian APP|UniProtKB:P05067-1, Thr-714, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:12034808|UniProtKB_VAR:VAR_032277 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_032277 20120412 PRO:DAN PR:000025569 amyloid-beta precursor protein sequence variant T714I (human) Austrian APP|hAPP/var:T714I|UniProtKB:P05067-1, Thr-714, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:11063718|PMID:15668448|UniProtKB_VAR:VAR_014218 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_014218 20120412 PRO:DAN PR:000025570 amyloid-beta precursor protein sequence variant V715M (human) French APP|hAPP/var:V715M|UniProtKB:P05067-1, Val-715, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:10097173|UniProtKB_VAR:VAR_010108 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010108 20120412 PRO:DAN PR:000025571 amyloid-beta precursor protein sequence variant I716V (human) Florida APP|hAPP/var:I716V|UniProtKB:P05067-1, Ile-716, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:9328472|UniProtKB_VAR:VAR_000020 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000020 20120412 PRO:DAN PR:000025572 amyloid-beta precursor protein sequence variant V717F (human) hAPP/var:V717F|Indiana APP|UniProtKB:P05067-1, Val-717, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:1925564|PMID:8267572|PMID:8290042|PMID:8476439|UniProtKB_VAR:VAR_000023 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000023 20120412 PRO:DAN PR:000025573 amyloid-beta precursor protein sequence variant V717G (human) hAPP/var:V717G|UniProtKB:P05067-1, Val-717, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:1944558|PMID:8476439|UniProtKB_VAR:VAR_000022 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000022 20120412 PRO:DAN PR:000025574 amyloid-beta precursor protein sequence variant V717I (human) hAPP/var:V717I|London APP|UniProtKB:P05067-1, Val-717, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:10631141|PMID:1671712|PMID:1678058|PMID:1908231|PMID:8267572|PMID:8476439|PMID:8577393|UniProtKB_VAR:VAR_000021 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000021 20120412 PRO:DAN PR:000025575 amyloid-beta precursor protein sequence variant V717L (human) hAPP/var:V717L|UniProtKB:P05067-1, Val-717, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:10867787|UniProtKB_VAR:VAR_014219 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_014219 20120412 PRO:DAN PR:000025576 amyloid-beta precursor protein sequence variant L723P (human) Australian APP|hAPP/var:L723P|UniProtKB:P05067-1, Leu-723, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:10665499|UniProtKB_VAR:VAR_010109 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010109 20120412 PRO:DAN PR:000025591 amyloid-beta precursor protein sequence variant A673T (human) hAPP/var:A673T|Icelandic APP|UniProtKB:P05067-1, Ala-673, CHEBI:30013 associated_with_disease_suppression DOID:10652 Alzheimer's disease Alzforum:app-a673t-icelandic EXP NCBITaxon:9606 Alzforum:app-a673t-icelandic 20180510 PRO:DAN PR:000025594 amyloid-beta precursor protein sequence variant V715A (human) German APP|hAPP/var:V715A|UniProtKB:P05067-1, Val-715, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-v715a-german EXP NCBITaxon:9606 Alzforum:app-v715a-german 20180510 PRO:DAN PR:000025595 amyloid-beta precursor protein sequence variant I716F (human) hAPP/var:I716F|Iberian APP|UniProtKB:P05067-1, Ile-716, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-i716f-iberian EXP NCBITaxon:9606 Alzforum:app-i716f-iberian 20180510 PRO:DAN PR:000025596 amyloid-beta precursor protein sequence variant I716T (human) hAPP/var:I716T|UniProtKB:P05067-1, Ile-716, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-i716t EXP NCBITaxon:9606 Alzforum:app-i716t 20180510 PRO:DAN PR:000025597 amyloid-beta precursor protein sequence variant T719P (human) hAPP/var:T719P|UniProtKB:P05067-1, Thr-719, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-t719p EXP NCBITaxon:9606 Alzforum:app-t719p 20180510 PRO:DAN PR:000025598 amyloid-beta precursor protein sequence variant K724N (human) Belgian APP|hAPP/var:K724N|UniProtKB:P05067-1, Lys-724, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-k724n-belgian EXP NCBITaxon:9606 Alzforum:app-k724n-belgian 20180510 PRO:DAN PR:000025599 amyloid-beta precursor protein sequence variant E682K (human) hAPP/var:E682K|Leuven APP|UniProtKB:P05067-1, Glu-682, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-e682k-leuven EXP NCBITaxon:9606 Alzforum:app-e682k-leuven 20180510 PRO:DAN PR:000025601 amyloid-beta precursor protein sequence variant KM670/671NL (human) hAPP/var:KM670/671NL|Swedish APP|UniProtKB:P05067-1, Lys-670, CHEBI:50347|Met-671, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease UniProtKB_VAR:VAR_000015 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_000015 20120412 PRO:DAN PR:000025602 amyloid-beta precursor protein sequence variant E693del (human) APP deltaGlu693|APP E693delta|hAPP/var:E693del|Osaka APP|UniProtKB:P05067-1, 1-692, 694-770 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-e693del-osaka EXP NCBITaxon:9606 Alzforum:app-e693del-osaka 20180510 PRO:DAN PR:000025633 mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 (human) hMED28/iso:1/Phos:1|UniProtKB:Q9H204-1, Tyr-64, MOD:00048 enables GO:0005515 protein binding PR:P62993 PMID:16899217 IPI NCBITaxon:9606 UniProtKB:Q9H204-1 20100510 PRO:JAN PR:000025637 G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human) hCCNE1/iso:3/Phos:1|UniProtKB:P24864-3, Ser-384, MOD:00046 enables GO:0005515 protein binding PR:Q13526 PMID:16223725 IPI NCBITaxon:9606 UniProtKB:P24864-3 20100510 PRO:JAN PR:000025639 platelet endothelial aggregation receptor 1 isoform 1 phosphorylated 1 (human) hPEAR1/iso:1/Phos:1|UniProtKB:Q5VY43-1, Tyr-925, MOD:00048|Ser-953/Ser-1029, MOD:00046 enables GO:0005515 protein binding PR:P29353 PMID:15851471 IPI NCBITaxon:9606 UniProtKB:Q5VY43-1 20100515 PRO:CNA PR:000025639 platelet endothelial aggregation receptor 1 isoform 1 phosphorylated 1 (human) hPEAR1/iso:1/Phos:1|UniProtKB:Q5VY43-1, Tyr-925, MOD:00048|Ser-953/Ser-1029, MOD:00046 enables GO:0005515 protein binding PR:P98077 PMID:15851471 IPI NCBITaxon:9606 UniProtKB:Q5VY43-1 20100515 PRO:CNA PR:000025639 platelet endothelial aggregation receptor 1 isoform 1 phosphorylated 1 (human) hPEAR1/iso:1/Phos:1|UniProtKB:Q5VY43-1, Tyr-925, MOD:00048|Ser-953/Ser-1029, MOD:00046 located_in GO:0009986 cell surface PMID:15851471 EXP NCBITaxon:9606 UniProtKB:Q5VY43-1 20100515 PRO:CNA PR:000025641 E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 (human) hSIAH1/iso:1/Phos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048 acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process PMID:16230351 EXP NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20100515 PRO:CNA PR:000025641 E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 (human) hSIAH1/iso:1/Phos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048 acts_upstream_of_or_within GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351 EXP NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20100515 PRO:CNA PR:000025641 E3 ubiquitin-protein ligase SIAH1 isoform 1 phosphorylated 1 (human) hSIAH1/iso:1/Phos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, MOD:00048 increased enables GO:0005515 protein binding PR:000045369 PR:Q69ZI1-1 PMID:16230351 IPI NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20151105 PRO:CNA PR:000025712 alpha-actinin-1 isoform 1 phosphorylated 1 (human) hACTN1/iso:1/Phos:1|UniProtKB:P12814-1, Tyr-12, MOD:00048 enables GO:0005515 protein binding PR:P12931 PMID:16291744 IPI NCBITaxon:9606 UniProtKB:P12814-1 20100520 PRO:JAN PR:000025712 alpha-actinin-1 isoform 1 phosphorylated 1 (human) hACTN1/iso:1/Phos:1|UniProtKB:P12814-1, Tyr-12, MOD:00048 enables GO:0019903 protein phosphatase binding PR:P18031 PMID:16291744 IPI NCBITaxon:9606 UniProtKB:P12814-1 20100520 PRO:JAN PR:000025712 alpha-actinin-1 isoform 1 phosphorylated 1 (human) hACTN1/iso:1/Phos:1|UniProtKB:P12814-1, Tyr-12, MOD:00048 acts_upstream_of_or_within GO:0016477 cell migration PMID:16291744 EXP NCBITaxon:9606 UniProtKB:P12814-1 20100520 PRO:JAN PR:000025714 B-cell lymphoma/leukemia 10 isoform 1 phosphorylated 1 (human) hBCL10/iso:1/Phos:1|UniProtKB:O95999-1, Ser-218/Ser-231, MOD:00046 enables GO:0005515 protein binding PR:P20749 PMID:16280327 IPI NCBITaxon:9606 UniProtKB:O95999-1 20100520 PRO:JAN PR:000025714 B-cell lymphoma/leukemia 10 isoform 1 phosphorylated 1 (human) hBCL10/iso:1/Phos:1|UniProtKB:O95999-1, Ser-218/Ser-231, MOD:00046 located_in GO:0005634 nucleus PMID:16280327 EXP NCBITaxon:9606 UniProtKB:O95999-1 20100520 PRO:JAN PR:000025714 B-cell lymphoma/leukemia 10 isoform 1 phosphorylated 1 (human) hBCL10/iso:1/Phos:1|UniProtKB:O95999-1, Ser-218/Ser-231, MOD:00046 part_of GO:0032996 Bcl3-Bcl10 complex PMID:16280327 EXP NCBITaxon:9606 UniProtKB:P20749 UniProtKB:O95999-1 20100520 PRO:JAN PR:000025723 heat shock factor protein 1 isoform Long phosphorylated 1 (human) hHSF1/iso:Long/Phos:1|UniProtKB:Q00613-1, Ser-121, MOD:00046 enables GO:0005515 protein binding PR:P07900 PMID:16278218 IPI NCBITaxon:9606 UniProtKB:Q00613-1 20100520 PRO:JAN PR:000025723 heat shock factor protein 1 isoform Long phosphorylated 1 (human) hHSF1/iso:Long/Phos:1|UniProtKB:Q00613-1, Ser-121, MOD:00046 enables GO:0005515 protein binding PR:P08238 PMID:16278218 IPI NCBITaxon:9606 UniProtKB:Q00613-1 20100520 PRO:JAN PR:000025723 heat shock factor protein 1 isoform Long phosphorylated 1 (human) hHSF1/iso:Long/Phos:1|UniProtKB:Q00613-1, Ser-121, MOD:00046 NOT enables GO:0000976 transcription cis-regulatory region binding PMID:16278218 EXP NCBITaxon:9606 UniProtKB:Q00613-1 20150820 PRO:JAN PR:000025725 heat shock factor protein 1 isoform Long phosphorylated 2 (human) hHSF1/iso:Long/Phos:2|UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P62258 PMID:12917326 IPI NCBITaxon:9606 UniProtKB:Q00613-1 20150504 PRO:CNA PR:000025725 heat shock factor protein 1 isoform Long phosphorylated 2 (human) hHSF1/iso:Long/Phos:2|UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046 located_in GO:0005737 cytoplasm PMID:12917326 IDA NCBITaxon:9606 UniProtKB:Q00613-1 20150504 PRO:CNA PR:000025727 Bcl-2-like protein 11 isoform 1 phosphorylated 1 (human) hBCL2L11/iso:1/Phos:1|UniProtKB:O43521-1, Ser-87, MOD:00046 enables GO:0005515 protein binding PR:P31946 PMID:16282323 IPI NCBITaxon:9606 UniProtKB:O43521-1 20100520 PRO:JAN PR:000025727 Bcl-2-like protein 11 isoform 1 phosphorylated 1 (human) hBCL2L11/iso:1/Phos:1|UniProtKB:O43521-1, Ser-87, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:16282323 EXP NCBITaxon:9606 UniProtKB:O43521-1 20100520 PRO:JAN PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 enables GO:0005515 protein binding PR:P20248 PMID:17254966 IPI NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 enables GO:0005515 protein binding PR:P24385 PMID:17254966 IPI NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 enables GO:0005515 protein binding PR:P24864 PMID:17254966 IPI NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 enables GO:0044877 protein-containing complex binding PR:000026741 PMID:17254966 IPI NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 acts_upstream_of_or_within GO:0051318 G1 phase PMID:17254966 EXP NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025750 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human) hCDKN1B/iso:1/Phos:2|UniProtKB:P46527-1, Tyr-88, MOD:00048 decreased enables GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PR:000045370 PMID:17254966 EXP NCBITaxon:9606 UniProtKB:P46527-1 20100710 PRO:CNA PR:000025763 interferon regulatory factor 3 isoform 1 phosphorylated 1 (human) hIRF3/iso:1/Phos:1|IRF3-P (human)|UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046 enables GO:0005515 protein binding PR:O14980 PMID:10805757 IPI NCBITaxon:9606 Reactome:REACT_7149 20110513 PRO:CNA Evidence=Fig4f PR:000025763 interferon regulatory factor 3 isoform 1 phosphorylated 1 (human) hIRF3/iso:1/Phos:1|IRF3-P (human)|UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046 located_in GO:0005829 cytosol Reactome:REACT_7149 EXP NCBITaxon:9606 UniProtKB:Q14653-1 20100718 PRO:CNA PR:000025765 IRF3-P:IRF3-P complex (human) located_in GO:0005634 nucleus PMID:10805757 EXP NCBITaxon:9606 Reactome:REACT_7444 20110513 PRO:CNA PR:000025765 IRF3-P:IRF3-P complex (human) located_in GO:0005654 nucleoplasm Reactome:REACT_7444 EXP NCBITaxon:9606 Reactome:REACT_7444 20100718 PRO:CNA PR:000025765 IRF3-P:IRF3-P complex (human) located_in GO:0005829 cytosol Reactome:REACT_7146 EXP NCBITaxon:9606 Reactome:REACT_7146 20100718 PRO:CNA PR:000025765 IRF3-P:IRF3-P complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140428 PRO:VS PR:000025765 IRF3-P:IRF3-P complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000025765 IRF3-P:IRF3-P complex (human) acts_upstream_of_or_within GO:0034340 response to type I interferon PMID:10805757 EXP NCBITaxon:9606 Reactome:REACT_7444 20110513 PRO:CNA PR:000025765 IRF3-P:IRF3-P complex (human) acts_upstream_of_or_within GO:0002753 cytoplasmic pattern recognition receptor signaling pathway Reactome:REACT_7146 EXP NCBITaxon:9606 20140428 PRO:VS PR:000025773 lipopolysaccharide receptor complex 3 (human) h(LPSR:3)|TLR4:MD2:LPS:CD14 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20150513 PRO:CNA PR:000025780 CD3 gamma isoform 1, signal peptide removed phosphorylated 1 (human) CD3 gamma with phosphorylated ITAM (human)|hCD3G/iso:1/SigPep-/Phos:1|PRO_0000014615, Tyr-160/Tyr-171, MOD:00048|UniProtKB:P09693-1, 23-182, Tyr-160/Tyr-171, MOD:00048 located_in GO:0005886 plasma membrane Reactome:REACT_13072 EXP NCBITaxon:9606 UniProtKB:P09693-1 20100718 PRO:CNA PR:000025782 CD3 epsilon:CD3 gamma with phosphorylated ITAM (human) h(CD3E:CD3G) located_in GO:0005886 plasma membrane Reactome:REACT_13214 EXP NCBITaxon:9606 Reactome:REACT_13214 20100718 PRO:CNA PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) hLY96/iso:1/SigPep-/NGlyco:1|MD-2 glycosylated|PRO_0000018619, Asn-26/Asn-114, MOD:00160|UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160 enables GO:0001530 lipopolysaccharide binding PMID:17569869 EXP NCBITaxon:9606 UniProtKB:Q9Y6Y9-1 20140514 PRO:CNA Occurs_in=PR:000025773. PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) hLY96/iso:1/SigPep-/NGlyco:1|MD-2 glycosylated|PRO_0000018619, Asn-26/Asn-114, MOD:00160|UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160 enables GO:1990458 lipooligosaccharide binding PMID:19783674 EXP NCBITaxon:9606 UniProtKB:Q9Y6Y9-1 20140814 PRO:CNA Target=lipooligosaccharide (CHEBI:35371). PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) hLY96/iso:1/SigPep-/NGlyco:1|MD-2 glycosylated|PRO_0000018619, Asn-26/Asn-114, MOD:00160|UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160 located_in GO:0005615 extracellular space PMID:11593030 EXP NCBITaxon:9606 UniProtKB:Q9Y6Y9-1 20100718 PRO:CNA PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) hLY96/iso:1/SigPep-/NGlyco:1|MD-2 glycosylated|PRO_0000018619, Asn-26/Asn-114, MOD:00160|UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160 located_in GO:0005615 extracellular space PMID:19783674 EXP NCBITaxon:9606 UniProtKB:Q9Y6Y9-1 20140814 PRO:CNA PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) hLY96/iso:1/SigPep-/NGlyco:1|MD-2 glycosylated|PRO_0000018619, Asn-26/Asn-114, MOD:00160|UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160 located_in GO:0005886 plasma membrane Reactome:REACT_7660 EXP NCBITaxon:9606 UniProtKB:Q9Y6Y9-1 20130520 PRO:CNA PR:000025790 T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 (human) hCD28/iso:1/SigPep-/Phos:1|PRO_0000014652, Tyr-191, MOD:00048|UniProtKB:P10747-1, 19-220, Tyr-191, MOD:00048 located_in GO:0005886 plasma membrane Reactome:REACT_20178 EXP NCBITaxon:9606 UniProtKB:P10747-1 20100718 PRO:CNA PR:000025792 phospho CD28 homodimer (human) h(CD28/iso:1/SigPep-/Phos:1)*2 located_in GO:0005886 plasma membrane Reactome:REACT_20268 EXP NCBITaxon:9606 Reactome:REACT_20268 20100718 PRO:CNA PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human) hEIF3F/iso:1/Phos:1|UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047 part_of GO:0005852 eukaryotic translation initiation factor 3 complex PMID:19245811 EXP NCBITaxon:9606 UniProtKB:O00303-1 20100804 PRO:JAN PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human) hEIF3F/iso:1/Phos:1|UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047 acts_upstream_of_or_within GO:0017148 negative regulation of translation PMID:19245811 EXP NCBITaxon:9606 UniProtKB:O00303-1 20100804 PRO:JAN PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human) hEIF3F/iso:1/Phos:1|UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process PMID:19245811 EXP NCBITaxon:9606 UniProtKB:O00303-1 20100804 PRO:JAN PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human) hEIF3F/iso:1/Phos:1|UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047 increased enables GO:0031369 translation initiation factor binding PR:000025839 PR:P55884 PMID:19245811 IPI NCBITaxon:9606 UniProtKB:O00303-1 20100804 PRO:JAN PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse) mSYK/iso:1/Phos:1|UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048 enables GO:0019901 protein kinase binding PR:P09769 PMID:15536084 IPI NCBITaxon:10090 UniProtKB:P48025-1 20100804 PRO:JAN Note=SH2 domain (PF00017) of p85is involved in binding PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse) mSYK/iso:1/Phos:1|UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048 enables GO:0031625 ubiquitin protein ligase binding PR:P09769 PMID:15536084 IPI NCBITaxon:10090 UniProtKB:P48025-1 20100804 PRO:JAN PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse) mSYK/iso:1/Phos:1|UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048 enables GO:0043548 phosphatidylinositol 3-kinase binding PR:P27986 PMID:15536084 IPI NCBITaxon:10090 UniProtKB:P48025-1 20100804 PRO:JAN PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse) mSYK/iso:1/Phos:1|UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048 acts_upstream_of_or_within GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis PMID:15536084 EXP NCBITaxon:10090 UniProtKB:P48025-1 20100804 PRO:JAN PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human) hMDM4/iso:1/PhosUbiq:1|UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148 enables GO:0071889 14-3-3 protein binding PR:P27348 PMID:16511560 IPI NCBITaxon:9606 UniProtKB:O15151-1 20150504 PRO:JAN PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human) hMDM4/iso:1/PhosUbiq:1|UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148 enables GO:0071889 14-3-3 protein binding PR:P61981 PMID:16511572 IPI NCBITaxon:9606 UniProtKB:O15151-1 20150504 PRO:CNA PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human) hMDM4/iso:1/PhosUbiq:1|UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148 located_in GO:0005634 nucleus PMID:16511560 EXP NCBITaxon:9606 UniProtKB:O15151-1 20100804 PRO:JAN PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human) hMDM4/iso:1/PhosUbiq:1|UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148 acts_upstream_of_or_within GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator PMID:16511560 EXP NCBITaxon:9606 UniProtKB:O15151-1 20100804 PRO:JAN PR:000025873 glutaminase 1 tetramer (Escherichia coli K-12) enables GO:0004359 glutaminase activity PMID:18459799 EXP NCBITaxon:83333 20100921 PRO:CNA PR:000025874 glutaminase 1 tetramer (Bacillus subtilis subsp. subtilis str. 168) enables GO:0004359 glutaminase activity PMID:18459799 EXP NCBITaxon:1423 20100921 PRO:CNA PR:000025882 siroheme synthase cysG phosphorylated 1 (Salmonella typhimurium) cysG/Phos:1 (SALTM)|UniProtKB:P25924, Ser-128, MOD:00046 decreased enables GO:0043115 precorrin-2 dehydrogenase activity PR:000025884 PDB:1PJQ|PMID:14595395 EXP NCBITaxon:99287 UniProtKB:P25924-1 20100921 PRO:CNA Note=Strain information inferred from PDB sequence [PRO:DAN] PR:000025884 siroheme synthase cysG unmodified form (Salmonella typhimurium) cysG/UnMod (SALTM) enables GO:0043115 precorrin-2 dehydrogenase activity PDB:1PJQ|PMID:14595395 EXP NCBITaxon:99287 UniProtKB:P25924-1 20151104 PRO:CNA Note=Strain information inferred from PDB sequence [PRO:DAN] PR:000025892 transcription factor Jun isoform 1 phosphorylated 1 (mouse) mJUN/iso:1/Phos:1|UniProtKB:P05627-1, Ser-63/Ser-73, MOD:00046|MOD:00696 enables GO:0005515 protein binding PR:Q60739-1 PMID:20516211 IPI NCBITaxon:10090 UniProtKB:P05627-1 20100825 PRO:HJD PR:000025906 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-ptsH/iso:1/Phos:1|phosphocarrier protein HPr isoform 1 P-Ser-HPr (Escherichia coli K-12)|UniProtKB:P0AA04-1, His-15, MOD:00890 enables GO:0005515 protein binding PR:P0AC86 PMID:9334229 IPI NCBITaxon:83333 UniProtKB:P0AA04-1 20101005 PRO:CNA PR:000025906 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-ptsH/iso:1/Phos:1|phosphocarrier protein HPr isoform 1 P-Ser-HPr (Escherichia coli K-12)|UniProtKB:P0AA04-1, His-15, MOD:00890 enables GO:0009927 histidine phosphotransfer kinase activity PMID:12963714 EXP NCBITaxon:83333 UniProtKB:P0AA04-1 20100925 PRO:CNA PR:000025906 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-ptsH/iso:1/Phos:1|phosphocarrier protein HPr isoform 1 P-Ser-HPr (Escherichia coli K-12)|UniProtKB:P0AA04-1, His-15, MOD:00890 acts_upstream_of_or_within GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system PMID:12963714 EXP NCBITaxon:83333 UniProtKB:P0AA04-1 20100925 PRO:CNA PR:000025906 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-ptsH/iso:1/Phos:1|phosphocarrier protein HPr isoform 1 P-Ser-HPr (Escherichia coli K-12)|UniProtKB:P0AA04-1, His-15, MOD:00890 acts_upstream_of_or_within GO:0006109 regulation of carbohydrate metabolic process PMID:9334229 EXP NCBITaxon:83333 UniProtKB:P0AA04-1 20101005 PRO:CNA PR:000025907 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Bacillus subtilis subsp. subtilis str. 168) ptsH/iso:1/Phos:1 (BACSU)|UniProtKB:P08877-1, His-15, MOD:00890 enables GO:0009927 histidine phosphotransfer kinase activity PMID:14527945 EXP NCBITaxon:1423 UniProtKB:P08877-1 20100925 PRO:CNA PR:000025907 phosphocarrier protein HPr isoform 1 phosphorylated 1 (Bacillus subtilis subsp. subtilis str. 168) ptsH/iso:1/Phos:1 (BACSU)|UniProtKB:P08877-1, His-15, MOD:00890 acts_upstream_of_or_within GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system PMID:14527945 EXP NCBITaxon:1423 UniProtKB:P08877-1 20100925 PRO:CNA PR:000025921 protein max isoform short acetylated 1 (human) hMAX/iso:short/Ac:1|UniProtKB:P61244-2, Lys-57/Lys-144/Lys-145, MOD:00064 located_in GO:0005634 nucleus PMID:17217336 EXP NCBITaxon:9606 UniProtKB:P61244-2 20100925 PRO:CNA PR:000025924 Max homodimer acetylated 1 (human) h(MAX/iso:short/AcRes+)*2 located_in GO:0005634 nucleus PMID:17217336 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025924 Max homodimer acetylated 1 (human) h(MAX/iso:short/AcRes+)*2 NOT enables GO:0008134 transcription factor binding PR:Q13105 PMID:16126174 IPI NCBITaxon:9606 20101005 PRO:CNA PR:000025927 TGF-beta 1 isoform 1 mature form (human) hTGFB1/iso:1/mature|PRO_0000033763|UniProtKB:P01137-1, 279-390 enables GO:0042803 protein homodimerization activity PMID:3162913|PMID:8471846 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000025927 TGF-beta 1 isoform 1 mature form (human) hTGFB1/iso:1/mature|PRO_0000033763|UniProtKB:P01137-1, 279-390 located_in GO:0031012 extracellular matrix PMID:8294500 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000025927 TGF-beta 1 isoform 1 mature form (human) hTGFB1/iso:1/mature|PRO_0000033763|UniProtKB:P01137-1, 279-390 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8471846 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000025927 TGF-beta 1 isoform 1 mature form (human) hTGFB1/iso:1/mature|PRO_0000033763|UniProtKB:P01137-1, 279-390 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:9918798 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000025928 TGF-beta 1 isoform 1 mature form (mouse) mTGFB1/iso:1/mature|PRO_0000033767|UniProtKB:P04202-1, 279-390 enables GO:0005160 transforming growth factor beta receptor binding PMID:14764882 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:000025928 TGF-beta 1 isoform 1 mature form (mouse) mTGFB1/iso:1/mature|PRO_0000033767|UniProtKB:P04202-1, 279-390 located_in GO:0031012 extracellular matrix PMID:9008713 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:000025928 TGF-beta 1 isoform 1 mature form (mouse) mTGFB1/iso:1/mature|PRO_0000033767|UniProtKB:P04202-1, 279-390 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:000025929 TGF-beta 1 isoform 1 mature form (rat) PRO_0000033771|rTGFB1/iso:1/mature|UniProtKB:P17246-1, 279-390 located_in GO:0031012 extracellular matrix PMID:11907708 IDA NCBITaxon:10116 UniProtKB:P17246-1 20080301 PRO:CNA PR:000025930 TGF-beta 1 isoform 1 mature form (green monkey) GrMonkey-TGFB1/iso:1/mature|PRO_0000033761|UniProtKB:P09533-1, 279-390 enables GO:0042803 protein homodimerization activity PMID:3185545 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000025930 TGF-beta 1 isoform 1 mature form (green monkey) GrMonkey-TGFB1/iso:1/mature|PRO_0000033761|UniProtKB:P09533-1, 279-390 located_in GO:0031012 extracellular matrix PMID:3185545 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000025930 TGF-beta 1 isoform 1 mature form (green monkey) GrMonkey-TGFB1/iso:1/mature|PRO_0000033761|UniProtKB:P09533-1, 279-390 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:3185545 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000025933 smad2-smad4 protein complex 1 (human) h(pSMAD2:SMAD4):1 located_in GO:0005654 nucleoplasm Reactome:REACT_7382 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025933 smad2-smad4 protein complex 1 (human) h(pSMAD2:SMAD4):1 located_in GO:0005829 cytosol Reactome:REACT_7344 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025933 smad2-smad4 protein complex 1 (human) h(pSMAD2:SMAD4):1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209|PMID:8980228 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 enables GO:0003713 transcription coactivator activity PMID:9689110 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8980228|PMID:9346966 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 enables GO:0046332 SMAD binding PR:Q13485 PMID:9311995 IPI NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 located_in GO:0005634 nucleus PMID:9006934|PMID:9346966 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:15690394|PMID:9689110 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8752209|PMID:8980228|PMID:9346966 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209|PMID:8980228 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025934 smad2 isoform Long phosphorylated 1 (human) hSMAD2/iso:Long/Phos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PMID:9346966 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:12193595 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 enables GO:0003712 transcription coregulator activity PMID:12193595 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 enables GO:0046332 SMAD binding PR:Q13485 PMID:12193595 IPI NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 located_in GO:0005634 nucleus PMID:12193595|PMID:17074053 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12193595 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:12193595 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025935 smad2 isoform Long phosphorylated 2 (human) hSMAD2/iso:Long/Phos:2|UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PMID:12193595 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20101004 PRO:CNA PR:000025936 smad2 isoform Long phosphorylated 3 (human) hSMAD2/iso:Long/Phos:3|UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046 enables GO:0046332 SMAD binding PR:Q13485 PMID:11027280 IPI NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025936 smad2 isoform Long phosphorylated 3 (human) hSMAD2/iso:Long/Phos:3|UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046 located_in GO:0005737 cytoplasm PMID:11027280 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025936 smad2 isoform Long phosphorylated 3 (human) hSMAD2/iso:Long/Phos:3|UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:11027280 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025936 smad2 isoform Long phosphorylated 3 (human) hSMAD2/iso:Long/Phos:3|UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PMID:11027280 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025936 smad2 isoform Long phosphorylated 3 (human) hSMAD2/iso:Long/Phos:3|UniProtKB:Q15796-1, Ser-240/Ser-465/Ser-467, MOD:00046 NOT enables GO:0003713 transcription coactivator activity PMID:11027280 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025937 smad2 isoform Long phosphorylated 4 (human) hSMAD2/iso:Long/Phos:4|UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046 located_in GO:0005737 cytoplasm PMID:10197981 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025937 smad2 isoform Long phosphorylated 4 (human) hSMAD2/iso:Long/Phos:4|UniProtKB:Q15796-1, Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255, MOD:00046 NOT enables GO:0003713 transcription coactivator activity PMID:10197981 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000025938 smad2 isoform Short phosphorylated 1 (human) hSMAD2/iso:Short/Phos:1|UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046 enables GO:0003677 DNA binding PMID:14701940|PMID:9873005 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000025938 smad2 isoform Short phosphorylated 1 (human) hSMAD2/iso:Short/Phos:1|UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046 enables GO:0003700 DNA-binding transcription factor activity PMID:9873005 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000025938 smad2 isoform Short phosphorylated 1 (human) hSMAD2/iso:Short/Phos:1|UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046 enables GO:0003712 transcription coregulator activity PMID:14701940|PMID:9873005 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000025938 smad2 isoform Short phosphorylated 1 (human) hSMAD2/iso:Short/Phos:1|UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:9873005 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000025942 smad2 isoform Long phosphorylated 1 (mouse) mSMAD2/iso:Long/Phos:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046 enables GO:0003713 transcription coactivator activity PMID:15282343 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000025942 smad2 isoform Long phosphorylated 1 (mouse) mSMAD2/iso:Long/Phos:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046 enables GO:0046332 SMAD binding PR:P97471 PMID:11043574 IPI NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000025942 smad2 isoform Long phosphorylated 1 (mouse) mSMAD2/iso:Long/Phos:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046 located_in GO:0005634 nucleus PMID:11557747 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000025942 smad2 isoform Long phosphorylated 1 (mouse) mSMAD2/iso:Long/Phos:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:11262418 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000025942 smad2 isoform Long phosphorylated 1 (mouse) mSMAD2/iso:Long/Phos:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11262418 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000025943 smad2 isoform Short phosphorylated 1 (mouse) mSMAD2/iso:Short/Phos:1|UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046 enables GO:0003700 DNA-binding transcription factor activity PMID:15630024 IDA NCBITaxon:10090 UniProtKB:Q62432-2 20080301 PRO:CNA PR:000025943 smad2 isoform Short phosphorylated 1 (mouse) mSMAD2/iso:Short/Phos:1|UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15630024 IDA NCBITaxon:10090 UniProtKB:Q62432-2 20080301 PRO:CNA PR:000025944 smad2-smad4 protein complex 1 (mouse) m(SMAD2:SMAD4):1 located_in GO:0005634 nucleus PMID:12672795 EXP NCBITaxon:10090 20101005 PRO:CNA PR:000025944 smad2-smad4 protein complex 1 (mouse) m(SMAD2:SMAD4):1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12672795 EXP NCBITaxon:10090 20101005 PRO:CNA PR:000025946 smad2-smad4 protein complex 3 (human) h(SMAD2:SMAD4):3 located_in GO:0005634 nucleus PMID:12193595 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025946 smad2-smad4 protein complex 3 (human) h(SMAD2:SMAD4):3 acts_upstream_of_or_within GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway PMID:12193595 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025947 smad2-smad4 protein complex 4 (human) h(SMAD2:SMAD4):4 located_in GO:0005737 cytoplasm PMID:11027280 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025947 smad2-smad4 protein complex 4 (human) h(SMAD2:SMAD4):4 acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:11027280 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000025950 smad2-smad4-ski protein complex acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:10705283|PMID:15107821 EXP 20101005 PRO:CNA PR:000025951 smad2-smad4-ski protein complex 1 (human) located_in GO:0005634 nucleus PMID:10485843 EXP NCBITaxon:9606 20101005 PRO:CNA Note=Conflicting information with data for complex 2 PR:000025951 smad2-smad4-ski protein complex 1 (human) acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:10485843 EXP NCBITaxon:9606 20101005 PRO:CNA Note=Conflicting information with data for complex 2 PR:000025952 smad2-smad4-ski protein complex 2 (human) located_in GO:0005737 cytoplasm PMID:12732634 EXP NCBITaxon:9606 20101005 PRO:CNA Note=Conflicting information with data for complex 1 PR:000025952 smad2-smad4-ski protein complex 2 (human) acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:12732634 EXP NCBITaxon:9606 20101005 PRO:CNA Note=Conflicting information with data for complex 1 PR:000025958 mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human) hSMAD4/iso:1/MonoUbiq:2|UniProtKB:Q13485-1, Lys-519, MOD:01148 acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:19135894 EXP NCBITaxon:9606 UniProtKB:Q13485-1 20101005 PRO:CNA PR:000025958 mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human) hSMAD4/iso:1/MonoUbiq:2|UniProtKB:Q13485-1, Lys-519, MOD:01148 NOT enables GO:0046332 SMAD binding PMID:19135894 EXP NCBITaxon:9606 UniProtKB:Q13485-1 20101005 PRO:CNA PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hTGFBR1/iso:1/SigPep-/Phos:1|PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047|UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 enables GO:0005025 transforming growth factor beta receptor activity, type I PMID:7774578|PMID:8947046 IDA NCBITaxon:9606 UniProtKB:P36897-1 20090309 PRO:CNA PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hTGFBR1/iso:1/SigPep-/Phos:1|PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047|UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 located_in GO:0005886 plasma membrane PMID:8947046 IDA NCBITaxon:9606 UniProtKB:P36897-1 20090309 PRO:CNA PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hTGFBR1/iso:1/SigPep-/Phos:1|PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047|UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:7774578 IDA NCBITaxon:9606 UniProtKB:P36897-1 20090309 PRO:CNA PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hTGFBR1/iso:1/SigPep-/Phos:1|PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047|UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8242743 IDA NCBITaxon:9606 UniProtKB:P36897-1 20090309 PRO:CNA PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hTGFBR1/iso:1/SigPep-/Phos:1|PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047|UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 acts_upstream_of_or_within GO:0007181 transforming growth factor beta receptor complex assembly PMID:8947046 IDA NCBITaxon:9606 UniProtKB:P36897-1 20090309 PRO:CNA PR:000025981 ccap-HPr-Ser46-P-cre operator complex (Priestia megaterium) acts_upstream_of_or_within GO:0045013 carbon catabolite repression of transcription PMID:15369672 EXP NCBITaxon:1404 20101005 PRO:CNA PR:000025982 ccap-HPr-Ser46-P-cre operator complex (Bacillus subtilis subsp. subtilis str. 168) acts_upstream_of_or_within GO:0045013 carbon catabolite repression of transcription PMID:15885105 EXP NCBITaxon:1423 20101005 PRO:CNA PR:000026021 Max-binding protein MNT isoform 1 phosphorylated 1 (human) hMNT/iso:1/Phos:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:16103876 EXP NCBITaxon:9606 UniProtKB:Q99583-1 20101005 PRO:CNA PR:000026022 Max-binding protein MNT isoform 1 phosphorylated 1 (mouse) mMNT/iso:1/Phos:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:16103876 EXP NCBITaxon:10090 UniProtKB:O08789-1 20101005 PRO:CNA PR:000026022 Max-binding protein MNT isoform 1 phosphorylated 1 (mouse) mMNT/iso:1/Phos:1 NOT enables GO:0140297 DNA-binding transcription factor binding PR:Q62141 PMID:16103876 IPI NCBITaxon:10090 UniProtKB:O08789-1 20101005 PRO:CNA PR:000026023 mnt-msin3-hdac1 complex enables GO:0004407 histone deacetylase activity PMID:16103876 EXP NCBITaxon:10090 20101005 PRO:CNA PR:000026023 mnt-msin3-hdac1 complex enables GO:0045892 negative regulation of DNA-templated transcription PMID:16103876 EXP NCBITaxon:10090 20150820 PRO:CNA PR:000026023 mnt-msin3-hdac1 complex enables GO:0070888 E-box binding PMID:16103876 EXP NCBITaxon:10090 20101005 PRO:CNA PR:000026030 mnt-max complex (human) enables GO:0070888 E-box binding PMID:9184233 EXP NCBITaxon:9606 20101005 PRO:CNA PR:000026033 c-myc protein isoform 1 acetylated 1 (human) hMYC/iso:1/Ac:1|UniProtKB:P01106-1, Lys-143/Lys-157/Lys-275/Lys-317/Lys-323/Lys-371, MOD:00394 enables GO:0003700 DNA-binding transcription factor activity PMID:16126174 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026033 c-myc protein isoform 1 acetylated 1 (human) hMYC/iso:1/Ac:1|UniProtKB:P01106-1, Lys-143/Lys-157/Lys-275/Lys-317/Lys-323/Lys-371, MOD:00394 located_in GO:0005634 nucleus PMID:16126174 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026033 c-myc protein isoform 1 acetylated 1 (human) hMYC/iso:1/Ac:1|UniProtKB:P01106-1, Lys-143/Lys-157/Lys-275/Lys-317/Lys-323/Lys-371, MOD:00394 part_of GO:0005667 transcription factor complex PMID:16126174 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026035 Myc-max acetylated complex (human) enables GO:0008134 transcription factor binding PR:Q13105 PMID:16126174 IPI NCBITaxon:9606 20101005 PRO:CNA Evidence=Fig6. Evidence for max short isoform comes from cited sources PMID:15003254, PMID:9162900. PR:000026035 Myc-max acetylated complex (human) enables GO:0070888 E-box binding PMID:16126174 EXP NCBITaxon:9606 20101005 PRO:CNA Evidence=Fig6. Evidence for max short isoform comes from cited source PMID:9162900. PR:000026039 Myc-max complex 1 (human) enables GO:0070888 E-box binding PMID:15003254 EXP NCBITaxon:9606 20101005 PRO:CNA Evidence for max short isoform comes from cited source PMID:9162900. PR:000026046 mga-max complex (mouse) enables GO:0043565 sequence-specific DNA binding PMID:10601024 EXP NCBITaxon:10090 20101005 PRO:CNA Note=T-box DNA binding PR:000026046 mga-max complex (mouse) enables GO:0070888 E-box binding PMID:10601024 EXP NCBITaxon:10090 20101005 PRO:CNA PR:000026051 c-myc protein isoform 1 O-glycosylated 1 (human) hMYC/iso:1/OGlyco:1|UniProtKB:P01106-1, Thr-58, MOD:00806 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:11904304 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026051 c-myc protein isoform 1 O-glycosylated 1 (human) hMYC/iso:1/OGlyco:1|UniProtKB:P01106-1, Thr-58, MOD:00806 acts_upstream_of_or_within GO:0006357 regulation of transcription by RNA polymerase II PMID:11904304 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 located_in GO:0005634 nucleus PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 part_of GO:0005667 transcription factor complex PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 acts_upstream_of_or_within GO:0006357 regulation of transcription by RNA polymerase II PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 acts_upstream_of_or_within GO:0008283 cell population proliferation PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026052 c-myc protein isoform 1 phosphorylated 1 (mouse) mMYC/iso:1/Phos:1|UniProtKB:P01108-1, Ser-62, MOD:00046 acts_upstream_of_or_within GO:0006879 intracellular iron ion homeostasis PMID:11018017 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026053 c-myc protein isoform 1 phosphorylated 2 (mouse) mMYC/iso:1/Phos:2|UniProtKB:P01108-1, Thr-58, MOD:00047|Ser-62, MOD:00046 located_in GO:0005634 nucleus PMID:14563837|PMID:15503302 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:000026054 c-myc protein isoform 1 phosphorylated 2 (human) hMYC/iso:1/Phos:2|UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046 NOT enables GO:0003700 DNA-binding transcription factor activity PMID:7623799 EXP NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026055 c-myc protein isoform 1 phosphorylated 3 (human) hMYC/iso:1/Phos:3|UniProtKB:P01106-1, Ser-62/Ser-71, MOD:00046 located_in GO:0005634 nucleus PMID:12676581 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026055 c-myc protein isoform 1 phosphorylated 3 (human) hMYC/iso:1/Phos:3|UniProtKB:P01106-1, Ser-62/Ser-71, MOD:00046 acts_upstream_of_or_within GO:0045766 positive regulation of angiogenesis PMID:12676581 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:000026111 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human) hMCCC1/var:MCCA D532H associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 20101130 PRO:CNA Note=Severe form of disease. PR:000026111 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human) hMCCC1/var:MCCA D532H has_agent SO:0001630 splice_region_variant PMID:11181649 EXP NCBITaxon:9606 20101130 PRO:CNA PR:000026112 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human) hMCCC1/var:MCCA L437P|UniProtKB:Q96RQ3, Leu-437, CHEBI:50342 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012788 20101130 PRO:CNA Note=Severe form of disease. PR:000026112 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human) hMCCC1/var:MCCA L437P|UniProtKB:Q96RQ3, Leu-437, CHEBI:50342 has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012788 20101130 PRO:CNA PR:000026113 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA R385S (human) hMCCC1/var:MCCA R385S|UniProtKB:Q96RQ3, Arg-385, CHEBI:29999 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012787 20101130 PRO:CNA Note=Severe form of disease. PR:000026113 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA R385S (human) hMCCC1/var:MCCA R385S|UniProtKB:Q96RQ3, Arg-385, CHEBI:29999 has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012787 20101130 PRO:CNA PR:000026114 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human) hMCCC1/var:MCCA A289V|UniProtKB:Q96RQ3, Ala-289, CHEBI:30015 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012785 20101130 PRO:CNA Note=Mild form of disease PR:000026114 methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human) hMCCC1/var:MCCA A289V|UniProtKB:Q96RQ3, Ala-289, CHEBI:30015 has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012785 20101130 PRO:CNA PR:000026118 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB S173L (human) hMCCC2/var:MCCB S173L|UniProtKB:Q9HCC0-1, Ser-173, CHEBI:30006 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012795 20101130 PRO:CNA Note=Severe form of disease. PR:000026119 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB E99Q (human) hMCCC2/var:MCCB E99Q|UniProtKB:Q9HCC0-1, Glu-99, CHEBI:30011 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012792 20101130 PRO:CNA Note=Severe and mild forms of disease PR:000026120 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB V339M (human) hMCCC2/var:MCCB V339M|UniProtKB:Q9HCC0-1, Val-339, CHEBI:16044 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_012800 20101130 PRO:CNA Note=Severe form of disease PR:000026121 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB I437V (human) hMCCC2/var:MCCB I437V associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11181649 EXP NCBITaxon:9606 20101130 PRO:CNA Note=Mild form of disease PR:000026121 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB I437V (human) hMCCC2/var:MCCB I437V has_agent SO:0001569 cryptic_splice_site_variant PMID:11181649 EXP NCBITaxon:9606 20101130 PRO:CNA PR:000026122 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant D172fs (human) hMCCC2/var:D172fs|MCC beta D172fs (human)|MCCB D172fs (human)|UniProtKB:Q9HCC0, 1-172|UniProtKB:Q9HCC0-1, 1-172 associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11170888 EXP NCBITaxon:9606 20101130 PRO:CNA PR:000026123 methylcrotonoyl-CoA carboxylase beta chain, mitochondrial sequence variant MCCB IVS3+5G->T (human) hMCCC2/var:MCCB IVS3+5G->T associated_with_disease_progression DOID:0050710 3-methylcrotonyl-CoA carboxylase deficiency PMID:11170888 EXP NCBITaxon:9606 20101130 PRO:CNA PR:000026130 bacterial-type serine palmitoyltransferase complex (Sphingomonas paucimobilis) SPT complex (SPHPI) enables GO:0004758 serine C-palmitoyltransferase activity PMID:17559874 EXP NCBITaxon:13689 20101206 PRO:CNA PR:000026130 bacterial-type serine palmitoyltransferase complex (Sphingomonas paucimobilis) SPT complex (SPHPI) located_in GO:0005737 cytoplasm PMID:11279212|PMID:17559874 EXP NCBITaxon:13689 20150820 PRO:CNA PR:000026132 bacterial-type serine palmitoyltransferase complex (Rhizorhabdus wittichii RW1) SPT complex (SPHWW) enables GO:0004758 serine C-palmitoyltransferase activity PMID:17559874 EXP NCBITaxon:392499 20101206 PRO:CNA PR:000026132 bacterial-type serine palmitoyltransferase complex (Rhizorhabdus wittichii RW1) SPT complex (SPHWW) located_in GO:0005737 cytoplasm PMID:17559874 IC NCBITaxon:392499 20150820 PRO:CNA PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse) mBAD/iso:1/Phos:2|UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046 enables GO:0005515 protein binding PR:000003237 PMID:16403219 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20140903 PRO:KER PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse) mBAD/iso:1/Phos:2|UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046 enables GO:0005515 protein binding PR:P63101-1 PMID:10949026 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse) mBAD/iso:1/Phos:2|UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:10949026 EXP NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse) mBAD/iso:1/Phos:2|UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046 decreased enables GO:0005515 protein binding PR:000037809 PR:Q64373-1 PMID:16403219 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20140903 PRO:KER PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse) mBAD/iso:1/Phos:2|UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046 NOT enables GO:0005515 protein binding PR:Q07817-1 PMID:10949026 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat) rBAD/iso:1/Phos:3|UniProtKB:O35147-1, Ser-112, MOD:00046 enables GO:0019902 phosphatase binding PR:P63329 PMID:10195903 IPI NCBITaxon:10116 UniProtKB:O35147-1 20090918 PRO:JAN PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat) rBAD/iso:1/Phos:3|UniProtKB:O35147-1, Ser-112, MOD:00046 located_in GO:0005829 cytosol PMID:10195903 EXP NCBITaxon:10116 UniProtKB:O35147-1 20090918 PRO:JAN PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat) rBAD/iso:1/Phos:3|UniProtKB:O35147-1, Ser-112, MOD:00046 decreased enables GO:0005515 protein binding PR:000002843 PR:P53563-1 PMID:10195903 IPI NCBITaxon:10116 UniProtKB:O35147-1 20090918 PRO:JAN PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse) mBAD/iso:1/Phos:4|UniProtKB:Q61337-1, Thr-201, MOD:00047 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:14967141 EXP NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse) mBAD/iso:1/Phos:4|UniProtKB:Q61337-1, Thr-201, MOD:00047 decreased enables GO:0005515 protein binding PR:000002843 PR:Q64373-1 PMID:14967141 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000026136 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse) mBAD/iso:1/Phos:5|UniProtKB:Q61337-1, Ser-136, MOD:00046 enables GO:0005515 protein binding PR:P63101 PMID:12049737 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000026137 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse) mBAD/iso:1/Phos:6|UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046 acts_upstream_of_or_within GO:0051402 neuron apoptotic process PMID:12049737 EXP NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000026139 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse) mBAD/iso:1/Phos:8|UniProtKB:Q61337-1, Ser-155, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P61982 PMID:10880354 IPI NCBITaxon:10090 20101206 PRO:CNA Note=GST-BAD is mouse: Cell signaling #9294 pEBG-MBad DNA. Fig8 PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human) hBAD/iso:2/Phos:1|UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046 enables GO:0005829 cytosol PMID:16932738 EXP NCBITaxon:9606 UniProtKB:Q92934-1 20090810 PRO:JAN PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human) hBAD/iso:2/Phos:1|UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046 enables GO:0019902 phosphatase binding PR:Q08209 PMID:10195903 IPI NCBITaxon:9606 UniProtKB:Q92934-1 20090918 PRO:JAN PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human) hBAD/iso:2/Phos:1|UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P63101 PMID:16932738 IPI NCBITaxon:9606 UniProtKB:Q92934-1 20101206 PRO:JAN PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human) hBAD/iso:2/Phos:1|UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046 located_in GO:0005829 cytosol PMID:10195903 EXP NCBITaxon:9606 UniProtKB:Q92934-1 20090918 PRO:JAN PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human) hBAD/iso:2/Phos:1|UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046 decreased enables GO:0005515 protein binding PR:000002844 PR:Q07817-1 PMID:10195903 IPI NCBITaxon:9606 UniProtKB:Q92934-1 20090918 PRO:JAN PR:000026144 serine palmitoyltransferase complex core 1 (human) 3-oxosphinganine synthetase, acyl-CoA:serine C-2 acyltransferase decarboxylating (human)|SPT (human) enables GO:0004758 serine C-palmitoyltransferase activity PMID:19416851 EXP NCBITaxon:9606 20101206 PRO:CNA Evidence=Fig6. Evidence=7. PR:000026153 serine palmitoyltransferase complex 5 (human) increased enables GO:0004758 serine C-palmitoyltransferase activity PR:000026144 PMID:19416851 EXP NCBITaxon:9606 20101206 PRO:CNA Evidence=Fig6. Evidence=Fig7. Strong preference for C16-CoA substrate. PR:000026154 serine palmitoyltransferase complex 6 (human) increased enables GO:0004758 serine C-palmitoyltransferase activity PR:000026144 PMID:19416851 EXP NCBITaxon:9606 20101206 PRO:CNA Evidence=Fig6. Evidence=Fig7. Strong preference for C16-CoA substrate. PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse) mBAD/iso:1/Phos:1|UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046 enables GO:0005515 protein binding PR:P62258-1 PMID:10490655 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN Note=Binding between proteins from heterogeneous species PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse) mBAD/iso:1/Phos:1|UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046 enables GO:0005515 protein binding PR:Q07817-1 PMID:10949026 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse) mBAD/iso:1/Phos:1|UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046 enables GO:0005515 protein binding PR:Q9CQV8 PMID:10490655 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090810 PRO:JAN PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse) mBAD/iso:1/Phos:1|UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046 decreased enables GO:0005515 protein binding PR:000026136 PR:P63101 PMID:12049737 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000026169 bacterial-type serine palmitoyltransferase complex (Sphingobacterium multivorum) SPT complex (SPHMU) enables GO:0004758 serine C-palmitoyltransferase activity PMID:17557831|PMID:19564159 EXP NCBITaxon:28454 20101206 PRO:CNA PR:000026189 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (human) activated ERK1|activated MAPK3|hMAPK3/iso:1/Phos:1|UniProtKB:P27361-1, Thr-202, MOD:00047|Tyr-204, MOD:00048 enables GO:0004672 protein kinase activity PMID:16581800 IDA NCBITaxon:9606 UniProtKB:P27361-1 20080301 PRO:CNA PR:000026189 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (human) activated ERK1|activated MAPK3|hMAPK3/iso:1/Phos:1|UniProtKB:P27361-1, Thr-202, MOD:00047|Tyr-204, MOD:00048 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:7687743 IDA NCBITaxon:9606 UniProtKB:P27361-1 20080301 PRO:CNA PR:000026189 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (human) activated ERK1|activated MAPK3|hMAPK3/iso:1/Phos:1|UniProtKB:P27361-1, Thr-202, MOD:00047|Tyr-204, MOD:00048 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:7687743 IDA NCBITaxon:9606 UniProtKB:P27361-1 20080301 PRO:CNA PR:000026225 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse) mMCL1/iso:1/Clv:1|UniProtKB:P97287-1, 34-331 located_in GO:0005759 mitochondrial matrix MGI_ref:4822083|PMID:20627101 IDA NCBITaxon:10090 MGI:101769 20101220 MGI:MGI PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10823886|PMID:12943993 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 enables GO:0008134 transcription factor binding PMID:15084259 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 enables GO:0046332 SMAD binding PR:Q13485 PMID:15350224|PMID:9311995 IPI NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 located_in GO:0005634 nucleus PMID:10846168|PMID:15280432 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 part_of GO:0005667 transcription factor complex PMID:12374795 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 acts_upstream_of_or_within GO:0006366 transcription by RNA polymerase II PMID:10823886 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026333 smad3 isoform 1 phosphorylated 1 (human) hSMAD3/iso:1/Phos:1|UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8774881|PMID:9380693 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000026334 smad1 isoform 1 phosphorylated 1 (human) hSMAD1/iso:1/Phos:1|phospho-R-smad1 (human)|UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046 enables GO:0046332 SMAD binding PR:Q13485 PMID:9136927 IPI NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:000026334 smad1 isoform 1 phosphorylated 1 (human) hSMAD1/iso:1/Phos:1|phospho-R-smad1 (human)|UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046 located_in GO:0005634 nucleus PMID:11509558|PMID:9759503 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:000026334 smad1 isoform 1 phosphorylated 1 (human) hSMAD1/iso:1/Phos:1|phospho-R-smad1 (human)|UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:9759503 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:000026334 smad1 isoform 1 phosphorylated 1 (human) hSMAD1/iso:1/Phos:1|phospho-R-smad1 (human)|UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:000026335 TGF-beta 1 isoform 1 inactive form (human) hTGFB1/iso:1/inactive|PRO_0000033762, PRO_0000033763, Asn-82, MOD:00160|UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160 enables GO:0042803 protein homodimerization activity PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000026335 TGF-beta 1 isoform 1 inactive form (human) hTGFB1/iso:1/inactive|PRO_0000033762, PRO_0000033763, Asn-82, MOD:00160|UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160 located_in GO:0031012 extracellular matrix PMID:17015622|PMID:8294500 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000026335 TGF-beta 1 isoform 1 inactive form (human) hTGFB1/iso:1/inactive|PRO_0000033762, PRO_0000033763, Asn-82, MOD:00160|UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160 part_of GO:0032991 protein-containing complex PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000026335 TGF-beta 1 isoform 1 inactive form (human) hTGFB1/iso:1/inactive|PRO_0000033762, PRO_0000033763, Asn-82, MOD:00160|UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000026335 TGF-beta 1 isoform 1 inactive form (human) hTGFB1/iso:1/inactive|PRO_0000033762, PRO_0000033763, Asn-82, MOD:00160|UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160 NOT enables GO:0005160 transforming growth factor beta receptor binding PMID:2677679|PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human) hBMP2/iso:1/mature|PRO_0000033825|UniProtKB:P12643-1, 283-396 enables GO:0005102 signaling receptor binding PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human) hBMP2/iso:1/mature|PRO_0000033825|UniProtKB:P12643-1, 283-396 enables GO:0042803 protein homodimerization activity PMID:10074410 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human) hBMP2/iso:1/mature|PRO_0000033825|UniProtKB:P12643-1, 283-396 located_in GO:0005615 extracellular space PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human) hBMP2/iso:1/mature|PRO_0000033825|UniProtKB:P12643-1, 283-396 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human) hBMP2/iso:1/mature|PRO_0000033825|UniProtKB:P12643-1, 283-396 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:000026337 thrombospondin-4 isoform 1, signal peptide removed form (human) hTHBS4/iso:1/SigPep-|PRO_0000035852|UniProtKB:P35443-1, 27-961 enables GO:0005509 calcium ion binding PMID:7852353 IDA NCBITaxon:9606 UniProtKB:P35443-1 20080301 PRO:CNA PR:000026337 thrombospondin-4 isoform 1, signal peptide removed form (human) hTHBS4/iso:1/SigPep-|PRO_0000035852|UniProtKB:P35443-1, 27-961 enables GO:0008201 heparin binding PMID:7852353 IDA NCBITaxon:9606 UniProtKB:P35443-1 20080301 PRO:CNA PR:000026337 thrombospondin-4 isoform 1, signal peptide removed form (human) hTHBS4/iso:1/SigPep-|PRO_0000035852|UniProtKB:P35443-1, 27-961 located_in GO:0031012 extracellular matrix PMID:7490284 IDA NCBITaxon:9606 UniProtKB:P35443-1 20080301 PRO:CNA PR:000026337 thrombospondin-4 isoform 1, signal peptide removed form (human) hTHBS4/iso:1/SigPep-|PRO_0000035852|UniProtKB:P35443-1, 27-961 acts_upstream_of_or_within GO:0006930 substrate-dependent cell migration, cell extension PMID:7490284 IDA NCBITaxon:9606 UniProtKB:P35443-1 20080301 PRO:CNA PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human) hTHBS1/iso:1/SigPep-|PRO_0000035842|UniProtKB:P07996-1, 19-1170 enables GO:0004866 endopeptidase inhibitor activity PMID:8751720 TAS NCBITaxon:9606 UniProtKB:P07996-1 20080301 PRO:CNA PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human) hTHBS1/iso:1/SigPep-|PRO_0000035842|UniProtKB:P07996-1, 19-1170 located_in GO:0005615 extracellular space PMID:15662972 IDA NCBITaxon:9606 UniProtKB:P07996-1 20080301 PRO:CNA PR:000026340 Rho-associated protein kinase 1 isoform 1 cleaved 1 (human) hROCK1/iso:1/Clv:1|UniProtKB:Q13464-1, 1-1113 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:11283607 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:000026340 Rho-associated protein kinase 1 isoform 1 cleaved 1 (human) hROCK1/iso:1/Clv:1|UniProtKB:Q13464-1, 1-1113 increased enables GO:0004674 protein serine/threonine kinase activity PR:000002529 PMID:11283607 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 enables GO:0004672 protein kinase activity PMID:10706854 IDA NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 enables GO:0004707 MAP kinase activity PMID:10706854 IDA NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 enables GO:0005515 protein binding PMID:16291755 IPI NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:10958679 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 acts_upstream_of_or_within GO:0006935 chemotaxis PMID:10706854 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human) hMAPK1/iso:1/Phos:1|UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048 acts_upstream_of_or_within GO:0007165 signal transduction PMID:1540184 IDA NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:000026350 unique cartilage matrix-associated protein isoform 1 UCMA/iso:1 located_in GO:0031012 extracellular matrix MGI_ref:3772275|PMID:17707622 IDA NCBITaxon:10090 MGI:1915777 20110126 MGI:MGI PR:000026350 unique cartilage matrix-associated protein isoform 1 UCMA/iso:1 located_in GO:0005615 extracellular space MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20110126 MGI:MGI part_of(CL:0000138) PR:000026457 IkappaB kinase complex (human) IKK complex (human)|inhibitor of KappaB kinase (IKK) complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000026480 transcription factor PML isoform 1 phosphorylated 1 (human) hPML/iso:1/Phos:1|UniProtKB:P29590-1, Ser-403, MOD:00046|Thr-409, MOD:00047 located_in GO:0005634 nucleus PMID:20832753 EXP NCBITaxon:9606 UniProtKB:P29590-1 20110214 PRO:CNA Note=This phosphoform is not involved in cell proliferation (GO:0008283). PR:000026481 mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human) BMK1 active form|hMAPK7/iso:1/Phos:1|UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046|Tyr-221, MOD:00048 enables GO:0004707 MAP kinase activity PMID:20832753 EXP NCBITaxon:9606 UniProtKB:Q13164-1 20110214 PRO:CNA PR:000026481 mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human) BMK1 active form|hMAPK7/iso:1/Phos:1|UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046|Tyr-221, MOD:00048 enables GO:0005515 protein binding PR:P29590-1 PMID:20832753 IPI NCBITaxon:9606 UniProtKB:Q13164-1 20110214 PRO:CNA PR:000026481 mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human) BMK1 active form|hMAPK7/iso:1/Phos:1|UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046|Tyr-221, MOD:00048 located_in GO:0005634 nucleus PMID:20832753 EXP NCBITaxon:9606 UniProtKB:Q13164-1 20110214 PRO:CNA PR:000026481 mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human) BMK1 active form|hMAPK7/iso:1/Phos:1|UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046|Tyr-221, MOD:00048 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:20832753 EXP NCBITaxon:9606 UniProtKB:Q13164-1 20110214 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 enables GO:0005515 protein binding PR:Q04211 PMID:15542835 IPI NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 enables GO:0005515 protein binding PR:Q8BGV5 PMID:12370310 IPI NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 enables GO:0005515 protein binding PR:Q9QZH6 PMID:14633973 IPI NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 located_in GO:0005634 nucleus PMID:10504300|PMID:12151307|PMID:12370310 IDA NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 located_in GO:0005769 early endosome PMID:17592637 IDA NCBITaxon:10090 UniProtKB:P70340-1 20090305 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 part_of GO:0005667 transcription factor complex PMID:14633973 IDA NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15899870 IDA NCBITaxon:10090 UniProtKB:P70340-1 20130205 PRO:CNA PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse) mSMAD1/iso:1/Phos:1|UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:12370310|PMID:15198985 IDA NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:000026785 BH3-interacting domain death agonist isoform 1 cleaved 1 (mouse) mBID/iso:1/Clv:1|p15 (mouse)|PRO_0000223236|UniProtKB:P70444-1, 61-195 located_in GO:0031966 mitochondrial membrane MGI_ref:4940333|PMID:9873064 IDA NCBITaxon:10090 MGI:108093 20110314 MGI:MGI PR:000026785 BH3-interacting domain death agonist isoform 1 cleaved 1 (mouse) mBID/iso:1/Clv:1|p15 (mouse)|PRO_0000223236|UniProtKB:P70444-1, 61-195 acts_upstream_of_or_within GO:0001836 release of cytochrome c from mitochondria MGI_ref:4940333|PMID:9873064 IDA NCBITaxon:10090 MGI:108093 20110314 MGI:MGI PR:000026785 BH3-interacting domain death agonist isoform 1 cleaved 1 (mouse) mBID/iso:1/Clv:1|p15 (mouse)|PRO_0000223236|UniProtKB:P70444-1, 61-195 acts_upstream_of_or_within GO:0008637 apoptotic mitochondrial changes MGI_ref:1277505|PMID:9727492 IDA NCBITaxon:10090 MGI:108093 20110314 MGI:MGI PR:000026848 E3 ubiquitin-protein ligase COP1 phosphorylated 1 (human) hCOP1/Phos:1|phospho-COP1(Ser 387) (human)|UniProtKB:Q8NHY2-1, Ser-387, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:O70456 PMID:20843328 IPI NCBITaxon:9606 UniProtKB:Q8NHY2-1 20150504 PRO:CNA Note=Binding between proteins from heterogeneous species. Species information from cited reference PMID:10767298 PR:000027057 dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form (human) hMAP2K2/Phos:auto|human phospho-MEK2 enables GO:0004674 protein serine/threonine kinase activity PMID:8388392 EXP NCBITaxon:9606 UniProtKB:P36507-1 20110503 PRO:CNA PR:000027057 dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form (human) hMAP2K2/Phos:auto|human phospho-MEK2 located_in GO:0005829 cytosol Reactome:REACT_3571 EXP NCBITaxon:9606 UniProtKB:P36507-1 20110503 PRO:CNA PR:000027058 E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated 1 (human) hPELI2/Phos:1|UniProtKB:Q9HAT8, Thr-290, MOD:00047 located_in GO:0005829 cytosol Reactome:REACT_22715 EXP NCBITaxon:9606 UniProtKB:Q9HAT8-1 20110503 PRO:CNA PR:000027086 IRF7-P:IRF7-P complex (human) h(pIRF7)*2 enables GO:0003700 DNA-binding transcription factor activity PMID:11073981 EXP NCBITaxon:9606 20140718 PRO:CNA Note=Triggered by viral infection. PR:000027086 IRF7-P:IRF7-P complex (human) h(pIRF7)*2 located_in GO:0005654 nucleoplasm Reactome:REACT_21689 EXP NCBITaxon:9606 20140718 PRO:CNA PR:000027086 IRF7-P:IRF7-P complex (human) h(pIRF7)*2 acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140428 PRO:VS PR:000027086 IRF7-P:IRF7-P complex (human) h(pIRF7)*2 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000027086 IRF7-P:IRF7-P complex (human) h(pIRF7)*2 acts_upstream_of_or_within GO:0002753 cytoplasmic pattern recognition receptor signaling pathway Reactome:REACT_7146 EXP NCBITaxon:9606 20140428 PRO:VS PR:000027111 double-stranded RNA-activated factor 1 complex (human) human draf1 complex|human dsRNA-activated factor 1|human IRF3-P dimer:CBP/p300 enables GO:0043565 sequence-specific DNA binding PMID:10805757 EXP NCBITaxon:9606 Reactome:REACT_26303 20110513 PRO:CNA PR:000027111 double-stranded RNA-activated factor 1 complex (human) human draf1 complex|human dsRNA-activated factor 1|human IRF3-P dimer:CBP/p300 located_in GO:0005634 nucleus PMID:10805757 EXP NCBITaxon:9606 Reactome:REACT_26303 20110513 PRO:CNA PR:000027111 double-stranded RNA-activated factor 1 complex (human) human draf1 complex|human dsRNA-activated factor 1|human IRF3-P dimer:CBP/p300 acts_upstream_of_or_within GO:0034340 response to type I interferon PMID:10805757 EXP NCBITaxon:9606 Reactome:REACT_26303 20110513 PRO:CNA PR:000027132 G1/S-specific cyclin-D1 phosphorylated 1 (human) hCCND1/Phos:1|p-T286-CCND1 (human)|UniProtKB:P24385, Thr-286, MOD:00047 increased enables GO:0005515 protein binding PR:000037511 PR:000037513 PMID:17407548 IPI NCBITaxon:9606 20140903 PRO:KER PR:000027171 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mLY96/iso:1/SigPep-/NGlyco:1|PRO_0000018620, Asn-26/Asn-114/Asn-150, MOD:00160|UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160 located_in GO:0005615 extracellular space PMID:19783674 EXP NCBITaxon:10090 UniProtKB:Q9JHF9-1 20140814 PRO:CNA PR:000027171 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mLY96/iso:1/SigPep-/NGlyco:1|PRO_0000018620, Asn-26/Asn-114/Asn-150, MOD:00160|UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160 NOT enables GO:1990458 lipooligosaccharide binding PMID:19783674 EXP NCBITaxon:10090 UniProtKB:Q9JHF9-1 20140814 PRO:CNA Target=lipooligosaccharide (CHEBI:35371). PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse) MYD88s:Mal:activated TLR4 receptor (mouse)|TLR4MD2LPSditms acts_upstream_of_or_within GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665 EXP NCBITaxon:10090 20140428 TLR:AMM PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) IRAK4:MyD88:Mal:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) pIRAK4:MyD88:Mal:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000027196 TIRAP:PIP2:activated TLR4 (mouse) Mal:activated TLR4 complex (mouse)|TIRAP:PIP2:MD2:LPS:TLR4 complex (mouse)|TLR4MD2LPSditirap' acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:12447442 EXP NCBITaxon:10090 20140718 TLR:AMM PR:000027204 ticam2:activated TLR4 complex (mouse) TLR4MD2LPSditram'|TRAM:activated TLR4 (mouse) located_in GO:0010008 endosome membrane PMID:18222170 EXP NCBITaxon:10090 20130129 PRO:CNA PR:000027204 ticam2:activated TLR4 complex (mouse) TLR4MD2LPSditram'|TRAM:activated TLR4 (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170 EXP NCBITaxon:10090 20130129 PRO:CNA PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) TLR4MD2LPSditt|TRIF:TRAM:activated TLR4 (mouse) located_in GO:0010008 endosome membrane PMID:18222170 EXP NCBITaxon:10090 20130129 PRO:CNA PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) TLR4MD2LPSditt|TRIF:TRAM:activated TLR4 (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170 EXP NCBITaxon:10090 20130129 PRO:CNA PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) TLR4MD2LPSditt|TRIF:TRAM:activated TLR4 (mouse) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:18222170 EXP NCBITaxon:10090 20140514 PRO:CNA PR:000027208 ticam1:ticam2:activated TLR4 complex (human) TRIF:TRAM:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_7861 EXP NCBITaxon:9606 20130129 PRO:CNA PR:000027208 ticam1:ticam2:activated TLR4 complex (human) TRIF:TRAM:activated TLR4 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130129 PRO:CNA PR:000027208 ticam1:ticam2:activated TLR4 complex (human) TRIF:TRAM:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140514 PRO:CNA PR:000027223 CALCA gene translation product (mouse) mCALCA located_in GO:0005737 cytoplasm MGI_ref:3028786|PMID:14765981 IDA NCBITaxon:10090 MGI:2151253 20110621 MGI:MGI part_of(MA:0000792),part_of(CL:0000150)|part_of(MA:0000792),part_of(CL:0000167) PR:000027273 Toll-like receptor 1-Toll-like receptor 2 protein complex (human) TLR1-TLR2 protein complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000027461 apoptosis regulator Bcl-2 isoform 1 phosphorylated 2 (human) hBCL2/iso:1/Phos:2|UniProtKB:P10415-1, Thr-74, MOD:00047 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:12039864 EXP NCBITaxon:9606 UniProtKB:P10415-1 20110701 PRO:PD Note=In context of glucocorticoid induced apoptosis PR:000027463 apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human) hBCL2/iso:1/Phos:3|UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046 acts_upstream_of_or_within GO:0016239 positive regulation of macroautophagy PMID:18570871|PMID:19029119 EXP NCBITaxon:9606 UniProtKB:P10415-1 20110701 PRO:PD Kinase=JNK1 [PR:P45983]. Disrupts Bcl-2 (unmodified)/Beclin 1 complex. Induced in response to ceramide (19029119). PR:000027463 apoptosis regulator Bcl-2 isoform 1 phosphorylated 3 (human) hBCL2/iso:1/Phos:3|UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-70/Ser-87, MOD:00046 NOT enables GO:0005515 protein binding PR:Q14457 PMID:18570871|PMID:19029119 IPI NCBITaxon:9606 UniProtKB:P10415-1 20110701 PRO:PD Kinase=JNK1 [PR:P45983]. Disrupts Bcl-2 (unmodified)/Beclin 1 complex. Induced in response to ceramide (19029119). PR:000027465 apoptosis regulator Bcl-2 isoform 1 phosphorylated 4 (human) hBCL2/iso:1/Phos:4|UniProtKB:P10415-1, Thr-69, MOD:00047|Ser-87, MOD:00046 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process PMID:15703383 EXP NCBITaxon:9606 UniProtKB:P10415-1 20110701 PRO:PD Kinase=JNK [PR:P45983]. Inducing agent: Cephalostatin 1 PR:000027467 apoptosis regulator Bcl-2 isoform 1 phosphorylated 5 (human) hBCL2/iso:1/Phos:5|UniProtKB:P10415-1, Thr-56, MOD:00047 acts_upstream_of_or_within GO:0045839 negative regulation of mitotic nuclear division PMID:10766756 EXP NCBITaxon:9606 UniProtKB:P10415-1 20110701 PRO:PD Kinase=CDC2 [PR:P06493]. Induced by okadaic acid. PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human) hBECN1/iso:1/Phos:1|UniProtKB:Q14457-1, Thr-119, MOD:00047 acts_upstream_of_or_within GO:0010508 positive regulation of autophagy PMID:19180116|PMID:19395874 EXP NCBITaxon:9606 UniProtKB:Q14457-1 20110701 PRO:PD Kinase=DAPK (DAPK family: DAPK1/2/3 [PR:000006276, PR:000006277, PR:000006278] PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human) hBECN1/iso:1/Phos:1|UniProtKB:Q14457-1, Thr-119, MOD:00047 decreased enables GO:0005515 protein binding PR:000027487 PR:P10415 PMID:19395874 IPI NCBITaxon:9606 UniProtKB:Q14457-1 20110701 PRO:PD PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human) hBECN1/iso:1/Phos:1|UniProtKB:Q14457-1, Thr-119, MOD:00047 decreased enables GO:0005515 protein binding PR:000027487 PR:Q07817-1 PMID:19180116 IPI NCBITaxon:9606 UniProtKB:Q14457-1 20110701 PRO:PD PR:000027473 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 (human) hAKT1/iso:1/Phos:2|UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:16549426 EXP NCBITaxon:9606 UniProtKB:P31749-1 20110701 PRO:PD Note=Autophosphorylation sites are situated in characteristic Akt substrate motif (RXRXX(S/T) PR:000027479 epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human) hEGFR/iso:1/SigPep-/Phos:1|PRO_0000016665, Tyr-869, MOD:00048|UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048 located_in GO:0005634 nucleus PMID:18789131 EXP NCBITaxon:9606 UniProtKB:P00533-1 20110701 PRO:PD Kinase=Src [PR:P12931; PR:000027234]. Authors did not consider the signal peptide of EGFR (residue 1-24) hence paper refers to Y845 (instead of Y869). Inducing agent: Ionizing radiation.Activates DNA-PK by inducing phosphorylation at T2609 PR:000027479 epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human) hEGFR/iso:1/SigPep-/Phos:1|PRO_0000016665, Tyr-869, MOD:00048|UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048 acts_upstream_of_or_within GO:0034504 protein localization to nucleus PMID:18789131 EXP NCBITaxon:9606 UniProtKB:P00533-1 20110701 PRO:PD Kinase=Src [PR:P12931; PR:000027234]. Authors did not consider the signal peptide of EGFR (residue 1-24) hence paper refers to Y845 (instead of Y869). Inducing agent: Ionizing radiation.Activates DNA-PK by inducing phosphorylation at T2609 PR:000027492 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human) hIRAK1/iso:1/Phos:3|pp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047 enables GO:0004674 protein serine/threonine kinase activity PMID:14625308 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027492 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human) hIRAK1/iso:1/Phos:3|pp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047 acts_upstream_of_or_within GO:0070498 interleukin-1-mediated signaling pathway PMID:14625308 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027493 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human) hIRAK1/iso:1/Phos:4|hp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 enables GO:0004674 protein serine/threonine kinase activity PMID:14625308 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027493 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human) hIRAK1/iso:1/Phos:4|hp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 enables GO:0005515 protein binding PR:Q9Y4K3 PMID:14625308 IPI NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027493 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human) hIRAK1/iso:1/Phos:4|hp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 acts_upstream_of_or_within GO:0070498 interleukin-1-mediated signaling pathway PMID:14625308 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027493 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human) hIRAK1/iso:1/Phos:4|hp-IRAK1 (human)|UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 NOT enables GO:0005515 protein binding PR:Q99836 PMID:14625308 IPI NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA Note=Dissociation from ILR complex. Phosphorylated in PTS domain. PR:000027494 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human) hIRAK1/iso:1/Phos:1|UniProtKB:P51617-1, Thr-209, MOD:00047 enables GO:0005515 protein binding PR:Q9NWZ3 PMID:11960013 IPI NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027494 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human) hIRAK1/iso:1/Phos:1|UniProtKB:P51617-1, Thr-209, MOD:00047 enables GO:0016301 kinase activity PMID:11960013 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) pIRAK1:IRAK4:MyD88:Mal:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000027692 nuclear receptor coactivator 3 isoform 1 phosphorylated 1 (human) hNCOA3/iso:1/Phos:1|UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046 enables GO:0005515 protein binding PR:O43791 PMID:21577200 IPI NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD PR:000027694 nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human) hNCOA3/iso:1/Phos:2|UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046 enables GO:0003713 transcription coactivator activity PMID:19339517 EXP NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD PR:000027694 nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human) hNCOA3/iso:1/Phos:2|UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046 acts_upstream_of_or_within GO:0030374 nuclear receptor coactivator activity PMID:19339517 EXP NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD PR:000027696 nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human) hNCOA3/iso:1/Phos:3|UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048 enables GO:0030331 nuclear estrogen receptor binding PR:000007204 PMID:18765637 IPI NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD Kinase=c-Abl tyrosine kinase [PR:P00519]. Induced by insulin-like growth factor 1, epidermal growth factor, or estrogen treatment in breast cancer cells PR:000027696 nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human) hNCOA3/iso:1/Phos:3|UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048 enables GO:0035035 histone acetyltransferase binding PR:000027108 PMID:18765637 IPI NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD Kinase=c-Abl tyrosine kinase [PR:P00519]. Induced by insulin-like growth factor 1, epidermal growth factor, or estrogen treatment in breast cancer cells PR:000027696 nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human) hNCOA3/iso:1/Phos:3|UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048 acts_upstream_of_or_within GO:0030374 nuclear receptor coactivator activity PMID:18765637 EXP NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20110720 PRO:PD Kinase=c-Abl tyrosine kinase [PR:P00519]. Induced by insulin-like growth factor 1, epidermal growth factor, or estrogen treatment in breast cancer cells PR:000027724 estrogen receptor isoform 1 phosphorylated 1 (human) hESR1/iso:1/Phos:1|phospho-ERalpha-Ser-167|UniProtKB:P03372-1, Ser-167, MOD:00046 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:19940156 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110901 PRO:PD Kinase=IKKepsilon [PR:Q14164; PR:000001778] PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human) hESR1/iso:1/Phos:2|UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048 enables GO:0042803 protein homodimerization activity PMID:20101225 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110901 PRO:CNA Kinase=c-Abl tyrosine kinase [PR:P00519; PR:000003582]. interaction mediated by two PXXP motifs of ERalpha and the c-Abl SH3 domain PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human) hESR1/iso:1/Phos:2|UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048 located_in GO:0005634 nucleus PMID:20101225 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110901 PRO:CNA Kinase=c-Abl tyrosine kinase [PR:P00519; PR:000003582]. interaction mediated by two PXXP motifs of ERalpha and the c-Abl SH3 domain PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human) hESR1/iso:1/Phos:2|UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048 acts_upstream_of_or_within GO:0010628 positive regulation of gene expression PMID:20101225 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110901 PRO:PD Kinase=c-Abl tyrosine kinase [PR:P00519; PR:000003582]. interaction mediated by two PXXP motifs of ERalpha and the c-Abl SH3 domain PR:000027756 estrogen receptor isoform 1 acetylated 1 (human) AcK266/268-ERalpha (human)|ERalpha acetylated (human)|hESR1/iso:1/Ac:1|UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064 enables GO:0003677 DNA binding PMID:16497729 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110909 PRO:PD Acetylase=EP300 [PR:Q09472; PR:000007102] PR:000027766 cellular tumor antigen p53 isoform 1 dimethylated 1 (human) hTP53/iso:1/Me2:1|p53K382me2|UniProtKB:P04637-1, Lys-382, MOD:00084 enables GO:0005515 protein binding PR:Q12888 PMID:18840612 IPI NCBITaxon:9606 UniProtKB:P04637-1 20110919 PRO:PD PR:000027774 cellular tumor antigen p53 isoform 1 acetylated 1 (human) hTP53/iso:1/Ac:1|p53-acLys120|UniProtKB:P04637-1, Lys-120, MOD:00064 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process PMID:17189187 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110920 PRO:PD Acetylase=hMOF. PR:000027776 estrogen receptor isoform 1 phosphorylated 4 (human) hESR1/iso:1/Phos:4|pERalpha-Thr311|UniProtKB:P03372-1, Thr-311, MOD:00047 located_in GO:0005634 nucleus PMID:12138194 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110920 PRO:PD Kinase=p38 MAPK [PR:Q16539; PR:000003107]. PR:000027776 estrogen receptor isoform 1 phosphorylated 4 (human) hESR1/iso:1/Phos:4|pERalpha-Thr311|UniProtKB:P03372-1, Thr-311, MOD:00047 acts_upstream_of_or_within GO:0010628 positive regulation of gene expression PMID:12138194 EXP NCBITaxon:9606 UniProtKB:P03372-1 20110920 PRO:PD Kinase=p38 MAPK [PR:Q16539; PR:000003107]. PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human) hTP53/iso:1/Me:3|p53-mLys372|UniProtKB:P04637-1, Lys-372, MOD:00663 located_in GO:0005634 nucleus PMID:15525938 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human) hTP53/iso:1/Me:3|p53-mLys372|UniProtKB:P04637-1, Lys-372, MOD:00663 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:15525938 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD PR:000027810 cellular tumor antigen p53 isoform 1 methylated 4 (human) hTP53/iso:1/Me:4|p53-mLys370|UniProtKB:P04637-1, Lys-370, MOD:00663 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:17108971 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD Lysine methyltransferase, SMYD2 [PR:Q9NRG4]. PR:000027812 cellular tumor antigen p53 isoform 1 acetylated 2 (human) hTP53/iso:1/Ac:2|p53-acLys382|UniProtKB:P04637-1, Lys-382, MOD:00064 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:20228809 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD Acetylace=Acetyltransferase EP300 [PR:Q09472; PR:000007102]. PR:000027814 cellular tumor antigen p53 isoform 1 phosphorylated 12 (human) hTP53/iso:1/Phos:12|p53-pSer15-pSer392|UniProtKB:P04637-1, Ser-15/Ser-392, MOD:00046 located_in GO:0005634 nucleus PMID:21317932 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD Kinase=NUAK1 [PR:O60285; PR:000011473]. NUAK1 gets activated upon phosphorylation by LKB1. PR:000027814 cellular tumor antigen p53 isoform 1 phosphorylated 12 (human) hTP53/iso:1/Phos:12|p53-pSer15-pSer392|UniProtKB:P04637-1, Ser-15/Ser-392, MOD:00046 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:21317932 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD Kinase=NUAK1 [PR:O60285; PR:000011473]. NUAK1 gets activated upon phosphorylation by LKB1. PR:000027818 zinc finger protein ZFPM1 isoform 2 (mouse) FOG1S (mouse)|mZFPM1/iso:2|UniProtKB:O35615-1, 19-995 located_in GO:0005634 nucleus MGI_ref:4422158|PMID:19654328 IDA NCBITaxon:10090 MGI:1095400 20110810 MGI:MGI PR:000027818 zinc finger protein ZFPM1 isoform 2 (mouse) FOG1S (mouse)|mZFPM1/iso:2|UniProtKB:O35615-1, 19-995 located_in GO:0005737 cytoplasm MGI_ref:4422158|PMID:19654328 IDA NCBITaxon:10090 MGI:1095400 20110810 MGI:MGI PR:000027833 cellular tumor antigen p53 isoform 1 phosphorylated 9 (human) hTP53/iso:1/Phos:9|p53-pSer15-pSer37|UniProtKB:P04637-1, Ser-15/Ser-37, MOD:00046 acts_upstream_of_or_within GO:0010468 regulation of gene expression PMID:14712210 EXP NCBITaxon:9606 UniProtKB:P04637-1 20110929 PRO:PD PR:000027839 cellular tumor antigen p53 isoform 1 phosphorylated 11 (human) hTP53/iso:1/Phos:11|p53-pSer183-pSer269-pThr284|UniProtKB:P04637-1, Ser-183/Ser-269, MOD:00046|Thr-284, MOD:00047 acts_upstream_of_or_within GO:0010629 negative regulation of gene expression PMID:20959462 EXP NCBITaxon:9606 UniProtKB:P04637-1 20111029 PRO:PD Kinase=AURKB [PR:Q96GD4] PR:000027844 p53 complex sumoylated 1 (human) Sup53 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:19339993 EXP NCBITaxon:9606 20110929 PRO:PD Evidence=Fig3. Evidence=7. PR:000027844 p53 complex sumoylated 1 (human) Sup53 NOT enables GO:0003677 DNA binding PMID:19339993 EXP NCBITaxon:9606 20110929 PRO:PD Evidence=Fig3. PR:000027885 nuclear receptor coactivator 3 isoform 1 acetylated 1 (human) hNCOA3/iso:1/Ac:1|NCOA3-acLys619-acLys620|UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064 NOT enables GO:0016922 nuclear receptor binding PMID:10490106 EXP NCBITaxon:9606 UniProtKB:Q9Y6Q9-1 20111127 PRO:PD PR:000027889 signal transducer and activator of transcription 1 isoform 1 phosphorylated 3 (human) hSTAT1/iso:1/Phos:3|STAT1-pSer727|UniProtKB:P42224-1, Ser-727, MOD:00046 located_in GO:0005634 nucleus PMID:15322115 EXP NCBITaxon:9606 UniProtKB:P42224-1 20111127 PRO:PD PR:000027889 signal transducer and activator of transcription 1 isoform 1 phosphorylated 3 (human) hSTAT1/iso:1/Phos:3|STAT1-pSer727|UniProtKB:P42224-1, Ser-727, MOD:00046 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process PMID:15322115 EXP NCBITaxon:9606 UniProtKB:P42224-1 20111127 PRO:PD PR:000027894 forkhead box protein O1 isoform 1 phosphorylated 1 (human) FOXO1-pSer249|hFOXO1/iso:1/Phos:1|UniProtKB:Q12778-1, Ser-249, MOD:00046 located_in GO:0005634 nucleus PMID:18356527 EXP NCBITaxon:9606 UniProtKB:Q12778-1 20111127 PRO:PD PR:000027894 forkhead box protein O1 isoform 1 phosphorylated 1 (human) FOXO1-pSer249|hFOXO1/iso:1/Phos:1|UniProtKB:Q12778-1, Ser-249, MOD:00046 acts_upstream_of_or_within GO:0010628 positive regulation of gene expression PMID:18356527 EXP NCBITaxon:9606 UniProtKB:Q12778-1 20111127 PRO:PD PR:000027894 forkhead box protein O1 isoform 1 phosphorylated 1 (human) FOXO1-pSer249|hFOXO1/iso:1/Phos:1|UniProtKB:Q12778-1, Ser-249, MOD:00046 NOT enables GO:0071889 14-3-3 protein binding PMID:18356527 EXP NCBITaxon:9606 UniProtKB:Q12778-1 20111127 PRO:PD PR:000027930 myocyte-specific enhancer factor 2C isoform 2 acetylated 1 (mouse) MEF2C-AcLys4|mMEF2C/iso:2/Ac:1|UniProtKB:Q8CFN5-2, Lys-4, MOD:00064 acts_upstream_of_or_within GO:0035914 skeletal muscle cell differentiation PMID:18086704 EXP NCBITaxon:10090 UniProtKB:Q8CFN5-2 20111129 PRO:CNA PR:000027930 myocyte-specific enhancer factor 2C isoform 2 acetylated 1 (mouse) MEF2C-AcLys4|mMEF2C/iso:2/Ac:1|UniProtKB:Q8CFN5-2, Lys-4, MOD:00064 increased enables GO:0003677 DNA binding PR:000027940 PMID:18086704 EXP NCBITaxon:10090 UniProtKB:Q8CFN5-2 20111129 PRO:CNA Evidence=Fig4 PR:000027938 acetylated STAT3 homodimer (human) h(STAT3/AcRes+)*2 located_in GO:0005634 nucleus PMID:19506034 EXP NCBITaxon:9606 20111129 PRO:CNA PR:000027943 CDK9:cyclin-T1 (human) CDK9-cyclin T1 (human)|CDK9-cyclinT1 (human)|dimeric P-TEFb human enables GO:0097472 cyclin-dependent protein kinase activity PMID:17452463 EXP NCBITaxon:9606 20111129 PRO:CNA Evidence=Fig5 PR:000027943 CDK9:cyclin-T1 (human) CDK9-cyclin T1 (human)|CDK9-cyclinT1 (human)|dimeric P-TEFb human located_in GO:0005634 nucleus PMID:17452463 EXP NCBITaxon:9606 20111129 PRO:CNA Evidence=HeLa nuclear extracts. PR:000027943 CDK9:cyclin-T1 (human) CDK9-cyclin T1 (human)|CDK9-cyclinT1 (human)|dimeric P-TEFb human acts_upstream_of_or_within GO:0006354 DNA-templated transcription elongation PMID:17452463 EXP NCBITaxon:9606 20111129 PRO:CNA Evidence=Fig7 PR:000027943 CDK9:cyclin-T1 (human) CDK9-cyclin T1 (human)|CDK9-cyclinT1 (human)|dimeric P-TEFb human acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:17452463 EXP NCBITaxon:9606 20111129 PRO:CNA PR:000028337 serine/threonine-protein kinase CDG1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-CDG1/iso:1/Phos:1|pCDG1 (Arabidopsis thaliana)|UniProtKB:Q9LSE1-1, Ser-44/Ser-47/Ser-234, MOD:00046 enables GO:0004672 protein kinase activity PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q9LSE1-1 20130205 PRO:LVM Target=PR:Q9LR78-1. PR:000028337 serine/threonine-protein kinase CDG1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-CDG1/iso:1/Phos:1|pCDG1 (Arabidopsis thaliana)|UniProtKB:Q9LSE1-1, Ser-44/Ser-47/Ser-234, MOD:00046 enables GO:0005515 protein binding PR:Q9LR78-1 PMID:21855796 IPI NCBITaxon:3702 UniProtKB:Q9LSE1-1 20130205 PRO:LVM PR:000028337 serine/threonine-protein kinase CDG1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-CDG1/iso:1/Phos:1|pCDG1 (Arabidopsis thaliana)|UniProtKB:Q9LSE1-1, Ser-44/Ser-47/Ser-234, MOD:00046 located_in GO:0005886 plasma membrane PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q9LSE1-1 20130205 PRO:LVM PR:000028337 serine/threonine-protein kinase CDG1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-CDG1/iso:1/Phos:1|pCDG1 (Arabidopsis thaliana)|UniProtKB:Q9LSE1-1, Ser-44/Ser-47/Ser-234, MOD:00046 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q9LSE1-1 20130205 PRO:LVM PR:000028342 serine/threonine-protein phosphatase BSU1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BSU1/iso:1/Phos:1|pBSU1 (Arabidopsis thaliana)|UniProtKB:Q9LR78-1, Ser-395/Ser-444/Ser-764, MOD:00046 enables GO:0004721 phosphoprotein phosphatase activity PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q9LR78-1 20130205 PRO:LVM Target=PR:000035742. PR:000028342 serine/threonine-protein phosphatase BSU1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BSU1/iso:1/Phos:1|pBSU1 (Arabidopsis thaliana)|UniProtKB:Q9LR78-1, Ser-395/Ser-444/Ser-764, MOD:00046 enables GO:0005515 protein binding PR:000035742 PMID:21855796 IPI NCBITaxon:3702 UniProtKB:Q9LR78-1 20130205 PRO:LVM PR:000028342 serine/threonine-protein phosphatase BSU1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BSU1/iso:1/Phos:1|pBSU1 (Arabidopsis thaliana)|UniProtKB:Q9LR78-1, Ser-395/Ser-444/Ser-764, MOD:00046 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q9LR78-1 20130205 PRO:LVM PR:000028347 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/iso:1/Phos:1|UniProtKB:Q94F62-1, Tyr-610, MOD:00048|MOD:00046|MOD:00047 enables GO:0004712 protein serine/threonine/tyrosine kinase activity PMID:20876109|PMID:21350342 EXP NCBITaxon:3702 UniProtKB:Q94F62-1 20111219 PRO:CNA Target=PR:Q94F62-1. PR:000028347 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/iso:1/Phos:1|UniProtKB:Q94F62-1, Tyr-610, MOD:00048|MOD:00046|MOD:00047 acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:20876109 EXP NCBITaxon:3702 UniProtKB:Q94F62-1 20111219 PRO:CNA PR:000028347 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/iso:1/Phos:1|UniProtKB:Q94F62-1, Tyr-610, MOD:00048|MOD:00046|MOD:00047 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:21350342 EXP NCBITaxon:3702 UniProtKB:Q94F62-1 20130206 PRO:LVM PR:000028352 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 1 (Arabidopsis thaliana) At-BZR1/Phos:1|AtBZR1 phosphorylated|pAtBZR1|phospho-AtBZR1|UniProtKB:Q8S307, Ser-173, MOD:00046|Thr-177, MOD:00047|(Ser-130, MOD:00046 and/or Ser-134, MOD:00046 and/or Ser-118, MOD:00046 and/or Ser-114, MOD:00046 and/or Ser-110, MOD:00046 and/or Ser-122, MOD:00046 and/or Ser-126, MOD:00046 and/or Ser-138, MOD:00046) enables GO:0071889 14-3-3 protein binding PMID:17873094 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130205 PRO:LVM PR:000028352 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 1 (Arabidopsis thaliana) At-BZR1/Phos:1|AtBZR1 phosphorylated|pAtBZR1|phospho-AtBZR1|UniProtKB:Q8S307, Ser-173, MOD:00046|Thr-177, MOD:00047|(Ser-130, MOD:00046 and/or Ser-134, MOD:00046 and/or Ser-118, MOD:00046 and/or Ser-114, MOD:00046 and/or Ser-110, MOD:00046 and/or Ser-122, MOD:00046 and/or Ser-126, MOD:00046 and/or Ser-138, MOD:00046) located_in GO:0005737 cytoplasm PMID:17873094 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130205 PRO:LVM PR:000028357 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:1|pAtBRI1|phospho-AtBRI1|UniProtKB:O22476-1, Tyr-831/Tyr-956/Tyr-1052/Tyr-1057/Tyr-1072, MOD:00048 acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:19124768 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130412 PRO:LVM PR:000028410 thrombospondin-1, signal peptide removed form (human) hTHBS1/SigPep-|PRO_0000035842|UniProtKB:P07996-1, 19-1170 located_in GO:0005615 extracellular space PMID:15662972 IDA NCBITaxon:9606 20080301 PRO:CNA PR:000028458 SCF(TIR1) complex (Arabidopsis thaliana) acts_upstream_of_or_within GO:0009734 auxin-activated signaling pathway PMID:21370976 TAS NCBITaxon:3702 20111219 PRO:CNA PR:000028460 auxin-IAA7-SCF(TIR1) complex (Arabidopsis thaliana) acts_upstream_of_or_within GO:0009734 auxin-activated signaling pathway PMID:21370976 TAS NCBITaxon:3702 20111219 PRO:CNA PR:000028465 SCF(COI1) complex (Arabidopsis thaliana) acts_upstream_of_or_within GO:0009867 jasmonic acid mediated signaling pathway PMID:21370976 TAS NCBITaxon:3702 20111219 PRO:CNA PR:000028483 serine/threonine-protein kinase BIK1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BIK1/iso:1/Phos:1|UniProtKB:O48814-1, Thr-237, MOD:00047 acts_upstream_of_or_within GO:0042742 defense response to bacterium PMID:20018686 EXP NCBITaxon:3702 UniProtKB:O48814-1 20111219 PRO:CNA PR:000028483 serine/threonine-protein kinase BIK1 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-BIK1/iso:1/Phos:1|UniProtKB:O48814-1, Thr-237, MOD:00047 acts_upstream_of_or_within GO:0002221 pattern recognition receptor signaling pathway PMID:20018686 EXP NCBITaxon:3702 UniProtKB:O48814-1 20111219 PRO:CNA PR:000028503 FLS2:BAK1 complex (Arabidopsis thaliana) Flg22:AtFls2:AtBak1 complex enables GO:0004672 protein kinase activity PMID:20018686 EXP NCBITaxon:3702 20111219 PRO:CNA Target=PR:000028483. PR:000028503 FLS2:BAK1 complex (Arabidopsis thaliana) Flg22:AtFls2:AtBak1 complex enables GO:0004672 protein kinase activity PMID:27884939 EXP NCBITaxon:3702 20161128 PRO:CNA Target=PR:000049767. PR:000028503 FLS2:BAK1 complex (Arabidopsis thaliana) Flg22:AtFls2:AtBak1 complex acts_upstream_of_or_within GO:0042742 defense response to bacterium PMID:17625569 EXP NCBITaxon:3702 20111219 PRO:CNA PR:000028503 FLS2:BAK1 complex (Arabidopsis thaliana) Flg22:AtFls2:AtBak1 complex acts_upstream_of_or_within GO:0002221 pattern recognition receptor signaling pathway PMID:17625569|PMID:20103591 EXP NCBITaxon:3702 20111219 PRO:CNA PR:000028505 BRI1:BAK1 complex (Arabidopsis thaliana) AtBRI1/BAK1 complex enables GO:0004712 protein serine/threonine/tyrosine kinase activity PMID:18694562 EXP NCBITaxon:3702 20111219 PRO:CNA PR:000028505 BRI1:BAK1 complex (Arabidopsis thaliana) AtBRI1/BAK1 complex acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:18694562 EXP NCBITaxon:3702 20111219 PRO:CNA PR:000028510 zona pellucida receptor complex 1 (mouse) sperm protein complex acts_upstream_of_or_within GO:0007339 binding of sperm to zona pellucida PMID:21880732 EXP NCBITaxon:10090 20121113 PRO:KC Note=Purified zona pellucida receptor binding complex shown to bind to solubilized zona pellucida proteins PR:000028569 C-terminal-binding protein 2 isoform 1 acetylated 1 (human) CtBP2 acetylated (human)|hCTBP2/iso:1/Ac:1|UniProtKB:P56545-1, Lys-6/Lys-8/Lys-10, MOD:00064 located_in GO:0005634 nucleus PMID:16356938 EXP NCBITaxon:9606 UniProtKB:P56545-1 20120214 PRO:CNA PR:000028573 ETS translocation variant 1 isoform 1 acetylated 1 (human) hETV1/iso:1/Ac:1|UniProtKB:P50549-1, Lys-33/Lys-116, MOD:00064 increased enables GO:0003677 DNA binding PR:000028622 PMID:12917345 EXP NCBITaxon:9606 UniProtKB:P50549-1 20120214 PRO:CNA PR:000028592 endonuclease 8-like 2 isoform 1, initiator methionine removed acetylated 1 (human) hNEIL2/iso:1/InitMet-/Ac:1|NEIL2 acetylated (human)|UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, MOD:00064 decreased enables GO:0019104 DNA N-glycosylase activity PR:000045372 PMID:15175427 EXP NCBITaxon:9606 UniProtKB:Q969S2-1 20120214 PRO:CNA PR:000028600 N-glycosylase/DNA lyase isoform 1 acetylated 1 (human) hOGG1/iso:1/Ac:1|human 8-oxoguanine-DNA glycosylase acetylated|human AcOGG1|human OGG1 acetylated|UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064 located_in GO:0005634 nucleus PMID:16478987 EXP NCBITaxon:9606 UniProtKB:O15527-1 20120214 PRO:CNA Evidence=Fig4. PR:000028604 DNA polymerase beta acetylated 1 (human) hPOLB/Ac:1|UniProtKB:P06746, Lys-72, MOD:00064 decreased enables GO:0016829 lyase activity PR:000045373 PMID:12453427 EXP NCBITaxon:9606 UniProtKB:P06746-1 20120214 PRO:CNA PR:000028616 transcription factor Jun isoform 1 acetylated 1 (human) hJUN/iso:1/Ac:1|UniProtKB:P05412-1, Lys-268/Lys-271/Lys-273, MOD:00064 located_in GO:0005737 cytoplasm PMID:18793328 EXP NCBITaxon:9606 UniProtKB:P05412-1 20120214 PRO:CNA PR:000028616 transcription factor Jun isoform 1 acetylated 1 (human) hJUN/iso:1/Ac:1|UniProtKB:P05412-1, Lys-268/Lys-271/Lys-273, MOD:00064 acts_upstream_of_or_within GO:0042692 muscle cell differentiation PMID:18793328 EXP NCBITaxon:9606 UniProtKB:P05412-1 20120214 PRO:CNA PR:000028678 ticam2:activated TLR4 complex (human) TRAM:activated TLR4 (human)|TRAM:TLR4:MD2:LPS:CD14 (human) located_in GO:0010008 endosome membrane Reactome:REACT_7083 EXP NCBITaxon:9606 20130129 PRO:CNA PR:000028678 ticam2:activated TLR4 complex (human) TRAM:activated TLR4 (human)|TRAM:TLR4:MD2:LPS:CD14 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130129 PRO:CNA PR:000028678 ticam2:activated TLR4 complex (human) TRAM:activated TLR4 (human)|TRAM:TLR4:MD2:LPS:CD14 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140514 PRO:CNA PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRAM:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR4 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_25948 EXP NCBITaxon:9606 20130412 PRO:CNA PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRAM:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR4 complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130412 PRO:CNA PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRAM:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR4 complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140514 PRO:CNA PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse) TRAF3:TRIF:TRAM:activated TLR4 (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:16306937 EXP NCBITaxon:10090 20130129 PRO:CNA PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse) TRAF3:TRIF:TRAM:activated TLR4 (mouse) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:16306937 EXP NCBITaxon:10090 20140514 PRO:CNA PR:000028709 microtubule-associated protein tau sequence variant R5H (human) hMAPT/var:R5H|UniProtKB:P10636-8, Arg-5, CHEBI:29979 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:11921059|UniProtKB_VAR:VAR_019660 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019660 20120412 PRO:DAN PR:000028710 microtubule-associated protein tau sequence variant R5L (human) hMAPT/var:R5L|UniProtKB:P10636-8, Arg-5, CHEBI:29967 associated_with_disease_progression DOID:678 progressive supranuclear palsy PMID:12325083|UniProtKB_VAR:VAR_019661 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019661 20120412 PRO:DAN PR:000028710 microtubule-associated protein tau sequence variant R5L (human) hMAPT/var:R5L|UniProtKB:P10636-8, Arg-5, CHEBI:29967 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-r5l EXP NCBITaxon:9606 Alzforum:mapt-r5l 20180510 PRO:DAN PR:000028724 microtubule-associated protein tau sequence variant N296del (human) hMAPT/var:N296del|UniProtKB:P10636-1, 1-612, 614-758|UniProtKB:P10636-8, 1-295, 297-441 associated_with_disease_progression DOID:678 progressive supranuclear palsy PMID:11220749|PMID:11906000|PMID:14991828|PMID:14991829|UniProtKB_VAR:VAR_019664 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019664 20120412 PRO:DAN PR:000028724 microtubule-associated protein tau sequence variant N296del (human) hMAPT/var:N296del|UniProtKB:P10636-1, 1-612, 614-758|UniProtKB:P10636-8, 1-295, 297-441 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-n296del-dn296 EXP NCBITaxon:9606 Alzforum:mapt-n296del-dn296 20180510 PRO:DAN PR:000028845 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 myristoylated 1 (mouse) mSH3TC2/iso:1/Myr:1|UniProtKB:Q80VA5-1, 2-1289, Gly-2, MOD:00068 located_in GO:0005886 plasma membrane MGI_ref:4366127|PMID:19805030 IDA NCBITaxon:10090 MGI:2444417 20120507 MGI:MGI PR:000028845 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 myristoylated 1 (mouse) mSH3TC2/iso:1/Myr:1|UniProtKB:Q80VA5-1, 2-1289, Gly-2, MOD:00068 located_in GO:0055037 recycling endosome PMID:19805030 EXP NCBITaxon:10090 UniProtKB:Q80VA5-1 20120702 PRO:HJD PR:000028854 1-aminocyclopropane-1-carboxylate synthase 6 phosphorylated 1 (Arabidopsis thaliana) At-ACS6/Phos:1|AtACS6 phosphorylated|UniProtKB:Q9SAR0, Ser-480/Ser-483/Ser-488, MOD:00046 acts_upstream_of_or_within GO:0009693 ethylene biosynthetic process PMID:15539472 EXP NCBITaxon:3702 UniProtKB:Q9SAR0-1 20120522 PRO:PD Kinase=MPK6 [PR:Q39026]. Phosphorylation promotes protein stability [PMID:18182027] PR:000028854 1-aminocyclopropane-1-carboxylate synthase 6 phosphorylated 1 (Arabidopsis thaliana) At-ACS6/Phos:1|AtACS6 phosphorylated|UniProtKB:Q9SAR0, Ser-480/Ser-483/Ser-488, MOD:00046 acts_upstream_of_or_within GO:0010365 positive regulation of ethylene biosynthetic process PMID:15539472|PMID:18182027 EXP NCBITaxon:3702 UniProtKB:Q9SAR0-1 20140402 PRO:LVM PR:000028859 1-aminocyclopropane-1-carboxylate synthase 2 phosphorylated 1 (Arabidopsis thaliana) At-ACS2/Phos:1|AtACS2 phosphorylated|UniProtKB:Q06402-1, Ser-483/Ser-488/Ser-491, MOD:00046 acts_upstream_of_or_within GO:0009693 ethylene biosynthetic process PMID:15539472 EXP NCBITaxon:3702 UniProtKB:Q06402-1 20120522 PRO:PD Kinase=MPK6 [PR:Q39026]. Phosphorylation promotes protein stability. PR:000028859 1-aminocyclopropane-1-carboxylate synthase 2 phosphorylated 1 (Arabidopsis thaliana) At-ACS2/Phos:1|AtACS2 phosphorylated|UniProtKB:Q06402-1, Ser-483/Ser-488/Ser-491, MOD:00046 acts_upstream_of_or_within GO:0010365 positive regulation of ethylene biosynthetic process PMID:15539472|PMID:18182027 EXP NCBITaxon:3702 UniProtKB:Q06402-1 20140402 PRO:LVM PR:000028874 mitogen-activated protein kinase 6 phosphorylated 1 (Arabidopsis thaliana) activated atMPK6|At-MPK6/Phos:1|atMPK6 phosphorylated|UniProtKB:Q39026, Thr-221, MOD:00047|Tyr-223, MOD:00048 enables GO:0004707 MAP kinase activity PMID:18273012 EXP NCBITaxon:3702 UniProtKB:Q39026-1 20140415 PRO:CNA Target=PR:O24606, Thr-174. PR:000028874 mitogen-activated protein kinase 6 phosphorylated 1 (Arabidopsis thaliana) activated atMPK6|At-MPK6/Phos:1|atMPK6 phosphorylated|UniProtKB:Q39026, Thr-221, MOD:00047|Tyr-223, MOD:00048 enables GO:0004707 MAP kinase activity PMID:20870959 EXP NCBITaxon:3702 UniProtKB:Q39026-1 20140415 PRO:CNA Target=PR:P11035. Evidence=ECO:0000181. PR:000028874 mitogen-activated protein kinase 6 phosphorylated 1 (Arabidopsis thaliana) activated atMPK6|At-MPK6/Phos:1|atMPK6 phosphorylated|UniProtKB:Q39026, Thr-221, MOD:00047|Tyr-223, MOD:00048 acts_upstream_of_or_within GO:0009873 ethylene-activated signaling pathway PMID:18273012 IC NCBITaxon:3702 UniProtKB:Q39026-1 20140415 PRO:CNA PR:000028971 histone acetyltransferase KAT2A isoform 1 KAT2A/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1343101 20120611 MGI:MGI PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 enables GO:0004672 protein kinase activity PMID:8978681 EXP NCBITaxon:9606 UniProtKB:P31749-1 20120716 PRO:CNA Note=Species information in Materials and methods PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 enables GO:0004674 protein serine/threonine kinase activity PMID:12138205 EXP NCBITaxon:9606 UniProtKB:P31749-1 20090709 PRO:JAN PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 enables GO:0005515 protein binding PR:O14746-1 PMID:12586360 IPI NCBITaxon:9606 UniProtKB:P31749-1 20090709 PRO:JAN PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 enables GO:0005515 protein binding PR:P41279-1 PMID:12138205 IPI NCBITaxon:9606 UniProtKB:P31749-1 20090709 PRO:JAN PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 acts_upstream_of_or_within GO:0032869 cellular response to insulin stimulus PMID:8978681 EXP NCBITaxon:9606 UniProtKB:P31749-1 20120716 PRO:CNA Note=Species information in Materials and methods PR:000028994 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human) Akt1 active form (human)|hAKT1/iso:1/Phos:1|UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046 acts_upstream_of_or_within GO:0051092 positive regulation of NF-kappaB transcription factor activity PMID:12138205 EXP NCBITaxon:9606 UniProtKB:P31749-1 20090709 PRO:JAN PR:000028998 myogenic factor 6 isoform 1 phosphorylated 1 (rat) MRF4 inactive (rat)|rMYF6/iso:1/Phos:1|UniProtKB:P19335-1, Thr-99, MOD:00047|Ser-220/Ser-221, MOD:00046 NOT enables GO:0070888 E-box binding PMID:8413199 EXP NCBITaxon:10116 UniProtKB:P19335-1 20120716 PRO:CNA Note=Species information in Materials and methods PR:000029002 histone deacetylase 4 isoform 1 phosphorylated 1 (human) HDAC4 phosphorylated (human)|hHDAC4/iso:1/Phos:1|UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046 enables GO:0071889 14-3-3 protein binding PMID:17179159 EXP NCBITaxon:9606 UniProtKB:P56524-1 20120727 PRO:CNA PR:000029002 histone deacetylase 4 isoform 1 phosphorylated 1 (human) HDAC4 phosphorylated (human)|hHDAC4/iso:1/Phos:1|UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046 located_in GO:0005737 cytoplasm PMID:17179159 EXP NCBITaxon:9606 UniProtKB:P56524-1 20120727 PRO:CNA PR:000029006 histone deacetylase 5 isoform 1 phosphorylated 1 (human) HDAC5 phosphorylated (human)|hHDAC5/iso:1/Phos:1|UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046 enables GO:0071889 14-3-3 protein binding PMID:11114197 EXP NCBITaxon:9606 UniProtKB:Q9UQL6-1 20120727 PRO:CNA PR:000029006 histone deacetylase 5 isoform 1 phosphorylated 1 (human) HDAC5 phosphorylated (human)|hHDAC5/iso:1/Phos:1|UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046 located_in GO:0005737 cytoplasm PMID:11114197 EXP NCBITaxon:9606 UniProtKB:Q9UQL6-1 20120727 PRO:CNA PR:000029006 histone deacetylase 5 isoform 1 phosphorylated 1 (human) HDAC5 phosphorylated (human)|hHDAC5/iso:1/Phos:1|UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046 acts_upstream_of_or_within GO:0007519 skeletal muscle tissue development PMID:11509672 EXP NCBITaxon:9606 UniProtKB:Q9UQL6-1 20120727 PRO:CNA PR:000029010 myocyte-specific enhancer factor 2A isoform 1 phosphorylated 1 (human) hMEF2A/iso:1/Phos:1|MEF2A phosphorylated (human)|UniProtKB:Q02078-1, Thr-312/Thr-319, MOD:00047|Ser-355, MOD:00046 enables GO:0001070 RNA-binding transcription regulator activity PMID:10849446 EXP NCBITaxon:9606 UniProtKB:Q02078-1 20120727 PRO:CNA PR:000029010 myocyte-specific enhancer factor 2A isoform 1 phosphorylated 1 (human) hMEF2A/iso:1/Phos:1|MEF2A phosphorylated (human)|UniProtKB:Q02078-1, Thr-312/Thr-319, MOD:00047|Ser-355, MOD:00046 acts_upstream_of_or_within GO:0007173 epidermal growth factor receptor signaling pathway PMID:10849446 EXP NCBITaxon:9606 UniProtKB:Q02078-1 20120727 PRO:CNA PR:000029016 myocyte-specific enhancer factor 2D isoform 2 phosphorylated 1 (mouse) mMEF2D/iso:2/Phos:1|UniProtKB:Q63943-2, Ser-179, MOD:00046 enables GO:0001070 RNA-binding transcription regulator activity PMID:10849446 EXP NCBITaxon:10090 UniProtKB:Q63943-2 20120727 PRO:CNA PR:000029016 myocyte-specific enhancer factor 2D isoform 2 phosphorylated 1 (mouse) mMEF2D/iso:2/Phos:1|UniProtKB:Q63943-2, Ser-179, MOD:00046 acts_upstream_of_or_within GO:0007173 epidermal growth factor receptor signaling pathway PMID:10849446 EXP NCBITaxon:10090 UniProtKB:Q63943-2 20120727 PRO:CNA PR:000029018 eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat) PHAS-I phosphorylated (rat)|rEIF4EBP1/iso:1/Phos:2|UniProtKB:Q62622-1, Ser-64, MOD:00046 NOT enables GO:0031369 translation initiation factor binding PMID:7939721 EXP NCBITaxon:10116 UniProtKB:Q62622-1 20120727 PRO:CNA PR:000029022 histone H1.5, initiator methionine removed phosphorylated 1 (human) hHIST1H1B/InitMet-/Phos:1|PRO_0000195909, Thr-11, MOD:00047|MOD:00696|UniProtKB:P16401, 2-226, Thr-11, MOD:00047|MOD:00696 enables GO:0003682 chromatin binding PMID:19136008 EXP NCBITaxon:9606 UniProtKB:P16401-1 20120727 PRO:CNA PR:000029022 histone H1.5, initiator methionine removed phosphorylated 1 (human) hHIST1H1B/InitMet-/Phos:1|PRO_0000195909, Thr-11, MOD:00047|MOD:00696|UniProtKB:P16401, 2-226, Thr-11, MOD:00047|MOD:00696 located_in GO:0005634 nucleus PMID:19136008 EXP NCBITaxon:9606 UniProtKB:P16401-1 20120727 PRO:CNA PR:000029022 histone H1.5, initiator methionine removed phosphorylated 1 (human) hHIST1H1B/InitMet-/Phos:1|PRO_0000195909, Thr-11, MOD:00047|MOD:00696|UniProtKB:P16401, 2-226, Thr-11, MOD:00047|MOD:00696 acts_upstream_of_or_within GO:0140014 mitotic nuclear division PMID:19136008 EXP NCBITaxon:9606 UniProtKB:P16401-1 20120727 PRO:CNA PR:000029162 myoblast determination protein 1 phosphorylated 1 (mouse) mMYOD1/Phos:1|myod phosphorylated (mouse)|myod1 phosphorylated (mouse)|UniProtKB:P10085, Ser-199/Ser-200, MOD:00046 decreased enables GO:0003700 DNA-binding transcription factor activity PR:000029164 PMID:20026657 EXP NCBITaxon:10090 UniProtKB:P10085-1 20120815 PRO:CNA Kinase=MAPK12 [PR:O08911; PR:000010153] PR:000029162 myoblast determination protein 1 phosphorylated 1 (mouse) mMYOD1/Phos:1|myod phosphorylated (mouse)|myod1 phosphorylated (mouse)|UniProtKB:P10085, Ser-199/Ser-200, MOD:00046 increased enables GO:0001046 core promoter sequence-specific DNA binding PR:000029164 PMID:20026657 EXP NCBITaxon:10090 UniProtKB:P10085-1 20120815 PRO:CNA Kinase=MAPK12 [PR:O08911; PR:000010153] PR:000029187 ribosomal protein S6 kinase alpha MAPK-activated protein kinase-1|MAPKAP-K1|p90 ribosomal S6 kinase|p90RSK|ribosomal protein S6 kinase II acts_upstream_of_or_within GO:0006468 protein phosphorylation PIRSF:PIRSF000606 ISS PIRSF:PIRSF000606 PIRSF:PIRSF000606 20120820 PRO:CNA PR:000029187 ribosomal protein S6 kinase alpha MAPK-activated protein kinase-1|MAPKAP-K1|p90 ribosomal S6 kinase|p90RSK|ribosomal protein S6 kinase II acts_upstream_of_or_within GO:0070371 ERK1 and ERK2 cascade PIRSF:PIRSF000606 ISS PIRSF:PIRSF000606 PIRSF:PIRSF000606 20120820 PRO:CNA PR:000029911 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 1 (frog) frog-BUB1/Phos:1|xBUB1 phosphorylated increased enables GO:0016301 kinase activity PR:000029917 PMID:11231148 EXP NCBITaxon:8355 UniProtKB:Q98UH3 20120912 PRO:KER Timing=Meiosis I (prophase I, metaphase I, anaphase I, telophase I), Meiosis II (prophase II, metaphase II). PR:000029956 small conductance calcium-activated potassium channel protein 3 sequence variant 1 (human) hKCNN3/var:1|SKCa3Delta (human) located_in GO:0005634 nucleus PMID:11395478 IDA NCBITaxon:9606 20080601 PRO:CNA PR:000029956 small conductance calcium-activated potassium channel protein 3 sequence variant 1 (human) hKCNN3/var:1|SKCa3Delta (human) NOT enables GO:0015269 calcium-activated potassium channel activity PMID:11395478 IDA NCBITaxon:9606 20080601 PRO:CNA PR:000029959 smad9 isoform 3 (human) hSMAD9/iso:3|SMAD8b (human) enables GO:0046332 SMAD binding PMID:10583507 IDA NCBITaxon:9606 HGNC:6774 20080301 PRO:CNA Note=Sequence not deposited in any database PR:000029959 smad9 isoform 3 (human) hSMAD9/iso:3|SMAD8b (human) located_in GO:0005737 cytoplasm PMID:10583507 IDA NCBITaxon:9606 HGNC:6774 20080301 PRO:CNA Note=Sequence not deposited in any database PR:000029959 smad9 isoform 3 (human) hSMAD9/iso:3|SMAD8b (human) acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:10583507 IDA NCBITaxon:9606 HGNC:6774 20080301 PRO:CNA Note=Sequence not deposited in any database PR:000029962 smad5 isoform 2 (human) hSMAD5/iso:2 NOT enables GO:0046332 SMAD binding PMID:10845932 IDA NCBITaxon:9606 HGNC:6771 20080301 PRO:CNA PR:000030192 catenin beta-1 isoform 1 phosphorylated 1 (human) hCTNNB1/iso:1/Phos:1|UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046 acts_upstream_of_or_within GO:0016055 Wnt signaling pathway PMID:22369945 EXP NCBITaxon:9606 UniProtKB:P35222-1 20121016 PRO:IC Note=Phosphorylation at Ser-663 found in human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. PR:000030192 catenin beta-1 isoform 1 phosphorylated 1 (human) hCTNNB1/iso:1/Phos:1|UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046 increased enables GO:0003713 transcription coactivator activity PR:000002862 PMID:22369945 EXP NCBITaxon:9606 UniProtKB:P35222-1 20121016 PRO:IC Note=Phosphorylation at Ser-663 found in human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. PR:000035362 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:1|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-620, MOD:00047 increased enables GO:0005515 protein binding PR:000035373 PR:P53350 PMID:17785528 IPI NCBITaxon:9606 UniProtKB:O60566 20121023 PRO:KER PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human) cdc20 unphosphorylated (human)|hCDC20/PhosRes- enables GO:0004842 ubiquitin-protein transferase activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human) cdc20 unphosphorylated (human)|hCDC20/PhosRes- enables GO:0005515 protein binding PR:O60566 PMID:15525512 IPI NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human) cdc20 unphosphorylated (human)|hCDC20/PhosRes- enables GO:0005515 protein binding PR:Q13257 PMID:15525512 IPI NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human) cdc20 unphosphorylated (human)|hCDC20/PhosRes- located_in GO:0000776 kinetochore PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human) cdc20 unphosphorylated (human)|hCDC20/PhosRes- acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human) cdc20 phosphorylated (human)|hCDC20/Phos:1|UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 enables GO:0005515 protein binding PR:O60566 PMID:15525512 IPI NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human) cdc20 phosphorylated (human)|hCDC20/Phos:1|UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 enables GO:0005515 protein binding PR:Q13257 PMID:15525512 IPI NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human) cdc20 phosphorylated (human)|hCDC20/Phos:1|UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 located_in GO:0000776 kinetochore PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER Timing=Spindle disruption (nocodazole). PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human) cdc20 phosphorylated (human)|hCDC20/Phos:1|UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 decreased enables GO:0004842 ubiquitin-protein transferase activity PR:000035369 PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human) cdc20 phosphorylated (human)|hCDC20/Phos:1|UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035369 PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q12834 20121023 PRO:KER PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- enables GO:0005515 protein binding PR:000035669 PMID:19503101 IPI NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- located_in GO:0000776 kinetochore PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- located_in GO:0005813 centrosome PMID:19503101 EXP NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- acts_upstream_of_or_within GO:0001933 negative regulation of protein phosphorylation PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER Target=PR:O14777. PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- acts_upstream_of_or_within GO:0010826 negative regulation of centrosome duplication PMID:19503101 EXP NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER PR:000035373 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) hBUB1B/PhosRes- acts_upstream_of_or_within GO:0033673 negative regulation of kinase activity PMID:19503101 EXP NCBITaxon:9606 UniProtKB:O60566 20130102 PRO:KER Target=PR:P53350. PR:000035386 GerQ cross-linked complex (Bacillus subtilis subsp. subtilis str. 168) located_in GO:0031160 spore wall PMID:16936016 EXP NCBITaxon:224308 UniProtKB:P39620 20121001 PRO:KL PR:000035391 protein BRASSINAZOLE-RESISTANT 2 phosphorylated 1 (Arabidopsis thaliana) At-BZR2/Phos:1|AtBES1-p|UniProtKB:Q9LN63-1, Ser-101/Ser-109/Ser-113/Ser-117/Ser-121/Ser-125/Ser-129/Ser-133/Ser-137/Ser-171, MOD:00046|Thr-105/Thr-175, MOD:00047 enables GO:0071889 14-3-3 protein binding PR:P48348 PMID:20387034 IPI NCBITaxon:3702 UniProtKB:Q9LN63 20121031 PRO:LVM PR:000035391 protein BRASSINAZOLE-RESISTANT 2 phosphorylated 1 (Arabidopsis thaliana) At-BZR2/Phos:1|AtBES1-p|UniProtKB:Q9LN63-1, Ser-101/Ser-109/Ser-113/Ser-117/Ser-121/Ser-125/Ser-129/Ser-133/Ser-137/Ser-171, MOD:00046|Thr-105/Thr-175, MOD:00047 located_in GO:0005737 cytoplasm PMID:20387034 EXP NCBITaxon:3702 UniProtKB:Q9LN63 20121031 PRO:LVM PR:000035391 protein BRASSINAZOLE-RESISTANT 2 phosphorylated 1 (Arabidopsis thaliana) At-BZR2/Phos:1|AtBES1-p|UniProtKB:Q9LN63-1, Ser-101/Ser-109/Ser-113/Ser-117/Ser-121/Ser-125/Ser-129/Ser-133/Ser-137/Ser-171, MOD:00046|Thr-105/Thr-175, MOD:00047 decreased acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PR:000035745 PMID:20387034 EXP NCBITaxon:3702 UniProtKB:Q9LN63 20130430 PRO:CNA PR:000035398 BUB1B:APC:EB1 complex (frog) BUBR1:APC:EB1 complex acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:17709426 EXP NCBITaxon:8355 20121121 PRO:KER PR:000035404 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog) frog-BUB1/Phos:3|UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047|Ser-500/Ser-634, MOD:00046|xBUB1 hyperphosphorylated acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:15241477 EXP NCBITaxon:8355 UniProtKB:Q6GPC9-1 20121105 PRO:KER PR:000035404 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog) frog-BUB1/Phos:3|UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047|Ser-500/Ser-634, MOD:00046|xBUB1 hyperphosphorylated acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:15241477 EXP NCBITaxon:8355 UniProtKB:Q6GPC9-1 20121105 PRO:KER Target=PR:P79935. PR:000035404 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog) frog-BUB1/Phos:3|UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047|Ser-500/Ser-634, MOD:00046|xBUB1 hyperphosphorylated acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:15241477 EXP NCBITaxon:8355 UniProtKB:Q6GPC9-1 20121105 PRO:KER Target=PR:Q6GPD1. PR:000035404 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog) frog-BUB1/Phos:3|UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047|Ser-500/Ser-634, MOD:00046|xBUB1 hyperphosphorylated acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:15241477 EXP NCBITaxon:8355 UniProtKB:Q6GPC9-1 20121105 PRO:KER Target=PR:Q9YGY3-2. PR:000035404 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 3 (frog) frog-BUB1/Phos:3|UniProtKB:Q6GPC9, Thr-493/Thr-650, MOD:00047|Ser-500/Ser-634, MOD:00046|xBUB1 hyperphosphorylated increased enables GO:0004672 protein kinase activity PR:000029917 PMID:15241477 EXP NCBITaxon:8355 UniProtKB:Q6GPC9-1 20121105 PRO:KER PR:000035405 mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form (human) hBUB1/PhosRes- located_in GO:0000776 kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O43683 20130102 PRO:KER Timing=spindle disruption (nocodazole). PR:000035405 mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form (human) hBUB1/PhosRes- NOT enables GO:0005515 protein binding PR:P53350 PMID:16760428 IPI NCBITaxon:9606 UniProtKB:O43683 20130102 PRO:KER Timing=spindle disruption (nocodazole). PR:000035407 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 4 (human) hBUB1 phosphorylated|hBUB1/Phos:4 increased enables GO:0004672 protein kinase activity PR:000035405 PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:000035410 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 (Schizosaccharomyces pombe 972h-) Spom972h-BUB1/Phos:5 acts_upstream_of_or_within GO:0007094 mitotic spindle assembly checkpoint signaling PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20121105 PRO:KER PR:000035410 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 (Schizosaccharomyces pombe 972h-) Spom972h-BUB1/Phos:5 acts_upstream_of_or_within GO:0045143 homologous chromosome segregation PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20121105 PRO:KER PR:000035411 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-) Spom972h-BUB1/Phos:6|UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046) located_in GO:0000776 kinetochore PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20121105 PRO:KER Timing=spindle disruption. PR:000035411 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-) Spom972h-BUB1/Phos:6|UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046) acts_upstream_of_or_within GO:0007094 mitotic spindle assembly checkpoint signaling PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20121105 PRO:KER PR:000035411 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-) Spom972h-BUB1/Phos:6|UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046) acts_upstream_of_or_within GO:0045143 homologous chromosome segregation PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20121105 PRO:KER PR:000035412 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human) hBUB1/Phos:7|UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=PR:Q9NQS7. PR:000035412 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human) hBUB1/Phos:7|UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047 increased enables GO:0005515 protein binding PR:000035414 PR:Q9NQS7 PMID:16760428 IPI NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Timing=Mitosis and spindle disruption (nocodazole). PR:000035419 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 1 (yeast) BUB1p phosphorylated|UniProtKB:P41695, Thr-566, MOD:00047|yBUB1/Phos:CDK-1 NOT acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:21298086 EXP NCBITaxon:559292 UniProtKB:P41695 20121105 PRO:KER PR:000035421 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 10 (human) hBUB1 phosphorylated|hBUB1/Phos:10|UniProtKB:O43683-1, Ser-314, MOD:00046 located_in GO:0035861 site of double-strand break PMID:22071147 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:000035421 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 10 (human) hBUB1 phosphorylated|hBUB1/Phos:10|UniProtKB:O43683-1, Ser-314, MOD:00046 acts_upstream_of_or_within GO:0006281 DNA repair PMID:22071147 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:000035421 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 10 (human) hBUB1 phosphorylated|hBUB1/Phos:10|UniProtKB:O43683-1, Ser-314, MOD:00046 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:22099307 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:000035421 mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 10 (human) hBUB1 phosphorylated|hBUB1/Phos:10|UniProtKB:O43683-1, Ser-314, MOD:00046 increased enables GO:0004672 protein kinase activity PR:000035405 PMID:22071147 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=PR:000044898. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 located_in GO:0000779 condensed chromosome, centromeric region PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20130117 PRO:KER Timing=Metaphase. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 located_in GO:0000922 spindle pole PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER Timing=Prometaphase and metaphase. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 located_in GO:0005694 chromosome PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER Timing=Prophase. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 located_in GO:0030496 midbody PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER Timing=Telophase. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 located_in GO:0051233 spindle midzone PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER Timing=Snaphase. PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 increased enables GO:0004672 protein kinase activity PR:000035452 PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER PR:000035423 serine-protein kinase ATM phosphorylated 2 (human) hATM/Phos:2|UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035452 PMID:22099307 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER PR:000035426 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog) BUBR1 phosphorylated (frog)|frog-BUB1B/Phos:1|UniProtKB:Q8JGT8, Thr-605, MOD:00047|xBUBR1 phosphorylated acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:17998400 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20121105 PRO:KER PR:000035426 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog) BUBR1 phosphorylated (frog)|frog-BUB1B/Phos:1|UniProtKB:Q8JGT8, Thr-605, MOD:00047|xBUBR1 phosphorylated acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17998400 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20121105 PRO:KER Target=PR:P70032. PR:000035426 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog) BUBR1 phosphorylated (frog)|frog-BUB1B/Phos:1|UniProtKB:Q8JGT8, Thr-605, MOD:00047|xBUBR1 phosphorylated acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17998400 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20121105 PRO:KER Target=PR:P79935. PR:000035426 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog) BUBR1 phosphorylated (frog)|frog-BUB1B/Phos:1|UniProtKB:Q8JGT8, Thr-605, MOD:00047|xBUBR1 phosphorylated increased enables GO:0005515 protein binding PR:000035425 PR:P70032 PMID:17998400 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) enables GO:0005515 protein binding PR:Q12834 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) located_in GO:0000776 kinetochore PMID:17785528 EXP NCBITaxon:9606 UniProtKB:O60566 20130117 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) acts_upstream_of_or_within GO:0006974 DNA damage response PMID:18440313 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) increased enables GO:0004672 protein kinase activity PR:000035425 PMID:17376779 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) increased enables GO:0005515 protein binding PR:000035425 PR:O43683 PMID:11792804 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) increased enables GO:0005515 protein binding PR:000035425 PR:Q15172 PMID:23079597 IPI NCBITaxon:9606 UniProtKB:O60566 20130201 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) increased acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PR:000035425 PMID:17785528 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:2|hBUBR1 phosphorylated|UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047) increased acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PR:000035425 PMID:17376779|PMID:17785528 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035430 mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form (frog) frog-BUB1B/Phos:2|UniProtKB:Q8JGT8, Thr-605, MOD:00047|MOD:00696 increased enables GO:0004672 protein kinase activity PR:000035425 PMID:17998400 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20121105 PRO:KER PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 located_in GO:0000776 kinetochore PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 decreased acts_upstream_of_or_within GO:0001933 negative regulation of protein phosphorylation PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:O14777. PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 increased acts_upstream_of_or_within GO:0007059 chromosome segregation PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 increased acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:Q13257. PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 increased acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:Q9Y6D9. PR:000035432 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:3|hBUBR1 phosphorylated|UniProtKB:O60566-1, Thr-608, MOD:00047 increased acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PR:000035373 PMID:22801780 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035435 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:4|hBUBR1 phosphorylated|UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046 located_in GO:0000776 kinetochore PMID:19015317 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=prophase, prometaphase, metaphase. PR:000035435 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:4|hBUBR1 phosphorylated|UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046 increased acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PR:000035373 PMID:19015317|PMID:20016069 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035435 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human) BUBR1 phosphorylated (human)|hBUB1B/Phos:4|hBUBR1 phosphorylated|UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046 increased acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PR:000035373 PMID:20016069 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:000035437 mitotic checkpoint protein BUB3 phosphorylated 1 (human) hBUB3/Phos:1|UniProtKB:O43684, Ser-18, MOD:00046 increased acts_upstream_of_or_within GO:0012501 programmed cell death PR:000035454 PMID:20057499 EXP NCBITaxon:9606 UniProtKB:O43684 20121105 PRO:KER PR:000035442 cell division cycle protein 20 homolog phosphorylated 3 (human) cdc20 phosphorylated (human)|hCDC20/Phos:3|p55CDC phsphorylated (human) decreased enables GO:0005515 protein binding PR:000035369 PR:O60566 PMID:22566641 IPI NCBITaxon:9606 UniProtKB:Q12834 20121105 PRO:KER PR:000035444 cell division cycle protein 20 homolog phosphorylated 4 (frog) Fizzy1 phosphorylated (frog)|frog-CDC20/Phos:4|UniProtKB:Q6DFD4, Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047 increased enables GO:0005515 protein binding PR:000035628 PR:O60566 PMID:12855955 IPI NCBITaxon:8355 UniProtKB:O93289 20121105 PRO:KER PR:000035444 cell division cycle protein 20 homolog phosphorylated 4 (frog) Fizzy1 phosphorylated (frog)|frog-CDC20/Phos:4|UniProtKB:Q6DFD4, Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047 increased enables GO:0005515 protein binding PR:000035628 PR:P79935 PMID:12855955 IPI NCBITaxon:8355 UniProtKB:O93289 20121105 PRO:KER PR:000035444 cell division cycle protein 20 homolog phosphorylated 4 (frog) Fizzy1 phosphorylated (frog)|frog-CDC20/Phos:4|UniProtKB:Q6DFD4, Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035628 PMID:12855955 EXP NCBITaxon:8355 UniProtKB:O93289 20121105 PRO:KER Target=PR:000035369. PR:000035446 cellular tumor antigen p53 isoform 1 phosphorylated 1 (human) hTP53/iso:1/Phos:1|p53S15 (human)|UniProtKB:P04637-1, Ser-15, MOD:00046 located_in GO:0005634 nucleus PMID:11602639 EXP NCBITaxon:9606 UniProtKB:P04637-1 20090717 PRO:CL Note=HIV-1-Env-induced syncytium formation leads to apoptosis via a pathway that involves p53S15 phosphorylation by mTOR/FRAP. PR:000035446 cellular tumor antigen p53 isoform 1 phosphorylated 1 (human) hTP53/iso:1/Phos:1|p53S15 (human)|UniProtKB:P04637-1, Ser-15, MOD:00046 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11602639 EXP NCBITaxon:9606 UniProtKB:P04637-1 20090717 PRO:CL Note=HIV-1-Env-induced syncytium formation leads to apoptosis via a pathway that involves p53S15 phosphorylation by mTOR/FRAP. PR:000035449 cell division cycle protein 27 phosphorylated 1 (human) hCDC27/Phos:1 increased enables GO:0005515 protein binding PR:000035450 PR:O60566 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:P30260 20121124 PRO:KER PR:000035458 T-complex protein 1 subunit epsilon isoform 1 phosphorylated 1 (mouse) mCCT5/iso:1/Phos:1|UniProtKB:P80316-1, Ser-270, MOD:00046 part_of GO:0002199 zona pellucida receptor complex MGI_ref:5295912|PMID:21880732 IDA NCBITaxon:10090 MGI:107185 20121109 MGI:MGI PR:000035460 T-complex protein 1 subunit eta isoform 1 phosphorylated 1 (mouse) mCCT7/iso:1/Phos:1|UniProtKB:P80313-1, Thr-57, MOD:00047|Ser-59, MOD:00046 part_of GO:0002199 zona pellucida receptor complex MGI_ref:5295912|PMID:21880732 IDA NCBITaxon:10090 MGI:107184 20121109 MGI:MGI PR:000035483 Purkinje cell protein 2 isoform 2 PCP2/iso:2 located_in GO:0043025 neuronal cell body MGI_ref:3817370|PMID:18768681 IDA NCBITaxon:10090 MGI:97508 20121114 MGI:MGI part_of(MA:0000276),part_of(CL:0000749) PR:000035486 breast cancer type 2 susceptibility protein phosphorylated 1 (human) hBRCA2/Phos:1 located_in GO:0005634 nucleus PMID:10749118 EXP NCBITaxon:9606 UniProtKB:P51587 20121112 PRO:KER PR:000035503 spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast) UniProtKB:P47074, Ser-303/Ser-337, MOD:00046|yMAD3/Phos:2 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035506 PMID:17504936 EXP NCBITaxon:4932 UniProtKB:P47074 20121120 PRO:KER PR:000035509 interleukin-24 isoform 2 IL24/iso:2 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:3821693|PMID:18708357 IGI NCBITaxon:10090 UniProtKB:Q925S4-1 MGI:2135548 20130624 MGI:MGI PR:000035509 interleukin-24 isoform 2 IL24/iso:2 acts_upstream_of_or_within GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MGI_ref:3821693|PMID:18708357 IGI NCBITaxon:10090 UniProtKB:Q925S4-1 MGI:2135548 20130624 MGI:MGI PR:000035521 serine/threonine-protein kinase haspin phosphorylated 1 (human) hHASPIN/Phos:1|UniProtKB:Q8TF76, Ser-93/Ser-108/Ser-143, MOD:00046 enables GO:0004672 protein kinase activity PMID:21658950 EXP NCBITaxon:9606 UniProtKB:Q8TF76 20121121 PRO:KER PR:000035521 serine/threonine-protein kinase haspin phosphorylated 1 (human) hHASPIN/Phos:1|UniProtKB:Q8TF76, Ser-93/Ser-108/Ser-143, MOD:00046 located_in GO:0005694 chromosome PMID:21658950 EXP NCBITaxon:9606 UniProtKB:Q8TF76 20121121 PRO:KER PR:000035521 serine/threonine-protein kinase haspin phosphorylated 1 (human) hHASPIN/Phos:1|UniProtKB:Q8TF76, Ser-93/Ser-108/Ser-143, MOD:00046 increased enables GO:0004672 protein kinase activity PR:000035523 PMID:21658950 EXP NCBITaxon:9606 UniProtKB:Q8TF76 20121121 PRO:KER Target=PR:000035524. PR:000035521 serine/threonine-protein kinase haspin phosphorylated 1 (human) hHASPIN/Phos:1|UniProtKB:Q8TF76, Ser-93/Ser-108/Ser-143, MOD:00046 increased acts_upstream_of_or_within GO:0034502 protein localization to chromosome PR:000035523 PMID:21658950 EXP NCBITaxon:9606 UniProtKB:Q8TF76 20121121 PRO:KER Target=PR:Q96GD4. PR:000035525 histone H3, initiator methionine removed phosphorylated 1 (human) hH3(any)/InitMet-/Phos:1|hH3T3ph|human histone H3 Thr-3 located_in GO:0000779 condensed chromosome, centromeric region PMID:21658950 EXP NCBITaxon:9606 20130116 PRO:KER PR:000035525 histone H3, initiator methionine removed phosphorylated 1 (human) hH3(any)/InitMet-/Phos:1|hH3T3ph|human histone H3 Thr-3 increased enables GO:0005515 protein binding PR:000035690 PR:O15392 PMID:21658950 IPI NCBITaxon:9606 20130116 PRO:KER PR:000035525 histone H3, initiator methionine removed phosphorylated 1 (human) hH3(any)/InitMet-/Phos:1|hH3T3ph|human histone H3 Thr-3 increased acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PR:000035690 PMID:21658950 EXP NCBITaxon:9606 20130116 PRO:KER Target=PR:Q96GD4. Target=PR:Q9NQS7. Target=PR:O15392. Target=PR:Q53HL2. PR:000035527 inner centromere protein phosphorylated 1 (human) hINCENP/Phos:1|UniProtKB:Q9NQS7, Thr-892, MOD:00047|Ser-893/Ser-894, MOD:00046 increased acts_upstream_of_or_within GO:0033674 positive regulation of kinase activity PR:000035529 PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q9NQS7 20121121 PRO:KER Target=PR:Q96GD4. PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased enables GO:0005515 protein binding PR:000035538 PR:P26449 PMID:22521787 IPI NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased enables GO:0005515 protein binding PR:000035538 PR:P41695 PMID:22521787 IPI NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased acts_upstream_of_or_within GO:0007059 chromosome segregation PR:000035538 PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035538 PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PR:000035538 PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER Target=PR:P26449. PR:000035536 spindle pole body component SPC105 phosphorylated 1 (yeast) UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047|ySPC105/Phos:1 increased acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PR:000035538 PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P53148 20121121 PRO:KER Target=PR:P41695. PR:000035549 segment polarity protein dishevelled homolog DVL-2 phosphorylated 1 (human) hDVL2/Phos:1|UniProtKB:O14641, Thr-206, MOD:00047 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121124 PRO:KER PR:000035549 segment polarity protein dishevelled homolog DVL-2 phosphorylated 1 (human) hDVL2/Phos:1|UniProtKB:O14641, Thr-206, MOD:00047 increased acts_upstream_of_or_within GO:0051294 establishment of spindle orientation PR:000035550 PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121124 PRO:KER PR:000035550 segment polarity protein dishevelled homolog DVL-2 unphosphorylated form (human) hDVL2/PhosRes- located_in GO:0000776 kinetochore PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20130102 PRO:KER PR:000035550 segment polarity protein dishevelled homolog DVL-2 unphosphorylated form (human) hDVL2/PhosRes- acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20130102 PRO:KER PR:000035558 kinetochore scaffold 1 isoform 2 phosphorylated 1 (human) hKNL1/iso:2/Phos:1|UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046 increased acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PR:000035560 PMID:22660415 EXP NCBITaxon:9606 UniProtKB:Q8NG31-2 20121124 PRO:KER Target=PR:O43683. PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse) DISC1 phosphorylated|mDISC1/iso:1/Phos:1|UniProtKB:Q811T9-1, Ser-710, MOD:00046 enables GO:0005515 protein binding PR:Q3V3N7 MGI_ref:5002731|PMID:21471969 IPI NCBITaxon:10090 MGI:2447658 20121205 MGI:MGI occurs_in(EMAP:11619) PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse) DISC1 phosphorylated|mDISC1/iso:1/Phos:1|UniProtKB:Q811T9-1, Ser-710, MOD:00046 located_in GO:0005813 centrosome MGI_ref:5002731|PMID:21471969 IDA NCBITaxon:10090 MGI:2447658 20121205 MGI:MGI part_of(CL:0000530) PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse) DISC1 phosphorylated|mDISC1/iso:1/Phos:1|UniProtKB:Q811T9-1, Ser-710, MOD:00046 acts_upstream_of_or_within GO:0008104 protein localization MGI_ref:5002731|PMID:21471969 IDA NCBITaxon:10090 MGI:2447658 20121205 MGI:MGI PR:000035640 glutamate receptor-interacting protein 1 isoform 2 palmitoylated 1 (mouse) mGRIP1/iso:2/Palm:1|UniProtKB:Q925T6-2, Cys-11, MOD:00115 located_in GO:0055037 recycling endosome MGI_ref:5315188|PMID:22325201 IMP NCBITaxon:10090 MGI:1921303 20121214 MGI:MGI part_of(CL:0002608) PR:000035652 cystin-1 isoform 1, N-terminal myristoylated form (mouse) mCYS1/iso:1/MyrRes+|PRO_0000261178, Gly-2, MOD:00068|UniProtKB:Q8R4T1-1, 2-145, Gly-2, MOD:00068 located_in GO:0005930 axoneme MGI_ref:4461844|PMID:19850956 IMP NCBITaxon:10090 MGI:2177632 20121226 MGI:MGI PR:000035652 cystin-1 isoform 1, N-terminal myristoylated form (mouse) mCYS1/iso:1/MyrRes+|PRO_0000261178, Gly-2, MOD:00068|UniProtKB:Q8R4T1-1, 2-145, Gly-2, MOD:00068 located_in GO:0045121 membrane raft MGI_ref:4461844|PMID:19850956 IDA NCBITaxon:10090 MGI:2177632 20121220 MGI:MGI PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse) mDISC1/iso:1/PhosRes- enables GO:0005515 protein binding PR:Q9WV60 MGI_ref:5002731|PMID:21471969 IPI NCBITaxon:10090 MGI:2447658 20121205 MGI:MGI occurs_in(EMAP:6018) PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse) mDISC1/iso:1/PhosRes- acts_upstream_of_or_within GO:0060070 canonical Wnt signaling pathway MGI_ref:5002731|PMID:21471969 IMP NCBITaxon:10090 MGI:2447658 20121205 MGI:MGI occurs_in(EMAP:6018) PR:000035661 aurora kinase B unphosphorylated form (human) hAURKB/PhosRes- enables GO:0005515 protein binding PR:Q9NQS7 PMID:22024163 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035661 aurora kinase B unphosphorylated form (human) hAURKB/PhosRes- located_in GO:0000776 kinetochore PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 enables GO:0005515 protein binding PR:Q9NQS7 PMID:22024163 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 located_in GO:0000776 kinetochore PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER Timing=prometaphase and metaphase. PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 increased enables GO:0004672 protein kinase activity PR:000035661 PMID:17276342|PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 increased acts_upstream_of_or_within GO:0007059 chromosome segregation PR:000035661 PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 increased acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PR:000035661 PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035663 aurora kinase B phosphorylated 1 (human) hAURKB active form|hAURKB/Phos:1|UniProtKB:Q96GD4, Ser-331, MOD:00046 increased acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PR:000035661 PMID:22024163 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20130116 PRO:KER PR:000035696 serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse) AATYK1A palmitoylated 1 (mouse)|mAATK/iso:2/Palm:1|UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115 enables GO:0005515 protein binding PR:P12931 MGI_ref:3820458|PMID:18691334 IPI NCBITaxon:10090 MGI:1197518 20130125 MGI:MGI PR:000035696 serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse) AATYK1A palmitoylated 1 (mouse)|mAATK/iso:2/Palm:1|UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115 located_in GO:0055037 recycling endosome MGI_ref:3820458|PMID:18691334 IDA NCBITaxon:10090 MGI:1197518 20130118 MGI:MGI PR:000035700 serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse) AATYK1A phosphorylated 1 (mouse)|mAATK/iso:2/Phos:1|UniProtKB:Q80YE4-2, Ser-34, MOD:00046 located_in GO:0044295 axonal growth cone MGI_ref:5426470|PMID:22573681 IDA NCBITaxon:10090 MGI:1197518 20130122 MGI:MGI part_of(CL:0002609) PR:000035700 serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse) AATYK1A phosphorylated 1 (mouse)|mAATK/iso:2/Phos:1|UniProtKB:Q80YE4-2, Ser-34, MOD:00046 located_in GO:0048471 perinuclear region of cytoplasm MGI_ref:5426470|PMID:22573681 IDA NCBITaxon:10090 MGI:1197518 20130122 MGI:MGI part_of(CL:0002609) PR:000035700 serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse) AATYK1A phosphorylated 1 (mouse)|mAATK/iso:2/Phos:1|UniProtKB:Q80YE4-2, Ser-34, MOD:00046 located_in GO:0055037 recycling endosome MGI_ref:5426470|PMID:22573681 IDA NCBITaxon:10090 MGI:1197518 20130122 MGI:MGI part_of(CL:0002609) PR:000035700 serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse) AATYK1A phosphorylated 1 (mouse)|mAATK/iso:2/Phos:1|UniProtKB:Q80YE4-2, Ser-34, MOD:00046 acts_upstream_of_or_within GO:0030517 negative regulation of axon extension MGI_ref:5426470|PMID:22573681 IGI NCBITaxon:10090 MGI:101764 MGI:1197518 20130124 MGI:MGI regulates_o_occurs_in(CL:0002609) PR:000035700 serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse) AATYK1A phosphorylated 1 (mouse)|mAATK/iso:2/Phos:1|UniProtKB:Q80YE4-2, Ser-34, MOD:00046 acts_upstream_of_or_within GO:0030517 negative regulation of axon extension MGI_ref:5426470|PMID:22573681 IMP NCBITaxon:10090 MGI:1197518 20130122 MGI:MGI regulates_o_occurs_in(CL:0002609) PR:000035701 lipopolysaccharide-binding protein, signal peptide removed form (human) hLBP/SigPep-|LBP|PRO_0000017158|UniProtKB:P18428, 26-481 located_in GO:0005576 extracellular region Reactome:REACT_7385 EXP NCBITaxon:9606 UniProtKB:P18428 20130125 PRO:CNA PR:000035701 lipopolysaccharide-binding protein, signal peptide removed form (human) hLBP/SigPep-|LBP|PRO_0000017158|UniProtKB:P18428, 26-481 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 UniProtKB:P18428 20130125 PRO:CNA PR:000035702 CD14 molecule cleaved 2 GPI-anchored form (human) GPI-anchored form of CD14 (human)|GPI-N345-CD14 (human)|hCD14/iso:1/Clv:2/anchored|PRO_0000020885, Asn-345, MOD:00167|UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167 located_in GO:0005886 plasma membrane PMID:2779588|PMID:3385210|PMID:9665271 EXP NCBITaxon:9606 UniProtKB:P08571-1 20130125 PRO:CNA PR:000035702 CD14 molecule cleaved 2 GPI-anchored form (human) GPI-anchored form of CD14 (human)|GPI-N345-CD14 (human)|hCD14/iso:1/Clv:2/anchored|PRO_0000020885, Asn-345, MOD:00167|UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167 located_in GO:0005886 plasma membrane Reactome:REACT_7740 EXP NCBITaxon:9606 UniProtKB:P08571-1 20130125 PRO:CNA PR:000035702 CD14 molecule cleaved 2 GPI-anchored form (human) GPI-anchored form of CD14 (human)|GPI-N345-CD14 (human)|hCD14/iso:1/Clv:2/anchored|PRO_0000020885, Asn-345, MOD:00167|UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 UniProtKB:P08571-1 20130125 PRO:CNA PR:000035703 CD14 molecule cleaved 2 soluble form (human) hCD14/iso:1/Clv:2/soluble|PRO_0000020885|Secreted form of CD14 (human)|UniProtKB:P08571-1, 20-345 expressed_in CL:0000129 microglial cell PMID:24659539 EXP NCBITaxon:9606 UniProtKB:P08571-1 20140514 PRO:CNA Note=Expressed in supernatant of microglial cells PR:000035703 CD14 molecule cleaved 2 soluble form (human) hCD14/iso:1/Clv:2/soluble|PRO_0000020885|Secreted form of CD14 (human)|UniProtKB:P08571-1, 20-345 enables GO:0001530 lipopolysaccharide binding PMID:9464818 EXP NCBITaxon:9606 UniProtKB:P08571-1 20140514 PRO:CNA PR:000035703 CD14 molecule cleaved 2 soluble form (human) hCD14/iso:1/Clv:2/soluble|PRO_0000020885|Secreted form of CD14 (human)|UniProtKB:P08571-1, 20-345 located_in GO:0005576 extracellular region PMID:2779588|PMID:9665271 EXP NCBITaxon:9606 UniProtKB:P08571-1 20130125 PRO:CNA PR:000035703 CD14 molecule cleaved 2 soluble form (human) hCD14/iso:1/Clv:2/soluble|PRO_0000020885|Secreted form of CD14 (human)|UniProtKB:P08571-1, 20-345 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 UniProtKB:P08571-1 20130125 PRO:CNA PR:000035707 interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse) mIRF8/iso:1/Sumo:1|SUMOylated IRF8|UniProtKB:P23611-1, Lys-310, MOD:01149 located_in GO:0005634 nucleus MGI_ref:5448615|PMID:22942423 IDA NCBITaxon:10090 MGI:96395 20130130 MGI:MGI PR:000035707 interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse) mIRF8/iso:1/Sumo:1|SUMOylated IRF8|UniProtKB:P23611-1, Lys-310, MOD:01149 NOT acts_upstream_of_or_within GO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615|PMID:22942423 IDA NCBITaxon:10090 MGI:96395 20130130 MGI:MGI PR:000035709 interferon regulatory factor 8 isoform 1 unsumoylated form (mouse) mIRF8/iso:1/SumoRes- located_in GO:0005634 nucleus MGI_ref:5448615|PMID:22942423 IDA NCBITaxon:10090 MGI:96395 20130130 MGI:MGI PR:000035709 interferon regulatory factor 8 isoform 1 unsumoylated form (mouse) mIRF8/iso:1/SumoRes- acts_upstream_of_or_within GO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615|PMID:22942423 IDA NCBITaxon:10090 MGI:96395 20130130 MGI:MGI PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse) traf6:trif:tram:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:14530355 EXP NCBITaxon:10090 20130412 PRO:CNA PR:000035714 TNF receptor-associated factor 6 K63-polyubiquitinated 1 (human) hTRAF6/K63polyUbiq:1|K63-pUb-TRAF6|UniProtKB:Q9Y4K3, Lys-124, PR:000044772 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 UniProtKB:Q9Y4K3 20130412 PRO:CNA PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-TRAF6 (human) located_in GO:0010008 endosome membrane Reactome:REACT_25867 EXP NCBITaxon:9606 20130130 PRO:CNA PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-TRAF6 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130130 PRO:CNA PR:000035730 TAK1 kinase complex (human) TAB1:TAB2,TAB3:TAK1 (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25222 EXP NCBITaxon:9606 20140428 PRO:VS PR:000035730 TAK1 kinase complex (human) TAB1:TAB2,TAB3:TAK1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20140428 PRO:VS PR:000035730 TAK1 kinase complex (human) TAB1:TAB2,TAB3:TAK1 (human) acts_upstream_of_or_within GO:0038095 Fc-epsilon receptor signaling pathway Reactome:REACT_163936 EXP NCBITaxon:9606 20140428 PRO:VS PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) enables GO:0004674 protein serine/threonine kinase activity Reactome:REACT_26036 EXP NCBITaxon:9606 20130204 PRO:CNA PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_26036 EXP NCBITaxon:9606 20130204 PRO:CNA PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:TRAF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_26039 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:TRAF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human) K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)|pUb-TRAF6:TAB1:TAB2/TAB3:free polyubiquitin chain : phospho-TAK1 (human) located_in GO:0005829 cytosol Reactome:REACT_23131 EXP NCBITaxon:9606 20130204 PRO:CNA PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human) K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)|pUb-TRAF6:TAB1:TAB2/TAB3:free polyubiquitin chain : phospho-TAK1 (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_23131 EXP NCBITaxon:9606 20140428 PRO:VS PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human) K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human)|pUb-TRAF6:TAB1:TAB2/TAB3:free polyubiquitin chain : phospho-TAK1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_23131 EXP NCBITaxon:9606 20140428 PRO:VS PR:000035742 shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana) At-ASK7/Phos:1|Tyr200 BIN2|UniProtKB:Q39011-1, Tyr-200, MOD:00048 enables GO:0004672 protein kinase activity PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q39011 20130205 PRO:CNA PR:000035742 shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana) At-ASK7/Phos:1|Tyr200 BIN2|UniProtKB:Q39011-1, Tyr-200, MOD:00048 enables GO:0005515 protein binding PR:Q8L7U5 PMID:19734888 IPI NCBITaxon:3702 UniProtKB:Q39011 20130429 PRO:LVM PR:000035742 shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana) At-ASK7/Phos:1|Tyr200 BIN2|UniProtKB:Q39011-1, Tyr-200, MOD:00048 enables GO:0019903 protein phosphatase binding PR:000028342 PMID:21855796 IPI NCBITaxon:3702 UniProtKB:Q39011 20130205 PRO:CNA PR:000035742 shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana) At-ASK7/Phos:1|Tyr200 BIN2|UniProtKB:Q39011-1, Tyr-200, MOD:00048 enables GO:0019903 protein phosphatase binding PR:Q9LR78 PMID:19734888 IPI NCBITaxon:3702 UniProtKB:Q39011 20130429 PRO:LVM PR:000035742 shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana) At-ASK7/Phos:1|Tyr200 BIN2|UniProtKB:Q39011-1, Tyr-200, MOD:00048 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:19734888|PMID:21855796 EXP NCBITaxon:3702 UniProtKB:Q39011 20120429 PRO:LVM PR:000035749 receptor-like serine/threonine-protein kinase SD1-7 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-SD17/iso:1/Phos:1|AtpARK1 enables GO:0004674 protein serine/threonine kinase activity PMID:8811866 EXP NCBITaxon:3702 UniProtKB:Q39086-1 20130206 PRO:CNA PR:000035749 receptor-like serine/threonine-protein kinase SD1-7 isoform 1 phosphorylated 1 (Arabidopsis thaliana) At-SD17/iso:1/Phos:1|AtpARK1 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:8811866 EXP NCBITaxon:3702 UniProtKB:Q39086-1 20130206 PRO:CNA PR:000035770 catenin beta-1 isoform 1 phosphorylated 2 (human) hCTNNB1/iso:1/Phos:2|UniProtKB:P35222-1, Tyr-64, MOD:00048|Tyr-142, MOD:00048|(Tyr-331, MOD:00048 or Tyr-333, MOD:00048) located_in GO:0005634 nucleus PMID:20026641 EXP NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000035772 catenin beta-1 isoform 1 phosphorylated 3 (human) hCTNNB1/iso:1/Phos:3|UniProtKB:P35222-1, Ser-33/Ser-37/Ser-45, MOD:00046|Thr-41, MOD:00047 enables GO:0005515 protein binding PR:Q9Y297 PMID:10074433 IPI NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000035772 catenin beta-1 isoform 1 phosphorylated 3 (human) hCTNNB1/iso:1/Phos:3|UniProtKB:P35222-1, Ser-33/Ser-37/Ser-45, MOD:00046|Thr-41, MOD:00047 NOT enables GO:0005515 protein binding PR:Q9UKB1 PMID:10074433 IPI NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000035774 catenin beta-1 isoform 1 phosphorylated 4 (human) hCTNNB1/iso:1/Phos:4|UniProtKB:P35222-1, Ser-45, MOD:00046 enables GO:0005515 protein binding PR:P12830 PMID:20419129|PMID:21152425 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000035774 catenin beta-1 isoform 1 phosphorylated 4 (human) hCTNNB1/iso:1/Phos:4|UniProtKB:P35222-1, Ser-45, MOD:00046 located_in GO:0005634 nucleus PMID:20419129 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000035774 catenin beta-1 isoform 1 phosphorylated 4 (human) hCTNNB1/iso:1/Phos:4|UniProtKB:P35222-1, Ser-45, MOD:00046 increased enables GO:0005515 protein binding PR:000037813 PR:P49841 PMID:12051714|PMID:20419129|PMID:23606879 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000035776 serine/threonine-protein kinase PAK 1 phosphorylated 1 (human) hPAK1/Phos:1|UniProtKB:Q13153, Thr-423, MOD:00047 enables GO:0004674 protein serine/threonine kinase activity PMID:22369945 EXP NCBITaxon:9606 UniProtKB:Q13153 20130225 PRO:IC Target=PR:000002319. PR:000035776 serine/threonine-protein kinase PAK 1 phosphorylated 1 (human) hPAK1/Phos:1|UniProtKB:Q13153, Thr-423, MOD:00047 enables GO:0008013 beta-catenin binding PMID:22369945 EXP NCBITaxon:9606 UniProtKB:Q13153 20130225 PRO:IC Target=PR:000002319. PR:000035786 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 5 (Arabidopsis thaliana) At protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 4|At-BRI1/iso:1/Phos:5|UniProtKB:O22476-1, Ser-858/Ser-891, MOD:00046|Thr-872, MOD:00047 enables GO:0005515 protein binding PR:Q94F62-1 PMID:22184234 IPI NCBITaxon:3702 UniProtKB:O22476-1 20130304 PRO:LVM PR:000035786 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 5 (Arabidopsis thaliana) At protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 4|At-BRI1/iso:1/Phos:5|UniProtKB:O22476-1, Ser-858/Ser-891, MOD:00046|Thr-872, MOD:00047 acts_upstream_of_or_within GO:0040015 negative regulation of multicellular organism growth PMID:22184234 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130304 PRO:LVM PR:000035786 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 5 (Arabidopsis thaliana) At protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 4|At-BRI1/iso:1/Phos:5|UniProtKB:O22476-1, Ser-858/Ser-891, MOD:00046|Thr-872, MOD:00047 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:22184234 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130304 PRO:LVM PR:000035786 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 5 (Arabidopsis thaliana) At protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 4|At-BRI1/iso:1/Phos:5|UniProtKB:O22476-1, Ser-858/Ser-891, MOD:00046|Thr-872, MOD:00047 decreased enables GO:0004672 protein kinase activity PR:000035788 PMID:22184234 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130304 PRO:LVM PR:000035792 BRI1 kinase inhibitor 1 phosphorylated 1 (Arabidopsis thaliana) At-BKI1/Phos:1|AtBKI1 phosphorylated|UniProtKB:Q9FMZ0, Ser-270/Ser-274, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P48348 PMID:22075146 IPI NCBITaxon:3702 UniProtKB:Q9FMZ0 20130305 PRO:LVM PR:000035792 BRI1 kinase inhibitor 1 phosphorylated 1 (Arabidopsis thaliana) At-BKI1/Phos:1|AtBKI1 phosphorylated|UniProtKB:Q9FMZ0, Ser-270/Ser-274, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P48349 PMID:22075146 IPI NCBITaxon:3702 UniProtKB:Q9FMZ0 20130305 PRO:LVM PR:000035792 BRI1 kinase inhibitor 1 phosphorylated 1 (Arabidopsis thaliana) At-BKI1/Phos:1|AtBKI1 phosphorylated|UniProtKB:Q9FMZ0, Ser-270/Ser-274, MOD:00046 located_in GO:0005737 cytoplasm PMID:22075146 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130305 PRO:LVM PR:000035792 BRI1 kinase inhibitor 1 phosphorylated 1 (Arabidopsis thaliana) At-BKI1/Phos:1|AtBKI1 phosphorylated|UniProtKB:Q9FMZ0, Ser-270/Ser-274, MOD:00046 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:22075146 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130305 PRO:LVM PR:000035794 BRI1 kinase inhibitor 1 unphosphorylated form (Arabidopsis thaliana) At-BKI1/PhosRes-|AtBKI1 unphosphorylated form located_in GO:0005886 plasma membrane PMID:21289069|PMID:22075146 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130318 PRO:LVM PR:000035794 BRI1 kinase inhibitor 1 unphosphorylated form (Arabidopsis thaliana) At-BKI1/PhosRes-|AtBKI1 unphosphorylated form acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:22075146 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130305 PRO:CNA PR:000035833 activated IkappaB kinase complex (human) activated IKK complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130412 Reactome:REACT_6894 PR:000035834 nuclear factor NF-kappa-B p50 subunit (human) hNFKBp50|NF-KAPPA-B P50 (human)|NFKB1 p50 (human)|p50 (human)|PRO_0000030311|UniProtKB:P19838-1, 1-433 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 UniProtKB:P18939-1 20130412 Reactome:REACT_6894 PR:000035846 BRI1 kinase inhibitor 1 phosphorylated 2 (Arabidopsis thaliana) At-BKI1/Phos:2|UniProtKB:Q9FMZ0, Tyr-211, MOD:00048 located_in GO:0005829 cytosol PMID:21289069 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130329 PRO:LVM PR:000035846 BRI1 kinase inhibitor 1 phosphorylated 2 (Arabidopsis thaliana) At-BKI1/Phos:2|UniProtKB:Q9FMZ0, Tyr-211, MOD:00048 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:21289069 EXP NCBITaxon:3702 UniProtKB:Q9FMZ0 20130318 PRO:LVM PR:000035857 uric acid degradation bifunctional protein TTL phosphorylated 1 (Arabidopsis thaliana) At-TTL(ALNS)/Phos:1 enables GO:0040015 negative regulation of multicellular organism growth PMID:15319482 EXP NCBITaxon:3702 UniProtKB:Q9LVM5 20130329 PRO:LVM PR:000035857 uric acid degradation bifunctional protein TTL phosphorylated 1 (Arabidopsis thaliana) At-TTL(ALNS)/Phos:1 enables GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:15319482 EXP NCBITaxon:3702 UniProtKB:Q9LVM5 20130329 PRO:LVM PR:000035857 uric acid degradation bifunctional protein TTL phosphorylated 1 (Arabidopsis thaliana) At-TTL(ALNS)/Phos:1 located_in GO:0005886 plasma membrane PMID:15319482 EXP NCBITaxon:3702 UniProtKB:Q9LVM5 20130329 PRO:LVM PR:000035860 transcription factor MYBL2(At1g71030) phosphorylated 1 (Arabidopsis thaliana) At-MYBL2(At1g71030)/Phos:1 enables GO:0005515 protein binding PR:Q9LN63 PMID:23169658 IPI NCBITaxon:3702 UniProtKB:Q9C9A5 20130329 PRO:LVM PR:000035860 transcription factor MYBL2(At1g71030) phosphorylated 1 (Arabidopsis thaliana) At-MYBL2(At1g71030)/Phos:1 acts_upstream_of_or_within GO:0010629 negative regulation of gene expression PMID:23169658 EXP NCBITaxon:3702 UniProtKB:Q9C9A5 20130329 PRO:LVM PR:000035860 transcription factor MYBL2(At1g71030) phosphorylated 1 (Arabidopsis thaliana) At-MYBL2(At1g71030)/Phos:1 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:23169658 EXP NCBITaxon:3702 UniProtKB:Q9C9A5 20130329 PRO:LVM PR:000035886 chorion-specific transcription factor GCMa acetylated 1 (mouse) Gcm1 acetylated 1 (mouse)|mGCM1/Ac:1|UniProtKB:P70348, Lys-367/Lys-406, MOD:00064 acts_upstream_of_or_within GO:0060143 positive regulation of syncytium formation by plasma membrane fusion MGI_ref:5049808|PMID:21558372 IMP NCBITaxon:10090 MGI:108045 20130408 MGI:MGI regulates_o_occurs_in(CL:0000351) PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated located_in GO:0005634 nucleus PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated acts_upstream_of_or_within GO:0009704 de-etiolation PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated acts_upstream_of_or_within GO:0009910 negative regulation of flower development PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated acts_upstream_of_or_within GO:0048366 leaf development PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated acts_upstream_of_or_within GO:0048640 negative regulation of developmental growth PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035889 shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana) At-ASKtheta/Phos:1|atASKtheta phosphorylated acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035891 protein BRASSINAZOLE-RESISTANT 2 phosphorylated 2 (Arabidopsis thaliana) At-BZR2/Phos:2 located_in GO:0005634 nucleus PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q9LN63 20130412 PRO:LVM Evidence=Fig4. PR:000035896 BES1/BZR1 homolog protein 2 phosphorylated 1 (Arabidopsis thaliana) At-BEH2/Phos:1 located_in GO:0005634 nucleus PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q94A43 20130412 PRO:LVM PR:000035898 shaggy-related protein kinase theta unphosphorylated form (Arabidopsis thaliana) At-ASKtheta/PhosRes-|atASKtheta unphosphorylated acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:20128883 EXP NCBITaxon:3702 UniProtKB:Q96287 20130412 PRO:LVM PR:000035954 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/Phos:1|UniProtKB:Q94F62, Ser-290, MOD:00046|Thr-312/Thr-446/Thr-449/Thr-455, MOD:00047 enables GO:0004672 protein kinase activity PMID:18694562 EXP NCBITaxon:3702 UniProtKB:Q94F62 20130412 PRO:LVM PR:000035954 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/Phos:1|UniProtKB:Q94F62, Ser-290, MOD:00046|Thr-312/Thr-446/Thr-449/Thr-455, MOD:00047 acts_upstream_of_or_within GO:0040018 positive regulation of multicellular organism growth PMID:18694562 EXP NCBITaxon:3702 UniProtKB:Q94F62 20130412 PRO:LVM PR:000035954 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 phosphorylated 1 (Arabidopsis thaliana) At-plantBAK1/Phos:1|UniProtKB:Q94F62, Ser-290, MOD:00046|Thr-312/Thr-446/Thr-449/Thr-455, MOD:00047 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:18694562 EXP NCBITaxon:3702 UniProtKB:Q94F62 20130412 PRO:LVM PR:000035956 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 6 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:6|UniProtKB:O22476-1, Ser-1162, MOD:00046|Thr-1180, MOD:00047 acts_upstream_of_or_within GO:0006469 negative regulation of protein kinase activity PMID:15935775 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130412 PRO:LVM PR:000035956 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 6 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:6|UniProtKB:O22476-1, Ser-1162, MOD:00046|Thr-1180, MOD:00047 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:15935775 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130412 PRO:LVM PR:000035956 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 6 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:6|UniProtKB:O22476-1, Ser-1162, MOD:00046|Thr-1180, MOD:00047 decreased enables GO:0004672 protein kinase activity PR:000035788 PMID:15935775 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 enables GO:0009911 positive regulation of flower development PMID:17681130 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P48349 PMID:17681130 IPI NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 located_in GO:0005737 cytoplasm PMID:17681130 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 acts_upstream_of_or_within GO:0048366 leaf development PMID:17681130 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:17681130 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035958 protein BRASSINAZOLE-RESISTANT 1 phosphorylated 3 (Arabidopsis thaliana) At-BZR1/Phos:3|UniProtKB:Q8S307, Ser-173, MOD:00046 decreased enables GO:0003677 DNA binding PR:000035950 PMID:17681130 EXP NCBITaxon:3702 UniProtKB:Q8S307 20130412 PRO:LVM PR:000035961 U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana) At-PUB13/Phos:1 enables GO:0004842 ubiquitin-protein transferase activity PMID:21680842 EXP NCBITaxon:3702 UniProtKB:Q9SNC6 20130412 PRO:LVM Target=PR:Q9FL28. PR:000035961 U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana) At-PUB13/Phos:1 enables GO:0005515 protein binding PR:Q9FL28 PMID:21680842 IPI NCBITaxon:3702 UniProtKB:Q9SNC6 20130412 PRO:LVM PR:000035961 U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana) At-PUB13/Phos:1 enables GO:0005515 protein binding PR:Q9ZV31 PMID:21680842 IPI NCBITaxon:3702 UniProtKB:Q9SNC6 20130412 PRO:LVM PR:000035961 U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana) At-PUB13/Phos:1 part_of GO:0000151 ubiquitin ligase complex PMID:21680842 IDA NCBITaxon:3702 UniProtKB:Q9SNC6 20130412 PRO:LVM PR:000035961 U-box domain-containing protein 13 phosphorylated 1 (Arabidopsis thaliana) At-PUB13/Phos:1 acts_upstream_of_or_within GO:1900425 negative regulation of defense response to bacterium PMID:21680842 EXP NCBITaxon:3702 UniProtKB:Q9SNC6 20130412 PRO:LVM PR:000035966 mitogen-activated protein kinase kinase 4 phosphorylated 1 (Arabidopsis thaliana) At-MKK4/Phos:1|UniProtKB:O80397, Ser-6, MOD:00046|Thr-234, MOD:00047|(Ser-230 or 231, MOD:00046) located_in GO:0005634 nucleus PMID:23341468 EXP NCBITaxon:3702 UniProtKB:O80397 20130412 PRO:LVM Evidence=Fig6. PR:000035966 mitogen-activated protein kinase kinase 4 phosphorylated 1 (Arabidopsis thaliana) At-MKK4/Phos:1|UniProtKB:O80397, Ser-6, MOD:00046|Thr-234, MOD:00047|(Ser-230 or 231, MOD:00046) located_in GO:0005737 cytoplasm PMID:23341468 EXP NCBITaxon:3702 UniProtKB:O80397 20130412 PRO:LVM Evidence=Fig6. PR:000035966 mitogen-activated protein kinase kinase 4 phosphorylated 1 (Arabidopsis thaliana) At-MKK4/Phos:1|UniProtKB:O80397, Ser-6, MOD:00046|Thr-234, MOD:00047|(Ser-230 or 231, MOD:00046) acts_upstream_of_or_within GO:2000037 regulation of stomatal complex patterning PMID:23341468 EXP NCBITaxon:3702 UniProtKB:O80397 20130412 PRO:LVM PR:000035966 mitogen-activated protein kinase kinase 4 phosphorylated 1 (Arabidopsis thaliana) At-MKK4/Phos:1|UniProtKB:O80397, Ser-6, MOD:00046|Thr-234, MOD:00047|(Ser-230 or 231, MOD:00046) decreased enables GO:0004672 protein kinase activity PR:000035968 PMID:23341468 EXP NCBITaxon:3702 UniProtKB:O80397 20130412 PRO:LVM Target=PR:000028877. PR:000035971 shaggy-related protein kinase eta unphosphorylated form (Arabidopsis thaliana) At-ASK7/PhosRes- acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:19734888 EXP NCBITaxon:3702 UniProtKB:Q39011 20130429 PRO:LVM PR:000035974 serine/threonine-protein kinase BSK1 phosphorylated 1 (Arabidopsis thaliana) At-BSK1/Phos:1|UniProtKB:Q944A7, Ser-230, MOD:00046 located_in GO:0009986 cell surface PMID:18653891 EXP NCBITaxon:3702 UniProtKB:Q944A7 20130429 PRO:LVM Note=phosphorylation experiment in vitro. PR:000035974 serine/threonine-protein kinase BSK1 phosphorylated 1 (Arabidopsis thaliana) At-BSK1/Phos:1|UniProtKB:Q944A7, Ser-230, MOD:00046 acts_upstream_of_or_within GO:1900459 positive regulation of brassinosteroid mediated signaling pathway PMID:18653891 EXP NCBITaxon:3702 UniProtKB:Q944A7 20130429 PRO:LVM Note=phosphorylation experiment in vitro. PR:000035976 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 7 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:7|UniProtKB:O22476-1, Tyr-831/Tyr-956/Tyr-1072, MOD:00048|Ser-858/Ser-891, MOD:00046|Thr-872, MOD:00047 enables GO:0004672 protein kinase activity PMID:22891071 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130429 PRO:LVM PR:000035979 U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana) At-PUB12/Phos:1 enables GO:0004842 ubiquitin-protein transferase activity PMID:21680842 EXP NCBITaxon:3702 UniProtKB:Q9ZV31 20130429 PRO:LVM Target=PR:Q9FL28. PR:000035979 U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana) At-PUB12/Phos:1 enables GO:0005515 protein binding PR:Q9FL28 PMID:21680842 IPI NCBITaxon:3702 UniProtKB:Q9ZV31 20130429 PRO:LVM PR:000035979 U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana) At-PUB12/Phos:1 enables GO:0005515 protein binding PR:Q9SNC6 PMID:21680842 IPI NCBITaxon:3702 UniProtKB:Q9ZV31 20130429 PRO:LVM PR:000035979 U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana) At-PUB12/Phos:1 part_of GO:0000151 ubiquitin ligase complex PMID:21680842 EXP NCBITaxon:3702 UniProtKB:Q9ZV31 20130429 PRO:LVM PR:000035979 U-box domain-containing protein 12 phosphorylated 1 (Arabidopsis thaliana) At-PUB12/Phos:1 acts_upstream_of_or_within GO:1900425 negative regulation of defense response to bacterium PMID:21680842 EXP NCBITaxon:3702 UniProtKB:Q9ZV31 20130429 PRO:LVM PR:000035992 peptidyl-prolyl cis-trans isomerase CYP18-3 unphosphorylated form (Arabidopsis thaliana) At-CYP18-3/PhosRes- acts_upstream_of_or_within GO:0009704 de-etiolation PMID:22463079 EXP NCBITaxon:3702 UniProtKB:P34790 20130430 PRO:LVM PR:000035992 peptidyl-prolyl cis-trans isomerase CYP18-3 unphosphorylated form (Arabidopsis thaliana) At-CYP18-3/PhosRes- acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:22463079 EXP NCBITaxon:3702 UniProtKB:P34790 20130430 PRO:LVM PR:000035995 auxin response factor 2 phosphorylated 1 (Arabidopsis thaliana) At-ARF2/Phos:1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:18599455 EXP NCBITaxon:3702 UniProtKB:Q94JM3 20130430 PRO:LVM PR:000035995 auxin response factor 2 phosphorylated 1 (Arabidopsis thaliana) At-ARF2/Phos:1 acts_upstream_of_or_within GO:1900458 negative regulation of brassinosteroid mediated signaling pathway PMID:18599455 EXP NCBITaxon:3702 UniProtKB:Q94JM3 20130430 PRO:LVM PR:000035995 auxin response factor 2 phosphorylated 1 (Arabidopsis thaliana) At-ARF2/Phos:1 decreased enables GO:0003677 DNA binding PR:000035997 PMID:18599455 EXP NCBITaxon:3702 UniProtKB:Q94JM3 20130430 PRO:LVM PR:000035999 protein BRASSINOSTEROID INSENSITIVE 1 isoform 1 phosphorylated 8 (Arabidopsis thaliana) At-BRI1/iso:1/Phos:8|UniProtKB:O22476-1, Ser-838, MOD:00046|Thr-842, MOD:00047|Thr-846, MOD:00047|Ser-858, MOD:00046|Thr-872, MOD:00047|(Ser-887, MOD:00046 or Ser-891, MOD:00046)|(Ser-981, MOD:00046 or Thr-982, MOD:00047)|(Thr-1039, MOD:00047 or Ser-1042, MOD:00046 or Ser-1044, MOD:00046 or Thr-1045, MOD:00047 or Thr-1049, MOD:00047 or Ser-1060, MOD:00046)|(Ser-1166, MOD:00046 or Ser-1168, MOD:00046 or Thr-1169, MOD:00047)|(Ser-1172, MOD:00046 or Ser-1179, MOD:00046 or Thr-1180, MOD:00047 or Ser-1187, MOD:00046) enables GO:0004674 protein serine/threonine kinase activity PMID:11027724 EXP NCBITaxon:3702 UniProtKB:O22476-1 20130430 PRO:LVM PR:000036004 LY96:TLR4 complex (human) h(LY96:TLR4)|MD2:TLR4 complex (human)|TLR4MD2 complex (human) located_in GO:0005886 plasma membrane Reactome:REACT_7105 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036004 LY96:TLR4 complex (human) h(LY96:TLR4)|MD2:TLR4 complex (human)|TLR4MD2 complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036005 LY96:TLR4 complex (mouse) m(LY96:TLR4)|MD2:TLR4 complex (mouse)|TLR4MD2 complex (mouse) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:17803912 EXP NCBITaxon:10090 20140814 PRO:CNA PR:000036007 TIRAP:PIP2 complex (mouse) MAL:PIP2|TIRAPPIP2 acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway PMID:11544529 EXP NCBITaxon:9606 20130430 TLR:AMM PR:000036014 TIRAP:PIP2 complex (human) MAL:PI(4,5)P2|MAL:PIP2 human|TIRAP:PIP2 human located_in GO:0005886 plasma membrane Reactome:REACT_151450 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036014 TIRAP:PIP2 complex (human) MAL:PI(4,5)P2|MAL:PIP2 human|TIRAP:PIP2 human acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25222 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human) TRAF3:TRIF:TRAM:activated TLR4 (human) enables GO:0004842 ubiquitin-protein transferase activity Reactome:REACT_124037 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human) TRAF3:TRIF:TRAM:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_124037 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human) TRAF3:TRIF:TRAM:activated TLR4 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_124037 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human) RIP1:TRIF:activated TLR4 (human)|RIP1:trif:tram:activated TLR4 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_25948 EXP NCBITaxon:9606 20130521 PRO:CNA PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human) RIP1:TRIF:activated TLR4 (human)|RIP1:trif:tram:activated TLR4 complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130521 PRO:CNA PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human) SARM:TRIF:TRAM:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_151758 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human) SARM:TRIF:TRAM:activated TLR4 (human) acts_upstream_of_or_within GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway Reactome:REACT_151758 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF3 (human) enables GO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF7 (human) enables GO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF7 (human) located_in GO:0010008 endosome membrane Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-TBK1:IRF7 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF3 (human) enables GO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF7 (human) enables GO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF7 (human) located_in GO:0010008 endosome membrane Reactome:REACT_27000 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-poly-Ub-TRAF3:p-IKKE:IRF7 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) K63-poly-Ub-TRAF3:TRIF:TRAM:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_124855 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human) K63-poly-Ub-TRAF3:TRIF:TRAM:activated TLR4 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036043 IRF3-P:p65 complex (mouse) located_in GO:0005634 nucleus PMID:14557267 EXP NCBITaxon:10090 20130430 TLR:AMM PR:000036043 IRF3-P:p65 complex (mouse) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:14557267 EXP NCBITaxon:10090 20130430 PRO:CNA PR:000036045 IRF3:XPO1 complex (human) IRF3pIRF3pIMP4alpha human|IRF3pIRF3pQip1 human located_in GO:0005737 cytoplasm PMID:10805757 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-RIP1 (human) located_in GO:0010008 endosome membrane Reactome:REACT_25755 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-RIP1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036051 receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 (human) hRIPK1/K63polyUbiq:1|K-63 polyubiquitinated RIP1 (human)|K63-linked polyUb - RIP1 (human)|K63polyUb-RIP1 (human)|K63polyUb-RIPK1 (human)|UniProtKB:Q13546, Lys-377, PR:000044772 located_in GO:0005737 cytoplasm Reactome:REACT_26236 EXP NCBITaxon:9606 UniProtKB:Q13546 20130430 PRO:CNA PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-RIP1:IKKcomplex (human) located_in GO:0010008 endosome membrane Reactome:REACT_26016 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:K63-pUb-RIP1:IKKcomplex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) RIP3:TRIF:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_152149 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human) RIP3:TRIF:activated TLR4 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) RIP3:RIP1:TRIF:activated TLR4 (human) located_in GO:0010008 endosome membrane Reactome:REACT_151344 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human) RIP3:RIP1:TRIF:activated TLR4 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human) enables GO:0004197 cysteine-type endopeptidase activity Reactome:REACT_151344 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human) located_in GO:0010008 endosome membrane Reactome:REACT_151344 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human) activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036077 activated TLR4 complex (mouse) LY96:LPS:TLR4 complex (mouse)|MD2:LPS:TLR4 complex (mouse)|mTLR4actv|TLR4MD2LPS complex dimer (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:23565187 EXP NCBITaxon:10090 20140718 TLR:AMM PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse) rip1:traf6:trif:tram:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human) activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human) located_in GO:0010008 endosome membrane Reactome:REACT_26959 EXP NCBITaxon:9606 20130515 PRO:CNA PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human) activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130515 PRO:CNA PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human) activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-IKK epsilon (human) located_in GO:0010008 endosome membrane Reactome:REACT_26959 EXP NCBITaxon:9606 20130515 PRO:CNA PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human) activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-IKK epsilon (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130515 PRO:CNA PR:000036135 TIRAP:PIP2:activated TLR4 complex (human) Mal:activated TLR4 complex (human) located_in GO:0005886 plasma membrane Reactome:REACT_152404 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036135 TIRAP:PIP2:activated TLR4 complex (human) Mal:activated TLR4 complex (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25222 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036136 lipopolysaccharide receptor complex 3; plasma membrane (human) h(LPSR:3)pm|TLR4:MD2:LPS:CD14 [plasma membrane] (human) located_in GO:0005886 plasma membrane Reactome:REACT_6894 EXP NCBITaxon:9606 Reactome:REACT_7465 20130430 PRO:CNA PR:000036136 lipopolysaccharide receptor complex 3; plasma membrane (human) h(LPSR:3)pm|TLR4:MD2:LPS:CD14 [plasma membrane] (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 Reactome:REACT_7465 20130430 PRO:CNA PR:000036137 lipopolysaccharide receptor complex 3; endosome membrane (human) h(LPSR:3)endosome|TLR4:MD2:LPS:CD14 [endosome membrane] (human) located_in GO:0010008 endosome membrane Reactome:REACT_6894 EXP NCBITaxon:9606 Reactome:REACT_124771 20140521 PRO:CNA PR:000036137 lipopolysaccharide receptor complex 3; endosome membrane (human) h(LPSR:3)endosome|TLR4:MD2:LPS:CD14 [endosome membrane] (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 EXP NCBITaxon:9606 20130430 PRO:CNA PR:000036149 tbk1:tank:ikke complex (mouse) tbk1tankikke (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:17823124 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000036150 doublesex- and mab-3-related transcription factor 1 homodimer (mouse) Dmrt1 homodimer (mouse) enables GO:0043565 sequence-specific DNA binding PMID:17605809 EXP NCBITaxon:10090 20130528 PRO:KRC PR:000036151 doublesex and mab-3 related transcription factor 2 homodimer (mouse) Dmrt2 homodimer (mouse) enables GO:0043565 sequence-specific DNA binding PMID:17605809 EXP NCBITaxon:10090 20130528 PRO:KRC PR:000036152 doublesex- and mab-3-related transcription factor A1 homodimer (mouse) Dmrta1 homodimer (mouse) enables GO:0043565 sequence-specific DNA binding PMID:17605809 EXP NCBITaxon:10090 20130528 PRO:KRC PR:000036153 doublesex- and mab-3-related transcription factor A2 homodimer (mouse) Dmrta2 homodimer (mouse) enables GO:0043565 sequence-specific DNA binding PMID:17605809 EXP NCBITaxon:10090 20130528 PRO:KRC PR:000036154 doublesex- and mab-3-related transcription factor C2 homodimer (mouse) Dmrtc2 homodimer (mouse) enables GO:0043565 sequence-specific DNA binding PMID:17605809 EXP NCBITaxon:10090 20130528 PRO:KRC PR:000036294 pituitary homeobox 2 isoform 4 (human) hPITX2/iso:4 enables GO:0005515 protein binding PR:Q99697-2 PMID:11948188 IPI NCBITaxon:9606 HGNC:9005 20150223 PRO:CNA Note=Sequence not deposited in any database PR:000036294 pituitary homeobox 2 isoform 4 (human) hPITX2/iso:4 enables GO:0005515 protein binding PR:Q99697-3 PMID:11948188 IPI NCBITaxon:9606 HGNC:9005 20150223 PRO:CNA Note=Sequence not deposited in any database PR:000036294 pituitary homeobox 2 isoform 4 (human) hPITX2/iso:4 acts_upstream_of_or_within GO:0043433 negative regulation of DNA-binding transcription factor activity PMID:11948188 IDA NCBITaxon:9606 HGNC:9005 20080301 PRO:CNA Note=Sequence not deposited in any database PR:000036294 pituitary homeobox 2 isoform 4 (human) hPITX2/iso:4 NOT enables GO:0003677 DNA binding PMID:11948188 IDA NCBITaxon:9606 HGNC:9005 20080301 PRO:CNA Note=Sequence not deposited in any database PR:000036395 interleukin-15 receptor subunit alpha isoform 1 IL15RA/iso:1 located_in GO:0005886 plasma membrane MGI_ref:4461380|PMID:20374432 IDA NCBITaxon:10090 MGI:104644 20130610 MGI:MGI PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse) mIFNG/iso:1/SigPep-/GlycoRes+|PRO_0000016453, MOD:00693|UniProtKB:P01580-1, 23-155, MOD:00693 enables GO:0005125 cytokine activity PMID:11027433|PMID:12925700|PMID:15240719 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA Note=Mature IFGN is heterogeneous in its C-terminus PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse) mIFNG/iso:1/SigPep-/GlycoRes+|PRO_0000016453, MOD:00693|UniProtKB:P01580-1, 23-155, MOD:00693 located_in GO:0005615 extracellular space PMID:11057672|PMID:11728336|PMID:15240714 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA Note=Mature IFGN is heterogeneous in its C-terminus PR:000036407 interferon gamma isoform 1, signal peptide removed glycosylated form (mouse) mIFNG/iso:1/SigPep-/GlycoRes+|PRO_0000016453, MOD:00693|UniProtKB:P01580-1, 23-155, MOD:00693 acts_upstream_of_or_within GO:0050776 regulation of immune response PMID:12882831 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA Note=Mature IFGN is heterogeneous in its C-terminus PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:11483955 TAS NCBITaxon:9606 UniProtKB:P37173-1 20080301 PRO:CNA PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 enables GO:0005515 protein binding PR:000000616 PMID:1310899 IPI NCBITaxon:9606 UniProtKB:P37173-1 20090303 PRO:CNA PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 enables GO:0005515 protein binding PR:000000634 PMID:1850637 IPI NCBITaxon:9606 UniProtKB:P37173-1 20080301 PRO:CNA Note=The binding is shown to the ectodomain. The form is inferred by curator. PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 enables GO:0050431 transforming growth factor beta binding PMID:11850637|PMID:1310899 IC NCBITaxon:9606 PMID:11850637|PMID:1310899 UniProtKB:P37173-1 20080301 PRO:CNA PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 located_in GO:0016020 membrane PMID:1310899 TAS NCBITaxon:9606 UniProtKB:P37173-1 20080301 PRO:CNA PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11483955 TAS NCBITaxon:9606 UniProtKB:P37173-1 20080301 PRO:CNA PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human) hTGFBR2/iso:1/SigPep-|hTGFBR2/iso:RII-1/SigPep-|PRO_0000024426|TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)|UniProtKB:P37173-1, 23-567 acts_upstream_of_or_within GO:0007181 transforming growth factor beta receptor complex assembly PMID:1310899|PMID:8774881 IC NCBITaxon:9606 PMID:1310899|PMID:8774881 UniProtKB:P37173-1 20080301 PRO:CNA PR:000036409 chordin isoform 1, signal peptide removed form (mouse) mCHRD/iso:1/SigPep-|PRO_0000005365|UniProtKB:Q9Z0E2-1, 27-948 enables GO:0005515 protein binding PMID:15381701 IPI NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036409 chordin isoform 1, signal peptide removed form (mouse) mCHRD/iso:1/SigPep-|PRO_0000005365|UniProtKB:Q9Z0E2-1, 27-948 enables GO:0008201 heparin binding PMID:15381701 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036409 chordin isoform 1, signal peptide removed form (mouse) mCHRD/iso:1/SigPep-|PRO_0000005365|UniProtKB:Q9Z0E2-1, 27-948 located_in GO:0005615 extracellular space PMID:15780974 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036409 chordin isoform 1, signal peptide removed form (mouse) mCHRD/iso:1/SigPep-|PRO_0000005365|UniProtKB:Q9Z0E2-1, 27-948 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:11784076 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036409 chordin isoform 1, signal peptide removed form (mouse) mCHRD/iso:1/SigPep-|PRO_0000005365|UniProtKB:Q9Z0E2-1, 27-948 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:10479448|PMID:15780974 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036410 chordin isoform 1, signal peptide removed form (frog) frog-CHRD/iso:1/SigPep-|PRO_0000005367|UniProtKB:Q91713-1, 20-941 located_in GO:0005615 extracellular space PMID:8752213 IDA NCBITaxon:8355 UniProtKB:Q91713-1 20080301 PRO:CNA PR:000036410 chordin isoform 1, signal peptide removed form (frog) frog-CHRD/iso:1/SigPep-|PRO_0000005367|UniProtKB:Q91713-1, 20-941 part_of GO:0032991 protein-containing complex PMID:8752213 IDA NCBITaxon:8355 UniProtKB:Q91713-1 20080301 PRO:CNA PR:000036411 chordin isoform 1 cleaved 2 (mouse) mCHRD/iso:1/Clv:2|UniProtKB:Q9Z0E2-1, 154-861 located_in GO:0005615 extracellular space PMID:10479448 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036411 chordin isoform 1 cleaved 2 (mouse) mCHRD/iso:1/Clv:2|UniProtKB:Q9Z0E2-1, 154-861 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:10479448 IDA NCBITaxon:10090 UniProtKB:Q9Z0E2-1 20080301 PRO:CNA PR:000036412 follistatin isoform 1, signal peptide removed glycosylated form (human) hFST/iso:1/SigPep-/GlycoRes+|PRO_0000010103, MOD:00693|UniProtKB:P19883-1, 30-344, MOD:00693 located_in GO:0005615 extracellular space PMID:16150905 IDA NCBITaxon:9606 UniProtKB:P19883-1 20080301 PRO:CNA PR:000036413 follistatin isoform 1 cleaved and N-glycosylated 2 (pig) pig-FST/iso:1/ClvNGlyco:2|PRO_0000419163, Asn-124/Asn-288, MOD:00160|UniProtKB:P10669-1, 30-332, Asn-124/Asn-288, MOD:00160 acts_upstream_of_or_within GO:0032926 negative regulation of activin receptor signaling pathway PMID:8340384 IDA NCBITaxon:9823 UniProtKB:P10669-1 20080301 PRO:CNA PR:000036414 follistatin isoform 1 cleaved and N-glycosylated 2 (human) hFST/iso:1/ClvNGlyco:2|UniProtKB:P19883-1, 30-332, Asn-124/Asn-288, MOD:00160 located_in GO:0005615 extracellular space PMID:16150905 IDA NCBITaxon:9606 UniProtKB:P19883-1 20080301 PRO:CNA PR:000036415 follistatin isoform 2, signal peptide removed N-glycosylated 1 (human) hFST/iso:2/SigPep-/NGlyco:1|UniProtKB:P19883-2, 30-317, Asn-124/Asn-288, MOD:00160 located_in GO:0005615 extracellular space PMID:16150905 IDA NCBITaxon:9606 UniProtKB:P19883-2 20080301 PRO:CNA PR:000036415 follistatin isoform 2, signal peptide removed N-glycosylated 1 (human) hFST/iso:2/SigPep-/NGlyco:1|UniProtKB:P19883-2, 30-317, Asn-124/Asn-288, MOD:00160 acts_upstream_of_or_within GO:0032926 negative regulation of activin receptor signaling pathway PMID:1906804 IDA NCBITaxon:9606 UniProtKB:P19883-2 20080301 PRO:CNA PR:000036417 growth/differentiation factor 5 sequence variant V186* (mouse) bp-3J (mouse)|mGDF5/var:V186*|UniProtKB:P43027, 1-185 associated_with_disease_progression MP:0006279 abnormal limb development PMID:8145850 EXP NCBITaxon:10090 UniProtKB:P43027-1 20080301 PRO:CNA PR:000036417 growth/differentiation factor 5 sequence variant V186* (mouse) bp-3J (mouse)|mGDF5/var:V186*|UniProtKB:P43027, 1-185 has_agent SO:0001587 stop_gained PMID:8145850 EXP NCBITaxon:10090 UniProtKB:P43027-1 20080301 PRO:CNA PR:000036418 interferon gamma isoform 1, signal peptide removed form (mouse) mIFNG/iso:1/SigPep-|PRO_0000016453|UniProtKB:P01580-1, 23-155 enables GO:0005125 cytokine activity PMID:11441112 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA Note=Recombinant mature protein not glycosylated PR:000036418 interferon gamma isoform 1, signal peptide removed form (mouse) mIFNG/iso:1/SigPep-|PRO_0000016453|UniProtKB:P01580-1, 23-155 acts_upstream_of_or_within GO:0050776 regulation of immune response PMID:11441112 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA PR:000036419 interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human) hIFNG/iso:1/SigPep-/NGlyco:1|UniProtKB:P01579-1, 24-157, Asn-48/Asn-120, MOD:00160 enables GO:0005133 type II interferon receptor binding PMID:10986460 IDA NCBITaxon:9606 UniProtKB:P01579-1 20080301 PRO:CNA Note=Glycosylation sites by similarity but shown to be glycoprotein [PMIDs:10823661, 2434486] PR:000036419 interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human) hIFNG/iso:1/SigPep-/NGlyco:1|UniProtKB:P01579-1, 24-157, Asn-48/Asn-120, MOD:00160 enables GO:0042803 protein homodimerization activity PMID:3109913 IDA NCBITaxon:9606 UniProtKB:P01579-1 20080301 PRO:CNA Note=Glycosylation sites by similarity but shown to be glycoprotein [PMIDs:10823661, 2434486] PR:000036419 interferon gamma isoform 1, signal peptide removed N-glycosylated 1 (human) hIFNG/iso:1/SigPep-/NGlyco:1|UniProtKB:P01579-1, 24-157, Asn-48/Asn-120, MOD:00160 located_in GO:0005615 extracellular space PMID:6427223 IDA NCBITaxon:9606 UniProtKB:P01579-1 20080301 PRO:CNA Note=Glycosylation sites by similarity but shown to be glycoprotein [PMIDs:10823661, 2434486] PR:000036420 interferon gamma isoform 1 cleaved and N-glycosylated 2 (human) hIFNG/iso:1/ClvNGlyco:2|PRO_0000016444, Asn-48/Asn-120, MOD:00160|UniProtKB:P01579-1, 24-161, Asn-48/Asn-120, MOD:00160 enables GO:0042803 protein homodimerization activity PMID:1902591 IDA NCBITaxon:9606 UniProtKB:P01579-1 20080301 PRO:CNA PR:000036421 noggin isoform 1, signal peptide removed form (human) hNOG/iso:1/SigPep-|PRO_0000019813|UniProtKB:Q13253-1, 28-232 enables GO:0005515 protein binding PR:000036517 PMID:12478285 IPI NCBITaxon:9606 UniProtKB:Q13253-1 20080301 PRO:CNA PR:000036421 noggin isoform 1, signal peptide removed form (human) hNOG/iso:1/SigPep-|PRO_0000019813|UniProtKB:Q13253-1, 28-232 located_in GO:0005615 extracellular space PMID:11562478 IDA NCBITaxon:9606 UniProtKB:Q13253-1 20080301 PRO:CNA PR:000036421 noggin isoform 1, signal peptide removed form (human) hNOG/iso:1/SigPep-|PRO_0000019813|UniProtKB:Q13253-1, 28-232 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:12478285 IDA NCBITaxon:9606 UniProtKB:Q13253-1 20080301 PRO:CNA PR:000036422 BMP receptor type-1A isoform 1 phosphorylated 1 (human) hBMPR1A/iso:1/Phos:1 enables GO:0004674 protein serine/threonine kinase activity PMID:12829744 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:000036422 BMP receptor type-1A isoform 1 phosphorylated 1 (human) hBMPR1A/iso:1/Phos:1 located_in GO:0009986 cell surface PMID:10712517 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:000036422 BMP receptor type-1A isoform 1 phosphorylated 1 (human) hBMPR1A/iso:1/Phos:1 part_of GO:0043235 receptor complex PMID:12829744|PMID:15940369 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:000036422 BMP receptor type-1A isoform 1 phosphorylated 1 (human) hBMPR1A/iso:1/Phos:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:12065756 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:000036422 BMP receptor type-1A isoform 1 phosphorylated 1 (human) hBMPR1A/iso:1/Phos:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:12829744 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:000036423 BMP receptor type-1A isoform 1 phosphorylated 1 (mouse) mBMPR1A/iso:1/Phos:1 enables GO:0046332 SMAD binding PMID:10814522|PMID:9738003 IDA NCBITaxon:10090 UniProtKB:P36895-1 20080301 PRO:CNA PR:000036425 BMP receptor type-1B isoform 1 phosphorylated 1 (mouse) mBMPR1B/iso:1/Phos:1 located_in GO:0009986 cell surface PMID:10712517|PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:000036425 BMP receptor type-1B isoform 1 phosphorylated 1 (mouse) mBMPR1B/iso:1/Phos:1 part_of GO:0043235 receptor complex PMID:10712517 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:000036425 BMP receptor type-1B isoform 1 phosphorylated 1 (mouse) mBMPR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:000036425 BMP receptor type-1B isoform 1 phosphorylated 1 (mouse) mBMPR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0001502 cartilage condensation PMID:10631181|PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:000036425 BMP receptor type-1B isoform 1 phosphorylated 1 (mouse) mBMPR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0035108 limb morphogenesis PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:000036426 BMP receptor type-1B isoform 1 phosphorylated 1 (human) hBMPR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:10051328 IDA NCBITaxon:9606 UniProtKB:O00238-1 20080301 PRO:CNA PR:000036426 BMP receptor type-1B isoform 1 phosphorylated 1 (human) hBMPR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0045597 positive regulation of cell differentiation PMID:14523231 IDA NCBITaxon:9606 UniProtKB:O00238-1 20080301 PRO:CNA PR:000036427 DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (human) hID2/iso:1/Phos:1|UniProtKB:Q02363-1, Ser-5, MOD:00046 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:9029153 IDA NCBITaxon:9606 UniProtKB:Q02363-1 20080301 PRO:CNA PR:000036428 DNA-binding protein inhibitor ID-2 isoform 1 phosphorylated 1 (rat) rID2/iso:1/Phos:1|UniProtKB:P41137-1, Ser-5, MOD:00046 located_in GO:0005634 nucleus PMID:11706002 IDA NCBITaxon:10116 UniProtKB:P41137-1 20080301 PRO:CNA PR:000036429 DNA-binding protein inhibitor ID-3 isoform 1 phosphorylated 1 (human) hID3/iso:1/Phos:1|UniProtKB:Q02535-1, Ser-5, MOD:00046 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:9372912 IDA NCBITaxon:9606 UniProtKB:Q02535-1 20080301 PRO:CNA PR:000036430 DNA-binding protein inhibitor ID-3 isoform 1 ubiquitinated 1 (mouse) mID3/iso:1/Ubiq:1 located_in GO:0005737 cytoplasm PMID:15451666 IDA NCBITaxon:10090 UniProtKB:P41133-1 20080301 PRO:CNA PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human) hRNF7/iso:1/Phos:1|UniProtKB:Q9UBF6-1, Thr-10, MOD:00047 located_in GO:0005634 nucleus PMID:12748192 IDA NCBITaxon:9606 UniProtKB:Q9UBF6-1 20080301 PRO:CNA PR:000036431 RING-box protein 2 isoform 1 phosphorylated 1 (human) hRNF7/iso:1/Phos:1|UniProtKB:Q9UBF6-1, Thr-10, MOD:00047 located_in GO:0005737 cytoplasm PMID:12748192 IDA NCBITaxon:9606 UniProtKB:Q9UBF6-1 20080301 PRO:CNA PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human) hTGFBR1/iso:1/SigPep-|UniProtKB:P36897-1, 25-503 located_in GO:0005886 plasma membrane PMID:8242743 TAS NCBITaxon:9606 UniProtKB:P36897-1 20080301 PRO:CNA PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human) hTGFBR1/iso:1/SigPep-|UniProtKB:P36897-1, 25-503 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8242743 TAS NCBITaxon:9606 UniProtKB:P36897-1 20080301 PRO:CNA PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human) hTGFBR1/iso:1/SigPep-|UniProtKB:P36897-1, 25-503 acts_upstream_of_or_within GO:0007181 transforming growth factor beta receptor complex assembly PMID:8242743 TAS NCBITaxon:9606 UniProtKB:P36897-1 20080301 PRO:CNA PR:000036434 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse) mTGFBR1/iso:1/SigPep-/Phos:1|UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:12065756 IDA NCBITaxon:10090 UniProtKB:Q64729-1 20090309 PRO:CNA PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hACVR1/iso:1/SigPep-/Phos:1 enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8389764 IDA NCBITaxon:9606 UniProtKB:Q04771-1 20080301 PRO:CNA PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hACVR1/iso:1/SigPep-/Phos:1 enables GO:0048185 activin binding PMID:8242742 IDA NCBITaxon:9606 UniProtKB:Q04771-1 20080301 PRO:CNA PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hACVR1/iso:1/SigPep-/Phos:1 located_in GO:0005886 plasma membrane PMID:8242742|PMID:8397373 IDA NCBITaxon:9606 UniProtKB:Q04771-1 20080301 PRO:CNA PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hACVR1/iso:1/SigPep-/Phos:1 part_of GO:0048179 activin receptor complex PMID:8242742 IDA NCBITaxon:9606 UniProtKB:Q04771-1 20080301 PRO:CNA PR:000036435 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) hACVR1/iso:1/SigPep-/Phos:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:8242742|PMID:8389764 IDA NCBITaxon:9606 UniProtKB:Q04771-1 20080301 PRO:CNA PR:000036436 activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse) mACVR1/iso:1/SigPep-/Phos:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:11376112 IDA NCBITaxon:10090 UniProtKB:P37172-1 20080301 PRO:CNA PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human) hACVR1B/iso:1/Phos:1 enables GO:0016361 activin receptor activity, type I PMID:8622651 IDA NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human) hACVR1B/iso:1/Phos:1 enables GO:0046332 SMAD binding PR:000000066 PMID:12065756 IPI NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human) hACVR1B/iso:1/Phos:1 located_in GO:0005886 plasma membrane PMID:8397373 IDA NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human) hACVR1B/iso:1/Phos:1 located_in GO:0009986 cell surface PMID:12665502 IDA NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human) hACVR1B/iso:1/Phos:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:12065756 IDA NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:000036439 activin receptor type-1C isoform 1 phosphorylated 1 (human) hACVR1C/iso:1/Phos:1 enables GO:0016361 activin receptor activity, type I PMID:12063393|PMID:15196700 IDA NCBITaxon:9606 UniProtKB:Q8NER5-1 20080301 PRO:CNA PR:000036439 activin receptor type-1C isoform 1 phosphorylated 1 (human) hACVR1C/iso:1/Phos:1 located_in GO:0005886 plasma membrane PMID:12606401 IDA NCBITaxon:9606 UniProtKB:Q8NER5-1 20080301 PRO:CNA PR:000036439 activin receptor type-1C isoform 1 phosphorylated 1 (human) hACVR1C/iso:1/Phos:1 part_of GO:0048179 activin receptor complex PMID:15531507 IDA NCBITaxon:9606 UniProtKB:Q8NER5-1 20080301 PRO:CNA PR:000036439 activin receptor type-1C isoform 1 phosphorylated 1 (human) hACVR1C/iso:1/Phos:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:12065756 IDA NCBITaxon:9606 UniProtKB:Q8NER5-1 20080301 PRO:CNA PR:000036439 activin receptor type-1C isoform 1 phosphorylated 1 (human) hACVR1C/iso:1/Phos:1 acts_upstream_of_or_within GO:0042981 regulation of apoptotic process PMID:15531507 IDA NCBITaxon:9606 UniProtKB:Q8NER5-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8395525 EXP NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 enables GO:0016362 activin receptor activity, type II PMID:8395525 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 enables GO:0019838 growth factor binding PMID:11459935|PMID:12414726 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 enables GO:0042803 protein homodimerization activity PMID:8612709 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 part_of GO:0048179 activin receptor complex PMID:8395525 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 acts_upstream_of_or_within GO:0008584 male gonad development PMID:7885474 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036440 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (mouse) mACVR2A/iso:1/GlycoPhos:1 acts_upstream_of_or_within GO:0009952 anterior/posterior pattern specification PMID:10452853|PMID:16991118 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:000036441 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human) hACVR2A/iso:1/GlycoPhos:1 enables GO:0016362 activin receptor activity, type II PMID:12665502 IDA NCBITaxon:9606 UniProtKB:P27037-1 20080301 PRO:CNA PR:000036441 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human) hACVR2A/iso:1/GlycoPhos:1 located_in GO:0005886 plasma membrane PMID:1314589 IDA NCBITaxon:9606 UniProtKB:P27037-1 20080301 PRO:CNA PR:000036441 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human) hACVR2A/iso:1/GlycoPhos:1 part_of GO:0048179 activin receptor complex PMID:8622651 IDA NCBITaxon:9606 UniProtKB:P27037-1 20080301 PRO:CNA PR:000036441 activin receptor type-2A isoform 1 glycosylated and phosphorylated 1 (human) hACVR2A/iso:1/GlycoPhos:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:1314589 IDA NCBITaxon:9606 UniProtKB:P27037-1 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:1326537 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 enables GO:0019838 growth factor binding PMID:11459935|PMID:12414726 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:8721982 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 acts_upstream_of_or_within GO:0009952 anterior/posterior pattern specification PMID:10452853|PMID:16991118 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 acts_upstream_of_or_within GO:0032925 regulation of activin receptor signaling pathway PMID:8721982 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036442 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (mouse) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (mouse)|mACVR2B/iso:1/GlycoPhos:1|mACVR2B/iso:ActR-IIB2/NGlycoPhos:1 NOT enables GO:0050431 transforming growth factor beta binding PMID:1326537 IDA NCBITaxon:10090 UniProtKB:P27040-2 20080301 PRO:CNA PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)|hACVR2B/iso:1/GlycoPhos:1|hACVR2B/iso:ActR-IIB2/NGlycoPhos:1 enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8622651 IDA NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)|hACVR2B/iso:1/GlycoPhos:1|hACVR2B/iso:ActR-IIB2/NGlycoPhos:1 enables GO:0005515 protein binding PR:Q9UNH7 PMID:11279102|PMID:9872992 IPI NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)|hACVR2B/iso:1/GlycoPhos:1|hACVR2B/iso:ActR-IIB2/NGlycoPhos:1 enables GO:0016362 activin receptor activity, type II PMID:8622651 IDA NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)|hACVR2B/iso:1/GlycoPhos:1|hACVR2B/iso:ActR-IIB2/NGlycoPhos:1 located_in GO:0005886 plasma membrane PMID:8161782 IDA NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:000036443 activin receptor type-2B isoform ActR-IIB2 N-glycosylated and phosphorylated 1 (human) activin receptor type-2B isoform 1 glycosylated and phosphorylated 1 (human)|hACVR2B/iso:1/GlycoPhos:1|hACVR2B/iso:ActR-IIB2/NGlycoPhos:1 part_of GO:0048179 activin receptor complex PMID:8622651 IDA NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 enables GO:0005102 signaling receptor binding PMID:14750901 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 enables GO:0005179 hormone activity PMID:14750901 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 enables GO:0046983 protein dimerization activity PMID:14673134 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 located_in GO:0005576 extracellular region PMID:14750901|PMID:3754790 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 acts_upstream_of_or_within GO:0001880 Mullerian duct regression PMID:14750901|PMID:3754790 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:3754790 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036444 Muellerian-inhibiting factor isoform 1 cleaved and N-glycosylated 2 (human) hAMH/iso:1/ClvNGlyco:2|UniProtKB:P03971-1, 26-450, 451-560, MOD:00160 acts_upstream_of_or_within GO:0007548 sex differentiation PMID:12834017 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036448 c-myc protein isoform 1 phosphorylated 1 (human) hMYC/iso:1/Phos:1|UniProtKB:P01106-1, Ser-62, MOD:00046 enables GO:0005515 protein binding PR:O15169-1 PMID:19131971 IPI NCBITaxon:9606 UniProtKB:P01106-1 20101020 PRO:CNA PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human) hCOMP/iso:1/SigPep-|PRO_0000035857|UniProtKB:P49747-1, 21-757 enables GO:0005201 extracellular matrix structural constituent PMID:9749943 IDA NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human) hCOMP/iso:1/SigPep-|PRO_0000035857|UniProtKB:P49747-1, 21-757 enables GO:0005509 calcium ion binding PMID:7670472 TAS NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human) hCOMP/iso:1/SigPep-|PRO_0000035857|UniProtKB:P49747-1, 21-757 located_in GO:0031012 extracellular matrix PMID:9749943 IDA NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human) hCOMP/iso:1/SigPep-|PRO_0000035857|UniProtKB:P49747-1, 21-757 acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:7713493 TAS NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:000036453 CREB-binding protein isoform 1 methylated 1 (mouse) mCREBBP/iso:1/Me:1|UniProtKB:P45481-1, Arg-600/Arg-624, MOD:00658 located_in GO:0005634 nucleus PMID:11701890 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:000036453 CREB-binding protein isoform 1 methylated 1 (mouse) mCREBBP/iso:1/Me:1|UniProtKB:P45481-1, Arg-600/Arg-624, MOD:00658 NOT part_of GO:0000123 histone acetyltransferase complex PMID:11701890 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:000036454 cullin-1 isoform 1 neddylated 1 (human) hCUL1/iso:1/Nedd:1|UniProtKB:Q13616-1, Lys-720, MOD:01150 part_of GO:0019005 SCF ubiquitin ligase complex PMID:10713156|PMID:10921923|PMID:17098746 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:000036454 cullin-1 isoform 1 neddylated 1 (human) hCUL1/iso:1/Nedd:1|UniProtKB:Q13616-1, Lys-720, MOD:01150 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:8681378 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:000036454 cullin-1 isoform 1 neddylated 1 (human) hCUL1/iso:1/Nedd:1|UniProtKB:Q13616-1, Lys-720, MOD:01150 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:8681378 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:000036454 cullin-1 isoform 1 neddylated 1 (human) hCUL1/iso:1/Nedd:1|UniProtKB:Q13616-1, Lys-720, MOD:01150 acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PMID:10713156|PMID:10921923 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:000036454 cullin-1 isoform 1 neddylated 1 (human) hCUL1/iso:1/Nedd:1|UniProtKB:Q13616-1, Lys-720, MOD:01150 acts_upstream_of_or_within GO:0097193 intrinsic apoptotic signaling pathway PMID:8681378 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:000036456 decorin isoform A, mature form (human) hDCN/iso:A/mature|PRO_0000032710|UniProtKB:P07585-1, 31-359 enables GO:0005154 epidermal growth factor receptor binding PMID:9988678 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036456 decorin isoform A, mature form (human) hDCN/iso:A/mature|PRO_0000032710|UniProtKB:P07585-1, 31-359 located_in GO:0031012 extracellular matrix PMID:17651433 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036456 decorin isoform A, mature form (human) hDCN/iso:A/mature|PRO_0000032710|UniProtKB:P07585-1, 31-359 acts_upstream_of_or_within GO:0030199 collagen fibril organization PMID:17651433 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036457 decorin isoform A cleaved and glycosylated 1 (human) hDCN/iso:A/ClvGlyco:1|PRO_0000032710, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160|UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160 enables GO:0005154 epidermal growth factor receptor binding PMID:9988678 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036457 decorin isoform A cleaved and glycosylated 1 (human) hDCN/iso:A/ClvGlyco:1|PRO_0000032710, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160|UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160 located_in GO:0031012 extracellular matrix PMID:17651433|PMID:9988678 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036457 decorin isoform A cleaved and glycosylated 1 (human) hDCN/iso:A/ClvGlyco:1|PRO_0000032710, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160|UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160 acts_upstream_of_or_within GO:0030199 collagen fibril organization PMID:17651433 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036458 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human) hFASLG/iso:FasL/NGlyco:1|UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160 enables GO:0005102 signaling receptor binding PMID:9405425 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036458 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human) hFASLG/iso:FasL/NGlyco:1|UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160 acts_upstream_of_or_within GO:0097190 apoptotic signaling pathway PMID:9405425 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human) hFASLG/iso:FasL/Clv:soluble|PRO_0000034501|UniProtKB:P48023-1, 130-281 enables GO:0005102 signaling receptor binding PMID:9405425 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human) hFASLG/iso:FasL/Clv:soluble|PRO_0000034501|UniProtKB:P48023-1, 130-281 enables GO:0042802 identical protein binding PMID:7536672|PMID:9228058|PMID:9405425 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human) hFASLG/iso:FasL/Clv:soluble|PRO_0000034501|UniProtKB:P48023-1, 130-281 located_in GO:0005615 extracellular space PMID:7536672 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human) hFASLG/iso:FasL/Clv:soluble|PRO_0000034501|UniProtKB:P48023-1, 130-281 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:9396774 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:000036460 decorin isoform A cleaved 2 (human) hDCN/iso:A/Clv:2|UniProtKB:P07585-1, ?-170 located_in GO:0031012 extracellular matrix PMID:12621051 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:000036461 latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (human) hLTBP1/iso:2/SigPep-|UniProtKB:Q14766-2, 21-1395 enables GO:0005515 protein binding PR:000000617 PMID:10930463 IPI NCBITaxon:9606 UniProtKB:Q14766-2 20080301 PRO:CNA PR:000036461 latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (human) hLTBP1/iso:2/SigPep-|UniProtKB:Q14766-2, 21-1395 part_of GO:0032991 protein-containing complex PMID:10930463|PMID:11104663 IDA NCBITaxon:9606 PR:000000618|UniProtKB:P01137-1 UniProtKB:Q14766-2 20080301 PRO:CNA PR:000036462 latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (mouse) mLTBP1/iso:2/SigPep-|UniProtKB:Q8CG19-2, 20-1394 located_in GO:0005615 extracellular space PMID:9008713 IDA NCBITaxon:10090 UniProtKB:Q8CG19-2 20080301 PRO:CNA PR:000036462 latent TGF-beta-binding protein 1 isoform 2, signal peptide removed form (mouse) mLTBP1/iso:2/SigPep-|UniProtKB:Q8CG19-2, 20-1394 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11104663|PMID:7730318 IDA NCBITaxon:10090 UniProtKB:Q8CG19-2 20080301 PRO:CNA PR:000036463 latent TGF-beta-binding protein 1 isoform 1, signal peptide removed form (human) hLTBP1/iso:1/SigPep-|UniProtKB:Q14766-1, 24-1595 enables GO:0005024 transforming growth factor beta receptor activity PMID:8537398 IDA NCBITaxon:9606 UniProtKB:Q14766-1 20080301 PRO:CNA PR:000036463 latent TGF-beta-binding protein 1 isoform 1, signal peptide removed form (human) hLTBP1/iso:1/SigPep-|UniProtKB:Q14766-1, 24-1595 located_in GO:0031012 extracellular matrix PMID:8537398 IDA NCBITaxon:9606 UniProtKB:Q14766-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 enables GO:0004672 protein kinase activity PMID:14744933 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 enables GO:0004707 MAP kinase activity PMID:11684667|PMID:12223545|PMID:15314156|PMID:8626447 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 located_in GO:0005634 nucleus PMID:11726647|PMID:12925581|PMID:16251435 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 acts_upstream_of_or_within GO:0000165 MAPK cascade PMID:8626447 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:15284227 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse) mMAPK1/iso:1/Phos:1|UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 acts_upstream_of_or_within GO:0007165 signal transduction PMID:11684667 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:000036466 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (rat) rMAPK1/iso:1/Phos:1|UniProtKB:P63086-1, Thr-183, MOD:00047|Tyr-185, MOD:00048 enables GO:0042803 protein homodimerization activity PMID:9604935 IDA NCBITaxon:10116 UniProtKB:P63086-1 20080301 PRO:CNA PR:000036468 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (mouse) mMAPK3/iso:1/Phos:1|UniProtKB:Q63844-1, Thr-203, MOD:00047|Tyr-205, MOD:00048 enables GO:0004672 protein kinase activity PMID:11684667|PMID:15314156 IDA NCBITaxon:10090 UniProtKB:Q63844-1 20080301 PRO:CNA PR:000036468 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (mouse) mMAPK3/iso:1/Phos:1|UniProtKB:Q63844-1, Thr-203, MOD:00047|Tyr-205, MOD:00048 enables GO:0004707 MAP kinase activity PMID:15314156 IDA NCBITaxon:10090 UniProtKB:Q63844-1 20080301 PRO:CNA PR:000036468 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (mouse) mMAPK3/iso:1/Phos:1|UniProtKB:Q63844-1, Thr-203, MOD:00047|Tyr-205, MOD:00048 located_in GO:0005634 nucleus PMID:11726647 IDA NCBITaxon:10090 UniProtKB:Q63844-1 20080301 PRO:CNA PR:000036468 mitogen-activated protein kinase 3 isoform 1 phosphorylated 1 (mouse) mMAPK3/iso:1/Phos:1|UniProtKB:Q63844-1, Thr-203, MOD:00047|Tyr-205, MOD:00048 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:11841548|PMID:15383658 IDA NCBITaxon:10090 UniProtKB:Q63844-1 20080301 PRO:CNA PR:000036469 nodal protein isoform 1, signal peptide removed form (mouse) mNODAL/iso:1/SigPep-|UniProtKB:P43021-1, ?-354 enables GO:0042803 protein homodimerization activity PMID:15649361 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA Note=Sequence coordinates of mature not determined PR:000036469 nodal protein isoform 1, signal peptide removed form (mouse) mNODAL/iso:1/SigPep-|UniProtKB:P43021-1, ?-354 located_in GO:0005615 extracellular space PMID:15649361 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA Note=Sequence coordinates of mature not determined PR:000036469 nodal protein isoform 1, signal peptide removed form (mouse) mNODAL/iso:1/SigPep-|UniProtKB:P43021-1, ?-354 acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:12654299 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA Note=Sequence coordinates of mature not determined PR:000036469 nodal protein isoform 1, signal peptide removed form (mouse) mNODAL/iso:1/SigPep-|UniProtKB:P43021-1, ?-354 acts_upstream_of_or_within GO:0009952 anterior/posterior pattern specification PMID:15004567 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA Note=Sequence coordinates of mature not determined PR:000036470 retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human) hRBL1/iso:1/Phos:1|UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046 enables GO:0005515 protein binding PMID:11884610 IPI NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:000036470 retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human) hRBL1/iso:1/Phos:1|UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:11884610 IDA NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:000036470 retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human) hRBL1/iso:1/Phos:1|UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046 NOT enables GO:0030308 negative regulation of cell growth PMID:11884610 IDA NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:000036471 retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human) hRBL2/iso:1/Phos:1|UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:11042701|PMID:11157749|PMID:8710362 IDA NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036471 retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human) hRBL2/iso:1/Phos:1|UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046 NOT enables GO:0005515 protein binding PMID:11157749 IPI NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036471 retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human) hRBL2/iso:1/Phos:1|UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046 NOT enables GO:0030308 negative regulation of cell growth PMID:11157749 IDA NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036472 retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human) hRBL2/iso:1/Phos:2|UniProtKB:Q08999-1, Ser-672, MOD:00046 enables GO:0005515 protein binding PR:Q13309 PMID:12006580 IPI NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036472 retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human) hRBL2/iso:1/Phos:2|UniProtKB:Q08999-1, Ser-672, MOD:00046 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:12006580 IDA NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036472 retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human) hRBL2/iso:1/Phos:2|UniProtKB:Q08999-1, Ser-672, MOD:00046 NOT enables GO:0030308 negative regulation of cell growth PMID:12006580 IDA NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA Note=hyperphosphorylated by CdKs, phosphorylated residue important for proteasome targeting Ser-672. PR:000036473 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human) hRBL2/iso:1/Phos:3|UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047 enables GO:0005515 protein binding PR:Q16254 PMID:11042701|PMID:11157749 IPI NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036473 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human) hRBL2/iso:1/Phos:3|UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:11042701|PMID:11157749|PMID:8710362 IDA NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:000036474 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse) mRBL2/iso:1/Phos:3 part_of GO:0005667 transcription factor complex PMID:10082561 IDA NCBITaxon:10090 UniProtKB:Q64700-1 20080301 PRO:CNA PR:000036476 Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse) mROCK1/iso:1/Clv:1|UniProtKB:P70335-1, 1-1113 acts_upstream_of_or_within GO:0010659 cardiac muscle cell apoptotic process PMID:16983089 EXP NCBITaxon:10090 UniProtKB:P70335-1 20090401 PRO:CNA PR:000036476 Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse) mROCK1/iso:1/Clv:1|UniProtKB:P70335-1, 1-1113 acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:11283607|PMID:16983089 IDA NCBITaxon:10090 UniProtKB:P70335-1 20080301 PRO:CNA PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human) hROCK2/iso:1/Clv:1|UniProtKB:O75116-1, 1-1131 located_in GO:0005622 intracellular anatomical structure PMID:15699075 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human) hROCK2/iso:1/Clv:1|UniProtKB:O75116-1, 1-1131 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:15699075 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human) hROCK2/iso:1/Clv:1|UniProtKB:O75116-1, 1-1131 acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:15699075 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human) hROCK2/iso:1/Clv:1|UniProtKB:O75116-1, 1-1131 increased enables GO:0004674 protein serine/threonine kinase activity PR:000002530 PMID:15699075 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036478 Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human) hROCK2/iso:1/Phos:1|UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046 enables GO:0004674 protein serine/threonine kinase activity PMID:17446864 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036478 Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human) hROCK2/iso:1/Phos:1|UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046 located_in GO:0005634 nucleus PMID:15302935 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036478 Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human) hROCK2/iso:1/Phos:1|UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:17446864 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036479 Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human) hROCK2/iso:1/Phos:2|UniProtKB:O75116-1, Thr-1078, MOD:00047 acts_upstream_of_or_within GO:0042770 signal transduction in response to DNA damage PMID:17525332 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:000036480 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human) hRPS6KB1/iso:1/Phos:1|UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047 enables GO:0004672 protein kinase activity PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-1 20080301 PRO:CNA PR:000036480 ribosomal protein S6 kinase beta-1 isoform 1 phosphorylated 1 (human) hRPS6KB1/iso:1/Phos:1|UniProtKB:P23443-1, Ser-441/Ser-447, MOD:00046|Thr-444, MOD:00047 acts_upstream_of_or_within GO:0007165 signal transduction PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-1 20080301 PRO:CNA PR:000036481 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human) hRPS6KB1/iso:2/Phos:1 enables GO:0004672 protein kinase activity PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-2 20080301 PRO:CNA PR:000036481 ribosomal protein S6 kinase beta-1 isoform 2 phosphorylated 1 (human) hRPS6KB1/iso:2/Phos:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-2 20080301 PRO:CNA PR:000036483 mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human) hSMAD4/iso:1/Phos:1|UniProtKB:Q13485-1, Thr-277, MOD:00047 located_in GO:0005634 nucleus PMID:12801888 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:000036483 mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human) hSMAD4/iso:1/Phos:1|UniProtKB:Q13485-1, Thr-277, MOD:00047 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12801888 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:000036483 mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human) hSMAD4/iso:1/Phos:1|UniProtKB:Q13485-1, Thr-277, MOD:00047 increased enables GO:0003700 DNA-binding transcription factor activity PR:000002539 PMID:12801888 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:000036485 thrombospondin-1 isoform 1, signal peptide removed form (mouse) mTHBS1/iso:1/SigPep-|PRO_0000035843|UniProtKB:P35441-1, 19-1170 located_in GO:0005615 extracellular space PMID:12498716 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036486 thrombospondin-1 isoform 1 cleaved 2 (mouse) mTHBS1/iso:1/Clv:2|UniProtKB:P35441-1, 19-311 enables GO:0042802 identical protein binding PR:000036486 PMID:17082774 IPI NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036486 thrombospondin-1 isoform 1 cleaved 2 (mouse) mTHBS1/iso:1/Clv:2|UniProtKB:P35441-1, 19-311 acts_upstream_of_or_within GO:0016525 negative regulation of angiogenesis PMID:17082774 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036486 thrombospondin-1 isoform 1 cleaved 2 (mouse) mTHBS1/iso:1/Clv:2|UniProtKB:P35441-1, 19-311 acts_upstream_of_or_within GO:0060055 angiogenesis involved in wound healing PMID:17082774 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse) mTHBS1/iso:1/SigPep-/GlycoRes+|PRO_0000035843, MOD:00222|MOD:00812|MOD:00813|UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813 enables GO:0005515 protein binding PR:000036486 PMID:1459996 IPI NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse) mTHBS1/iso:1/SigPep-/GlycoRes+|PRO_0000035843, MOD:00222|MOD:00812|MOD:00813|UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813 enables GO:0050431 transforming growth factor beta binding PMID:9657149 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse) mTHBS1/iso:1/SigPep-/GlycoRes+|PRO_0000035843, MOD:00222|MOD:00812|MOD:00813|UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813 located_in GO:0005615 extracellular space PMID:9657149 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human) hTHBS1/iso:1/SigPep-/Glyco:1|PRO_0000035842, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813|UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813 enables GO:0005515 protein binding PR:000028966 PMID:3305519 IPI NCBITaxon:9606 UniProtKB:P07996-1 20080301 PRO:CNA PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human) hTHBS1/iso:1/SigPep-/Glyco:1|PRO_0000035842, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813|UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813 enables GO:0050431 transforming growth factor beta binding PMID:15342643 IDA NCBITaxon:9606 UniProtKB:P07996-1 20080301 PRO:CNA PR:000036490 thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse) mTHBS1/iso:1/Clv:2/GlycoRes+|UniProtKB:P35441-1, 312-1170, MOD:00693 acts_upstream_of_or_within GO:0016525 negative regulation of angiogenesis PMID:17082774 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036490 thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse) mTHBS1/iso:1/Clv:2/GlycoRes+|UniProtKB:P35441-1, 312-1170, MOD:00693 acts_upstream_of_or_within GO:0060055 angiogenesis involved in wound healing PMID:17082774 IDA NCBITaxon:10090 UniProtKB:P35441-1 20080301 PRO:CNA PR:000036491 thrombospondin-2 isoform 1, signal peptide removed form (human) hTHBS2/iso:1/SigPep-|PRO_0000035846|UniProtKB:P35442-1, 19-1172 enables GO:0008201 heparin binding PMID:1459996 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000036494 thrombospondin-3 isoform 1, signal peptide removed form (mouse) mTHBS3/iso:1/SigPep-|PRO_0000035850|UniProtKB:Q05895-1, 22-956 enables GO:0005509 calcium ion binding PMID:8288588 IDA NCBITaxon:10090 UniProtKB:Q05895-1 20080301 PRO:CNA PR:000036494 thrombospondin-3 isoform 1, signal peptide removed form (mouse) mTHBS3/iso:1/SigPep-|PRO_0000035850|UniProtKB:Q05895-1, 22-956 enables GO:0008201 heparin binding PMID:8288588 IDA NCBITaxon:10090 UniProtKB:Q05895-1 20080301 PRO:CNA PR:000036494 thrombospondin-3 isoform 1, signal peptide removed form (mouse) mTHBS3/iso:1/SigPep-|PRO_0000035850|UniProtKB:Q05895-1, 22-956 enables GO:0042802 identical protein binding PR:000036494 PMID:7759526 IPI NCBITaxon:10090 UniProtKB:Q05895-1 20080301 PRO:CNA PR:000036494 thrombospondin-3 isoform 1, signal peptide removed form (mouse) mTHBS3/iso:1/SigPep-|PRO_0000035850|UniProtKB:Q05895-1, 22-956 located_in GO:0005615 extracellular space PMID:8288588 IDA NCBITaxon:10090 UniProtKB:Q05895-1 20080301 PRO:CNA PR:000036494 thrombospondin-3 isoform 1, signal peptide removed form (mouse) mTHBS3/iso:1/SigPep-|PRO_0000035850|UniProtKB:Q05895-1, 22-956 acts_upstream_of_or_within GO:0007160 cell-matrix adhesion PMID:8468055 IDA NCBITaxon:10090 UniProtKB:Q05895-1 20080301 PRO:CNA PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human) hSP1/iso:1/Ac:1 enables GO:0003677 DNA binding PMID:15647279 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human) hSP1/iso:1/Ac:1 located_in GO:0005634 nucleus PMID:15647279 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036496 transcription factor Sp1 isoform 1 acetylated 1 (human) hSP1/iso:1/Ac:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15647279 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human) hSP1/iso:1/Clv:1|UniProtKB:P08047-1, 65-785 enables GO:0003700 DNA-binding transcription factor activity PMID:16407261 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036497 transcription factor Sp1 isoform 1 cleaved 1 (human) hSP1/iso:1/Clv:1|UniProtKB:P08047-1, 65-785 located_in GO:0005634 nucleus PMID:16407261 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human) hSP1/iso:1/OGlyco:1|UniProtKB:P08047-1, Ser-491, MOD:00805 enables GO:0003677 DNA binding PMID:11371615 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human) hSP1/iso:1/OGlyco:1|UniProtKB:P08047-1, Ser-491, MOD:00805 located_in GO:0005634 nucleus PMID:11371615 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036498 transcription factor Sp1 isoform 1 O-glycosylated 1 (human) hSP1/iso:1/OGlyco:1|UniProtKB:P08047-1, Ser-491, MOD:00805 increased enables GO:0003700 DNA-binding transcription factor activity PR:000036497 PMID:11371615 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036499 transcription factor Sp1 isoform 1 phosphorylated 1 (human) hSP1/iso:1/Phos:1 enables GO:0003677 DNA binding PMID:2170018 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036499 transcription factor Sp1 isoform 1 phosphorylated 1 (human) hSP1/iso:1/Phos:1 located_in GO:0005634 nucleus PMID:2170018|PMID:9525578 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036500 transcription factor Sp1 isoform 1 phosphorylated 2 (human) hSP1/iso:1/Phos:2|UniProtKB:P08047-1, Thr-579, MOD:00047 located_in GO:0005634 nucleus PMID:9153193 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036500 transcription factor Sp1 isoform 1 phosphorylated 2 (human) hSP1/iso:1/Phos:2|UniProtKB:P08047-1, Thr-579, MOD:00047 decreased enables GO:0003700 DNA-binding transcription factor activity PR:000036497 PMID:9153193 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036501 transcription factor Sp1 isoform 1 phosphorylated 3 (human) hSP1/iso:1/Phos:3|UniProtKB:P08047-1, Ser-59, MOD:00046 located_in GO:0005634 nucleus PMID:17049555|PMID:18239466 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036501 transcription factor Sp1 isoform 1 phosphorylated 3 (human) hSP1/iso:1/Phos:3|UniProtKB:P08047-1, Ser-59, MOD:00046 increased enables GO:0003700 DNA-binding transcription factor activity PR:000036497 PMID:17049555|PMID:18239466 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036502 transcription factor Sp1 isoform 1 phosphorylated 4 (human) hSP1/iso:1/Phos:4 located_in GO:0005634 nucleus PMID:18171990 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036502 transcription factor Sp1 isoform 1 phosphorylated 4 (human) hSP1/iso:1/Phos:4 acts_upstream_of_or_within GO:0042770 signal transduction in response to DNA damage PMID:18171990 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036503 transcription factor Sp1 isoform 1 sumoylated 1 (human) hSP1/iso:1/Sumo:1|UniProtKB:P08047-1, Lys-16, MOD:01149 decreased enables GO:0003700 DNA-binding transcription factor activity PR:000036497 PMID:16407261 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human) hTNF/iso:1/Clv:1|PRO_0000034424|UniProtKB:P01375-1, 77-233 enables GO:0005164 tumor necrosis factor receptor binding PR:P19438 PMID:14512626 IPI NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human) hTNF/iso:1/Clv:1|PRO_0000034424|UniProtKB:P01375-1, 77-233 enables GO:0042802 identical protein binding PR:000036504 PMID:14512626 IPI NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human) hTNF/iso:1/Clv:1|PRO_0000034424|UniProtKB:P01375-1, 77-233 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:3856324 IDA NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse) mTNF/iso:1/Clv:1|PRO_0000034436|UniProtKB:P06804-1, 80-235 located_in GO:0005615 extracellular space PMID:10089307 IDA NCBITaxon:10090 UniProtKB:P06804-1 20080301 PRO:CNA PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse) mTNF/iso:1/Clv:1|PRO_0000034436|UniProtKB:P06804-1, 80-235 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:9305915 IDA NCBITaxon:10090 UniProtKB:P06804-1 20080301 PRO:CNA PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse) mTNF/iso:1/Clv:2|UniProtKB:P06804-1, 70-235 located_in GO:0005576 extracellular region PMID:2777790 IDA NCBITaxon:10090 UniProtKB:P06804-1 20150820 PRO:CNA PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse) mTNF/iso:1/Clv:2|UniProtKB:P06804-1, 70-235 NOT enables GO:0005125 cytokine activity PMID:2777790 IDA NCBITaxon:10090 UniProtKB:P06804-1 20080301 PRO:CNA PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human) hTNF/iso:1/Myr:1|UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087 located_in GO:0016020 membrane PMID:1402651 IDA NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:000036508 tumor necrosis factor isoform 1 phosphorylated 1 (human) hTNF/iso:1/Phos:1|UniProtKB:P01375-1, Ser-2, MOD:00046 located_in GO:0016020 membrane PMID:10205166 IDA NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse) mBMP2/iso:1/mature|PRO_0000033827|UniProtKB:P21274-1, 281-394 located_in GO:0005615 extracellular space PMID:15110716 IDA NCBITaxon:10090 UniProtKB:P21274-1 20080301 PRO:CNA PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse) mBMP2/iso:1/mature|PRO_0000033827|UniProtKB:P21274-1, 281-394 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:15565649|PMID:16109715 IDA NCBITaxon:10090 UniProtKB:P21274-1 20080301 PRO:CNA PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse) mBMP2/iso:1/mature|PRO_0000033827|UniProtKB:P21274-1, 281-394 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P21274-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 enables GO:0005102 signaling receptor binding PMID:11401399|PMID:14660436 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 enables GO:0042803 protein homodimerization activity PMID:12805376 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 located_in GO:0005615 extracellular space PMID:12805376 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 acts_upstream_of_or_within GO:0001649 osteoblast differentiation PMID:14749725 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 acts_upstream_of_or_within GO:0001657 ureteric bud development PMID:12141440 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 acts_upstream_of_or_within GO:0001934 positive regulation of protein phosphorylation PMID:14749725 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 acts_upstream_of_or_within GO:0007498 mesoderm development PMID:9804553 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human) hBMP4/iso:1/mature|PRO_0000033857|UniProtKB:P12644-1, 293-408 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:12805376 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:000036512 bone morphogenetic protein 4 isoform 1, mature form (mouse) mBMP4/iso:1/mature|PRO_0000033859|UniProtKB:P21275-1, 293-408 acts_upstream_of_or_within GO:0001649 osteoblast differentiation PMID:15381701 IDA NCBITaxon:10090 UniProtKB:P21275-1 20080301 PRO:CNA PR:000036512 bone morphogenetic protein 4 isoform 1, mature form (mouse) mBMP4/iso:1/mature|PRO_0000033859|UniProtKB:P21275-1, 293-408 acts_upstream_of_or_within GO:0001657 ureteric bud development PMID:12631064 IDA NCBITaxon:10090 UniProtKB:P21275-1 20080301 PRO:CNA PR:000036512 bone morphogenetic protein 4 isoform 1, mature form (mouse) mBMP4/iso:1/mature|PRO_0000033859|UniProtKB:P21275-1, 293-408 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P21275-1 20080301 PRO:CNA PR:000036513 bone morphogenetic protein 5 isoform 1, mature form (human) hBMP5/iso:1/mature|UniProtKB:P22003-1, 323-454 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:11401399|PMID:14660436 IDA NCBITaxon:9606 UniProtKB:P22003-1 20080301 PRO:CNA PR:000036514 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human) hBMP6/iso:1/ClvNGlyco:1|PRO_0000033871, Asn-454, MOD:00160|UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160 enables GO:0042803 protein homodimerization activity PMID:15969083|PMID:18070108 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA Note=The active protein region comes from crystal structure. PR:000036514 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human) hBMP6/iso:1/ClvNGlyco:1|PRO_0000033871, Asn-454, MOD:00160|UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:12702725 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:000036514 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human) hBMP6/iso:1/ClvNGlyco:1|PRO_0000033871, Asn-454, MOD:00160|UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160 acts_upstream_of_or_within GO:0001934 positive regulation of protein phosphorylation PMID:16527843 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:000036514 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human) hBMP6/iso:1/ClvNGlyco:1|PRO_0000033871, Asn-454, MOD:00160|UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:15969083 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:000036514 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human) hBMP6/iso:1/ClvNGlyco:1|PRO_0000033871, Asn-454, MOD:00160|UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160 acts_upstream_of_or_within GO:0032349 positive regulation of aldosterone biosynthetic process PMID:16527843 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:000036515 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse) mBMP6/iso:1/ClvNGlyco:1|PRO_0000033873, Asn-451, MOD:00160|UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160 located_in GO:0005615 extracellular space PMID:8089189 IDA NCBITaxon:10090 UniProtKB:P20722-1 20080301 PRO:CNA PR:000036515 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse) mBMP6/iso:1/ClvNGlyco:1|PRO_0000033873, Asn-451, MOD:00160|UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:8089189 IDA NCBITaxon:10090 UniProtKB:P20722-1 20080301 PRO:CNA PR:000036515 bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse) mBMP6/iso:1/ClvNGlyco:1|PRO_0000033873, Asn-451, MOD:00160|UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P20722-1 20080301 PRO:CNA PR:000036516 bone morphogenetic protein 7 isoform 1, mature form (mouse) mBMP7/iso:1/mature|PRO_0000033879|UniProtKB:P23359-1, 292-430 enables GO:0005515 protein binding PMID:12741987 IPI NCBITaxon:10090 UniProtKB:P23359-1 20080301 PRO:CNA PR:000036516 bone morphogenetic protein 7 isoform 1, mature form (mouse) mBMP7/iso:1/mature|PRO_0000033879|UniProtKB:P23359-1, 292-430 located_in GO:0005615 extracellular space PMID:12741987 IDA NCBITaxon:10090 UniProtKB:P23359-1 20080301 PRO:CNA PR:000036516 bone morphogenetic protein 7 isoform 1, mature form (mouse) mBMP7/iso:1/mature|PRO_0000033879|UniProtKB:P23359-1, 292-430 acts_upstream_of_or_within GO:0007411 axon guidance PMID:12741987 IDA NCBITaxon:10090 UniProtKB:P23359-1 20080301 PRO:CNA Note=When bound to PR:000000641 PR:000036517 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human) hBMP7/iso:1/mature/NGlyco:1|PRO_0000033877, Asn-372, MOD:00160|UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160 enables GO:0005102 signaling receptor binding PMID:9872992 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:000036517 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human) hBMP7/iso:1/mature/NGlyco:1|PRO_0000033877, Asn-372, MOD:00160|UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160 enables GO:0042803 protein homodimerization activity PMID:15929982|PMID:8570652 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:000036517 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human) hBMP7/iso:1/mature/NGlyco:1|PRO_0000033877, Asn-372, MOD:00160|UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160 located_in GO:0005615 extracellular space PMID:15047707|PMID:15929982 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:000036518 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse) mBMP7/iso:1/mature/NGlyco:1|PRO_0000033879, Asn-371, MOD:00160|UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P23359-1 20080301 PRO:CNA PR:000036519 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human) hBMP7/iso:1/mature/NGlyco:2|UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160 located_in GO:0005615 extracellular space PMID:15929982 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:000036519 bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human) hBMP7/iso:1/mature/NGlyco:2|UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160 NOT enables GO:0005102 signaling receptor binding PMID:15929982 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:000036520 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human) hRHOA/iso:1/IpCysEst:1|PRO_0000030411, Cys-190, MOD:01119|UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119 located_in GO:0005886 plasma membrane PMID:16773203 IDA NCBITaxon:9606 UniProtKB:P61586-1 20080301 PRO:CNA PR:000036520 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human) hRHOA/iso:1/IpCysEst:1|PRO_0000030411, Cys-190, MOD:01119|UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119 acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:16773203 IDA NCBITaxon:9606 UniProtKB:P61586-1 20080301 PRO:CNA PR:000036520 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human) hRHOA/iso:1/IpCysEst:1|PRO_0000030411, Cys-190, MOD:01119|UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119 acts_upstream_of_or_within GO:0043123 positive regulation of canonical NF-kappaB signal transduction PMID:12761501 IDA NCBITaxon:9606 UniProtKB:P61586-1 20080301 PRO:CNA PR:000036520 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (human) hRHOA/iso:1/IpCysEst:1|PRO_0000030411, Cys-190, MOD:01119|UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119 acts_upstream_of_or_within GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction PMID:12761501 IDA NCBITaxon:9606 UniProtKB:P61586-1 20080301 PRO:CNA PR:000036521 GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester 1 (cow) cow-RHOA/iso:1/IpCysEst:1|PRO_0000030407, Cys-190, MOD:01119|UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119 located_in GO:0005886 plasma membrane PMID:1903193 IDA NCBITaxon:9913 UniProtKB:P61585-1 20080301 PRO:CNA PR:000036526 TGF-beta 1 isoform 1 latency associated peptide (human) hTGFB1/iso:1/LAP|UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160 part_of GO:0032991 protein-containing complex PMID:17015622|PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:000036527 TGF-beta 1 isoform 1 inactive form (green monkey) GrMonkey-TGFB1/iso:1/inactive|PRO_0000033760, PRO_0000033761, Asn-82, MOD:00160|UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160 part_of GO:0032991 protein-containing complex PMID:1448117|PMID:2677679 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000036527 TGF-beta 1 isoform 1 inactive form (green monkey) GrMonkey-TGFB1/iso:1/inactive|PRO_0000033760, PRO_0000033761, Asn-82, MOD:00160|UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:1448117|PMID:2677679 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000036527 TGF-beta 1 isoform 1 inactive form (green monkey) GrMonkey-TGFB1/iso:1/inactive|PRO_0000033760, PRO_0000033761, Asn-82, MOD:00160|UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160 NOT enables GO:0005160 transforming growth factor beta receptor binding PMID:1448117 IDA NCBITaxon:9534 UniProtKB:P09533-1 20080301 PRO:CNA PR:000036529 TGF-beta 1 isoform 1 inactive form (mouse) mTGFB1/iso:1/inactive|PRO_0000033766, PRO_0000033767, Asn-82, MOD:00160|UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160 located_in GO:0031012 extracellular matrix PMID:9008713 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:000036529 TGF-beta 1 isoform 1 inactive form (mouse) mTGFB1/iso:1/inactive|PRO_0000033766, PRO_0000033767, Asn-82, MOD:00160|UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 enables GO:0001540 amyloid-beta binding PMID:16227582 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 enables GO:0005160 transforming growth factor beta receptor binding PMID:16227582 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 enables GO:0042803 protein homodimerization activity PMID:2119582|PMID:3476488 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 located_in GO:0005615 extracellular space PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036530 TGF-beta 2 isoform A cleaved 1 (human) hTGFB2/iso:A/Clv:1|PRO_0000033785|UniProtKB:P61812-1, 303-414 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15944186 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036531 TGF-beta 2 isoform A cleaved 2 (mouse) mTGFB2/iso:A/Clv:2|UniProtKB:P27090-1, 20-302 enables GO:0005515 protein binding PR:Q07475 PMID:14985127 IPI NCBITaxon:10090 UniProtKB:P27090-1 20080301 PRO:CNA PR:000036532 TGF-beta 2 isoform A cleaved 2 (human) hTGFB2/iso:A/Clv:2|UniProtKB:P61812-1, 20-302 part_of GO:0032991 protein-containing complex PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036533 TGF-beta 2 isoform A cleaved 3 (human) hTGFB2/iso:A/Clv:3|UniProtKB:P61812-1, 20-302, 303-414 enables GO:0042803 protein homodimerization activity PMID:3476488 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036533 TGF-beta 2 isoform A cleaved 3 (human) hTGFB2/iso:A/Clv:3|UniProtKB:P61812-1, 20-302, 303-414 located_in GO:0005615 extracellular space PMID:3162913 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:000036534 TGF-beta 2 isoform B cleaved 1 (human) hTGFB2/iso:B/Clv:1|UniProtKB:P61812-2, 331-442 located_in GO:0005615 extracellular space PMID:1777240 IDA NCBITaxon:9606 UniProtKB:P61812-2 20080301 PRO:CNA PR:000036535 TGF-beta 2 isoform B cleaved 2 (human) hTGFB2/iso:B/Clv:2|UniProtKB:P61812-2, 20-330, 331-442 located_in GO:0005615 extracellular space PMID:1777240 IDA NCBITaxon:9606 UniProtKB:P61812-2 20080301 PRO:CNA PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human) hTGFB3/iso:1/Clv:1|PRO_0000033797|UniProtKB:P10600-1, 301-412 enables GO:0005160 transforming growth factor beta receptor binding PMID:18243111 IDA NCBITaxon:9606 UniProtKB:P10600-1 20080301 PRO:CNA PR:000036536 TGF-beta 3 isoform 1 cleaved 1 (human) hTGFB3/iso:1/Clv:1|PRO_0000033797|UniProtKB:P10600-1, 301-412 enables GO:0042803 protein homodimerization activity PMID:18243111 IDA NCBITaxon:9606 UniProtKB:P10600-1 20080301 PRO:CNA PR:000036537 TGF-beta 3 isoform 1 cleaved 1 (mouse) mTGFB3/iso:1/Clv:1|PRO_0000033799|UniProtKB:P17125-1, 299-410 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 EXP NCBITaxon:10090 UniProtKB:P17125-1 20080301 PRO:CNA PR:000036538 TGF-beta 3 isoform 1 cleaved 3 (mouse) mTGFB3/iso:1/Clv:3|UniProtKB:P17125-1, 30-298, 299-410 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 IDA NCBITaxon:10090 UniProtKB:P17125-1 20080301 PRO:CNA PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse) mINHBA/iso:1/Clv:1|PRO_0000033711|UniProtKB:Q04998-1, 309-424 enables GO:0046983 protein dimerization activity PMID:2133547 IDA NCBITaxon:10090 UniProtKB:Q04998-1 20080301 PRO:CNA PR:000036539 activin/inhibin beta A chain isoform 1 cleaved 1 (mouse) mINHBA/iso:1/Clv:1|PRO_0000033711|UniProtKB:Q04998-1, 309-424 contributes_to enables GO:0005102 signaling receptor binding PMID:1646080|PMID:7577669 IDA NCBITaxon:10090 UniProtKB:Q04998-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 enables GO:0046983 protein dimerization activity PMID:1537316 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 located_in GO:0005576 extracellular region PMID:12213882|PMID:2575216 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 part_of GO:0032991 protein-containing complex PMID:12960042 IDA NCBITaxon:9606 PR:000036540 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 part_of GO:0043509 activin A complex PMID:7890768 IDA NCBITaxon:9606 UniProtKB:P08476-1 20090203 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 part_of GO:0043512 inhibin A complex PR:000036608 PMID:17456790|PMID:7890768 IPI NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 acts_upstream_of_or_within GO:0007166 cell surface receptor signaling pathway PMID:12456957 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:12456957 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 acts_upstream_of_or_within GO:0009605 response to external stimulus PMID:10320815 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 acts_upstream_of_or_within GO:0030154 cell differentiation PMID:12456957 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 acts_upstream_of_or_within GO:0032925 regulation of activin receptor signaling pathway PMID:9884026 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036540 activin/inhibin beta A chain isoform 1 cleaved 1 (human) hINHBA/iso:1/Clv:1|PRO_0000033709|UniProtKB:P08476-1, 311-426 contributes_to enables GO:0005102 signaling receptor binding PMID:7890768 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 enables GO:0005515 protein binding PMID:2575216 IPI NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 enables GO:0046983 protein dimerization activity PMID:2575216 IDA NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 located_in GO:0005576 extracellular region PMID:3122219 IDA NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 acts_upstream_of_or_within GO:0030154 cell differentiation PMID:10320815 IDA NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 acts_upstream_of_or_within GO:0046880 regulation of follicle-stimulating hormone secretion PMID:3122219 IDA NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036541 activin/inhibin beta B chain isoform 1 cleaved 1 (human) hINHBB/iso:1/Clv:1|PRO_0000033723|UniProtKB:P09529-1, 293-407 contributes_to enables GO:0005102 signaling receptor binding PMID:3754442 IDA NCBITaxon:9606 UniProtKB:P09529-1 20080301 PRO:CNA PR:000036542 activin/inhibin beta E chain isoform 1 cleaved 1 (mouse) mINHBE/iso:1/Clv:1|PRO_0000033739|UniProtKB:O08717-1, 237-350 enables GO:0046983 protein dimerization activity PMID:15863943 IDA NCBITaxon:10090 UniProtKB:O08717-1 20080301 PRO:CNA PR:000036542 activin/inhibin beta E chain isoform 1 cleaved 1 (mouse) mINHBE/iso:1/Clv:1|PRO_0000033739|UniProtKB:O08717-1, 237-350 located_in GO:0005576 extracellular region PMID:15863943 IDA NCBITaxon:10090 UniProtKB:O08717-1 20080301 PRO:CNA PR:000036542 activin/inhibin beta E chain isoform 1 cleaved 1 (mouse) mINHBE/iso:1/Clv:1|PRO_0000033739|UniProtKB:O08717-1, 237-350 part_of GO:0048180 activin complex PMID:15863943 IDA NCBITaxon:10090 UniProtKB:O08717-1 20080301 PRO:CNA PR:000036542 activin/inhibin beta E chain isoform 1 cleaved 1 (mouse) mINHBE/iso:1/Clv:1|PRO_0000033739|UniProtKB:O08717-1, 237-350 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process PMID:15863943 IDA NCBITaxon:10090 UniProtKB:O08717-1 20080301 PRO:CNA PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human) hGDF5/iso:1/Clv:1|PRO_0000033913|UniProtKB:P43026-1, 382-501 enables GO:0005102 signaling receptor binding PMID:15752764|PMID:15890363 IDA NCBITaxon:9606 UniProtKB:P43026-1 20080301 PRO:CNA PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human) hGDF5/iso:1/Clv:1|PRO_0000033913|UniProtKB:P43026-1, 382-501 enables GO:0005515 protein binding PR:P12643 PMID:9288098 IPI NCBITaxon:9606 UniProtKB:P43026-1 20090630 PRO:CNA PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human) hGDF5/iso:1/Clv:1|PRO_0000033913|UniProtKB:P43026-1, 382-501 enables GO:0008083 growth factor activity PMID:8589725 IDA NCBITaxon:9606 UniProtKB:P43026-1 20090630 PRO:CNA PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human) hGDF5/iso:1/Clv:1|PRO_0000033913|UniProtKB:P43026-1, 382-501 enables GO:0042803 protein homodimerization activity PMID:15752764|PMID:8962721 IDA NCBITaxon:9606 UniProtKB:P43026-1 20090630 PRO:CNA PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human) hGDF5/iso:1/Clv:1|PRO_0000033913|UniProtKB:P43026-1, 382-501 located_in GO:0005615 extracellular space PMID:16532400 IDA NCBITaxon:9606 UniProtKB:P43026-1 20090630 PRO:CNA PR:000036544 growth/differentiation factor 7 isoform 1 cleaved 1 (mouse) mGDF7/iso:1/Clv:1|PRO_0000033925|UniProtKB:P43029-1, 316-461 enables GO:0005515 protein binding PR:000036516 PMID:12741987 IPI NCBITaxon:10090 UniProtKB:P43029-1 20080301 PRO:CNA PR:000036544 growth/differentiation factor 7 isoform 1 cleaved 1 (mouse) mGDF7/iso:1/Clv:1|PRO_0000033925|UniProtKB:P43029-1, 316-461 located_in GO:0005576 extracellular region PMID:12741987 IDA NCBITaxon:10090 UniProtKB:P43029-1 20080301 PRO:CNA PR:000036544 growth/differentiation factor 7 isoform 1 cleaved 1 (mouse) mGDF7/iso:1/Clv:1|PRO_0000033925|UniProtKB:P43029-1, 316-461 acts_upstream_of_or_within GO:0007411 axon guidance PMID:12741987 IDA NCBITaxon:10090 UniProtKB:P43029-1 20080301 PRO:CNA Note=When bound to PR:000000612 PR:000036545 inhibin beta C chain isoform 1 cleaved 1 (human) hINHBC/iso:1/Clv:1|PRO_0000033731|UniProtKB:P55103-1, 237-352 enables GO:0046983 protein dimerization activity PMID:11134153 IDA NCBITaxon:9606 UniProtKB:P55103-1 20080301 PRO:CNA PR:000036545 inhibin beta C chain isoform 1 cleaved 1 (human) hINHBC/iso:1/Clv:1|PRO_0000033731|UniProtKB:P55103-1, 237-352 located_in GO:0005576 extracellular region PMID:16627954|PMID:7826378 IDA NCBITaxon:9606 UniProtKB:P55103-1 20080301 PRO:CNA PR:000036545 inhibin beta C chain isoform 1 cleaved 1 (human) hINHBC/iso:1/Clv:1|PRO_0000033731|UniProtKB:P55103-1, 237-352 part_of GO:0032991 protein-containing complex PMID:11134153|PMID:12960042 IDA NCBITaxon:9606 PR:000036497 UniProtKB:P55103-1 20080301 PRO:CNA PR:000036545 inhibin beta C chain isoform 1 cleaved 1 (human) hINHBC/iso:1/Clv:1|PRO_0000033731|UniProtKB:P55103-1, 237-352 acts_upstream_of_or_within GO:0032926 negative regulation of activin receptor signaling pathway PMID:12960042|PMID:16627954 IDA NCBITaxon:9606 UniProtKB:P55103-1 20080301 PRO:CNA PR:000036545 inhibin beta C chain isoform 1 cleaved 1 (human) hINHBC/iso:1/Clv:1|PRO_0000033731|UniProtKB:P55103-1, 237-352 contributes_to enables GO:0005160 transforming growth factor beta receptor binding PMID:7826378 IDA NCBITaxon:9606 UniProtKB:P55103-1 20080301 PRO:CNA PR:000036546 lefty 1 isoform 1 cleaved 1 (human) hLEFTY1/iso:1/Clv:1|PRO_0000033811|UniProtKB:O75610-1, 77-366 located_in GO:0005615 extracellular space PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O75610-1 20080301 PRO:CNA PR:000036547 lefty 1 isoform 1 cleaved 1 (mouse) mLEFTY1/iso:1/Clv:1|PRO_0000033809|UniProtKB:Q64280-1, 77-368 located_in GO:0005615 extracellular space PMID:18039650 IDA NCBITaxon:10090 UniProtKB:Q64280-1 20080301 PRO:CNA PR:000036547 lefty 1 isoform 1 cleaved 1 (mouse) mLEFTY1/iso:1/Clv:1|PRO_0000033809|UniProtKB:Q64280-1, 77-368 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15004567 IDA NCBITaxon:10090 UniProtKB:Q64280-1 20080301 PRO:CNA PR:000036547 lefty 1 isoform 1 cleaved 1 (mouse) mLEFTY1/iso:1/Clv:1|PRO_0000033809|UniProtKB:Q64280-1, 77-368 acts_upstream_of_or_within GO:0009948 anterior/posterior axis specification PMID:15004567 IDA NCBITaxon:10090 UniProtKB:Q64280-1 20080301 PRO:CNA PR:000036548 lefty 1 isoform 1 cleaved 2 (human) hLEFTY1/iso:1/Clv:2|UniProtKB:O75610-1, 135-366 located_in GO:0005615 extracellular space PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O75610-1 20080301 PRO:CNA PR:000036548 lefty 1 isoform 1 cleaved 2 (human) hLEFTY1/iso:1/Clv:2|UniProtKB:O75610-1, 135-366 acts_upstream_of_or_within GO:0043406 positive regulation of MAP kinase activity PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O75610-1 20080301 PRO:CNA PR:000036549 lefty 2 isoform 1 cleaved 1 (human) hLEFTY2/iso:1/Clv:1|PRO_0000033807|UniProtKB:O00292-1, 77-366 located_in GO:0005615 extracellular space PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:000036549 lefty 2 isoform 1 cleaved 1 (human) hLEFTY2/iso:1/Clv:1|PRO_0000033807|UniProtKB:O00292-1, 77-366 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:10053005 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:000036549 lefty 2 isoform 1 cleaved 1 (human) hLEFTY2/iso:1/Clv:1|PRO_0000033807|UniProtKB:O00292-1, 77-366 acts_upstream_of_or_within GO:0007309 oocyte axis specification PMID:10053005 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:000036550 lefty 2 isoform 1 cleaved 2 (human) hLEFTY2/iso:1/Clv:2|UniProtKB:O00292-1, 135-366 located_in GO:0005615 extracellular space PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:000036550 lefty 2 isoform 1 cleaved 2 (human) hLEFTY2/iso:1/Clv:2|UniProtKB:O00292-1, 135-366 acts_upstream_of_or_within GO:0043406 positive regulation of MAP kinase activity PMID:11278322 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:000036553 smad1 isoform 1 phosphorylated and ubiquitinated 1 (human) hSMAD1/iso:1/PhosUbiq:1|UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046|MOD:01148 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:12857866 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:000036554 smad2 isoform Long acetylated and phosphorylated 1 (human) hSMAD2/iso:Long/AcPhos:1|UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046 located_in GO:0005634 nucleus PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000036554 smad2 isoform Long acetylated and phosphorylated 1 (human) hSMAD2/iso:Long/AcPhos:1|UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000036554 smad2 isoform Long acetylated and phosphorylated 1 (human) hSMAD2/iso:Long/AcPhos:1|UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0007165 signal transduction PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20080301 PRO:CNA PR:000036555 smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse) mSMAD2/iso:Long/PhosUbiq:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148 acts_upstream_of_or_within GO:0007165 signal transduction PMID:15496141 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000036555 smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse) mSMAD2/iso:Long/PhosUbiq:1|UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148 NOT enables GO:0003713 transcription coactivator activity PMID:15496141 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:000036556 smad2 isoform Short acetylated and phosphorylated 1 (human) hSMAD2/iso:Short/AcPhos:1|UniProtKB:Q15796-2, Lys-19, MOD:00394|Ser-435/Ser-437, MOD:00046 enables GO:0003677 DNA binding PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000036556 smad2 isoform Short acetylated and phosphorylated 1 (human) hSMAD2/iso:Short/AcPhos:1|UniProtKB:Q15796-2, Lys-19, MOD:00394|Ser-435/Ser-437, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000036556 smad2 isoform Short acetylated and phosphorylated 1 (human) hSMAD2/iso:Short/AcPhos:1|UniProtKB:Q15796-2, Lys-19, MOD:00394|Ser-435/Ser-437, MOD:00046 increased enables GO:0003700 DNA-binding transcription factor activity PR:000000656 PMID:17074756 IDA NCBITaxon:9606 UniProtKB:Q15796-2 20080301 PRO:CNA PR:000036557 smad3 isoform 1 acetylated and phosphorylated 1 (human) hSMAD3/iso:1/AcPhos:1|UniProtKB:P84022-1, Lys-19, MOD:00394|Ser-423/Ser-425, MOD:00046 enables GO:0003700 DNA-binding transcription factor activity PMID:17074756 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000036557 smad3 isoform 1 acetylated and phosphorylated 1 (human) hSMAD3/iso:1/AcPhos:1|UniProtKB:P84022-1, Lys-19, MOD:00394|Ser-423/Ser-425, MOD:00046 located_in GO:0005634 nucleus PMID:17074756 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000036557 smad3 isoform 1 acetylated and phosphorylated 1 (human) hSMAD3/iso:1/AcPhos:1|UniProtKB:P84022-1, Lys-19, MOD:00394|Ser-423/Ser-425, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17074756 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:000036558 smad3 isoform 1 phosphorylated 1 (mouse) mSMAD3/iso:1/Phos:1|UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 enables GO:0003690 double-stranded DNA binding PMID:15282343 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036558 smad3 isoform 1 phosphorylated 1 (mouse) mSMAD3/iso:1/Phos:1|UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 enables GO:0003700 DNA-binding transcription factor activity PMID:10823886|PMID:12943993 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036558 smad3 isoform 1 phosphorylated 1 (mouse) mSMAD3/iso:1/Phos:1|UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 enables GO:0008134 transcription factor binding PMID:15464984|PMID:9702197 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036558 smad3 isoform 1 phosphorylated 1 (mouse) mSMAD3/iso:1/Phos:1|UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 located_in GO:0005634 nucleus PMID:12943993|PMID:15282343 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036558 smad3 isoform 1 phosphorylated 1 (mouse) mSMAD3/iso:1/Phos:1|UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046 part_of GO:0005667 transcription factor complex PMID:9702197 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036560 smad3 isoform 1 phosphorylated 2 (mouse) mSMAD3/iso:1/Phos:2|UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046 decreased enables GO:0003700 DNA-binding transcription factor activity PR:000036558 PMID:15241418 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036561 smad3 isoform 1 phosphorylated 3 (mouse) mSMAD3/iso:1/Phos:3|UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046 located_in GO:0005737 cytoplasm PMID:10197981 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036561 smad3 isoform 1 phosphorylated 3 (mouse) mSMAD3/iso:1/Phos:3|UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046 NOT enables GO:0003713 transcription coactivator activity PMID:10197981 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:000036562 smad5 isoform 1 phosphorylated 1 (human) hSMAD5/iso:1/Phos:1|UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135 IDA NCBITaxon:9606 UniProtKB:Q99717-1 20080301 PRO:CNA PR:000036562 smad5 isoform 1 phosphorylated 1 (human) hSMAD5/iso:1/Phos:1|UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8637600 IDA NCBITaxon:9606 UniProtKB:Q99717-1 20080301 PRO:CNA PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse) mSMAD5/iso:1/Phos:1|UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046 located_in GO:0005634 nucleus PMID:10504300|PMID:9759503 IDA NCBITaxon:10090 UniProtKB:P97454-1 20080301 PRO:CNA PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse) mSMAD5/iso:1/Phos:1|UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:16522160 IDA NCBITaxon:10090 UniProtKB:P97454-1 20080301 PRO:CNA PR:000036564 smad6 isoform 1 dimethylated 1 (mouse) mSMAD6/iso:1/Me2:1|UniProtKB:O35182-1, Arg-74, MOD:00783 enables GO:0140416 transcription regulator inhibitor activity PMID:17118358 IDA NCBITaxon:10090 UniProtKB:O35182-1 20080301 PRO:CNA PR:000036565 smad7 isoform 1 acetylated 1 (human) hSMAD7/iso:1/Ac:1|UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064 enables GO:0140416 transcription regulator inhibitor activity PMID:12408818 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:000036565 smad7 isoform 1 acetylated 1 (human) hSMAD7/iso:1/Ac:1|UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064 located_in GO:0005634 nucleus PMID:11278814 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:000036565 smad7 isoform 1 acetylated 1 (human) hSMAD7/iso:1/Ac:1|UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12408818 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:000036567 smad9 isoform 1 phosphorylated 1 (mouse) mSMAD9/iso:1/Phos:1|UniProtKB:Q9JIW5-1, Ser-428/Ser-430, MOD:00046 enables GO:0005515 protein binding PMID:11163184|PMID:15542835 IPI NCBITaxon:10090 UniProtKB:Q9JIW5-1 20080301 PRO:CNA PR:000036567 smad9 isoform 1 phosphorylated 1 (mouse) mSMAD9/iso:1/Phos:1|UniProtKB:Q9JIW5-1, Ser-428/Ser-430, MOD:00046 located_in GO:0005634 nucleus PMID:10814522 IDA NCBITaxon:10090 UniProtKB:Q9JIW5-1 20080301 PRO:CNA PR:000036567 smad9 isoform 1 phosphorylated 1 (mouse) mSMAD9/iso:1/Phos:1|UniProtKB:Q9JIW5-1, Ser-428/Ser-430, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:11163184|PMID:15542835 IDA NCBITaxon:10090 UniProtKB:Q9JIW5-1 20080301 PRO:CNA PR:000036568 potassium voltage-gated channel subfamily A member 5 isoform 1 sequence variant E375* (human) hKCNA5/iso:1/var:E375*|UniProtKB:P22460-1, 1-374 NOT|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:16772329 IDA NCBITaxon:9606 UniProtKB:P22460-1 20080601 PRO:CNA PR:000036569 cGMP-gated cation channel alpha-1 isoform 1 phosphorylated 1 (cow) cow-CNGA1/iso:1/Phos:1|UniProtKB:Q00194-1, Tyr-498, MOD:00048 decreased enables GO:0030553 cGMP binding PR:000002593 PMID:10366613 IDA NCBITaxon:9913 UniProtKB:Q00194-1 20080601 PRO:CNA PR:000036570 platelet-derived growth factor C isoform 1 cleaved 1 (human) hPDGFC/iso:1/Clv:1|UniProtKB:Q9NRA1-1, 226-345 enables GO:0005102 signaling receptor binding PMID:10806482|PMID:11297552 IDA NCBITaxon:9606 UniProtKB:Q9NRA1-1 20080601 PRO:CNA PR:000036570 platelet-derived growth factor C isoform 1 cleaved 1 (human) hPDGFC/iso:1/Clv:1|UniProtKB:Q9NRA1-1, 226-345 enables GO:0008083 growth factor activity PMID:10806482|PMID:11297552 IDA NCBITaxon:9606 UniProtKB:Q9NRA1-1 20080601 PRO:CNA PR:000036570 platelet-derived growth factor C isoform 1 cleaved 1 (human) hPDGFC/iso:1/Clv:1|UniProtKB:Q9NRA1-1, 226-345 located_in GO:0005615 extracellular space PMID:15911618 IDA NCBITaxon:9606 UniProtKB:Q9NRA1-1 20080601 PRO:CNA PR:000036571 platelet-derived growth factor C isoform 1 cleaved 1 (mouse) mPDGFC/iso:1/Clv:1|UniProtKB:Q8CI19-1, 226-345 located_in GO:0005615 extracellular space PMID:15372073 IDA NCBITaxon:10090 UniProtKB:Q8CI19-1 20080601 PRO:CNA PR:000036571 platelet-derived growth factor C isoform 1 cleaved 1 (mouse) mPDGFC/iso:1/Clv:1|UniProtKB:Q8CI19-1, 226-345 acts_upstream_of_or_within GO:0042060 wound healing PMID:11297552 IDA NCBITaxon:10090 UniProtKB:Q8CI19-1 20080601 PRO:CNA PR:000036572 platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form (human) hPDGFC/iso:1/Sumo:1|UniProtKB:Q9NRA1-1, Lys-314, MOD:01149 located_in GO:0005634 nucleus PMID:16443219 IDA NCBITaxon:9606 UniProtKB:Q9NRA1-1 20080601 PRO:CNA PR:000036573 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse) mHCN1/iso:1/NGlyco:1|UniProtKB:O88704-1, Asn-327, MOD:00160 located_in GO:0009986 cell surface PMID:12928435 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:000036574 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 N-glycosylated 1 (mouse) mHCN2/iso:1/NGlyco:1|UniProtKB:O88703-1, Asn-380, MOD:00160 located_in GO:0009986 cell surface PMID:12928435 IDA NCBITaxon:10090 UniProtKB:O88703-1 20100711 PRO:CNA PR:000036575 voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat) rKCNC1/iso:2/Phos:1|rKCNC1/iso:Long/Phos:1|UniProtKB:P25122-1, Ser-503, MOD:00046|voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1 (rat) located_in GO:0016020 membrane PMID:16595659 IDA NCBITaxon:10116 UniProtKB:P25122-1 20090219 PRO:CNA PR:000036575 voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat) rKCNC1/iso:2/Phos:1|rKCNC1/iso:Long/Phos:1|UniProtKB:P25122-1, Ser-503, MOD:00046|voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1 (rat) decreased|contributes_to enables GO:0005249 voltage-gated potassium channel activity PR:000002649 PMID:16595659 IDA NCBITaxon:10116 UniProtKB:P25122-1 20090219 PRO:CNA PR:000036576 voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human) hKCNC4/iso:2/Phos:1|UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046 decreased|contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PR:000002655 PMID:7993631|PMID:9649584 IDA NCBITaxon:9606 UniProtKB:Q03721-2 20080601 PRO:CNA PR:000036578 voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse) mKCND2/iso:1/Phos:2|UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047 located_in GO:0030425 dendrite PMID:11040264 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:000036579 voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse) mKCND2/iso:1/Phos:3|UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046 located_in GO:0030425 dendrite PMID:11040264 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:000036580 voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse) mKCND2/iso:1/Phos:4|UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046 located_in GO:0009986 cell surface PMID:16251476 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:000036580 voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse) mKCND2/iso:1/Phos:4|UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046 located_in GO:0030425 dendrite PMID:11040264 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:000036580 voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse) mKCND2/iso:1/Phos:4|UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046 decreased|contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PR:000002656 PMID:16251476 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:000036581 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human) hKCNH2/iso:1/Glyco:1|hKCNH2/iso:A/NGlyco:1|UniProtKB:Q12809-1, Asn-598, MOD:00160|voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human) located_in GO:0009986 cell surface PMID:12063277 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20080601 PRO:CNA PR:000036581 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human) hKCNH2/iso:1/Glyco:1|hKCNH2/iso:A/NGlyco:1|UniProtKB:Q12809-1, Asn-598, MOD:00160|voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:12063277 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20080601 PRO:CNA PR:000036582 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (mouse) mKCNH2/iso:1/Glyco:1|mKCNH2/iso:A/NGlyco:1|UniProtKB:O35219-1, Asn-600, MOD:00160|voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (mouse) located_in GO:0005886 plasma membrane MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 UniProtKB:O35219-1 20080601 PRO:CNA PR:000036583 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human) hKCNH2/iso:1/Phos:1|hKCNH2/iso:A/Phos:1|voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:10837251 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20080601 PRO:CNA PR:000036583 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human) hKCNH2/iso:1/Phos:1|hKCNH2/iso:A/Phos:1|voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human) decreased enables GO:0005251 delayed rectifier potassium channel activity PR:000002666 PMID:10837251 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20080601 PRO:CNA PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human) hKCNA2/iso:1/Phos:1|UniProtKB:P16389-1, Tyr-132, MOD:00048 located_in GO:0005768 endosome PMID:15215309 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human) hKCNA2/iso:1/Phos:1|UniProtKB:P16389-1, Tyr-132, MOD:00048 NOT enables GO:0005251 delayed rectifier potassium channel activity PMID:15215309 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse) mKCNA2/iso:1/Phos:2|UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046 located_in GO:0009986 cell surface PMID:18056633 IDA NCBITaxon:10090 UniProtKB:P63141-1 20080601 PRO:CNA PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse) mKCNA2/iso:1/Phos:2|UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046 part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633 IDA NCBITaxon:10090 UniProtKB:P63141-1 20080601 PRO:CNA PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat) rKCNA2/iso:1/Phos:2|UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046 located_in GO:0009986 cell surface PMID:18056633 IDA NCBITaxon:10116 UniProtKB:P63142-1 20080601 PRO:CNA PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat) rKCNA2/iso:1/Phos:2|UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046 part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633 IDA NCBITaxon:10116 UniProtKB:P63142-1 20080601 PRO:CNA PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human) hKCNA2/iso:1/Phos:2|UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046 located_in GO:0009986 cell surface PMID:18056633 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human) hKCNA2/iso:1/Phos:2|UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046 part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:000036589 ezrin isoform 1 phosphorylated 2 (human) hEZR/iso:1/Phos:2|UniProtKB:P15311-1, Ser-66, MOD:00046 enables GO:0005515 protein binding PR:000002696 PMID:16438931 IPI NCBITaxon:9606 UniProtKB:P15311-1 20080922 PRO:CNA PR:000036590 ezrin isoform 1 phosphorylated 3 (human) hEZR/iso:1/Phos:3|UniProtKB:P15311-1, Tyr-191, MOD:00048 enables GO:0005515 protein binding PR:P00523-1 PMID:15647376 IPI NCBITaxon:9606 UniProtKB:P15311-1 20080922 PRO:CNA PR:000036592 ezrin isoform 1 phosphorylated 5 (human) hEZR/iso:1/Phos:5|UniProtKB:P15311-1, Thr-567, MOD:00047 enables GO:0005515 protein binding PR:P43403 PMID:18025306 IPI NCBITaxon:9606 UniProtKB:P15311-1 20090717 PRO:AL PR:000036592 ezrin isoform 1 phosphorylated 5 (human) hEZR/iso:1/Phos:5|UniProtKB:P15311-1, Thr-567, MOD:00047 located_in GO:0001772 immunological synapse PMID:18025306 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090717 PRO:AL PR:000036592 ezrin isoform 1 phosphorylated 5 (human) hEZR/iso:1/Phos:5|UniProtKB:P15311-1, Thr-567, MOD:00047 located_in GO:0045177 apical part of cell PMID:16144865 IDA NCBITaxon:9606 UniProtKB:P15311-1 20081015 PRO:CNA PR:000036592 ezrin isoform 1 phosphorylated 5 (human) hEZR/iso:1/Phos:5|UniProtKB:P15311-1, Thr-567, MOD:00047 acts_upstream_of_or_within GO:0001771 immunological synapse formation PMID:18025306 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090717 PRO:AL PR:000036592 ezrin isoform 1 phosphorylated 5 (human) hEZR/iso:1/Phos:5|UniProtKB:P15311-1, Thr-567, MOD:00047 acts_upstream_of_or_within GO:0051279 regulation of release of sequestered calcium ion into cytosol PMID:18025306 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090717 PRO:AL PR:000036594 cftr isoform 1 phosphorylated 1 (human) hCFTR/iso:1/Phos:1|UniProtKB:P13569-1, Ser-737/Ser-768/Ser-795/Ser-813, MOD:00046 enables GO:0005260 intracellularly ATP-gated chloride channel activity PMID:14602047 IDA NCBITaxon:9606 UniProtKB:P13569-1 20080601 PRO:CNA PR:000036594 cftr isoform 1 phosphorylated 1 (human) hCFTR/iso:1/Phos:1|UniProtKB:P13569-1, Ser-737/Ser-768/Ser-795/Ser-813, MOD:00046 enables GO:0005260 intracellularly ATP-gated chloride channel activity PMID:1716180 IDA NCBITaxon:9606 UniProtKB:P13569-1 20080601 PRO:CNA PR:000036596 CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human) hCD2/iso:1/SigPep-/NGlyco:1|UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160 enables GO:0005515 protein binding PR:P19256 PMID:7544493|PMID:7688025 IPI NCBITaxon:9606 UniProtKB:P06729-1 20080922 PRO:CNA PR:000036596 CD2 molecule isoform 1, signal peptide removed N-glycosylated 1 (human) hCD2/iso:1/SigPep-/NGlyco:1|UniProtKB:P06729-1, 25-351, Asn-89, MOD:00160 acts_upstream_of_or_within GO:0007155 cell adhesion PMID:1385399 IDA NCBITaxon:9606 UniProtKB:P06729-1 20080922 PRO:CNA PR:000036597 interleukin-1 alpha isoform 1 cleaved 1 (human) hIL1A/iso:1/Clv:1|PRO_0000015266|UniProtKB:P01583-1, 113-271 located_in GO:0005615 extracellular space PMID:3281727 IDA NCBITaxon:9606 UniProtKB:P01583-1 20080922 PRO:CNA PR:000036598 interleukin-1 alpha isoform 1 myristoylated 1 (human) hIL1A/iso:1/Myr:1|UniProtKB:P01583-1, Lys-83, MOD:00087 located_in GO:0016020 membrane PMID:8346241 IDA NCBITaxon:9606 UniProtKB:P01583-1 20080922 PRO:CNA PR:000036599 interleukin-1 alpha isoform 1 myristoylated 2 (human) hIL1A/iso:1/Myr:2|UniProtKB:P01583-1, Lys-82, MOD:00087 located_in GO:0016020 membrane PMID:8346241 IDA NCBITaxon:9606 UniProtKB:P01583-1 20080922 PRO:CNA PR:000036600 interleukin-1 alpha isoform 1 phosphorylated 1 (mouse) mIL1A/iso:1/Phos:1|UniProtKB:P01582-1, Ser-90, MOD:00046 located_in GO:0016020 membrane PMID:3126184 IDA NCBITaxon:10090 UniProtKB:P01582-1 20080922 PRO:CNA PR:000036601 interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human) hIL1RN/iso:1/SigPep-|PRO_0000015328|UniProtKB:P18510-1, 26-177 enables GO:0045352 interleukin-1 type I receptor antagonist activity PMID:2139180 IDA NCBITaxon:9606 UniProtKB:P18510-1 20080922 PRO:CNA PR:000036601 interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human) hIL1RN/iso:1/SigPep-|PRO_0000015328|UniProtKB:P18510-1, 26-177 located_in GO:0005615 extracellular space PMID:2139180 IDA NCBITaxon:9606 UniProtKB:P18510-1 20080922 PRO:CNA PR:000036602 interleukin-17A, signal peptide removed form (human) hIL17A/SigPep-|PRO_0000015423|UniProtKB:Q16552, 24-155 enables GO:0005125 cytokine activity PMID:7499828 EXP NCBITaxon:9606 UniProtKB:Q16552-1 20080922 PRO:CNA PR:000036602 interleukin-17A, signal peptide removed form (human) hIL17A/SigPep-|PRO_0000015423|UniProtKB:Q16552, 24-155 enables GO:0042803 protein homodimerization activity PMID:15055556 TAS NCBITaxon:9606 UniProtKB:Q16552-1 20080922 PRO:CNA PR:000036602 interleukin-17A, signal peptide removed form (human) hIL17A/SigPep-|PRO_0000015423|UniProtKB:Q16552, 24-155 located_in GO:0005615 extracellular space PMID:15340161|PMID:7499828 IDA NCBITaxon:9606 UniProtKB:Q16552-1 20080922 PRO:CNA PR:000036603 adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat) rADGRL1/iso:4/Clv:1|UniProtKB:O88917-4, 25-837 located_in GO:0016020 membrane PMID:12270923 IDA NCBITaxon:10116 UniProtKB:O88917-4 20080915 PRO:CNA PR:000036603 adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat) rADGRL1/iso:4/Clv:1|UniProtKB:O88917-4, 25-837 part_of GO:0043235 receptor complex PMID:12270924|PMID:9208860 IDA NCBITaxon:10116 PR:000001275 UniProtKB:O88917-4 20080915 PRO:CNA PR:000036603 adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat) rADGRL1/iso:4/Clv:1|UniProtKB:O88917-4, 25-837 contributes_to enables GO:0016524 latrotoxin receptor activity PMID:12270924|PMID:9208860 IDA NCBITaxon:10116 UniProtKB:O88917-4 20080915 PRO:CNA PR:000036604 adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat) rADGRL1/iso:4/Clv:2|UniProtKB:O88917-4, 838-1471 part_of GO:0043235 receptor complex PMID:12270924|PMID:9208860 IDA NCBITaxon:10116 PR:000001274 UniProtKB:O88917-4 20080915 PRO:CNA PR:000036604 adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat) rADGRL1/iso:4/Clv:2|UniProtKB:O88917-4, 838-1471 contributes_to enables GO:0016524 latrotoxin receptor activity PMID:12270924|PMID:9208860 IDA NCBITaxon:10116 UniProtKB:O88917-4 20080915 PRO:CNA PR:000036605 Muellerian-inhibiting factor isoform 1 cleaved 1 (human) hAMH/iso:1/Clv:1|UniProtKB:P03971-1, 451-560 enables GO:0046983 protein dimerization activity PMID:14673134 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:000036606 Muellerian-inhibiting factor isoform 1 cleaved 1 (rat) rAMH/iso:1/Clv:1|UniProtKB:P49000-1, 446-553 located_in GO:0005576 extracellular region PMID:8755541 IDA NCBITaxon:10116 UniProtKB:P49000-1 20080301 PRO:CNA PR:000036608 inhibin alpha chain isoform 1 cleaved and N-glycosylated 2 (human) hINHA/iso:1/ClvNGlyco:2|PRO_0000033687, Asn-268/Asn-302, MOD:00160|UniProtKB:P05111-1, 233-366, Asn-268/Asn-302, MOD:00160 located_in GO:0005615 extracellular space PMID:17456790|PMID:8885240 EXP NCBITaxon:9606 UniProtKB:P05111-1 20090203 PRO:CNA PR:000036608 inhibin alpha chain isoform 1 cleaved and N-glycosylated 2 (human) hINHA/iso:1/ClvNGlyco:2|PRO_0000033687, Asn-268/Asn-302, MOD:00160|UniProtKB:P05111-1, 233-366, Asn-268/Asn-302, MOD:00160 part_of GO:0043512 inhibin A complex PR:000036540 PMID:17456790|PMID:8885240 IPI NCBITaxon:9606 UniProtKB:P05111-1 20090203 PRO:CNA PR:000036609 inhibin alpha chain isoform 1 cleaved 1 (human) hINHA/iso:1/Clv:1|PRO_0000033687|UniProtKB:P05111-1, 233-366 NOT part_of GO:0043512 inhibin A complex PMID:17456790 EXP NCBITaxon:9606 UniProtKB:P05111-1 20090203 PRO:CNA PR:000036615 CD14 molecule cleaved 1 soluble form (human) hCD14/iso:1/Clv:1/soluble|PRO_0000020884|UniProtKB:P08571-1, 20-367 located_in GO:0005576 extracellular region PMID:7519994 EXP NCBITaxon:9606 UniProtKB:P08571-1 20090326 PRO:CNA PR:000036619 tyrosine-protein kinase Lck isoform 1 phosphorylated 1 (human) hLCK/iso:1/Phos:1|UniProtKB:P06239-1, Tyr-394/Tyr-505, MOD:00048 decreased enables GO:0016301 kinase activity PR:000036622 PMID:9043947 EXP NCBITaxon:9606 UniProtKB:P06239-1 20090709 PRO:CL Note=This form is enhanced by HIV gp120. PR:000036620 tyrosine-protein kinase Fyn isoform 1 phosphorylated 1 (human) hFYN/iso:1/Phos:1 enables GO:0005515 protein binding GO:0042101 PMID:9043947 IPI NCBITaxon:9606 UniProtKB:P06241-1 20090709 PRO:CL Note=HIV gp120 inhibits TCR-CD3 mediated phosphorylation of fyn. PR:000036620 tyrosine-protein kinase Fyn isoform 1 phosphorylated 1 (human) hFYN/iso:1/Phos:1 enables GO:0016301 kinase activity PMID:9043947 EXP NCBITaxon:9606 UniProtKB:P06241-1 20090709 PRO:CL Note=HIV gp120 inhibits TCR-CD3 mediated phosphorylation of fyn. PR:000036621 moesin isoform 1 phosphorylated 1 (human) hMSN/iso:1/Phos:1|UniProtKB:P26038-1, Thr-558, MOD:00047 enables GO:0005515 protein binding PR:P16150 PMID:18025306 IPI NCBITaxon:9606 UniProtKB:P26038-1 20090709 PRO:AL PR:000036621 moesin isoform 1 phosphorylated 1 (human) hMSN/iso:1/Phos:1|UniProtKB:P26038-1, Thr-558, MOD:00047 located_in GO:0005938 cell cortex PMID:18025306 EXP NCBITaxon:9606 UniProtKB:P26038-1 20090709 PRO:AL PR:000036621 moesin isoform 1 phosphorylated 1 (human) hMSN/iso:1/Phos:1|UniProtKB:P26038-1, Thr-558, MOD:00047 acts_upstream_of_or_within GO:0001771 immunological synapse formation PMID:18025306 EXP NCBITaxon:9606 UniProtKB:P26038-1 20090709 PRO:AL PR:000036622 tyrosine-protein kinase Lck isoform 1 phosphorylated 2 (human) hLCK/iso:1/Phos:2|UniProtKB:P06239-1, Tyr-394, MOD:00048 enables GO:0016301 kinase activity PMID:9043947 EXP NCBITaxon:9606 UniProtKB:P06239-1 20090709 PRO:CL Note=HIV gp120 inhibits TCR-CD3 mediated phosphorylation of fyn. PR:000036622 tyrosine-protein kinase Lck isoform 1 phosphorylated 2 (human) hLCK/iso:1/Phos:2|UniProtKB:P06239-1, Tyr-394, MOD:00048 enables GO:0044877 protein-containing complex binding PMID:9043947 IPI NCBITaxon:9606 UniProtKB:P06239-1 20100930 PRO:CL Note=Binds TCR-CD3 complex. PR:000036624 cellular tumor antigen p53 isoform 1 phosphorylated 2 (human) hTP53/iso:1/Phos:2|UniProtKB:P04637-1, Ser-15/Ser-46, MOD:00046 enables GO:0005515 protein binding PR:000003109 PMID:15642743 IPI NCBITaxon:9606 UniProtKB:P04637-1 20090717 PRO:CL Note=Induced by HIV gp120/gp41. PR:000036624 cellular tumor antigen p53 isoform 1 phosphorylated 2 (human) hTP53/iso:1/Phos:2|UniProtKB:P04637-1, Ser-15/Ser-46, MOD:00046 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:15642743 EXP NCBITaxon:9606 UniProtKB:P04637-1 20090717 PRO:CL Note=This form is induced by HIV gp120/gp41. PR:000036625 ezrin isoform 1 phosphorylated 6 (human) hEZR/iso:1/Phos:6|UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047 enables GO:0003779 actin binding PMID:18852256 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090713 PRO:AL PR:000036625 ezrin isoform 1 phosphorylated 6 (human) hEZR/iso:1/Phos:6|UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047 located_in GO:0002102 podosome PMID:18852256 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090713 PRO:AL PR:000036625 ezrin isoform 1 phosphorylated 6 (human) hEZR/iso:1/Phos:6|UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047 located_in GO:0005886 plasma membrane PMID:18852256 EXP NCBITaxon:9606 UniProtKB:P15311-1 20090713 PRO:AL PR:000036626 kinesin-like protein KIF11 isoform 1 phosphorylated 1 (human) hKIF11/iso:1/Phos:1|UniProtKB:P52732-1, Thr-926, MOD:00047 located_in GO:0005874 microtubule PMID:19001501 EXP NCBITaxon:9606 UniProtKB:P52732-1 20090709 PRO:AL PR:000036626 kinesin-like protein KIF11 isoform 1 phosphorylated 1 (human) hKIF11/iso:1/Phos:1|UniProtKB:P52732-1, Thr-926, MOD:00047 acts_upstream_of_or_within GO:0000073 initial mitotic spindle pole body separation PMID:19001501 EXP NCBITaxon:9606 UniProtKB:P52732-1 20090709 PRO:AL PR:000036626 kinesin-like protein KIF11 isoform 1 phosphorylated 1 (human) hKIF11/iso:1/Phos:1|UniProtKB:P52732-1, Thr-926, MOD:00047 acts_upstream_of_or_within GO:0051299 centrosome separation PMID:19001501 EXP NCBITaxon:9606 UniProtKB:P52732-1 20090709 PRO:AL PR:000036627 transmembrane protease serine 9 isoform 3 cleaved 1 (mouse) mTMPRSS9/iso:3/Clv:1|UniProtKB:Q0X0F1, 83-620 enables GO:0008233 peptidase activity PMID:16872279 EXP NCBITaxon:10090 UniProtKB:Q0X0F1 20090709 PRO:CL PR:000036627 transmembrane protease serine 9 isoform 3 cleaved 1 (mouse) mTMPRSS9/iso:3/Clv:1|UniProtKB:Q0X0F1, 83-620 located_in GO:0005615 extracellular space PMID:16872279 EXP NCBITaxon:10090 UniProtKB:Q0X0F1 20090709 PRO:CL PR:000036628 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human) hCD247/iso:CD3 zeta/Phos:1 located_in GO:0005886 plasma membrane PMID:9043947 EXP NCBITaxon:9606 UniProtKB:P20963-1 20090810 PRO:CL Note=Phosphorylated on Tyr residues of its Reth motifs. Phosphorylated by fyn and lck which are mediated by TCR-CD3 which is inhibited by HIV gp120. PR:000036628 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human) hCD247/iso:CD3 zeta/Phos:1 acts_upstream_of_or_within GO:0050852 T cell receptor signaling pathway PMID:9043947 EXP NCBITaxon:9606 UniProtKB:P20963-1 20090810 PRO:CL PR:000036629 tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human) hZAP70/iso:1/Phos:1 acts_upstream_of_or_within GO:0090630 activation of GTPase activity PMID:9269777 EXP NCBITaxon:9606 UniProtKB:P43403-1 20090810 PRO:CL Note=This form is induced by HIV gp160 and CD4 ligation. PR:000036630 CD4 molecule isoform 1 phosphorylated 1 (human) hCD4/iso:1/Phos:1 enables GO:0001618 virus receptor activity PMID:3259291 EXP NCBITaxon:9606 UniProtKB:P01730-1 20090810 PRO:CL PR:000036630 CD4 molecule isoform 1 phosphorylated 1 (human) hCD4/iso:1/Phos:1 enables GO:0005515 protein binding PR:000003229 PMID:3259291 IPI NCBITaxon:9606 UniProtKB:P01730-1 20090810 PRO:CL PR:000036631 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 1 (human) hNRP1/iso:1/ClvOGlyco:1|PRO_0000021859, Ser-612, MOD:00215|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00215 enables GO:0043184 vascular endothelial growth factor receptor 2 binding PR:P35968 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036631 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 1 (human) hNRP1/iso:1/ClvOGlyco:1|PRO_0000021859, Ser-612, MOD:00215|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00215 acts_upstream_of_or_within GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549 EXP NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036631 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 1 (human) hNRP1/iso:1/ClvOGlyco:1|PRO_0000021859, Ser-612, MOD:00215|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00215 increased enables GO:0005515 protein binding PR:000036635 PR:P15692-4 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036632 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 2 (human) hNRP1/iso:1/ClvOGlyco:2|PRO_0000021859, Ser-612, MOD:00213|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00213 acts_upstream_of_or_within GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549 EXP NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036632 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 2 (human) hNRP1/iso:1/ClvOGlyco:2|PRO_0000021859, Ser-612, MOD:00213|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00213 decreased enables GO:0043184 vascular endothelial growth factor receptor 2 binding PR:000036635 PR:P35968 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036632 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 2 (human) hNRP1/iso:1/ClvOGlyco:2|PRO_0000021859, Ser-612, MOD:00213|UniProtKB:O14786-1, 22-923, Ser-612, MOD:00213 increased enables GO:0005515 protein binding PR:000036635 PR:P15692-4 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036633 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse) mBCL2/iso:1/Phos:1|UniProtKB:P10417-1, Ser-70, MOD:00046 enables GO:0005515 protein binding PR:Q07813 PMID:9115213|PMID:9852076 IPI NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:000036633 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse) mBCL2/iso:1/Phos:1|UniProtKB:P10417-1, Ser-70, MOD:00046 enables GO:0019902 phosphatase binding PR:P67774 PMID:9115213|PMID:9852076 IPI NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:000036633 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse) mBCL2/iso:1/Phos:1|UniProtKB:P10417-1, Ser-70, MOD:00046 located_in GO:0016020 membrane PMID:9115213|PMID:9852076 EXP NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:000036633 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse) mBCL2/iso:1/Phos:1|UniProtKB:P10417-1, Ser-70, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:9115213|PMID:9852076 EXP NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 enables GO:0005515 protein binding PR:P31946 PMID:15057270 IPI NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 enables GO:0005515 protein binding PR:P61981 PMID:15057270 IPI NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 enables GO:0005515 protein binding PR:P62258 PMID:15057270 IPI NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 located_in GO:0005737 cytoplasm PMID:15057270 EXP NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 located_in GO:0005829 cytosol PMID:12244301 EXP NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:12244301 EXP NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036634 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human) hCDKN1B/iso:1/Phos:1|UniProtKB:P46527-1, Thr-157, MOD:00047 decreased enables GO:0005515 protein binding PR:000003092 PR:P52294 PMID:15057270 IPI NCBITaxon:9606 UniProtKB:P46527-1 20090717 PRO:JAN PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human) hNRP1/iso:1/SigPep-|PRO_0000021859|UniProtKB:O14786-1, 22-923 enables GO:0005515 protein binding PR:P15692-4 PMID:11986311 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090717 PRO:JAN PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human) hNRP1/iso:1/SigPep-|PRO_0000021859|UniProtKB:O14786-1, 22-923 enables GO:0005515 protein binding PR:P15692-4 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human) hNRP1/iso:1/SigPep-|PRO_0000021859|UniProtKB:O14786-1, 22-923 enables GO:0005515 protein binding PR:P49763-3 PMID:11986311 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090717 PRO:JAN PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human) hNRP1/iso:1/SigPep-|PRO_0000021859|UniProtKB:O14786-1, 22-923 enables GO:0008201 heparin binding PMID:11986311 EXP NCBITaxon:9606 UniProtKB:O14786-1 20090717 PRO:JAN PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human) hNRP1/iso:1/SigPep-|PRO_0000021859|UniProtKB:O14786-1, 22-923 enables GO:0043184 vascular endothelial growth factor receptor 2 binding PR:P35968 PMID:16763549 IPI NCBITaxon:9606 UniProtKB:O14786-1 20090810 PRO:JAN PR:000036636 vascular endothelial growth factor B isoform 1 cleaved 1 (mouse) mVEGFB/iso:1/Clv:1|UniProtKB:P49766-1, 22-127 enables GO:0005515 protein binding PR:P97333 PMID:10409677 IPI NCBITaxon:10090 UniProtKB:P49766-1 20090717 PRO:CNA PR:000036637 mitogen-activated protein kinase 14 phosphorylated 1 (human) hMAPK14/Phos:1|UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048 enables GO:0004707 MAP kinase activity PMID:15642743 EXP NCBITaxon:9606 UniProtKB:Q16539-1 20090717 PRO:CL PR:000036637 mitogen-activated protein kinase 14 phosphorylated 1 (human) hMAPK14/Phos:1|UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048 enables GO:0005515 protein binding PR:000036624 PMID:15642743 IPI NCBITaxon:9606 UniProtKB:Q16539-1 20090717 PRO:CL PR:000036637 mitogen-activated protein kinase 14 phosphorylated 1 (human) hMAPK14/Phos:1|UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:15642743 EXP NCBITaxon:9606 UniProtKB:Q16539-1 20090717 PRO:CL PR:000036638 nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 (human) hNFATC1/iso:1/Phos:1|UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046 enables GO:0005515 protein binding PR:O14980 PMID:10866678 IPI NCBITaxon:9606 UniProtKB:O95644-1 20090714 PRO:JAN PR:000036638 nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 (human) hNFATC1/iso:1/Phos:1|UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046 located_in GO:0005737 cytoplasm PMID:10866678 EXP NCBITaxon:9606 UniProtKB:O95644-1 20090714 PRO:JAN PR:000036639 voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human) hKCNA3/iso:1/Phos:1 decreased enables GO:0015271 outward rectifier potassium channel activity PR:000002682 PMID:9989602 EXP NCBITaxon:9606 UniProtKB:P22001-1 20090717 PRO:CL PR:000036641 Bcl-2-like protein 11 isoform 2 phosphorylated 1 (human) hBCL2L11/iso:2/Phos:1|UniProtKB:O43521-2, Ser-44/Ser-58, MOD:00046|Thr-56, MOD:00047 acts_upstream_of_or_within GO:0012501 programmed cell death PMID:12591950 EXP NCBITaxon:9606 UniProtKB:O43521-2 20090918 PRO:JAN PR:000036641 Bcl-2-like protein 11 isoform 2 phosphorylated 1 (human) hBCL2L11/iso:2/Phos:1|UniProtKB:O43521-2, Ser-44/Ser-58, MOD:00046|Thr-56, MOD:00047 decreased enables GO:0005515 protein binding PR:000002835 PR:Q96QB1 PMID:12591950 IPI NCBITaxon:9606 UniProtKB:O43521-2 20090918 PRO:JAN PR:000036642 focal adhesion kinase 2 isoform 1 phosphorylated 1 (human) hPTK2B/iso:1/Phos:1|UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048 acts_upstream_of_or_within GO:0070098 chemokine-mediated signaling pathway PMID:11698270 EXP NCBITaxon:9606 UniProtKB:Q14289-1 20090918 PRO:CL Note=This form is induced by HIV gp120 exposure. PR:000036643 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human) hRAF1/iso:1/Phos:2|UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046 enables GO:0004674 protein serine/threonine kinase activity PMID:15849194 EXP NCBITaxon:9606 UniProtKB:P04049-1 20090918 PRO:JAN PR:000036643 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human) hRAF1/iso:1/Phos:2|UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046 enables GO:0005515 protein binding PR:P10415 PMID:15849194 IPI NCBITaxon:9606 UniProtKB:P04049-1 20090918 PRO:JAN PR:000036643 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human) hRAF1/iso:1/Phos:2|UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046 located_in GO:0005741 mitochondrial outer membrane PMID:15849194 EXP NCBITaxon:9606 UniProtKB:P04049-1 20090918 PRO:JAN PR:000036643 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human) hRAF1/iso:1/Phos:2|UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:15849194 EXP NCBITaxon:9606 UniProtKB:P04049-1 20090918 PRO:JAN PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse) mINPP5D/iso:2/Phos:1 enables GO:0005515 protein binding PR:P98083 PMID:8643691 IPI NCBITaxon:10090 UniProtKB:Q9ES52-2 20091007 PRO:HJD PR:000036645 PC4 and SFRS1-interacting protein p38 (human) hPSIP1/iso:2/Clv:p38|UniProtKB:O75475-2, 86-333 located_in GO:0005634 nucleus PMID:18708362 EXP NCBITaxon:9606 UniProtKB:O75475-2 20091117 PRO:CNA PR:000036645 PC4 and SFRS1-interacting protein p38 (human) hPSIP1/iso:2/Clv:p38|UniProtKB:O75475-2, 86-333 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:18708362 EXP NCBITaxon:9606 UniProtKB:O75475-2 20091117 PRO:CNA PR:000036646 dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (human) hMAP2K3/iso:2/Phos:1|UniProtKB:P46734-2, Ser-189, MOD:00046|Thr-193, MOD:00047 enables GO:0004708 MAP kinase kinase activity PMID:8622669 EXP NCBITaxon:9606 UniProtKB:P46734-2 20100120 PRO:CNA PR:000036647 cholera enterotoxin subunit A1 (Vibrio cholerae O1 biovar El Tor str. N16961) ctxA/Clv:A1 (VIBCH)|PRO_0000019342|UniProtKB:P01555, 19-212 acts_upstream_of_or_within GO:0035821 modulation of process of another organism PMID:13679513 EXP NCBITaxon:666 UniProtKB:P01555-1 20100120 PRO:CNA PR:000036648 cholera enterotoxin subunit A2 (Vibrio cholerae O1 biovar El Tor str. N16961) ctxA/Clv:A2 (VIBCH)|PRO_0000019343|UniProtKB:P01555, 213-258 acts_upstream_of_or_within GO:0035821 modulation of process of another organism PMID:13679513 EXP NCBITaxon:666 UniProtKB:P01555-1 20100120 PRO:CNA PR:000036649 receptor-interacting serine/threonine-protein kinase 1 isoform 1 ubiquitinated 1 (human) hRIPK1/iso:1/Ubiq:1 enables GO:0005515 protein binding PR:Q8C669 PMID:19734906 IPI NCBITaxon:9606 UniProtKB:Q13546-1 20100208 PRO:CNA PR:000036658 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:1|UniProtKB:P0AEC3-1, His-292, MOD:00890 enables GO:0000155 phosphorelay sensor kinase activity EcoCyc:PHOSPHO-ARCB-HIS EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036658 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:1|UniProtKB:P0AEC3-1, His-292, MOD:00890 located_in GO:0016020 membrane EcoCyc:PHOSPHO-ARCB-HIS EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036658 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:1|UniProtKB:P0AEC3-1, His-292, MOD:00890 acts_upstream_of_or_within GO:0000160 phosphorelay signal transduction system EcoCyc:PHOSPHO-ARCB-HIS EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036658 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:1|UniProtKB:P0AEC3-1, His-292, MOD:00890 acts_upstream_of_or_within GO:0018106 peptidyl-histidine phosphorylation EcoCyc:PHOSPHO-ARCB-HIS EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036663 signal transduction histidine-protein kinase BaeS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-baeS/iso:1/Phos:1|UniProtKB:P30847-1, His-250, MOD:00890 enables GO:0016772 transferase activity, transferring phosphorus-containing groups EcoCyc:PHOSPHO-BAES EXP NCBITaxon:83333 UniProtKB:P30847-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 enables GO:0004673 protein histidine kinase activity EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 enables GO:0005524 ATP binding EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 enables GO:0016772 transferase activity, transferring phosphorus-containing groups EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 acts_upstream_of_or_within GO:0000160 phosphorelay signal transduction system EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 acts_upstream_of_or_within GO:0010041 response to iron(III) ion EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036666 sensor protein BasS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-basS/iso:1/Phos:1|UniProtKB:P30844-1, His-152, MOD:00890 acts_upstream_of_or_within GO:0018106 peptidyl-histidine phosphorylation EcoCyc:PHOSPHO-BASS EXP NCBITaxon:83333 UniProtKB:P30844-1 20100331 PRO:CNA PR:000036669 chemotaxis protein CheY isoform 1, initiator methionine removed phosphorylated 1 (Escherichia coli K-12) Ec-cheY/iso:1/InitMet-/Phos:1|PRO_0000081040, Asp-57, MOD:00042|UniProtKB:P0AE67-1, 2-129, Asp-57, MOD:00042 acts_upstream_of_or_within GO:0006473 protein acetylation EcoCyc:PHOSPHO-CHEY EXP NCBITaxon:83333 UniProtKB:P0AE67-1 20100331 PRO:CNA PR:000036671 sensor protein CreC isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-creC/iso:1/Phos:1|UniProtKB:P08401-1, His-265, MOD:00890 enables GO:0016772 transferase activity, transferring phosphorus-containing groups PMID:15522865 EXP NCBITaxon:83333 UniProtKB:P08401-1 20100331 PRO:CNA PR:000036672 sensor protein dcuS isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dcuS/iso:1/Phos:1|UniProtKB:P0AEC8-1, His-349, MOD:00890 acts_upstream_of_or_within GO:0009061 anaerobic respiration EcoCyc:PHOSPHO-DCUS-MONOMER EXP NCBITaxon:83333 UniProtKB:P0AEC8-1 20100331 PRO:CNA PR:000036682 chaperonin GroEL isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-groL/iso:1/InitMet-|PRO_0000063358|UniProtKB:P0A6F5-1, 2-548 enables GO:0042802 identical protein binding EcoCyc:EG10599-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A6F5-1 20100331 PRO:CNA PR:000036682 chaperonin GroEL isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-groL/iso:1/InitMet-|PRO_0000063358|UniProtKB:P0A6F5-1, 2-548 acts_upstream_of_or_within GO:0006457 protein folding EcoCyc:EG10599-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A6F5-1 20100331 PRO:CNA PR:000036684 elongation factor G isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-fusA/iso:1/InitMet-|PRO_0000091119|UniProtKB:P0A6M8-1, 2-704 located_in GO:0005737 cytoplasm EcoCyc:EG10360-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A6M8-1 20100331 PRO:CNA PR:000036690 large ribosomal subunit protein uL10 isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-rplJ/iso:1/InitMet-|PRO_0000154627|UniProtKB:P0A7J3-1, 2-165 part_of GO:0022625 cytosolic large ribosomal subunit EcoCyc:EG10871-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A7J3-1 20100331 PRO:CNA PR:000036694 small ribosomal subunit protein bS6 isoform 1 (Escherichia coli K-12) Ec-rpsF/iso:1|PRO_0000030641|UniProtKB:P02358-1, 1-131 enables GO:0003735 structural constituent of ribosome EcoCyc:EG10905-MONOMER EXP NCBITaxon:83333 UniProtKB:P02358-1 20100331 PRO:CNA PR:000036694 small ribosomal subunit protein bS6 isoform 1 (Escherichia coli K-12) Ec-rpsF/iso:1|PRO_0000030641|UniProtKB:P02358-1, 1-131 part_of GO:0022627 cytosolic small ribosomal subunit EcoCyc:EG10905-MONOMER EXP NCBITaxon:83333 UniProtKB:P02358-1 20100331 PRO:CNA PR:000036694 small ribosomal subunit protein bS6 isoform 1 (Escherichia coli K-12) Ec-rpsF/iso:1|PRO_0000030641|UniProtKB:P02358-1, 1-131 acts_upstream_of_or_within GO:0006412 translation EcoCyc:EG10905-MONOMER EXP NCBITaxon:83333 UniProtKB:P02358-1 20100331 PRO:CNA PR:000036699 transcriptional regulatory protein DpiA isoform 1 phosphorylated 1 (Escherichia coli K-12) DpiA-Pasp DNA-binding transcriptional dual regulator|DpiA-Pasp57|Ec-dpiA/iso:1/Phos:1|UniProtKB:P0AEF4-1, Asp-57, MOD:00042 enables GO:0000156 phosphorelay response regulator activity EcoCyc:PHOSPHO-DPIA EXP NCBITaxon:83333 UniProtKB:P0AEF4-1 20100331 PRO:CNA PR:000036699 transcriptional regulatory protein DpiA isoform 1 phosphorylated 1 (Escherichia coli K-12) DpiA-Pasp DNA-binding transcriptional dual regulator|DpiA-Pasp57|Ec-dpiA/iso:1/Phos:1|UniProtKB:P0AEF4-1, Asp-57, MOD:00042 enables GO:0003677 DNA binding EcoCyc:PHOSPHO-DPIA EXP NCBITaxon:83333 UniProtKB:P0AEF4-1 20100331 PRO:CNA PR:000036699 transcriptional regulatory protein DpiA isoform 1 phosphorylated 1 (Escherichia coli K-12) DpiA-Pasp DNA-binding transcriptional dual regulator|DpiA-Pasp57|Ec-dpiA/iso:1/Phos:1|UniProtKB:P0AEF4-1, Asp-57, MOD:00042 acts_upstream_of_or_within GO:0000160 phosphorelay signal transduction system EcoCyc:PHOSPHO-DPIA EXP NCBITaxon:83333 UniProtKB:P0AEF4-1 20100331 PRO:CNA PR:000036699 transcriptional regulatory protein DpiA isoform 1 phosphorylated 1 (Escherichia coli K-12) DpiA-Pasp DNA-binding transcriptional dual regulator|DpiA-Pasp57|Ec-dpiA/iso:1/Phos:1|UniProtKB:P0AEF4-1, Asp-57, MOD:00042 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription EcoCyc:PHOSPHO-DPIA EXP NCBITaxon:83333 UniProtKB:P0AEF4-1 20100331 PRO:CNA PR:000036713 fructose-bisphosphate aldolase class 2 isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-fbaA/iso:1/InitMet-|PRO_0000178713|UniProtKB:P0AB71-1, 2-359 enables GO:0004332 fructose-bisphosphate aldolase activity EcoCyc:FRUCTBISALD-CLASSII-MONOMER EXP NCBITaxon:83333 UniProtKB:P0AB71-1 20100331 PRO:CNA PR:000036713 fructose-bisphosphate aldolase class 2 isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-fbaA/iso:1/InitMet-|PRO_0000178713|UniProtKB:P0AB71-1, 2-359 enables GO:0008270 zinc ion binding EcoCyc:FRUCTBISALD-CLASSII-MONOMER EXP NCBITaxon:83333 UniProtKB:P0AB71-1 20100331 PRO:CNA PR:000036713 fructose-bisphosphate aldolase class 2 isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-fbaA/iso:1/InitMet-|PRO_0000178713|UniProtKB:P0AB71-1, 2-359 acts_upstream_of_or_within GO:0016052 carbohydrate catabolic process EcoCyc:FRUCTBISALD-CLASSII-MONOMER EXP NCBITaxon:83333 UniProtKB:P0AB71-1 20100331 PRO:CNA PR:000036716 sensor kinase dpiB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dpiB/iso:1/Phos:1|UniProtKB:P77510-1, His-347, MOD:00890 enables GO:0000155 phosphorelay sensor kinase activity EcoCyc:PHOSPHO-DPIB EXP NCBITaxon:83333 UniProtKB:P77510-1 20100331 PRO:CNA PR:000036716 sensor kinase dpiB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dpiB/iso:1/Phos:1|UniProtKB:P77510-1, His-347, MOD:00890 acts_upstream_of_or_within GO:0000160 phosphorelay signal transduction system EcoCyc:PHOSPHO-DPIB EXP NCBITaxon:83333 UniProtKB:P77510-1 20100331 PRO:CNA PR:000036716 sensor kinase dpiB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dpiB/iso:1/Phos:1|UniProtKB:P77510-1, His-347, MOD:00890 acts_upstream_of_or_within GO:0018106 peptidyl-histidine phosphorylation EcoCyc:PHOSPHO-DPIB EXP NCBITaxon:83333 UniProtKB:P77510-1 20100331 PRO:CNA PR:000036716 sensor kinase dpiB isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dpiB/iso:1/Phos:1|UniProtKB:P77510-1, His-347, MOD:00890 acts_upstream_of_or_within GO:0032101 regulation of response to external stimulus EcoCyc:PHOSPHO-DPIB EXP NCBITaxon:83333 UniProtKB:P77510-1 20100331 PRO:CNA PR:000036719 tyrosine-protein kinase wzc isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-wzc/iso:1/Phos:1|UniProtKB:P76387-1, Tyr-569, MOD:00048 increased enables GO:0004713 protein tyrosine kinase activity PR:000025097 PMID:11751920 EXP NCBITaxon:83333 UniProtKB:P76387-1 20100331 PRO:CNA PR:000036731 isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-icd/iso:1/Phos:1|UniProtKB:P08200-1, Ser-113, MOD:00046 acts_upstream_of_or_within GO:0006099 tricarboxylic acid cycle EcoCyc:ISOCITHASE-P EXP NCBITaxon:83333 UniProtKB:P08200-1 20100331 PRO:CNA PR:000036732 lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-lysU/iso:1/InitMet-|PRO_0000152627|UniProtKB:P0A8N5-1, 2-505 enables GO:0000287 magnesium ion binding EcoCyc:LYSU-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A8N5-1 20100331 PRO:CNA PR:000036732 lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-lysU/iso:1/InitMet-|PRO_0000152627|UniProtKB:P0A8N5-1, 2-505 enables GO:0004824 lysine-tRNA ligase activity EcoCyc:LYSU-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A8N5-1 20100331 PRO:CNA PR:000036732 lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-lysU/iso:1/InitMet-|PRO_0000152627|UniProtKB:P0A8N5-1, 2-505 enables GO:0005524 ATP binding EcoCyc:LYSU-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A8N5-1 20100331 PRO:CNA PR:000036732 lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-lysU/iso:1/InitMet-|PRO_0000152627|UniProtKB:P0A8N5-1, 2-505 acts_upstream_of_or_within GO:0006412 translation EcoCyc:LYSU-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A8N5-1 20100331 PRO:CNA PR:000036732 lysine--tRNA ligase, heat inducible isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-lysU/iso:1/InitMet-|PRO_0000152627|UniProtKB:P0A8N5-1, 2-505 acts_upstream_of_or_within GO:0006430 lysyl-tRNA aminoacylation EcoCyc:LYSU-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A8N5-1 20100331 PRO:CNA PR:000036738 nucleoside diphosphate kinase isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-ndk/iso:1/InitMet-|PRO_0000136978|UniProtKB:P0A763-1, 2-143 acts_upstream_of_or_within GO:0009152 purine ribonucleotide biosynthetic process EcoCyc:NUCLEOSIDE-DIP-KIN-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A763-1 20100331 PRO:CNA PR:000036738 nucleoside diphosphate kinase isoform 1, initiator methionine removed form (Escherichia coli K-12) Ec-ndk/iso:1/InitMet-|PRO_0000136978|UniProtKB:P0A763-1, 2-143 acts_upstream_of_or_within GO:0015949 nucleobase-containing small molecule interconversion EcoCyc:NUCLEOSIDE-DIP-KIN-MONOMER EXP NCBITaxon:83333 UniProtKB:P0A763-1 20100331 PRO:CNA PR:000036762 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 3 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:3|UniProtKB:P0AEC3-1, Asp-576, MOD:00042 enables GO:0000155 phosphorelay sensor kinase activity EcoCyc:PHOSPHO-ARCB-ASP EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036762 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 3 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:3|UniProtKB:P0AEC3-1, Asp-576, MOD:00042 located_in GO:0016020 membrane EcoCyc:PHOSPHO-ARCB-ASP EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036762 aerobic respiration control sensor protein ArcB isoform 1 phosphorylated 3 (Escherichia coli K-12) Ec-arcB/iso:1/Phos:3|UniProtKB:P0AEC3-1, Asp-576, MOD:00042 acts_upstream_of_or_within GO:0000160 phosphorelay signal transduction system EcoCyc:PHOSPHO-ARCB-ASP EXP NCBITaxon:83333 UniProtKB:P0AEC3-1 20100331 PRO:CNA PR:000036764 transcriptional regulatory protein DcuR isoform 1 phosphorylated 1 (Escherichia coli K-12) Ec-dcuR/iso:1/Phos:1|UniProtKB:P0AD01-1, Asp-56, MOD:00042 acts_upstream_of_or_within GO:0009061 anaerobic respiration EcoCyc:PHOSPHO-DCUR-MONOMER EXP NCBITaxon:83333 UniProtKB:P0AD01-1 20100331 PRO:CNA PR:000036781 periplasmic protein TorT isoform 1, signal peptide removed form (Escherichia coli K-12) Ec-torT/iso:1/SigPep-|PRO_0000031736|UniProtKB:P38683-1, 19-342 enables GO:0005488 binding CHEBI:15724 PMID:17040909 IDA NCBITaxon:83333 UniProtKB:P38683-1 20100510 PRO:CNA PR:000036781 periplasmic protein TorT isoform 1, signal peptide removed form (Escherichia coli K-12) Ec-torT/iso:1/SigPep-|PRO_0000031736|UniProtKB:P38683-1, 19-342 enables GO:0005515 protein binding PR:000025230 PMID:17040909 IPI NCBITaxon:83333 UniProtKB:P38683-1 20100510 PRO:CNA PR:000036781 periplasmic protein TorT isoform 1, signal peptide removed form (Escherichia coli K-12) Ec-torT/iso:1/SigPep-|PRO_0000031736|UniProtKB:P38683-1, 19-342 located_in GO:0042597 periplasmic space PMID:17040909|PMID:8576063 EXP NCBITaxon:83333 UniProtKB:P38683-1 20100510 PRO:CNA PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human) FASLG isoform 1 sequence variant 1 (human)|FASLG isoform FasL sequence variant 1 (human)|gld|hFASLG/iso:FasL/var:F273L|tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human)|tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human)|UniProtKB:P48023-1, Phe-275, CHEBI:30006 enables GO:0042802 identical protein binding PR:000000278 PMID:9405425 IPI NCBITaxon:9606 UniProtKB:P48023-1:L(275) 20080301 PRO:CNA Note=This variant is naturally found in mice, the annotation here is for the equivalent human form. PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human) FASLG isoform 1 sequence variant 1 (human)|FASLG isoform FasL sequence variant 1 (human)|gld|hFASLG/iso:FasL/var:F273L|tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human)|tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human)|UniProtKB:P48023-1, Phe-275, CHEBI:30006 located_in GO:0009986 cell surface PMID:9405425 IDA NCBITaxon:9606 UniProtKB:P48023-1:L(275) 20080301 PRO:CNA PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human) FASLG isoform 1 sequence variant 1 (human)|FASLG isoform FasL sequence variant 1 (human)|gld|hFASLG/iso:FasL/var:F273L|tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human)|tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human)|UniProtKB:P48023-1, Phe-275, CHEBI:30006 altered enables GO:0005102 signaling receptor binding PR:000036458 PR:P25445 PMID:9405425 IPI NCBITaxon:9606 UniProtKB:P48023-1:L(275) 20080301 PRO:CNA Note=This variant is naturally found in mice, the annotation here is for the equivalent human form. PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse) Faslg isoform 1 sequence variant 1 (mouse)|Faslg isoform FasL sequence variant 1 (mouse)|gld|mFASLG/iso:FasL/var:F273L|tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (mouse)|tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (mouse)|UniProtKB:P41047-1, Phe-273, CHEBI:30006 associated_with_disease_progression DOID:6688 autoimmune lymphoproliferative syndrome PMID:7495745 EXP NCBITaxon:10090 UniProtKB:P41047-1:L(273) 20080301 PRO:CNA PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse) Faslg isoform 1 sequence variant 1 (mouse)|Faslg isoform FasL sequence variant 1 (mouse)|gld|mFASLG/iso:FasL/var:F273L|tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (mouse)|tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (mouse)|UniProtKB:P41047-1, Phe-273, CHEBI:30006 located_in GO:0005886 plasma membrane PMID:7495745 IDA NCBITaxon:10090 UniProtKB:P41047-1:L(273) 20080301 PRO:CNA PR:000036829 NS2B-NS3 complex DenV-NS2BNS3|NS2B-NS3 protease|NS2B-NS3 protease complex|NS2B-NS3pro enables GO:0008236 serine-type peptidase activity PMID:10744671 EXP NCBITaxon:11065 20130711 PRO:ES PR:000036829 NS2B-NS3 complex DenV-NS2BNS3|NS2B-NS3 protease|NS2B-NS3 protease complex|NS2B-NS3pro enables GO:0008236 serine-type peptidase activity PMID:23511634 EXP NCBITaxon:11060 20130711 PRO:ES Note=Likely strain: TSV01 (traced from acknowledgements); no TaxId for that strain PR:000036829 NS2B-NS3 complex DenV-NS2BNS3|NS2B-NS3 protease|NS2B-NS3 protease complex|NS2B-NS3pro acts_upstream_of_or_within GO:0016540 protein autoprocessing PMID:23511634 EXP NCBITaxon:11060 20130711 PRO:ES Note=Likely strain: TSV01 (traced from acknowledgements); no TaxId for that strain PR:000036829 NS2B-NS3 complex DenV-NS2BNS3|NS2B-NS3 protease|NS2B-NS3 protease complex|NS2B-NS3pro acts_upstream_of_or_within GO:0019082 viral protein processing PMID:10744671 EXP NCBITaxon:11065 20130711 PRO:ES PR:000036829 NS2B-NS3 complex DenV-NS2BNS3|NS2B-NS3 protease|NS2B-NS3 protease complex|NS2B-NS3pro acts_upstream_of_or_within GO:0019082 viral protein processing PMID:23511634 EXP NCBITaxon:11060 20130711 PRO:ES Note=Likely strain: TSV01 (traced from acknowledgements); no TaxId for that strain PR:000036846 class II olfactory receptor fam:OR[II] located_in GO:0005737 cytoplasm MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:000036848 CD14 molecule cleaved 2 CD14/iso:1/Clv:2 located_in GO:0005737 cytoplasm MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:000036848 CD14 molecule cleaved 2 CD14/iso:1/Clv:2 located_in GO:0016020 membrane MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:000036848 CD14 molecule cleaved 2 CD14/iso:1/Clv:2 acts_upstream_of_or_within GO:0032147 activation of protein kinase activity MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI regulates_o_occurs_in(MA:0000411) PR:000036858 presenilin-2 isoform PS2short (mouse) mPSEN2/iso:PS2short|PS2s|UniProtKB:Q61144-1, 298-448 acts_upstream_of_or_within GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors MGI_ref:1099227|PMID:9353287 IDA NCBITaxon:10090 MGI:109284 20130620 MGI:MGI PR:000036860 catenin beta-1 phosphorylated 1 (mouse) mCTNNB1/Phos:1|UniProtKB:Q02248, Tyr-142, MOD:00048 decreased enables GO:0045296 cadherin binding PR:000037183 PMID:12640114 EXP NCBITaxon:10090 UniProtKB:Q02248 20130711 PRO:IC PR:000036862 catenin beta-1 isoform 1 phosphorylated 5 (human) hCTNNB1/iso:1/Phos:5|UniProtKB:P35222-1, Ser-552/Ser-675, MOD:00046 increased enables GO:0003713 transcription coactivator activity PR:000036872 PMID:16476742 EXP NCBITaxon:9606 UniProtKB:P35222-1 20130711 PRO:IC PR:000036862 catenin beta-1 isoform 1 phosphorylated 5 (human) hCTNNB1/iso:1/Phos:5|UniProtKB:P35222-1, Ser-552/Ser-675, MOD:00046 increased enables GO:0005515 protein binding PR:000036872 PR:Q92793 PMID:16476742 IPI NCBITaxon:9606 UniProtKB:P35222-1 20130711 PRO:IC PR:000036893 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 1 (mouse) LKB1 tyrosine phosphorylated|mSTK11/iso:1/Phos:1|UniProtKB:Q9WTK7-1, Tyr-261/Tyr-365, MOD:00048 located_in GO:0005634 nucleus MGI_ref:4439241|PMID:20142099 IDA NCBITaxon:10090 MGI:1341870 20130715 MGI:MGI part_of(CL:0000056) PR:000036932 smad7 isoform 1 phosphorylated 1 (mouse) mSMAD7/iso:1/Phos:1|UniProtKB:O35253-1, Ser-249, MOD:00046 enables GO:0140416 transcription regulator inhibitor activity PMID:11278814 IDA NCBITaxon:10090 UniProtKB:O35253-1 20080301 PRO:CNA PR:000036932 smad7 isoform 1 phosphorylated 1 (mouse) mSMAD7/iso:1/Phos:1|UniProtKB:O35253-1, Ser-249, MOD:00046 located_in GO:0005634 nucleus PMID:11278814 IDA NCBITaxon:10090 UniProtKB:O35253-1 20080301 PRO:CNA PR:000036932 smad7 isoform 1 phosphorylated 1 (mouse) mSMAD7/iso:1/Phos:1|UniProtKB:O35253-1, Ser-249, MOD:00046 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11278814 IDA NCBITaxon:10090 UniProtKB:O35253-1 20080301 PRO:CNA PR:000036990 amyloid-beta precursor protein sequence variant I716M (human) hAPP/var:I716M|UniProtKB:P05067-1, Ile-716, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-i716m EXP NCBITaxon:9606 Alzforum:app-i716m 20180510 PRO:DAN PR:000036991 amyloid-beta precursor protein sequence variant M722K (human) hAPP/var:M722K|UniProtKB:P05067-1, Met-722, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-m722k EXP NCBITaxon:9606 Alzforum:app-m722k 20180510 PRO:DAN PR:000036993 microtubule-associated protein tau sequence variant Q336H (human) hMAPT/var:Q336H|UniProtKB:P10636-8, Gln-336, CHEBI:29979 associated_with_disease_progression DOID:11870 Pick's disease Alzforum:mapt-q336h EXP NCBITaxon:9606 Alzforum:mapt-q336h 20180510 PRO:DAN PR:000036994 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 STK11/iso:1/Phos:2 part_of GO:0036398 TCR signalosome MGI_ref:5003385|PMID:21487392 IDA NCBITaxon:10090 MGI:1341870 20130722 MGI:MGI part_of(CL:0000809)|part_of(CL:0000809) PR:000036994 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 STK11/iso:1/Phos:2 acts_upstream_of_or_within GO:0036399 TCR signalosome assembly MGI_ref:5003385|PMID:21487392 IMP NCBITaxon:10090 MGI_allele:2387402|MGI_allele:3054844 MGI:1341870 20130722 MGI:MGI occurs_in(CL:0000809)|occurs_in(CL:0000809) PR:000036994 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 STK11/iso:1/Phos:2 acts_upstream_of_or_within GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:5003385|PMID:21487392 IMP NCBITaxon:10090 MGI_allele:2387402|MGI_allele:3054844 MGI:1341870 20130716 MGI:MGI PR:000036995 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 (mouse) LKB1(L) tyrosine phosphorylated|mSTK11/iso:1/Phos:2|UniProtKB:Q9WTK7-1, Tyr-36/Tyr-261/Tyr-365, MOD:00048 part_of GO:0036398 TCR signalosome MGI_ref:5003385|PMID:21487392 IDA NCBITaxon:10090 MGI:1341870 20130722 MGI:MGI part_of(CL:0000809)|part_of(CL:0000809) PR:000036995 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 (mouse) LKB1(L) tyrosine phosphorylated|mSTK11/iso:1/Phos:2|UniProtKB:Q9WTK7-1, Tyr-36/Tyr-261/Tyr-365, MOD:00048 acts_upstream_of_or_within GO:0036399 TCR signalosome assembly MGI_ref:5003385|PMID:21487392 IMP NCBITaxon:10090 MGI_allele:2387402|MGI_allele:3054844 MGI:1341870 20130722 MGI:MGI occurs_in(CL:0000809)|occurs_in(CL:0000809) PR:000036995 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 (mouse) LKB1(L) tyrosine phosphorylated|mSTK11/iso:1/Phos:2|UniProtKB:Q9WTK7-1, Tyr-36/Tyr-261/Tyr-365, MOD:00048 acts_upstream_of_or_within GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:5003385|PMID:21487392 IMP NCBITaxon:10090 MGI_allele:2387402|MGI_allele:3054844 MGI:1341870 20130716 MGI:MGI PR:000036997 serine/threonine-protein kinase STK11 isoform 1 unphosphorylated 1 (mouse) mSTK11/iso:1/UnPhos:1|UniProtKB:Q9WTK7-1, Tyr-261/Tyr-365, PR:000026291 located_in GO:0005737 cytoplasm MGI_ref:4439241|PMID:20142099 IMP NCBITaxon:10090 MGI:1341870 20130715 MGI:MGI PR:000036999 E protein dimer enables GO:0046789 host cell surface receptor binding PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000036999 E protein dimer located_in GO:0019031 viral envelope PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000036999 E protein dimer acts_upstream_of_or_within GO:0019064 fusion of virus membrane with host plasma membrane PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000037002 NS1 dimer part_of GO:0019034 viral replication complex PMID:8659120 EXP NCBITaxon:11065 20130711 PRO:ES PR:000037002 NS1 dimer acts_upstream_of_or_within GO:0019079 viral genome replication PMID:8659120 EXP NCBITaxon:11065 20130711 PRO:ES PR:000037002 NS1 dimer acts_upstream_of_or_within GO:0097281 immune complex formation PMID:8659120 EXP NCBITaxon:11065 20130711 PRO:ES PR:000037005 NS1 hexamer, with complex sugar attached located_in GO:0005615 extracellular space PMID:8659120 EXP NCBITaxon:11065 20130711 PRO:ES PR:000037051 POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 (mouse) mPOU5F1/iso:1/Phos:1|UniProtKB:P20263-1, Thr-228, MOD:00047 acts_upstream_of_or_within GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5490149|PMID:23495099 IMP NCBITaxon:10090 MGI:101893 20140910 MGI:MGI PR:000037067 carcinoembryonic antigen-related cell adhesion molecule 10, cleaved and N-glycosylated (mouse) Ceacam10 glycosylated|mCeacam10/ClvNGlyco[1/2/3] located_in GO:0005576 extracellular region MGI_ref:5504399|PMID:15901639 IDA NCBITaxon:10090 MGI:1347248 20130904 MGI:MGI part_of(MA:0000410),part_of(CL:1001597) PR:000037067 carcinoembryonic antigen-related cell adhesion molecule 10, cleaved and N-glycosylated (mouse) Ceacam10 glycosylated|mCeacam10/ClvNGlyco[1/2/3] acts_upstream_of_or_within GO:0030317 flagellated sperm motility MGI_ref:5504399|PMID:15901639 IDA NCBITaxon:10090 MGI:1347248 20130904 MGI:MGI PR:000037136 cathepsin L short form (mouse) cytosolic CatL|mCtsl/iso:[2/3/4/5/6/7]|Short-form CatL located_in GO:0005634 nucleus MGI_ref:3044037|PMID:15099520 IDA NCBITaxon:10090 MGI:88564 20131014 MGI:MGI PR:000037136 cathepsin L short form (mouse) cytosolic CatL|mCtsl/iso:[2/3/4/5/6/7]|Short-form CatL located_in GO:0005634 nucleus MGI_ref:5297732|PMID:21911934 IDA NCBITaxon:10090 MGI:88564 20131017 MGI:MGI PR:000037136 cathepsin L short form (mouse) cytosolic CatL|mCtsl/iso:[2/3/4/5/6/7]|Short-form CatL acts_upstream_of_or_within GO:0016485 protein processing MGI_ref:3044037|PMID:15099520 IDA NCBITaxon:10090 MGI:88564 20131014 MGI:MGI PR:000037136 cathepsin L short form (mouse) cytosolic CatL|mCtsl/iso:[2/3/4/5/6/7]|Short-form CatL acts_upstream_of_or_within GO:0016485 protein processing MGI_ref:3044037|PMID:15099520 IMP NCBITaxon:10090 MGI_allele:2136432 MGI:88564 20131014 MGI:MGI PR:000037136 cathepsin L short form (mouse) cytosolic CatL|mCtsl/iso:[2/3/4/5/6/7]|Short-form CatL acts_upstream_of_or_within GO:0032956 regulation of actin cytoskeleton organization MGI_ref:5297732|PMID:21911934 IGI NCBITaxon:10090 MGI:1330281|MGI:98725 MGI:88564 20131014 MGI:MGI regulates_o_occurs_in(CL:0000653) PR:000037167 C-C motif chemokine 27 isoform 1, signal peptide removed form (mouse) mCCL27/iso:1/SigPep-|PRO_0000005240|UniProtKB:Q9Z1X0-1, 26-120 located_in GO:0005576 extracellular region MGI_ref:1347714|PMID:10559234 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI PR:000037167 C-C motif chemokine 27 isoform 1, signal peptide removed form (mouse) mCCL27/iso:1/SigPep-|PRO_0000005240|UniProtKB:Q9Z1X0-1, 26-120 acts_upstream_of_or_within GO:0071677 positive regulation of mononuclear cell migration MGI_ref:1347714|PMID:10559234 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI regulates_o_results_in_movement_of(CL:0000842) PR:000037167 C-C motif chemokine 27 isoform 1, signal peptide removed form (mouse) mCCL27/iso:1/SigPep-|PRO_0000005240|UniProtKB:Q9Z1X0-1, 26-120 NOT located_in GO:0005634 nucleus MGI_ref:1347714|PMID:10559234 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI PR:000037181 catenin beta-1 isoform 1 phosphorylated 6 (human) hCTNNB1/iso:1/Phos:6|UniProtKB:P35222-1, Ser-37, MOD:00046|Thr-41, MOD:00047 decreased located_in GO:0005912 adherens junction PR:000037185 PMID:19667122 EXP NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037185 catenin beta-1 isoform 1 unphosphorylated 2 (human) hCTNNB1/iso:1/UnPhos:2|UniProtKB:P35222-1, Ser-37/Thr-41, PR:000026291 enables GO:0003713 transcription coactivator activity PMID:20419129 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037185 catenin beta-1 isoform 1 unphosphorylated 2 (human) hCTNNB1/iso:1/UnPhos:2|UniProtKB:P35222-1, Ser-37/Thr-41, PR:000026291 enables GO:0005515 protein binding PR:P12830 PMID:20419129 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037185 catenin beta-1 isoform 1 unphosphorylated 2 (human) hCTNNB1/iso:1/UnPhos:2|UniProtKB:P35222-1, Ser-37/Thr-41, PR:000026291 located_in GO:0005634 nucleus PMID:20419129 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037187 catenin beta-1 phosphorylated 2 (mouse) mCTNNB1/Phos:2|UniProtKB:Q02248, Ser-29, MOD:00046|Thr-102/Thr-112, MOD:00047 enables GO:0045294 alpha-catenin binding PMID:12432063 EXP NCBITaxon:10090 UniProtKB:Q02248 20131030 PRO:IC PR:000037187 catenin beta-1 phosphorylated 2 (mouse) mCTNNB1/Phos:2|UniProtKB:Q02248, Ser-29, MOD:00046|Thr-102/Thr-112, MOD:00047 located_in GO:0005912 adherens junction PMID:12432063 EXP NCBITaxon:10090 UniProtKB:Q02248 20131030 PRO:IC PR:000037187 catenin beta-1 phosphorylated 2 (mouse) mCTNNB1/Phos:2|UniProtKB:Q02248, Ser-29, MOD:00046|Thr-102/Thr-112, MOD:00047 increased enables GO:0019901 protein kinase binding PR:000037185 PR:Q9WV60 PMID:12432063 IPI NCBITaxon:10090 UniProtKB:Q02248 20131030 PRO:IC PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 located_in GO:0005737 cytoplasm PMID:20419129 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 acts_upstream_of_or_within GO:0010631 epithelial cell migration PMID:21152425 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased enables GO:0003713 transcription coactivator activity PR:000037185 PMID:20419129 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased enables GO:0005515 protein binding PR:000037811 PR:P36402 PMID:23617586 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased enables GO:0005515 protein binding PR:000037811 PR:Q9HCS4 PMID:23617586 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased enables GO:0005515 protein binding PR:000037811 PR:Q9NQB0 PMID:23617586 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased enables GO:0005515 protein binding PR:000037811 PR:Q9UJU2 PMID:23617586 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased located_in GO:0005912 adherens junction PR:000037811 PMID:19667122 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased acts_upstream_of_or_within GO:0007155 cell adhesion PR:000037811 PMID:19667122 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 decreased acts_upstream_of_or_within GO:0034333 adherens junction assembly PR:000037811 PMID:19667122 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 increased enables GO:0005515 protein binding PR:000037811 PR:Q9Y297 PMID:21152425 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037190 catenin beta-1 isoform 1 phosphorylated 7 (human) hCTNNB1/iso:1/Phos:7|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047 NOT enables GO:0005515 protein binding PR:P12830 PMID:21152425 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140903 PRO:KER PR:000037192 catenin beta-1 isoform 1 phosphorylated 8 (human) hCTNNB1/iso:1/Phos:8|UniProtKB:P35222-1, Tyr-333, MOD:00048 enables GO:0003713 transcription coactivator activity PMID:22056988 EXP NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER PR:000037192 catenin beta-1 isoform 1 phosphorylated 8 (human) hCTNNB1/iso:1/Phos:8|UniProtKB:P35222-1, Tyr-333, MOD:00048 enables GO:0005515 protein binding PR:P14618 PMID:22056988 IPI NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037192 catenin beta-1 isoform 1 phosphorylated 8 (human) hCTNNB1/iso:1/Phos:8|UniProtKB:P35222-1, Tyr-333, MOD:00048 located_in GO:0005634 nucleus PMID:22056988 EXP NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037192 catenin beta-1 isoform 1 phosphorylated 8 (human) hCTNNB1/iso:1/Phos:8|UniProtKB:P35222-1, Tyr-333, MOD:00048 acts_upstream_of_or_within GO:0007173 epidermal growth factor receptor signaling pathway PMID:22056988 EXP NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037194 catenin beta-1 isoform 1 phosphorylated 9 (human) hCTNNB1/iso:1/Phos:9|UniProtKB:P35222-1, Tyr-86/Tyr-654, MOD:00048 decreased enables GO:0045296 cadherin binding PR:000037196 PR:P12830 PMID:11279024 IPI NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037194 catenin beta-1 isoform 1 phosphorylated 9 (human) hCTNNB1/iso:1/Phos:9|UniProtKB:P35222-1, Tyr-86/Tyr-654, MOD:00048 increased enables GO:0017025 TBP-class protein binding PR:000037196 PR:P20226 PMID:11279024 IPI NCBITaxon:9606 UniProtKB:P35222-1 20131030 PRO:IC PR:000037245 chymotrypsin-like elastase family member 2A, mature form (mouse) Cela2a (mouse)|Ela2 (mouse)|elastase 2 (mouse)|mCELA2A/mature|PRO_0000027688|UniProtKB:P05208, 31-271 enables GO:0017171 serine hydrolase activity MGI_ref:4440399|PMID:20179351 IDA NCBITaxon:10090 MGI:95316 20131210 MGI:MGI occurs_in(MA:0000153) PR:000037245 chymotrypsin-like elastase family member 2A, mature form (mouse) Cela2a (mouse)|Ela2 (mouse)|elastase 2 (mouse)|mCELA2A/mature|PRO_0000027688|UniProtKB:P05208, 31-271 enables GO:0017171 serine hydrolase activity MGI_ref:4440399|PMID:20179351 IMP NCBITaxon:10090 MGI_allele:5523057 MGI:95316 20131210 MGI:MGI occurs_in(MA:0000153) PR:000037245 chymotrypsin-like elastase family member 2A, mature form (mouse) Cela2a (mouse)|Ela2 (mouse)|elastase 2 (mouse)|mCELA2A/mature|PRO_0000027688|UniProtKB:P05208, 31-271 acts_upstream_of_or_within GO:0006508 proteolysis MGI_ref:4440399|PMID:20179351 IMP NCBITaxon:10090 MGI_allele:5523057 MGI:95316 20131210 MGI:MGI occurs_in(MA:0000153) PR:000037245 chymotrypsin-like elastase family member 2A, mature form (mouse) Cela2a (mouse)|Ela2 (mouse)|elastase 2 (mouse)|mCELA2A/mature|PRO_0000027688|UniProtKB:P05208, 31-271 acts_upstream_of_or_within GO:0061436 establishment of skin barrier MGI_ref:4440399|PMID:20179351 IMP NCBITaxon:10090 MGI_allele:5523057 MGI:95316 20131210 MGI:MGI has_participant(MA:0000153) PR:000037260 cochlin, signal peptide removed form (mouse) mCOCH/SigPep-|UniProtKB:Q62507, 26-552 located_in GO:0031012 extracellular matrix MGI_ref:5525040|PMID:23684986 IDA NCBITaxon:10090 MGI:1278313 20140106 MGI:MGI part_of(MA:0000141),part_of(CL:0000442) PR:000037261 cochlin p8 (mouse) mCOCH/Clv:p8|N-terminal fragment (mouse)|UniProtKB:Q62507, 26-134 located_in GO:0005576 extracellular region MGI_ref:5525040|PMID:23684986 IMP NCBITaxon:10090 MGI_allele:3624560 MGI:1278313 20140214 MGI:MGI part_of(MA:0000059) PR:000037262 cochlin p18 (mouse) mCOCH/Clv:p18|N-terminal fragment glycosylated (mouse)|UniProtKB:Q62507, 26-134, MOD:00693 located_in GO:0005576 extracellular region MGI_ref:5525040|PMID:23684986 IMP NCBITaxon:10090 MGI_allele:3624560 MGI:1278313 20140107 MGI:MGI part_of(MA:0000059) PR:000037263 cochlin p40 (mouse) cochlin C-terminal fragment (mouse)|mCOCH/Clv:p40|UniProtKB:Q62507, 135-552 located_in GO:0031012 extracellular matrix MGI_ref:5525040|PMID:23684986 IDA NCBITaxon:10090 MGI:1278313 20140214 MGI:MGI part_of(MA:0000141),part_of(CL:0000442) PR:000037266 cochlin N-terminal fragment (mouse) mCOCH/Nter acts_upstream_of_or_within GO:0042742 defense response to bacterium MGI_ref:5525040|PMID:23684986 IMP NCBITaxon:10090 MGI_allele:3624560 MGI:1278313 20140107 MGI:MGI PR:000037266 cochlin N-terminal fragment (mouse) mCOCH/Nter acts_upstream_of_or_within GO:0045089 positive regulation of innate immune response MGI_ref:5525040|PMID:23684986 IMP NCBITaxon:10090 MGI_allele:3624560 MGI:1278313 20140107 MGI:MGI PR:000037269 sonic hedgehog protein N-product dually lipidated 1 (mouse) mSHH/Clv:Nter/2*Lipid:1|UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314 acts_upstream_of_or_within GO:0007224 smoothened signaling pathway MGI_ref:3039193|PMID:15075292 IMP NCBITaxon:10090 MGI:98297 20140121 MGI:MGI occurs_in(EMAP:11204) PR:000037269 sonic hedgehog protein N-product dually lipidated 1 (mouse) mSHH/Clv:Nter/2*Lipid:1|UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314 acts_upstream_of_or_within GO:0009952 anterior/posterior pattern specification MGI_ref:2135419|PMID:11389830 IMP NCBITaxon:10090 MGI_allele:1934261|MGI_allele:2387802 MGI:98297 20140121 MGI:MGI has_output_o_axis_of(EMAP:11242),occurs_in(EMAP:11242)|has_output_o_axis_of(EMAP:11310),occurs_in(EMAP:11310) PR:000037269 sonic hedgehog protein N-product dually lipidated 1 (mouse) mSHH/Clv:Nter/2*Lipid:1|UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314 acts_upstream_of_or_within GO:0030326 embryonic limb morphogenesis MGI_ref:2135419|PMID:11389830 IMP NCBITaxon:10090 MGI_allele:1934261|MGI_allele:2387802 MGI:98297 20140121 MGI:MGI occurs_in(EMAP:11242)|occurs_in(EMAP:11310) PR:000037269 sonic hedgehog protein N-product dually lipidated 1 (mouse) mSHH/Clv:Nter/2*Lipid:1|UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314 acts_upstream_of_or_within GO:0042733 embryonic digit morphogenesis MGI_ref:3039193|PMID:15075292 IMP NCBITaxon:10090 MGI:98297 20140121 MGI:MGI occurs_in(EMAP:11204) PR:000037287 paired box protein Pax-6 isoform 3 sumoylated 1 (mouse) mPAX6/iso:3/Sumo:1|UniProtKB:P63015-3, Lys-91, MOD:01149 enables GO:0043565 sequence-specific DNA binding MGI_ref:4867351|PMID:21084637 IDA NCBITaxon:10090 MGI:97490 20140117 MGI:MGI PR:000037303 viral dsRNA:TLR3 complex (human) h(vir)dsRNA:TLR3 located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7159 20140224 PRO:VS PR:000037303 viral dsRNA:TLR3 complex (human) h(vir)dsRNA:TLR3 acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7159 20140226 PRO:VS PR:000037303 viral dsRNA:TLR3 complex (human) h(vir)dsRNA:TLR3 acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7159 20140224 PRO:VS PR:000037304 viral dsRNA:TLR3 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18420935 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037304 viral dsRNA:TLR3 complex (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:18420935 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037307 ticam1:viral dsRNA:TLR3 complex (human) viral dsRNA:TLR3:TRIF (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7381 20140224 PRO:VS PR:000037307 ticam1:viral dsRNA:TLR3 complex (human) viral dsRNA:TLR3:TRIF (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7381 20140226 PRO:VS PR:000037307 ticam1:viral dsRNA:TLR3 complex (human) viral dsRNA:TLR3:TRIF (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7381 20140224 PRO:VS PR:000037308 ticam1:viral dsRNA:TLR3 complex (mouse) TLR3TLR3dsRNATrif (mouse)|viral dsRNA:TLR3:TRIF (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:12539043 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037308 ticam1:viral dsRNA:TLR3 complex (mouse) TLR3TLR3dsRNATrif (mouse)|viral dsRNA:TLR3:TRIF (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12539043 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037310 traf3:ticam1:activated TLR3 complex (human) TRAF3:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124037 20140224 PRO:VS PR:000037310 traf3:ticam1:activated TLR3 complex (human) TRAF3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124037 20140226 PRO:VS PR:000037310 traf3:ticam1:activated TLR3 complex (human) TRAF3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124037 20140224 PRO:VS PR:000037311 traf3:ticam1:activated TLR3 complex (mouse) TLR3TLR3dsRNATriftraf3 (mouse)|TRAF3:TRIF:activated TLR3 (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:16306936|PMID:16306937 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse) TLR3TLR3dsRNATriftraf3TBK1tankIKKe (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12133833|PMID:17327220 EXP NCBITaxon:10090 20140224 TLR:AMM PR:000037315 K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124855 20140224 PRO:VS PR:000037315 K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124855 20140226 PRO:VS PR:000037315 K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_124855 20140224 PRO:VS PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140224 PRO:VS PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140226 PRO:VS PR:000037320 p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140224 PRO:VS PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140224 PRO:VS PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140226 PRO:VS PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26959 20140224 PRO:VS PR:000037330 SARM:ticam1:activated TLR3 complex (human) SARM:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151758 20140224 PRO:VS PR:000037330 SARM:ticam1:activated TLR3 complex (human) SARM:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151758 20140226 PRO:VS PR:000037330 SARM:ticam1:activated TLR3 complex (human) SARM:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151758 20140224 PRO:VS PR:000037332 rip3:ticam1:activated TLR3 complex (human) RIP3:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152149 20140224 PRO:VS PR:000037332 rip3:ticam1:activated TLR3 complex (human) RIP3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152149 20140226 PRO:VS PR:000037332 rip3:ticam1:activated TLR3 complex (human) RIP3:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152149 20140224 PRO:VS PR:000037334 rip1:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7715 20140224 PRO:VS PR:000037334 rip1:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7715 20140226 PRO:VS PR:000037334 rip1:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_7715 20140224 PRO:VS PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151344 20140224 PRO:VS PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151344 20140226 PRO:VS PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human) rip1:TRIF:activated TLR3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_151344 20140224 PRO:VS PR:000037338 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26039 20140224 PRO:VS PR:000037338 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26039 20140226 PRO:VS PR:000037338 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:activated TAK1 complex (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26039 20140224 PRO:VS PR:000037340 pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25867 20140224 PRO:VS PR:000037340 pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25867 20140226 PRO:VS PR:000037340 pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25867 20140224 PRO:VS PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26036 20140224 PRO:VS PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26036 20140226 PRO:VS PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-TRAF6:free K63-linked pUb:TAK1complex (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26036 20140224 PRO:VS PR:000037344 traf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR3 complex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25948 20140224 PRO:VS PR:000037344 traf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR3 complex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25948 20140226 PRO:VS PR:000037344 traf6:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:TRAF6 (human)|traf6:trif:tram:activated TLR3 complex (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25948 20140224 PRO:VS PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140226 PRO:VS PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF7 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF7 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140226 PRO:VS PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF7 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF3 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF3 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140226 PRO:VS PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF3 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF7 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF7 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140226 PRO:VS PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF7 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_27000 20140224 PRO:VS PR:000037362 K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25755 20140224 PRO:VS PR:000037362 K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25755 20140226 PRO:VS PR:000037362 K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_25755 20140224 PRO:VS PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1:IKKcomplex (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26016 20140224 PRO:VS PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1:IKKcomplex (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26016 20140226 PRO:VS PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:K63-pUb-RIP1:IKKcomplex (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_26016 20140224 PRO:VS PR:000037366 fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_150943 20140224 PRO:VS PR:000037366 fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_150943 20140226 PRO:VS PR:000037366 fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_150943 20140224 PRO:VS PR:000037368 pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 (human) located_in GO:0010008 endosome membrane Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152273 20140224 PRO:VS PR:000037368 pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152273 20140226 PRO:VS PR:000037368 pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human) activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 (human) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783 EXP NCBITaxon:9606 Reactome:REACT_152273 20140224 PRO:VS PR:000037374 ethylene-responsive transcription factor 1 phosphorylated 1 (rice) rice-EREBP1/Phos:1 increased enables GO:0003677 DNA binding PR:000037375 PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q6K7E6 20140402 PRO:LVM PR:000037375 ethylene-responsive transcription factor 1 unphosphorylated 1 (rice) rice-EREBP1/UnPhos:1 enables GO:0003677 DNA binding PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q6K7E6-1 20140402 PRO:LVM PR:000037379 ethylene-responsive transcription factor 6 phosphorylated 1 (Arabidopsis thaliana) At-ERF6/Phos:1|UniProtKB:Q8VZ91, Ser-266/Ser-269, MOD:00046 located_in GO:0005634 nucleus PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91-1 20140402 PRO:LVM PR:000037379 ethylene-responsive transcription factor 6 phosphorylated 1 (Arabidopsis thaliana) At-ERF6/Phos:1|UniProtKB:Q8VZ91, Ser-266/Ser-269, MOD:00046 increased acts_upstream_of_or_within GO:1900409 positive regulation of cellular response to oxidative stress PR:000037410 PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91-1 20140402 PRO:LVM PR:000037382 transcription factor MYB41 phosphorylated 1 (Arabidopsis thaliana) At-MYB41/Phos:1|UniProtKB:Q9M0J5, Ser-251, MOD:00046 enables GO:0003677 DNA binding PMID:22575450 EXP NCBITaxon:3702 UniProtKB:Q9M0J5-1 20140402 PRO:LVM PR:000037382 transcription factor MYB41 phosphorylated 1 (Arabidopsis thaliana) At-MYB41/Phos:1|UniProtKB:Q9M0J5, Ser-251, MOD:00046 acts_upstream_of_or_within GO:1901002 positive regulation of response to salt stress PMID:22575450 EXP NCBITaxon:3702 UniProtKB:Q9M0J5-1 20140402 PRO:LVM PR:000037387 MAPK kinase substrate protein At1g80180 phosphorylated 1 (Arabidopsis thaliana) At-At1g80180/Phos:1|UniProtKB:Q9SSC1, Ser-105, MOD:00046 increased acts_upstream_of_or_within GO:0045770 positive regulation of asymmetric cell division PR:000037411 PMID:22631074 EXP NCBITaxon:3702 UniProtKB:Q9SSC1-1 20140402 PRO:LVM PR:000037393 ceramide synthase isoform 1 FAM57B/iso:1 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation MGI_ref:4940967|PMID:19745830 IDA NCBITaxon:10090 MGI:109127 20110412 MGI:MGI PR:000037393 ceramide synthase isoform 1 FAM57B/iso:1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:4940967|PMID:19745830 IDA NCBITaxon:10090 MGI:109127 20110412 MGI:MGI PR:000037408 transcription factor SPEECHLESS phosphorylated 1 (Arabidopsis thaliana) At-SPCH/Phos:1|UniProtKB:Q700C7, Ser-193/Ser-211/Ser-219/Ser-255, MOD:00046|Thr-214, MOD:00047 located_in GO:0005634 nucleus PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7-1 20140402 PRO:LVM PR:000037408 transcription factor SPEECHLESS phosphorylated 1 (Arabidopsis thaliana) At-SPCH/Phos:1|UniProtKB:Q700C7, Ser-193/Ser-211/Ser-219/Ser-255, MOD:00046|Thr-214, MOD:00047 altered acts_upstream_of_or_within GO:2000037 regulation of stomatal complex patterning PR:000037409 PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7-1 20140402 PRO:LVM PR:000037408 transcription factor SPEECHLESS phosphorylated 1 (Arabidopsis thaliana) At-SPCH/Phos:1|UniProtKB:Q700C7, Ser-193/Ser-211/Ser-219/Ser-255, MOD:00046|Thr-214, MOD:00047 decreased acts_upstream_of_or_within GO:0045770 positive regulation of asymmetric cell division PR:000037409 PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7-1 20140402 PRO:LVM PR:000037409 transcription factor SPEECHLESS unphosphorylated 1 (Arabidopsis thaliana) At-SPCH/UnPhos:1|UniProtKB:Q700C7, Ser-193/Ser-211/Thr-214/Ser-219/Ser-255, PR:000026291 acts_upstream_of_or_within GO:0045770 positive regulation of asymmetric cell division PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7-1 20140402 PRO:LVM PR:000037409 transcription factor SPEECHLESS unphosphorylated 1 (Arabidopsis thaliana) At-SPCH/UnPhos:1|UniProtKB:Q700C7, Ser-193/Ser-211/Thr-214/Ser-219/Ser-255, PR:000026291 acts_upstream_of_or_within GO:2000037 regulation of stomatal complex patterning PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7-1 20140402 PRO:LVM PR:000037410 ethylene-responsive transcription factor 6 unphosphorylated 1 (Arabidopsis thaliana) At-ERF6/UnPhos:1|UniProtKB:Q8VZ91, Ser-266/Ser-269, PR:000026291 acts_upstream_of_or_within GO:1900409 positive regulation of cellular response to oxidative stress PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91-1 20140402 PRO:LVM PR:000037411 MAPK kinase substrate protein At1g80180 unphosphorylated 1 (Arabidopsis thaliana) At-At1g80180/UnPhos:1|UniProtKB:Q9SSC1, Ser-105, PR:000026291 acts_upstream_of_or_within GO:0045770 positive regulation of asymmetric cell division PMID:22631074 EXP NCBITaxon:3702 UniProtKB:Q9SSC1-1 20140402 PRO:LVM PR:000037415 mRNA-decapping enzyme-like protein phosphorylated 1 (Arabidopsis thaliana) At-DCP1A/Phos:1|phospho-DCP1|UniProtKB:Q9SJF3, Ser-237, MOD:00046 acts_upstream_of_or_within GO:1902584 positive regulation of response to water deprivation PMID:22407295 EXP NCBITaxon:3702 UniProtKB:Q9SJF3-1 20140403 PRO:LVM PR:000037415 mRNA-decapping enzyme-like protein phosphorylated 1 (Arabidopsis thaliana) At-DCP1A/Phos:1|phospho-DCP1|UniProtKB:Q9SJF3, Ser-237, MOD:00046 increased enables GO:0005515 protein binding PR:000037416 PR:Q9C658 PMID:22407295 IPI NCBITaxon:3702 UniProtKB:Q9SJF3-1 20140403 PRO:LVM PR:000037415 mRNA-decapping enzyme-like protein phosphorylated 1 (Arabidopsis thaliana) At-DCP1A/Phos:1|phospho-DCP1|UniProtKB:Q9SJF3, Ser-237, MOD:00046 increased acts_upstream_of_or_within GO:0006402 mRNA catabolic process PR:000037416 PMID:22407295 EXP NCBITaxon:3702 UniProtKB:Q9SJF3-1 20140403 PRO:LVM PR:000037416 mRNA-decapping enzyme-like protein unphosphorylated 1 (Arabidopsis thaliana) At-DCP1A/UnPhos:1|UniProtKB:Q9SJF3, Ser-237, PR:000026291 enables GO:0005515 protein binding PR:Q9C658 PMID:22407295 IPI NCBITaxon:3702 UniProtKB:Q9SJF3-1 20140403 PRO:LVM PR:000037416 mRNA-decapping enzyme-like protein unphosphorylated 1 (Arabidopsis thaliana) At-DCP1A/UnPhos:1|UniProtKB:Q9SJF3, Ser-237, PR:000026291 acts_upstream_of_or_within GO:0006402 mRNA catabolic process PMID:22407295 EXP NCBITaxon:3702 UniProtKB:Q9SJF3-1 20140403 PRO:LVM PR:000037421 nitrate reductase [NADH] 2 phosphorylated 1 (Arabidopsis thaliana) At-NR2/Phos:1|UniProtKB:P11035, Ser-627, MOD:00046 increased enables GO:0008940 nitrate reductase activity PR:000037422 PMID:20870959 EXP NCBITaxon:3702 UniProtKB:P11035-1 20140415 PRO:LVM PR:000037424 protein ETHYLENE INSENSITIVE 3 phosphorylated 1 (Arabidopsis thaliana) At-EIN3/Phos:1|UniProtKB:O24606, Thr-592, MOD:00047 located_in GO:0005634 nucleus PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606-1 20140415 PRO:LVM PR:000037424 protein ETHYLENE INSENSITIVE 3 phosphorylated 1 (Arabidopsis thaliana) At-EIN3/Phos:1|UniProtKB:O24606, Thr-592, MOD:00047 acts_upstream_of_or_within GO:0010105 negative regulation of ethylene-activated signaling pathway PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606-1 20140415 PRO:LVM PR:000037425 protein ETHYLENE INSENSITIVE 3 phosphorylated 2 (Arabidopsis thaliana) At-EIN3/Phos:2|UniProtKB:O24606, Thr-174, MOD:00047 located_in GO:0005634 nucleus PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606-1 20140415 PRO:LVM PR:000037427 CBL-interacting serine/threonine-protein kinase 24 phosphorylated 1 (Arabidopsis thaliana) At-CIPK24/Phos:1|SOS2 authophosphorylated|UniProtKB:Q9LDI3, Ser-228, MOD:00046 enables GO:0004672 protein kinase activity PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3-1 20140415 PRO:LVM PR:000037427 CBL-interacting serine/threonine-protein kinase 24 phosphorylated 1 (Arabidopsis thaliana) At-CIPK24/Phos:1|SOS2 authophosphorylated|UniProtKB:Q9LDI3, Ser-228, MOD:00046 acts_upstream_of_or_within GO:0009651 response to salt stress PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3-1 20140415 PRO:LVM PR:000037428 CBL-interacting serine/threonine-protein kinase 24 phosphorylated 2 (Arabidopsis thaliana) At-CIPK24/Phos:2|UniProtKB:Q9LDI3, Thr-168, MOD:00047 acts_upstream_of_or_within GO:0009651 response to salt stress PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3-1 20140415 PRO:LVM PR:000037429 CBL-interacting serine/threonine-protein kinase 24 phosphorylated 3 (Arabidopsis thaliana) At-CIPK24/Phos:3|UniProtKB:Q9LDI3, Thr-168, MOD:00047|Ser-228, MOD:00046 acts_upstream_of_or_within GO:0009651 response to salt stress PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3-1 20140415 PRO:CNA PR:000037438 calcineurin B-like protein 2 phosphorylated 1 (Arabidopsis thaliana) At-CBL2/Phos:1|UniProtKB:Q8LAS7, Ser-216, MOD:00046 increased enables GO:0019901 protein kinase binding PR:000037439 PR:O22932 PMID:21685179 IPI NCBITaxon:3702 UniProtKB:Q8LAS7-1 20140421 PRO:LVM PR:000037438 calcineurin B-like protein 2 phosphorylated 1 (Arabidopsis thaliana) At-CBL2/Phos:1|UniProtKB:Q8LAS7, Ser-216, MOD:00046 increased enables GO:0019901 protein kinase binding PR:000037439 PR:Q9LDI3 PMID:21685179 IPI NCBITaxon:3702 UniProtKB:Q8LAS7-1 20140421 PRO:LVM PR:000037439 calcineurin B-like protein 2 unphosphorylated 1 (Arabidopsis thaliana) At-CBL2/UnPhos:1|UniProtKB:Q8LAS7, Ser-216, PR:000026291 enables GO:0019901 protein kinase binding PR:O22932 PMID:21685179 IPI NCBITaxon:3702 UniProtKB:Q8LAS7-1 20140415 PRO:CNA PR:000037439 calcineurin B-like protein 2 unphosphorylated 1 (Arabidopsis thaliana) At-CBL2/UnPhos:1|UniProtKB:Q8LAS7, Ser-216, PR:000026291 enables GO:0019901 protein kinase binding PR:Q9LDI3 PMID:21685179 IPI NCBITaxon:3702 UniProtKB:Q8LAS7-1 20140415 PRO:CNA PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) enables GO:0004713 protein tyrosine kinase activity Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA Target=PR:000037447 (TIRAP protein in this complex). PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) located_in GO:0005886 plasma membrane Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human) MAL:BTK:activated TLR4 (human)|MAL:PI(4,5)P2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_120882 EXP NCBITaxon:9606 Reactome:REACT_124673 20140514 PRO:CNA PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human) p-4Y-MAL:PI(4,5)P2:BTK:activated TLR4 (human)|p-4Y-TIRAP:PI(4,5)P2:BTK:activated TLR4 (human)|p4Y-MAL:PIP2:BTK:activated TLR4 (human) located_in GO:0005886 plasma membrane Reactome:REACT_125282 EXP NCBITaxon:9606 Reactome:REACT_125282 20140514 PRO:CNA PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human) p-4Y-MAL:PI(4,5)P2:BTK:activated TLR4 (human)|p-4Y-TIRAP:PI(4,5)P2:BTK:activated TLR4 (human)|p4Y-MAL:PIP2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_125282 EXP NCBITaxon:9606 Reactome:REACT_125282 20140514 PRO:CNA PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human) p-4Y-MAL:PI(4,5)P2:BTK:activated TLR4 (human)|p-4Y-TIRAP:PI(4,5)P2:BTK:activated TLR4 (human)|p4Y-MAL:PIP2:BTK:activated TLR4 (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_125282 EXP NCBITaxon:9606 Reactome:REACT_125282 20140514 PRO:CNA PR:000037461 viral dsRNA:TLR3 complex (chicken) located_in GO:0010008 endosome membrane Reactome:REACT_24923 EXP NCBITaxon:9031 Reactome:REACT_24931 20140513 PRO:VS PR:000037461 viral dsRNA:TLR3 complex (chicken) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_24923 EXP NCBITaxon:9031 Reactome:REACT_24931 20140513 PRO:VS PR:000037463 LPS:secreted CD14 alpha (human) h-LPS:sCD14alpha|sCD14/LPS complex (human) located_in GO:0005615 extracellular space Reactome:REACT_7856 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037463 LPS:secreted CD14 alpha (human) h-LPS:sCD14alpha|sCD14/LPS complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037464 LPS:GPI-anchored CD14 complex (human) h-LPS:mCD14|mCD14/LPS complex (human) located_in GO:0005886 plasma membrane Reactome:REACT_7856 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037464 LPS:GPI-anchored CD14 complex (human) h-LPS:mCD14|mCD14/LPS complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037466 LPS:transmembrane CD14 complex (chicken) located_in GO:0009986 cell surface PMID:18761368|PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA PR:000037466 LPS:transmembrane CD14 complex (chicken) acts_upstream_of_or_within GO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of CD14 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex LPS:CD14 has been inferred by curator based on expression data and conserved TLR signaling response. Note=In response to laryngotracheitis virus. PR:000037466 LPS:transmembrane CD14 complex (chicken) acts_upstream_of_or_within GO:0051607 defense response to virus PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of CD14 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex LPS:CD14 has been inferred by curator based on expression data and conserved TLR signaling response. Note=In response to laryngotracheitis virus. PR:000037469 CD14 molecule cleaved 1 soluble form (mouse) mCD14/iso:1/Clv:1/soluble|Secreted CD14 (mouse)|UniProtKB:P10810-1, 16-358 expressed_in CL:0000129 microglial cell PMID:24659539 EXP NCBITaxon:10090 UniProtKB:P10810-1 20140514 PRO:CNA Note=Expressed in supernatant of microglial cells PR:000037473 LY96:TLR4 complex (chicken) chick-(LY96:TLR4)|chTLR4/chMD-2 complex|MD2:TLR4 complex (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_26915 EXP NCBITaxon:9031 Reactome:REACT_26915 20140514 PRO:CNA PR:000037473 LY96:TLR4 complex (chicken) chick-(LY96:TLR4)|chTLR4/chMD-2 complex|MD2:TLR4 complex (chicken) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:18768894 EXP NCBITaxon:9031 Reactome:REACT_26915 20140514 PRO:CNA PR:000037473 LY96:TLR4 complex (chicken) chick-(LY96:TLR4)|chTLR4/chMD-2 complex|MD2:TLR4 complex (chicken) NOT acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18768894 EXP NCBITaxon:9031 Reactome:REACT_26915 20140514 PRO:CNA PR:000037474 activated TLR4 complex (chicken) chick-(LY96:LPS:TLR4)|chick-TLR4actv|LY96:LPS:TLR4 complex (chicken)|MD2:LPS:TLR4 (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_25442 EXP NCBITaxon:9031 Reactome:REACT_25442 20140514 PRO:CNA PR:000037474 activated TLR4 complex (chicken) chick-(LY96:LPS:TLR4)|chick-TLR4actv|LY96:LPS:TLR4 complex (chicken)|MD2:LPS:TLR4 (chicken) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:18768894 EXP NCBITaxon:9031 Reactome:REACT_25442 20140514 PRO:CNA PR:000037474 activated TLR4 complex (chicken) chick-(LY96:LPS:TLR4)|chick-TLR4actv|LY96:LPS:TLR4 complex (chicken)|MD2:LPS:TLR4 (chicken) acts_upstream_of_or_within GO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of TLR4 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex with MD2 has been inferred by curator based on PMID:18768894. Note=In response to laryngotracheitis virus. PR:000037474 activated TLR4 complex (chicken) chick-(LY96:LPS:TLR4)|chick-TLR4actv|LY96:LPS:TLR4 complex (chicken)|MD2:LPS:TLR4 (chicken) acts_upstream_of_or_within GO:0051607 defense response to virus PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of TLR4 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex with MD2 has been inferred by curator based on PMID:18768894. Note=In response to laryngotracheitis virus. PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) chick-(MYD88:TIRAP:TLR4actv)|MYD88:MAL:activated TLR4 receptor (chicken)|MYD88:MAL:LY96:TLR4:LPS complex (chicken) located_in GO:0005886 plasma membrane Reactome:REACT_26615 EXP NCBITaxon:9031 Reactome:REACT_26615 20140514 PRO:CNA PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) chick-(MYD88:TIRAP:TLR4actv)|MYD88:MAL:activated TLR4 receptor (chicken)|MYD88:MAL:LY96:TLR4:LPS complex (chicken) acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25089 EXP NCBITaxon:9031 Reactome:REACT_26615 20140514 PRO:CNA PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken) chick-(MYD88:TIRAP:TLR4actv)|MYD88:MAL:activated TLR4 receptor (chicken)|MYD88:MAL:LY96:TLR4:LPS complex (chicken) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_25089 EXP NCBITaxon:9031 Reactome:REACT_26615 20140514 PRO:CNA PR:000037476 lipopolysaccharide receptor complex 3 (mouse) m(LPSR:3)|TLR4:MD2:LPS:CD14 (mouse) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:12196527 EXP NCBITaxon:10090 20140514 PRO:CNA PR:000037504 DNA (cytosine-5)-methyltransferase 1 unphosphorylated 1 (human) hDNMT1/UnPhos:1|UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291 enables GO:0005515 protein binding PR:P12004 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037504 DNA (cytosine-5)-methyltransferase 1 unphosphorylated 1 (human) hDNMT1/UnPhos:1|UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291 enables GO:0005515 protein binding PR:Q96T88 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037505 DNA (cytosine-5)-methyltransferase 1 phosphorylated 1 (human) hDNMT1/Phos:1|pDnmt1S127|UniProtKB:P26358-1, Ser-127, MOD:00046 decreased enables GO:0005515 protein binding PR:000037504 PR:P12004 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037505 DNA (cytosine-5)-methyltransferase 1 phosphorylated 1 (human) hDNMT1/Phos:1|pDnmt1S127|UniProtKB:P26358-1, Ser-127, MOD:00046 decreased enables GO:0005515 protein binding PR:000037504 PR:Q96T88 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037506 DNA (cytosine-5)-methyltransferase 1 phosphorylated 2 (human) hDNMT1/Phos:2|pDnmt1S127/S143|UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046 decreased enables GO:0005515 protein binding PR:000037504 PR:P12004 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037506 DNA (cytosine-5)-methyltransferase 1 phosphorylated 2 (human) hDNMT1/Phos:2|pDnmt1S127/S143|UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046 decreased enables GO:0005515 protein binding PR:000037504 PR:Q96T88 PMID:20613874 IPI NCBITaxon:9606 UniProtKB:P26358-1 20140718 PRO:KER PR:000037507 transcriptional coactivator YAP1 isoform 3 unphosphorylated 1 (human) hYAP1/iso:3/UnPhos:1|UniProtKB:P46937-3, Tyr-357, PR:000026291 enables GO:0005515 protein binding PR:O15350 PMID:21214929|PMID:21562856 IPI NCBITaxon:9606 UniProtKB:P46937-3 20140718 PRO:KER Note=A?(25-35) induced YAP translocation from cytoplasm to nucleus accompanied with the increased phosphorylation on Y357, resulting in the enhancement of interaction between YAP and p73. PR:000037508 transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human) hYAP1/iso:3/Phos:1|UniProtKB:P46937-3, Tyr-357, MOD:00048 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:21562856 EXP NCBITaxon:9606 UniProtKB:P46937-3 20140718 PRO:KER PR:000037508 transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human) hYAP1/iso:3/Phos:1|UniProtKB:P46937-3, Tyr-357, MOD:00048 associated_with_disease_suppression DOID:162 cancer PMID:21214929 EXP NCBITaxon:9606 UniProtKB:P46937-3 20140718 PRO:KER PR:000037508 transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human) hYAP1/iso:3/Phos:1|UniProtKB:P46937-3, Tyr-357, MOD:00048 located_in GO:0005634 nucleus PMID:21562856 IDA NCBITaxon:9606 UniProtKB:P46937-3 20140718 PRO:CNA Note=A?(25-35) induced YAP translocation from cytoplasm to nucleus accompanied with the increased phosphorylation on Y357, resulting in the enhancement of interaction between YAP and p73. PR:000037508 transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human) hYAP1/iso:3/Phos:1|UniProtKB:P46937-3, Tyr-357, MOD:00048 increased enables GO:0005515 protein binding PR:000037507 PR:O15350 PMID:21214929|PMID:21562856 IPI NCBITaxon:9606 UniProtKB:P46937-3 20140718 PRO:KER Note=A?(25-35) induced YAP translocation from cytoplasm to nucleus accompanied with the increased phosphorylation on Y357, resulting in the enhancement of interaction between YAP and p73. PR:000037510 transcriptional coactivator YAP1 phosphorylated 1 (human) hYap1 Ser127|hYAP1/Phos:1|UniProtKB:P46937-1, Ser-127, MOD:00046 associated_with_disease_progression DOID:162 cancer PMID:21214929 EXP NCBITaxon:9606 UniProtKB:P46937-1 20140718 PRO:KER PR:000037510 transcriptional coactivator YAP1 phosphorylated 1 (human) hYap1 Ser127|hYAP1/Phos:1|UniProtKB:P46937-1, Ser-127, MOD:00046 associated_with_disease_suppression DOID:10652 Alzheimer's disease PMID:21945154 EXP NCBITaxon:9606 UniProtKB:P46937-1 20140718 PRO:KER PR:000037510 transcriptional coactivator YAP1 phosphorylated 1 (human) hYap1 Ser127|hYAP1/Phos:1|UniProtKB:P46937-1, Ser-127, MOD:00046 enables GO:0005515 protein binding PR:000003237 PMID:21214929 IPI NCBITaxon:9606 UniProtKB:P46937-1 20140718 PRO:KER PR:000037510 transcriptional coactivator YAP1 phosphorylated 1 (human) hYap1 Ser127|hYAP1/Phos:1|UniProtKB:P46937-1, Ser-127, MOD:00046 decreased enables GO:0005515 protein binding PR:000037509 PR:O15350 PMID:21945154 IPI NCBITaxon:9606 UniProtKB:P46937-1 20140718 PRO:KER PR:000037511 G1/S-specific cyclin-D1 unphosphorylated 1 (human) hCCND1/UnPhos:1|UniProtKB:P24385, Thr-286, PR:000026291 associated_with_disease_progression DOID:162 cancer PMID:17407548 EXP NCBITaxon:9606 UniProtKB:P24385-1 20140718 PRO:KER PR:000037515 catenin beta-1 isoform 1 phosphorylated 11 (human) hCTNNB1/iso:1/Phos:11|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046 decreased enables GO:0003713 transcription coactivator activity PR:000037772 PMID:20307497 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140718 PRO:KER PR:000037515 catenin beta-1 isoform 1 phosphorylated 11 (human) hCTNNB1/iso:1/Phos:11|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046 decreased acts_upstream_of_or_within GO:0008283 cell population proliferation PR:000037772 PMID:20307497 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140718 PRO:KER PR:000037515 catenin beta-1 isoform 1 phosphorylated 11 (human) hCTNNB1/iso:1/Phos:11|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046 decreased acts_upstream_of_or_within GO:0060070 canonical Wnt signaling pathway PR:000037772 PMID:20307497 EXP NCBITaxon:9606 UniProtKB:P35222-1 20140718 PRO:KER PR:000037515 catenin beta-1 isoform 1 phosphorylated 11 (human) hCTNNB1/iso:1/Phos:11|UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046 increased enables GO:0005515 protein binding PR:000037772 PR:Q9Y297 PMID:16996060|PMID:21152425|PMID:23071615 IPI NCBITaxon:9606 UniProtKB:P35222-1 20140718 PRO:KER PR:000037517 DNMT1:PCNA:UHRF1 complex (human) DNMT1-PCNA-UHRF1|DNMT1/PCNA/UHRF1 associated_with_disease_suppression DOID:162 cancer PMID:20613874 EXP NCBITaxon:9606 20140718 PRO:KER PR:000037518 amyloid-beta precursor protein sequence variant A673V (human) hAPP/var:A673V|UniProtKB:P05067-1, Ala-673, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-a673v EXP NCBITaxon:9606 Alzforum:app-a673v 20180510 PRO:DAN PR:000037519 amyloid-beta precursor protein sequence variant D678H (human) hAPP/var:D678H|Taiwanese APP|UniProtKB:P05067-1, Asp-678, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-d678h-taiwanese EXP NCBITaxon:9606 Alzforum:app-d678h-taiwanese 20180510 PRO:DAN PR:000037520 amyloid-beta precursor protein sequence variant K687N (human) hAPP/var:K687N|UniProtKB:P05067-1, Lys-687, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:app-k687n EXP NCBITaxon:9606 Alzforum:app-k687n 20180510 PRO:DAN PR:000037525 microtubule-associated protein tau sequence variant K257T (human) hMAPT/var:K257T|UniProtKB:P10636-8, Lys-257, CHEBI:30013 associated_with_disease_progression DOID:11870 Pick's disease PMID:11089577|PMID:11117542|UniProtKB_VAR:VAR_010344 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010344 20120412 PRO:DAN PR:000037525 microtubule-associated protein tau sequence variant K257T (human) hMAPT/var:K257T|UniProtKB:P10636-8, Lys-257, CHEBI:30013 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-k257t EXP NCBITaxon:9606 Alzforum:mapt-k257t 20180510 PRO:DAN PR:000037527 microtubule-associated protein tau sequence variant L266V (human) hMAPT/var:L266V|UniProtKB:P10636-8, Leu-266, CHEBI:30015 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:12509859|UniProtKB_VAR:VAR_019662 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019662 20120412 PRO:DAN PR:000037528 microtubule-associated protein tau sequence variant G272V (human) hMAPT/var:G272V|UniProtKB:P10636-8, Gly-272, CHEBI:30015 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:9641683|PMID:9973279|UniProtKB_VAR:VAR_010345 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010345 20120412 PRO:DAN PR:000037530 microtubule-associated protein tau sequence variant N279K (human) hMAPT/var:N279K|UniProtKB:P10636-8, Asn-279, CHEBI:29967 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10412802|PMID:10489057|PMID:10802785|PMID:12473774|PMID:9789048|UniProtKB_VAR:VAR_010346 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010346 20120412 PRO:DAN PR:000037531 microtubule-associated protein tau sequence variant K280del (human) hMAPT/var:K280del|UniProtKB:P10636-1, 1-596, 598-758|UniProtKB:P10636-8, 1-279, 281-441 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:9973279|UniProtKB_VAR:VAR_010347 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010347 20120412 PRO:DAN PR:000037532 microtubule-associated protein tau sequence variant L284R (human) hMAPT/var:L284R|UniProtKB:P10636-8, Leu-284, CHEBI:29952 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-l284r EXP NCBITaxon:9606 Alzforum:mapt-l284r 20180510 PRO:DAN PR:000037533 microtubule-associated protein tau sequence variant N296H (human) hMAPT/var:N296H|UniProtKB:P10636-8, Asn-296, CHEBI:29979 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:11585254|PMID:11906000|UniProtKB_VAR:VAR_019663 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019663 20120412 PRO:DAN PR:000037534 microtubule-associated protein tau sequence variant P301S (human) hMAPT/var:P301S|UniProtKB:P10636-8, Pro-301, CHEBI:29999 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10374757|PMID:10553987|PMID:11071507|PMID:16240366|UniProtKB_VAR:VAR_010349 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010349 20120412 PRO:DAN PR:000037536 microtubule-associated protein tau sequence variant P301L (human) hMAPT/var:P301L|UniProtKB:P10636-8, Pro-301, CHEBI:30006 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10214944|PMID:9641683|PMID:9736786|PMID:9789048|PMID:9973279|UniProtKB_VAR:VAR_010348 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010348 20120412 PRO:DAN PR:000037537 microtubule-associated protein tau sequence variant G303V (human) hMAPT/var:G303V|UniProtKB:P10636-8, Gly-303, CHEBI:30015 associated_with_disease_progression DOID:678 progressive supranuclear palsy PMID:16157753|UniProtKB_VAR:VAR_037439 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_037439 20120412 PRO:DAN PR:000037537 microtubule-associated protein tau sequence variant G303V (human) hMAPT/var:G303V|UniProtKB:P10636-8, Gly-303, CHEBI:30015 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-g303v EXP NCBITaxon:9606 Alzforum:mapt-g303v 20180510 PRO:DAN PR:000037539 microtubule-associated protein tau sequence variant S305N (human) hMAPT/var:S305N|UniProtKB:P10636-8, Ser-305, CHEBI:50347 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10208578|UniProtKB_VAR:VAR_010350 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010350 20120412 PRO:DAN PR:000037541 microtubule-associated protein tau sequence variant K317M (human) hMAPT/var:K317M|UniProtKB:P10636-8, Lys-317, CHEBI:16044 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-k317m EXP NCBITaxon:9606 Alzforum:mapt-k317m 20180510 PRO:DAN PR:000037541 microtubule-associated protein tau sequence variant K317M (human) hMAPT/var:K317M|UniProtKB:P10636-8, Lys-317, CHEBI:16044 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:15883319|UniProtKB_VAR:VAR_037440 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_037440 20120412 PRO:DAN PR:000037542 microtubule-associated protein tau sequence variant S320Y (human) hMAPT/var:S320Y|UniProtKB:P10636-8, Ser-320, CHEBI:46858 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-s320y EXP NCBITaxon:9606 Alzforum:mapt-s320y 20180510 PRO:DAN PR:000037543 microtubule-associated protein tau sequence variant S320F (human) hMAPT/var:S320F|UniProtKB:P10636-8, Ser-320, CHEBI:29997 associated_with_disease_progression DOID:11870 Pick's disease PMID:11891833|UniProtKB_VAR:VAR_019665 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019665 20120412 PRO:DAN PR:000037546 microtubule-associated protein tau sequence variant V337M (human) hMAPT/var:V337M|Seattle Family A MAPT|UniProtKB:P10636-8, Val-337, CHEBI:16044 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10214944|PMID:9629852|UniProtKB_VAR:VAR_010351 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010351 20120412 PRO:DAN PR:000037547 microtubule-associated protein tau sequence variant E342V (human) hMAPT/var:E342V|UniProtKB:P10636-8, Glu-342, CHEBI:30015 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:11117541|UniProtKB_VAR:VAR_019666 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019666 20120412 PRO:DAN PR:000037548 microtubule-associated protein tau sequence variant S352L (human) hMAPT/var:S352L|UniProtKB:P10636-8, Ser-352, CHEBI:30006 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-s352l EXP NCBITaxon:9606 Alzforum:mapt-s352l 20180510 PRO:DAN PR:000037550 microtubule-associated protein tau sequence variant K369I (human) hMAPT/var:K369I|UniProtKB:P10636-8, Lys-369, CHEBI:30009 associated_with_disease_progression DOID:11870 Pick's disease PMID:11601501|UniProtKB_VAR:VAR_019668 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_019668 20120412 PRO:DAN PR:000037551 microtubule-associated protein tau sequence variant G389R (human) hMAPT/var:G389R|UniProtKB:P10636-8, Gly-389, CHEBI:29952 associated_with_disease_progression DOID:11870 Pick's disease PMID:10604746|PMID:11117542|UniProtKB_VAR:VAR_010352 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010352 20120412 PRO:DAN PR:000037551 microtubule-associated protein tau sequence variant G389R (human) hMAPT/var:G389R|UniProtKB:P10636-8, Gly-389, CHEBI:29952 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-g389r-ga EXP NCBITaxon:9606 Alzforum:mapt-g389r-ga 20180510 PRO:DAN PR:000037552 microtubule-associated protein tau sequence variant R406W (human) hMAPT/var:R406W|UniProtKB:P10636-8, Arg-406, CHEBI:29954 associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10214944|PMID:11278002|PMID:11889249|PMID:14517953|PMID:9641683|PMID:9973279|UniProtKB_VAR:VAR_010353 EXP NCBITaxon:9606 UniProtKB_VAR:VAR_010353 20120412 PRO:DAN PR:000037553 microtubule-associated protein tau sequence variant N410H (human) hMAPT/var:N410H|UniProtKB:P10636-8, Asn-410, CHEBI:29979 associated_with_disease_progression DOID:680 tauopathy Alzforum:mapt-n410h EXP NCBITaxon:9606 Alzforum:mapt-n410h 20180510 PRO:DAN PR:000037557 presenilin-1 sequence variant A79V (human) hPSEN1/var:A79V|UniProtKB:P49768-1, Ala-79, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a79v EXP NCBITaxon:9606 Alzforum:psen1-a79v 20180510 PRO:DAN PR:000037558 presenilin-1 sequence variant V82L (human) hPSEN1/var:V82L|UniProtKB:P49768-1, Val-82, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v82l EXP NCBITaxon:9606 Alzforum:psen1-v82l 20180510 PRO:DAN PR:000037559 presenilin-1 sequence variant L85P (human) hPSEN1/var:L85P|UniProtKB:P49768-1, Leu-85, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l85p EXP NCBITaxon:9606 Alzforum:psen1-l85p 20180510 PRO:DAN PR:000037560 presenilin-1 sequence variant V89L (human) hPSEN1/var:V89L|UniProtKB:P49768-1, Val-89, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v89l EXP NCBITaxon:9606 Alzforum:psen1-v89l 20180510 PRO:DAN PR:000037561 presenilin-1 sequence variant C92S (human) hPSEN1/var:C92S|UniProtKB:P49768-1, Cys-92, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-c92s EXP NCBITaxon:9606 Alzforum:psen1-c92s 20180510 PRO:DAN PR:000037562 presenilin-1 sequence variant V94M (human) hPSEN1/var:V94M|UniProtKB:P49768-1, Val-94, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v94m EXP NCBITaxon:9606 Alzforum:psen1-v94m 20180510 PRO:DAN PR:000037563 presenilin-1 sequence variant V96F (human) hPSEN1/var:V96F|UniProtKB:P49768-1, Val-96, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v96f EXP NCBITaxon:9606 Alzforum:psen1-v96f 20180510 PRO:DAN PR:000037564 presenilin-1 sequence variant V97L (human) hPSEN1/var:V97L|UniProtKB:P49768-1, Val-97, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v97l EXP NCBITaxon:9606 Alzforum:psen1-v97l 20180510 PRO:DAN PR:000037565 presenilin-1 sequence variant F105I (human) hPSEN1/var:F105I|UniProtKB:P49768-1, Phe-105, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f105i EXP NCBITaxon:9606 Alzforum:psen1-f105i 20180510 PRO:DAN PR:000037566 presenilin-1 sequence variant F105V (human) hPSEN1/var:F105V|UniProtKB:P49768-1, Phe-105, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f105v EXP NCBITaxon:9606 Alzforum:psen1-f105v 20180510 PRO:DAN PR:000037567 presenilin-1 sequence variant F105C (human) hPSEN1/var:F105C|UniProtKB:P49768-1, Phe-105, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f105c EXP NCBITaxon:9606 Alzforum:psen1-f105c 20180510 PRO:DAN PR:000037568 presenilin-1 sequence variant F105L (human) hPSEN1/var:F105L|UniProtKB:P49768-1, Phe-105, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f105l EXP NCBITaxon:9606 Alzforum:psen1-f105l 20180510 PRO:DAN PR:000037569 presenilin-1 sequence variant L113Q (human) hPSEN1/var:L113Q|UniProtKB:P49768-1, Leu-113, CHEBI:30011 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l113q EXP NCBITaxon:9606 Alzforum:psen1-l113q 20180510 PRO:DAN PR:000037571 presenilin-1 sequence variant Y115H (human) hPSEN1/var:Y115H|UniProtKB:P49768-1, Tyr-115, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y115h EXP NCBITaxon:9606 Alzforum:psen1-y115h 20180510 PRO:DAN PR:000037572 presenilin-1 sequence variant Y115C (human) hPSEN1/var:Y115C|UniProtKB:P49768-1, Tyr-115, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y115c EXP NCBITaxon:9606 Alzforum:psen1-y115c 20180510 PRO:DAN PR:000037573 presenilin-1 sequence variant Y115D (human) hPSEN1/var:Y115D|UniProtKB:P49768-1, Tyr-115, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y115d EXP NCBITaxon:9606 Alzforum:psen1-y115d 20180510 PRO:DAN PR:000037574 presenilin-1 sequence variant T116I (human) hPSEN1/var:T116I|UniProtKB:P49768-1, Thr-116, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t116i EXP NCBITaxon:9606 Alzforum:psen1-t116i 20180510 PRO:DAN PR:000037575 presenilin-1 sequence variant T116N (human) hPSEN1/var:T116N|UniProtKB:P49768-1, Thr-116, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t116n EXP NCBITaxon:9606 Alzforum:psen1-t116n 20180510 PRO:DAN PR:000037576 presenilin-1 sequence variant P117S (human) hPSEN1/var:P117S|UniProtKB:P49768-1, Pro-117, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p117s EXP NCBITaxon:9606 Alzforum:psen1-p117s 20180510 PRO:DAN PR:000037577 presenilin-1 sequence variant P117R (human) hPSEN1/var:P117R|UniProtKB:P49768-1, Pro-117, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p117r EXP NCBITaxon:9606 Alzforum:psen1-p117r 20180510 PRO:DAN PR:000037578 presenilin-1 sequence variant P117A (human) hPSEN1/var:P117A|UniProtKB:P49768-1, Pro-117, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p117a EXP NCBITaxon:9606 Alzforum:psen1-p117a 20180510 PRO:DAN PR:000037579 presenilin-1 sequence variant P117L (human) hPSEN1/var:P117L|UniProtKB:P49768-1, Pro-117, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p117l EXP NCBITaxon:9606 Alzforum:psen1-p117l 20180510 PRO:DAN PR:000037580 presenilin-1 sequence variant E120K (human) hPSEN1/var:E120K|UniProtKB:P49768-1, Glu-120, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e120k EXP NCBITaxon:9606 Alzforum:psen1-e120k 20180510 PRO:DAN PR:000037581 presenilin-1 sequence variant E120G (human) hPSEN1/var:E120G|UniProtKB:P49768-1, Glu-120, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e120g EXP NCBITaxon:9606 Alzforum:psen1-e120g 20180510 PRO:DAN PR:000037582 presenilin-1 sequence variant E120D (human) hPSEN1/var:E120D|UniProtKB:P49768-1, Glu-120, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e120d EXP NCBITaxon:9606 Alzforum:psen1-e120d 20180510 PRO:DAN PR:000037582 presenilin-1 sequence variant E120D (human) hPSEN1/var:E120D|UniProtKB:P49768-1, Glu-120, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e120d-acDUPE EXP NCBITaxon:9606 Alzforum:psen1-e120d-acDUPE 20180510 PRO:DAN PR:000037583 presenilin-1 sequence variant E123K (human) hPSEN1/var:E123K|UniProtKB:P49768-1, Glu-123, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e123k EXP NCBITaxon:9606 Alzforum:psen1-e123k 20180510 PRO:DAN PR:000037584 presenilin-1 sequence variant N135D (human) hPSEN1/var:N135D|UniProtKB:P49768-1, Asn-135, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-n135d EXP NCBITaxon:9606 Alzforum:psen1-n135d 20180510 PRO:DAN PR:000037585 presenilin-1 sequence variant N135S (human) hPSEN1/var:N135S|UniProtKB:P49768-1, Asn-135, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-n135s EXP NCBITaxon:9606 Alzforum:psen1-n135s 20180510 PRO:DAN PR:000037586 presenilin-1 sequence variant A136G (human) hPSEN1/var:A136G|UniProtKB:P49768-1, Ala-136, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a136g EXP NCBITaxon:9606 Alzforum:psen1-a136g 20180510 PRO:DAN PR:000037587 presenilin-1 sequence variant M139T (human) hPSEN1/var:M139T|UniProtKB:P49768-1, Met-139, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m139t EXP NCBITaxon:9606 Alzforum:psen1-m139t 20180510 PRO:DAN PR:000037588 presenilin-1 sequence variant M139V (human) hPSEN1/var:M139V|UniProtKB:P49768-1, Met-139, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m139v EXP NCBITaxon:9606 Alzforum:psen1-m139v 20180510 PRO:DAN PR:000037589 presenilin-1 sequence variant M139K (human) hPSEN1/var:M139K|UniProtKB:P49768-1, Met-139, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m139k EXP NCBITaxon:9606 Alzforum:psen1-m139k 20180510 PRO:DAN PR:000037590 presenilin-1 sequence variant M139I (human) hPSEN1/var:M139I|UniProtKB:P49768-1, Met-139, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m139i-ga EXP NCBITaxon:9606 Alzforum:psen1-m139i-ga 20180510 PRO:DAN PR:000037590 presenilin-1 sequence variant M139I (human) hPSEN1/var:M139I|UniProtKB:P49768-1, Met-139, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m139i-gcDUPE EXP NCBITaxon:9606 Alzforum:psen1-m139i-gcDUPE 20180510 PRO:DAN PR:000037591 presenilin-1 sequence variant I143N (human) hPSEN1/var:I143N|UniProtKB:P49768-1, Ile-143, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i143n EXP NCBITaxon:9606 Alzforum:psen1-i143n 20180510 PRO:DAN PR:000037592 presenilin-1 sequence variant I143V (human) hPSEN1/var:I143V|UniProtKB:P49768-1, Ile-143, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i143v EXP NCBITaxon:9606 Alzforum:psen1-i143v 20180510 PRO:DAN PR:000037593 presenilin-1 sequence variant I143F (human) hPSEN1/var:I143F|UniProtKB:P49768-1, Ile-143, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i143f EXP NCBITaxon:9606 Alzforum:psen1-i143f 20180510 PRO:DAN PR:000037594 presenilin-1 sequence variant I143T (human) hPSEN1/var:I143T|UniProtKB:P49768-1, Ile-143, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i143t EXP NCBITaxon:9606 Alzforum:psen1-i143t 20180510 PRO:DAN PR:000037595 presenilin-1 sequence variant I143M (human) hPSEN1/var:I143M|UniProtKB:P49768-1, Ile-143, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i143m EXP NCBITaxon:9606 Alzforum:psen1-i143m 20180510 PRO:DAN PR:000037596 presenilin-1 sequence variant M146L (human) hPSEN1/var:M146L|UniProtKB:P49768-1, Met-146, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146l EXP NCBITaxon:9606 Alzforum:psen1-m146l 20180510 PRO:DAN PR:000037596 presenilin-1 sequence variant M146L (human) hPSEN1/var:M146L|UniProtKB:P49768-1, Met-146, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146l-acDUPE EXP NCBITaxon:9606 Alzforum:psen1-m146l-acDUPE 20180510 PRO:DAN PR:000037597 presenilin-1 sequence variant M146I (human) hPSEN1/var:M146I|UniProtKB:P49768-1, Met-146, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146i-ga EXP NCBITaxon:9606 Alzforum:psen1-m146i-ga 20180510 PRO:DAN PR:000037597 presenilin-1 sequence variant M146I (human) hPSEN1/var:M146I|UniProtKB:P49768-1, Met-146, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146i-gcDUPE EXP NCBITaxon:9606 Alzforum:psen1-m146i-gcDUPE 20180510 PRO:DAN PR:000037597 presenilin-1 sequence variant M146I (human) hPSEN1/var:M146I|UniProtKB:P49768-1, Met-146, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146i-gtDUPE EXP NCBITaxon:9606 Alzforum:psen1-m146i-gtDUPE 20180510 PRO:DAN PR:000037598 presenilin-1 sequence variant M146V (human) hPSEN1/var:M146V|UniProtKB:P49768-1, Met-146, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m146v EXP NCBITaxon:9606 Alzforum:psen1-m146v 20180510 PRO:DAN PR:000037599 presenilin-1 sequence variant T147P (human) hPSEN1/var:T147P|UniProtKB:P49768-1, Thr-147, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t147p EXP NCBITaxon:9606 Alzforum:psen1-t147p 20180510 PRO:DAN PR:000037600 presenilin-1 sequence variant T147I (human) hPSEN1/var:T147I|UniProtKB:P49768-1, Thr-147, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t147i EXP NCBITaxon:9606 Alzforum:psen1-t147i 20180510 PRO:DAN PR:000037601 presenilin-1 sequence variant L153V (human) hPSEN1/var:L153V|UniProtKB:P49768-1, Leu-153, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l153v EXP NCBITaxon:9606 Alzforum:psen1-l153v 20180510 PRO:DAN PR:000037602 presenilin-1 sequence variant Y154N (human) hPSEN1/var:Y154N|UniProtKB:P49768-1, Tyr-154, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y154n EXP NCBITaxon:9606 Alzforum:psen1-y154n 20180510 PRO:DAN PR:000037603 presenilin-1 sequence variant Y154C (human) hPSEN1/var:Y154C|UniProtKB:P49768-1, Tyr-154, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y154c EXP NCBITaxon:9606 Alzforum:psen1-y154c 20180510 PRO:DAN PR:000037604 presenilin-1 sequence variant H163Y (human) hPSEN1/var:H163Y|UniProtKB:P49768-1, His-163, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-h163y EXP NCBITaxon:9606 Alzforum:psen1-h163y 20180510 PRO:DAN PR:000037606 presenilin-1 sequence variant H163R (human) hPSEN1/var:H163R|UniProtKB:P49768-1, His-163, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-h163r EXP NCBITaxon:9606 Alzforum:psen1-h163r 20180510 PRO:DAN PR:000037607 presenilin-1 sequence variant W165G (human) hPSEN1/var:W165G|UniProtKB:P49768-1, Trp-165, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-w165g EXP NCBITaxon:9606 Alzforum:psen1-w165g 20180510 PRO:DAN PR:000037608 presenilin-1 sequence variant W165C (human) hPSEN1/var:W165C|UniProtKB:P49768-1, Trp-165, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-w165c EXP NCBITaxon:9606 Alzforum:psen1-w165c 20180510 PRO:DAN PR:000037609 presenilin-1 sequence variant L166R (human) hPSEN1/var:L166R|UniProtKB:P49768-1, Leu-166, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l166r EXP NCBITaxon:9606 Alzforum:psen1-l166r 20180510 PRO:DAN PR:000037610 presenilin-1 sequence variant L166P (human) hPSEN1/var:L166P|UniProtKB:P49768-1, Leu-166, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l166p EXP NCBITaxon:9606 Alzforum:psen1-l166p 20180510 PRO:DAN PR:000037611 presenilin-1 sequence variant L166H (human) hPSEN1/var:L166H|UniProtKB:P49768-1, Leu-166, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l166h EXP NCBITaxon:9606 Alzforum:psen1-l166h 20180510 PRO:DAN PR:000037612 presenilin-1 sequence variant L166del (human) hPSEN1/var:L166del|UniProtKB:P49768-1, 1-165, 167-467 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l166del EXP NCBITaxon:9606 Alzforum:psen1-l166del 20180510 PRO:DAN PR:000037613 presenilin-1 sequence variant I167del (human) hPSEN1/var:I167del|UniProtKB:P49768-1, 1-166, 168-467 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i167del EXP NCBITaxon:9606 Alzforum:psen1-i167del 20180510 PRO:DAN PR:000037614 presenilin-1 sequence variant I168del (human) hPSEN1/var:I168del|UniProtKB:P49768-1, 1-167, 169-467 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i168del EXP NCBITaxon:9606 Alzforum:psen1-i168del 20180510 PRO:DAN PR:000037615 presenilin-1 sequence variant S169L (human) hPSEN1/var:S169L|UniProtKB:P49768-1, Ser-169, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s169l EXP NCBITaxon:9606 Alzforum:psen1-s169l 20180510 PRO:DAN PR:000037616 presenilin-1 sequence variant S169P (human) hPSEN1/var:S169P|UniProtKB:P49768-1, Ser-169, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s169p EXP NCBITaxon:9606 Alzforum:psen1-s169p 20180510 PRO:DAN PR:000037617 presenilin-1 sequence variant S170F (human) hPSEN1/var:S170F|UniProtKB:P49768-1, Ser-170, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s170f EXP NCBITaxon:9606 Alzforum:psen1-s170f 20180510 PRO:DAN PR:000037618 presenilin-1 sequence variant L171P (human) hPSEN1/var:L171P|UniProtKB:P49768-1, Leu-171, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l171p EXP NCBITaxon:9606 Alzforum:psen1-l171p 20180510 PRO:DAN PR:000037619 presenilin-1 sequence variant L173W (human) hPSEN1/var:L173W|UniProtKB:P49768-1, Leu-173, CHEBI:29954 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l173w EXP NCBITaxon:9606 Alzforum:psen1-l173w 20180510 PRO:DAN PR:000037620 presenilin-1 sequence variant L173F (human) hPSEN1/var:L173F|UniProtKB:P49768-1, Leu-173, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l173f-gc EXP NCBITaxon:9606 Alzforum:psen1-l173f-gc 20180510 PRO:DAN PR:000037620 presenilin-1 sequence variant L173F (human) hPSEN1/var:L173F|UniProtKB:P49768-1, Leu-173, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l173f-gtDUPE EXP NCBITaxon:9606 Alzforum:psen1-l173f-gtDUPE 20180510 PRO:DAN PR:000037621 presenilin-1 sequence variant L174R (human) hPSEN1/var:L174R|UniProtKB:P49768-1, Leu-174, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l174r EXP NCBITaxon:9606 Alzforum:psen1-l174r 20180510 PRO:DAN PR:000037622 presenilin-1 sequence variant L174M (human) hPSEN1/var:L174M|UniProtKB:P49768-1, Leu-174, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l174m EXP NCBITaxon:9606 Alzforum:psen1-l174m 20180510 PRO:DAN PR:000037624 presenilin-1 sequence variant F177S (human) hPSEN1/var:F177S|UniProtKB:P49768-1, Phe-177, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f177s EXP NCBITaxon:9606 Alzforum:psen1-f177s 20180510 PRO:DAN PR:000037625 presenilin-1 sequence variant F177L (human) hPSEN1/var:F177L|UniProtKB:P49768-1, Phe-177, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f177l EXP NCBITaxon:9606 Alzforum:psen1-f177l 20180510 PRO:DAN PR:000037626 presenilin-1 sequence variant S178P (human) hPSEN1/var:S178P|UniProtKB:P49768-1, Ser-178, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s178p EXP NCBITaxon:9606 Alzforum:psen1-s178p 20180510 PRO:DAN PR:000037627 presenilin-1 sequence variant G183V (human) hPSEN1/var:G183V|UniProtKB:P49768-1, Gly-183, CHEBI:30015 associated_with_disease_progression DOID:680 tauopathy Alzforum:psen1-g183v EXP NCBITaxon:9606 Alzforum:psen1-g183v 20180510 PRO:DAN PR:000037628 presenilin-1 sequence variant E184D (human) hPSEN1/var:E184D|UniProtKB:P49768-1, Glu-184, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e184d EXP NCBITaxon:9606 Alzforum:psen1-e184d 20180510 PRO:DAN PR:000037630 presenilin-1 sequence variant G206A (human) hPSEN1/var:G206A|UniProtKB:P49768-1, Gly-206, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g206a EXP NCBITaxon:9606 Alzforum:psen1-g206a 20180510 PRO:DAN PR:000037631 presenilin-1 sequence variant G206S (human) hPSEN1/var:G206S|UniProtKB:P49768-1, Gly-206, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g206s EXP NCBITaxon:9606 Alzforum:psen1-g206s 20180510 PRO:DAN PR:000037632 presenilin-1 sequence variant G206V (human) hPSEN1/var:G206V|UniProtKB:P49768-1, Gly-206, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g206v EXP NCBITaxon:9606 Alzforum:psen1-g206v 20180510 PRO:DAN PR:000037633 presenilin-1 sequence variant G206D (human) hPSEN1/var:G206D|UniProtKB:P49768-1, Gly-206, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g206d EXP NCBITaxon:9606 Alzforum:psen1-g206d 20180510 PRO:DAN PR:000037634 presenilin-1 sequence variant G209E (human) hPSEN1/var:G209E|UniProtKB:P49768-1, Gly-209, CHEBI:29972 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g209e EXP NCBITaxon:9606 Alzforum:psen1-g209e 20180510 PRO:DAN PR:000037635 presenilin-1 sequence variant G209R (human) hPSEN1/var:G209R|UniProtKB:P49768-1, Gly-209, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g209r EXP NCBITaxon:9606 Alzforum:psen1-g209r 20180510 PRO:DAN PR:000037636 presenilin-1 sequence variant G209V (human) hPSEN1/var:G209V|UniProtKB:P49768-1, Gly-209, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g209v EXP NCBITaxon:9606 Alzforum:psen1-g209v 20180510 PRO:DAN PR:000037637 presenilin-1 sequence variant S212Y (human) hPSEN1/var:S212Y|UniProtKB:P49768-1, Ser-212, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s212y EXP NCBITaxon:9606 Alzforum:psen1-s212y 20180510 PRO:DAN PR:000037638 presenilin-1 sequence variant I213T (human) hPSEN1/var:I213T|UniProtKB:P49768-1, Ile-213, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i213t EXP NCBITaxon:9606 Alzforum:psen1-i213t 20180510 PRO:DAN PR:000037639 presenilin-1 sequence variant I213F (human) hPSEN1/var:I213F|UniProtKB:P49768-1, Ile-213, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i213f EXP NCBITaxon:9606 Alzforum:psen1-i213f 20180510 PRO:DAN PR:000037640 presenilin-1 sequence variant H214Y (human) hPSEN1/var:H214Y|UniProtKB:P49768-1, His-214, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-h214y EXP NCBITaxon:9606 Alzforum:psen1-h214y 20180510 PRO:DAN PR:000037641 presenilin-1 sequence variant H214D (human) hPSEN1/var:H214D|UniProtKB:P49768-1, His-214, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-h214d EXP NCBITaxon:9606 Alzforum:psen1-h214d 20180510 PRO:DAN PR:000037642 presenilin-1 sequence variant G217D (human) hPSEN1/var:G217D|UniProtKB:P49768-1, Gly-217, CHEBI:29958 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g217d EXP NCBITaxon:9606 Alzforum:psen1-g217d 20180510 PRO:DAN PR:000037643 presenilin-1 sequence variant G217R (human) hPSEN1/var:G217R|UniProtKB:P49768-1, Gly-217, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g217r EXP NCBITaxon:9606 Alzforum:psen1-g217r 20180510 PRO:DAN PR:000037644 presenilin-1 sequence variant L219F (human) hPSEN1/var:L219F|UniProtKB:P49768-1, Leu-219, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l219f EXP NCBITaxon:9606 Alzforum:psen1-l219f 20180510 PRO:DAN PR:000037645 presenilin-1 sequence variant L219P (human) hPSEN1/var:L219P|UniProtKB:P49768-1, Leu-219, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l219p EXP NCBITaxon:9606 Alzforum:psen1-l219p 20180510 PRO:DAN PR:000037646 presenilin-1 sequence variant Q222R (human) hPSEN1/var:Q222R|UniProtKB:P49768-1, Gln-222, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-q222r EXP NCBITaxon:9606 Alzforum:psen1-q222r 20180510 PRO:DAN PR:000037647 presenilin-1 sequence variant Q222H (human) hPSEN1/var:Q222H|UniProtKB:P49768-1, Gln-222, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-q222h EXP NCBITaxon:9606 Alzforum:psen1-q222h 20180510 PRO:DAN PR:000037648 presenilin-1 sequence variant Q223R (human) hPSEN1/var:Q223R|UniProtKB:P49768-1, Gln-223, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-q223r EXP NCBITaxon:9606 Alzforum:psen1-q223r 20180510 PRO:DAN PR:000037649 presenilin-1 sequence variant L226R (human) hPSEN1/var:L226R|UniProtKB:P49768-1, Leu-226, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l226r EXP NCBITaxon:9606 Alzforum:psen1-l226r 20180510 PRO:DAN PR:000037650 presenilin-1 sequence variant I229F (human) hPSEN1/var:I229F|UniProtKB:P49768-1, Ile-229, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i229f EXP NCBITaxon:9606 Alzforum:psen1-i229f 20180510 PRO:DAN PR:000037651 presenilin-1 sequence variant A231V (human) hPSEN1/var:A231V|UniProtKB:P49768-1, Ala-231, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a231v EXP NCBITaxon:9606 Alzforum:psen1-a231v 20180510 PRO:DAN PR:000037652 presenilin-1 sequence variant A231T (human) hPSEN1/var:A231T|UniProtKB:P49768-1, Ala-231, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a231t EXP NCBITaxon:9606 Alzforum:psen1-a231t 20180510 PRO:DAN PR:000037653 presenilin-1 sequence variant M233L (human) hPSEN1/var:M233L|UniProtKB:P49768-1, Met-233, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m233l-acDUPE EXP NCBITaxon:9606 Alzforum:psen1-m233l-acDUPE 20180510 PRO:DAN PR:000037654 presenilin-1 sequence variant M233T (human) hPSEN1/var:M233T|UniProtKB:P49768-1, Met-233, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m233t EXP NCBITaxon:9606 Alzforum:psen1-m233t 20180510 PRO:DAN PR:000037655 presenilin-1 sequence variant M233I (human) hPSEN1/var:M233I|UniProtKB:P49768-1, Met-233, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m233i-ga EXP NCBITaxon:9606 Alzforum:psen1-m233i-ga 20180510 PRO:DAN PR:000037655 presenilin-1 sequence variant M233I (human) hPSEN1/var:M233I|UniProtKB:P49768-1, Met-233, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m233i-gcDUPE EXP NCBITaxon:9606 Alzforum:psen1-m233i-gcDUPE 20180510 PRO:DAN PR:000037656 presenilin-1 sequence variant M233V (human) hPSEN1/var:M233V|UniProtKB:P49768-1, Met-233, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-m233v EXP NCBITaxon:9606 Alzforum:psen1-m233v 20180510 PRO:DAN PR:000037657 presenilin-1 sequence variant L235P (human) hPSEN1/var:L235P|UniProtKB:P49768-1, Leu-235, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l235p EXP NCBITaxon:9606 Alzforum:psen1-l235p 20180510 PRO:DAN PR:000037658 presenilin-1 sequence variant L235V (human) hPSEN1/var:L235V|UniProtKB:P49768-1, Leu-235, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l235v EXP NCBITaxon:9606 Alzforum:psen1-l235v 20180510 PRO:DAN PR:000037659 presenilin-1 sequence variant F237L (human) hPSEN1/var:F237L|UniProtKB:P49768-1, Phe-237, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f237l EXP NCBITaxon:9606 Alzforum:psen1-f237l 20180510 PRO:DAN PR:000037660 presenilin-1 sequence variant F237I (human) hPSEN1/var:F237I|UniProtKB:P49768-1, Phe-237, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f237i EXP NCBITaxon:9606 Alzforum:psen1-f237i 20180510 PRO:DAN PR:000037661 presenilin-1 sequence variant I238M (human) hPSEN1/var:I238M|UniProtKB:P49768-1, Ile-238, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i238m EXP NCBITaxon:9606 Alzforum:psen1-i238m 20180510 PRO:DAN PR:000037662 presenilin-1 sequence variant K239N (human) hPSEN1/var:K239N|UniProtKB:P49768-1, Lys-239, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-k239n EXP NCBITaxon:9606 Alzforum:psen1-k239n 20180510 PRO:DAN PR:000037663 presenilin-1 sequence variant T245P (human) hPSEN1/var:T245P|UniProtKB:P49768-1, Thr-245, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t245p EXP NCBITaxon:9606 Alzforum:psen1-t245p 20180510 PRO:DAN PR:000037664 presenilin-1 sequence variant A246E (human) hPSEN1/var:A246E|UniProtKB:P49768-1, Ala-246, CHEBI:29972 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a246e EXP NCBITaxon:9606 Alzforum:psen1-a246e 20180510 PRO:DAN PR:000037665 presenilin-1 sequence variant L248R (human) hPSEN1/var:L248R|UniProtKB:P49768-1, Leu-248, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l248r EXP NCBITaxon:9606 Alzforum:psen1-l248r 20180510 PRO:DAN PR:000037666 presenilin-1 sequence variant L248P (human) hPSEN1/var:L248P|UniProtKB:P49768-1, Leu-248, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l248p EXP NCBITaxon:9606 Alzforum:psen1-l248p 20180510 PRO:DAN PR:000037667 presenilin-1 sequence variant L250S (human) hPSEN1/var:L250S|UniProtKB:P49768-1, Leu-250, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l250s EXP NCBITaxon:9606 Alzforum:psen1-l250s 20180510 PRO:DAN PR:000037668 presenilin-1 sequence variant L250V (human) hPSEN1/var:L250V|UniProtKB:P49768-1, Leu-250, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l250v EXP NCBITaxon:9606 Alzforum:psen1-l250v 20180510 PRO:DAN PR:000037669 presenilin-1 sequence variant Y256S (human) hPSEN1/var:Y256S|UniProtKB:P49768-1, Tyr-256, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-y256s EXP NCBITaxon:9606 Alzforum:psen1-y256s 20180510 PRO:DAN PR:000037670 presenilin-1 sequence variant A260V (human) hPSEN1/var:A260V|UniProtKB:P49768-1, Ala-260, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a260v EXP NCBITaxon:9606 Alzforum:psen1-a260v 20180510 PRO:DAN PR:000037671 presenilin-1 sequence variant V261F (human) hPSEN1/var:V261F|UniProtKB:P49768-1, Val-261, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v261f EXP NCBITaxon:9606 Alzforum:psen1-v261f 20180510 PRO:DAN PR:000037672 presenilin-1 sequence variant V261L (human) hPSEN1/var:V261L|UniProtKB:P49768-1, Val-261, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v261l EXP NCBITaxon:9606 Alzforum:psen1-v261l 20180510 PRO:DAN PR:000037673 presenilin-1 sequence variant L262F (human) hPSEN1/var:L262F|UniProtKB:P49768-1, Leu-262, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l262f EXP NCBITaxon:9606 Alzforum:psen1-l262f 20180510 PRO:DAN PR:000037674 presenilin-1 sequence variant C263R (human) hPSEN1/var:C263R|UniProtKB:P49768-1, Cys-263, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-c263r EXP NCBITaxon:9606 Alzforum:psen1-c263r 20180510 PRO:DAN PR:000037675 presenilin-1 sequence variant C263F (human) hPSEN1/var:C263F|UniProtKB:P49768-1, Cys-263, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-c263f EXP NCBITaxon:9606 Alzforum:psen1-c263f 20180510 PRO:DAN PR:000037676 presenilin-1 sequence variant P264L (human) hPSEN1/var:P264L|UniProtKB:P49768-1, Pro-264, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p264l EXP NCBITaxon:9606 Alzforum:psen1-p264l 20180510 PRO:DAN PR:000037677 presenilin-1 sequence variant G266S (human) hPSEN1/var:G266S|UniProtKB:P49768-1, Gly-266, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g266s EXP NCBITaxon:9606 Alzforum:psen1-g266s 20180510 PRO:DAN PR:000037677 presenilin-1 sequence variant G266S (human) hPSEN1/var:G266S|UniProtKB:P49768-1, Gly-266, CHEBI:29999 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy Alzforum:psen1-g266s EXP NCBITaxon:9606 Alzforum:psen1-g266s 20180510 PRO:DAN PR:000037678 presenilin-1 sequence variant P267S (human) hPSEN1/var:P267S|UniProtKB:P49768-1, Pro-267, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p267s EXP NCBITaxon:9606 Alzforum:psen1-p267s 20180510 PRO:DAN PR:000037680 presenilin-1 sequence variant R269H (human) hPSEN1/var:R269H|UniProtKB:P49768-1, Arg-269, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r269h EXP NCBITaxon:9606 Alzforum:psen1-r269h 20180510 PRO:DAN PR:000037681 presenilin-1 sequence variant R269G (human) hPSEN1/var:R269G|UniProtKB:P49768-1, Arg-269, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r269g EXP NCBITaxon:9606 Alzforum:psen1-r269g 20180510 PRO:DAN PR:000037682 presenilin-1 sequence variant L271V (human) hPSEN1/var:L271V|UniProtKB:P49768-1, Leu-271, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l271v EXP NCBITaxon:9606 Alzforum:psen1-l271v 20180510 PRO:DAN PR:000037683 presenilin-1 sequence variant V272A (human) hPSEN1/var:V272A|UniProtKB:P49768-1, Val-272, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v272a EXP NCBITaxon:9606 Alzforum:psen1-v272a 20180510 PRO:DAN PR:000037684 presenilin-1 sequence variant E273A (human) hPSEN1/var:E273A|UniProtKB:P49768-1, Glu-273, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e273a EXP NCBITaxon:9606 Alzforum:psen1-e273a 20180510 PRO:DAN PR:000037685 presenilin-1 sequence variant T274R (human) hPSEN1/var:T274R|UniProtKB:P49768-1, Thr-274, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t274r EXP NCBITaxon:9606 Alzforum:psen1-t274r 20180510 PRO:DAN PR:000037686 presenilin-1 sequence variant A275V (human) hPSEN1/var:A275V|UniProtKB:P49768-1, Ala-275, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a275v EXP NCBITaxon:9606 Alzforum:psen1-a275v 20180510 PRO:DAN PR:000037687 presenilin-1 sequence variant R278I (human) hPSEN1/var:R278I|UniProtKB:P49768-1, Arg-278, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r278i EXP NCBITaxon:9606 Alzforum:psen1-r278i 20180510 PRO:DAN PR:000037688 presenilin-1 sequence variant R278K (human) hPSEN1/var:R278K|UniProtKB:P49768-1, Arg-278, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r278k EXP NCBITaxon:9606 Alzforum:psen1-r278k 20180510 PRO:DAN PR:000037689 presenilin-1 sequence variant R278T (human) hPSEN1/var:R278T|UniProtKB:P49768-1, Arg-278, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r278t EXP NCBITaxon:9606 Alzforum:psen1-r278t 20180510 PRO:DAN PR:000037690 presenilin-1 sequence variant R278S (human) hPSEN1/var:R278S|UniProtKB:P49768-1, Arg-278, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r278s EXP NCBITaxon:9606 Alzforum:psen1-r278s 20180510 PRO:DAN PR:000037691 presenilin-1 sequence variant E280A (human) hPSEN1/var:E280A|Paisa PSEN1|UniProtKB:P49768-1, Glu-280, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e280a-paisa EXP NCBITaxon:9606 Alzforum:psen1-e280a-paisa 20180510 PRO:DAN PR:000037692 presenilin-1 sequence variant E280G (human) hPSEN1/var:E280G|UniProtKB:P49768-1, Glu-280, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e280g EXP NCBITaxon:9606 Alzforum:psen1-e280g 20180510 PRO:DAN PR:000037693 presenilin-1 sequence variant L282V (human) hPSEN1/var:L282V|UniProtKB:P49768-1, Leu-282, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l282v EXP NCBITaxon:9606 Alzforum:psen1-l282v 20180510 PRO:DAN PR:000037694 presenilin-1 sequence variant L282F (human) hPSEN1/var:L282F|UniProtKB:P49768-1, Leu-282, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l282f EXP NCBITaxon:9606 Alzforum:psen1-l282f 20180510 PRO:DAN PR:000037695 presenilin-1 sequence variant L282R (human) hPSEN1/var:L282R|UniProtKB:P49768-1, Leu-282, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l282r EXP NCBITaxon:9606 Alzforum:psen1-l282r 20180510 PRO:DAN PR:000037696 presenilin-1 sequence variant P284L (human) hPSEN1/var:P284L|UniProtKB:P49768-1, Pro-284, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p284l EXP NCBITaxon:9606 Alzforum:psen1-p284l 20180510 PRO:DAN PR:000037697 presenilin-1 sequence variant P284S (human) hPSEN1/var:P284S|UniProtKB:P49768-1, Pro-284, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p284s EXP NCBITaxon:9606 Alzforum:psen1-p284s 20180510 PRO:DAN PR:000037698 presenilin-1 sequence variant A285V (human) hPSEN1/var:A285V|UniProtKB:P49768-1, Ala-285, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a285v EXP NCBITaxon:9606 Alzforum:psen1-a285v 20180510 PRO:DAN PR:000037699 presenilin-1 sequence variant L286V (human) hPSEN1/var:L286V|UniProtKB:P49768-1, Leu-286, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l286v EXP NCBITaxon:9606 Alzforum:psen1-l286v 20180510 PRO:DAN PR:000037700 presenilin-1 sequence variant L286P (human) hPSEN1/var:L286P|UniProtKB:P49768-1, Leu-286, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l286p EXP NCBITaxon:9606 Alzforum:psen1-l286p 20180510 PRO:DAN PR:000037700 presenilin-1 sequence variant L286P (human) hPSEN1/var:L286P|UniProtKB:P49768-1, Leu-286, CHEBI:50342 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy Alzforum:psen1-l286p EXP NCBITaxon:9606 Alzforum:psen1-l286p 20180510 PRO:DAN PR:000037701 presenilin-1 sequence variant T291P (human) hPSEN1/var:T291P|UniProtKB:P49768-1, Thr-291, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t291p EXP NCBITaxon:9606 Alzforum:psen1-t291p 20180510 PRO:DAN PR:000037705 presenilin-1 sequence variant R358Q (human) hPSEN1/var:R358Q|UniProtKB:P49768-1, Arg-358, CHEBI:30011 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r358q EXP NCBITaxon:9606 Alzforum:psen1-r358q 20180510 PRO:DAN PR:000037706 presenilin-1 sequence variant S365A (human) hPSEN1/var:S365A|UniProtKB:P49768-1, Ser-365, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s365a EXP NCBITaxon:9606 Alzforum:psen1-s365a 20180510 PRO:DAN PR:000037708 presenilin-1 sequence variant R377M (human) hPSEN1/var:R377M|UniProtKB:P49768-1, Arg-377, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r377m EXP NCBITaxon:9606 Alzforum:psen1-r377m 20180510 PRO:DAN PR:000037709 presenilin-1 sequence variant G378E (human) hPSEN1/var:G378E|UniProtKB:P49768-1, Gly-378, CHEBI:29972 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g378e EXP NCBITaxon:9606 Alzforum:psen1-g378e 20180510 PRO:DAN PR:000037709 presenilin-1 sequence variant G378E (human) hPSEN1/var:G378E|UniProtKB:P49768-1, Gly-378, CHEBI:29972 associated_with_disease_progression DOID:9246 cerebral amyloid angiopathy Alzforum:psen1-g378e EXP NCBITaxon:9606 Alzforum:psen1-g378e 20180510 PRO:DAN PR:000037710 presenilin-1 sequence variant G378V (human) hPSEN1/var:G378V|UniProtKB:P49768-1, Gly-378, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g378v EXP NCBITaxon:9606 Alzforum:psen1-g378v 20180510 PRO:DAN PR:000037711 presenilin-1 sequence variant L381V (human) hPSEN1/var:L381V|UniProtKB:P49768-1, Leu-381, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l381v EXP NCBITaxon:9606 Alzforum:psen1-l381v 20180510 PRO:DAN PR:000037712 presenilin-1 sequence variant L381F (human) hPSEN1/var:L381F|UniProtKB:P49768-1, Leu-381, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l381f EXP NCBITaxon:9606 Alzforum:psen1-l381f 20180510 PRO:DAN PR:000037713 presenilin-1 sequence variant G384A (human) hPSEN1/var:G384A|UniProtKB:P49768-1, Gly-384, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g384a EXP NCBITaxon:9606 Alzforum:psen1-g384a 20180510 PRO:DAN PR:000037714 presenilin-1 sequence variant F386S (human) hPSEN1/var:F386S|UniProtKB:P49768-1, Phe-386, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f386s EXP NCBITaxon:9606 Alzforum:psen1-f386s 20180510 PRO:DAN PR:000037715 presenilin-1 sequence variant S390I (human) hPSEN1/var:S390I|UniProtKB:P49768-1, Ser-390, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s390i EXP NCBITaxon:9606 Alzforum:psen1-s390i 20180510 PRO:DAN PR:000037716 presenilin-1 sequence variant V391F (human) hPSEN1/var:V391F|UniProtKB:P49768-1, Val-391, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-v391f EXP NCBITaxon:9606 Alzforum:psen1-v391f 20180510 PRO:DAN PR:000037717 presenilin-1 sequence variant L392V (human) hPSEN1/var:L392V|UniProtKB:P49768-1, Leu-392, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l392v EXP NCBITaxon:9606 Alzforum:psen1-l392v 20180510 PRO:DAN PR:000037718 presenilin-1 sequence variant L392P (human) hPSEN1/var:L392P|UniProtKB:P49768-1, Leu-392, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l392p EXP NCBITaxon:9606 Alzforum:psen1-l392p 20180510 PRO:DAN PR:000037719 presenilin-1 sequence variant G394V (human) hPSEN1/var:G394V|UniProtKB:P49768-1, Gly-394, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g394v EXP NCBITaxon:9606 Alzforum:psen1-g394v 20180510 PRO:DAN PR:000037720 presenilin-1 sequence variant N405S (human) hPSEN1/var:N405S|UniProtKB:P49768-1, Asn-405, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-n405s EXP NCBITaxon:9606 Alzforum:psen1-n405s 20180510 PRO:DAN PR:000037721 presenilin-1 sequence variant A409T (human) hPSEN1/var:A409T|UniProtKB:P49768-1, Ala-409, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a409t EXP NCBITaxon:9606 Alzforum:psen1-a409t 20180510 PRO:DAN PR:000037722 presenilin-1 sequence variant C410Y (human) hPSEN1/var:C410Y|UniProtKB:P49768-1, Cys-410, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-c410y EXP NCBITaxon:9606 Alzforum:psen1-c410y 20180510 PRO:DAN PR:000037724 presenilin-1 sequence variant L418F (human) hPSEN1/var:L418F|UniProtKB:P49768-1, Leu-418, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l418f EXP NCBITaxon:9606 Alzforum:psen1-l418f 20180510 PRO:DAN PR:000037725 presenilin-1 sequence variant L420R (human) hPSEN1/var:L420R|UniProtKB:P49768-1, Leu-420, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l420r EXP NCBITaxon:9606 Alzforum:psen1-l420r 20180510 PRO:DAN PR:000037726 presenilin-1 sequence variant L424H (human) hPSEN1/var:L424H|UniProtKB:P49768-1, Leu-424, CHEBI:29979 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l424h EXP NCBITaxon:9606 Alzforum:psen1-l424h 20180510 PRO:DAN PR:000037727 presenilin-1 sequence variant L424R (human) hPSEN1/var:L424R|UniProtKB:P49768-1, Leu-424, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l424r EXP NCBITaxon:9606 Alzforum:psen1-l424r 20180510 PRO:DAN PR:000037728 presenilin-1 sequence variant L424F (human) hPSEN1/var:L424F|UniProtKB:P49768-1, Leu-424, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l424f EXP NCBITaxon:9606 Alzforum:psen1-l424f 20180510 PRO:DAN PR:000037729 presenilin-1 sequence variant L424V (human) hPSEN1/var:L424V|UniProtKB:P49768-1, Leu-424, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l424v EXP NCBITaxon:9606 Alzforum:psen1-l424v 20180510 PRO:DAN PR:000037730 presenilin-1 sequence variant A426P (human) hPSEN1/var:A426P|UniProtKB:P49768-1, Ala-426, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a426p EXP NCBITaxon:9606 Alzforum:psen1-a426p 20180510 PRO:DAN PR:000037731 presenilin-1 sequence variant A431V (human) hPSEN1/var:A431V|UniProtKB:P49768-1, Ala-431, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a431v EXP NCBITaxon:9606 Alzforum:psen1-a431v 20180510 PRO:DAN PR:000037732 presenilin-1 sequence variant A431E (human) hPSEN1/var:A431E|Jalisco PSEN1|UniProtKB:P49768-1, Ala-431, CHEBI:29972 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a431e-jalisco EXP NCBITaxon:9606 Alzforum:psen1-a431e-jalisco 20180510 PRO:DAN PR:000037733 presenilin-1 sequence variant A434C (human) hPSEN1/var:A434C|UniProtKB:P49768-1, Ala-434, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a434c EXP NCBITaxon:9606 Alzforum:psen1-a434c 20180510 PRO:DAN PR:000037734 presenilin-1 sequence variant A434T (human) hPSEN1/var:A434T|UniProtKB:P49768-1, Ala-434, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a434t EXP NCBITaxon:9606 Alzforum:psen1-a434t 20180510 PRO:DAN PR:000037735 presenilin-1 sequence variant L435F (human) hPSEN1/var:L435F|UniProtKB:P49768-1, Leu-435, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l435f EXP NCBITaxon:9606 Alzforum:psen1-l435f 20180510 PRO:DAN PR:000037736 presenilin-1 sequence variant P436S (human) hPSEN1/var:P436S|UniProtKB:P49768-1, Pro-436, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p436s EXP NCBITaxon:9606 Alzforum:psen1-p436s 20180510 PRO:DAN PR:000037737 presenilin-1 sequence variant P436Q (human) hPSEN1/var:P436Q|UniProtKB:P49768-1, Pro-436, CHEBI:30011 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p436q EXP NCBITaxon:9606 Alzforum:psen1-p436q 20180510 PRO:DAN PR:000037738 presenilin-1 sequence variant I439S (human) hPSEN1/var:I439S|UniProtKB:P49768-1, Ile-439, CHEBI:29999 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i439s EXP NCBITaxon:9606 Alzforum:psen1-i439s 20180510 PRO:DAN PR:000037740 presenilin-1 sequence variant T440del (human) hPSEN1/var:T440del|UniProtKB:P49768-1, 1-439, 441-467 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t440del EXP NCBITaxon:9606 Alzforum:psen1-t440del 20180510 PRO:DAN PR:000037747 presenilin-2 sequence variant A85V (human) hPSEN2/var:A85V|UniProtKB:P49810-1, Ala-85, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-a85v EXP NCBITaxon:9606 Alzforum:psen2-a85v 20180510 PRO:DAN PR:000037748 presenilin-2 sequence variant T122P (human) hPSEN2/var:T122P|UniProtKB:P49810-1, Thr-122, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-t122p EXP NCBITaxon:9606 Alzforum:psen2-t122p 20180510 PRO:DAN PR:000037750 presenilin-2 sequence variant E126K (human) hPSEN2/var:E126K|UniProtKB:P49810-1, Glu-126, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-e126k EXP NCBITaxon:9606 Alzforum:psen2-e126k 20180510 PRO:DAN PR:000037753 presenilin-2 sequence variant N141I (human) hPSEN2/var:N141I|UniProtKB:P49810-1, Asn-141, CHEBI:30009|Volga German PSEN2 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-n141i-volga-german EXP NCBITaxon:9606 Alzforum:psen2-n141i-volga-german 20180510 PRO:DAN PR:000037754 presenilin-2 sequence variant N141Y (human) hPSEN2/var:N141Y|UniProtKB:P49810-1, Asn-141, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-n141y EXP NCBITaxon:9606 Alzforum:psen2-n141y 20180510 PRO:DAN PR:000037756 presenilin-2 sequence variant V148I (human) hPSEN2/var:V148I|UniProtKB:P49810-1, Val-148, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-v148i EXP NCBITaxon:9606 Alzforum:psen2-v148i 20180510 PRO:DAN PR:000037759 presenilin-2 sequence variant S175C (human) hPSEN2/var:S175C|UniProtKB:P49810-1, Ser-175, CHEBI:29950 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-s175c EXP NCBITaxon:9606 Alzforum:psen2-s175c 20180510 PRO:DAN PR:000037760 presenilin-2 sequence variant V214L (human) hPSEN2/var:V214L|UniProtKB:P49810-1, Val-214, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-v214l EXP NCBITaxon:9606 Alzforum:psen2-v214l 20180510 PRO:DAN PR:000037761 presenilin-2 sequence variant Q228L (human) hPSEN2/var:Q228L|UniProtKB:P49810-1, Gln-228, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-q228l EXP NCBITaxon:9606 Alzforum:psen2-q228l 20180510 PRO:DAN PR:000037763 presenilin-2 sequence variant M239V (human) hPSEN2/var:M239V|UniProtKB:P49810-1, Met-239, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-m239v EXP NCBITaxon:9606 Alzforum:psen2-m239v 20180510 PRO:DAN PR:000037764 presenilin-2 sequence variant M239I (human) hPSEN2/var:M239I|UniProtKB:P49810-1, Met-239, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-m239i EXP NCBITaxon:9606 Alzforum:psen2-m239i 20180510 PRO:DAN PR:000037768 presenilin-2 sequence variant T430M (human) hPSEN2/var:T430M|UniProtKB:P49810-1, Thr-430, CHEBI:16044 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-t430m EXP NCBITaxon:9606 Alzforum:psen2-t430m 20180510 PRO:DAN PR:000037777 roundabout homolog 3 isoform ROBO3.1 (mouse) mROBO3/iso:ROBO3[A/B]1|Robo3.1 located_in GO:0030424 axon MGI_ref:3834283|PMID:18466743 IDA NCBITaxon:10090 MGI:1343102 20140724 MGI:MGI occurs_in(EMAP:4251) PR:000037777 roundabout homolog 3 isoform ROBO3.1 (mouse) mROBO3/iso:ROBO3[A/B]1|Robo3.1 acts_upstream_of_or_within GO:0061642 chemoattraction of axon MGI_ref:3834283|PMID:18466743 IMP NCBITaxon:10090 MGI:1343102 20141016 MGI:MGI occurs_in(EMAP:3980),occurs_in(CL:0000678) PR:000037778 roundabout homolog 3 isoform ROBO3.2 (mouse) mROBO3/iso:ROBO3[A/B]2|Robo3.2 located_in GO:0030424 axon MGI_ref:3834283|PMID:18466743 IDA NCBITaxon:10090 MGI:1343102 20140724 MGI:MGI occurs_in(EMAP:4251) PR:000037778 roundabout homolog 3 isoform ROBO3.2 (mouse) mROBO3/iso:ROBO3[A/B]2|Robo3.2 acts_upstream_of_or_within GO:0061643 chemorepulsion of axon MGI_ref:3834283|PMID:18466743 IMP NCBITaxon:10090 MGI:1343102 20141016 MGI:MGI occurs_in(EMAP:3980),occurs_in(CL:0000678) PR:000037780 large ribosomal subunit protein uL13, initiator methionine removed acetylated and unphosphorylated 1 RPL13A/InitMet-/AcUnPhos:1 NOT part_of GO:0097452 GAIT complex MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:1351455 20140805 MGI:MGI PR:000037782 large ribosomal subunit protein uL13, initiator methionine removed acetylated and phosphorylated 1 (mouse) mRPL13A/InitMet-/AcPhos:1|PRO_0000133770, Ala-2, MOD:00050|Ser-77, MOD:00046|UniProtKB:P19253, 2-203, Ala-2, MOD:00050|Ser-77, MOD:00046 part_of GO:0097452 GAIT complex MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:1351455 20150115 MGI:MGI PR:000037785 bifunctional glutamate/proline--tRNA ligase phosphorylated 1 (mouse) mEPRS phosphorylated|mEPRS/Phos:1|UniProtKB:Q8CGC7, Ser-999, MOD:00046 part_of GO:0097452 GAIT complex MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:98214 MGI:97838 20140813 MGI:MGI PR:000037785 bifunctional glutamate/proline--tRNA ligase phosphorylated 1 (mouse) mEPRS phosphorylated|mEPRS/Phos:1|UniProtKB:Q8CGC7, Ser-999, MOD:00046 acts_upstream_of_or_within GO:0071346 cellular response to type II interferon MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:97857 MGI:97838 20140813 MGI:MGI PR:000037786 bifunctional glutamate/proline--tRNA ligase unphosphorylated 1 (mouse) mEPRS unphosphorylated|mEPRS/UnPhos:1|UniProtKB:Q8CGC7, Ser-999, PR:000026291 part_of GO:0017101 aminoacyl-tRNA synthetase multienzyme complex MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:97857 MGI:97838 20140813 MGI:MGI PR:000037786 bifunctional glutamate/proline--tRNA ligase unphosphorylated 1 (mouse) mEPRS unphosphorylated|mEPRS/UnPhos:1|UniProtKB:Q8CGC7, Ser-999, PR:000026291 NOT part_of GO:0097452 GAIT complex MGI_ref:5466658|PMID:23071094 IDA NCBITaxon:10090 MGI:98214 MGI:97838 20150115 MGI:MGI PR:000037791 interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human) hIRF7/iso:1/UnPhos:1|IRF-7 unphosphorylated (human)|UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291 located_in GO:0005737 cytoplasm Reactome:REACT_21735 EXP NCBITaxon:9606 20140718 PRO:CNA PR:000037794 MD2:GB4:TLR4 complex (mouse) acts_upstream_of_or_within GO:0034144 negative regulation of toll-like receptor 4 signaling pathway PMID:23471986 EXP NCBITaxon:10090 20140718 PRO:CNA PR:000037794 MD2:GB4:TLR4 complex (mouse) NOT enables GO:0001530 lipopolysaccharide binding PMID:23471986 EXP NCBITaxon:10090 20140718 PRO:CNA PR:000044350 zinc finger CCCH-type antiviral protein 1 isoform 3 prenylated-cysteine methyl ester 1 (mouse) mZC3HAV1/iso:3/IpCysEst:1|UniProtKB:D3Z5I1, 1-993, Cys-993, MOD:00116 located_in GO:0005764 lysosome MGI_ref:5499037|PMID:23776219 IMP NCBITaxon:10090 MGI:1926031 20140905 MGI:MGI part_of(CL:0000057) PR:000044350 zinc finger CCCH-type antiviral protein 1 isoform 3 prenylated-cysteine methyl ester 1 (mouse) mZC3HAV1/iso:3/IpCysEst:1|UniProtKB:D3Z5I1, 1-993, Cys-993, MOD:00116 located_in GO:0005770 late endosome MGI_ref:5499037|PMID:23776219 IMP NCBITaxon:10090 MGI:1926031 20140905 MGI:MGI part_of(CL:0000057) PR:000044370 STE20/SPS1-related proline-alanine-rich protein kinase isoform 3 (mouse) mSTK39/iso:3|SPAK2|UniProtKB:Q9Z1W9, 115-556 enables GO:0005515 protein binding PR:P55014-4 MGI_ref:5538439|PMID:24133122 IPI NCBITaxon:10090 MGI:1858416 20141009 MGI:MGI PR:000044372 dynamin-1 isoform ac (mouse) Dyn1ac (mouse)|mDNM1/iso:ac located_in GO:0001917 photoreceptor inner segment MGI_ref:3717940|PMID:17525220 IDA NCBITaxon:10090 MGI:107384 20141009 MGI:MGI occurs_in(MA:0000276) PR:000044373 tumor protein 63 DeltaN isoform (mouse) DeltaNp63|mTP63/iso:DeltaN acts_upstream_of_or_within GO:0002053 positive regulation of mesenchymal cell proliferation MGI_ref:3703103|PMID:17079275 IMP NCBITaxon:10090 MGI_allele:1934580 MGI:1330810 20070711 MGI:MGI acts_on_population_of(EMAP:12248) PR:000044373 tumor protein 63 DeltaN isoform (mouse) DeltaNp63|mTP63/iso:DeltaN acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:3703103|PMID:17079275 IMP NCBITaxon:10090 MGI_allele:1934580 MGI:1330810 20080214 MGI:MGI regulates_o_occurs_in(EMAP:12248),regulates_o_occurs_in(CL:0000066) PR:000044373 tumor protein 63 DeltaN isoform (mouse) DeltaNp63|mTP63/iso:DeltaN acts_upstream_of_or_within GO:0048745 smooth muscle tissue development MGI_ref:3703103|PMID:17079275 IMP NCBITaxon:10090 MGI_allele:1934580 MGI:1330810 20080214 MGI:MGI results_in_development_of(EMAP:12248) PR:000044373 tumor protein 63 DeltaN isoform (mouse) DeltaNp63|mTP63/iso:DeltaN acts_upstream_of_or_within GO:0060157 urinary bladder development MGI_ref:3703103|PMID:17079275 IMP NCBITaxon:10090 MGI_allele:1934580 MGI:1330810 20080214 MGI:MGI results_in_development_of(EMAP:12248) PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an enables GO:0046983 protein dimerization activity MGI_ref:4821669|PMID:20700442 IDA NCBITaxon:10090 MGI:107384 20141023 MGI:MGI occurs_in(MA:0000168) PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an acts_upstream_of_or_within GO:0006897 endocytosis MGI_ref:4821669|PMID:20700442 IDA NCBITaxon:10090 MGI:107384 20141023 MGI:MGI PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an acts_upstream_of_or_within GO:0007605 sensory perception of sound MGI_ref:4821669|PMID:20700442 IMP NCBITaxon:10090 MGI_allele:3033341 MGI:107384 20141023 MGI:MGI PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an acts_upstream_of_or_within GO:0008344 adult locomotory behavior MGI_ref:4821669|PMID:20700442 IMP NCBITaxon:10090 MGI_allele:3033341 MGI:107384 20141023 MGI:MGI PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an acts_upstream_of_or_within GO:0051262 protein tetramerization MGI_ref:4821669|PMID:20700442 IMP NCBITaxon:10090 MGI_allele:3033341 MGI:107384 20141023 MGI:MGI PR:000044457 dynamin-1 isoform an (mouse) Dyn1a (mouse)|mDNM1/iso:an acts_upstream_of_or_within GO:0051932 synaptic transmission, GABAergic MGI_ref:4821669|PMID:20700442 IMP NCBITaxon:10090 MGI_allele:3033341 MGI:107384 20141023 MGI:MGI occurs_in(MA:0000168),occurs_in(CL:0000598) PR:000044458 dynamin-1 isoform bn (mouse) Dyn1b (mouse)|mDNM1/iso:bn acts_upstream_of_or_within GO:0006897 endocytosis MGI_ref:4821669|PMID:20700442 IDA NCBITaxon:10090 MGI:107384 20141023 MGI:MGI PR:000044463 CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse) Bgp D glycosylated (mouse)|Bgp1a/4L glycosylated (mouse)|Ceacam1a isoform Long glycosylated (mouse)|Ceacam1a/D1-4L glycosylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+|PRO_0000014563, MOD:00160|UniProtKB:P31809-1, 35-521, MOD:00160 located_in GO:0009897 external side of plasma membrane MGI_ref:3693042|PMID:17081782 IDA NCBITaxon:10090 MGI:1347245 20150102 MGI:MGI occurs_in(CL:0000084),occurs_in(MA:0000142) PR:000044463 CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse) Bgp D glycosylated (mouse)|Bgp1a/4L glycosylated (mouse)|Ceacam1a isoform Long glycosylated (mouse)|Ceacam1a/D1-4L glycosylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+|PRO_0000014563, MOD:00160|UniProtKB:P31809-1, 35-521, MOD:00160 acts_upstream_of_or_within GO:0032703 negative regulation of interleukin-2 production MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI_allele:2448686|MGI_allele:3693674 MGI:1347245 20150115 MGI:MGI occurs_in(CL:0000084) PR:000044463 CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse) Bgp D glycosylated (mouse)|Bgp1a/4L glycosylated (mouse)|Ceacam1a isoform Long glycosylated (mouse)|Ceacam1a/D1-4L glycosylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+|PRO_0000014563, MOD:00160|UniProtKB:P31809-1, 35-521, MOD:00160 acts_upstream_of_or_within GO:0042130 negative regulation of T cell proliferation MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI_allele:3695215 MGI:1347245 20150102 MGI:MGI PR:000044463 CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse) Bgp D glycosylated (mouse)|Bgp1a/4L glycosylated (mouse)|Ceacam1a isoform Long glycosylated (mouse)|Ceacam1a/D1-4L glycosylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+|PRO_0000014563, MOD:00160|UniProtKB:P31809-1, 35-521, MOD:00160 acts_upstream_of_or_within GO:0042130 negative regulation of T cell proliferation MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3695215 MGI:1347245 20150109 MGI:MGI occurs_in(CL:0000084),occurs_in(MA:0000141) PR:000044464 CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse) Bgp D glycosylated and phosphorylated (mouse)|Bgp1a/4L glycosylated and phosphorylated (mouse)|Ceacam1a isoform Long glycosylated and phosphorylated (mouse)|Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1|PRO_0000014563, Tyr-488/Tyr-515, MOD:00048|MOD:00160|UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160 enables GO:0005515 protein binding PR:P29351 MGI_ref:1326994|PMID:9867848 IPI NCBITaxon:10090 MGI:1347245 20150101 MGI:MGI PR:000044464 CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse) Bgp D glycosylated and phosphorylated (mouse)|Bgp1a/4L glycosylated and phosphorylated (mouse)|Ceacam1a isoform Long glycosylated and phosphorylated (mouse)|Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1|PRO_0000014563, Tyr-488/Tyr-515, MOD:00048|MOD:00160|UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160 enables GO:0005515 protein binding PR:P29351 MGI_ref:86453|PMID:9047385 IPI NCBITaxon:10090 MGI:1347245 20150126 MGI:MGI PR:000044464 CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse) Bgp D glycosylated and phosphorylated (mouse)|Bgp1a/4L glycosylated and phosphorylated (mouse)|Ceacam1a isoform Long glycosylated and phosphorylated (mouse)|Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)|mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1|PRO_0000014563, Tyr-488/Tyr-515, MOD:00048|MOD:00160|UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160 enables GO:0005515 protein binding PR:P35235 MGI_ref:1326994|PMID:9867848 IPI NCBITaxon:10090 MGI:1347245 20150101 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 enables GO:0001618 virus receptor activity MGI_ref:49235|PMID:1719235 IDA NCBITaxon:10090 MGI:1347245 20141226 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 enables GO:0046790 virion binding MGI_ref:3053174|PMID:8380065 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 located_in GO:0009897 external side of plasma membrane MGI_ref:5608586|PMID:1633107 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 located_in GO:0009897 external side of plasma membrane MGI_ref:81180|PMID:8896983 IDA NCBITaxon:10090 MGI:1347245 20141231 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules MGI_ref:5608586|PMID:1633107 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0042102 positive regulation of T cell proliferation MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000084),occurs_in(MA:0000141) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0046718 symbiont entry into host cell MGI_ref:49235|PMID:1719235 IDA NCBITaxon:10090 MGI:1347245 20141226 MGI:MGI PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0048541 Peyer's patch development MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(MA:0000137) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0002639 positive regulation of immunoglobulin production MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(MA:0000137) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0070237 positive regulation of activation-induced cell death of T cells MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000084),occurs_in(MA:0000141) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:0070886 positive regulation of calcineurin-NFAT signaling cascade MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000905),occurs_in(MA:0002829) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000898),results_in_development_of(CL:0000905),occurs_in(MA:0000141)|occurs_in(CL:0000898),results_in_development_of(CL:0000905),occurs_in(MA:0002829)|occurs_in(CL:0000898),results_in_development_of(CL:0000905),occurs_in(MA:0000137)|occurs_in(CL:0000898),results_in_development_of(CL:0000905),occurs_in(MA:0003196) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000905),occurs_in(MA:0000141) PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse) Bgp A glycosylated (mouse)|Bgp1/4S glycosylated (mouse)|Ceacam1/D1-4S glycosylated (mouse)|Ceacam1a isoform Short glycosylated (mouse)|mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+|mmCGM1a glycosylated (mouse)|UniProtKB:P31809-2, 35-458, MOD:00160 acts_upstream_of_or_within GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation MGI_ref:5451119|PMID:23123061 IMP NCBITaxon:10090 MGI_allele:3053071|MGI_allele:5609428 MGI:1347245 20150123 MGI:MGI occurs_in(CL:0000898),regulates_o_results_in_development_of(CL:0000913),occurs_in(MA:0000141)|occurs_in(CL:0000898),regulates_o_results_in_development_of(CL:0000913),occurs_in(MA:0002829)|occurs_in(CL:0000898),regulates_o_results_in_development_of(CL:0000913),occurs_in(MA:0000137)|occurs_in(CL:0000898),regulates_o_results_in_development_of(CL:0000913),occurs_in(MA:0003196) PR:000044466 carcinoembryonic antigen-related cell adhesion molecule 1 sequence variant CEACAM1a (mouse) mCEACAM1a acts_upstream_of_or_within GO:0044794 positive regulation by host of viral process MGI_ref:1098064|PMID:9343248 IMP NCBITaxon:10090 MGI_allele:3027072 MGI:1347245 20150128 MGI:MGI PR:000044467 carcinoembryonic antigen-related cell adhesion molecule 1 sequence variant CEACAM1b (mouse) mCEACAM1b acts_upstream_of_or_within GO:0044793 negative regulation by host of viral process MGI_ref:1098064|PMID:9343248 IMP NCBITaxon:10090 MGI_allele:3053078 MGI:1347245 20150128 MGI:MGI PR:000044467 carcinoembryonic antigen-related cell adhesion molecule 1 sequence variant CEACAM1b (mouse) mCEACAM1b acts_upstream_of_or_within GO:0044828 negative regulation by host of viral genome replication MGI_ref:55926|PMID:6327825 IMP NCBITaxon:10090 MGI_allele:3053078 MGI:1347245 20141230 MGI:MGI occurs_in(CL:0000235) PR:000044469 CEACAM1a-4C1, signal peptide removed N-glycosylasparagine form (mouse) mCEACAM1a/iso:4C1/SigPep-/NGlycoAsn+|UniProtKB:Q3LFS5, 35-450, MOD:00160 located_in GO:0005615 extracellular space MGI_ref:3848729|PMID:19358828 IDA NCBITaxon:10090 MGI:1347245 20150105 MGI:MGI PR:000044469 CEACAM1a-4C1, signal peptide removed N-glycosylasparagine form (mouse) mCEACAM1a/iso:4C1/SigPep-/NGlycoAsn+|UniProtKB:Q3LFS5, 35-450, MOD:00160 acts_upstream_of_or_within GO:0044793 negative regulation by host of viral process MGI_ref:3848729|PMID:19358828 IDA NCBITaxon:10090 MGI:1347245 20150105 MGI:MGI PR:000044470 CEACAM1a-2C1, signal peptide removed N-glycosylasparagine form (mouse) mCEACAM1a/iso:2C1/SigPep-/NGlycoAsn+|UniProtKB:Q3LFS6, 35-270, MOD:00160 located_in GO:0005615 extracellular space MGI_ref:3848729|PMID:19358828 IDA NCBITaxon:10090 MGI:1347245 20150105 MGI:MGI PR:000044471 CEACAM1a-2, signal peptide removed N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/SigPep-/NGlycoAsn+|UniProtKB:Q3LFS7, 35-236, MOD:00160 located_in GO:0005615 extracellular space MGI_ref:3848729|PMID:19358828 IDA NCBITaxon:10090 MGI:1347245 20150105 MGI:MGI PR:000044472 CEACAM1b-2S, signal peptide removed N-glycosylasparagine form (mouse) Bgp C glycosylated (mouse)|BgpC glycosylated (mouse)|Ceacam1/D1,4S glycosylated (mouse)|mCEACAM1b/iso:2S/SigPep-/NGlycoAsn+|mmCGM2 glycosylated (mouse)|UniProtKB:Q99232, 35-278, MOD:00160 NOT enables GO:0046790 virion binding MGI_ref:3053174|PMID:8380065 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI PR:000044474 catenin beta-1 isoform 1 phosphorylated 12 (human) hCTNNB1/iso:1/Phos:12|UniProtKB:P35222-1, Thr-393, MOD:00047 acts_upstream_of_or_within GO:0016055 Wnt signaling pathway PMID:12700239 EXP NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER PR:000044474 catenin beta-1 isoform 1 phosphorylated 12 (human) hCTNNB1/iso:1/Phos:12|UniProtKB:P35222-1, Thr-393, MOD:00047 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:12700239 EXP NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER PR:000044474 catenin beta-1 isoform 1 phosphorylated 12 (human) hCTNNB1/iso:1/Phos:12|UniProtKB:P35222-1, Thr-393, MOD:00047 decreased enables GO:0005515 protein binding PR:000044476 PR:Q9YGY0 PMID:19565571 IPI NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER Note=Binding between proteins from heterogeneous species PR:000044476 catenin beta-1 isoform 1 unphosphorylated 7 (human) hCTNNB1/iso:1/UnPhos:7|UniProtKB:P35222-1, Thr-393, PR:000026291 enables GO:0005515 protein binding PR:Q9YGY0 PMID:19565571 IPI NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER Note=Binding between proteins from heterogeneous species PR:000044478 catenin beta-1 isoform 1 phosphorylated 13 (human) hCTNNB1/iso:1/Phos:13|UniProtKB:P35222-1, Tyr-654, MOD:00048 enables GO:0003713 transcription coactivator activity PMID:23640056 EXP NCBITaxon:9606 UniProtKB:P35222-1 20150113 PRO:KER PR:000044484 appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 (human) ghrelin-28 active form (human)|hGHRL/iso:1/ClvOOct:1|UniProtKB:Q9UBU3-1, 24-51, Ser-26, MOD:00295 acts_upstream_of_or_within GO:0097009 energy homeostasis MGI_ref:5474564|PMID:15591499 IDA NCBITaxon:10090 MGI:1930008 20150114 MGI:MGI PR:000044486 appetite-regulating hormone isoform 1 cleaved and non-octanoylated 1 (mouse) mGHRL/iso:1/ClvUnOOct:1|UniProtKB:Q9EQX0-1, 24-51, Ser-26, PR:000026291 acts_upstream_of_or_within GO:0097009 energy homeostasis MGI_ref:5474564|PMID:15591499 IDA NCBITaxon:10090 MGI:1930008 20150114 MGI:MGI PR:000044488 CEACAM1a-2S, signal peptide removed N-glycosylasparagine form (mouse) Bgp C glycosylated (mouse)|Bgp1/2S glycosylated (mouse)|BgpC glycosylated (mouse)|CEA-related cell adhesion molecule 1, isoform 1/2S glycosylated (mouse)|Ceacam1/D1,4S glycosylated (mouse)|CEACAM1a-2S glycosylated (mouse)|mCEACAM1a/iso:2S/SigPep-/NGlycoAsn+|UniProtKB:P31809-4, 35-278, MOD:00160 enables GO:0046790 virion binding MGI_ref:3053174|PMID:8380065 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ located_in GO:0016020 membrane MGI_ref:5608587|PMID:2164599 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI occurs_in(MA:0000358) PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ located_in GO:0016020 membrane MGI_ref:63233|PMID:8402684 IDA NCBITaxon:10090 MGI:1347245 20150128 MGI:MGI part_of(MA:0000335)|part_of(MA:0000358) PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ located_in GO:0016020 membrane MGI_ref:73162|PMID:1648219 IDA NCBITaxon:10090 MGI:1347245 20141229 MGI:MGI occurs_in(MA:0000358)|occurs_in(MA:0000337)|occurs_in(MA:0000335) PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ located_in GO:0031526 brush border membrane MGI_ref:73162|PMID:1648219 IDA NCBITaxon:10090 MGI:1347245 20141229 MGI:MGI occurs_in(MA:0000328) PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ acts_upstream_of_or_within GO:0044794 positive regulation by host of viral process MGI_ref:2148352|PMID:11483763 IMP NCBITaxon:10090 MGI_allele:2180785 MGI:1347245 20150102 MGI:MGI PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse) mCEACAM1a/iso:4/NGlycoAsp+ NOT enables GO:0001618 virus receptor activity MGI_ref:5608587|PMID:2164599 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI occurs_in(MA:0000358) PR:000044490 CEACAM1a-2 N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/NGlycoAsp+ located_in GO:0016020 membrane MGI_ref:5608587|PMID:2164599 IDA NCBITaxon:10090 MGI:1347245 20150123 MGI:MGI occurs_in(MA:0000358) PR:000044490 CEACAM1a-2 N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/NGlycoAsp+ located_in GO:0016020 membrane MGI_ref:63233|PMID:8402684 IDA NCBITaxon:10090 MGI:1347245 20141229 MGI:MGI occurs_in(MA:0000335)|occurs_in(MA:0000358) PR:000044490 CEACAM1a-2 N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/NGlycoAsp+ located_in GO:0031526 brush border membrane MGI_ref:73162|PMID:1648219 IDA NCBITaxon:10090 MGI:1347245 20150128 MGI:MGI occurs_in(MA:0000328) PR:000044490 CEACAM1a-2 N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/NGlycoAsp+ acts_upstream_of_or_within GO:0044793 negative regulation by host of viral process MGI_ref:2148352|PMID:11483763 IMP NCBITaxon:10090 MGI_allele:2180785 MGI:1347245 20150102 MGI:MGI PR:000044490 CEACAM1a-2 N-glycosylasparagine form (mouse) mCEACAM1a/iso:2/NGlycoAsp+ NOT enables GO:0001618 virus receptor activity MGI_ref:5608587|PMID:2164599 IDA NCBITaxon:10090 MGI:1347245 20150128 MGI:MGI occurs_in(MA:0000358) PR:000044494 heat shock protein HSP 90-alpha, initiator methionine removed and K63-polyubiquitinated 1 (mouse) mHSP90AA1 K63-Ub|mHSP90AA1 ubiquitinated|mHSP90AA1/InitMet-/K63polyUbiq:1 located_in GO:0005634 nucleus MGI_ref:5427282|PMID:22431752 IDA NCBITaxon:10090 MGI:96250 20150115 MGI:MGI occurs_in(EMAP:2735) PR:000044494 heat shock protein HSP 90-alpha, initiator methionine removed and K63-polyubiquitinated 1 (mouse) mHSP90AA1 K63-Ub|mHSP90AA1 ubiquitinated|mHSP90AA1/InitMet-/K63polyUbiq:1 located_in GO:0005737 cytoplasm MGI_ref:5427282|PMID:22431752 IDA NCBITaxon:10090 MGI:96250 20150115 MGI:MGI occurs_in(EMAP:2735) PR:000044495 thrombospondin-1, signal peptide removed form (mouse) mTHBS1/SigPep- located_in GO:0005615 extracellular space PMID:12498716 IDA NCBITaxon:10090 UniProtKB:P35441 20080301 PRO:CNA Note=Evidence on signal peptide removal is by curator inference based on PMID:8654563. PR:000044498 glycine receptor subunit alpha-3 isoform Alpha-3K (mouse) GlyR alpha3K|mGLRA3/iso:Alpha-3K acts_upstream_of_or_within GO:0072578 neurotransmitter-gated ion channel clustering MGI_ref:4365666|PMID:19723286 IGI NCBITaxon:10090 MGI:95751 MGI:95749 20150127 MGI:MGI occurs_in(CL:0002608) PR:000044498 glycine receptor subunit alpha-3 isoform Alpha-3K (mouse) GlyR alpha3K|mGLRA3/iso:Alpha-3K acts_upstream_of_or_within GO:0097112 gamma-aminobutyric acid receptor clustering MGI_ref:4365666|PMID:19723286 IGI NCBITaxon:10090 MGI:95751 MGI:95749 20150127 MGI:MGI occurs_in(CL:0002608) PR:000044501 CEACAM1b-4, signal peptide removed N-glycosylasparagine form (mouse) CEACAM1(b)-4 glycogylated (mouse)|Ceacam1b-4 glycogylated (mouse)|mCEACAM1b/iso:4/SigPep-/NGlycoAsn+ located_in GO:0031526 brush border membrane MGI_ref:73162|PMID:1648219 IDA NCBITaxon:10090 MGI:1347245 20150128 MGI:MGI occurs_in(MA:0000328) PR:000044502 CEACAM1a-C1, signal peptide removed N-glycosylasparagine form (mouse) mCEACAM1a/iso:C1/SigPep-/NGlycoAsn+ located_in GO:0005615 extracellular space MGI_ref:3848729|PMID:19358828 IDA NCBITaxon:10090 MGI:1347245 20150105 MGI:MGI occurs_in(MA:0001553) PR:000044506 tyrosine-protein kinase ABL1 phosphorylated 1 (human) hABL1/Phos:1|UniProtKB:P00519-1, Thr-735, MOD:00047 enables GO:0071889 14-3-3 protein binding PR:000044507 PMID:15696159|PMID:16888623 IPI NCBITaxon:9606 UniProtKB:P00519-1 20150226 PRO:CNA Source=eFIP PR:000044506 tyrosine-protein kinase ABL1 phosphorylated 1 (human) hABL1/Phos:1|UniProtKB:P00519-1, Thr-735, MOD:00047 enables GO:0071889 14-3-3 protein binding PR:P63104 PMID:15696159 IPI NCBITaxon:9606 UniProtKB:P00519-1 20150226 PRO:CNA Source=eFIP PR:000044506 tyrosine-protein kinase ABL1 phosphorylated 1 (human) hABL1/Phos:1|UniProtKB:P00519-1, Thr-735, MOD:00047 located_in GO:0005737 cytoplasm PMID:15696159 EXP NCBITaxon:9606 UniProtKB:P00519-1 20150226 PRO:CNA Source=eFIP PR:000044508 14-3-3 protein zeta/delta phosphorylated 1 (human) hYWHAZ/Phos:1|UniProtKB:P63104-1, Ser-184, MOD:00046 decreased enables GO:0005515 protein binding PR:000044509 PR:000044506 PMID:15696159 IPI NCBITaxon:9606 UniProtKB:P63104-1 20150226 PRO:CNA Source=eFIP PR:000044509 14-3-3 protein zeta/delta unphosphorylated 1 (human) hYWHAZ/UnPhos:1|UniProtKB:P63104-1, Ser-184, PR:000026291 enables GO:0005515 protein binding PR:000044506 PMID:15696159 IPI NCBITaxon:9606 UniProtKB:P63104-1 20150226 PRO:CNA Source=eFIP PR:000044510 catenin beta-1 isoform 1 phosphorylated 14 (human) hCTNNB1/iso:1/Phos:14|UniProtKB:P35222-1, Ser-552, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P63104 PMID:17287208 IPI NCBITaxon:9606 UniProtKB:P35222-1 20150226 PRO:CNA Source=eFIP PR:000044511 heat shock protein HSP 90-alpha, initiator methionine removed non-ubiquitinated 1 (mouse) mHSP90AA1 non-ubiquitinated|mHSP90AA1/InitMet-/UnUbiq:1 located_in GO:0032587 ruffle membrane MGI_ref:5427282|PMID:22431752 IDA NCBITaxon:10090 MGI:96250 20150115 MGI:MGI occurs_in(EMAP:2735) PR:000044513 voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 (mouse) mKCNA4/iso:1/Phos:1|UniProtKB:Q61423-1, Ser-122, MOD:00046 located_in GO:0014069 postsynaptic density PMID:18056256 IDA NCBITaxon:10090 UniProtKB:Q61423-1 20080601 PRO:CNA PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse) mIL6R/iso:1/Clv:soluble enables GO:0004915 interleukin-6 receptor activity PMID:8477802 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse) mIL6R/iso:1/Clv:soluble enables GO:0019981 interleukin-6 binding PMID:8477802 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse) mIL6R/iso:1/Clv:soluble located_in GO:0005615 extracellular space PMID:8477802 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse) mIL6R/iso:1/Clv:soluble acts_upstream_of_or_within GO:0070102 interleukin-6-mediated signaling pathway PMID:8477802 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:000044551 presenilin-1 sequence variant F386I (human) hPSEN1/var:F386I|UniProtKB:P49768-1, Phe-386, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f386i EXP NCBITaxon:9606 Alzforum:psen1-f386i 20180510 PRO:DAN PR:000044552 presenilin-1 sequence variant F388L (human) hPSEN1/var:F388L|UniProtKB:P49768-1, Phe-388, CHEBI:30006 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-f388l EXP NCBITaxon:9606 Alzforum:psen1-f388l 20180510 PRO:DAN PR:000044553 presenilin-1 sequence variant G209A (human) hPSEN1/var:G209A|UniProtKB:P49768-1, Gly-209, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-g209a EXP NCBITaxon:9606 Alzforum:psen1-g209a 20180510 PRO:DAN PR:000044554 presenilin-1 sequence variant H214N (human) hPSEN1/var:H214N|UniProtKB:P49768-1, His-214, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-h214n EXP NCBITaxon:9606 Alzforum:psen1-h214n 20180510 PRO:DAN PR:000044555 presenilin-1 sequence variant I408T (human) hPSEN1/var:I408T|UniProtKB:P49768-1, Ile-408, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i408t EXP NCBITaxon:9606 Alzforum:psen1-i408t 20180510 PRO:DAN PR:000044556 presenilin-1 sequence variant N135Y (human) hPSEN1/var:N135Y|UniProtKB:P49768-1, Asn-135, CHEBI:46858 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-n135y EXP NCBITaxon:9606 Alzforum:psen1-n135y 20180510 PRO:DAN PR:000044557 presenilin-1 sequence variant P267A (human) hPSEN1/var:P267A|UniProtKB:P49768-1, Pro-267, CHEBI:46217 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-p267a EXP NCBITaxon:9606 Alzforum:psen1-p267a 20180510 PRO:DAN PR:000044558 presenilin-1 sequence variant R220P (human) hPSEN1/var:R220P|UniProtKB:P49768-1, Arg-220, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r220p EXP NCBITaxon:9606 Alzforum:psen1-r220p 20180510 PRO:DAN PR:000044559 presenilin-1 sequence variant S169del (human) hPSEN1/var:S169del|UniProtKB:P49768-1, 1-168, 171-467 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s169del-%CE%B4s169 EXP NCBITaxon:9606 Alzforum:psen1-s169del-%CE%B4s169 20180510 PRO:DAN PR:000044560 presenilin-2 sequence variant G212V (human) hPSEN2/var:G212V|UniProtKB:P49810-1, Gly-212, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-g212v EXP NCBITaxon:9606 Alzforum:psen2-g212v 20180510 PRO:DAN PR:000044561 presenilin-2 sequence variant L238P (human) hPSEN2/var:L238P|UniProtKB:P49810-1, Leu-238, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-l238p EXP NCBITaxon:9606 Alzforum:psen2-l238p 20180510 PRO:DAN PR:000044570 triggering receptor expressed on myeloid cells 2 sequence variant D134G (human) hTREM2/var:D134G|UniProtKB:Q9NZC2-1, Asp-134, CHEBI:29947 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-d134g EXP NCBITaxon:9606 Alzforum:trem2-d134g 20180510 PRO:DAN PR:000044583 triggering receptor expressed on myeloid cells 2 sequence variant K186N (human) hTREM2/var:K186N|UniProtKB:Q9NZC2-1, Lys-186, CHEBI:50347 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-k186n EXP NCBITaxon:9606 Alzforum:trem2-k186n 20180510 PRO:DAN PR:000044586 Rho-associated protein kinase 1 isoform 1 unmodified form (human) hROCK1/iso:1/UnMod enables GO:0004674 protein serine/threonine kinase activity PMID:11283607 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20151104 PRO:CNA PR:000044586 Rho-associated protein kinase 1 isoform 1 unmodified form (human) hROCK1/iso:1/UnMod enables GO:0004674 protein serine/threonine kinase activity PMID:15699075 IDA NCBITaxon:9606 UniProtKB:O75116-1 20151104 PRO:CNA PR:000044604 triggering receptor expressed on myeloid cells 2 sequence variant V126G (human) hTREM2/var:V126G|UniProtKB:Q9NZC2-1, Val-126, CHEBI:29947 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-v126g EXP NCBITaxon:9606 Alzforum:trem2-v126g 20180510 PRO:DAN PR:000044607 triggering receptor expressed on myeloid cells 2 sequence variant W44* (human) hTREM2/var:W44*|TREM2 W44X (human)|UniProtKB:Q9NZC2, 1-43 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-w44x EXP NCBITaxon:9606 Alzforum:trem2-w44x 20180510 PRO:DAN PR:000044608 triggering receptor expressed on myeloid cells 2 sequence variant W50C (human) hTREM2/var:W50C|UniProtKB:Q9NZC2, Trp-50, CHEBI:29950|UniProtKB:Q9NZC2-1, Trp-50, CHEBI:29950 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-w50c EXP NCBITaxon:9606 Alzforum:trem2-w50c 20180510 PRO:DAN PR:000044609 triggering receptor expressed on myeloid cells 2 sequence variant W78* (human) hTREM2/var:W78*|TREM2 W78X (human)|UniProtKB:Q9NZC2, 1-77|UniProtKB:Q9NZC2-1, 1-77 associated_with_disease_progression DOID:0090112 Nasu-Hakola disease Alzforum:trem2-w78x EXP NCBITaxon:9606 Alzforum:trem2-w78x 20180510 PRO:DAN PR:000044708 voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human) hKCNA3/iso:1/UnMod enables GO:0015271 outward rectifier potassium channel activity PMID:9989602 EXP NCBITaxon:9606 UniProtKB:P22001-1 20090717 PRO:CL PR:000044746 Bcl-2-like protein 11 isoform 2 unmodified form (human) hBCL2L11/iso:2/UnMod enables GO:0005515 protein binding PR:Q96QB1 PMID:12591950 IPI NCBITaxon:9606 UniProtKB:O43521-2 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod enables GO:0005515 protein binding PR:P04049 PMID:17011751 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod enables GO:0005515 protein binding PR:P06803-2 PMID:15280015 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod enables GO:0005515 protein binding PR:P15056 PMID:17011751 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod enables GO:0005515 protein binding PR:Q04759 PMID:17011751 IPI NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod located_in GO:0031966 mitochondrial membrane PMID:15280015 EXP NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse) mBAD/iso:1/UnMod acts_upstream_of_or_within GO:0006915 apoptotic process PMID:15280015 EXP NCBITaxon:10090 UniProtKB:Q61337-1 20090918 PRO:JAN PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat) rBAD/iso:1/UnMod enables GO:0005515 protein binding PR:P53563-1 PMID:10195903 IPI NCBITaxon:10116 UniProtKB:O35147-1 20090810 PRO:JAN Evidence=Treatment with L-Glutamate induces dephosphorylation and binding to BCL-XL. Evidence=Fig4B. PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat) rBAD/iso:1/UnMod located_in GO:0005739 mitochondrion PMID:10195903 EXP NCBITaxon:10116 UniProtKB:O35147-1 20090810 PRO:JAN PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat) rBAD/iso:1/UnMod decreased enables GO:0019902 phosphatase binding PR:000026134 PR:P63329 PMID:10195903 IPI NCBITaxon:10116 UniProtKB:O35147-1 20090810 PRO:JAN PR:000044749 Bcl2-associated agonist of cell death isoform 2 unmodified form (human) hBAD/iso:2/UnMod enables GO:0005515 protein binding PR:Q07817-1 PMID:10195903 IPI NCBITaxon:9606 UniProtKB:Q92934-1 20090810 PRO:JAN PR:000044749 Bcl2-associated agonist of cell death isoform 2 unmodified form (human) hBAD/iso:2/UnMod located_in GO:0005739 mitochondrion PMID:10195903 EXP NCBITaxon:9606 UniProtKB:Q92934-1 20090810 PRO:JAN PR:000044757 M protein (Dengue virus 2 Thailand/16681/84) M (DEN26)|PRO_0000037927|UniProtKB:P29990, 206-280 located_in GO:0019031 viral envelope PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044757 M protein (Dengue virus 2 Thailand/16681/84) M (DEN26)|PRO_0000037927|UniProtKB:P29990, 206-280 acts_upstream_of_or_within GO:0006955 immune response PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944) NS1 (DEN2N)|PRO_0000037962, Asn-905/Asn-982, MOD:00160|UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160 part_of GO:0019034 viral replication complex PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944) NS1 (DEN2N)|PRO_0000037962, Asn-905/Asn-982, MOD:00160|UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160 acts_upstream_of_or_within GO:0019079 viral genome replication PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944) NS1 (DEN2N)|PRO_0000037962, Asn-905/Asn-982, MOD:00160|UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160 acts_upstream_of_or_within GO:0097281 immune complex formation PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944) NS2A (DEN2N)|PRO_0000037963|UniProtKB:P14340, 1128-1345 part_of GO:0019034 viral replication complex PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944) NS2A (DEN2N)|PRO_0000037963|UniProtKB:P14340, 1128-1345 acts_upstream_of_or_within GO:0019068 virion assembly PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944) NS2A (DEN2N)|PRO_0000037963|UniProtKB:P14340, 1128-1345 acts_upstream_of_or_within GO:0019076 viral release from host cell PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944) NS2A (DEN2N)|PRO_0000037963|UniProtKB:P14340, 1128-1345 acts_upstream_of_or_within GO:0019079 viral genome replication PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84) NS2A (DEN26)|PRO_0000037930|UniProtKB:P29990, 1128-1345 acts_upstream_of_or_within GO:0060339 negative regulation of type I interferon-mediated signaling pathway PMID:14612562 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944) NS2B (DEN2N)|PRO_0000037964|UniProtKB:P14340, 1346-1475 acts_upstream_of_or_within GO:1900005 positive regulation of serine-type endopeptidase activity PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944) NS2B (DEN2N)|PRO_0000037964|UniProtKB:P14340, 1346-1475 contributes_to enables GO:0008236 serine-type peptidase activity PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES Target=PR:000036828. PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944) NS3 (DEN2N)|PRO_0000037965|UniProtKB:P14340, 1476-2093 enables GO:0003724 RNA helicase activity PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944) NS3 (DEN2N)|PRO_0000037965|UniProtKB:P14340, 1476-2093 enables GO:0008236 serine-type peptidase activity PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944) NS3 (DEN2N)|PRO_0000037965|UniProtKB:P14340, 1476-2093 enables GO:0017111 ribonucleoside triphosphate phosphatase activity PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944) NS3 (DEN2N)|PRO_0000037965|UniProtKB:P14340, 1476-2093 acts_upstream_of_or_within GO:0019082 viral protein processing PMID:10744671 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944) NS4A (DEN2N)|PRO_0000037966|UniProtKB:P14340, 2094-2220 part_of GO:0019034 viral replication complex PMID:17276984 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944) NS4A (DEN2N)|PRO_0000037966|UniProtKB:P14340, 2094-2220 acts_upstream_of_or_within GO:0019079 viral genome replication PMID:17276984 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84) NS4A (DEN26)|PRO_0000037933|UniProtKB:P29990, 2094-2220 acts_upstream_of_or_within GO:0060339 negative regulation of type I interferon-mediated signaling pathway PMID:14612562 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944) 2K (DEN2N)|PRO_0000261391|UniProtKB:P14340, 2221-2243 enables GO:0043495 protein-membrane adaptor activity PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944) 2K (DEN2N)|PRO_0000261391|UniProtKB:P14340, 2221-2243 located_in GO:0016020 membrane PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944) 2K (DEN2N)|PRO_0000261391|UniProtKB:P14340, 2221-2243 acts_upstream_of_or_within GO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence PMID:17276984 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944) NS4B (DEN2N)|PRO_0000037967|UniProtKB:P14340, 2244-2491 part_of GO:0019034 viral replication complex PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944) NS4B (DEN2N)|PRO_0000037967|UniProtKB:P14340, 2244-2491 acts_upstream_of_or_within GO:0019079 viral genome replication PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84) NS4B (DEN26)|PRO_0000037934|UniProtKB:P29990, 2244-2491 acts_upstream_of_or_within GO:0039563 symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity PMID:14612562 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 enables GO:0003968 RNA-dependent RNA polymerase activity PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 enables GO:0008168 methyltransferase activity PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 enables GO:0070568 guanylyltransferase activity PMID:23408612 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 part_of GO:0019034 viral replication complex PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 acts_upstream_of_or_within GO:0001510 RNA methylation PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 acts_upstream_of_or_within GO:0019079 viral genome replication PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944) NS5 (DEN2N)|PRO_0000037968|UniProtKB:P14340, 2492-3391 acts_upstream_of_or_within GO:0042783 evasion of host immune response PMID:21810535 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044769 prM (Dengue virus 2 Thailand/16681/84) prM (DEN26)|PRO_0000264673, Asn-183, MOD:00160|UniProtKB:P29990, 115-280, Asn-183, MOD:00160 enables GO:0044183 protein folding chaperone PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044769 prM (Dengue virus 2 Thailand/16681/84) prM (DEN26)|PRO_0000264673, Asn-183, MOD:00160|UniProtKB:P29990, 115-280, Asn-183, MOD:00160 acts_upstream_of_or_within GO:0019068 virion assembly PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044769 prM (Dengue virus 2 Thailand/16681/84) prM (DEN26)|PRO_0000264673, Asn-183, MOD:00160|UniProtKB:P29990, 115-280, Asn-183, MOD:00160 acts_upstream_of_or_within GO:0015031 protein transport PMID:14963133 EXP NCBITaxon:31634 UniProtKB:P29990 20130711 PRO:ES PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944) prM (DEN2N)|PRO_0000261389, Asn-183, MOD:00160|UniProtKB:P14340, 115-280, Asn-183, MOD:00160 located_in GO:0019031 viral envelope PMID:8429301 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944) prM (DEN2N)|PRO_0000261389, Asn-183, MOD:00160|UniProtKB:P14340, 115-280, Asn-183, MOD:00160 acts_upstream_of_or_within GO:0006955 immune response PMID:8429301 EXP NCBITaxon:11065 UniProtKB:P14340 20130711 PRO:ES PR:000044787 thrombospondin-2 isoform 1 cleaved 2 (human) hTHBS2/iso:1/Clv:2|UniProtKB:P35442-1, 19-306 located_in GO:0005615 extracellular space PMID:17082774 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000044787 thrombospondin-2 isoform 1 cleaved 2 (human) hTHBS2/iso:1/Clv:2|UniProtKB:P35442-1, 19-306 acts_upstream_of_or_within GO:0016525 negative regulation of angiogenesis PMID:17082774 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000044787 thrombospondin-2 isoform 1 cleaved 2 (human) hTHBS2/iso:1/Clv:2|UniProtKB:P35442-1, 19-306 acts_upstream_of_or_within GO:0060055 angiogenesis involved in wound healing PMID:17082774 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000044788 thrombospondin-2 isoform 1 cleaved 3 (human) hTHBS2/iso:1/Clv:3|UniProtKB:P35442-1, 307-1172 acts_upstream_of_or_within GO:0016525 negative regulation of angiogenesis PMID:17082774 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000044788 thrombospondin-2 isoform 1 cleaved 3 (human) hTHBS2/iso:1/Clv:3|UniProtKB:P35442-1, 307-1172 acts_upstream_of_or_within GO:0060055 angiogenesis involved in wound healing PMID:17082774 IDA NCBITaxon:9606 UniProtKB:P35442-1 20080301 PRO:CNA PR:000044791 envelope glycoprotein gp120 N-glycosylated 1 (Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF)) HIV1(JRCSF)-env/Clv:gp120/NGlyco:1|UniProtKB:P20871, 31-503, Asn-195/Asn-228/Asn-239/Asn-260/Asn-293/Asn-299/Asn-329/Asn-336/Asn-382/Asn-388/Asn-392, MOD:00160 enables GO:0005515 protein binding PR:Q9NNX6 PMID:12438611 IPI NCBITaxon:11688 UniProtKB:P20871-1 20090918 PRO:CNA Note=DC-SIGN seems critical for whether HIV is bound and targeted to the endolysosomal pathway PR:000044810 eIF-2-alpha kinase GCN2 isoform 1 phosphorylated form (mouse) GCN2beta phosphorylated 1 (mouse)|mEIF2AK4/iso:1/PhosRes+|UniProtKB:Q9QZ05-1, MOD:00696 located_in GO:0005622 intracellular anatomical structure MGI_ref:3823138|PMID:18996085 IDA NCBITaxon:10090 MGI:97858 MGI:1353427 20150413 MGI:MGI part_of(CL:0000023) PR:000044814 cytokine receptor common subunit beta isoform 1 phosphorylated 1 (human) Bc phosphorylated 1 (human)|beta c phosphorylated 1 (human)|CSF2RB isoform 1 phosphorylated 1 (human)|hCSF2RB/iso:1/Phos:1|UniProtKB:P32927-1, Ser-601, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P63104 PMID:10477722 IPI NCBITaxon:9606 UniProtKB:P32927-1 20150504 PRO:CNA PR:000044815 F-box only protein 4 isoform 1 phosphorylated 1 (human) FBXO4 isoform 1 phosphorylated 1 (human)|hFBXO4/iso:1/Phos:1|UniProtKB:Q9UKT5-1, Ser-12, MOD:00046 enables GO:0042803 protein homodimerization activity PMID:18598945|PMID:21242966 IDA NCBITaxon:9606 UniProtKB:Q9UKT5-1 20150504 PRO:CNA PR:000044815 F-box only protein 4 isoform 1 phosphorylated 1 (human) FBXO4 isoform 1 phosphorylated 1 (human)|hFBXO4/iso:1/Phos:1|UniProtKB:Q9UKT5-1, Ser-12, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P62260 PMID:21242966 IPI NCBITaxon:9606 UniProtKB:Q9UKT5-1 20150504 PRO:CNA Note=Binding between proteins from heterogeneous species PR:000044816 kinase suppressor of Ras 1 phosphorylated 1 (mouse) KSR phosphorylated 1 (mouse)|mKSR1/Phos:1|UniProtKB:Q61097-1, Ser-297/Ser-392, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:000003237 PMID:9858547 IPI NCBITaxon:10090 UniProtKB:Q61097-1 20150504 PRO:CNA PR:000044817 phosphofurin acidic cluster sorting protein 2 phosphorylated 1 (human) hPACS2/Phos:1|PACS-2 phosphorylated 1 (human)|PACS2 phosphorylated 1 (human)|UniProtKB:Q86VP3-1, Ser-437, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:000044507 PMID:19481529 IPI NCBITaxon:9606 UniProtKB:Q86VP3-1 20150504 PRO:CNA Note=Evidence in Fig5D PR:000044818 serine/threonine-protein kinase PLK1 phosphorylated 1 (human) hPLK1/Phos:1|UniProtKB:P53350, Ser-99, MOD:00046|Thr-210, MOD:00047 enables GO:0071889 14-3-3 protein binding PR:P61981 PMID:23695676 IPI NCBITaxon:9606 UniProtKB:P53350-1 20150504 PRO:CNA PR:000044818 serine/threonine-protein kinase PLK1 phosphorylated 1 (human) hPLK1/Phos:1|UniProtKB:P53350, Ser-99, MOD:00046|Thr-210, MOD:00047 acts_upstream_of_or_within GO:0007091 metaphase/anaphase transition of mitotic cell cycle PMID:23695676 EXP NCBITaxon:9606 UniProtKB:P53350-1 20150504 PRO:CNA PR:000044819 serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human) hPAK4/iso:1/Phos:1|UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046 enables GO:0071889 14-3-3 protein binding PR:P61981 PMID:23695676 IPI NCBITaxon:9606 UniProtKB:O96013-1 20150504 PRO:CNA PR:000044819 serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human) hPAK4/iso:1/Phos:1|UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046 located_in GO:0031252 cell leading edge PMID:23695676 EXP NCBITaxon:9606 UniProtKB:O96013-1 20150504 PRO:CNA Note=Evidence in Fig2 PR:000044821 neuregulin-1 type I-beta1a mature form (mouse) mNRG1/iso:Ibeta1a/mature|neuregulin beta1a mature form (mouse)|NRG beta1a mature form (mouse) located_in GO:0005576 extracellular region MGI_ref:3625788|PMID:11116142 IDA NCBITaxon:10090 MGI:96083 20150514 MGI:MGI occurs_in(CL:0000187) PR:000044821 neuregulin-1 type I-beta1a mature form (mouse) mNRG1/iso:Ibeta1a/mature|neuregulin beta1a mature form (mouse)|NRG beta1a mature form (mouse) acts_upstream_of_or_within GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:3625788|PMID:11116142 IDA NCBITaxon:10090 MGI:96083 20150514 MGI:MGI occurs_in(CL:0000187),has_direct_input(UniProtKB:P70424)|occurs_in(CL:0000187),has_direct_input(UniProtKB:Q61526) PR:000044824 neuregulin-1 type III-beta1a transmembrane precursor (mouse) mNRG1/iso:IIIbeta1a/precursor|neuregulin type III-beta1a precursor (mouse)|NRG type III-beta1a precursor (mouse) acts_upstream_of_or_within GO:0045773 positive regulation of axon extension MGI_ref:4461331|PMID:20610754 IMP NCBITaxon:10090 MGI:96083 20150611 MGI:MGI occurs_in(CL:0002609) PR:000044826 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 1 (human) hPDHA1/TransPep-/Phos:1|PRO_0000020440, Ser-232, MOD:00046|UniProtKB:P08559-1, 31-390, Ser-232, MOD:00046 NOT enables GO:0004738 pyruvate dehydrogenase activity PMID:11092882|PMID:7782287 IDA NCBITaxon:9606 UniProtKB:P08559-1 20150520 PRO:AE PR:000044827 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 2 (human) hPDHA1/TransPep-/Phos:2|PRO_0000020440, Ser-293, MOD:00046|UniProtKB:P08559-1, 31-390, Ser-293, MOD:00046 NOT enables GO:0004738 pyruvate dehydrogenase activity PMID:11092882|PMID:7782287 IDA NCBITaxon:9606 UniProtKB:P08559-1 20150520 PRO:AE PR:000044828 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 3 (human) hPDHA1/TransPep-/Phos:3|PRO_0000020440, Ser-300, MOD:00046|UniProtKB:P08559-1, 31-390, Ser-300, MOD:00046 NOT enables GO:0004738 pyruvate dehydrogenase activity PMID:11092882|PMID:7782287 IDA NCBITaxon:9606 UniProtKB:P08559-1 20150520 PRO:AE PR:000044829 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial inactive (human) hPDHA1/TransPep-/Phos:[123] NOT enables GO:0004738 pyruvate dehydrogenase activity PMID:11092882|PMID:7782287 IDA NCBITaxon:9606 20150520 PRO:AE PR:000044830 catalase-3 phosphorylated 1 (Arabidopsis thaliana) At-CAT3(chr1)/Phos:1|AtCAT3 phosphorylated|UniProtKB:Q42547-1, Ser-261, MOD:00046 acts_upstream_of_or_within GO:0042631 cellular response to water deprivation PMID:25966761 IDA NCBITaxon:3702 UniProtKB:Q42547-1 20150520 PRO:CNA PR:000044830 catalase-3 phosphorylated 1 (Arabidopsis thaliana) At-CAT3(chr1)/Phos:1|AtCAT3 phosphorylated|UniProtKB:Q42547-1, Ser-261, MOD:00046 increased enables GO:0004096 catalase activity PR:000044831 PMID:25966761 IDA NCBITaxon:3702 UniProtKB:Q42547-1 20150520 PRO:CNA PR:000044836 NAD(P)H-hydrate epimerase isoform 2 (mouse) AD(P)H-hydrate epimerase precursor short form (mouse)|cAIBP (mouse)|mNAXE/iso:2|UniProtKB:Q8K4Z3, 46-282|UniProtKB:Q8K4Z3-1, 46-282 located_in GO:0005634 nucleus MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:2180167 20150603 MGI:MGI PR:000044836 NAD(P)H-hydrate epimerase isoform 2 (mouse) AD(P)H-hydrate epimerase precursor short form (mouse)|cAIBP (mouse)|mNAXE/iso:2|UniProtKB:Q8K4Z3, 46-282|UniProtKB:Q8K4Z3-1, 46-282 located_in GO:0005829 cytosol MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:2180167 20150603 MGI:MGI PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] located_in GO:0030424 axon MGI_ref:3042336|PMID:15044753 IDA NCBITaxon:10090 MGI:96083 20150318 MGI:MGI part_of(CL:0000540),occurs_in(MA:0001172) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] located_in GO:0030424 axon MGI_ref:4461331|PMID:20610754 IDA NCBITaxon:10090 MGI:96083 20150609 MGI:MGI part_of(CL:0002609) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] located_in GO:0030425 dendrite MGI_ref:4461331|PMID:20610754 IDA NCBITaxon:10090 MGI:96083 20150609 MGI:MGI part_of(CL:0002609) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] located_in GO:0030673 axolemma MGI_ref:3796800|PMID:18458158 IDA NCBITaxon:10090 MGI:96083 20150604 MGI:MGI part_of(CL:0000101) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] located_in GO:0044297 cell body MGI_ref:4461331|PMID:20610754 IDA NCBITaxon:10090 MGI:96083 20150609 MGI:MGI part_of(CL:0002609) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0001964 startle response MGI_ref:3803029|PMID:18596162 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150608 MGI:MGI PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0008366 axon ensheathment MGI_ref:3590355|PMID:16129398 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150318 MGI:MGI occurs_in(CL:0000540) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:3796800|PMID:18458158 IGI NCBITaxon:10090 MGI:104771 MGI:96083 20150604 MGI:MGI occurs_in(CL:0000101) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0031643 positive regulation of myelination MGI_ref:3590355|PMID:16129398 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150318 MGI:MGI occurs_in(CL:0000540) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0031643 positive regulation of myelination MGI_ref:4420197|PMID:18080294 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150608 MGI:MGI occurs_in(MA:0000168) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0060999 positive regulation of dendritic spine development MGI_ref:3803029|PMID:18596162 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150608 MGI:MGI occurs_in(CL:1001571),occurs_in(MA:0000960) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:0060999 positive regulation of dendritic spine development MGI_ref:4461331|PMID:20610754 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150609 MGI:MGI occurs_in(CL:0002609)|occurs_in(CL:0002609) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] acts_upstream_of_or_within GO:2000010 positive regulation of protein localization to cell surface MGI_ref:3796800|PMID:18458158 IGI NCBITaxon:10090 MGI:104771 MGI:96083 20150604 MGI:MGI occurs_in(CL:0000101),regulates_o_has_participant(UniProtKB:P49582) PR:000044840 neuregulin-1 type III (mouse) mNRG1/iso:IIIbeta[1a/1c/3] NOT acts_upstream_of_or_within GO:0048709 oligodendrocyte differentiation MGI_ref:4420197|PMID:18080294 IMP NCBITaxon:10090 MGI_allele:1928831 MGI:96083 20150608 MGI:MGI PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 enables GO:0005515 protein binding PR:O54941 MGI_ref:4438553|PMID:19781646 IPI NCBITaxon:10090 MGI:96083 20150629 MGI:MGI occurs_in(CL:0000047) PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 located_in GO:0005634 nucleus MGI_ref:4461331|PMID:20610754 IDA NCBITaxon:10090 MGI:96083 20150610 MGI:MGI part_of(CL:0002609) PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 acts_upstream_of_or_within GO:0022008 neurogenesis MGI_ref:4438553|PMID:19781646 IGI NCBITaxon:10090 MGI:96083 MGI:96083 20150629 MGI:MGI occurs_in(CL:0000047) PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 acts_upstream_of_or_within GO:0022008 neurogenesis MGI_ref:4438553|PMID:19781646 IMP NCBITaxon:10090 MGI:96083 20150629 MGI:MGI occurs_in(CL:0000047) PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4461331|PMID:20610754 IMP NCBITaxon:10090 MGI:96083 20150610 MGI:MGI occurs_in(CL:0002609) PR:000044843 neuregulin-1 intracellular domain (mouse) mNRG1/Clv:intracellular|NRG1 ICD (mouse)|UniProtKB:Q6DR99, 326-700 NOT acts_upstream_of_or_within GO:0045773 positive regulation of axon extension MGI_ref:4461331|PMID:20610754 IMP NCBITaxon:10090 MGI:96083 20150611 MGI:MGI occurs_in(CL:0002609) PR:000044878 histone H1.4, initiator methionine removed monomethylated 1 (human) H1.4:H1K25me1|hHIST1H1E/InitMet-/Me1:1|PRO_0000195908, Lys-26, MOD:00085|UniProtKB:P10412, 2-219, Lys-26, MOD:00085 enables GO:0005515 protein binding PR:P45973 PMID:16127177 IPI NCBITaxon:9606 UniProtKB:P10412 20151112 PRO:CNA PR:000044898 histone H2A type 1-G/I/K/L/M, initiator methionine removed phosphorylated 2 (human) H2A_type_1:H2AT120ph|hHIST1H2A[G/I/K/L/M]/InitMet-/Phos:2|PRO_0000055235, Thr-121, MOD:00047|UniProtKB:P0C0S8, 2-130, Thr-121, MOD:00047 located_in GO:0000779 condensed chromosome, centromeric region PMID:19965387 EXP NCBITaxon:9606 UniProtKB:P0C0S8 20130117 PRO:KER PR:000044898 histone H2A type 1-G/I/K/L/M, initiator methionine removed phosphorylated 2 (human) H2A_type_1:H2AT120ph|hHIST1H2A[G/I/K/L/M]/InitMet-/Phos:2|PRO_0000055235, Thr-121, MOD:00047|UniProtKB:P0C0S8, 2-130, Thr-121, MOD:00047 increased acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PR:000035694 PMID:19965387 EXP NCBITaxon:9606 UniProtKB:P0C0S8 20130102 PRO:KER Target=PR:Q5FBB7. PR:000045368 DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (human) hID2/iso:1/UnPhos:1|UniProtKB:Q02363-1, Ser-5, PR:000026291 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:14627819|PMID:9029153 IDA NCBITaxon:9606 UniProtKB:Q02363-1 20151104 PRO:CNA PR:000045369 E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human) hSIAH1/iso:1/UnPhos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291 enables GO:0005515 protein binding PR:Q69ZI1 PMID:16230351 IPI NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20151104 PRO:CNA PR:000045369 E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human) hSIAH1/iso:1/UnPhos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291 acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process PMID:16230351 EXP NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20151104 PRO:CNA PR:000045369 E3 ubiquitin-protein ligase SIAH1 isoform 1 unphosphorylated 1 (human) hSIAH1/iso:1/UnPhos:1|UniProtKB:Q8IUQ4-1, Tyr-100/Tyr-126, PR:000026291 acts_upstream_of_or_within GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351 EXP NCBITaxon:9606 UniProtKB:Q8IUQ4-1 20151104 PRO:CNA PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 enables GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PMID:17254966 EXP NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:CNA PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 enables GO:0005515 protein binding PR:P31749 PMID:12244301 IPI NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:JAN PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 enables GO:0044877 protein-containing complex binding PR:000026741 PMID:17254966 IPI NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:CNA PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 located_in GO:0005634 nucleus PMID:12244301 EXP NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:JAN PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:12244301 EXP NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:JAN PR:000045370 cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human) hCDKN1B/iso:1/UnPhos:2|UniProtKB:P46527-1, Tyr-88, PR:000026291 acts_upstream_of_or_within GO:0051318 G1 phase PMID:17254966 EXP NCBITaxon:9606 UniProtKB:P46527-1 20151104 PRO:CNA PR:000045371 smad2 isoform Long unphosphorylated 1 (human) hSMAD2/iso:Long/UnPhos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291 enables GO:0005515 protein binding PMID:8980228 IPI NCBITaxon:9606 UniProtKB:Q15796-1 20151104 PRO:CNA PR:000045371 smad2 isoform Long unphosphorylated 1 (human) hSMAD2/iso:Long/UnPhos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291 located_in GO:0005737 cytoplasm PMID:15280432|PMID:17074053 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20151104 PRO:CNA PR:000045371 smad2 isoform Long unphosphorylated 1 (human) hSMAD2/iso:Long/UnPhos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291 located_in GO:0005769 early endosome PMID:12356868 IDA NCBITaxon:9606 UniProtKB:Q15796-1 20151104 PRO:CNA Note=When bound to PR:000002535 PR:000045371 smad2 isoform Long unphosphorylated 1 (human) hSMAD2/iso:Long/UnPhos:1|UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8752209 IDA NCBITaxon:9609 UniProtKB:Q15796-1 20151104 PRO:CNA PR:000045372 endonuclease 8-like 2 isoform 1 unacetylated 1 (human) endonuclease 8-like 2 isoform 1 unmodified form (human)|hNEIL2/iso:1/UnAc:1|UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, PR:000026291 enables GO:0019104 DNA N-glycosylase activity PMID:15175427 EXP NCBITaxon:9606 UniProtKB:Q969S2-1 20151104 PRO:CNA PR:000045373 DNA polymerase beta unacetylated 1 (human) DNA polymerase beta unmodified form (human)|hPOLB/UnAc:1|UniProtKB:P06746, Lys-72, PR:000026291 enables GO:0016829 lyase activity PMID:12453427 EXP NCBITaxon:9606 UniProtKB:P06746 20151104 PRO:CNA PR:000045373 DNA polymerase beta unacetylated 1 (human) DNA polymerase beta unmodified form (human)|hPOLB/UnAc:1|UniProtKB:P06746, Lys-72, PR:000026291 acts_upstream_of_or_within GO:0006284 base-excision repair PMID:12453427 EXP NCBITaxon:9606 UniProtKB:P06746 20151104 PRO:CNA PR:000045374 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 non-myristoylated 1 (mouse) mSH3TC2/iso:1/UnMyr:1|UniProtKB:Q80VA5-1, 2-1289, Gly-2, PR:000026291 located_in GO:0055037 recycling endosome PMID:19805030 EXP NCBITaxon:10090 UniProtKB:Q80VA5-1 20151104 PRO:HJD PR:000045374 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 non-myristoylated 1 (mouse) mSH3TC2/iso:1/UnMyr:1|UniProtKB:Q80VA5-1, 2-1289, Gly-2, PR:000026291 NOT located_in GO:0005886 plasma membrane MGI_ref:4366127|PMID:19805030 IDA NCBITaxon:10090 MGI:2444417 20151104 MGI:MGI PR:000045377 DNA-binding protein inhibitor ID-2 isoform 1 unphosphorylated 1 (rat) rID2/iso:1/UnPhos:1|UniProtKB:P41137-1, Ser-5, PR:000026291 located_in GO:0005737 cytoplasm PMID:11706002 IDA NCBITaxon:10116 UniProtKB:P41137-1 20151104 PRO:CNA PR:000045381 cGMP-gated cation channel alpha-1 isoform 1 unphosphorylated 1 (cow) cow-CNGA1/iso:1/UnPhos:1|UniProtKB:Q00194-1, Tyr-498, PR:000026291 enables GO:0030553 cGMP binding PMID:10366613 IDA NCBITaxon:9913 UniProtKB:Q00194-1 20151104 PRO:CNA PR:000045386 voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat) rKCNC1/iso:2/UnPhos:1|rKCNC1/iso:Long/UnPhos:1|UniProtKB:P25122-1, Ser-503, PR:000026291 contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:16595659 IDA NCBITaxon:10116 UniProtKB:P25122-1 20151104 PRO:CNA PR:000045387 voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human) hKCNC4/iso:2/UnPhos:1|UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291 contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PMID:1381835|PMID:7993631|PMID:9649584 EXP NCBITaxon:9606 UniProtKB:Q03721-2 20151104 PRO:CNA PR:000045389 voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse) mKCND2/iso:1/UnPhos:3|UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291 located_in GO:0009986 cell surface PMID:12829703|PMID:16251476 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20151104 PRO:CNA PR:000045390 voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse) mKCND2/iso:1/UnPhos:4|UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291 contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PMID:16251476 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20151104 PRO:CNA PR:000045392 voltage-gated potassium channel KCNH2 isoform A unglycosylated 1 (human) hKCNH2/iso:A/UnGlyco:1|UniProtKB:Q12809-1, Asn-598, PR:000026291 located_in GO:0009986 cell surface PMID:12063277 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20151104 PRO:CNA PR:000045393 voltage-gated potassium channel KCNH2 isoform A unphosphorylated form (human) hKCNH2/iso:A/PhosRes- contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10837251|PMID:9351446 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20151104 PRO:CNA PR:000045400 histone H1.4, initiator methionine removed monomethylated and phosphorylated 1 (human) H1.4:H1K25me1|H1.4:H1S26ph|hHIST1H1E/InitMet-/Me1Phos:1|UniProtKB:P10412, 2-219, Lys-26, MOD:00085|Ser-27, MOD:00046 NOT enables GO:0005515 protein binding PR:P45973 PMID:16127177 IPI NCBITaxon:9606 UniProtKB:P10412 20151112 PRO:CNA PR:000045432 microtubule-associated protein tau sequence variant S285R (human) hMAPT/var:S285R|UniProtKB:P10636-8, Ser-285, CHEBI:29952 associated_with_disease_progression DOID:678 progressive supranuclear palsy Alzforum:mapt-s285r EXP NCBITaxon:9606 Alzforum:mapt-s285r 20180510 PRO:DAN PR:000045448 presenilin-1 sequence variant I83T (human) hPSEN1/var:I83T|UniProtKB:P49768-1, Ile-83, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i83t EXP NCBITaxon:9606 Alzforum:psen1-i83t 20180510 PRO:DAN PR:000045451 presenilin-1 sequence variant T116R (human) hPSEN1/var:T116R|UniProtKB:P49768-1, Thr-116, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-t116r EXP NCBITaxon:9606 Alzforum:psen1-t116r 20180510 PRO:DAN PR:000045453 presenilin-1 sequence variant L134R (human) hPSEN1/var:L134R|UniProtKB:P49768-1, Leu-134, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l134r EXP NCBITaxon:9606 Alzforum:psen1-l134r 20180510 PRO:DAN PR:000045454 presenilin-1 sequence variant L150P (human) hPSEN1/var:L150P|UniProtKB:P49768-1, Leu-150, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l150p EXP NCBITaxon:9606 Alzforum:psen1-l150p 20180510 PRO:DAN PR:000045455 presenilin-1 sequence variant A164V (human) hPSEN1/var:A164V|UniProtKB:P49768-1, Ala-164, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a164v EXP NCBITaxon:9606 Alzforum:psen1-a164v 20180510 PRO:DAN PR:000045456 presenilin-1 sequence variant L166V (human) hPSEN1/var:L166V|UniProtKB:P49768-1, Leu-166, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l166v EXP NCBITaxon:9606 Alzforum:psen1-l166v 20180510 PRO:DAN PR:000045459 presenilin-1 sequence variant E184G (human) hPSEN1/var:E184G|UniProtKB:P49768-1, Glu-184, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e184g EXP NCBITaxon:9606 Alzforum:psen1-e184g 20180510 PRO:DAN PR:000045460 presenilin-1 sequence variant I202F (human) hPSEN1/var:I202F|UniProtKB:P49768-1, Ile-202, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i202f EXP NCBITaxon:9606 Alzforum:psen1-i202f 20180510 PRO:DAN PR:000045462 presenilin-1 sequence variant L226F (human) hPSEN1/var:L226F|UniProtKB:P49768-1, Leu-226, CHEBI:29997 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l226f EXP NCBITaxon:9606 Alzforum:psen1-l226f 20180510 PRO:DAN PR:000045463 presenilin-1 sequence variant S230R (human) hPSEN1/var:S230R|UniProtKB:P49768-1, Ser-230, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s230r EXP NCBITaxon:9606 Alzforum:psen1-s230r 20180510 PRO:DAN PR:000045464 presenilin-1 sequence variant S230I (human) hPSEN1/var:S230I|UniProtKB:P49768-1, Ser-230, CHEBI:30009 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s230i EXP NCBITaxon:9606 Alzforum:psen1-s230i 20180510 PRO:DAN PR:000045465 presenilin-1 sequence variant A231P (human) hPSEN1/var:A231P|UniProtKB:P49768-1, Ala-231, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a231p EXP NCBITaxon:9606 Alzforum:psen1-a231p 20180510 PRO:DAN PR:000045466 presenilin-1 sequence variant L235R (human) hPSEN1/var:L235R|UniProtKB:P49768-1, Leu-235, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l235r EXP NCBITaxon:9606 Alzforum:psen1-l235r 20180510 PRO:DAN PR:000045467 presenilin-1 sequence variant A246P (human) hPSEN1/var:A246P|UniProtKB:P49768-1, Ala-246, CHEBI:50342 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a246p EXP NCBITaxon:9606 Alzforum:psen1-a246p 20180510 PRO:DAN PR:000045468 presenilin-1 sequence variant L262V (human) hPSEN1/var:L262V|UniProtKB:P49768-1, Leu-262, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-l262v EXP NCBITaxon:9606 Alzforum:psen1-l262v 20180510 PRO:DAN PR:000045469 presenilin-1 sequence variant E273G (human) hPSEN1/var:E273G|UniProtKB:P49768-1, Glu-273, CHEBI:29947 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e273g EXP NCBITaxon:9606 Alzforum:psen1-e273g 20180510 PRO:DAN PR:000045470 presenilin-1 sequence variant E280K (human) hPSEN1/var:E280K|UniProtKB:P49768-1, Glu-280, CHEBI:29967 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-e280k EXP NCBITaxon:9606 Alzforum:psen1-e280k 20180510 PRO:DAN PR:000045472 presenilin-1 sequence variant R377W (human) hPSEN1/var:R377W|UniProtKB:P49768-1, Arg-377, CHEBI:29954 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-r377w EXP NCBITaxon:9606 Alzforum:psen1-r377w 20180510 PRO:DAN PR:000045473 presenilin-1 sequence variant S390N (human) hPSEN1/var:S390N|UniProtKB:P49768-1, Ser-390, CHEBI:50347 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-s390n EXP NCBITaxon:9606 Alzforum:psen1-s390n 20180510 PRO:DAN PR:000045474 presenilin-1 sequence variant A396T (human) hPSEN1/var:A396T|UniProtKB:P49768-1, Ala-396, CHEBI:30013 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-a396t EXP NCBITaxon:9606 Alzforum:psen1-a396t 20180510 PRO:DAN PR:000045475 presenilin-1 sequence variant I437V (human) hPSEN1/var:I437V|UniProtKB:P49768-1, Ile-437, CHEBI:30015 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen1-i437v EXP NCBITaxon:9606 Alzforum:psen1-i437v 20180510 PRO:DAN PR:000045479 presenilin-2 sequence variant K161R (human) hPSEN2/var:K161R|UniProtKB:P49810-1, Lys-161, CHEBI:29952 associated_with_disease_progression DOID:10652 Alzheimer's disease Alzforum:psen2-k161r EXP NCBITaxon:9606 Alzforum:psen2-k161r 20180510 PRO:DAN PR:000045544 breast cancer type 2 susceptibility protein phosphorylated 2 (human) hBRCA2/Phos:2|UniProtKB:P51587, Thr-3387, MOD:00047 decreased enables GO:0005515 protein binding PR:000045545 PR:Q06609 PMID:18317453 IPI NCBITaxon:9606 UniProtKB:P51587 20160808 PRO:CNA PR:000045754 dual specificity protein kinase TTK phosphorylated 1 (human) hTTK/Phos:1|UniProtKB:P33981-1, Thr-676, MOD:00047 enables GO:0004672 protein kinase activity PMID:18680479 EXP NCBITaxon:9606 UniProtKB:P33981-1 20170512 PRO:KER PR:000045754 dual specificity protein kinase TTK phosphorylated 1 (human) hTTK/Phos:1|UniProtKB:P33981-1, Thr-676, MOD:00047 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:18680479|PMID:19120698 EXP NCBITaxon:9606 UniProtKB:P33981-1 20170512 PRO:KER PR:000045754 dual specificity protein kinase TTK phosphorylated 1 (human) hTTK/Phos:1|UniProtKB:P33981-1, Thr-676, MOD:00047 acts_upstream_of_or_within GO:0051298 centrosome duplication PMID:17728254 EXP NCBITaxon:9606 UniProtKB:P33981-1 20170512 PRO:KER PR:000045754 dual specificity protein kinase TTK phosphorylated 1 (human) hTTK/Phos:1|UniProtKB:P33981-1, Thr-676, MOD:00047 acts_upstream_of_or_within GO:0071174 mitotic spindle checkpoint signaling PMID:18083840 EXP NCBITaxon:9606 UniProtKB:P33981-1 20170512 PRO:KER PR:000049133 ribosomal protein S6 kinase alpha-6 phosphorylated 1 (human) hRPS6KA6/Phos:1|UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047 increased enables GO:0004674 protein serine/threonine kinase activity PR:000049860 PMID:15632195 EXP NCBITaxon:9606 UniProtKB:Q9UK32 20170629 PRO:KER PR:000049766 sugar transport protein 13 phosphorylated 1 (Arabidopsis thaliana) At-MSS1/Phos:1|UniProtKB:Q94AZ2, Thr-485, MOD:00047 acts_upstream_of_or_within GO:0042742 defense response to bacterium PMID:27884939 EXP NCBITaxon:3702 PR:Q94AZ2 20161128 PRO:CNA PR:000049766 sugar transport protein 13 phosphorylated 1 (Arabidopsis thaliana) At-MSS1/Phos:1|UniProtKB:Q94AZ2, Thr-485, MOD:00047 increased enables GO:0015145 monosaccharide transmembrane transporter activity PR:000049767 PMID:27884939 EXP NCBITaxon:3702 PR:Q94AZ2 20161128 PRO:CNA PR:000049844 TTK activation loop phosphorylated form (human) hTTK/pActloop|UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047)|Ser-677, MOD:00046 enables GO:0004672 protein kinase activity PMID:18680479|PMID:19120698 EXP NCBITaxon:9606 UniProtKB:P33981 20170512 PRO:KER PR:000049844 TTK activation loop phosphorylated form (human) hTTK/pActloop|UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047)|Ser-677, MOD:00046 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:18680479|PMID:19120698 EXP NCBITaxon:9606 UniProtKB:P33981 20170512 PRO:KER PR:000049845 TTK activation loop and P+1 loop phosphorylated form (human) hTTK/p(Act-loop_P+1-loop)|UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047 or Ser-677, MOD:00046)|Thr-686, MOD:00047 enables GO:0004672 protein kinase activity PMID:19120698 EXP NCBITaxon:9606 UniProtKB:P33981 20170512 PRO:KER PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human) hPDGFRB/SigPep-/Phos:2|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048 enables GO:0004713 protein tyrosine kinase activity PMID:15994317|PMID:9642269 EXP NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human) hPDGFRB/SigPep-/Phos:2|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048 increased enables GO:0005515 protein binding PR:000049848 PR:P20936 PMID:1653029 IPI NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human) hPDGFRB/SigPep-/Phos:2|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048 increased acts_upstream_of_or_within GO:0018108 peptidyl-tyrosine phosphorylation PR:000049848 PMID:1653029|PMID:9642269 EXP NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human) hPDGFRB/SigPep-/Phos:3|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 decreased enables GO:0004713 protein tyrosine kinase activity PR:000049846 PMID:15271984 EXP NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human) hPDGFRB/SigPep-/Phos:3|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 decreased enables GO:0005515 protein binding PR:000049846 PR:O14745 PMID:15271984 IPI NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human) hPDGFRB/SigPep-/Phos:3|UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 decreased acts_upstream_of_or_within GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction PR:000049846 PMID:15271984 EXP NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human) hPDGFRB/SigPep-/UnPhos:2|UniProtKB:P09619-1, 33-1106, Tyr-857, PR:000026291 acts_upstream_of_or_within GO:0038083 peptidyl-tyrosine autophosphorylation PMID:9642269 EXP NCBITaxon:9606 UniProtKB:P09619 20170515 PRO:KER PR:000049849 epidermal growth factor receptor, signal peptide removed phosphorylated 3 (human) hEGFR/SigPep-/Phos:3|UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046 decreased enables GO:0004713 protein tyrosine kinase activity PR:000049850 PMID:10347170 EXP NCBITaxon:9606 UniProtKB:P00533 20170629 PRO:KER PR:000049849 epidermal growth factor receptor, signal peptide removed phosphorylated 3 (human) hEGFR/SigPep-/Phos:3|UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046 decreased enables GO:0005515 protein binding PR:000049850 PR:P00533 PMID:10347170 IPI NCBITaxon:9606 UniProtKB:P00533 20170629 PRO:KER PR:000049851 epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human) hEGFR/SigPep-/Phos:4|UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046 decreased enables GO:0004713 protein tyrosine kinase activity PR:000049852 PMID:10347170 EXP NCBITaxon:9606 UniProtKB:P00533 20170629 PRO:KER PR:000049853 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:1|UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047 located_in GO:0005737 cytoplasm PMID:9756933 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049853 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:1|UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047 located_in GO:0005886 plasma membrane PMID:9756933 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049853 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:1|UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047 increased enables GO:0004674 protein serine/threonine kinase activity PR:000049854 PMID:8749392 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:2|UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046 increased enables GO:0001786 phosphatidylserine binding PR:000049856 PMID:9218480 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:2|UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046 increased enables GO:0005509 calcium ion binding PR:000049856 PMID:9218480 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:2|UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046 increased located_in GO:0005737 cytoplasm PR:000049856 PMID:9756933 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human) hPRKCB/iso:Beta-II/InitMet-/Phos:2|UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046 increased acts_upstream_of_or_within GO:0006468 protein phosphorylation PR:000049856 PMID:8749392 EXP NCBITaxon:9606 UniProtKB:P05771-2 20170629 PRO:KER PR:000049857 protein kinase C theta type phosphorylated 4 (human) hPRKCQ/Phos:4|UniProtKB:Q04759-1, Ser-695, MOD:00046 increased enables GO:0004674 protein serine/threonine kinase activity PR:000049858 PMID:11772397|PMID:15364937|PMID:16252004 EXP NCBITaxon:9606 UniProtKB:Q04759 20170629 PRO:KER PR:000049938 DAZ-associated protein 1 acetylated 1 (human) hDAZAP1/Ac:1|Prrp K150 (human)|UniProtKB:Q96EP5-1, Lys-150, MOD:00064 located_in GO:0005634 nucleus PMID:22001406 IDA NCBITaxon:9606 20171102 PRO:CNA PR:A0FKC7 Toll/IL-1 recepter (TIR)-domain containing adapter inducing interferon beta (chicken) chick-TICAM1 located_in GO:0005829 cytosol Reactome:REACT_26995 EXP NCBITaxon:9031 UniProtKB:A0FKC7 20140513 PRO:VS PR:A2ABV5-1 mediator of RNA polymerase II transcription subunit 14 isoform 1 (mouse) mMED14/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1349442 20120523 MGI:MGI PR:A2AGH6-1 mediator of RNA polymerase II transcription subunit 12 isoform 1 (mouse) mMED12/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1926212 20120523 MGI:MGI PR:A2AJ88-1 patatin-like phospholipase domain-containing protein 7 isoform 1 (mouse) mPNPLA7/iso:1 enables GO:0004622 lysophospholipase activity MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2AJ88-1 patatin-like phospholipase domain-containing protein 7 isoform 1 (mouse) mPNPLA7/iso:1 located_in GO:0005783 endoplasmic reticulum MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2AJ88-2 patatin-like phospholipase domain-containing protein 7 isoform 2 (mouse) mPNPLA7/iso:2 enables GO:0004622 lysophospholipase activity MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2AJ88-2 patatin-like phospholipase domain-containing protein 7 isoform 2 (mouse) mPNPLA7/iso:2 located_in GO:0005783 endoplasmic reticulum MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2AJ88-3 patatin-like phospholipase domain-containing protein 7 isoform 3 (mouse) mNREV2|mPNPLA7/iso:3|neuropathy target esterase-related esterase splice variant 2 (mouse) located_in GO:0005783 endoplasmic reticulum MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2AJ88-3 patatin-like phospholipase domain-containing protein 7 isoform 3 (mouse) mNREV2|mPNPLA7/iso:3|neuropathy target esterase-related esterase splice variant 2 (mouse) NOT enables GO:0004622 lysophospholipase activity MGI_ref:5319290|PMID:22326266 IDA NCBITaxon:10090 MGI:2385325 20140207 MGI:MGI PR:A2ARP9 cation channel sperm-associated protein 2 (mouse) Catsper2|CatSper2 (mouse)|mCATSPER2 acts_upstream_of_or_within GO:0001539 cilium or flagellum-dependent cell motility PMID:14657366 IDA NCBITaxon:10090 UniProtKB:A2ARP9 20080601 PRO:CNA PR:A2ARP9 cation channel sperm-associated protein 2 (mouse) Catsper2|CatSper2 (mouse)|mCATSPER2 acts_upstream_of_or_within GO:0030317 flagellated sperm motility PMID:14657366|PMID:17174296|PMID:17227845 IDA NCBITaxon:10090 UniProtKB:A2ARP9 20080601 PRO:CNA PR:A2ARP9-1 cation channel sperm-associated protein 2 isoform m1 (mouse) mCATSPER2/iso:m1 located_in GO:0031514 motile cilium PMID:11675491|PMID:14657366 IDA NCBITaxon:10090 UniProtKB:A2ARP9-1 20080601 PRO:CNA PR:A2RTF1-1 cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse) mCATSPERB/iso:1 part_of GO:0032991 protein-containing complex PMID:17478420 IDA NCBITaxon:10090 PR:000002581 UniProtKB:A2RTF1-1 20080601 PRO:CNA PR:A3QQZ3 interleukin-24 isoform 2 (mouse) FISP cytokine variant FISP-sp (mouse)|mIL24/iso:2 located_in GO:0005783 endoplasmic reticulum MGI_ref:3821693|PMID:18708357 IDA NCBITaxon:10090 MGI:2135548 20121120 MGI:MGI PR:A3QQZ3 interleukin-24 isoform 2 (mouse) FISP cytokine variant FISP-sp (mouse)|mIL24/iso:2 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:3821693|PMID:18708357 IGI NCBITaxon:10090 UniProtKB:Q925S4-1 MGI:2135548 20130624 MGI:MGI PR:A3QQZ3 interleukin-24 isoform 2 (mouse) FISP cytokine variant FISP-sp (mouse)|mIL24/iso:2 acts_upstream_of_or_within GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MGI_ref:3821693|PMID:18708357 IGI NCBITaxon:10090 UniProtKB:Q925S4-1 MGI:2135548 20130624 MGI:MGI PR:A6P7M8 thyroglobulin isoform 2 (mouse) kidney Tg (mouse)|kTg (mouse)|mTG/iso:2 located_in GO:0005615 extracellular space MGI_ref:4365669|PMID:19716808 IDA NCBITaxon:10090 UniProtKB:A6P7M8 20140507 PRO:HJD PR:A8IK50 Purkinje cell protein 2 isoform 2 (mouse) mPCP2/iso:2|Ret-PCP2 (mouse) located_in GO:0043025 neuronal cell body MGI_ref:3817370|PMID:18768681 IDA NCBITaxon:10090 MGI:97508 20121114 MGI:MGI part_of(MA:0000276),part_of(CL:0000749) PR:A9P557 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 2 (mouse) GM-CSF receptor alpha subunit isoform 2 (mouse)|GM-CSF receptor alpha-chain isoform 2 (mouse)|GMRalpha isoform 2 (mouse)|mCSF2RA/iso:2 NOT acts_upstream_of_or_within GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:A9P558 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 3 (mouse) GM-CSF receptor alpha subunit isoform 3 (mouse)|GM-CSF receptor alpha-chain isoform 3 (mouse)|GMRalpha isoform 3 (mouse)|GMRalpha truncated isoform (mouse)|mCSF2RA/iso:3 NOT acts_upstream_of_or_within GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:B0BL87 CD14 molecule (chicken) chick-CD14 located_in GO:0005886 plasma membrane PMID:18761368 EXP NCBITaxon:9031 UniProtKB:B0BL87 20140513 PRO:CNA PR:B0BL87 CD14 molecule (chicken) chick-CD14 located_in GO:0009986 cell surface PMID:18761368 EXP NCBITaxon:9031 UniProtKB:B0BL87 20140718 PRO:CNA Note=Figs.4 and Fig.5. PR:B2RSN1 c-myc protein isoform 2 (mouse) mMYC/iso:2 part_of GO:0005667 transcription factor complex PMID:7958908 IDA NCBITaxon:10090 UniProtKB:P28574 UniProtKB:B2RSN1 20080301 PRO:CNA PR:B2RSN1 c-myc protein isoform 2 (mouse) mMYC/iso:2 contributes_to enables GO:0003700 DNA-binding transcription factor activity PMID:7958908 IDA NCBITaxon:10090 UniProtKB:B2RSN1 20080301 PRO:CNA PR:B2ZEZ5 selection and upkeep of intraepithelial T-cells protein 2 isoform 4 (mouse) B7S3L (mouse)|mSkint2/iso:4 located_in GO:0005886 plasma membrane MGI_ref:3830586|PMID:17339463 IDA NCBITaxon:10090 MGI:3649629 20150528 MGI:MGI PR:B4YDY0 small conductance calcium-activated potassium channel protein 2 isoform 3 (mouse) mKCNN2/iso:3 located_in GO:0005886 plasma membrane MGI_ref:3810884|PMID:18624921 IDA NCBITaxon:10090 MGI:2153182 20121024 MGI:MGI PR:B4YDY0 small conductance calcium-activated potassium channel protein 2 isoform 3 (mouse) mKCNN2/iso:3 NOT enables GO:0005216 monoatomic ion channel activity MGI_ref:3810884|PMID:18624921 IDA NCBITaxon:10090 MGI:2153182 20121024 MGI:MGI PR:B4YDY0 small conductance calcium-activated potassium channel protein 2 isoform 3 (mouse) mKCNN2/iso:3 NOT acts_upstream_of_or_within GO:0006811 monoatomic ion transport MGI_ref:3810884|PMID:18624921 IDA NCBITaxon:10090 MGI:2153182 20121024 MGI:MGI PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse) mCRHR2/iso:iv-beta located_in GO:0005783 endoplasmic reticulum MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse) mCRHR2/iso:iv-beta located_in GO:0005794 Golgi apparatus MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse) mCRHR2/iso:iv-beta acts_upstream_of_or_within GO:0043950 positive regulation of cAMP-mediated signaling MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse) mCRHR2/iso:iv-beta acts_upstream_of_or_within GO:0043951 negative regulation of cAMP-mediated signaling MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:C0K3M3 corticotropin-releasing factor receptor 2 isoform iv-beta (mouse) mCRHR2/iso:iv-beta NOT located_in GO:0009986 cell surface MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse) mROBO3.1|mROBO3/iso:ROBO3A1|mROBO3A|mRobo3A.1 acts_upstream_of_or_within GO:0016199 axon midline choice point recognition MGI_ref:3834283|PMID:18466743 IMP NCBITaxon:10090 MGI:1343102 20140724 MGI:MGI occurs_in(EMAP:3980) PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse) mROBO3.1|mROBO3/iso:ROBO3A1|mROBO3A|mRobo3A.1 acts_upstream_of_or_within GO:0061642 chemoattraction of axon MGI_ref:3834283|PMID:18466743 IMP NCBITaxon:10090 MGI:1343102 20141016 MGI:MGI occurs_in(EMAP:3980),occurs_in(CL:0000678) PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse) mROBO3.1|mROBO3/iso:ROBO3A1|mROBO3A|mRobo3A.1 acts_upstream_of_or_within GO:0071679 commissural neuron axon guidance MGI_ref:3834283|PMID:18466743 IMP NCBITaxon:10090 MGI:1343102 20140724 MGI:MGI occurs_in(EMAP:3980) PR:E9Q9V9 retinoic acid receptor RXR-gamma isoform 2 (mouse) mRXRG/iso:2|RXR-gamma2 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:60180|PMID:8391126 IDA NCBITaxon:10090 MGI:98216 20140903 MGI:MGI has_direct_input(CHEBI:50648) PR:G1JLS7 STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse) Kidney-specific SPAK|KS-SPAK|mSTK39/iso:2 enables GO:0005515 protein binding PR:P55014-4 MGI_ref:5538439|PMID:24133122 IPI NCBITaxon:10090 MGI:1858416 20141009 MGI:MGI PR:G1JLS7 STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse) Kidney-specific SPAK|KS-SPAK|mSTK39/iso:2 acts_upstream_of_or_within GO:0001933 negative regulation of protein phosphorylation MGI_ref:5292405|PMID:21907141 IDA NCBITaxon:10090 MGI:1858416 20141015 MGI:MGI PR:G1JLS7 STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse) Kidney-specific SPAK|KS-SPAK|mSTK39/iso:2 acts_upstream_of_or_within GO:1901380 negative regulation of potassium ion transmembrane transport MGI_ref:5538439|PMID:24133122 IDA NCBITaxon:10090 MGI:1858416 20141009 MGI:MGI regulates_o_has_agent(UniProtKB:P55014) PR:G5DDB7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse) mPLCD1/iso:2|phosphoinositide phospholipase C (mouse) enables GO:0001786 phosphatidylserine binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:G5DDB7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse) mPLCD1/iso:2|phosphoinositide phospholipase C (mouse) enables GO:0004629 phospholipase C activity MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:G5DDB7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse) mPLCD1/iso:2|phosphoinositide phospholipase C (mouse) enables GO:0070300 phosphatidic acid binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:G5DDB7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse) mPLCD1/iso:2|phosphoinositide phospholipase C (mouse) enables GO:1901981 phosphatidylinositol phosphate binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:G5DDB7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 (mouse) mPLCD1/iso:2|phosphoinositide phospholipase C (mouse) located_in GO:0005737 cytoplasm MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI part_of(CL:0000182)|part_of(CL:0000155)|part_of(CL:0000162) PR:H9U1Q1 carbohydrate-responsive element-binding protein isoform 6 (mouse) carbohydrate-responsive element-binding protein isoform beta (mouse)|mMLXIPL/iso:6 located_in GO:0005634 nucleus MGI_ref:5319432|PMID:22466288 IDA NCBITaxon:10090 MGI:1927999 20150122 MGI:MGI PR:O00238-1 bone morphogenetic protein receptor type-1B isoform 1 (human) hBMPR1B/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:10051328 IDA NCBITaxon:9606 UniProtKB:O00238-1 20080301 PRO:CNA PR:O00292-1 left-right determination factor 2 isoform 1 (human) hLEFTY2/iso:1 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:10053005 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:O00292-1 left-right determination factor 2 isoform 1 (human) hLEFTY2/iso:1 acts_upstream_of_or_within GO:0007309 oocyte axis specification PMID:10053005 IDA NCBITaxon:9606 UniProtKB:O00292-1 20080301 PRO:CNA PR:O08599 syntaxin-binding protein 1 (mouse) mSTXBP1|protein unc-18 homolog 1 (mouse)|protein unc-18 homolog A (mouse)|Stxbp1|unc-18A (mouse)|Unc18-1 (mouse) acts_upstream_of_or_within GO:0007412 axon target recognition PMID:15182301 IMP NCBITaxon:10090 MGI_allele:2183278 UniProtKB:O08599 20091013 PRO:HJD PR:O08599 syntaxin-binding protein 1 (mouse) mSTXBP1|protein unc-18 homolog 1 (mouse)|protein unc-18 homolog A (mouse)|Stxbp1|unc-18A (mouse)|Unc18-1 (mouse) acts_upstream_of_or_within GO:0016188 synaptic vesicle maturation PMID:15145078 IMP NCBITaxon:10090 MGI_allele:2183278 UniProtKB:O08599 20091013 PRO:HJD PR:O08599-1 syntaxin-binding protein 1 isoform 1 (mouse) mSTXBP1/iso:1 located_in GO:0005739 mitochondrion PMID:14651853 EXP NCBITaxon:10090 UniProtKB:O08599-1 20091007 PRO:HJD PR:O08599-1 syntaxin-binding protein 1 isoform 1 (mouse) mSTXBP1/iso:1 acts_upstream_of_or_within GO:0032229 negative regulation of synaptic transmission, GABAergic PMID:17167098 EXP NCBITaxon:10090 UniProtKB:O08599-1 20091007 PRO:HJD PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 enables GO:0005515 protein binding PR:Q8R4U2 MGI_ref:3722967|PMID:17635917 IPI NCBITaxon:10090 MGI:106926 20111207 MGI:MGI PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 located_in GO:0005783 endoplasmic reticulum MGI_ref:3722967|PMID:17635917 IDA NCBITaxon:10090 MGI:106926 20091102 MGI:MGI PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 acts_upstream_of_or_within GO:0006497 protein lipidation PMID:12072432 EXP NCBITaxon:10090 UniProtKB:O08601-1 20091120 PRO:HJD PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 acts_upstream_of_or_within GO:0006629 lipid metabolic process PMID:12072432 EXP NCBITaxon:10090 UniProtKB:O08601-1 20091120 PRO:HJD PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 acts_upstream_of_or_within GO:0006641 triglyceride metabolic process PMID:12072432 EXP NCBITaxon:10090 UniProtKB:O08601-1 20091120 PRO:HJD PR:O08601-1 microsomal triglyceride transfer protein large subunit isoform 1 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-A (mouse)|mMTTP/iso:1 acts_upstream_of_or_within GO:0042953 lipoprotein transport MGI_ref:3722967|PMID:17635917 IDA NCBITaxon:10090 MGI:106926 20111207 MGI:MGI PR:O08601-2 microsomal triglyceride transfer protein large subunit isoform 2 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-B (mouse)|microsomal triglyceride transfer protein large subunit isoform MTPv1 (mouse)|mMTTP/iso:2 enables GO:0005515 protein binding PR:Q8R4U2 MGI_ref:3722967|PMID:17635917 IPI NCBITaxon:10090 MGI:106926 20140515 MGI:MGI PR:O08601-2 microsomal triglyceride transfer protein large subunit isoform 2 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-B (mouse)|microsomal triglyceride transfer protein large subunit isoform MTPv1 (mouse)|mMTTP/iso:2 located_in GO:0005794 Golgi apparatus PMID:17312007 EXP NCBITaxon:10090 UniProtKB:O08601-2 20091120 PRO:CNA PR:O08601-2 microsomal triglyceride transfer protein large subunit isoform 2 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-B (mouse)|microsomal triglyceride transfer protein large subunit isoform MTPv1 (mouse)|mMTTP/iso:2 acts_upstream_of_or_within GO:0042953 lipoprotein transport MGI_ref:3722967|PMID:17635917 IDA NCBITaxon:10090 MGI:106926 20091102 MGI:MGI PR:O08601-2 microsomal triglyceride transfer protein large subunit isoform 2 (mouse) microsomal triglyceride transfer protein large subunit isoform MTP-B (mouse)|microsomal triglyceride transfer protein large subunit isoform MTPv1 (mouse)|mMTTP/iso:2 acts_upstream_of_or_within GO:0042953 lipoprotein transport PMID:17312007 EXP NCBITaxon:10090 UniProtKB:O08601-2 20091120 PRO:CNA PR:O08710-1 thyroglobulin isoform 1 (mouse) mTG/iso:1 located_in GO:0005615 extracellular space MGI_ref:1277519|PMID:9707574 IDA NCBITaxon:10090 UniProtKB:O08710-1 20140507 PRO:HJD PR:O08901 mitotic checkpoint serine/threonine-protein kinase BUB1 (mouse) Bub1|BUB1A (mouse)|mBUB1 located_in GO:0000775 chromosome, centromeric region PMID:19965387 EXP NCBITaxon:10090 MGI:5426470|PMID:22573681 UniProtKB:O08901 20130102 PRO:KER Timing=prometaphase and metaphase of Meiosis I PR:O08901 mitotic checkpoint serine/threonine-protein kinase BUB1 (mouse) Bub1|BUB1A (mouse)|mBUB1 acts_upstream_of_or_within GO:0043069 negative regulation of programmed cell death PMID:20057499 EXP NCBITaxon:10090 MGI:1350695|PMID:10601341 UniProtKB:O08901 20130102 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 enables GO:0005515 protein binding PR:P25054 PMID:20823832 IPI NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 enables GO:0005515 protein binding PR:P33981 PMID:20823832 IPI NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 enables GO:0005515 protein binding PR:P53350 PMID:20823832 IPI NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 located_in GO:0000776 kinetochore PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 located_in GO:0000922 spindle pole PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 located_in GO:0005819 spindle PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 located_in GO:0032154 cleavage furrow PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0031589 cell-substrate adhesion PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0033674 positive regulation of kinase activity PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER Target=PR:P33981. PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER Target=PR:000035401. PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER Target=PR:O60566. PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human) dishevelled-2 (human)|DSH homolog 2 (human)|DVL2|hDVL2 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:20823832 EXP NCBITaxon:9606 UniProtKB:O14641 20121116 PRO:KER PR:O14777 kinetochore protein NDC80 (human) HEC|HEC1|highly expressed in cancer protein (human)|hNDC80|HsHec1|kinetochore protein Hec1 (human)|kinetochore-associated protein 2 (human)|KNTC2|NDC80|retinoblastoma-associated protein HEC (human) enables GO:0005515 protein binding PR:Q8NG31 BioGRID:BG-723197 IPI NCBITaxon:9606 UniProtKB:O14777 20130103 PRO:KER PR:O14777 kinetochore protein NDC80 (human) HEC|HEC1|highly expressed in cancer protein (human)|hNDC80|HsHec1|kinetochore protein Hec1 (human)|kinetochore-associated protein 2 (human)|KNTC2|NDC80|retinoblastoma-associated protein HEC (human) enables GO:0005515 protein binding PR:Q9BZD4 BioGRID:BG-252640|IntAct:EBI-999882 IPI NCBITaxon:9606 UniProtKB:O14777 20130103 PRO:KER PR:O14777 kinetochore protein NDC80 (human) HEC|HEC1|highly expressed in cancer protein (human)|hNDC80|HsHec1|kinetochore protein Hec1 (human)|kinetochore-associated protein 2 (human)|KNTC2|NDC80|retinoblastoma-associated protein HEC (human) located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:O14777 20121112 PRO:KER PR:O14777 kinetochore protein NDC80 (human) HEC|HEC1|highly expressed in cancer protein (human)|hNDC80|HsHec1|kinetochore protein Hec1 (human)|kinetochore-associated protein 2 (human)|KNTC2|NDC80|retinoblastoma-associated protein HEC (human) acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17785528 EXP NCBITaxon:9606 UniProtKB:O14777 20121112 PRO:KER Target=PR:P53350. PR:O14965 aurora kinase A (human) AIK|AIRK1|ARK-1 (human)|ARK1|AURA|AURKA|aurora 2 (human)|aurora-related kinase 1 (human)|aurora/IPL1-related kinase 1 (human)|AYK1|breast tumor-amplified kinase (human)|BTAK|hARK1|hAURKA|IAK1|serine/threonine-protein kinase 15 (human)|serine/threonine-protein kinase 6 (human)|serine/threonine-protein kinase aurora-A (human)|STK15|STK6 enables GO:0005515 protein binding PR:Q9H4B4 PMID:15190214 IPI NCBITaxon:9606 UniProtKB:O14965 20121116 PRO:KER Timing=interphase and mitosis. PR:O14965 aurora kinase A (human) AIK|AIRK1|ARK-1 (human)|ARK1|AURA|AURKA|aurora 2 (human)|aurora-related kinase 1 (human)|aurora/IPL1-related kinase 1 (human)|AYK1|breast tumor-amplified kinase (human)|BTAK|hARK1|hAURKA|IAK1|serine/threonine-protein kinase 15 (human)|serine/threonine-protein kinase 6 (human)|serine/threonine-protein kinase aurora-A (human)|STK15|STK6 located_in GO:0000922 spindle pole PMID:15190214 EXP NCBITaxon:9606 UniProtKB:O14965 20121116 PRO:KER Timing=mitosis. PR:O14965 aurora kinase A (human) AIK|AIRK1|ARK-1 (human)|ARK1|AURA|AURKA|aurora 2 (human)|aurora-related kinase 1 (human)|aurora/IPL1-related kinase 1 (human)|AYK1|breast tumor-amplified kinase (human)|BTAK|hARK1|hAURKA|IAK1|serine/threonine-protein kinase 15 (human)|serine/threonine-protein kinase 6 (human)|serine/threonine-protein kinase aurora-A (human)|STK15|STK6 located_in GO:0005813 centrosome PMID:15190214 EXP NCBITaxon:9606 UniProtKB:O14965 20121116 PRO:KER Timing=interphase. PR:O14965 aurora kinase A (human) AIK|AIRK1|ARK-1 (human)|ARK1|AURA|AURKA|aurora 2 (human)|aurora-related kinase 1 (human)|aurora/IPL1-related kinase 1 (human)|AYK1|breast tumor-amplified kinase (human)|BTAK|hARK1|hAURKA|IAK1|serine/threonine-protein kinase 15 (human)|serine/threonine-protein kinase 6 (human)|serine/threonine-protein kinase aurora-A (human)|STK15|STK6 located_in GO:0030496 midbody PMID:15190214 EXP NCBITaxon:9606 UniProtKB:O14965 20121116 PRO:KER Timing=mitosis. PR:O14980 exportin-1 (human) chromosome region maintenance 1 protein homolog (human)|CRM1|Exp1 (human)|hXPO1|XPO1 enables GO:0005515 protein binding PR:000025763 PMID:10805757 IPI NCBITaxon:9606 UniProtKB:O14980 20110513 PRO:CNA Evidence=Fig4f PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human) hSMAD7/iso:1 enables GO:0005515 protein binding PMID:9256479 IPI NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human) hSMAD7/iso:1 enables GO:0140416 transcription regulator inhibitor activity PMID:9215638 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human) hSMAD7/iso:1 located_in GO:0005634 nucleus PMID:11278814 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human) hSMAD7/iso:1 acts_upstream_of_or_within GO:0006950 response to stress PMID:9256479 TAS NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:O15105-1 mothers against decapentaplegic homolog 7 isoform 1 (human) hSMAD7/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10823886|PMID:9215638 IDA NCBITaxon:9606 UniProtKB:O15105-1 20080301 PRO:CNA PR:O15169-1 Axin-1 isoform 1 (human) hAXIN1/iso:1 enables GO:0005515 protein binding PR:000036448 PMID:19131971 IPI NCBITaxon:9606 UniProtKB:O15169-1 20101020 PRO:CNA PR:O15169-1 Axin-1 isoform 1 (human) hAXIN1/iso:1 enables GO:0060090 molecular adaptor activity PMID:19131971 EXP NCBITaxon:9606 UniProtKB:O15169-1 20101020 PRO:CNA PR:O15392 baculoviral IAP repeat-containing protein 5 (human) API4|apoptosis inhibitor 4 (human)|apoptosis inhibitor survivin (human)|BIRC5|hBIRC5|IAP4|survivin (human) located_in GO:0000779 condensed chromosome, centromeric region PMID:12719470|PMID:15917996 EXP NCBITaxon:9606 UniProtKB:O15392 20121023 PRO:KER Timing=prometaphase, metaphase. PR:O15392 baculoviral IAP repeat-containing protein 5 (human) API4|apoptosis inhibitor 4 (human)|apoptosis inhibitor survivin (human)|BIRC5|hBIRC5|IAP4|survivin (human) located_in GO:0030496 midbody PMID:15917996 EXP NCBITaxon:9606 UniProtKB:O15392 20121023 PRO:KER Timing=telophase. PR:O15392 baculoviral IAP repeat-containing protein 5 (human) API4|apoptosis inhibitor 4 (human)|apoptosis inhibitor survivin (human)|BIRC5|hBIRC5|IAP4|survivin (human) located_in GO:0051233 spindle midzone PMID:15917996 EXP NCBITaxon:9606 UniProtKB:O15392 20121023 PRO:KER Timing=anaphase. PR:O15392 baculoviral IAP repeat-containing protein 5 (human) API4|apoptosis inhibitor 4 (human)|apoptosis inhibitor survivin (human)|BIRC5|hBIRC5|IAP4|survivin (human) acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:20929775 EXP NCBITaxon:9606 UniProtKB:O15392 20121023 PRO:KER Target=PR:Q96GD4. Target=PR:Q9NQS7. Target=PR:Q53HL2. PR:O15554 intermediate conductance calcium-activated potassium channel protein 4 (human) hIKCa1|hKCNN4|IK1|IKCA1|KCa3.1 (human)|KCA4|KCNN4|putative Gardos channel (human)|SK4|SKCa 4 (human)|SKCa4 (human) enables GO:0005516 calmodulin binding PMID:10026195 IDA NCBITaxon:9606 UniProtKB:O15554 20080601 PRO:CNA PR:O15554 intermediate conductance calcium-activated potassium channel protein 4 (human) hIKCa1|hKCNN4|IK1|IKCA1|KCa3.1 (human)|KCA4|KCNN4|putative Gardos channel (human)|SK4|SKCa 4 (human)|SKCa4 (human) acts_upstream_of_or_within GO:0006952 defense response PMID:11278890|PMID:9407042 IDA NCBITaxon:9606 UniProtKB:O15554 20080915 PRO:CNA PR:O15554-1 intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (human) hKCNN4/iso:1 enables GO:0005516 calmodulin binding PMID:10026195 IDA NCBITaxon:9606 UniProtKB:O15554-1 20080915 PRO:CNA PR:O15554-1 intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (human) hKCNN4/iso:1 located_in GO:0009986 cell surface PMID:11395478 IDA NCBITaxon:9606 UniProtKB:O15554-1 20080915 PRO:CNA PR:O22476 protein BRASSINOSTEROID INSENSITIVE 1 (Arabidopsis thaliana) At-BRI1|At4g39400|AtBRI1|brassinosteroid LRR receptor kinase (Arabidopsis thaliana)|BRI1|F23K16.30 enables GO:0004713 protein tyrosine kinase activity PMID:21350342 EXP NCBITaxon:3702 UniProtKB:O22476 20130430 PRO:LVM Target=PR:Q94F62-1. PR:O22476 protein BRASSINOSTEROID INSENSITIVE 1 (Arabidopsis thaliana) At-BRI1|At4g39400|AtBRI1|brassinosteroid LRR receptor kinase (Arabidopsis thaliana)|BRI1|F23K16.30 enables GO:0005516 calmodulin binding PMID:22309147 EXP NCBITaxon:3702 UniProtKB:O22476 20130429 PRO:LVM PR:O22476 protein BRASSINOSTEROID INSENSITIVE 1 (Arabidopsis thaliana) At-BRI1|At4g39400|AtBRI1|brassinosteroid LRR receptor kinase (Arabidopsis thaliana)|BRI1|F23K16.30 acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:21350342 EXP NCBITaxon:3702 UniProtKB:O22476 20130430 PRO:LVM PR:O22932 CBL-interacting serine/threonine-protein kinase 11 (Arabidopsis thaliana) At-CIPK11|At2g30360|CIPK11|PKS5|SIP4|SNF1-related kinase 3.22 (Arabidopsis thaliana)|SnRK3.22|SOS2-like protein kinase PKS5 (Arabidopsis thaliana)|SOS3-interacting protein 4 (Arabidopsis thaliana)|T9D9.17 enables GO:0004672 protein kinase activity PMID:21685179 EXP NCBITaxon:3702 UniProtKB:O22932 20140415 PRO:CNA Target=PR:Q8LAS7. Evidence=ECO:0000178. PR:O24606 protein ETHYLENE INSENSITIVE 3 (Arabidopsis thaliana) At-EIN3|At3g20770|EIN3|MOE17.8 enables GO:0003700 DNA-binding transcription factor activity PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606 20140415 PRO:LVM PR:O24606 protein ETHYLENE INSENSITIVE 3 (Arabidopsis thaliana) At-EIN3|At3g20770|EIN3|MOE17.8 located_in GO:0005634 nucleus PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606 20140415 PRO:LVM PR:O24606 protein ETHYLENE INSENSITIVE 3 (Arabidopsis thaliana) At-EIN3|At3g20770|EIN3|MOE17.8 acts_upstream_of_or_within GO:0010104 regulation of ethylene-activated signaling pathway PMID:18273012 EXP NCBITaxon:3702 UniProtKB:O24606 20140415 PRO:LVM PR:O35147-1 Bcl2-associated agonist of cell death isoform Alpha (rat) rBAD/iso:Alpha enables GO:0005515 protein binding PR:O88996-1 PMID:11161472 IPI NCBITaxon:10116 UniProtKB:O35147-1 20090918 PRO:JAN PR:O35147-1 Bcl2-associated agonist of cell death isoform Alpha (rat) rBAD/iso:Alpha acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process PMID:11161472 EXP NCBITaxon:10116 UniProtKB:O35147-1 20090918 PRO:JAN PR:O35147-2 Bcl2-associated agonist of cell death isoform Beta (rat) rBAD/iso:Beta enables GO:0005515 protein binding PR:O88996-1 PMID:11161472 IPI NCBITaxon:10116 UniProtKB:O35147-2 20090918 PRO:JAN PR:O35147-2 Bcl2-associated agonist of cell death isoform Beta (rat) rBAD/iso:Beta acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process PMID:11161472 EXP NCBITaxon:10116 UniProtKB:O35147-2 20090918 PRO:JAN PR:O35173-1 potassium voltage-gated channel subfamily S member 1 isoform 1 (mouse) mKCNS1/iso:1 enables GO:0015459 potassium channel regulator activity PMID:9305895 IDA NCBITaxon:10090 UniProtKB:O35173-1 20080601 PRO:CNA PR:O35174-1 potassium voltage-gated channel subfamily S member 2 isoform 1 (mouse) mKCNS2/iso:1 enables GO:0015459 potassium channel regulator activity PMID:9305895 IDA NCBITaxon:10090 UniProtKB:O35174-1 20080601 PRO:CNA PR:O35182-1 mothers against decapentaplegic homolog 6 isoform 1 (mouse) mSMAD6/iso:1 enables GO:0140416 transcription regulator inhibitor activity PMID:17118358 IDA NCBITaxon:10090 UniProtKB:O35182-1 20080301 PRO:CNA PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) located_in GO:0005635 nuclear envelope MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 MGI:1341722 20080811 MGI:MGI part_of(EMAP:2)|part_of(EMAP:6) PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) located_in GO:0005635 nuclear envelope MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 UniProtKB:O35219-1 20080601 PRO:CNA Timing=in G2 phase PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) located_in GO:0005737 cytoplasm MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 MGI:1341722 20100416 MGI:MGI part_of(EMAP:6)|part_of(EMAP:2) PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) located_in GO:0005737 cytoplasm MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 UniProtKB:O35219-1 20080601 PRO:CNA Timing=unfertilized oocytes and right after fertilization PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) located_in GO:0005886 plasma membrane MGI_ref:3040012|PMID:14668215 IDA NCBITaxon:10090 MGI:1341722 20080811 MGI:MGI part_of(EMAP:8)|part_of(EMAP:6) PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) part_of GO:0008076 voltage-gated potassium channel complex PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-1 20151104 PRO:CNA PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse) mKCNH2/iso:A|potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse) contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9351446|PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-1 20080601 PRO:CNA PR:O35219-2 potassium voltage-gated channel subfamily H member 2 isoform 1A' (mouse) Kcnh2 isoform 2 (mouse)|mKCNH2/iso:1A'|potassium voltage-gated channel subfamily H member 2 isoform 2 (mouse) enables GO:0005251 delayed rectifier potassium channel activity PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-2 20080601 PRO:CNA PR:O35219-2 potassium voltage-gated channel subfamily H member 2 isoform 1A' (mouse) Kcnh2 isoform 2 (mouse)|mKCNH2/iso:1A'|potassium voltage-gated channel subfamily H member 2 isoform 2 (mouse) part_of GO:0008076 voltage-gated potassium channel complex PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-2 20080601 PRO:CNA PR:O35219-3 potassium voltage-gated channel subfamily H member 2 isoform B (mouse) Kcnh2 isoform 3 (mouse)|mKCNH2/iso:B|potassium voltage-gated channel subfamily H member 2 isoform 1B (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 3 (mouse) part_of GO:0008076 voltage-gated potassium channel complex PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-3 20080601 PRO:CNA PR:O35219-3 potassium voltage-gated channel subfamily H member 2 isoform B (mouse) Kcnh2 isoform 3 (mouse)|mKCNH2/iso:B|potassium voltage-gated channel subfamily H member 2 isoform 1B (mouse)|potassium voltage-gated channel subfamily H member 2 isoform 3 (mouse) contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9351446|PMID:9351462 IDA NCBITaxon:10090 UniProtKB:O35219-3 20080601 PRO:CNA PR:O35317-1 pre-B-cell leukemia transcription factor 3 isoform 1 (mouse) mPBX3/iso:1|PBX3a (mouse) enables GO:0005515 protein binding PR:O55144|PR:Q60954-1 MGI_ref:3505657|PMID:15466398 IPI NCBITaxon:10090 MGI:97496 20080829 MGI:MGI PR:O35426-2 X-box-binding protein 1 isoform 2 (mouse) mXBP1/iso:2|XBP-1S (mouse) enables GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding PR:Q9R1E0 MGI_ref:4946566|PMID:21317886 IPI NCBITaxon:10090 MGI:98970 20131105 MGI:MGI PR:O35426-2 X-box-binding protein 1 isoform 2 (mouse) mXBP1/iso:2|XBP-1S (mouse) acts_upstream_of_or_within GO:0042593 glucose homeostasis MGI_ref:4946566|PMID:21317886 IDA NCBITaxon:10090 MGI:98970 20131105 MGI:MGI PR:O35426-2 X-box-binding protein 1 isoform 2 (mouse) mXBP1/iso:2|XBP-1S (mouse) acts_upstream_of_or_within GO:1901800 positive regulation of proteasomal protein catabolic process MGI_ref:4946566|PMID:21317886 IDA NCBITaxon:10090 MGI:98970 20131105 MGI:MGI PR:O35607-1 bone morphogenetic protein receptor type-2 isoform 1 (mouse) mBMPR2/iso:1 located_in GO:0009986 cell surface PMID:12117821 IDA NCBITaxon:10090 UniProtKB:O35607-1 20080301 PRO:CNA PR:O35607-1 bone morphogenetic protein receptor type-2 isoform 1 (mouse) mBMPR2/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:12117821 IDA NCBITaxon:10090 UniProtKB:O35607-1 20080301 PRO:CNA PR:O35615-1 zinc finger protein ZFPM1 isoform 1 (mouse) FOG1L (mouse)|mZFPM1/iso:1 located_in GO:0005634 nucleus MGI_ref:4422158|PMID:19654328 IDA NCBITaxon:10090 MGI:1095400 20111216 MGI:MGI PR:O35615-1 zinc finger protein ZFPM1 isoform 1 (mouse) FOG1L (mouse)|mZFPM1/iso:1 located_in GO:0005737 cytoplasm MGI_ref:4422158|PMID:19654328 IDA NCBITaxon:10090 MGI:1095400 20111216 MGI:MGI PR:O35625-1 Axin-1 isoform 1 (mouse) mAXIN1/iso:1 enables GO:0008013 beta-catenin binding MGI_ref:4462715|PMID:10581160 IMP NCBITaxon:10090 MGI:1096327 20101007 MGI:MGI PR:O35625-1 Axin-1 isoform 1 (mouse) mAXIN1/iso:1 acts_upstream_of_or_within GO:0030178 negative regulation of Wnt signaling pathway MGI_ref:4462715|PMID:10581160 IDA NCBITaxon:10090 MGI:1096327 20101007 MGI:MGI PR:O35704 serine palmitoyltransferase 1 (mouse) LCB 1 (mouse)|Lcb1|long chain base biosynthesis protein 1 (mouse)|mSPTLC1|serine-palmitoyl-CoA transferase 1 (mouse)|SPT 1 (mouse)|SPT1 (mouse)|Sptlc1 acts_upstream_of_or_within GO:0006686 sphingomyelin biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815115 UniProtKB:O35704 20100215 PRO:HJD PR:O35704 serine palmitoyltransferase 1 (mouse) LCB 1 (mouse)|Lcb1|long chain base biosynthesis protein 1 (mouse)|mSPTLC1|serine-palmitoyl-CoA transferase 1 (mouse)|SPT 1 (mouse)|SPT1 (mouse)|Sptlc1 acts_upstream_of_or_within GO:0046511 sphinganine biosynthetic process PMID:19416652 IMP NCBITaxon:10090 MGI_allele:3815115 UniProtKB:O35704 20100215 PRO:HJD PR:O35704 serine palmitoyltransferase 1 (mouse) LCB 1 (mouse)|Lcb1|long chain base biosynthesis protein 1 (mouse)|mSPTLC1|serine-palmitoyl-CoA transferase 1 (mouse)|SPT 1 (mouse)|SPT1 (mouse)|Sptlc1 acts_upstream_of_or_within GO:0046512 sphingosine biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815115 UniProtKB:O35704 20100215 PRO:HJD PR:O35704 serine palmitoyltransferase 1 (mouse) LCB 1 (mouse)|Lcb1|long chain base biosynthesis protein 1 (mouse)|mSPTLC1|serine-palmitoyl-CoA transferase 1 (mouse)|SPT 1 (mouse)|SPT1 (mouse)|Sptlc1 acts_upstream_of_or_within GO:0046513 ceramide biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815115 UniProtKB:O35704 20100215 PRO:HJD PR:O35704-1 serine palmitoyltransferase 1 isoform 1 (mouse) mSPTLC1/iso:1 enables GO:0005515 protein binding PR:P41233 PMID:18484747 IPI NCBITaxon:10090 UniProtKB:O35704-1 20100215 PRO:HJD PR:O35704-1 serine palmitoyltransferase 1 isoform 1 (mouse) mSPTLC1/iso:1 NOT enables GO:0004758 serine C-palmitoyltransferase activity PMID:9363775 IDA NCBITaxon:10090 UniProtKB:O35704-1 20100215 PRO:HJD PR:O35716 suppressor of cytokine signaling 1 (mouse) Cish1|JAB (mouse)|JAK-binding protein (mouse)|mSOCS1|SOCS-1 (mouse)|Socs1|SSI-1 (mouse)|Ssi1|STAT-induced STAT inhibitor 1 (mouse) enables GO:0005515 protein binding PR:Q9JHF9 PMID:19296467 IPI NCBITaxon:10090 UniProtKB:O35716 20140514 PRO:CNA PR:O35716 suppressor of cytokine signaling 1 (mouse) Cish1|JAB (mouse)|JAK-binding protein (mouse)|mSOCS1|SOCS-1 (mouse)|Socs1|SSI-1 (mouse)|Ssi1|STAT-induced STAT inhibitor 1 (mouse) acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:19296467 EXP NCBITaxon:10090 UniProtKB:O35716 20140514 PRO:CNA PR:O35716 suppressor of cytokine signaling 1 (mouse) Cish1|JAB (mouse)|JAK-binding protein (mouse)|mSOCS1|SOCS-1 (mouse)|Socs1|SSI-1 (mouse)|Ssi1|STAT-induced STAT inhibitor 1 (mouse) acts_upstream_of_or_within GO:0034144 negative regulation of toll-like receptor 4 signaling pathway PMID:19296467 EXP NCBITaxon:10090 UniProtKB:O35716 20140514 PRO:CNA PR:O43264 centromere/kinetochore protein zw10 homolog (human) hZW10|ZW10 located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:O43264 20130102 PRO:KER PR:O43521-2 Bcl-2-like protein 11 isoform BimL (human) Bcl-2-like protein 11 isoform Bim(L) (human)|hBCL2L11/iso:BimL enables GO:0005515 protein binding PR:Q07812 PMID:14764673 IPI NCBITaxon:9606 UniProtKB:O43521-2 20090918 PRO:JAN PR:O43525 potassium voltage-gated channel subfamily KQT member 3 (human) hKCNQ3|KCNQ3|KQT-like 3 (human)|potassium channel subunit alpha KvLQT3 (human)|voltage-gated potassium channel subunit Kv7.3 (human) acts_upstream_of_or_within GO:0006813 potassium ion transport PMID:9677360 IDA NCBITaxon:9606 UniProtKB:O43525 20080601 PRO:CNA PR:O43525 potassium voltage-gated channel subfamily KQT member 3 (human) hKCNQ3|KCNQ3|KQT-like 3 (human)|potassium channel subunit alpha KvLQT3 (human)|voltage-gated potassium channel subunit Kv7.3 (human) acts_upstream_of_or_within GO:0007268 chemical synaptic transmission PMID:9425900 IDA NCBITaxon:9606 UniProtKB:O43525 20080601 PRO:CNA PR:O43526-2 potassium voltage-gated channel subfamily KQT member 2 isoform 2 (human) hKCNQ2/iso:2 contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:11160379 IDA NCBITaxon:9606 UniProtKB:O43526-2 20080601 PRO:CNA PR:O43526-4 potassium voltage-gated channel subfamily KQT member 2 isoform 4 (human) hKCNQ2/iso:4 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9836639 IDA NCBITaxon:9606 UniProtKB:O43526-4 20080601 PRO:CNA PR:O43526-6 potassium voltage-gated channel subfamily KQT member 2 isoform 6 (human) hKCNQ2/iso:6|potassium voltage-gated channel subfamily KQT member 2 isoform HNSPC (human) decreased|contributes_to enables GO:0005249 voltage-gated potassium channel activity PR:000002632 PMID:9039501 IDA NCBITaxon:9606 UniProtKB:O43526-6 20080601 PRO:CNA PR:O43541-1 mothers against decapentaplegic homolog 6 isoform A (human) hSMAD6/iso:A enables GO:0005515 protein binding PR:000026334 PMID:9436979 IPI NCBITaxon:9606 UniProtKB:O43541-1 20080301 PRO:CNA PR:O43541-1 mothers against decapentaplegic homolog 6 isoform A (human) hSMAD6/iso:A enables GO:0140416 transcription regulator inhibitor activity PMID:9436979 IDA NCBITaxon:9606 UniProtKB:O43541-1 20080301 PRO:CNA PR:O43541-2 mothers against decapentaplegic homolog 6 isoform B (human) hSMAD6/iso:B|mothers against decapentaplegic homolog 6 isoform Smad 6S (human) enables GO:0140416 transcription regulator inhibitor activity PMID:11284962 IDA NCBITaxon:9606 UniProtKB:O43541-2 20080301 PRO:CNA PR:O43541-2 mothers against decapentaplegic homolog 6 isoform B (human) hSMAD6/iso:B|mothers against decapentaplegic homolog 6 isoform Smad 6S (human) enables GO:0005515 protein binding PMID:11284962 IPI NCBITaxon:9606 UniProtKB:O43541-2 20080301 PRO:CNA PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0004672 protein kinase activity PMID:10198256 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:O43684 PMID:10198256|PMID:15525512 IPI NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Note=Interaction observed through out the cell cycle. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:O60566 PMID:11792804 IPI NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Note=Interaction observed in nocodazole. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:P04637-1 PMID:19252416 IPI NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:P25054 BioGRID:BG-302960 IPI NCBITaxon:9606 UniProtKB:O43683 20130103 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:P53350 BioGRID:BG-718371 IPI NCBITaxon:9606 UniProtKB:O43683 20130103 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:Q8NG31 BioGRID:BG-723200 IPI NCBITaxon:9606 UniProtKB:O43683 20130103 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 enables GO:0005515 protein binding PR:Q9Y6D9 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Timing=Mitosis (prophase, prometaphase, metaphase) and spindle disruption (nocodazole). Localization is increased by PR:Q9NQS7. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 located_in GO:0000939 inner kinetochore PMID:11792804 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 located_in GO:0000940 outer kinetochore PMID:11792804|PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0007059 chromosome segregation PMID:16580887 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0007062 sister chromatid cohesion PMID:16580887 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:19252416 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0043069 negative regulation of programmed cell death PMID:20057499 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:16580887 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=PR:P30153. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=PR:Q5FBB7. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:21658950 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=phospho-Thr-3-Histone H3. PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) BUB1|BUB1A (human)|BUB1L|hBUB1 acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:21658950 EXP NCBITaxon:9606 UniProtKB:O43683 20121105 PRO:KER Target=PR:Q96GD4. PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O15350-1 PMID:20057499 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O15350-2 PMID:20057499 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O15350-3 PMID:20057499 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O15350-5 PMID:20057499 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O43683 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:O60566 PMID:17785528 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:P25054 BioGRID:BG-302961 IPI NCBITaxon:9606 UniProtKB:O43684 20130103 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:Q12834 BioGRID:BG-561804|MINT:MINT-8183848 IPI NCBITaxon:9606 UniProtKB:O43684 20130103 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:Q13257 BioGRID:BG-718926 IPI NCBITaxon:9606 UniProtKB:O43684 20130103 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 enables GO:0005515 protein binding PR:Q9Y6D9 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER PR:O43684 mitotic checkpoint protein BUB3 (human) BUB3|hBUB3 located_in GO:0000776 kinetochore PMID:11283619 EXP NCBITaxon:9606 UniProtKB:O43684 20121112 PRO:KER Timing=Mitosis (prophase, pro-metaphase, metaphase). PR:O48814-1 serine/threonine-protein kinase BIK1 isoform 1 (Arabidopsis thaliana) At-BIK1/iso:1 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:20018686 EXP NCBITaxon:3702 UniProtKB:O48814-1 20130424 PRO:LVM PR:O54709-1 NKG2-D type II integral membrane protein isoform 1 (mouse) mKLRK1/iso:1|NKG2-D type II integral membrane protein isoform NKG2D long (mouse)|NKG2-D type II integral membrane protein isoform NKG2D-L (mouse) enables GO:0005515 protein binding PR:Q9QUJ0 MGI_ref:5629693|PMID:12426565 IPI NCBITaxon:10090 MGI:1196250 20150415 MGI:MGI PR:O54709-1 NKG2-D type II integral membrane protein isoform 1 (mouse) mKLRK1/iso:1|NKG2-D type II integral membrane protein isoform NKG2D long (mouse)|NKG2-D type II integral membrane protein isoform NKG2D-L (mouse) located_in GO:0009986 cell surface MGI_ref:5629693|PMID:12426565 IDA NCBITaxon:10090 MGI:1196250 20150415 MGI:MGI PR:O54709-2 NKG2-D type II integral membrane protein isoform 2 (mouse) mKLRK1/iso:2|NKG2-D type II integral membrane protein isoform NKG2D short (mouse)|NKG2-D type II integral membrane protein isoform NKG2D-S (mouse) enables GO:0005515 protein binding PR:O54885|PR:Q9QUJ0 MGI_ref:5629693|PMID:12426565 IPI NCBITaxon:10090 MGI:1196250 20150415 MGI:MGI PR:O54709-2 NKG2-D type II integral membrane protein isoform 2 (mouse) mKLRK1/iso:2|NKG2-D type II integral membrane protein isoform NKG2D short (mouse)|NKG2-D type II integral membrane protein isoform NKG2D-S (mouse) located_in GO:0009986 cell surface MGI_ref:5629693|PMID:12426565 IDA NCBITaxon:10090 MGI:1196250 20150415 MGI:MGI PR:O54828-2 regulator of G-protein signaling 9 isoform 1 (mouse) mRGS9/iso:1|regulator of G-protein signaling 9 isoform RGS9-1 (mouse) located_in GO:0001750 photoreceptor outer segment MGI_ref:5507748|PMID:23555598 IDA NCBITaxon:10090 MGI:1338824 20150108 MGI:MGI part_of(CL:0000604),happens_during(GO:0036367) PR:O54828-2 regulator of G-protein signaling 9 isoform 1 (mouse) mRGS9/iso:1|regulator of G-protein signaling 9 isoform RGS9-1 (mouse) located_in GO:0001917 photoreceptor inner segment MGI_ref:5507748|PMID:23555598 IDA NCBITaxon:10090 MGI:1338824 20150108 MGI:MGI part_of(CL:0000604),happens_during(GO:1990603) PR:O54990-3 prominin-1 isoform 3 (mouse) mPROM1/iso:3|prominin-1 isoform S3 (mouse) located_in GO:0009986 cell surface PMID:15316084 IDA NCBITaxon:10090 UniProtKB:O54990-3 20090209 PRO:HJD PR:O54990-3 prominin-1 isoform 3 (mouse) mPROM1/iso:3|prominin-1 isoform S3 (mouse) located_in GO:0042995 cell projection PMID:15316084 IDA NCBITaxon:10090 UniProtKB:O54990-3 20090209 PRO:HJD PR:O54990-6 prominin-1 isoform 6 (mouse) mPROM1/iso:6|prominin-1 isoform S6 (mouse) located_in GO:0009986 cell surface PMID:15316084 IDA NCBITaxon:10090 UniProtKB:O54990-6 20090209 PRO:HJD PR:O54990-6 prominin-1 isoform 6 (mouse) mPROM1/iso:6|prominin-1 isoform S6 (mouse) located_in GO:0042995 cell projection PMID:15316084 IDA NCBITaxon:10090 UniProtKB:O54990-6 20090209 PRO:HJD PR:O55095 vascular endothelial growth factor receptor 1 isoform 2 (mouse) mFLT1/iso:2 acts_upstream_of_or_within GO:0002040 sprouting angiogenesis PMID:19758562 EXP NCBITaxon:10090 UniProtKB:O55095 20100505 PRO:HJD PR:O55230-1 DNA repair protein RAD51 homolog 4 isoform 1 (mouse) mRad51d/iso:1 enables GO:0005515 protein binding PR:Q924H5-1 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:O55230-1 DNA repair protein RAD51 homolog 4 isoform 1 (mouse) mRad51d/iso:1 enables GO:0005515 protein binding PR:Q9CX47 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:O55230-1 DNA repair protein RAD51 homolog 4 isoform 1 (mouse) mRad51d/iso:1 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:O55230-1 DNA repair protein RAD51 homolog 4 isoform 1 (mouse) mRad51d/iso:1 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:O55230-1 DNA repair protein RAD51 homolog 4 isoform 1 (mouse) mRad51d/iso:1 acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:O59767 mitotic spindle checkpoint component mad3 (Schizosaccharomyces pombe 972h-) mad3|SPCC1795.01c|SPCC895.02|Spom972h-MAD3 enables GO:0005515 protein binding PR:O14417 PMID:12676091 IPI NCBITaxon:284812 UniProtKB:O59767 20130102 PRO:KER Timing=spindle disruption. PR:O59767 mitotic spindle checkpoint component mad3 (Schizosaccharomyces pombe 972h-) mad3|SPCC1795.01c|SPCC895.02|Spom972h-MAD3 located_in GO:0000776 kinetochore PMID:12676091 EXP NCBITaxon:284812 UniProtKB:O59767 20130102 PRO:KER Timing=spindle disruption. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:000035449 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:000035450 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O15350 BioGRID:BG-717441 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O15379 MINT:MINT-7302235 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O43683 PMID:11792804 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O43684 PMID:20016069 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Note=Interaction occurs under nocodazole treatment. Kinetochore localization increased in this condition. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O76070 BioGRID:BG-253351 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:O95997 BioGRID:BG-721860 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P04049 PMID:20703093 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P04637-1 PMID:17671183 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=spindle depolymerization (nocodazole). PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P09874 BioGRID:BG-480411 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P25054 BioGRID:BG-302963 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P51587 PMID:10749118 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:P63010 BioGRID:BG-283405 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q02224 PMID:17785528 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q12834 PMID:11030144|PMID:20624902 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q13042 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q13257 PMID:20624902 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=interphase and mitosis. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q13547 MINT:MINT-7302173 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q15013 BioGRID:BG-719779 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q8NG31 BioGRID:BG-697203 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q92769 MINT:MINT-7302197 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q92831 MINT:MINT-7299740 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q96GD4 BioGRID:BG-717911 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q96IF1 BioGRID:BG-717913 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q9H081 BioGRID:BG-715437 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q9H4B4 PMID:15190214 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q9NQS7 PMID:16760428|PMID:17785528 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q9UJX3 BioGRID:BG-316229 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0005515 protein binding PR:Q9UJX5 BioGRID:BG-682429 IPI NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0016301 kinase activity PMID:11030144 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0055105 ubiquitin-protein transferase inhibitor activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:000035369 PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 enables GO:0055105 ubiquitin-protein transferase inhibitor activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:000035371 PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 located_in GO:0000776 kinetochore PMID:12719470|PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=Mitosis (prophase, prometaphase, metaphase). Kinetochore localization increased by O43683 (Bub1). PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 located_in GO:0000922 spindle pole PMID:15190214 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=metaphase. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 located_in GO:0000939 inner kinetochore PMID:11792804 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 located_in GO:0000940 outer kinetochore PMID:11792804 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 located_in GO:0005737 cytoplasm PMID:10749118 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Timing=interphase. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0006469 negative regulation of protein kinase activity PMID:15592459 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:000035365. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:11030144 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0031647 regulation of protein stability PMID:17671183 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:P04637-1. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:12719470|PMID:15592459 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0051444 negative regulation of ubiquitin-protein transferase activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:000035369. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0051444 negative regulation of ubiquitin-protein transferase activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:000035371. PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 acts_upstream_of_or_within GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore PMID:15592459 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) BUB1B|BUBR1|hBUB1B|hBUBR1|MAD3/BUB1-related protein kinase (human)|MAD3L|mitotic checkpoint kinase MAD3L (human)|protein SSK1 (human)|SSK1 NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:O60566 20121105 PRO:KER Target=PR:Q9NQS7. Timing=Mitosis. PR:O60858-1 E3 ubiquitin-protein ligase TRIM13 isoform 1 (human) hTRIM13/iso:1 located_in GO:0005737 cytoplasm PMID:11331580 IDA NCBITaxon:9606 UniProtKB:O60858-1 20110116 GOA:UniProtKB PR:O70161-1 phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 1 (mouse) mPIP5K1C/iso:1|p90 (mouse)|PIPKIgamma661 (mouse) enables GO:1990147 talin binding MGI_ref:5488558|PMID:23372168 IDA NCBITaxon:10090 MGI:1298224 20130730 MGI:MGI occurs_in(CL:0000556) PR:O70161-3 phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 2 (mouse) mPIP5K1C/iso:2|p87 (mouse)|PIPKIgamma635 (mouse) NOT enables GO:1990147 talin binding MGI_ref:5488558|PMID:23372168 IDA NCBITaxon:10090 MGI:1298224 20130730 MGI:MGI occurs_in(CL:0000556) PR:O70165-1 ficolin-1 isoform 1 (mouse) mFCN1/iso:1 enables GO:0005515 protein binding PR:Q91WP0-1|PR:Q91WP0-2 MGI_ref:5473786|PMID:16328467 IPI NCBITaxon:10090 MGI:1340905 20140401 MGI:MGI PR:O70165-1 ficolin-1 isoform 1 (mouse) mFCN1/iso:1 enables GO:0097367 carbohydrate derivative binding MGI_ref:5473786|PMID:16328467 IDA NCBITaxon:10090 MGI:1340905 20131022 MGI:MGI PR:O70165-1 ficolin-1 isoform 1 (mouse) mFCN1/iso:1 acts_upstream_of_or_within GO:0001867 complement activation, lectin pathway MGI_ref:5473786|PMID:16328467 IDA NCBITaxon:10090 MGI:1340905 20131022 MGI:MGI PR:O75116-1 Rho-associated protein kinase 2 isoform 1 (human) hROCK2/iso:1 enables GO:0004674 protein serine/threonine kinase activity PMID:9933571 TAS NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:O75116-1 Rho-associated protein kinase 2 isoform 1 (human) hROCK2/iso:1 enables GO:0031267 small GTPase binding PMID:11350930 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:O75116-1 Rho-associated protein kinase 2 isoform 1 (human) hROCK2/iso:1 located_in GO:0005622 intracellular anatomical structure PMID:16574662 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:O75116-1 Rho-associated protein kinase 2 isoform 1 (human) hROCK2/iso:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:9933571 TAS NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:O75116-1 Rho-associated protein kinase 2 isoform 1 (human) hROCK2/iso:1 acts_upstream_of_or_within GO:0051260 protein homooligomerization PMID:15291762 IDA NCBITaxon:9606 UniProtKB:O75116-1 20080301 PRO:CNA PR:O88509-1 DNA (cytosine-5)-methyltransferase 3B isoform 1 (mouse) DNA (cytosine-5)-methyltransferase 3B isoform 5 (mouse)|DNMT3B5 (mouse)|mDNMT3B/iso:1 located_in GO:0005634 nucleus MGI_ref:4367296|PMID:19796622 IDA NCBITaxon:10090 MGI:1261819 20110912 MGI:MGI PR:O88587-1 catechol O-methyltransferase isoform 1 (mouse) MB-COMT (mouse)|mCOMT/iso:1|membrane bound COMT acts_upstream_of_or_within GO:0042417 dopamine metabolic process MGI_ref:4830461|PMID:19930170 IMP NCBITaxon:10090 MGI_allele:2178542|MGI_allele:4830700 MGI:88470 20100930 MGI:MGI PR:O88587-1 catechol O-methyltransferase isoform 1 (mouse) MB-COMT (mouse)|mCOMT/iso:1|membrane bound COMT NOT located_in GO:0005886 plasma membrane MGI_ref:4822307|PMID:20374420 IDA NCBITaxon:10090 MGI:88470 20100930 MGI:MGI part_of(MA:0000168) PR:O88587-2 catechol O-methyltransferase isoform 2 (mouse) mCOMT/iso:2|s-COMT (mouse)|soluble COMT (mouse) enables GO:0016206 catechol O-methyltransferase activity MGI_ref:4830461|PMID:19930170 IMP NCBITaxon:10090 MGI_allele:4830700 MGI:88470 20100930 MGI:MGI occurs_in(MA:0000358)|occurs_in(MA:0000338)|occurs_in(MA:0000891)|occurs_in(MA:0000185) PR:O88587-2 catechol O-methyltransferase isoform 2 (mouse) mCOMT/iso:2|s-COMT (mouse)|soluble COMT (mouse) acts_upstream_of_or_within GO:0009712 catechol-containing compound metabolic process MGI_ref:4830461|PMID:19930170 IMP NCBITaxon:10090 MGI_allele:4830700 MGI:88470 20100930 MGI:MGI occurs_in(MA:0000358)|occurs_in(MA:0000338)|occurs_in(MA:0000891)|occurs_in(MA:0000185) PR:O88587-2 catechol O-methyltransferase isoform 2 (mouse) mCOMT/iso:2|s-COMT (mouse)|soluble COMT (mouse) acts_upstream_of_or_within GO:0042417 dopamine metabolic process MGI_ref:4830461|PMID:19930170 IMP NCBITaxon:10090 MGI_allele:2178542|MGI_allele:4830700 MGI:88470 20111216 MGI:MGI PR:O88623-1 ubiquitin carboxyl-terminal hydrolase 2 isoform 1 (mouse) mUSP2/iso:1|Usp2-69 (mouse) located_in GO:0005634 nucleus MGI_ref:5528783|PMID:24005904 IDA NCBITaxon:10090 MGI:1858178 20140717 MGI:MGI PR:O88623-1 ubiquitin carboxyl-terminal hydrolase 2 isoform 1 (mouse) mUSP2/iso:1|Usp2-69 (mouse) located_in GO:0005737 cytoplasm MGI_ref:5528783|PMID:24005904 IDA NCBITaxon:10090 MGI:1858178 20140717 MGI:MGI PR:O88623-1 ubiquitin carboxyl-terminal hydrolase 2 isoform 1 (mouse) mUSP2/iso:1|Usp2-69 (mouse) located_in GO:0005938 cell cortex MGI_ref:3624565|PMID:14686789 IDA NCBITaxon:10090 MGI:1858178 20110404 MGI:MGI PR:O88623-1 ubiquitin carboxyl-terminal hydrolase 2 isoform 1 (mouse) mUSP2/iso:1|Usp2-69 (mouse) located_in GO:0048471 perinuclear region of cytoplasm MGI_ref:3624565|PMID:14686789 IDA NCBITaxon:10090 MGI:1858178 20110404 MGI:MGI PR:O88623-2 ubiquitin carboxyl-terminal hydrolase 2 isoform 2 (mouse) mUSP2/iso:2|Usp2-45 (mouse) located_in GO:0005634 nucleus MGI_ref:5528783|PMID:24005904 IDA NCBITaxon:10090 MGI:1858178 20140717 MGI:MGI PR:O88623-2 ubiquitin carboxyl-terminal hydrolase 2 isoform 2 (mouse) mUSP2/iso:2|Usp2-45 (mouse) located_in GO:0005737 cytoplasm MGI_ref:5528783|PMID:24005904 IDA NCBITaxon:10090 MGI:1858178 20140717 MGI:MGI PR:O88703-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 (mouse) mHCN2/iso:1 located_in GO:0009986 cell surface PMID:12034718|PMID:15564593 IDA NCBITaxon:10090 UniProtKB:O88703-1 20080601 PRO:CNA PR:O88703-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 (mouse) mHCN2/iso:1 part_of GO:0032991 protein-containing complex PMID:12034718 IDA NCBITaxon:10090 UniProtKB:O88703-1 20080601 PRO:CNA PR:O88703-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform 1 (mouse) mHCN2/iso:1 contributes_to enables GO:0005222 intracellularly cAMP-activated cation channel activity PMID:11459060 IDA NCBITaxon:10090 UniProtKB:O88703-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 enables GO:0005261 monoatomic cation channel activity PMID:9630217 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 enables GO:0022843 voltage-gated monoatomic cation channel activity PMID:9634236 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 located_in GO:0009986 cell surface PMID:15564593 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 located_in GO:0030424 axon PMID:15479642 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 part_of GO:0032991 protein-containing complex PMID:12034718 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 acts_upstream_of_or_within GO:0006812 monoatomic cation transport PMID:9630217 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88704-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse) mHCN1/iso:1 contributes_to enables GO:0005222 intracellularly cAMP-activated cation channel activity PMID:11459060|PMID:9630217 IDA NCBITaxon:10090 UniProtKB:O88704-1 20080601 PRO:CNA PR:O88898-1 tumor protein 63 isoform 1 (mouse) mTP63/iso:1|TA*-alpha (mouse)|TA*p63alpha (mouse)|TAp63alpha (mouse) located_in GO:0005634 nucleus MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20140926 MGI:MGI PR:O88898-1 tumor protein 63 isoform 1 (mouse) mTP63/iso:1|TA*-alpha (mouse)|TA*p63alpha (mouse)|TAp63alpha (mouse) acts_upstream_of_or_within GO:0008544 epidermis development MGI_ref:3761221|PMID:16601749 IMP NCBITaxon:10090 MGI_allele:1934269 MGI:1330810 20080306 MGI:MGI results_in_development_of(MA:0000153) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 enables GO:0003682 chromatin binding MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20080306 MGI:MGI has_participant(MGI:MGI:96688) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 enables GO:0043565 sequence-specific DNA binding MGI_ref:3623698|PMID:16618808 IDA NCBITaxon:10090 MGI:1330810 20080221 MGI:MGI occurs_in(CL:0000312),has_input(MGI:MGI:104853) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 enables GO:0043565 sequence-specific DNA binding MGI_ref:3794467|PMID:18326838 IDA NCBITaxon:10090 MGI:1330810 20140519 MGI:MGI has_direct_input(MGI:101926)|has_direct_input(MGI:101927) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 located_in GO:0005634 nucleus MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20080306 MGI:MGI PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3623698|PMID:16618808 IGI NCBITaxon:10090 MGI:97363 MGI:1330810 20080221 MGI:MGI occurs_in(CL:0000312),has_regulation_target(MGI:MGI:104853) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3623698|PMID:16618808 IMP NCBITaxon:10090 MGI:1330810 20080221 MGI:MGI occurs_in(CL:0000312),has_regulation_target(MGI:MGI:104853) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0002064 epithelial cell development MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20090410 MGI:MGI occurs_in(MA:0000804),results_in_development_of(CL:0000312)|occurs_in(MA:0000805),results_in_development_of(CL:0000312)|results_in_development_of(CL:0000312),occurs_in(MA:0000806)|results_in_development_of(CL:0000312),occurs_in(MA:0000807) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0008544 epidermis development MGI_ref:3761221|PMID:16601749 IMP NCBITaxon:10090 MGI_allele:1934269 MGI:1330810 20140926 MGI:MGI results_in_development_of(MA:0000153) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0043616 keratinocyte proliferation MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20080306 MGI:MGI occurs_in(MA:0000803),acts_on_population_of(CL:0000312)|occurs_in(MA:0000803),acts_on_population_of(CL:0000646) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0045617 negative regulation of keratinocyte differentiation MGI_ref:3623698|PMID:16618808 IGI NCBITaxon:10090 MGI:97363 MGI:1330810 20080221 MGI:MGI regulates_o_results_in_acquisition_of_features_of(CL:0000312) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:2664466|PMID:12789272 IDA NCBITaxon:10090 MGI:1330810 20080129 MGI:MGI regulates_o_occurs_in(CL:0000312) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3696305|PMID:17093266 IDA NCBITaxon:10090 MGI:1330810 20080306 MGI:MGI regulates_o_occurs_in(MA:0000153),regulates_o_occurs_in(CL:0000312),has_regulation_target(MGI:MGI:99484) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3761221|PMID:16601749 IDA NCBITaxon:10090 MGI:1330810 20080306 MGI:MGI has_regulation_target(MGI:MGI:96688) PR:O88898-2 tumor protein 63 isoform 2 (mouse) DeltaN-alpha (mouse)|mTP63/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3794467|PMID:18326838 IDA NCBITaxon:10090 MGI:1330810 20140519 MGI:MGI has_regulation_target(MGI:101926)|has_regulation_target(MGI:101927) PR:O88917-2 adhesion G protein-coupled receptor L1 isoform 2 (rat) adhesion G protein-coupled receptor L1 isoform CL1AA (rat)|rADGRL1/iso:2 enables GO:0016524 latrotoxin receptor activity PMID:9208860 IDA NCBITaxon:10116 UniProtKB:O88917-2 20080915 PRO:CNA PR:O88917-3 adhesion G protein-coupled receptor L1 isoform 3 (rat) adhesion G protein-coupled receptor L1 isoform CL1AB (rat)|rADGRL1/iso:3 enables GO:0016524 latrotoxin receptor activity PMID:9208860 IDA NCBITaxon:10116 UniProtKB:O88917-3 20080915 PRO:CNA PR:O88917-4 adhesion G protein-coupled receptor L1 isoform 4 (rat) adhesion G protein-coupled receptor L1 isoform CL1BA (rat)|rADGRL1/iso:4 enables GO:0016524 latrotoxin receptor activity PMID:9208860 IDA NCBITaxon:10116 UniProtKB:O88917-4 20080915 PRO:CNA PR:O88935 synapsin-1 (mouse) mSYN1|Syn-1|Syn1|synapsin I (mouse) acts_upstream_of_or_within GO:0007269 neurotransmitter secretion PMID:7777057 IMP NCBITaxon:10090 MGI:103020 UniProtKB:O88935 20100420 PRO:HJD PR:O88935 synapsin-1 (mouse) mSYN1|Syn-1|Syn1|synapsin I (mouse) acts_upstream_of_or_within GO:0007269 neurotransmitter secretion PMID:7777057 IMP NCBITaxon:10090 MGI_allele:1857250 UniProtKB:O88935 20100420 PRO:HJD PR:O88935-1 synapsin-1 isoform 1b (mouse) mSYN1/iso:1b|Syn1 isoform 2 (mouse)|synapsin-1 isoform 2 (mouse) enables GO:0005515 protein binding PR:P04925 MGI_ref:2153789|PMID:11571277 IPI NCBITaxon:10090 UniProtKB:O88935-1 20100415 MGI:MGI PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) enables GO:0005515 protein binding PR:P04925 PMID:11571277 IPI NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) part_of GO:0000795 synaptonemal complex PMID:14736746 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) located_in GO:0030672 synaptic vesicle membrane PMID:15071120 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) located_in GO:0045202 synapse PMID:16025111 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) located_in GO:0045202 synapse PMID:16818724 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) located_in GO:0045202 synapse PMID:17018287 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88935-2 synapsin-1 isoform 1a (mouse) mSYN1/iso:1a|Syn1 isoform 1 (mouse)|synapsin-1 isoform 1 (mouse) located_in GO:0048786 presynaptic active zone PMID:16621800 EXP NCBITaxon:10090 UniProtKB:O88935-2 20100420 PRO:HJD PR:O88943-1 potassium voltage-gated channel subfamily KQT member 2 isoform A (rat) rKCNQ2/iso:A contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:11038262 IDA NCBITaxon:10116 UniProtKB:O88943-1 20080601 PRO:CNA PR:O88998-1 noelin isoform 1 (mouse) mOLFM1/iso:1|pancortin isoform BMZ (mouse)|pancortin-1 (mouse) enables GO:0001540 amyloid-beta binding MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-1 noelin isoform 1 (mouse) mOLFM1/iso:1|pancortin isoform BMZ (mouse)|pancortin-1 (mouse) acts_upstream_of_or_within GO:1902003 regulation of amyloid-beta formation MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-1 noelin isoform 1 (mouse) mOLFM1/iso:1|pancortin isoform BMZ (mouse)|pancortin-1 (mouse) acts_upstream_of_or_within GO:1902430 negative regulation of amyloid-beta formation MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20131002 MGI:MGI PR:O88998-2 noelin isoform 2 (mouse) mOLFM1/iso:2|pancortin isoform BMY (mouse)|pancortin-2 (mouse) enables GO:0001540 amyloid-beta binding MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-2 noelin isoform 2 (mouse) mOLFM1/iso:2|pancortin isoform BMY (mouse)|pancortin-2 (mouse) acts_upstream_of_or_within GO:1902003 regulation of amyloid-beta formation MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-2 noelin isoform 2 (mouse) mOLFM1/iso:2|pancortin isoform BMY (mouse)|pancortin-2 (mouse) acts_upstream_of_or_within GO:2001223 negative regulation of neuron migration MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI regulates_o_results_in_movement_of(CL:0002609) PR:O88998-3 noelin isoform 3 (mouse) mOLFM1/iso:3|pancortin isoform AMZ (mouse)|pancortin-3 (mouse) enables GO:0001540 amyloid-beta binding MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-3 noelin isoform 3 (mouse) mOLFM1/iso:3|pancortin isoform AMZ (mouse)|pancortin-3 (mouse) located_in GO:0005615 extracellular space MGI_ref:3611587|PMID:15927402 IDA NCBITaxon:10090 MGI:1860437 20080807 MGI:MGI PR:O88998-3 noelin isoform 3 (mouse) mOLFM1/iso:3|pancortin isoform AMZ (mouse)|pancortin-3 (mouse) acts_upstream_of_or_within GO:0051259 protein complex oligomerization MGI_ref:3611587|PMID:15927402 IDA NCBITaxon:10090 MGI:1860437 20080813 MGI:MGI PR:O88998-4 noelin isoform 4 (mouse) mOLFM1/iso:4|pancortin isoform AMY (mouse)|pancortin-4 (mouse) enables GO:0001540 amyloid-beta binding MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI PR:O88998-4 noelin isoform 4 (mouse) mOLFM1/iso:4|pancortin isoform AMY (mouse)|pancortin-4 (mouse) located_in GO:0005615 extracellular space MGI_ref:3611587|PMID:15927402 IDA NCBITaxon:10090 MGI:1860437 20140428 MGI:MGI PR:O88998-4 noelin isoform 4 (mouse) mOLFM1/iso:4|pancortin isoform AMY (mouse)|pancortin-4 (mouse) acts_upstream_of_or_within GO:2001223 negative regulation of neuron migration MGI_ref:5444053|PMID:22992957 IDA NCBITaxon:10090 MGI:1860437 20130925 MGI:MGI regulates_o_results_in_movement_of(CL:0002609) PR:O89096 fibroblast growth factor 14 isoform 3 (mouse) FGF-14b (mouse)|mFGF14/iso:3 acts_upstream_of_or_within GO:1901843 positive regulation of high voltage-gated calcium channel activity MGI_ref:5510622|PMID:23831029 IDA NCBITaxon:10090 MGI:109189 20141021 MGI:MGI PR:O89109-1 intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (mouse) mKCNN4/iso:1 enables GO:0015269 calcium-activated potassium channel activity PMID:11724775 IDA NCBITaxon:10090 UniProtKB:O89109-1 20080915 PRO:CNA PR:O89109-1 intermediate conductance calcium-activated potassium channel protein 4 isoform 1 (mouse) mKCNN4/iso:1 acts_upstream_of_or_within GO:0050714 positive regulation of protein secretion PMID:11724775 IDA NCBITaxon:10090 UniProtKB:O89109-1 20080915 PRO:CNA PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 enables GO:0005515 protein binding PR:O42860 PMID:22660415 IPI NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 located_in GO:0000776 kinetochore PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Timing=spindle disruption. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 located_in GO:0000779 condensed chromosome, centromeric region PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Timing=Meiosis I. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0007059 chromosome segregation PMID:22660415 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0007094 mitotic spindle assembly checkpoint signaling PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Target=PR:O14417. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Target=PR:P36626. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22660415 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Target=PR:O42860. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22660415 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Target=PR:O59767. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22660415 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER Target=PR:P87169. PR:O94751 checkpoint serine/threonine-protein kinase bub1 (Schizosaccharomyces pombe 972h-) bub1|SPCC1322.12c|Spom972h-bub1 acts_upstream_of_or_within GO:0045143 homologous chromosome segregation PMID:12606573 EXP NCBITaxon:284812 UniProtKB:O94751 20130102 PRO:KER PR:O95259-2 potassium voltage-gated channel subfamily H member 1 isoform 1 (human) hKCNH1/iso:1|potassium voltage-gated channel subfamily H member 1 isoform hEAG (human) enables GO:0005251 delayed rectifier potassium channel activity PMID:9738473 IDA NCBITaxon:9606 UniProtKB:O95259-2 20080601 PRO:CNA PR:O95259-2 potassium voltage-gated channel subfamily H member 1 isoform 1 (human) hKCNH1/iso:1|potassium voltage-gated channel subfamily H member 1 isoform hEAG (human) enables GO:0005516 calmodulin binding PMID:10880439 IDA NCBITaxon:9606 UniProtKB:O95259-2 20080601 PRO:CNA PR:O95259-2 potassium voltage-gated channel subfamily H member 1 isoform 1 (human) hKCNH1/iso:1|potassium voltage-gated channel subfamily H member 1 isoform hEAG (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:11943152|PMID:9738473 IDA NCBITaxon:9606 PR:000000794 UniProtKB:O95259-2 20080601 PRO:CNA PR:O95259-2 potassium voltage-gated channel subfamily H member 1 isoform 1 (human) hKCNH1/iso:1|potassium voltage-gated channel subfamily H member 1 isoform hEAG (human) acts_upstream_of_or_within GO:0007520 myoblast fusion PMID:9738473 IDA NCBITaxon:9606 UniProtKB:O95259-2 20080601 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 enables GO:0005515 protein binding PR:000025960 PMID:11877415|PMID:9865696 IPI NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 enables GO:0005515 protein binding PR:P08100 PMID:17693260 IPI NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 located_in GO:0005769 early endosome PMID:11877415|PMID:12356868|PMID:12432064 IDA NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 acts_upstream_of_or_within GO:0006897 endocytosis PMID:12809483 IDA NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10615055 IDA NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PMID:11877415|PMID:12356868 IDA NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human) hZFYVE9/iso:1 acts_upstream_of_or_within GO:0060390 regulation of SMAD protein signal transduction PMID:11877415|PMID:12356868 IDA NCBITaxon:9606 UniProtKB:O95405-1 20080301 PRO:CNA PR:O95405-2 zinc finger FYVE domain-containing protein 9 isoform 2 (human) hZFYVE9/iso:2 located_in GO:0005615 extracellular space PMID:9582421 IDA NCBITaxon:9606 UniProtKB:O95405-2 20080301 PRO:CNA PR:O95405-3 zinc finger FYVE domain-containing protein 9 isoform 3 (human) hZFYVE9/iso:3 located_in GO:0005615 extracellular space PMID:9582421 IDA NCBITaxon:9606 UniProtKB:O95405-3 20080301 PRO:CNA PR:O95644-1 nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human) hNFATC1/iso:C-alpha enables GO:0005515 protein binding PR:P45983 PMID:10866678 IPI NCBITaxon:9606 UniProtKB:O95644-1 20090714 PRO:JAN Note=Binding to CRM1 increases when coexpressed with calcineurin and JIP-1 PR:O95644-1 nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human) hNFATC1/iso:C-alpha located_in GO:0005634 nucleus PMID:10866678 EXP NCBITaxon:9606 UniProtKB:O95644-1 20090714 PRO:JAN PR:O95644-1 nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human) hNFATC1/iso:C-alpha increased enables GO:0005515 protein binding PR:000036638 PR:O14980 PMID:10866678 IPI NCBITaxon:9606 UniProtKB:O95644-1 20090714 PRO:JAN Note=Binding to CRM1 increases when coexpressed with calcineurin and JIP-1 PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse) LDH-C (mouse)|mLDHC/iso:1 enables GO:0004459 L-lactate dehydrogenase activity PMID:18367675 EXP NCBITaxon:10090 UniProtKB:P00342-1 20120221 PRO:HJD PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse) LDH-C (mouse)|mLDHC/iso:1 located_in GO:0005737 cytoplasm PMID:18367675 EXP NCBITaxon:10090 UniProtKB:P00342-1 20120221 PRO:HJD PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse) LDH-C (mouse)|mLDHC/iso:1 located_in GO:0031514 motile cilium PMID:18367675 EXP NCBITaxon:10090 UniProtKB:P00342-1 20120221 PRO:HJD PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse) LDH-C (mouse)|mLDHC/iso:1 acts_upstream_of_or_within GO:0006090 pyruvate metabolic process PMID:18367675 EXP NCBITaxon:10090 UniProtKB:P00342-1 20120221 PRO:HJD PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse) LDH-C (mouse)|mLDHC/iso:1 acts_upstream_of_or_within GO:0019516 lactate oxidation PMID:18367675 EXP NCBITaxon:10090 UniProtKB:P00342-1 20120221 PRO:HJD PR:P00915-1 carbonic anhydrase 1 isoform 1 (human) hCA1/iso:1 has_role CHEBI:59163 biomarker PMID:17968930 EXP NCBITaxon:9606 UniProtKB:P00915-1 20100525 SALO:AJ PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 enables GO:0005515 protein binding PMID:12706874 IPI NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 part_of GO:0005667 transcription factor complex PMID:16908182|PMID:2006410 IDA NCBITaxon:9606 UniProtKB:P61244 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 acts_upstream_of_or_within GO:0006357 regulation of transcription by RNA polymerase II PMID:16908182|PMID:2006410 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:10962037 TAS NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 acts_upstream_of_or_within GO:0008283 cell population proliferation PMID:10962037 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-1 c-myc protein isoform 1 (human) hMYC/iso:1 contributes_to enables GO:0003700 DNA-binding transcription factor activity PMID:16908182|PMID:2006410 IDA NCBITaxon:9606 UniProtKB:P01106-1 20080301 PRO:CNA PR:P01106-2 c-myc protein isoform 2 (human) hMYC/iso:2 contributes_to enables GO:0003700 DNA-binding transcription factor activity PMID:3277717 IDA NCBITaxon:9606 UniProtKB:P01106-2 20080301 PRO:CNA PR:P01108-1 c-myc protein isoform 1 (mouse) mMYC/iso:1 located_in GO:0005634 nucleus PMID:15503302|PMID:16908182 IDA NCBITaxon:10090 UniProtKB:P01108-1 20080301 PRO:CNA PR:P01137-1 transforming growth factor beta-1 isoform 1 (human) hTGFB1/iso:1 enables GO:0042803 protein homodimerization activity PMID:1544940 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:P01137-1 transforming growth factor beta-1 isoform 1 (human) hTGFB1/iso:1 located_in GO:0005796 Golgi lumen PMID:1544940 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:P01137-1 transforming growth factor beta-1 isoform 1 (human) hTGFB1/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:1544940 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:P01137-1 transforming growth factor beta-1 isoform 1 (human) hTGFB1/iso:1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:9918798 IDA NCBITaxon:9606 UniProtKB:P01137-1 20080301 PRO:CNA PR:P01375-1 tumor necrosis factor isoform 1 (human) hTNF/iso:1 located_in GO:0005886 plasma membrane PMID:3349526 IDA NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:P01375-1 tumor necrosis factor isoform 1 (human) hTNF/iso:1 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:3856324 IDA NCBITaxon:9606 UniProtKB:P01375-1 20080301 PRO:CNA PR:P01580-1 interferon gamma isoform 1 (mouse) mIFNG/iso:1 acts_upstream_of_or_within GO:0042742 defense response to bacterium PMID:17661079 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA PR:P01580-1 interferon gamma isoform 1 (mouse) mIFNG/iso:1 acts_upstream_of_or_within GO:0032722 positive regulation of chemokine production PMID:12925700 IDA NCBITaxon:10090 UniProtKB:P01580-1 20080301 PRO:CNA PR:P01584-1 interleukin-1 beta isoform 1 (human) hIL1B/iso:1 has_role CHEBI:59163 biomarker PMID:15623624 EXP NCBITaxon:9606 UniProtKB:P01584-1 20100525 SALO:AJ PR:P01730 T-cell surface glycoprotein CD4 (human) CD4|hCD4|T-cell surface antigen T4/Leu-3 (human) enables GO:0005515 protein binding PR:P05879 PMID:9269777 IPI NCBITaxon:9606 UniProtKB:P01730 20090717 PRO:CL Note=Binding between proteins from heterogeneous species PR:P01730 T-cell surface glycoprotein CD4 (human) CD4|hCD4|T-cell surface antigen T4/Leu-3 (human) acts_upstream_of_or_within GO:0090630 activation of GTPase activity PMID:9269777 EXP NCBITaxon:9606 UniProtKB:P01730 20090717 PRO:CL PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A enables GO:0005198 structural molecule activity PMID:3453101 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A enables GO:0005198 structural molecule activity PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A enables GO:0005515 protein binding PR:P03247-1 PMID:10381623 IPI NCBITaxon:9606 UniProtKB:P02545-1 20061215 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A located_in GO:0005635 nuclear envelope PMID:3453101 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A located_in GO:0005638 lamin filament PMID:10080180 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A located_in GO:0005652 nuclear lamina PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A located_in GO:0005882 intermediate filament PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A located_in GO:0048471 perinuclear region of cytoplasm PMID:10080180 IDA NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-1 prelamin-A/C isoform A (human) hLMNA/iso:A acts_upstream_of_or_within GO:0007517 muscle organ development PMID:10080180 IMP NCBITaxon:9606 UniProtKB:P02545-1 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C enables GO:0005198 structural molecule activity PMID:3453101 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C enables GO:0005198 structural molecule activity PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C enables GO:0005515 protein binding PR:O60238 PMID:10381623 IPI NCBITaxon:9606 UniProtKB:P02545-2 20061215 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C enables GO:0005515 protein binding PR:P03247-1 PMID:10381623 IPI NCBITaxon:9606 UniProtKB:P02545-2 20061215 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C located_in GO:0005635 nuclear envelope PMID:3453101 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C located_in GO:0005638 lamin filament PMID:10080180 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C located_in GO:0005652 nuclear lamina PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C located_in GO:0005882 intermediate filament PMID:8344919 TAS NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C located_in GO:0048471 perinuclear region of cytoplasm PMID:10080180 IDA NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P02545-2 prelamin-A/C isoform C (human) hLMNA/iso:C acts_upstream_of_or_within GO:0007517 muscle organ development PMID:10080180 IMP NCBITaxon:9606 UniProtKB:P02545-2 20060523 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P03971-1 Muellerian-inhibiting factor isoform 1 (human) hAMH/iso:1 acts_upstream_of_or_within GO:0001880 Mullerian duct regression PMID:14750901 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:P03971-1 Muellerian-inhibiting factor isoform 1 (human) hAMH/iso:1 acts_upstream_of_or_within GO:0007548 sex differentiation PMID:12834017 IDA NCBITaxon:9606 UniProtKB:P03971-1 20080301 PRO:CNA PR:P04040-1 catalase isoform 1 (human) hCAT/iso:1 has_role CHEBI:59163 biomarker PMID:18829504 EXP NCBITaxon:9606 UniProtKB:P04040-1 20100525 SALO:AJ PR:P04049 RAF proto-oncogene serine/threonine-protein kinase (human) cRaf (human)|hRAF1|proto-oncogene c-RAF (human)|RAF|Raf-1 (human)|RAF1 enables GO:0005515 protein binding PR:O60566 PMID:20703093 IPI NCBITaxon:9606 UniProtKB:P04049 20121112 PRO:KER PR:P04049 RAF proto-oncogene serine/threonine-protein kinase (human) cRaf (human)|hRAF1|proto-oncogene c-RAF (human)|RAF|Raf-1 (human)|RAF1 acts_upstream_of_or_within GO:0032877 positive regulation of DNA endoreduplication PMID:20703093 EXP NCBITaxon:9606 UniProtKB:P04049 20121112 PRO:KER PR:P04202-1 transforming growth factor beta-1 isoform 1 (mouse) mTGFB1/iso:1 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 IDA NCBITaxon:10090 UniProtKB:P04202-1 20080301 PRO:CNA PR:P04637-1 cellular tumor antigen p53 isoform 1 (human) hTP53/iso:1 enables GO:0005515 protein binding PR:O43683 PMID:19252416 IPI NCBITaxon:9606 UniProtKB:P04637-1 20121105 PRO:KER Timing=metaphase and spindle depolymerization (nocodazole) PR:P04637-1 cellular tumor antigen p53 isoform 1 (human) hTP53/iso:1 enables GO:0005515 protein binding PR:O60566 PMID:17671183 IPI NCBITaxon:9606 UniProtKB:P04637-1 20121105 PRO:KER Timing=metaphase and spindle depolymerization (nocodazole) PR:P05549-1 transcription factor AP-2-alpha isoform 1 (human) AP-2A (human)|hTFAP2A/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8321221 EXP NCBITaxon:9606 UniProtKB:P05549-1 20121119 PRO:AAA PR:P05549-2 transcription factor AP-2-alpha isoform 4 (human) AP-2B (human)|hTFAP2A/iso:4 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:8321221 EXP NCBITaxon:9606 UniProtKB:P05549-2 20121119 PRO:AAA PR:P05627 transcription factor Jun (mouse) activator protein 1 (mouse)|AH119 (mouse)|AP1 (mouse)|Jun|Jun A (mouse)|mJUN|proto-oncogene c-Jun (mouse)|V-jun avian sarcoma virus 17 oncogene homolog (mouse) enables GO:0005515 protein binding PR:Q60739-1 MGI_ref:4819895|PMID:20516211 IPI NCBITaxon:10090 MGI:96646 20100826 MGI:MGI PR:P05771-1 protein kinase C beta type isoform Beta-I (human) hPRKCB/iso:Beta-I|protein kinase C beta type isoform PRKCB1 (human) located_in GO:0016020 membrane MGI_ref:3847400|PMID:18323529 IDA NCBITaxon:10090 MGI:97596 20141022 MGI:MGI PR:P05771-1 protein kinase C beta type isoform Beta-I (human) hPRKCB/iso:Beta-I|protein kinase C beta type isoform PRKCB1 (human) NOT acts_upstream_of_or_within GO:0001666 response to hypoxia MGI_ref:3847400|PMID:18323529 IDA NCBITaxon:10090 MGI:97596 20141022 MGI:MGI PR:P05771-2 protein kinase C beta type isoform Beta-II (human) hPRKCB/iso:Beta-II|protein kinase C beta type isoform PRKCB2 (human) located_in GO:0016020 membrane MGI_ref:3847400|PMID:18323529 IDA NCBITaxon:10090 MGI:97596 20150410 MGI:MGI PR:P05771-2 protein kinase C beta type isoform Beta-II (human) hPRKCB/iso:Beta-II|protein kinase C beta type isoform PRKCB2 (human) acts_upstream_of_or_within GO:0001666 response to hypoxia MGI_ref:3847400|PMID:18323529 IDA NCBITaxon:10090 MGI:97596 20141022 MGI:MGI PR:P06537-2 glucocorticoid receptor isoform 2 (mouse) glucocorticoid receptor isoform 2-A (mouse)|glucocorticoid receptor isoform GR form B (mouse)|mNR3C1/iso:2 located_in GO:0005634 nucleus MGI_ref:5316956|PMID:20660300 IDA NCBITaxon:10090 MGI:95824 20140520 MGI:MGI PR:P06537-2 glucocorticoid receptor isoform 2 (mouse) glucocorticoid receptor isoform 2-A (mouse)|glucocorticoid receptor isoform GR form B (mouse)|mNR3C1/iso:2 located_in GO:0005737 cytoplasm MGI_ref:5316956|PMID:20660300 IDA NCBITaxon:10090 MGI:95824 20140520 MGI:MGI PR:P06537-2 glucocorticoid receptor isoform 2 (mouse) glucocorticoid receptor isoform 2-A (mouse)|glucocorticoid receptor isoform GR form B (mouse)|mNR3C1/iso:2 acts_upstream_of_or_within GO:1900170 negative regulation of glucocorticoid mediated signaling pathway MGI_ref:5316956|PMID:20660300 IDA NCBITaxon:10090 MGI:95824 20140520 MGI:MGI PR:P06702-1 protein S100-A9 isoform 1 (human) hS100A9/iso:1 has_role CHEBI:59163 biomarker PMID:18829504 EXP NCBITaxon:9606 UniProtKB:P06702-1 20100525 SALO:AJ PR:P06733 alpha-enolase (human) 2-phospho-D-glycerate hydro-lyase (human)|C-myc promoter-binding protein (human)|ENO1|ENO1L1|enolase 1 (human)|hENO1|MBP-1 (human)|MBPB1|MPB-1 (human)|MPB1|NNE (human)|non-neural enolase (human)|phosphopyruvate hydratase (human)|plasminogen-binding protein (human) has_role CHEBI:59163 biomarker PMID:17968930 EXP NCBITaxon:9606 UniProtKB:P06733 20100525 SALO:AJ PR:P06797-1 procathepsin L isoform 1 (mouse) cathepsin L1 pre-pro form (mouse)|cathepsin L1 precursor (mouse)|mCtsl/iso:1 acts_upstream_of_or_within GO:0016540 protein autoprocessing MGI_ref:5513110|PMID:1482371 IDA NCBITaxon:10090 MGI:88564 20131018 MGI:MGI PR:000050324 receptor-type tyrosine-protein phosphatase C isoform x1 (mouse) mPtprc/iso:x1|receptor-type tyrosine-protein phosphatase C isoform B220 (mouse)|UniProtKB:P06800-4, 3-1293 located_in GO:0009897 external side of plasma membrane MGI_ref:77755|PMID:8566025 IDA NCBITaxon:10090 MGI:97810 20080326 MGI:MGI part_of(CL:0000236)|part_of(CL:0000782)|part_of(CL:0000782) PR:P07585-1 decorin isoform A (human) hDCN/iso:A acts_upstream_of_or_within GO:0030199 collagen fibril organization PMID:17651433 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:P07585-1 decorin isoform A (human) hDCN/iso:A acts_upstream_of_or_within GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:11879191 IDA NCBITaxon:9606 UniProtKB:P07585-1 20080301 PRO:CNA PR:P07737-1 profilin-1 isoform 1 (human) hPFN1/iso:1 has_role CHEBI:59163 biomarker PMID:18829504 EXP NCBITaxon:9606 UniProtKB:P07737-1 20100525 SALO:AJ PR:P08047-1 transcription factor Sp1 isoform 1 (human) hSP1/iso:1|transcription factor Sp1 isoform Sp1a (human) located_in GO:0005634 nucleus PMID:2170018 IDA NCBITaxon:9606 UniProtKB:P08047-1 20080301 PRO:CNA PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:10704452 IMP NCBITaxon:10090 MGI_allele:1931056 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:16136673 IMP NCBITaxon:10090 MGI_allele:3574072 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0007622 rhythmic behavior PMID:8893031 IMP NCBITaxon:10090 MGI_allele:1857507 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0008045 motor neuron axon guidance PMID:9806922 IMP NCBITaxon:10090 MGI:96170 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0014037 Schwann cell differentiation PMID:16136673 IMP NCBITaxon:10090 MGI_allele:3574072 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0021569 rhombomere 3 development PMID:9806922 IMP NCBITaxon:10090 MGI:96170 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0021612 facial nerve structural organization PMID:9806922 IMP NCBITaxon:10090 MGI:96170 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0021660 rhombomere 3 formation PMID:7903221 IMP NCBITaxon:10090 MGI_allele:1857507 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0021666 rhombomere 5 formation PMID:7903221 IMP NCBITaxon:10090 MGI_allele:1857507 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0030278 regulation of ossification PMID:8565822 IMP NCBITaxon:10090 MGI_allele:1857507 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0042552 myelination PMID:10704452 IMP NCBITaxon:10090 MGI_allele:1931056 UniProtKB:P08152 20100215 PRO:HJD PR:P08152 E3 SUMO-protein ligase EGR2 (mouse) E3 SUMO-protein transferase ERG2 (mouse)|early growth response protein 2 (mouse)|Egr-2|EGR-2 (mouse)|Egr2|Krox-20|mEGR2|Zfp-25|zinc finger protein Krox-20 (mouse) acts_upstream_of_or_within GO:0042552 myelination PMID:16136673 IMP NCBITaxon:10090 MGI_allele:3574072 UniProtKB:P08152 20100215 PRO:HJD PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse) mEGR2/iso:Long enables GO:0003677 DNA binding PMID:8093858|PMID:8895582 IDA NCBITaxon:10090 UniProtKB:P08152-1 20100215 PRO:HJD PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse) mEGR2/iso:Long enables GO:0003700 DNA-binding transcription factor activity PMID:8093858 IDA NCBITaxon:10090 UniProtKB:P08152-1 20100215 PRO:HJD PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse) mEGR2/iso:Long located_in GO:0005634 nucleus PMID:15282162 IDA NCBITaxon:10090 UniProtKB:P08152-1 20100215 PRO:HJD PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse) mEGR2/iso:Long acts_upstream_of_or_within GO:0007622 rhythmic behavior PMID:8893031 IDA NCBITaxon:10090 UniProtKB:P08152-1 20100215 PRO:HJD PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse) mEGR2/iso:Long acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8093858 IDA NCBITaxon:10090 UniProtKB:P08152-1 20100215 PRO:HJD PR:P08152-2 E3 SUMO-protein ligase EGR2 isoform Short (mouse) mEGR2/iso:Short enables GO:0005515 protein binding PR:Q8C5D8-1 MGI_ref:3629292|PMID:16675951 IPI NCBITaxon:10090 MGI:97858 MGI:95296 20091104 MGI:MGI PR:P08152-2 E3 SUMO-protein ligase EGR2 isoform Short (mouse) mEGR2/iso:Short located_in GO:0005634 nucleus MGI_ref:3629292|PMID:16675951 IDA NCBITaxon:10090 MGI:97858 MGI:95296 20091104 MGI:MGI PR:P08401-1 sensor protein CreC isoform 1 (Escherichia coli K-12) Ec-creC/iso:1 enables GO:0004673 protein histidine kinase activity PMID:15522865 EXP NCBITaxon:83333 UniProtKB:P08401-1 20100331 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0001541 ovarian follicle development PMID:9166111 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:3267209 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:12456957 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0007399 nervous system development PMID:10320815 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0030154 cell differentiation PMID:12456957 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08476-1 inhibin beta A chain isoform 1 (human) hINHBA/iso:1 acts_upstream_of_or_within GO:0050789 regulation of biological process PMID:12419948|PMID:3122219 IDA NCBITaxon:9606 UniProtKB:P08476-1 20080301 PRO:CNA PR:P08571 monocyte differentiation antigen CD14 (human) CD14|hCD14|myeloid cell-specific leucine-rich glycoprotein (human) NOT expressed_in CL:0000127 astrocyte PMID:24659539 EXP NCBITaxon:9606 UniProtKB:P08571 20140514 PRO:CNA PR:P09055-1 integrin beta-1 isoform beta-1A (mouse) mITGB1/iso:beta-1A acts_upstream_of_or_within GO:0016477 cell migration MGI_ref:1203253|PMID:9553049 IMP NCBITaxon:10090 MGI_allele:2154544 MGI:96610 20130913 MGI:MGI results_in_movement_of(CL:0000057) PR:P09055-2 integrin beta-1 isoform beta-1D (mouse) mITGB1/iso:beta-1D acts_upstream_of_or_within GO:0048738 cardiac muscle tissue development MGI_ref:1203253|PMID:9553049 IMP NCBITaxon:10090 MGI_allele:2154543 MGI:96610 20130913 MGI:MGI results_in_development_of(MA:0000164) PR:P09631-1 homeobox protein Hox-A9 isoform HoxA-9 (mouse) mHOXA9/iso:HoxA-9 located_in GO:0005634 nucleus MGI_ref:3032461|PMID:15161102 IDA NCBITaxon:10090 MGI:96180 20080811 MGI:MGI PR:P09631-2 homeobox protein Hox-A9 isoform HoxA-9T (mouse) mHOXA9/iso:HoxA-9T located_in GO:0005634 nucleus MGI_ref:3032461|PMID:15161102 IDA NCBITaxon:10090 MGI:96180 20140327 MGI:MGI PR:P09631-2 homeobox protein Hox-A9 isoform HoxA-9T (mouse) mHOXA9/iso:HoxA-9T located_in GO:0005737 cytoplasm MGI_ref:3032461|PMID:15161102 IDA NCBITaxon:10090 MGI:96180 20080804 MGI:MGI PR:P0AC86 glycogen phosphorylase (Escherichia coli K-12) b3428|Ec-glgP|glgP|glgY|JW3391 enables GO:0005515 protein binding PR:000025906 PMID:9334229 IPI NCBITaxon:83333 UniProtKB:P0AC86 20101005 PRO:CNA PR:P0C605-1 cGMP-dependent protein kinase 1 isoform Alpha (mouse) cGMP-dependent protein kinase 1 isoform CGK1-alpha (mouse)|mPRKG1/iso:Alpha enables GO:0004674 protein serine/threonine kinase activity MGI_ref:5447879|PMID:22922339 IDA NCBITaxon:10090 MGI:108174 20150121 MGI:MGI has_input(UniProtKB:P70460),has_output(PR:000044496) PR:P0C605-1 cGMP-dependent protein kinase 1 isoform Alpha (mouse) cGMP-dependent protein kinase 1 isoform CGK1-alpha (mouse)|mPRKG1/iso:Alpha acts_upstream_of_or_within GO:0006468 protein phosphorylation MGI_ref:5447879|PMID:22922339 IDA NCBITaxon:10090 MGI:108174 20150121 MGI:MGI has_input(UniProtKB:P70460),has_output(PR:000044496) PR:P10145 interleukin-8 (human) C-X-C motif chemokine 8 (human)|chemokine (C-X-C motif) ligand 8 (human)|CXCL8|emoctakin (human)|GCP-1 (human)|granulocyte chemotactic protein 1 (human)|hCXCL8|IL-8 (human)|IL8|MDNCF (human)|MONAP (human)|monocyte-derived neutrophil chemotactic factor (human)|monocyte-derived neutrophil-activating peptide (human)|NAP-1 (human)|neutrophil-activating protein 1 (human)|protein 3-10C (human)|T-cell chemotactic factor (human) has_role CHEBI:59163 biomarker PMID:15623624 EXP NCBITaxon:9606 UniProtKB:P10145 20100525 SALO:AJ PR:P10415-1 apoptosis regulator Bcl-2 isoform Alpha (human) hBCL2/iso:Alpha enables GO:0005515 protein binding PR:P63328 PMID:9109491 IPI NCBITaxon:9606 UniProtKB:P10415-1 20090918 PRO:JAN Note=Binding between proteins from heterogeneous species PR:P10415-1 apoptosis regulator Bcl-2 isoform Alpha (human) hBCL2/iso:Alpha enables GO:0005515 protein binding PR:Q07813 PMID:9109491 IPI NCBITaxon:9606 UniProtKB:P10415-1 20090918 PRO:JAN Note=Binding between proteins from heterogeneous species PR:P10415-1 apoptosis regulator Bcl-2 isoform Alpha (human) hBCL2/iso:Alpha located_in GO:0005886 plasma membrane PMID:9109491 EXP NCBITaxon:9606 UniProtKB:P10415-1 20090918 PRO:JAN PR:P10415-1 apoptosis regulator Bcl-2 isoform Alpha (human) hBCL2/iso:Alpha acts_upstream_of_or_within GO:0070885 negative regulation of calcineurin-NFAT signaling cascade PMID:9109491 EXP NCBITaxon:9606 UniProtKB:P10415-1 20090918 PRO:JAN PR:P10417-1 apoptosis regulator Bcl-2 isoform Alpha (mouse) mBCL2/iso:Alpha enables GO:0005515 protein binding PR:000026785 PMID:11583631 IPI NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:P10417-1 apoptosis regulator Bcl-2 isoform Alpha (mouse) mBCL2/iso:Alpha acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:11583631 EXP NCBITaxon:10090 UniProtKB:P10417-1 20090918 PRO:JAN PR:P10600-1 transforming growth factor beta-3 isoform 1 (human) hTGFB3/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:3164476 TAS NCBITaxon:9606 UniProtKB:P10600-1 20080301 PRO:CNA PR:P10600-1 transforming growth factor beta-3 isoform 1 (human) hTGFB3/iso:1 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:3164476 TAS NCBITaxon:9606 UniProtKB:P10600-1 20080301 PRO:CNA PR:P10665 ribosomal protein S6 kinase 2 alpha (frog) frog-rps6ka|MAP kinase-activated protein kinase 1 (frog)|MAPK-activated protein kinase 1 (frog)|MAPKAP kinase 1 (frog)|MAPKAPK-1 (frog)|p90-RSK (frog)|ribosomal protein S6 kinase II alpha (frog)|rps6ka|S6KII-alpha (frog) enables GO:0016301 kinase activity PMID:11231148 EXP NCBITaxon:8355 UniProtKB:P10665 20120912 PRO:KER PR:P10810 monocyte differentiation antigen CD14 (mouse) Cd14|CD14 (mouse)|mCD14|myeloid cell-specific leucine-rich glycoprotein (mouse) expressed_in CL:0000127 astrocyte PMID:24659539 EXP NCBITaxon:10090 UniProtKB:P10810 20140514 PRO:CNA PR:P11035 nitrate reductase [NADH] 2 (Arabidopsis thaliana) At-NR2|At1g37130|CHL3|F28L22.2|NIA2|NR2 (Arabidopsis thaliana) enables GO:0005515 protein binding PR:Q39026 PMID:20870959 IPI NCBITaxon:3702 UniProtKB:P11035 20140415 PRO:LVM PR:P11035 nitrate reductase [NADH] 2 (Arabidopsis thaliana) At-NR2|At1g37130|CHL3|F28L22.2|NIA2|NR2 (Arabidopsis thaliana) enables GO:0008940 nitrate reductase activity PMID:20870959 EXP NCBITaxon:3702 UniProtKB:P11035 20140415 PRO:LVM PR:P11035 nitrate reductase [NADH] 2 (Arabidopsis thaliana) At-NR2|At1g37130|CHL3|F28L22.2|NIA2|NR2 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0006809 nitric oxide biosynthetic process PMID:20870959 IMP NCBITaxon:3702 UniProtKB:P11035 20140415 PRO:LVM PR:P11035 nitrate reductase [NADH] 2 (Arabidopsis thaliana) At-NR2|At1g37130|CHL3|F28L22.2|NIA2|NR2 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0042542 response to hydrogen peroxide PMID:20870959 IMP NCBITaxon:3702 UniProtKB:P11035 20140415 PRO:LVM PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara enables GO:0043565 sequence-specific DNA binding PMID:7823919 IMP NCBITaxon:10090 MGI:98214|MGI:98215|MGI:98216 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:7566114 IMP NCBITaxon:10090 MGI:1349717 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0001657 ureteric bud development PMID:12195422 IMP NCBITaxon:10090 MGI_allele:1857622 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0007283 spermatogenesis MGI_ref:61760|PMID:8394014 IMP NCBITaxon:10090 MGI_allele:1857622 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:18026104 IMP NCBITaxon:10090 MGI:109275 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0010629 negative regulation of gene expression PMID:18026104 IMP NCBITaxon:10090 MGI:109275 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0030852 regulation of granulocyte differentiation PMID:11222375 IMP NCBITaxon:10090 MGI_allele:1857622 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0032526 response to retinoic acid PMID:11222375 IMP NCBITaxon:10090 MGI_allele:1857622 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:15766748 IMP NCBITaxon:10090 MGI:106918|MGI:88071 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:7823919 IMP NCBITaxon:10090 GI:98214|MGI:98215|MGI:98216 UniProtKB:P11416 20100215 PRO:HJD PR:P11416 retinoic acid receptor alpha (mouse) mRARA|Nr1b1|nuclear receptor subfamily 1 group B member 1 (mouse)|RAR-alpha (mouse)|Rara acts_upstream_of_or_within GO:0055012 ventricular cardiac muscle cell differentiation PMID:9428411 IMP NCBITaxon:10090 MGI_allele:1857622 UniProtKB:P11416 20100215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI_ref:3053708|PMID:1655807 IDA NCBITaxon:10090 MGI:97856 20140522 MGI:MGI has_direct_input(MGI:97587) PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0003677 DNA binding PMID:14980219 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0003677 DNA binding PMID:15528198 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0003700 DNA-binding transcription factor activity PMID:15528198 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0003700 DNA-binding transcription factor activity PMID:8152920 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0004879 nuclear receptor activity PMID:15528198 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0004879 nuclear receptor activity PMID:15322135 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0005515 protein binding PR:Q64127 PMID:8978696 IPI NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0005515 protein binding PR:Q8CBD1 PMID:10531331 IPI NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 enables GO:0043565 sequence-specific DNA binding PMID:17928865 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 located_in GO:0005634 nucleus CHEBI:15367 PMID:12079996 IDA NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 located_in GO:0005737 cytoplasm PMID:12079996 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 located_in GO:0030425 dendrite MGI_ref:3803427|PMID:18495661 IDA NCBITaxon:10090 MGI:97856 20091202 MGI:MGI part_of(EMAP:12574),part_of(CL:0000540) PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 located_in GO:0043025 neuronal cell body MGI_ref:3803427|PMID:18495661 IDA NCBITaxon:10090 MGI:97856 20091202 MGI:MGI part_of(EMAP:12574),part_of(CL:0000540) PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:8152920 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12079996 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12101409 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:11641275 EXP NCBITaxon:10090 UniProtKB:P11416-1 20091215 PRO:HJD PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse) mRARA/iso:1|mRARalpha1 acts_upstream_of_or_within GO:0045947 negative regulation of translational initiation MGI_ref:3803427|PMID:18495661 IDA NCBITaxon:10090 MGI:97856 20091202 MGI:MGI PR:P12643-1 bone morphogenetic protein 2 isoform 1 (human) hBMP2/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:P12643-1 bone morphogenetic protein 2 isoform 1 (human) hBMP2/iso:1 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:2315314 IDA NCBITaxon:9606 UniProtKB:P12643-1 20080301 PRO:CNA PR:P12644-1 bone morphogenetic protein 4 isoform 1 (human) hBMP4/iso:1 located_in GO:0005622 intracellular anatomical structure PMID:12805376 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:P12644-1 bone morphogenetic protein 4 isoform 1 (human) hBMP4/iso:1 acts_upstream_of_or_within GO:0007498 mesoderm development PMID:9804553 IDA NCBITaxon:9606 UniProtKB:P12644-1 20080301 PRO:CNA PR:P13569-3 cystic fibrosis transmembrane conductance regulator isoform 3 (human) hCFTR/iso:3 associated_with_disease_progression DOID:1485 cystic fibrosis PMID:12913074 EXP NCBITaxon:9606 UniProtKB:P13569-3 20180511 PRO:CNA PR:P13987-1 CD59 glycoprotein isoform 1 (human) hCD59/iso:1 has_role CHEBI:59163 biomarker PMID:18829504 EXP NCBITaxon:9606 UniProtKB:P13987-1 20100525 SALO:AJ PR:P14719-1 interleukin-1 receptor-like 1 isoform A (mouse) interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)|interleukin-1 receptor-like 1 isoform ST2L (mouse)|mIL1RL1/iso:A enables GO:0002113 interleukin-33 binding PR:Q66H70 MGI_ref:3713172|PMID:17492053 IPI NCBITaxon:10090 MGI:98427 20140425 MGI:MGI PR:P14719-1 interleukin-1 receptor-like 1 isoform A (mouse) interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)|interleukin-1 receptor-like 1 isoform ST2L (mouse)|mIL1RL1/iso:A enables GO:0002113 interleukin-33 binding PR:Q8BVZ5 MGI_ref:3723275|PMID:17623648 IPI NCBITaxon:10090 MGI:98427 20080228 MGI:MGI PR:P14719-1 interleukin-1 receptor-like 1 isoform A (mouse) interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)|interleukin-1 receptor-like 1 isoform ST2L (mouse)|mIL1RL1/iso:A enables GO:0002114 interleukin-33 receptor activity PR:Q8BVZ5 MGI_ref:3723275|PMID:17623648 IPI NCBITaxon:10090 MGI:98427 20080228 MGI:MGI PR:P14719-1 interleukin-1 receptor-like 1 isoform A (mouse) interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)|interleukin-1 receptor-like 1 isoform ST2L (mouse)|mIL1RL1/iso:A located_in GO:0009897 external side of plasma membrane MGI_ref:65300|PMID:8131748 IDA NCBITaxon:10090 MGI:98427 20140423 MGI:MGI occurs_in(CL:0000235) PR:P14719-1 interleukin-1 receptor-like 1 isoform A (mouse) interleukin-1 receptor-like 1 isoform Membrane-bound (mouse)|interleukin-1 receptor-like 1 isoform ST2L (mouse)|mIL1RL1/iso:A located_in GO:0016020 membrane MGI_ref:71218|PMID:7883081 IDA NCBITaxon:10090 MGI:98427 20140424 MGI:MGI occurs_in(CL:0000097) PR:P14719-2 interleukin-1 receptor-like 1 isoform B (mouse) interleukin-1 receptor-like 1 isoform Soluble (mouse)|interleukin-1 receptor-like 1 isoform ST2 (mouse)|mIL1RL1/iso:B enables GO:0002113 interleukin-33 binding PR:Q8BVZ5 MGI_ref:3723275|PMID:17623648 IPI NCBITaxon:10090 MGI:98427 20111207 MGI:MGI PR:P14719-2 interleukin-1 receptor-like 1 isoform B (mouse) interleukin-1 receptor-like 1 isoform Soluble (mouse)|interleukin-1 receptor-like 1 isoform ST2 (mouse)|mIL1RL1/iso:B located_in GO:0031012 extracellular matrix MGI_ref:71218|PMID:7883081 IDA NCBITaxon:10090 MGI:98427 20140424 MGI:MGI occurs_in(EMAP:12760) PR:P14719-2 interleukin-1 receptor-like 1 isoform B (mouse) interleukin-1 receptor-like 1 isoform Soluble (mouse)|interleukin-1 receptor-like 1 isoform ST2 (mouse)|mIL1RL1/iso:B acts_upstream_of_or_within GO:0043124 negative regulation of canonical NF-kappaB signal transduction MGI_ref:3723275|PMID:17623648 IDA NCBITaxon:10090 MGI:98427 20080227 MGI:MGI PR:P15209-1 BDNF/NT-3 growth factors receptor isoform 1 (mouse) GP145-TRKB (mouse)|L3 (mouse)|mNTRK2/iso:1|TRKB-FL|TrkBTK+ (mouse) located_in GO:0045211 postsynaptic membrane MGI_ref:1349225|PMID:10595510 IDA NCBITaxon:10090 MGI:97384 20130301 MGI:MGI PR:P15209-1 BDNF/NT-3 growth factors receptor isoform 1 (mouse) GP145-TRKB (mouse)|L3 (mouse)|mNTRK2/iso:1|TRKB-FL|TrkBTK+ (mouse) acts_upstream_of_or_within GO:0007528 neuromuscular junction development MGI_ref:1349225|PMID:10595510 IMP NCBITaxon:10090 MGI_allele:1857814 MGI:97384 20130301 MGI:MGI PR:P15209-2 BDNF/NT-3 growth factors receptor isoform 2 (mouse) GP95-TRKB (mouse)|mNTRK2/iso:2|TRKB-T1 (mouse)|TrkBTK- (mouse) located_in GO:0045211 postsynaptic membrane MGI_ref:1349225|PMID:10595510 IDA NCBITaxon:10090 MGI:97384 20130301 MGI:MGI PR:P15379-3 CD44 antigen isoform 12 (mouse) M1|mCD44/iso:12 enables GO:0005540 hyaluronic acid binding MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20080107 MGI:MGI PR:P15379-3 CD44 antigen isoform 12 (mouse) M1|mCD44/iso:12 located_in GO:0009986 cell surface MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20080107 MGI:MGI PR:P15379-3 CD44 antigen isoform 12 (mouse) M1|mCD44/iso:12 acts_upstream_of_or_within GO:0007155 cell adhesion MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20080107 MGI:MGI PR:P15379-4 CD44 antigen isoform 4 (mouse) M2|mCD44/iso:4 acts_upstream_of_or_within GO:0007155 cell adhesion MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20120215 MGI:MGI PR:P15379-5 CD44 antigen isoform 6 (mouse) M3|mCD44/iso:6 enables GO:0005540 hyaluronic acid binding MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20111207 MGI:MGI PR:P15379-5 CD44 antigen isoform 6 (mouse) M3|mCD44/iso:6 located_in GO:0009986 cell surface MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20120215 MGI:MGI PR:P15379-5 CD44 antigen isoform 6 (mouse) M3|mCD44/iso:6 acts_upstream_of_or_within GO:0007155 cell adhesion MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20120215 MGI:MGI PR:P15379-6 CD44 antigen isoform 7 (mouse) M4|mCD44/iso:7 enables GO:0005540 hyaluronic acid binding MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20111207 MGI:MGI PR:P15379-6 CD44 antigen isoform 7 (mouse) M4|mCD44/iso:7 located_in GO:0009986 cell surface MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20120215 MGI:MGI PR:P15379-6 CD44 antigen isoform 7 (mouse) M4|mCD44/iso:7 acts_upstream_of_or_within GO:0007155 cell adhesion MGI_ref:893774|PMID:1469058 IDA NCBITaxon:10090 MGI:88338 20120215 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity MGI_ref:75839|PMID:7641815 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity MGI_ref:84206|PMID:8787759 IMP NCBITaxon:10090 MGI_allele:2388614 MGI:95705 20080811 MGI:MGI occurs_in(MA:0000792),occurs_in(CL:0000150) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0008092 cytoskeletal protein binding MGI_ref:65229|PMID:8134355 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0008092 cytoskeletal protein binding MGI_ref:75839|PMID:7641815 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0008378 galactosyltransferase activity MGI_ref:65229|PMID:8134355 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 enables GO:0008378 galactosyltransferase activity MGI_ref:68417|PMID:8089187 IDA NCBITaxon:10090 MGI:95705 20080807 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 located_in GO:0009986 cell surface MGI_ref:65229|PMID:8134355 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 located_in GO:0009986 cell surface MGI_ref:68417|PMID:8089187 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI part_of(CL:0000019) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 located_in GO:0009986 cell surface MGI_ref:75839|PMID:7641815 IDA NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 located_in GO:0009986 cell surface MGI_ref:84206|PMID:8787759 IMP NCBITaxon:10090 MGI_allele:2388614 MGI:95705 20080811 MGI:MGI part_of(MA:0000792),part_of(CL:0000150) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation MGI_ref:75839|PMID:7641815 IGI NCBITaxon:10090 MGI:95290|MGI:95294 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0030198 extracellular matrix organization MGI_ref:84206|PMID:8787759 IMP NCBITaxon:10090 MGI_allele:2388614 MGI:95705 20080811 MGI:MGI occurs_in(MA:0000792),has_participant(CL:0000150) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0030879 mammary gland development MGI_ref:2178150|PMID:11900463 IMP NCBITaxon:10090 MGI_allele:2450889 MGI:95705 20080811 MGI:MGI results_in_development_of(MA:0000791) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0042127 regulation of cell population proliferation MGI_ref:75839|PMID:7641815 IMP NCBITaxon:10090 MGI:95705 20080811 MGI:MGI PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0048754 branching morphogenesis of an epithelial tube MGI_ref:2178150|PMID:11900463 IMP NCBITaxon:10090 MGI_allele:2450889 MGI:95705 20080811 MGI:MGI has_participant(MA:0000791) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0048754 branching morphogenesis of an epithelial tube MGI_ref:3052392|PMID:15282149 IMP NCBITaxon:10090 MGI_allele:2178779 MGI:95705 20080811 MGI:MGI has_participant(MA:0000791) PR:P15535-1 beta-1,4-galactosyltransferase 1 isoform 1 (mouse) mB4GALT1/iso:1 acts_upstream_of_or_within GO:0060058 positive regulation of apoptotic process involved in mammary gland involution MGI_ref:3052392|PMID:15282149 IMP NCBITaxon:10090 MGI_allele:2178779 MGI:95705 20080811 MGI:MGI regulates_o_occurs_in(MA:0000791) PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human) hKCNA2/iso:1 located_in GO:0009986 cell surface PMID:15215309 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human) hKCNA2/iso:1 part_of GO:0008076 voltage-gated potassium channel complex PMID:2251283 TAS NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human) hKCNA2/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:1715584 IDA NCBITaxon:9606 UniProtKB:P16389-1 20080601 PRO:CNA PR:P17125-1 transforming growth factor beta-3 isoform 1 (mouse) mTGFB3/iso:1 acts_upstream_of_or_within GO:0030879 mammary gland development PMID:1821856 IDA NCBITaxon:10090 UniProtKB:P17125-1 20080301 PRO:CNA PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI_ref:77668|PMID:8524811 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 enables GO:0003712 transcription coregulator activity MGI_ref:77668|PMID:8524811 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 enables GO:0008301 DNA binding, bending MGI_ref:4946306|PMID:21436399 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 enables GO:0043565 sequence-specific DNA binding MGI_ref:77668|PMID:8524811 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 located_in GO:0005634 nucleus MGI_ref:77668|PMID:8524811 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-1 erythroid transcription factor isoform 1 (mouse) mGATA-1|mGATA1/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:77668|PMID:8524811 IDA NCBITaxon:10090 MGI:95661 20110506 MGI:MGI PR:P17679-2 erythroid transcription factor isoform 2 (mouse) mGATA-1s|mGATA1/iso:2 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8524811 EXP NCBITaxon:10090 UniProtKB:P17679-2 20110506 PRO:HJD PR:P17679-2 erythroid transcription factor isoform 2 (mouse) mGATA-1s|mGATA1/iso:2 enables GO:0003712 transcription coregulator activity PMID:8524811 EXP NCBITaxon:10090 UniProtKB:P17679-2 20110506 PRO:HJD PR:P17679-2 erythroid transcription factor isoform 2 (mouse) mGATA-1s|mGATA1/iso:2 enables GO:0043565 sequence-specific DNA binding PMID:8524811 EXP NCBITaxon:10090 UniProtKB:P17679-2 20110506 PRO:HJD PR:P17679-2 erythroid transcription factor isoform 2 (mouse) mGATA-1s|mGATA1/iso:2 located_in GO:0005634 nucleus PMID:8524811 EXP NCBITaxon:10090 UniProtKB:P17679-2 20110506 PRO:HJD PR:P17679-2 erythroid transcription factor isoform 2 (mouse) mGATA-1s|mGATA1/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8524811 EXP NCBITaxon:10090 UniProtKB:P17679-2 20110506 PRO:HJD PR:P17710-1 hexokinase-1 isoform 1 (mouse) HK1-SA (mouse)|mHK1/iso:1 enables GO:0004340 glucokinase activity MGI_ref:3814792|PMID:18509164 IDA NCBITaxon:10090 MGI:96103 20131213 MGI:MGI occurs_in(CL:0000019) PR:P17710-1 hexokinase-1 isoform 1 (mouse) HK1-SA (mouse)|mHK1/iso:1 located_in GO:0005739 mitochondrion MGI_ref:2445910|PMID:12420306 IDA NCBITaxon:10090 MGI:96103 20101223 MGI:MGI PR:P17710-1 hexokinase-1 isoform 1 (mouse) HK1-SA (mouse)|mHK1/iso:1 located_in GO:0005929 cilium MGI_ref:3654822|PMID:16687649 IDA NCBITaxon:10090 MGI:96103 20131213 MGI:MGI part_of(CL:0000019) PR:P17710-1 hexokinase-1 isoform 1 (mouse) HK1-SA (mouse)|mHK1/iso:1 located_in GO:0097228 sperm principal piece MGI_ref:4443253|PMID:19889946 IDA NCBITaxon:10090 MGI:96103 20131213 MGI:MGI part_of(CL:0000019) PR:P17710-1 hexokinase-1 isoform 1 (mouse) HK1-SA (mouse)|mHK1/iso:1 acts_upstream_of_or_within GO:0061621 canonical glycolysis MGI_ref:3814792|PMID:18509164 IC NCBITaxon:10090 GO:0004340 MGI:96103 20140520 MGI:MGI occurs_in(CL:0000019) PR:P18075-1 bone morphogenetic protein 7 isoform 1 (human) hBMP7/iso:1 enables GO:0005515 protein binding PMID:12805376 IPI NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:P18075-1 bone morphogenetic protein 7 isoform 1 (human) hBMP7/iso:1 located_in GO:0005794 Golgi apparatus PMID:12805376 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:P18075-1 bone morphogenetic protein 7 isoform 1 (human) hBMP7/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:2357959 IDA NCBITaxon:9606 UniProtKB:P18075-1 20080301 PRO:CNA PR:P18510-2 interleukin-1 receptor antagonist protein isoform 2 (human) hIL1RN/iso:2|interleukin-1 receptor antagonist protein isoform icIL-1ra (human) located_in GO:0005615 extracellular space PMID:16564702 IDA NCBITaxon:9606 UniProtKB:P18510-2 20080922 PRO:CNA Note=In response to P2RX7 receptor or ATP stimulation PR:P18510-2 interleukin-1 receptor antagonist protein isoform 2 (human) hIL1RN/iso:2|interleukin-1 receptor antagonist protein isoform icIL-1ra (human) located_in GO:0005622 intracellular anatomical structure PMID:1827201 IDA NCBITaxon:9606 UniProtKB:P18510-2 20080922 PRO:CNA PR:P18510-3 interleukin-1 receptor antagonist protein isoform 3 (human) hIL1RN/iso:3|interleukin-1 receptor antagonist protein isoform icIL-1ra type II (human) located_in GO:0005622 intracellular anatomical structure PMID:7629520 IDA NCBITaxon:9606 UniProtKB:P18510-3 20080922 PRO:CNA PR:P18510-4 interleukin-1 receptor antagonist protein isoform 4 (human) hIL1RN/iso:4 located_in GO:0005622 intracellular anatomical structure PMID:12671514 IC NCBITaxon:9606 PMID:12671514 UniProtKB:P18510-4 20080922 PRO:CNA PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 enables GO:0000064 L-ornithine transmembrane transporter activity MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20080104 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 enables GO:0015189 L-lysine transmembrane transporter activity MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20080104 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 enables GO:0097626 low-affinity L-arginine transmembrane transporter activity MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20140829 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 enables GO:0097626 low-affinity L-arginine transmembrane transporter activity MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140829 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 acts_upstream_of_or_within GO:0097638 L-arginine import across plasma membrane MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 acts_upstream_of_or_within GO:0097638 L-arginine import across plasma membrane MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 acts_upstream_of_or_within GO:0097639 L-lysine import across plasma membrane MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18581-1 cationic amino acid transporter 2 isoform 1 (mouse) cationic amino acid transporter 2 isoform Alpha (mouse)|mSLC7A2/iso:1 acts_upstream_of_or_within GO:1903352 L-ornithine transmembrane transport MGI_ref:66868|PMID:8385111 IDA NCBITaxon:10090 MGI:99828 20140829 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 enables GO:0005289 high-affinity L-arginine transmembrane transporter activity MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140808 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 enables GO:0005292 high-affinity lysine transmembrane transporter activity MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140808 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 enables GO:0097627 high-affinity L-ornithine transmembrane transporter activity MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140829 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 acts_upstream_of_or_within GO:0097638 L-arginine import across plasma membrane MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 acts_upstream_of_or_within GO:0097639 L-lysine import across plasma membrane MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18581-2 cationic amino acid transporter 2 isoform 2 (mouse) cationic amino acid transporter 2 isoform Beta (mouse)|mSLC7A2/iso:2 acts_upstream_of_or_within GO:0097640 L-ornithine import across plasma membrane MGI_ref:67167|PMID:8195186 IDA NCBITaxon:10090 MGI:99828 20140912 MGI:MGI PR:P18761-1 carbonic anhydrase 6 isoform 1 (mouse) mCA6/iso:1 located_in GO:0005615 extracellular space PMID:9858573 EXP NCBITaxon:10090 UniProtKB:P18761-1 20110617 PRO:HJD PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI_ref:3053708|PMID:1655807 IDA NCBITaxon:10090 MGI:97858 20140522 MGI:MGI has_direct_input(MGI:97857) PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) located_in GO:0005634 nucleus MGI_ref:3053708|PMID:1655807 IDA NCBITaxon:10090 MGI:97858 20140522 MGI:MGI PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) acts_upstream_of_or_within GO:0043010 camera-type eye development MGI_ref:1096258|PMID:9376317 IGI NCBITaxon:10090 MGI:98214 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000261) PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:77094|PMID:2157970 IDA NCBITaxon:10090 MGI:97858 20140521 MGI:MGI PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) acts_upstream_of_or_within GO:0060348 bone development MGI_ref:1096258|PMID:9376317 IGI NCBITaxon:10090 MGI:97856 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000311) PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) acts_upstream_of_or_within GO:0060534 trachea cartilage development MGI_ref:1096258|PMID:9376317 IMP NCBITaxon:10090 MGI_allele:2445724 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0001762) PR:P18911-1 retinoic acid receptor gamma isoform 1 (mouse) mRARG/iso:1|RAR-gamma-1 (mouse)|RAR-gamma-A (mouse)|retinoic acid receptor gamma isoform A (mouse) acts_upstream_of_or_within GO:0071300 cellular response to retinoic acid MGI_ref:77094|PMID:2157970 IDA NCBITaxon:10090 MGI:97858 20140521 MGI:MGI PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0003406 retinal pigment epithelium development MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97857 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P22605-3) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97857 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P22605-3) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0043010 camera-type eye development MGI_ref:1096258|PMID:9376317 IGI NCBITaxon:10090 MGI:98214 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000261) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97857 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P22605-3) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:77094|PMID:2157970 IDA NCBITaxon:10090 MGI:97858 20140521 MGI:MGI PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0060041 retina development in camera-type eye MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97857 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000276),in_absence_of(PR:P22605-3) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0060348 bone development MGI_ref:1096258|PMID:9376317 IGI NCBITaxon:10090 MGI:97856 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0000311) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0060534 trachea cartilage development MGI_ref:1096258|PMID:9376317 IMP NCBITaxon:10090 MGI_allele:1932114|MGI_allele:2445724 MGI:97858 20140523 MGI:MGI results_in_development_of(MA:0001762),in_absence_of(PR:P18911-1) PR:P18911-2 retinoic acid receptor gamma isoform 2 (mouse) mRARG/iso:2|RAR-gamma-2 (mouse)|RAR-gamma-B (mouse)|retinoic acid receptor gamma isoform B (mouse) acts_upstream_of_or_within GO:0071300 cellular response to retinoic acid MGI_ref:77094|PMID:2157970 IDA NCBITaxon:10090 MGI:97858 20140521 MGI:MGI PR:P19256 lymphocyte function-associated antigen 3 (human) Ag3 (human)|CD58|hCD58|LFA3|surface glycoprotein LFA-3 (human) enables GO:0005515 protein binding PR:000036596 PMID:7544493|PMID:7688025 IPI NCBITaxon:9606 UniProtKB:P19256 20080922 PRO:CNA PR:P19883-1 follistatin isoform 1 (human) follistatin isoform FS-315 (human)|follistatin isoform FS315 (human)|hFST/iso:1 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:9828086 TAS NCBITaxon:9606 UniProtKB:P19883-1 20080301 PRO:CNA PR:P20067 DNA-binding protein inhibitor ID-1 (mouse) Id|Id-1|Id1|Idb1|inhibitor of differentiation 1 (mouse)|inhibitor of DNA binding 1 (mouse)|mID1 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:12498716 IMP NCBITaxon:10090 UniProtKB:P20067 20080301 PRO:CNA PR:P20067 DNA-binding protein inhibitor ID-1 (mouse) Id|Id-1|Id1|Idb1|inhibitor of differentiation 1 (mouse)|inhibitor of DNA binding 1 (mouse)|mID1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:15820682 TAS NCBITaxon:10090 UniProtKB:P20067 20080301 PRO:CNA PR:P20263-1 POU domain, class 5, transcription factor 1 isoform 1 (mouse) mPOU5F1/iso:1 acts_upstream_of_or_within GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5490149|PMID:23495099 IMP NCBITaxon:10090 MGI:101893 20140910 MGI:MGI PR:P20334-1 tumor necrosis factor receptor superfamily member 9 isoform 1 (mouse) 4-1BB|CD137|mTNFRSF9/iso:1 located_in GO:0009897 external side of plasma membrane MGI_ref:3807131|PMID:18640726 IDA NCBITaxon:10090 MGI:1101059 20121217 MGI:MGI part_of(CL:0000624)|part_of(CL:0000625) PR:P20722-1 bone morphogenetic protein 6 isoform 1 (mouse) mBMP6/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:8089189 IDA NCBITaxon:10090 UniProtKB:P20722-1 20080301 PRO:CNA PR:P20722-1 bone morphogenetic protein 6 isoform 1 (mouse) mBMP6/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8089189 IDA NCBITaxon:10090 UniProtKB:P20722-1 20080301 PRO:CNA PR:P20749 B-cell lymphoma 3 protein (human) BCL-3 (human)|BCL3|BCL4|D19S37|hBCL3|proto-oncogene BCL3 (human) located_in GO:0005634 nucleus PMID:16280327 EXP NCBITaxon:9606 UniProtKB:P20749 20100520 PRO:CNA PR:P20749 B-cell lymphoma 3 protein (human) BCL-3 (human)|BCL3|BCL4|D19S37|hBCL3|proto-oncogene BCL3 (human) part_of GO:0032996 Bcl3-Bcl10 complex PR:000025714 PMID:16280327 IPI NCBITaxon:9606 UniProtKB:P20749 20100520 PRO:CNA PR:P21274-1 bone morphogenetic protein 2 isoform 1 (mouse) mBMP2/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P21274-1 20080301 PRO:CNA PR:P21275 bone morphogenetic protein 4 (mouse) BMP-2B (mouse)|Bmp-4|BMP-4 (mouse)|Bmp4|bone morphogenetic protein 2B (mouse)|Dvr-4|mBMP4 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:14654219|PMID:15936012 IDA NCBITaxon:10090 UniProtKB:P21275 20080301 PRO:CNA PR:P21275 bone morphogenetic protein 4 (mouse) BMP-2B (mouse)|Bmp-4|BMP-4 (mouse)|Bmp4|bone morphogenetic protein 2B (mouse)|Dvr-4|mBMP4 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P21275 20080301 PRO:CNA PR:P22001-1 potassium voltage-gated channel subfamily A member 3 isoform 1 (human) hKCNA3/iso:1 enables GO:0005251 delayed rectifier potassium channel activity PMID:1986382 IDA NCBITaxon:9606 UniProtKB:P22001-1 20080601 PRO:CNA PR:P22001-1 potassium voltage-gated channel subfamily A member 3 isoform 1 (human) hKCNA3/iso:1 located_in GO:0005743 mitochondrial inner membrane PMID:15632141 IDA NCBITaxon:9606 UniProtKB:P22001-1 20080601 PRO:CNA PR:P22001-1 potassium voltage-gated channel subfamily A member 3 isoform 1 (human) hKCNA3/iso:1 located_in GO:0005886 plasma membrane PMID:15632141 IDA NCBITaxon:9606 UniProtKB:P22001-1 20080601 PRO:CNA PR:P22004-1 bone morphogenetic protein 6 isoform 1 (human) hBMP6/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:12702725 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:P22004-1 bone morphogenetic protein 6 isoform 1 (human) hBMP6/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:12702725 IDA NCBITaxon:9606 UniProtKB:P22004-1 20080301 PRO:CNA PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse) mIL6R/iso:1 enables GO:0004915 interleukin-6 receptor activity MGI_ref:50330|PMID:1312474 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse) mIL6R/iso:1 enables GO:0019981 interleukin-6 binding MGI_ref:50330|PMID:1312474 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse) mIL6R/iso:1 located_in GO:0009986 cell surface MGI_ref:50330|PMID:1312474 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse) mIL6R/iso:1 acts_upstream_of_or_within GO:0070102 interleukin-6-mediated signaling pathway MGI_ref:50330|PMID:1312474 IDA NCBITaxon:10090 UniProtKB:P22272-1 20090309 PRO:HJD PR:P22366-2 myeloid differentiation primary response protein MyD88 isoform 2 (mouse) mMYD88/iso:2 acts_upstream_of_or_within GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665 EXP NCBITaxon:10090 UniProtKB:P22366-2 20140514 PRO:CNA PR:P22460-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (human) hKCNA5/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:1986382 IDA NCBITaxon:9606 UniProtKB:P22460-1 20080601 PRO:CNA PR:P22462-1 potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat) rKCNC2/iso:KV3.2B contributes_to enables GO:0015271 outward rectifier potassium channel activity PMID:1879548 IDA NCBITaxon:10116 UniProtKB:P22462-1 20080601 PRO:CNA PR:P22462-3 potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat) rKCNC2/iso:KSHIIIA.1 contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:10414303|PMID:11506885 IDA NCBITaxon:10116 UniProtKB:P22462-3 20080601 PRO:CNA Note=Correct species assignment not stated, but can be discerned from sequence shown in PMID:10414303 PR:P22561-1 Wilms tumor protein homolog isoform 1 (mouse) mWT1/iso:1 enables GO:0003723 RNA binding MGI_ref:3032819|PMID:14681305 IDA NCBITaxon:10090 MGI:98968 20090414 MGI:MGI PR:P22561-1 Wilms tumor protein homolog isoform 1 (mouse) mWT1/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3032819|PMID:14681305 IDA NCBITaxon:10090 MGI:98968 20090410 MGI:MGI PR:P22561-1 Wilms tumor protein homolog isoform 1 (mouse) mWT1/iso:1 acts_upstream_of_or_within GO:0009888 tissue development MGI_ref:3574744|PMID:15716344 IMP NCBITaxon:10090 MGI_allele:2183640 MGI:98968 20080811 MGI:MGI results_in_development_of(EMAP:4349) PR:P22561-2 Wilms tumor protein homolog isoform 2 (mouse) mWT1/iso:2 acts_upstream_of_or_within GO:0043010 camera-type eye development MGI_ref:3574744|PMID:15716344 IMP NCBITaxon:10090 MGI_allele:2183642 MGI:98968 20080902 MGI:MGI results_in_development_of(EMAP:4344) PR:P22561-2 Wilms tumor protein homolog isoform 2 (mouse) mWT1/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3607478|PMID:16264195 IDA NCBITaxon:10090 MGI:98968 20080807 MGI:MGI has_regulation_target(MGI:MGI:97384) PR:P22561-4 Wilms tumor protein homolog isoform 4 (mouse) mWT1/iso:4 enables GO:0003723 RNA binding MGI_ref:3032819|PMID:14681305 IDA NCBITaxon:10090 MGI:98968 20120112 MGI:MGI PR:P22561-4 Wilms tumor protein homolog isoform 4 (mouse) mWT1/iso:4 located_in GO:0005737 cytoplasm MGI_ref:3032819|PMID:14681305 IDA NCBITaxon:10090 MGI:98968 20120112 MGI:MGI PR:P22561-4 Wilms tumor protein homolog isoform 4 (mouse) mWT1/iso:4 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3607478|PMID:16264195 IDA NCBITaxon:10090 MGI:98968 20120112 MGI:MGI has_regulation_target(MGI:MGI:97384) PR:P22605-1 retinoic acid receptor beta isoform 1 (mouse) mRARB/iso:1|RARB isoform Beta-3 (mouse) enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI_ref:70385|PMID:7831303 IDA NCBITaxon:10090 MGI:98215 20140630 MGI:MGI PR:P22605-1 retinoic acid receptor beta isoform 1 (mouse) mRARB/iso:1|RARB isoform Beta-3 (mouse) enables GO:0042803 protein homodimerization activity MGI_ref:70385|PMID:7831303 IDA NCBITaxon:10090 MGI:98215 20140630 MGI:MGI PR:P22605-3 retinoic acid receptor beta isoform 3 (mouse) mRARB/iso:3|RARB isoform Beta-2 (mouse) enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI_ref:3053708|PMID:1655807 IDA NCBITaxon:10090 MGI:97857 20140522 MGI:MGI has_direct_input(MGI:97857) PR:P22605-3 retinoic acid receptor beta isoform 3 (mouse) mRARB/iso:3|RARB isoform Beta-2 (mouse) acts_upstream_of_or_within GO:0003406 retinal pigment epithelium development MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97858 MGI:97857 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P18911-2) PR:P22605-3 retinoic acid receptor beta isoform 3 (mouse) mRARB/iso:3|RARB isoform Beta-2 (mouse) acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97858 MGI:97857 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P18911-2) PR:P22605-3 retinoic acid receptor beta isoform 3 (mouse) mRARB/iso:3|RARB isoform Beta-2 (mouse) acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97858 MGI:97857 20140523 MGI:MGI results_in_development_of(MA:0000279),in_absence_of(PR:P18911-2) PR:P22605-3 retinoic acid receptor beta isoform 3 (mouse) mRARB/iso:3|RARB isoform Beta-2 (mouse) acts_upstream_of_or_within GO:0060041 retina development in camera-type eye MGI_ref:81656|PMID:8681798 IGI NCBITaxon:10090 MGI:97858 MGI:97857 20140523 MGI:MGI results_in_development_of(MA:0000276),in_absence_of(PR:P18911-2) PR:P23359 bone morphogenetic protein 7 (mouse) Bmp-7|BMP-7 (mouse)|Bmp7|mBMP7|OP-1 (mouse)|Op1|osteogenic protein 1 (mouse) acts_upstream_of_or_within GO:0007435 salivary gland morphogenesis PMID:11731698 IDA NCBITaxon:10090 UniProtKB:P23359 20080301 PRO:CNA PR:P23359 bone morphogenetic protein 7 (mouse) Bmp-7|BMP-7 (mouse)|Bmp7|mBMP7|OP-1 (mouse)|Op1|osteogenic protein 1 (mouse) acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:7590254 IDA NCBITaxon:10090 UniProtKB:P23359 20080301 PRO:CNA PR:P23359 bone morphogenetic protein 7 (mouse) Bmp-7|BMP-7 (mouse)|Bmp7|mBMP7|OP-1 (mouse)|Op1|osteogenic protein 1 (mouse) acts_upstream_of_or_within GO:0035239 tube morphogenesis PMID:15831470 IDA NCBITaxon:10090 UniProtKB:P23359 20080301 PRO:CNA PR:P23359 bone morphogenetic protein 7 (mouse) Bmp-7|BMP-7 (mouse)|Bmp7|mBMP7|OP-1 (mouse)|Op1|osteogenic protein 1 (mouse) acts_upstream_of_or_within GO:0042475 odontogenesis of dentin-containing tooth PMID:15525533 IDA NCBITaxon:10090 UniProtKB:P23359 20080301 PRO:CNA PR:P23359 bone morphogenetic protein 7 (mouse) Bmp-7|BMP-7 (mouse)|Bmp7|mBMP7|OP-1 (mouse)|Op1|osteogenic protein 1 (mouse) acts_upstream_of_or_within GO:0048754 branching morphogenesis of an epithelial tube PMID:15831470 IDA NCBITaxon:10090 UniProtKB:P23359 20080301 PRO:CNA PR:P23359-1 bone morphogenetic protein 7 isoform 1 (mouse) mBMP7/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14623234 IDA NCBITaxon:10090 UniProtKB:P23359-1 20080301 PRO:CNA PR:P23443-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (human) hRPS6KB1/iso:Alpha I|ribosomal protein S6 kinase beta-1 isoform p80-S6K 1 (human) acts_upstream_of_or_within GO:0007165 signal transduction PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-1 20080301 PRO:CNA PR:P23443-1 ribosomal protein S6 kinase beta-1 isoform Alpha I (human) hRPS6KB1/iso:Alpha I|ribosomal protein S6 kinase beta-1 isoform p80-S6K 1 (human) NOT enables GO:0004672 protein kinase activity PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-1 20080301 PRO:CNA PR:P23443-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (human) hRPS6KB1/iso:Alpha II acts_upstream_of_or_within GO:0007165 signal transduction PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-2 20080301 PRO:CNA PR:P23443-2 ribosomal protein S6 kinase beta-1 isoform Alpha II (human) hRPS6KB1/iso:Alpha II NOT enables GO:0004672 protein kinase activity PMID:1922062 IDA NCBITaxon:9606 UniProtKB:P23443-2 20080301 PRO:CNA PR:P23708-2 nuclear transcription factor Y subunit alpha isoform 2 (mouse) mNFYA short|mNFYA/iso:2|nuclear transcription factor Y subunit alpha isoform short (mouse) acts_upstream_of_or_within GO:2000036 regulation of stem cell population maintenance MGI_ref:5474438|PMID:22969033 IDA NCBITaxon:10090 MGI:97316 20131016 MGI:MGI regulates_o_acts_on_population_of(CL:0002322) PR:P23708-2 nuclear transcription factor Y subunit alpha isoform 2 (mouse) mNFYA short|mNFYA/iso:2|nuclear transcription factor Y subunit alpha isoform short (mouse) acts_upstream_of_or_within GO:2000648 positive regulation of stem cell proliferation MGI_ref:5474438|PMID:22969033 IDA NCBITaxon:10090 MGI:97316 20131016 MGI:MGI regulates_o_acts_on_population_of(CL:0002322) PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) enables GO:0005515 protein binding PR:O14641 PMID:20823832 IPI NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) enables GO:0005515 protein binding PR:O43683 PMID:11283619 IPI NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) enables GO:0005515 protein binding PR:O43684 PMID:11283619 IPI NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) enables GO:0005515 protein binding PR:Q13257 BioGRID:BG-302957 IPI NCBITaxon:9606 UniProtKB:P25054 20130103 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) enables GO:0008017 microtubule binding PMID:11283619 EXP NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) located_in GO:0000776 kinetochore PMID:11283619 EXP NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER Timing=Mitosis (prometaphase, metaphase, NOT prophase). PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) acts_upstream_of_or_within GO:0007059 chromosome segregation PMID:11283619 EXP NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25054 adenomatous polyposis coli protein (human) APC|deleted in polyposis 2.5 (human)|DP2.5|hAPC|protein APC (human) NOT acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:11283619 EXP NCBITaxon:9606 UniProtKB:P25054 20121124 PRO:KER PR:P25085-2 interleukin-1 receptor antagonist protein isoform 2 (mouse) mIL1RN/iso:2 located_in GO:0005615 extracellular space PMID:1524071 IDA NCBITaxon:10090 UniProtKB:P25085-2 20080922 PRO:CNA Note=In response to P2RX7 receptor or ATP stimulation PR:P25122-1 potassium voltage-gated channel subfamily C member 1 isoform Long (rat) Kcnc1 isoform 1 (rat)|potassium voltage-gated channel subfamily C member 1 isoform 1 (rat)|rKCNC1/iso:Long enables GO:0030506 ankyrin binding PR:O70511 PMID:18094255 IPI NCBITaxon:10116 UniProtKB:P25122-1 20100930 PRO:CNA PR:P25122-1 potassium voltage-gated channel subfamily C member 1 isoform Long (rat) Kcnc1 isoform 1 (rat)|potassium voltage-gated channel subfamily C member 1 isoform 1 (rat)|rKCNC1/iso:Long located_in GO:0030424 axon PMID:18094255 IDA NCBITaxon:10116 UniProtKB:P25122-1 20080601 PRO:CNA PR:P25122-2 potassium voltage-gated channel subfamily C member 1 isoform Short (rat) Kcnc1 isoform 2 (rat)|potassium voltage-gated channel subfamily C member 1 isoform 2 (rat)|rKCNC1/iso:Short located_in GO:0032809 neuronal cell body membrane PMID:18094255 IDA NCBITaxon:10116 UniProtKB:P25122-2 20080601 PRO:CNA PR:P25425-10 POU domain, class 2, transcription factor 1 isoform 10 (mouse) mPOU2F1/iso:10|POU domain, class 2, transcription factor 1 isoform OCT-1Z (mouse) enables GO:0003677 DNA binding MGI_ref:3028744|PMID:14729276 IDA NCBITaxon:10090 MGI:101898 20080108 MGI:MGI PR:P25425-10 POU domain, class 2, transcription factor 1 isoform 10 (mouse) mPOU2F1/iso:10|POU domain, class 2, transcription factor 1 isoform OCT-1Z (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3028744|PMID:14729276 IDA NCBITaxon:10090 MGI:101898 20080108 MGI:MGI PR:P25425-2 POU domain, class 2, transcription factor 1 isoform 2 (mouse) mPOU2F1/iso:2|POU domain, class 2, transcription factor 1 isoform OCT-1B (mouse) enables GO:0003677 DNA binding MGI_ref:3028744|PMID:14729276 IDA NCBITaxon:10090 MGI:101898 20111221 MGI:MGI PR:P25425-2 POU domain, class 2, transcription factor 1 isoform 2 (mouse) mPOU2F1/iso:2|POU domain, class 2, transcription factor 1 isoform OCT-1B (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3028744|PMID:14729276 IDA NCBITaxon:10090 MGI:101898 20111221 MGI:MGI PR:P25445-1 tumor necrosis factor receptor superfamily member 6 isoform 1 (human) hFAS/iso:1 enables GO:0005515 protein binding PR:P15311 PMID:14739941 IPI NCBITaxon:9606 UniProtKB:P25445-1 20090717 PRO:CL PR:P25445-1 tumor necrosis factor receptor superfamily member 6 isoform 1 (human) hFAS/iso:1 located_in GO:0005886 plasma membrane PMID:14739941 EXP NCBITaxon:9606 UniProtKB:P25445-1 20090717 PRO:CL PR:P25445-1 tumor necrosis factor receptor superfamily member 6 isoform 1 (human) hFAS/iso:1 acts_upstream_of_or_within GO:0070231 T cell apoptotic process PMID:14739941 EXP NCBITaxon:9606 UniProtKB:P25445-1 20090717 PRO:CL PR:P25976-1 nucleolar transcription factor 1 isoform UBF1 (mouse) mUBTF/iso:UBF1|nucleolar transcription factor 1 isoform Long (mouse) enables GO:0005515 protein binding PR:Q8QZY1 PMID:11592397 IPI NCBITaxon:10090 UniProtKB:P25976-1 20100215 PRO:HJD PR:P25976-1 nucleolar transcription factor 1 isoform UBF1 (mouse) mUBTF/iso:UBF1|nucleolar transcription factor 1 isoform Long (mouse) located_in GO:0005730 nucleolus PMID:11555636|PMID:12878164|PMID:14729462|PMID:15989966|PMID:19103806 IDA NCBITaxon:10090 UniProtKB:P25976-1 20100215 PRO:HJD PR:P25976-1 nucleolar transcription factor 1 isoform UBF1 (mouse) mUBTF/iso:UBF1|nucleolar transcription factor 1 isoform Long (mouse) acts_upstream_of_or_within GO:0000183 rDNA heterochromatin formation MGI_ref:3836497|PMID:19103806 IDA NCBITaxon:10090 UniProtKB:P25976-1 20100215 PRO:HJD PR:P25976-2 nucleolar transcription factor 1 isoform UBF2 (mouse) mUBTF/iso:UBF2|nucleolar transcription factor 1 isoform Short (mouse) located_in GO:0005730 nucleolus MGI_ref:3836497|PMID:19103806 IDA NCBITaxon:10090 UniProtKB:P25976-2 20100215 PRO:HJD PR:P25976-2 nucleolar transcription factor 1 isoform UBF2 (mouse) mUBTF/iso:UBF2|nucleolar transcription factor 1 isoform Short (mouse) acts_upstream_of_or_within GO:0000183 rDNA heterochromatin formation MGI_ref:3836497|PMID:19103806 IMP NCBITaxon:10090 UniProtKB:P25976-2 20100215 PRO:HJD PR:P26449 cell cycle arrest protein BUB3 (yeast) BUB3|OR26.16|yBUB3|YOR026W enables GO:0005515 protein binding PR:000035536 PMID:22521787 IPI NCBITaxon:4932 UniProtKB:P26449 20121121 PRO:KER PR:P26449 cell cycle arrest protein BUB3 (yeast) BUB3|OR26.16|yBUB3|YOR026W located_in GO:0000776 kinetochore PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P26449 20121121 PRO:KER PR:P26449 cell cycle arrest protein BUB3 (yeast) BUB3|OR26.16|yBUB3|YOR026W acts_upstream_of_or_within GO:0006974 DNA damage response PMID:15514023 EXP NCBITaxon:4932 UniProtKB:P26449 20121121 PRO:KER PR:P27038-1 activin receptor type-2A isoform 1 (mouse) mACVR2A/iso:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:8395525 IDA NCBITaxon:10090 UniProtKB:P27038-1 20080301 PRO:CNA PR:P27040-1 activin receptor type-2B isoform ActR-IIB1 (mouse) mACVR2B/iso:ActR-IIB1 located_in GO:0005886 plasma membrane PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-1 20080301 PRO:CNA PR:P27040-1 activin receptor type-2B isoform ActR-IIB1 (mouse) mACVR2B/iso:ActR-IIB1 part_of GO:0048179 activin receptor complex PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-1 20080301 PRO:CNA PR:P27040-3 activin receptor type-2B isoform ActR-IIB3 (mouse) mACVR2B/iso:ActR-IIB3 located_in GO:0005886 plasma membrane PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-3 20080301 PRO:CNA PR:P27040-3 activin receptor type-2B isoform ActR-IIB3 (mouse) mACVR2B/iso:ActR-IIB3 part_of GO:0048179 activin receptor complex PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-3 20080301 PRO:CNA PR:P27040-4 activin receptor type-2B isoform ActR-IIB4 (mouse) mACVR2B/iso:ActR-IIB4 located_in GO:0005886 plasma membrane PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-4 20080301 PRO:CNA PR:P27040-4 activin receptor type-2B isoform ActR-IIB4 (mouse) mACVR2B/iso:ActR-IIB4 part_of GO:0048179 activin receptor complex PMID:1310075 IDA NCBITaxon:10090 UniProtKB:P27040-4 20080301 PRO:CNA PR:P27361-1 mitogen-activated protein kinase 3 isoform 1 (human) hMAPK3/iso:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:7687743 IDA NCBITaxon:9606 UniProtKB:P27361-1 20091115 PRO:CNA PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human) hMAPK1/iso:1 acts_upstream_of_or_within GO:0006935 chemotaxis PMID:10706854 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human) hMAPK1/iso:1 acts_upstream_of_or_within GO:0006950 response to stress PMID:10958679 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human) hMAPK1/iso:1 acts_upstream_of_or_within GO:0007268 chemical synaptic transmission PMID:10706854 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human) hMAPK1/iso:1 NOT enables GO:0004707 MAP kinase activity PMID:10706854 TAS NCBITaxon:9606 UniProtKB:P28482-1 20080301 PRO:CNA PR:P28659 CUGBP Elav-like family member 1 (mouse) 50 kDa nuclear polyadenylated RNA-binding protein (mouse)|brain protein F41 (mouse)|bruno-like protein 2 (mouse)|Brunol2|CELF-1 (mouse)|Celf1|CUG triplet repeat RNA-binding protein 1 (mouse)|CUG-BP- and ETR-3-like factor 1 (mouse)|CUG-BP1 (mouse)|Cugbp|Cugbp1|deadenylation factor CUG-BP (mouse)|deadenylation factor EDEN-BP (mouse)|EDEN-BP homolog (mouse)|embryo deadenylation element-binding protein homolog (mouse)|mCELF1|RNA-binding protein BRUNOL-2 (mouse) acts_upstream_of_or_within GO:0007286 spermatid development PMID:17130239 IMP NCBITaxon:10090 MGI_allele:3700209 UniProtKB:P28659 20091105 PRO:HJD PR:P28659 CUGBP Elav-like family member 1 (mouse) 50 kDa nuclear polyadenylated RNA-binding protein (mouse)|brain protein F41 (mouse)|bruno-like protein 2 (mouse)|Brunol2|CELF-1 (mouse)|Celf1|CUG triplet repeat RNA-binding protein 1 (mouse)|CUG-BP- and ETR-3-like factor 1 (mouse)|CUG-BP1 (mouse)|Cugbp|Cugbp1|deadenylation factor CUG-BP (mouse)|deadenylation factor EDEN-BP (mouse)|EDEN-BP homolog (mouse)|embryo deadenylation element-binding protein homolog (mouse)|mCELF1|RNA-binding protein BRUNOL-2 (mouse) acts_upstream_of_or_within GO:0040018 positive regulation of multicellular organism growth PMID:17130239 IMP NCBITaxon:10090 MGI_allele:3700209 UniProtKB:P28659 20091105 PRO:HJD PR:P28700-1 retinoic acid receptor RXR-alpha isoform 1 (mouse) mRXRA/iso:1|RXR-alpha1 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:85343|PMID:8954108 IDA NCBITaxon:10090 MGI:98214 20140606 MGI:MGI has_input(CHEBI:50648) PR:P28704-2 retinoic acid receptor RXR-beta isoform Short (mouse) mRXRB/iso:Short|RXR-beta-2 (mouse) enables GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding MGI_ref:67933|PMID:2554307 IDA NCBITaxon:10090 MGI:98215 20140529 MGI:MGI PR:P28704-2 retinoic acid receptor RXR-beta isoform Short (mouse) mRXRB/iso:Short|RXR-beta-2 (mouse) enables GO:0004879 nuclear receptor activity MGI_ref:50850|PMID:1312497 IDA NCBITaxon:10090 MGI:98215 20090728 MGI:MGI PR:P28704-2 retinoic acid receptor RXR-beta isoform Short (mouse) mRXRB/iso:Short|RXR-beta-2 (mouse) acts_upstream_of_or_within GO:0048384 retinoic acid receptor signaling pathway MGI_ref:50850|PMID:1312497 IDA NCBITaxon:10090 MGI:98215 20090728 MGI:MGI PR:P28705-1 retinoic acid receptor RXR-gamma isoform 1 (mouse) mRXRG/iso:1|RXR-gamma1 (mouse) enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI_ref:70385|PMID:7831303 IDA NCBITaxon:10090 MGI:98216 20140627 MGI:MGI PR:P28705-1 retinoic acid receptor RXR-gamma isoform 1 (mouse) mRXRG/iso:1|RXR-gamma1 (mouse) acts_upstream_of_or_within GO:0051289 protein homotetramerization MGI_ref:70385|PMID:7831303 IDA NCBITaxon:10090 MGI:98216 20140630 MGI:MGI PR:P28705-1 retinoic acid receptor RXR-gamma isoform 1 (mouse) mRXRG/iso:1|RXR-gamma1 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:60180|PMID:8391126 IDA NCBITaxon:10090 MGI:98216 20140626 MGI:MGI has_input(CHEBI:50648) PR:P28749-1 retinoblastoma-like protein 1 isoform 1 (human) hRBL1/iso:1 enables GO:0005515 protein binding PMID:11884610 IPI NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:P28749-1 retinoblastoma-like protein 1 isoform 1 (human) hRBL1/iso:1 enables GO:0030308 negative regulation of cell growth PMID:11884610 IDA NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:P28749-1 retinoblastoma-like protein 1 isoform 1 (human) hRBL1/iso:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:8319904 IDA NCBITaxon:9606 UniProtKB:P28749-1 20080301 PRO:CNA PR:P29590-1 transcription factor PML isoform 1 (human) hPML/iso:1 enables GO:0005515 protein binding PR:Q13164 PMID:20832753 IPI NCBITaxon:9606 UniProtKB:P29590-1 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P29590-1 transcription factor PML isoform 1 (human) hPML/iso:1 located_in GO:0005634 nucleus PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-1 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-1 transcription factor PML isoform 1 (human) hPML/iso:1 located_in GO:0005737 cytoplasm PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-1 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-1 transcription factor PML isoform 1 (human) hPML/iso:1 located_in GO:0005737 cytoplasm PMID:9885291 IDA NCBITaxon:9606 UniProtKB:P29590-1 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-2 transcription factor PML isoform 2 (human) hPML/iso:2 located_in GO:0005634 nucleus PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-2 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-2 transcription factor PML isoform 2 (human) hPML/iso:2 located_in GO:0005737 cytoplasm PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-2 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-2 transcription factor PML isoform 2 (human) hPML/iso:2 acts_upstream_of_or_within GO:0002230 positive regulation of defense response to virus by host PMID:16873256 IMP NCBITaxon:9606 UniProtKB:P29590-2 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 enables GO:0005515 protein binding PR:P04489 PMID:16501113 IPI NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 enables GO:0005515 protein binding PR:P06400 PMID:9448006 IPI NCBITaxon:9606 UniProtKB:P29590-3 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 enables GO:0005515 protein binding PR:P45481 PMID:10610177 IPI NCBITaxon:9606 UniProtKB:P29590-3 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 enables GO:0005515 protein binding PR:Q64127 PMID:10610177 IPI NCBITaxon:9606 UniProtKB:P29590-3 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 enables GO:0046982 protein heterodimerization activity PMID:7935403 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 located_in GO:0005634 nucleus PMID:9294197 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 located_in GO:0005737 cytoplasm PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 located_in GO:0031965 nuclear membrane PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:9583681 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:9583681 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0030308 negative regulation of cell growth PMID:7935403 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0030308 negative regulation of cell growth PMID:9395203 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0030308 negative regulation of cell growth PMID:9583681 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0030578 PML body organization PMID:10779416 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070216 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-3 transcription factor PML isoform 3 (human) hPML/iso:3 acts_upstream_of_or_within GO:0045930 negative regulation of mitotic cell cycle PMID:9395203 IDA NCBITaxon:9606 UniProtKB:P29590-3 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:P14373 PMID:9570750 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:P23769 PMID:10938104 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:P63073 PMID:11500381 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:P63165 PMID:9885291 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:P63279 PMID:9885291 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:Q03014 PMID:10597310 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0005515 protein binding PR:Q9UER7-1 PMID:10669754 IPI NCBITaxon:9606 UniProtKB:P29590-4 20070928 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0008270 zinc ion binding PMID:7729428 IDA NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 enables GO:0050897 cobalt ion binding PMID:7729428 IDA NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 located_in GO:0016605 PML body PMID:9885291 IDA NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 acts_upstream_of_or_within GO:0002230 positive regulation of defense response to virus by host PMID:16873257 IMP NCBITaxon:9606 UniProtKB:P29590-4 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-4 transcription factor PML isoform 4 (human) hPML/iso:4 acts_upstream_of_or_within GO:0030578 PML body organization PMID:8643677 IDA NCBITaxon:9606 UniProtKB:P29590-4 20070205 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0003713 transcription coactivator activity PMID:11080164 IDA NCBITaxon:9606 UniProtKB:P29590-5 20060112 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0003713 transcription coactivator activity PMID:15626733 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:O15379 PMID:11259576 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070928 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:O96017 PMID:12402044 IPI NCBITaxon:9606 UniProtKB:P29590-5 20060113 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:P04637 PMID:11080164 IPI NCBITaxon:9606 UniProtKB:P29590-5 20060112 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:P06400 PMID:9448006 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:P62913 PMID:15195100 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q00987 PMID:12915590 IPI NCBITaxon:9606 UniProtKB:P29590-5 20071217 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q00987 PMID:12915590 IPI NCBITaxon:9606 UniProtKB:P29590-5 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q05516 PMID:9294197 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q05516 PMID:9294197 IPI NCBITaxon:9606 UniProtKB:P29590-5 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q13547 PMID:11259576 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q92547 PMID:12773567 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070928 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 enables GO:0005515 protein binding PR:Q92769 PMID:11259576 IPI NCBITaxon:9606 UniProtKB:P29590-5 20070928 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 located_in GO:0005730 nucleolus PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 located_in GO:0005737 cytoplasm PMID:16778193 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 located_in GO:0016363 nuclear matrix PMID:11080164 IDA NCBITaxon:9606 UniProtKB:P29590-5 20060112 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 located_in GO:0016605 PML body PMID:9448006 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0006605 protein targeting PMID:11080164 IDA NCBITaxon:9606 UniProtKB:P29590-5 20060112 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0006605 protein targeting PMID:15195100 IMP NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11080164 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:12773567 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070209 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage PMID:12402044 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0030308 negative regulation of cell growth PMID:9448006 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0032938 negative regulation of translation in response to oxidative stress PMID:16915281 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070302 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:9448006 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070202 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29590-5 transcription factor PML isoform 5 (human) hPML/iso:5 acts_upstream_of_or_within GO:0050821 protein stabilization PMID:12773567 IDA NCBITaxon:9606 UniProtKB:P29590-5 20070206 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P29973-1 cGMP-gated cation channel alpha-1 isoform 1 (human) hCNGA1/iso:1 located_in GO:0005886 plasma membrane PMID:7479749 IDA NCBITaxon:9606 UniProtKB:P29973-1 20080601 PRO:CNA PR:P29974 cGMP-gated cation channel alpha-1 (mouse) Cncg|Cncg1|CNG channel alpha-1 (mouse)|CNG-1 (mouse)|CNG1 (mouse)|Cnga1|cyclic nucleotide-gated cation channel 1 (mouse)|cyclic nucleotide-gated channel alpha-1 (mouse)|cyclic nucleotide-gated channel, photoreceptor (mouse)|mCNGA1|rod photoreceptor cGMP-gated channel subunit alpha (mouse) located_in GO:0001750 photoreceptor outer segment PMID:15634774 IDA NCBITaxon:10090 UniProtKB:P29974 20080601 PRO:CNA PR:P30557-1 prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse) mPTGER3/iso:Alpha enables GO:0004957 prostaglandin E receptor activity MGI_ref:64071|PMID:8381413 IDA NCBITaxon:10090 MGI:97795 20090410 MGI:MGI PR:P30728-2 D(3) dopamine receptor isoform D3Short (mouse) mDRD3/iso:D3Short enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:71957|PMID:8449953 IDA NCBITaxon:10090 MGI:104771 MGI:94925 20080811 MGI:MGI PR:P30847-1 signal transduction histidine-protein kinase BaeS isoform 1 (Escherichia coli K-12) Ec-baeS/iso:1 enables GO:0004673 protein histidine kinase activity PMID:15522865 EXP NCBITaxon:83333 UniProtKB:P30847-1 20100331 PRO:CNA PR:P30999-2 catenin delta-1 isoform 2 (mouse) mCtnnd1/iso:2 located_in GO:0005634 nucleus MGI_ref:5644483|PMID:15138284 IDA NCBITaxon:10090 MGI:105100 20150722 MGI:MGI PR:P30999-2 catenin delta-1 isoform 2 (mouse) mCtnnd1/iso:2 located_in GO:0005634 nucleus MGI_ref:5644483|PMID:15138284 IMP NCBITaxon:10090 MGI:105100 20150722 MGI:MGI PR:P31809-1 CEACAM1a-4L (mouse) Bgp D (mouse)|Bgp1a/4L (mouse)|Ceacam1a isoform Long (mouse)|Ceacam1a/D1-4L (mouse)|mCEACAM1a/iso:4L acts_upstream_of_or_within GO:0032703 negative regulation of interleukin-2 production MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI:1347245 20150102 MGI:MGI occurs_in(CL:0000084) PR:P31809-1 CEACAM1a-4L (mouse) Bgp D (mouse)|Bgp1a/4L (mouse)|Ceacam1a isoform Long (mouse)|Ceacam1a/D1-4L (mouse)|mCEACAM1a/iso:4L acts_upstream_of_or_within GO:0042130 negative regulation of T cell proliferation MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI:1347245 20150102 MGI:MGI occurs_in(CL:0000084) PR:P31809-3 CEACAM1a-2L (mouse) Bgp G (mouse)|Bgp1a/4S (mouse)|BgpG (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 (mouse)|Ceacam1a/D1-2L (mouse)|mCEACAM1a/iso:3 acts_upstream_of_or_within GO:0032703 negative regulation of interleukin-2 production MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI:1347245 20150102 MGI:MGI occurs_in(CL:0000084) PR:P31809-3 CEACAM1a-2L (mouse) Bgp G (mouse)|Bgp1a/4S (mouse)|BgpG (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 (mouse)|Ceacam1a/D1-2L (mouse)|mCEACAM1a/iso:3 acts_upstream_of_or_within GO:0046329 negative regulation of JNK cascade MGI_ref:3693042|PMID:17081782 IMP NCBITaxon:10090 MGI:1347245 20150102 MGI:MGI occurs_in(CL:0000084) PR:P33434-1 72 kDa type IV collagenase isoform 1 (mouse) mMMP2/iso:1 located_in GO:0005615 extracellular space MGI_ref:5435352|PMID:22509276 IDA NCBITaxon:10090 MGI:97009 20131119 MGI:MGI PR:P33434-2 72 kDa type IV collagenase isoform 2 (mouse) mMMP2/iso:2 located_in GO:0005737 cytoplasm MGI_ref:5435352|PMID:22509276 IDA NCBITaxon:10090 MGI:97009 20131119 MGI:MGI PR:P33434-2 72 kDa type IV collagenase isoform 2 (mouse) mMMP2/iso:2 located_in GO:0005739 mitochondrion MGI_ref:5435352|PMID:22509276 IDA NCBITaxon:10090 MGI:97009 20131119 MGI:MGI part_of(MA:0000072) PR:P33434-2 72 kDa type IV collagenase isoform 2 (mouse) mMMP2/iso:2 acts_upstream_of_or_within GO:0045089 positive regulation of innate immune response MGI_ref:5435352|PMID:22509276 IDA NCBITaxon:10090 MGI:97009 20131119 MGI:MGI PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK enables GO:0005515 protein binding PR:Q12834 BioGRID:BG-590746 IPI NCBITaxon:9606 UniProtKB:P33981 20130103 PRO:KER PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O60566. Target=PR:000005188. Target=PR:Q13257. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:22660415 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O43683. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O43264. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O60566. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:P53350. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q02224. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q13257. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q9Y6D9. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902|PMID:22732840 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O43683. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902|PMID:22732840 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q5FBB7. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22732840 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q96GD4. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0045841 negative regulation of mitotic metaphase/anaphase transition PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:20624902|PMID:22732840 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:O14777. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q8NG31. PR:P33981 dual specificity protein kinase TTK (human) hTTK|MPS1|MPS1L1|phosphotyrosine picked threonine-protein kinase (human)|PYT (human)|TTK NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P33981 20121124 PRO:KER Target=PR:Q9NQS7. PR:P34820-1 bone morphogenetic protein 8B isoform 1 (human) hBMP8B/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:1460021 IDA NCBITaxon:9606 UniProtKB:P34820-1 20080301 PRO:CNA PR:P34821-1 bone morphogenetic protein 8A isoform 1 (mouse) mBMP8A/iso:1 acts_upstream_of_or_within GO:0007283 spermatogenesis PMID:9463357 IDA NCBITaxon:10090 UniProtKB:P34821-1 20080301 PRO:CNA PR:P34821-1 bone morphogenetic protein 8A isoform 1 (mouse) mBMP8A/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:9463357 IDA NCBITaxon:10090 UniProtKB:P34821-1 20080301 PRO:CNA PR:P35240-1 merlin isoform 1 (human) hNF2/iso:1 enables GO:0005515 protein binding PR:O14745 PMID:9430655 IPI NCBITaxon:9606 UniProtKB:P35240-1 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P35240-1 merlin isoform 1 (human) hNF2/iso:1 enables GO:0005515 protein binding PR:Q9H204 PMID:15467741 IPI NCBITaxon:9606 UniProtKB:P35240-1 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P35240-1 merlin isoform 1 (human) hNF2/iso:1 located_in GO:0005634 nucleus PMID:20178741 IDA NCBITaxon:9606 UniProtKB:P35240-1 20110215 PRO:CNA PR:P35240-3 merlin isoform 2 (human) hNF2/iso:2|merlin isoform II (human) enables GO:0005515 protein binding PR:Q9H204 PMID:15467741 IPI NCBITaxon:9606 UniProtKB:P35240-3 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P35240-4 merlin isoform 4 (human) hNF2/iso:4|merlin delE2/3 (human) enables GO:0005515 protein binding PR:P0DPB3-1 PMID:10669747 IPI NCBITaxon:9606 UniProtKB:P35240-4 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P35438-1 glutamate receptor ionotropic, NMDA 1 isoform long (mouse) Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)|mGRIN1/iso:1 enables GO:0004972 NMDA glutamate receptor activity MGI_ref:50809|PMID:1532151 IDA NCBITaxon:10090 MGI:95819 20080312 MGI:MGI PR:P35438-1 glutamate receptor ionotropic, NMDA 1 isoform long (mouse) Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)|mGRIN1/iso:1 enables GO:0005262 calcium channel activity MGI_ref:50809|PMID:1532151 IDA NCBITaxon:10090 MGI:95819 20080312 MGI:MGI PR:P35438-1 glutamate receptor ionotropic, NMDA 1 isoform long (mouse) Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)|mGRIN1/iso:1 located_in GO:0016020 membrane MGI_ref:50809|PMID:1532151 IC NCBITaxon:10090 GO:0004972 MGI:95819 20080312 MGI:MGI PR:P35438-1 glutamate receptor ionotropic, NMDA 1 isoform long (mouse) Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)|mGRIN1/iso:1 acts_upstream_of_or_within GO:0006816 calcium ion transport MGI_ref:50809|PMID:1532151 IDA NCBITaxon:10090 MGI:95819 20080312 MGI:MGI PR:P35438-1 glutamate receptor ionotropic, NMDA 1 isoform long (mouse) Glutamate [NMDA] receptor subunit zeta-1 isoform 1 (mouse)|mGRIN1/iso:1 acts_upstream_of_or_within GO:0042391 regulation of membrane potential MGI_ref:50809|PMID:1532151 IDA NCBITaxon:10090 MGI:95819 20080312 MGI:MGI PR:P35546-2 proto-oncogene tyrosine-protein kinase receptor Ret isoform 2 (mouse) mRET/iso:2|RET9 (mouse) acts_upstream_of_or_within GO:0001838 embryonic epithelial tube formation MGI_ref:3513229|PMID:15569713 IDA NCBITaxon:10090 MGI:97902 20080813 MGI:MGI PR:P35710-2 transcription factor SOX-5 isoform 2 (mouse) L-Sox5 (mouse)|mSOX5/iso:2 enables GO:0003677 DNA binding MGI_ref:1303256|PMID:9755172 IDA NCBITaxon:10090 MGI:98367 20081121 MGI:MGI has_participant(MGI:MGI:88452) PR:P35710-2 transcription factor SOX-5 isoform 2 (mouse) L-Sox5 (mouse)|mSOX5/iso:2 enables GO:0046982 protein heterodimerization activity PR:P40645 MGI_ref:1303256|PMID:9755172 IPI NCBITaxon:10090 MGI:98367 20081121 MGI:MGI PR:P35710-2 transcription factor SOX-5 isoform 2 (mouse) L-Sox5 (mouse)|mSOX5/iso:2 located_in GO:0005634 nucleus MGI_ref:1303256|PMID:9755172 IDA NCBITaxon:10090 MGI:98367 20081121 MGI:MGI part_of(CL:0000138) PR:P35710-2 transcription factor SOX-5 isoform 2 (mouse) L-Sox5 (mouse)|mSOX5/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1303256|PMID:9755172 IGI NCBITaxon:10090 MGI:98368|MGI:98371 MGI:98367 20081121 MGI:MGI has_regulation_target(MGI:MGI:88452) PR:P35710-3 transcription factor SOX-5 isoform 3 (mouse) mSOX5/iso:3|S-Sox5 (mouse) enables GO:0000976 transcription cis-regulatory region binding MGI_ref:4849623|PMID:20668334 IDA NCBITaxon:10090 MGI:98367 20110307 MGI:MGI PR:P35710-3 transcription factor SOX-5 isoform 3 (mouse) mSOX5/iso:3|S-Sox5 (mouse) located_in GO:0005634 nucleus MGI_ref:4849623|PMID:20668334 IDA NCBITaxon:10090 MGI:98367 20110307 MGI:MGI PR:P35710-3 transcription factor SOX-5 isoform 3 (mouse) mSOX5/iso:3|S-Sox5 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4849623|PMID:20668334 IDA NCBITaxon:10090 MGI:98367 20110307 MGI:MGI PR:P35969 vascular endothelial growth factor receptor 1 (mouse) embryonic receptor kinase 2 (mouse)|Emrk2|Flt|FLT-1 (mouse)|Flt1|fms-like tyrosine kinase 1 (mouse)|mFLT1|tyrosine-protein kinase receptor FLT (mouse)|VEGFR-1 (mouse)|Vegfr1 acts_upstream_of_or_within GO:0001569 branching involved in blood vessel morphogenesis PMID:14982871 IMP NCBITaxon:10090 MGI_allele:1857717 UniProtKB:P35969 20100505 PRO:HJD PR:P35969 vascular endothelial growth factor receptor 1 (mouse) embryonic receptor kinase 2 (mouse)|Emrk2|Flt|FLT-1 (mouse)|Flt1|fms-like tyrosine kinase 1 (mouse)|mFLT1|tyrosine-protein kinase receptor FLT (mouse)|VEGFR-1 (mouse)|Vegfr1 acts_upstream_of_or_within GO:0002040 sprouting angiogenesis PMID:19758562 IMP NCBITaxon:10090 MGI_allele:1857717 UniProtKB:P35969 20100505 PRO:HJD PR:P35969 vascular endothelial growth factor receptor 1 (mouse) embryonic receptor kinase 2 (mouse)|Emrk2|Flt|FLT-1 (mouse)|Flt1|fms-like tyrosine kinase 1 (mouse)|mFLT1|tyrosine-protein kinase receptor FLT (mouse)|VEGFR-1 (mouse)|Vegfr1 acts_upstream_of_or_within GO:0048010 vascular endothelial growth factor receptor signaling pathway PMID:9689083 IMP NCBITaxon:10090 MGI_allele:1934260 UniProtKB:P35969 20100505 PRO:HJD PR:P35969-1 vascular endothelial growth factor receptor 1 isoform 1 (mouse) mFLT1/iso:1 NOT acts_upstream_of_or_within GO:0002040 sprouting angiogenesis PMID:19758562 EXP NCBITaxon:10090 UniProtKB:P35969-1 20100505 PRO:HJD PR:P36894-1 bone morphogenetic protein receptor type-1A isoform 1 (human) hBMPR1A/iso:1 located_in GO:0016020 membrane PMID:8397373 TAS NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:P36894-1 bone morphogenetic protein receptor type-1A isoform 1 (human) hBMPR1A/iso:1 part_of GO:0043235 receptor complex PMID:15940369 IDA NCBITaxon:9606 UniProtKB:P36894-1 20080301 PRO:CNA PR:P36895-1 bone morphogenetic protein receptor type-1A isoform 1 (mouse) mBMPR1A/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:10814522 IDA NCBITaxon:10090 UniProtKB:P36895-1 20080301 PRO:CNA PR:P36896-1 activin receptor type-1B isoform 1 (human) activin receptor type-1B isoform SKR2-1 (human)|hACVR1B/iso:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:11069203 IDA NCBITaxon:9606 UniProtKB:P36896-1 20080301 PRO:CNA PR:P36896-2 activin receptor type-1B isoform 2 (human) activin receptor type-1B isoform SKR2-2 (human)|hACVR1B/iso:2 located_in GO:0005886 plasma membrane PMID:11117535|PMID:8636304 IDA NCBITaxon:9606 UniProtKB:P36896-2 20080301 PRO:CNA PR:P36896-2 activin receptor type-1B isoform 2 (human) activin receptor type-1B isoform SKR2-2 (human)|hACVR1B/iso:2 NOT enables GO:0016361 activin receptor activity, type I PMID:11117535|PMID:8636304 IDA NCBITaxon:9606 UniProtKB:P36896-2 20080301 PRO:CNA PR:P36896-3 activin receptor type-1B isoform 3 (human) activin receptor type-1B isoform SKR2-3 (human)|hACVR1B/iso:3 located_in GO:0005886 plasma membrane PMID:11117535|PMID:8636304 IDA NCBITaxon:9606 UniProtKB:P36896-3 20080301 PRO:CNA PR:P36896-3 activin receptor type-1B isoform 3 (human) activin receptor type-1B isoform SKR2-3 (human)|hACVR1B/iso:3 NOT enables GO:0016361 activin receptor activity, type I PMID:11117535|PMID:8636304 IDA NCBITaxon:9606 UniProtKB:P36896-3 20080301 PRO:CNA PR:P36897-1 TGF-beta receptor type-1 isoform 1 (human) hTGFBR1/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8242743 TAS NCBITaxon:9606 UniProtKB:P36897-1 20080301 PRO:CNA PR:P36898-1 bone morphogenetic protein receptor type-1B isoform 1 (mouse) mBMPR1B/iso:1 located_in GO:0009986 cell surface PMID:10712517 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:P36898-1 bone morphogenetic protein receptor type-1B isoform 1 (mouse) mBMPR1B/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:P36898-1 bone morphogenetic protein receptor type-1B isoform 1 (mouse) mBMPR1B/iso:1 acts_upstream_of_or_within GO:0001502 cartilage condensation PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:P36898-1 bone morphogenetic protein receptor type-1B isoform 1 (mouse) mBMPR1B/iso:1 acts_upstream_of_or_within GO:0035108 limb morphogenesis PMID:14523231 IDA NCBITaxon:10090 UniProtKB:P36898-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8242742|PMID:9245985 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0005025 transforming growth factor beta receptor activity, type I PMID:8242742 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0016361 activin receptor activity, type I PMID:8242742 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0046332 SMAD binding PMID:9920917 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0048185 activin binding PMID:8242742 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 enables GO:0050431 transforming growth factor beta binding PMID:8242742 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 located_in GO:0005886 plasma membrane PMID:8242742|PMID:8397373 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 located_in GO:0009986 cell surface PMID:8242742 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 acts_upstream_of_or_within GO:0001525 angiogenesis PMID:12453878 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:9920917 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37023-1 serine/threonine-protein kinase receptor R3 isoform 1 (human) hACVRL1/iso:1 acts_upstream_of_or_within GO:0008015 blood circulation PMID:9245985 IDA NCBITaxon:9606 UniProtKB:P37023-1 20080301 PRO:CNA PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human) hTGFBR2/iso:RII-2|TGF-beta receptor type-2 isoform 2 (human)|TGFBR2 isoform 2 (human) enables GO:0005026 transforming growth factor beta receptor activity, type II PMID:7959019|PMID:8635485 EXP NCBITaxon:9606 UniProtKB:P37173-2 20080301 PRO:CNA PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human) hTGFBR2/iso:RII-2|TGF-beta receptor type-2 isoform 2 (human)|TGFBR2 isoform 2 (human) enables GO:0050431 transforming growth factor beta binding PMID:8635485 EXP NCBITaxon:9606 UniProtKB:P37173-2 20080301 PRO:CNA PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human) hTGFBR2/iso:RII-2|TGF-beta receptor type-2 isoform 2 (human)|TGFBR2 isoform 2 (human) acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:7959019|PMID:8635485 EXP NCBITaxon:9606 UniProtKB:P37173-2 20080301 PRO:CNA PR:P37173-2 TGF-beta receptor type-2 isoform RII-2 (human) hTGFBR2/iso:RII-2|TGF-beta receptor type-2 isoform 2 (human)|TGFBR2 isoform 2 (human) acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:7959019 EXP NCBITaxon:9606 UniProtKB:P37173-2 20080301 PRO:CNA PR:P37238-2 peroxisome proliferator-activated receptor gamma isoform 1 (mouse) mPPARG/iso:1 acts_upstream_of_or_within GO:0045444 fat cell differentiation MGI_ref:5528597|PMID:23840343 IMP NCBITaxon:10090 MGI:97747 20150318 MGI:MGI occurs_in(CL:0002334) PR:P37238-2 peroxisome proliferator-activated receptor gamma isoform 1 (mouse) mPPARG/iso:1 acts_upstream_of_or_within GO:0045600 positive regulation of fat cell differentiation MGI_ref:5309089|PMID:22226965 IDA NCBITaxon:10090 MGI:97747 20140729 MGI:MGI PR:P37238-2 peroxisome proliferator-activated receptor gamma isoform 1 (mouse) mPPARG/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:5309089|PMID:22226965 IDA NCBITaxon:10090 MGI:97747 20131125 MGI:MGI PR:P38060-1 hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (mouse) mHMGCL/iso:1 located_in GO:0005739 mitochondrion PMID:14651853|PMID:18614015 EXP NCBITaxon:10090 UniProtKB:P38060-1 20100614 PRO:HJD PR:P38060-1 hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (mouse) mHMGCL/iso:1 located_in GO:0005743 mitochondrial inner membrane PMID:12865426 EXP NCBITaxon:10090 UniProtKB:P38060-1 20100614 PRO:HJD PR:P38398-5 breast cancer type 1 susceptibility protein isoform 5 (human) hBRCA1/iso:5 enables GO:0005515 protein binding PR:Q92560 PMID:9528852 IPI NCBITaxon:9606 UniProtKB:P38398-5 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P38991 spindle assembly checkpoint kinase (yeast) aurora kinase (yeast)|increase-in-ploidy protein 1 (yeast)|IPL1|yIPL1|YPL209C enables GO:0004672 protein kinase activity PMID:17504936 EXP NCBITaxon:4932 UniProtKB:P38991 20121121 PRO:KER PR:P39087-1 glutamate receptor ionotropic, kainate 2 isoform 1 (mouse) GluR6 Beta2 (mouse)|mGRIK2/iso:1 located_in GO:0016020 membrane MGI_ref:3574145|PMID:15014126 IDA NCBITaxon:10090 MGI:95815 20080514 MGI:MGI PR:P39087-2 glutamate receptor ionotropic, kainate 2 isoform 2 (mouse) GluR6-2 (mouse)|mGRIK2/iso:2 located_in GO:0016020 membrane MGI_ref:3574145|PMID:15014126 IDA NCBITaxon:10090 MGI:95815 20140327 MGI:MGI PR:P39087-2 glutamate receptor ionotropic, kainate 2 isoform 2 (mouse) GluR6-2 (mouse)|mGRIK2/iso:2 acts_upstream_of_or_within GO:0006886 intracellular protein transport MGI_ref:3574145|PMID:15014126 IDA NCBITaxon:10090 MGI:95815 20080514 MGI:MGI PR:P39087-2 glutamate receptor ionotropic, kainate 2 isoform 2 (mouse) GluR6-2 (mouse)|mGRIK2/iso:2 acts_upstream_of_or_within GO:0060079 excitatory postsynaptic potential MGI_ref:3708428|PMID:17428973 IGI NCBITaxon:10090 MGI:107164 MGI:95815 20080109 MGI:MGI occurs_in(MA:0000952),regulates_o_occurs_in(CL:0000598) PR:P39087-2 glutamate receptor ionotropic, kainate 2 isoform 2 (mouse) GluR6-2 (mouse)|mGRIK2/iso:2 acts_upstream_of_or_within GO:0060079 excitatory postsynaptic potential MGI_ref:3708428|PMID:17428973 IMP NCBITaxon:10090 MGI_allele:1857979 MGI:95815 20080109 MGI:MGI occurs_in(MA:0000952),regulates_o_occurs_in(CL:0000598) PR:P39453-1 sensor protein TorS isoform 1 (Escherichia coli K-12) Ec-torS/iso:1 enables GO:0005515 protein binding PR:000036781 PMID:17040909 IPI NCBITaxon:83333 UniProtKB:P39453-1 20100510 PRO:CNA PR:P40336-1 vacuolar protein sorting-associated protein 26A isoform 1 (mouse) mVPS26A/iso:1 located_in GO:0005768 endosome PMID:15078902 IDA NCBITaxon:10090 UniProtKB:P40336-1 20100312 PRO:HJD PR:P40336-1 vacuolar protein sorting-associated protein 26A isoform 1 (mouse) mVPS26A/iso:1 acts_upstream_of_or_within GO:0042147 retrograde transport, endosome to Golgi PMID:15078902 IDA NCBITaxon:10090 UniProtKB:P40336-1 20100312 PRO:HJD PR:P40336-2 vacuolar protein sorting-associated protein 26A isoform 2 (mouse) mVPS26A/iso:2 enables GO:0005515 protein binding PR:Q9EQH3 MGI_ref:3807094|PMID:18656452 IPI NCBITaxon:10090 MGI:1353654 20100312 MGI:MGI PR:P40337-3 von Hippel-Lindau disease tumor suppressor isoform 3 (human) hVHL/iso:3 enables GO:0005515 protein binding PR:O75912 PMID:17986458 IPI NCBITaxon:9606 UniProtKB:P40337-3 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:P28288 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:P33897 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:P56589 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:Q7Z412 PMID:15713480 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070918 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:Q9UBJ2 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 enables GO:0005515 protein binding PR:Q9Y5Y5 PMID:15713480 IPI NCBITaxon:9606 UniProtKB:P40855-1 20070918 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 located_in GO:0005634 nucleus PMID:12924628 IMP NCBITaxon:9606 UniProtKB:P40855-1 20070913 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 located_in GO:0005737 cytoplasm PMID:10051604 IDA NCBITaxon:9606 UniProtKB:P40855-1 20070921 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 located_in GO:0005737 cytoplasm PMID:12924628 IMP NCBITaxon:9606 UniProtKB:P40855-1 20070913 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 located_in GO:0005778 peroxisomal membrane PMID:15713480 IDA NCBITaxon:9606 UniProtKB:P40855-1 20070918 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 located_in GO:0016020 membrane PMID:10051604 IDA NCBITaxon:9606 UniProtKB:P40855-1 20070921 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 acts_upstream_of_or_within GO:0007031 peroxisome organization PMID:11883941 IMP NCBITaxon:9606 UniProtKB:P40855-1 20070913 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 acts_upstream_of_or_within GO:0007031 peroxisome organization PMID:12924628 IMP NCBITaxon:9606 UniProtKB:P40855-1 20070913 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-1 peroxisomal biogenesis factor 19 isoform 1 (human) hPEX19/iso:1 acts_upstream_of_or_within GO:0016557 peroxisome membrane biogenesis PMID:10051604 IDA NCBITaxon:9606 UniProtKB:P40855-1 20070921 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-2 peroxisomal biogenesis factor 19 isoform 2 (human) hPEX19/iso:2 enables GO:0005515 protein binding PR:P28288 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-2 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-2 peroxisomal biogenesis factor 19 isoform 2 (human) hPEX19/iso:2 enables GO:0005515 protein binding PR:P33897 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-2 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-2 peroxisomal biogenesis factor 19 isoform 2 (human) hPEX19/iso:2 enables GO:0005515 protein binding PR:P56589 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-2 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-2 peroxisomal biogenesis factor 19 isoform 2 (human) hPEX19/iso:2 enables GO:0005515 protein binding PR:Q9UBJ2 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-2 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-4 peroxisomal biogenesis factor 19 isoform 4 (human) hPEX19/iso:4 enables GO:0005515 protein binding PR:P28288 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-4 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-4 peroxisomal biogenesis factor 19 isoform 4 (human) hPEX19/iso:4 enables GO:0005515 protein binding PR:P33897 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-4 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-4 peroxisomal biogenesis factor 19 isoform 4 (human) hPEX19/iso:4 enables GO:0005515 protein binding PR:P56589 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-4 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-4 peroxisomal biogenesis factor 19 isoform 4 (human) hPEX19/iso:4 enables GO:0005515 protein binding PR:Q9UBJ2 PMID:11883941 IPI NCBITaxon:9606 UniProtKB:P40855-4 20070912 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40855-4 peroxisomal biogenesis factor 19 isoform 4 (human) hPEX19/iso:4 acts_upstream_of_or_within GO:0007031 peroxisome organization PMID:11883941 IMP NCBITaxon:9606 UniProtKB:P40855-4 20070913 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:P40958 mitotic spindle checkpoint component MAD2 (yeast) J1256|MAD2|mitotic MAD2 protein (yeast)|YJL030W|yMAD2L1 acts_upstream_of_or_within GO:0006974 DNA damage response PMID:15514023 EXP NCBITaxon:4932 UniProtKB:P40958 20121121 PRO:KER PR:P40958 mitotic spindle checkpoint component MAD2 (yeast) J1256|MAD2|mitotic MAD2 protein (yeast)|YJL030W|yMAD2L1 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:17504936 EXP NCBITaxon:4932 UniProtKB:P40958 20121121 PRO:KER PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse) mFASLG/iso:FasL located_in GO:0005886 plasma membrane PMID:16973387 IDA NCBITaxon:10090 UniProtKB:P41047-1 20080301 PRO:CNA PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse) mFASLG/iso:FasL located_in GO:0009986 cell surface PMID:16973387 IDA NCBITaxon:10090 UniProtKB:P41047-1 20080301 PRO:CNA PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse) mFASLG/iso:FasL acts_upstream_of_or_within GO:0006915 apoptotic process PMID:16365167 IDA NCBITaxon:10090 UniProtKB:P41047-1 20080301 PRO:CNA PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse) mFASLG/iso:FasL acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:76989|PMID:7595210 IDA NCBITaxon:10090 MGI:95484 20080109 MGI:MGI PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse) mFASLG/iso:FasL acts_upstream_of_or_within GO:0097190 apoptotic signaling pathway PMID:15039234 IDA NCBITaxon:10090 UniProtKB:P41047-1 20080301 PRO:CNA PR:P41047-2 tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse) mFASLG/iso:FasLS located_in GO:0005615 extracellular space PMID:10552956 IDA NCBITaxon:10090 UniProtKB:P41047-2 20080301 PRO:CNA PR:P41047-2 tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse) mFASLG/iso:FasLS acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:10552956 IDA NCBITaxon:10090 UniProtKB:P41047-2 20080301 PRO:CNA PR:P41133-1 DNA-binding protein inhibitor ID-3 isoform 1 (mouse) mID3/iso:1 located_in GO:0005634 nucleus PMID:15451666 IDA NCBITaxon:10090 UniProtKB:P41133-1 20080301 PRO:CNA PR:P41133-1 DNA-binding protein inhibitor ID-3 isoform 1 (mouse) mID3/iso:1 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:2000388 IDA NCBITaxon:10090 UniProtKB:P41133-1 20080301 PRO:CNA PR:P41134 DNA-binding protein inhibitor ID-1 (human) BHLHB24|class B basic helix-loop-helix protein 24 (human)|hID1|ID|ID1|inhibitor of differentiation 1 (human)|inhibitor of DNA binding 1 (human) located_in GO:0005634 nucleus PMID:15138269 EXP NCBITaxon:9606 UniProtKB:P41134 20080301 PRO:CNA PR:P41134 DNA-binding protein inhibitor ID-1 (human) BHLHB24|class B basic helix-loop-helix protein 24 (human)|hID1|ID|ID1|inhibitor of differentiation 1 (human)|inhibitor of DNA binding 1 (human) acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:15138269 EXP NCBITaxon:9606 UniProtKB:P41134 20080301 PRO:CNA PR:P41134-1 DNA-binding protein inhibitor ID-1 isoform ID-A (human) hID1/iso:ID-A enables GO:0005515 protein binding PR:Q03135 PMID:17855368 IPI NCBITaxon:9606 UniProtKB:P41134-1 20080301 PRO:CNA PR:P41134-1 DNA-binding protein inhibitor ID-1 isoform ID-A (human) hID1/iso:ID-A located_in GO:0005737 cytoplasm PMID:17855368 IDA NCBITaxon:9606 UniProtKB:P41134-1 20080301 PRO:CNA PR:P41134-1 DNA-binding protein inhibitor ID-1 isoform ID-A (human) hID1/iso:ID-A acts_upstream_of_or_within GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction PMID:17855368 IDA NCBITaxon:9606 UniProtKB:P41134-1 20080301 PRO:CNA PR:P41136-1 DNA-binding protein inhibitor ID-2 isoform 1 (mouse) mID2/iso:1 enables GO:0046983 protein dimerization activity PMID:10891368 IDA NCBITaxon:10090 UniProtKB:P41136-1 20151104 PRO:CNA PR:P41136-1 DNA-binding protein inhibitor ID-2 isoform 1 (mouse) mID2/iso:1 located_in GO:0005634 nucleus PMID:12878164 IDA NCBITaxon:10090 UniProtKB:P41136-1 20151104 PRO:CNA PR:P41136-1 DNA-binding protein inhibitor ID-2 isoform 1 (mouse) mID2/iso:1 located_in GO:0005737 cytoplasm PMID:12878164|PMID:15563451 IDA NCBITaxon:10090 UniProtKB:P41136-1 20151104 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 enables GO:0005515 protein binding PR:Q03135 PMID:15280210 IPI NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 enables GO:0005515 protein binding PR:Q9JKN5 PMID:15280210 IPI NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 located_in GO:0005737 cytoplasm PMID:15280210 IDA NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation PMID:15882580 IDA NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:15280210 IDA NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 acts_upstream_of_or_within GO:0045665 negative regulation of neuron differentiation PMID:15882580 IDA NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41139-1 DNA-binding protein inhibitor ID-4 isoform 1 (mouse) mID4/iso:1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:8139914 IDA NCBITaxon:10090 UniProtKB:P41139-1 20080301 PRO:CNA PR:P41695 checkpoint serine/threonine-protein kinase BUB1 (yeast) BUB1|G7542|yBUB1|YGR188C enables GO:0005515 protein binding PR:000035536 PMID:22521787 IPI NCBITaxon:4932 UniProtKB:P41695 20121121 PRO:KER PR:P41695 checkpoint serine/threonine-protein kinase BUB1 (yeast) BUB1|G7542|yBUB1|YGR188C enables GO:0005515 protein binding PR:P26449 PMID:7969164 IPI NCBITaxon:4932 UniProtKB:P41695 20121121 PRO:KER PR:P41695 checkpoint serine/threonine-protein kinase BUB1 (yeast) BUB1|G7542|yBUB1|YGR188C located_in GO:0000776 kinetochore PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P41695 20121121 PRO:KER PR:P41695 checkpoint serine/threonine-protein kinase BUB1 (yeast) BUB1|G7542|yBUB1|YGR188C acts_upstream_of_or_within GO:0006974 DNA damage response PMID:15514023 EXP NCBITaxon:4932 UniProtKB:P41695 20121121 PRO:KER PR:P42345 serine/threonine-protein kinase mTOR (human) FK506-binding protein 12-rapamycin complex-associated protein 1 (human)|FKBP12-rapamycin complex-associated protein (human)|FRAP|FRAP1|FRAP2|hMTOR|mammalian target of rapamycin (human)|mechanistic target of rapamycin (human)|MTOR|mTOR (human)|RAFT1|rapamycin and FKBP12 target 1 (human)|rapamycin target protein 1 (human)|RAPT1 enables GO:0005515 protein binding PR:000035446 PMID:11602639 IPI NCBITaxon:9606 UniProtKB:P42345 20090713 PRO:CL PR:P42345 serine/threonine-protein kinase mTOR (human) FK506-binding protein 12-rapamycin complex-associated protein 1 (human)|FKBP12-rapamycin complex-associated protein (human)|FRAP|FRAP1|FRAP2|hMTOR|mammalian target of rapamycin (human)|mechanistic target of rapamycin (human)|MTOR|mTOR (human)|RAFT1|rapamycin and FKBP12 target 1 (human)|rapamycin target protein 1 (human)|RAPT1 located_in GO:0005634 nucleus PMID:11602639 EXP NCBITaxon:9606 UniProtKB:P42345 20090713 PRO:CL PR:P42345 serine/threonine-protein kinase mTOR (human) FK506-binding protein 12-rapamycin complex-associated protein 1 (human)|FKBP12-rapamycin complex-associated protein (human)|FRAP|FRAP1|FRAP2|hMTOR|mammalian target of rapamycin (human)|mechanistic target of rapamycin (human)|MTOR|mTOR (human)|RAFT1|rapamycin and FKBP12 target 1 (human)|rapamycin target protein 1 (human)|RAPT1 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11602639 EXP NCBITaxon:9606 UniProtKB:P42345 20090713 PRO:CL PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human) cyclin-dependent kinase 4 inhibitor B isoform p15 (human)|hCDKN2B/iso:1 enables GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PMID:8078588 IDA NCBITaxon:9606 UniProtKB:P42772-1 20080301 PRO:CNA PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human) cyclin-dependent kinase 4 inhibitor B isoform p15 (human)|hCDKN2B/iso:1 enables GO:0005515 protein binding PMID:16169070 IPI NCBITaxon:9606 UniProtKB:P42772-1 20080301 PRO:CNA PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human) cyclin-dependent kinase 4 inhibitor B isoform p15 (human)|hCDKN2B/iso:1 acts_upstream_of_or_within GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity PMID:8078588 IDA NCBITaxon:9606 UniProtKB:P42772-1 20080301 PRO:CNA PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human) cyclin-dependent kinase 4 inhibitor B isoform p15 (human)|hCDKN2B/iso:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:8078588 IDA NCBITaxon:9606 UniProtKB:P42772-1 20080301 PRO:CNA PR:P42772-1 cyclin-dependent kinase 4 inhibitor B isoform 1 (human) cyclin-dependent kinase 4 inhibitor B isoform p15 (human)|hCDKN2B/iso:1 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:8078588 IDA NCBITaxon:9606 UniProtKB:P42772-1 20080301 PRO:CNA PR:P43021-1 nodal isoform 1 (mouse) mNODAL/iso:1 enables GO:0042803 protein homodimerization activity PMID:15649361 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA PR:P43021-1 nodal isoform 1 (mouse) mNODAL/iso:1 located_in GO:0005615 extracellular space PMID:15649361 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA PR:P43021-1 nodal isoform 1 (mouse) mNODAL/iso:1 acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:12654299 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA PR:P43021-1 nodal isoform 1 (mouse) mNODAL/iso:1 acts_upstream_of_or_within GO:0009952 anterior/posterior pattern specification PMID:15004567 IDA NCBITaxon:10090 UniProtKB:P43021-1 20080301 PRO:CNA PR:P43026-1 growth/differentiation factor 5 isoform 1 (human) hGDF5/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:7961761 TAS NCBITaxon:9606 UniProtKB:P43026-1 20080301 PRO:CNA PR:P43026-1 growth/differentiation factor 5 isoform 1 (human) hGDF5/iso:1 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:8589725 TAS NCBITaxon:9606 UniProtKB:P43026-1 20080301 PRO:CNA PR:P43029 growth/differentiation factor 7 (mouse) Gdf-7|GDF-7 (mouse)|Gdf7|mGDF7 acts_upstream_of_or_within GO:0045165 cell fate commitment PMID:15883363 IDA NCBITaxon:10090 UniProtKB:P43029 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 enables GO:0004402 histone acetyltransferase activity PMID:11867645 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 enables GO:0005515 protein binding PR:P02340 PMID:9194565 IPI NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 enables GO:0005515 protein binding PR:P88946 PMID:10733899 IPI NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 enables GO:0005515 protein binding PR:Q60749 PMID:12496368 IPI NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 enables GO:0016407 acetyltransferase activity PMID:12496368 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 located_in GO:0005634 nucleus PMID:11963968|PMID:12496368 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45481-1 CREB-binding protein isoform 1 (mouse) mCREBBP/iso:1 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:15464984 IDA NCBITaxon:10090 UniProtKB:P45481-1 20080301 PRO:CNA PR:P45973 chromobox protein homolog 5 (human) antigen p25 (human)|CBX5|hCBX5|heterochromatin protein 1 homolog alpha (human)|HP1 alpha (human)|HP1A enables GO:0035064 methylated histone binding PR:000044878 PMID:16127177 IPI NCBITaxon:9606 UniProtKB:P45973 20151112 PRO:CNA PR:P45973 chromobox protein homolog 5 (human) antigen p25 (human)|CBX5|hCBX5|heterochromatin protein 1 homolog alpha (human)|HP1 alpha (human)|HP1A NOT enables GO:0035064 methylated histone binding PR:000045400 PMID:16127177 IPI NCBITaxon:9606 UniProtKB:P10412 20151112 PRO:CNA PR:P47074 spindle assembly checkpoint component MAD3 (yeast) J1341|MAD3|Mitotic MAD3 protein|mitotic MAD3 protein (yeast)|YJL013C|yMAD3 enables GO:0005515 protein binding PR:P26309 IntAct:EBI-1269178 IPI NCBITaxon:4932 UniProtKB:P47074 20121121 PRO:KER PR:P47074 spindle assembly checkpoint component MAD3 (yeast) J1341|MAD3|Mitotic MAD3 protein|mitotic MAD3 protein (yeast)|YJL013C|yMAD3 enables GO:0005515 protein binding PR:P26449 IntAct:EBI-1269169 IPI NCBITaxon:4932 UniProtKB:P47074 20121121 PRO:KER PR:P47074 spindle assembly checkpoint component MAD3 (yeast) J1341|MAD3|Mitotic MAD3 protein|mitotic MAD3 protein (yeast)|YJL013C|yMAD3 enables GO:0005515 protein binding PR:P40958 IntAct:EBI-1269217 IPI NCBITaxon:4932 UniProtKB:P47074 20121121 PRO:KER PR:P47074 spindle assembly checkpoint component MAD3 (yeast) J1341|MAD3|Mitotic MAD3 protein|mitotic MAD3 protein (yeast)|YJL013C|yMAD3 acts_upstream_of_or_within GO:0006974 DNA damage response PMID:15514023 EXP NCBITaxon:4932 UniProtKB:P47074 20121121 PRO:KER PR:P47074 spindle assembly checkpoint component MAD3 (yeast) J1341|MAD3|Mitotic MAD3 protein|mitotic MAD3 protein (yeast)|YJL013C|yMAD3 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:15970700 EXP NCBITaxon:4932 UniProtKB:P47074 20121121 PRO:KER PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse) CAPZ beta 1 (mouse)|CAPZ beta-1 (mouse)|CAPZB1 (mouse)|mCAPZB/iso:1 located_in GO:0030018 Z disc MGI_ref:1350695|PMID:10601341 IDA NCBITaxon:10090 MGI:104652 20130308 MGI:MGI part_of(MA:0000072) PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse) CAPZ beta 1 (mouse)|CAPZ beta-1 (mouse)|CAPZB1 (mouse)|mCAPZB/iso:1 located_in GO:0030018 Z disc MGI_ref:68935|PMID:7929588 ISA NCBITaxon:10090 EMBL:J04959|UniProtKB:P14315-1 MGI:104652 20080321 MGI:MGI part_of(MA:0000072),part_of(CL:0000187) PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse) CAPZ beta 1 (mouse)|CAPZ beta-1 (mouse)|CAPZB1 (mouse)|mCAPZB/iso:1 acts_upstream_of_or_within GO:0055001 muscle cell development MGI_ref:1350695|PMID:10601341 IMP NCBITaxon:10090 MGI:104652 20130308 MGI:MGI occurs_in(MA:0000072) PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse) CAPZ beta 1 (mouse)|CAPZ beta-1 (mouse)|CAPZB1 (mouse)|mCAPZB/iso:1 acts_upstream_of_or_within GO:0090036 regulation of protein kinase C signaling MGI_ref:3777904|PMID:12089068 IMP NCBITaxon:10090 MGI:104652 20130403 MGI:MGI regulates_o_occurs_in(MA:0000072) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 enables GO:0048487 beta-tubulin binding PR:Q9ERD7 MGI_ref:4397629|PMID:19806181 IPI NCBITaxon:10090 MGI:104652 20130417 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 part_of GO:0008290 F-actin capping protein complex MGI_ref:3773286|PMID:11604420 IDA NCBITaxon:10090 MGI:104652 20130307 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 part_of GO:0008290 F-actin capping protein complex PR:P47754 MGI_ref:4397629|PMID:19806181 IPI NCBITaxon:10090 MGI:104652 20130417 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 located_in GO:0014704 intercalated disc MGI_ref:1350695|PMID:10601341 IDA NCBITaxon:10090 MGI:104652 20130308 MGI:MGI part_of(MA:0000072) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 located_in GO:0014704 intercalated disc MGI_ref:68935|PMID:7929588 ISA NCBITaxon:10090 EMBL:U07826|UniProtKB:P14315-2 MGI:104652 20080612 MGI:MGI part_of(MA:0000072),part_of(CL:0000187) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 acts_upstream_of_or_within GO:0030032 lamellipodium assembly MGI_ref:4397629|PMID:19806181 IMP NCBITaxon:10090 MGI:104652 20130311 MGI:MGI occurs_in(CL:0002608) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 acts_upstream_of_or_within GO:0031115 negative regulation of microtubule polymerization MGI_ref:4397629|PMID:19806181 IDA NCBITaxon:10090 MGI:104652 20130311 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 acts_upstream_of_or_within GO:0031175 neuron projection development MGI_ref:4397629|PMID:19806181 IMP NCBITaxon:10090 MGI:4397629 MGI:104652 20130311 MGI:MGI occurs_in(CL:0002608) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 acts_upstream_of_or_within GO:0055001 muscle cell development MGI_ref:1350695|PMID:10601341 IMP NCBITaxon:10090 MGI:1350695 MGI:104652 20140214 MGI:MGI occurs_in(MA:0000072) PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 acts_upstream_of_or_within GO:0051016 barbed-end actin filament capping MGI_ref:3758397|PMID:17656356 IDA NCBITaxon:10090 MGI:104652 20130307 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 contributes_to enables GO:0005515 protein binding PR:Q91YR1 MGI_ref:3773286|PMID:11604420 IPI NCBITaxon:10090 MGI:104652 20130416 MGI:MGI PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse) CAPZ beta 2 (mouse)|CAPZ beta-2 (mouse)|CAPZB2 (mouse)|mCAPZB/iso:2 contributes_to enables GO:0051015 actin filament binding MGI_ref:3758397|PMID:17656356 IDA NCBITaxon:10090 MGI:104652 20130306 MGI:MGI PR:P47757-4 F-actin-capping protein subunit beta isoform Capzb3 (mouse) Capzb isoform 3 (mouse)|Capzb3 (mouse)|mCAPZB/iso:Capzb3 colocalizes_with located_in GO:0001669 acrosomal vesicle MGI_ref:3848085|PMID:19341723 IDA NCBITaxon:10090 MGI:104652 20130311 MGI:MGI PR:P47811-1 mitogen-activated protein kinase 14 isoform 1 (mouse) mMAPK14/iso:1 acts_upstream_of_or_within GO:0014835 myoblast differentiation involved in skeletal muscle regeneration MGI_ref:4838005|PMID:20610565 IMP NCBITaxon:10090 MGI:1346865 20140305 MGI:MGI occurs_in(CL:0000056) PR:P47857-1 ATP-dependent 6-phosphofructokinase, muscle type isoform 1 (mouse) mPFKM/iso:1 enables GO:0005515 protein binding PR:P17710-1|PR:P48774 MGI_ref:4443253|PMID:19889946 IPI NCBITaxon:10090 MGI:97548 20131213 MGI:MGI occurs_in(CL:0000019) PR:P47928-1 DNA-binding protein inhibitor ID-4 isoform 1 (human) hID4/iso:1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:11136250 IDA NCBITaxon:9606 UniProtKB:P47928-1 20080301 PRO:CNA PR:P47939-1 regulated endocrine-specific protein 18 isoform 1 (mouse) mRESP18/iso:1 located_in GO:0005783 endoplasmic reticulum MGI_ref:1097585|PMID:7988462 IDA NCBITaxon:10090 MGI:1098222 20010928 MGI:MGI PR:P48023-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (human) FASLG isoform 1 (human)|hFASLG/iso:FasL|tumor necrosis factor ligand superfamily member 6 isoform 1 (human) acts_upstream_of_or_within GO:0043123 positive regulation of canonical NF-kappaB signal transduction PMID:12761501 IDA NCBITaxon:9606 UniProtKB:P48023-1 20080301 PRO:CNA PR:P49003 bone morphogenetic protein 5 (mouse) Bmp-5|BMP-5 (mouse)|Bmp5|mBMP5 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:2263636 IDA NCBITaxon:10090 UniProtKB:P49003 20080301 PRO:CNA PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0006778 porphyrin-containing compound metabolic process PMID:4404581 IMP NCBITaxon:10090 MGI_allele:1856400 UniProtKB:P49282 20090717 PRO:HJD PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0007611 learning or memory PMID:19211831 IMP NCBITaxon:10090 MGI_allele:2177768|MGI_allele:3577916 UniProtKB:P49282 20090717 PRO:HJD PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0006826 iron ion transport PMID:807277 IMP NCBITaxon:10090 MGI_allele:1856400 UniProtKB:P49282 20090717 PRO:HJD PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0048813 dendrite morphogenesis PMID:19211831 IMP NCBITaxon:10090 MGI_allele:2177768|MGI_allele:3577916 UniProtKB:P49282 20090717 PRO:HJD PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0048821 erythrocyte development PMID:15849611 IMP NCBITaxon:10090 MGI_allele:3577914 UniProtKB:P49282 20090717 PRO:HJD PR:P49282 natural resistance-associated macrophage protein 2 (mouse) Dct1|divalent cation transporter 1 (mouse)|divalent metal transporter 1 (mouse)|DMT-1 (mouse)|Dmt1|mSLC11A2|NRAMP 2 (mouse)|Nramp2|Slc11a2|solute carrier family 11 member 2 (mouse) acts_upstream_of_or_within GO:0060586 multicellular organismal-level iron ion homeostasis PMID:5070129 IMP NCBITaxon:10090 MGI_allele:1856400 UniProtKB:P49282 20090717 PRO:HJD PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) enables GO:0015078 proton transmembrane transporter activity MGI_ref:3037617|PMID:15024413 IDA NCBITaxon:10090 MGI:1345279 20090716 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) enables GO:0015087 cobalt ion transmembrane transporter activity MGI_ref:3695780|PMID:16905747 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) enables GO:0015087 cobalt ion transmembrane transporter activity MGI_ref:3849744|PMID:10942769 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) enables GO:0015093 ferrous iron transmembrane transporter activity MGI_ref:2664452|PMID:12522007 IDA NCBITaxon:10090 MGI:1345279 20090708 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) enables GO:0015093 ferrous iron transmembrane transporter activity MGI_ref:3849744|PMID:10942769 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0005886 plasma membrane MGI_ref:3691553|PMID:11739192 IDA NCBITaxon:10090 MGI:1345279 20090715 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0005886 plasma membrane MGI_ref:3695780|PMID:16905747 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0005886 plasma membrane MGI_ref:3849744|PMID:10942769 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0009986 cell surface MGI_ref:3695635|PMID:17097837 IDA NCBITaxon:10090 MGI:1345279 20090715 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0055037 recycling endosome MGI_ref:3691553|PMID:11739192 IDA NCBITaxon:10090 MGI:1345279 20090715 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) located_in GO:0055037 recycling endosome MGI_ref:3695780|PMID:16905747 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:0006824 cobalt ion transport MGI_ref:2664452|PMID:12522007 IDA NCBITaxon:10090 MGI:1345279 20090708 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:0006824 cobalt ion transport MGI_ref:3695780|PMID:16905747 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:0006824 cobalt ion transport MGI_ref:3849744|PMID:10942769 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:0006826 iron ion transport MGI_ref:2664452|PMID:12522007 IDA NCBITaxon:10090 MGI:1345279 20090708 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:0006826 iron ion transport MGI_ref:3849744|PMID:10942769 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse) mSLC11A2/iso:2|natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse) acts_upstream_of_or_within GO:1902600 proton transmembrane transport MGI_ref:3037617|PMID:15024413 IDA NCBITaxon:10090 MGI:1345279 20090716 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) enables GO:0005381 iron ion transmembrane transporter activity MGI_ref:3603092|PMID:16142913 IDA NCBITaxon:10090 MGI:1345279 20090706 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) enables GO:0015087 cobalt ion transmembrane transporter activity MGI_ref:3603092|PMID:16142913 IDA NCBITaxon:10090 MGI:1345279 20090706 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) enables GO:0015093 ferrous iron transmembrane transporter activity MGI_ref:3037617|PMID:15024413 IDA NCBITaxon:10090 MGI:1345279 20090716 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) located_in GO:0005769 early endosome MGI_ref:2667558|PMID:12724326 IDA NCBITaxon:10090 MGI:1345279 20080312 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) located_in GO:0005886 plasma membrane MGI_ref:2667558|PMID:12724326 IDA NCBITaxon:10090 MGI:1345279 20080311 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) located_in GO:0005903 brush border MGI_ref:3619154|PMID:11090085 IDA NCBITaxon:10090 MGI:1345279 20090716 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) located_in GO:0005903 brush border MGI_ref:3619154|PMID:11090085 IDA NCBITaxon:10090 UniProtKB:P49282-2 20090717 PRO:HJD PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) located_in GO:0012505 endomembrane system MGI_ref:2667558|PMID:12724326 IDA NCBITaxon:10090 MGI:1345279 20080311 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) acts_upstream_of_or_within GO:0006824 cobalt ion transport MGI_ref:3603092|PMID:16142913 IDA NCBITaxon:10090 MGI:1345279 20090707 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) acts_upstream_of_or_within GO:0006826 iron ion transport MGI_ref:3603092|PMID:16142913 IDA NCBITaxon:10090 MGI:1345279 20080311 MGI:MGI PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse) mSLC11A2/iso:1|natural resistance-associated macrophage protein 2 isoform IRE (mouse) acts_upstream_of_or_within GO:0033212 iron import into cell MGI_ref:3037617|PMID:15024413 IDA NCBITaxon:10090 MGI:1345279 20090716 MGI:MGI PR:P49450 histone H3-like centromeric protein A (human) CENP-A (human)|CENPA|centromere autoantigen A (human)|centromere protein A (human)|hCENPA enables GO:0005515 protein binding PR:P68431 BioGRID:BG-251005 IPI NCBITaxon:9606 UniProtKB:P49450 20130102 PRO:KER PR:P49450 histone H3-like centromeric protein A (human) CENP-A (human)|CENPA|centromere autoantigen A (human)|centromere protein A (human)|hCENPA enables GO:0005515 protein binding PR:Q96GD4 BioGRID:BG-608929 IPI NCBITaxon:9606 UniProtKB:P49450 20130102 PRO:KER PR:P49450 histone H3-like centromeric protein A (human) CENP-A (human)|CENPA|centromere autoantigen A (human)|centromere protein A (human)|hCENPA located_in GO:0000776 kinetochore PMID:15592459 EXP NCBITaxon:9606 UniProtKB:P49450 20121023 PRO:KER PR:P49454 centromere protein F (human) AH antigen (human)|CENP-F (human)|CENPF|hCENPF|kinetochore protein CENPF (human)|mitosin (human) enables GO:0005515 protein binding PR:Q02224 IntAct:EBI-1375056 IPI NCBITaxon:9606 UniProtKB:P49454 20130102 PRO:KER PR:P49454 centromere protein F (human) AH antigen (human)|CENP-F (human)|CENPF|hCENPF|kinetochore protein CENPF (human)|mitosin (human) located_in GO:0000776 kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:P49454 20130102 PRO:KER PR:P49747-1 cartilage oligomeric matrix protein isoform 1 (human) hCOMP/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:7670472 IDA NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:P49747-1 cartilage oligomeric matrix protein isoform 1 (human) hCOMP/iso:1 acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:7713493 IDA NCBITaxon:9606 UniProtKB:P49747-1 20080301 PRO:CNA PR:P49766-2 vascular endothelial growth factor B isoform VEGF-B167 (mouse) mVEGFB/iso:VEGF-B167 enables GO:0005515 protein binding PR:P97333 PMID:10409677 IPI NCBITaxon:10090 UniProtKB:P49766-2 20090717 PRO:CNA PR:P49772-1 fms-related tyrosine kinase 3 ligand isoform 1 (mouse) FLT3LG isoform 6C (mouse)|mFLT3LG/iso:1 enables GO:0030971 receptor tyrosine kinase binding PR:Q00342 MGI_ref:83693|PMID:8896402 IPI NCBITaxon:10090 MGI:95560 20081209 MGI:MGI PR:P49772-1 fms-related tyrosine kinase 3 ligand isoform 1 (mouse) FLT3LG isoform 6C (mouse)|mFLT3LG/iso:1 located_in GO:0009897 external side of plasma membrane MGI_ref:83693|PMID:8896402 IDA NCBITaxon:10090 MGI:95560 20090814 MGI:MGI PR:P49772-2 fms-related tyrosine kinase 3 ligand isoform 2 (mouse) FLT3LG isoform 5H (mouse)|mFLT3LG/iso:2 enables GO:0030971 receptor tyrosine kinase binding PR:Q00342 MGI_ref:83693|PMID:8896402 IPI NCBITaxon:10090 MGI:95560 20120111 MGI:MGI PR:P49772-2 fms-related tyrosine kinase 3 ligand isoform 2 (mouse) FLT3LG isoform 5H (mouse)|mFLT3LG/iso:2 located_in GO:0009897 external side of plasma membrane MGI_ref:83693|PMID:8896402 IDA NCBITaxon:10090 MGI:95560 20120111 MGI:MGI PR:P49772-3 fms-related tyrosine kinase 3 ligand isoform 3 (mouse) FLT3LG isoform E6 (mouse)|mFLT3LG/iso:3 enables GO:0030971 receptor tyrosine kinase binding PR:Q00342 MGI_ref:83693|PMID:8896402 IPI NCBITaxon:10090 MGI:95560 20120111 MGI:MGI PR:P49772-3 fms-related tyrosine kinase 3 ligand isoform 3 (mouse) FLT3LG isoform E6 (mouse)|mFLT3LG/iso:3 enables GO:0042803 protein homodimerization activity PR:P49772 MGI_ref:83693|PMID:8896402 IPI NCBITaxon:10090 MGI:95560 20081209 MGI:MGI PR:P49772-3 fms-related tyrosine kinase 3 ligand isoform 3 (mouse) FLT3LG isoform E6 (mouse)|mFLT3LG/iso:3 located_in GO:0005615 extracellular space MGI_ref:83693|PMID:8896402 IDA NCBITaxon:10090 MGI:95560 20090326 MGI:MGI PR:P51587 breast cancer type 2 susceptibility protein (human) BRCA2|FACD|FANCD1|Fanconi anemia group D1 protein (human)|hBRCA2 enables GO:0005515 protein binding PR:O60566 PMID:10749118 IPI NCBITaxon:9606 UniProtKB:P51587 20121112 PRO:KER PR:P51587 breast cancer type 2 susceptibility protein (human) BRCA2|FACD|FANCD1|Fanconi anemia group D1 protein (human)|hBRCA2 located_in GO:0005634 nucleus PMID:10749118 EXP NCBITaxon:9606 UniProtKB:P51587 20121112 PRO:KER PR:P51617-1 interleukin-1 receptor-associated kinase 1 isoform 1 (human) hIRAK1/iso:1|interleukin-1 receptor-associated kinase 1 isoform a (human) enables GO:0005515 protein binding PR:Q99836 PMID:14625308 IPI NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:P51617-1 interleukin-1 receptor-associated kinase 1 isoform 1 (human) hIRAK1/iso:1|interleukin-1 receptor-associated kinase 1 isoform a (human) enables GO:0005515 protein binding PR:Q9Y4K3 PMID:14625308 IPI NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:P51617-1 interleukin-1 receptor-associated kinase 1 isoform 1 (human) hIRAK1/iso:1|interleukin-1 receptor-associated kinase 1 isoform a (human) acts_upstream_of_or_within GO:0070498 interleukin-1-mediated signaling pathway PMID:14625308 EXP NCBITaxon:9606 UniProtKB:P51617-1 20100208 PRO:CNA PR:P51787-1 potassium voltage-gated channel subfamily KQT member 1 isoform 1 (human) hKCNQ1/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9312006 IDA NCBITaxon:9606 UniProtKB:P51787-1 20080601 PRO:CNA PR:P51787-2 potassium voltage-gated channel subfamily KQT member 1 isoform 2 (human) hKCNQ1/iso:2|potassium voltage-gated channel subfamily KQT member 1 isoform TKvLQT1 (human) contributes_to enables GO:0043267 negative regulation of potassium ion transport PMID:9305853 IDA NCBITaxon:9606 UniProtKB:P51787-2 20080601 PRO:CNA PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) enables GO:0004672 protein kinase activity PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) enables GO:0005515 protein binding PR:O14641 PMID:20823832 IPI NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER Timing=Mitosis. PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) enables GO:0005515 protein binding PR:O43683 BioGRID:BG-718371 IPI NCBITaxon:9606 UniProtKB:P53350 20130103 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) enables GO:0005515 protein binding PR:O60566 PMID:17376779 IPI NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) enables GO:0005515 protein binding PR:Q5FBB7 BioGRID:BG-338598 IPI NCBITaxon:9606 UniProtKB:P53350 20130103 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER Timing=Mitosis and spindle disruption (nocodazole). Localization increased by PR:000035412 and PR:Q9NQS7. PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) located_in GO:0000922 spindle pole PMID:20823832 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) located_in GO:0000940 outer kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) located_in GO:0005813 centrosome PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:17376779 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) acts_upstream_of_or_within GO:0034092 negative regulation of maintenance of sister chromatid cohesion PMID:16580887 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER Target=PR:Q13257. PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:17376779 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) NOT acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER Target=PR:O43683. PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1|PLK|PLK-1 (human)|PLK1|Polo-like kinase 1 (human)|serine/threonine-protein kinase 13 (human)|STPK13 (human) NOT acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:P53350 20121105 PRO:KER Target=PR:O60566. PR:P54199 serine/threonine-protein kinase MPS1 (yeast) D2785|monopolar spindle protein 1 (yeast)|MPS1|regulatory cell proliferation kinase 1 (yeast)|RPK1|YDL028C|yTTK enables GO:0004672 protein kinase activity PMID:22521787|PMID:8688079 EXP NCBITaxon:4932 UniProtKB:P54199 20121121 PRO:KER PR:P54199 serine/threonine-protein kinase MPS1 (yeast) D2785|monopolar spindle protein 1 (yeast)|MPS1|regulatory cell proliferation kinase 1 (yeast)|RPK1|YDL028C|yTTK acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:8688079 EXP NCBITaxon:4932 UniProtKB:P54199 20121121 PRO:KER PR:P54199 serine/threonine-protein kinase MPS1 (yeast) D2785|monopolar spindle protein 1 (yeast)|MPS1|regulatory cell proliferation kinase 1 (yeast)|RPK1|YDL028C|yTTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P54199 20121121 PRO:KER Target=PR:P26449. PR:P54199 serine/threonine-protein kinase MPS1 (yeast) D2785|monopolar spindle protein 1 (yeast)|MPS1|regulatory cell proliferation kinase 1 (yeast)|RPK1|YDL028C|yTTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22521787 EXP NCBITaxon:4932 UniProtKB:P54199 20121121 PRO:KER Target=PR:P41695. PR:P55014-1 solute carrier family 12 member 1 isoform A (mouse) mSlc12a1/iso:A acts_upstream_of_or_within GO:0070886 positive regulation of calcineurin-NFAT signaling cascade MGI_ref:4947009|PMID:21228109 IMP NCBITaxon:10090 MGI:103150 20150330 MGI:MGI occurs_in(CL:1001108) PR:P55014-1 solute carrier family 12 member 1 isoform A (mouse) mSlc12a1/iso:A acts_upstream_of_or_within GO:0071475 cellular hyperosmotic salinity response MGI_ref:4947009|PMID:21228109 IMP NCBITaxon:10090 MGI:103150 20150330 MGI:MGI occurs_in(CL:1001108) PR:P55014-4 solute carrier family 12 member 1 isoform F (mouse) mSlc12a1/iso:F|solute carrier family 12 member 1 isoform C9 (mouse) enables GO:0005515 protein binding PR:000044370|PR:G1JLS7|PR:Q9Z1W9-1 MGI_ref:5538439|PMID:24133122 IPI NCBITaxon:10090 MGI:103150 20141009 MGI:MGI PR:P55014-4 solute carrier family 12 member 1 isoform F (mouse) mSlc12a1/iso:F|solute carrier family 12 member 1 isoform C9 (mouse) enables GO:0008511 sodium:potassium:chloride symporter activity MGI_ref:5538439|PMID:24133122 IDA NCBITaxon:10090 MGI:103150 20141009 MGI:MGI PR:P55105-1 bone morphogenetic protein 8B isoform 1 (mouse) mBMP8B/iso:1 acts_upstream_of_or_within GO:0007283 spermatogenesis PMID:8682296|PMID:9463357 IDA NCBITaxon:10090 UniProtKB:P55105-1 20080301 PRO:CNA PR:P55105-1 bone morphogenetic protein 8B isoform 1 (mouse) mBMP8B/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:11427739 IDA NCBITaxon:10090 UniProtKB:P55105-1 20080301 PRO:CNA PR:P58390-1 small conductance calcium-activated potassium channel protein 2 isoform 1 (mouse) mKCNN2/iso:1 enables GO:0005216 monoatomic ion channel activity MGI_ref:3810884|PMID:18624921 IDA NCBITaxon:10090 MGI:2153182 20121024 MGI:MGI PR:P58390-1 small conductance calcium-activated potassium channel protein 2 isoform 1 (mouse) mKCNN2/iso:1 acts_upstream_of_or_within GO:0006811 monoatomic ion transport MGI_ref:3810884|PMID:18624921 IDA NCBITaxon:10090 MGI:2153182 20121024 MGI:MGI PR:P58753-2 Toll/interleukin-1 receptor domain-containing adapter protein isoform 2 (human) hTIRAP/iso:2 enables GO:0005546 phosphatidylinositol-4,5-bisphosphate binding PMID:24529375 EXP NCBITaxon:9606 UniProtKB:P58753-2 20140513 PRO:CNA PR:P60202-2 myelin proteolipid protein isoform DM-20 (mouse) mPLP1/iso:DM-20 acts_upstream_of_or_within GO:0048469 cell maturation MGI_ref:3614301|PMID:11746780 IMP NCBITaxon:10090 MGI:97623 20080811 MGI:MGI occurs_in(MA:0001097),results_in_maturation_of(CL:0000128) PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:1927281|PMID:11069937 IDA NCBITaxon:10090 MGI:94924 20070727 MGI:MGI occurs_in(MA:0000891) PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:3611062|PMID:12476322 IDA NCBITaxon:10090 MGI:94924 20070723 MGI:MGI occurs_in(MA:0000891) PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768|PMID:1991517 IDA NCBITaxon:10090 MGI:94924 20070717 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:893272|PMID:7706278 IDA NCBITaxon:10090 MGI:94924 20070719 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 located_in GO:0016020 membrane MGI_ref:893272|PMID:7706278 IDA NCBITaxon:10090 MGI:95751 MGI:94924 20070719 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway MGI_ref:893272|PMID:7706278 IGI NCBITaxon:10090 MGI:95772 MGI:94924 20070719 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway MGI_ref:893272|PMID:7706278 IMP NCBITaxon:10090 MGI:94924 20070723 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0007212 dopamine receptor signaling pathway MGI_ref:2181304|PMID:11089973 IGI NCBITaxon:10090 MGI:99578 MGI:94924 20070726 MGI:MGI occurs_in(MA:0000891) PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0007626 locomotory behavior MGI_ref:1927281|PMID:11069937 IMP NCBITaxon:10090 MGI:893591 MGI:94924 20070727 MGI:MGI PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0032228 regulation of synaptic transmission, GABAergic MGI_ref:3628700|PMID:15489038 IMP NCBITaxon:10090 MGI_allele:2387895|MGI_allele:2675755 MGI:94924 20070723 MGI:MGI regulates_o_occurs_in(MA:0000891) PR:P61168-1 D(2) dopamine receptor isoform 1 (mouse) D2A (mouse)|mDRD2/iso:1 acts_upstream_of_or_within GO:0060134 prepulse inhibition MGI_ref:3611062|PMID:12476322 IMP NCBITaxon:10090 MGI_allele:2656648 MGI:94924 20070723 MGI:MGI PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:3611062|PMID:12476322 IDA NCBITaxon:10090 MGI:94924 20140926 MGI:MGI occurs_in(MA:0000891) PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 enables GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768|PMID:1991517 IDA NCBITaxon:10090 MGI:94924 20140402 MGI:MGI PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0001975 response to amphetamine MGI_ref:3611062|PMID:12476322 IMP NCBITaxon:10090 MGI_allele:2656648 MGI:94924 20070723 MGI:MGI PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0014059 regulation of dopamine secretion MGI_ref:3655899|PMID:11943831 IMP NCBITaxon:10090 MGI_allele:2387895|MGI_allele:2675755 MGI:94924 20070723 MGI:MGI regulates_o_occurs_in(MA:0000891) PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0032228 regulation of synaptic transmission, GABAergic MGI_ref:3628700|PMID:15489038 IMP NCBITaxon:10090 MGI_allele:2387895|MGI_allele:2675755 MGI:94924 20140926 MGI:MGI regulates_o_occurs_in(MA:0000891) PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0042220 response to cocaine MGI_ref:3655899|PMID:11943831 IMP NCBITaxon:10090 MGI_allele:2387895 MGI:94924 20070723 MGI:MGI PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0043278 response to morphine MGI_ref:3655899|PMID:11943831 IMP NCBITaxon:10090 MGI_allele:2387895 MGI:94924 20070723 MGI:MGI PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0051967 negative regulation of synaptic transmission, glutamatergic MGI_ref:3628700|PMID:15489038 IMP NCBITaxon:10090 MGI_allele:2387895|MGI_allele:2675755 MGI:94924 20070723 MGI:MGI regulates_o_has_participant(MA:0000891) PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse) D2B (mouse)|mDRD2/iso:2 acts_upstream_of_or_within GO:0060160 negative regulation of dopamine receptor signaling pathway MGI_ref:2181304|PMID:11089973 IMP NCBITaxon:10090 MGI_allele:2675755 MGI:94924 20070726 MGI:MGI regulates_o_occurs_in(MA:0000891) PR:P61769-1 beta-2-microglobulin isoform 1 (human) hB2M/iso:1 has_role CHEBI:59163 biomarker PMID:17968930 EXP NCBITaxon:9606 UniProtKB:P61769-1 20100525 SALO:AJ PR:P61812-1 transforming growth factor beta-2 isoform A (human) hTGFB2/iso:A|TGFB2 isoform 1 (human) enables GO:0046982 protein heterodimerization activity PMID:2119582 IDA NCBITaxon:9606 UniProtKB:P61812-1 20080301 PRO:CNA PR:P61812-2 transforming growth factor beta-2 isoform B (human) hTGFB2/iso:B enables GO:0046982 protein heterodimerization activity PMID:17845732 TAS NCBITaxon:9606 UniProtKB:P61812-2 20080301 PRO:CNA PR:P61812-2 transforming growth factor beta-2 isoform B (human) hTGFB2/iso:B located_in GO:0045177 apical part of cell PMID:17845732 IDA NCBITaxon:9606 UniProtKB:P61812-2 20080301 PRO:CNA PR:P62258-1 14-3-3 protein epsilon isoform 1 (human) hYWHAE/iso:1 enables GO:0005515 protein binding PR:000026133 PMID:10949026 IPI NCBITaxon:9606 UniProtKB:P62258-1 20090709 PRO:JAN Note=binding between proteins from heterogeneous species PR:P62258-1 14-3-3 protein epsilon isoform 1 (human) hYWHAE/iso:1 enables GO:0005515 protein binding PR:000026167 PMID:10949026 IPI NCBITaxon:9606 UniProtKB:P62258-1 20090709 PRO:JAN Note=binding between proteins from heterogeneous species PR:P62500-2 TSC22 domain family protein 1 isoform 2 (mouse) mTSC22D1/iso:2 acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process MGI_ref:4940967|PMID:19745830 IDA NCBITaxon:10090 MGI:109127 20110412 MGI:MGI PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 enables GO:0005515 protein binding PR:Q13616-1 PMID:11961546 IPI NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 enables GO:0005515 protein binding PR:Q9EQW6 PMID:11027288 IPI NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 part_of GO:0000151 ubiquitin ligase complex PMID:16325183 IDA NCBITaxon:9606 UniProtKB:Q93034-1|UniProtKB:Q96Q27-1 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 part_of GO:0000151 ubiquitin ligase complex PMID:17217622 TAS NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 part_of GO:0019005 SCF ubiquitin ligase complex PMID:15966899 IDA NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 part_of GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899 IDA NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407 IDA NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 acts_upstream_of_or_within GO:0006606 protein import into nucleus PMID:11027288 IDA NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62877-1 E3 ubiquitin-protein ligase RBX1 isoform 1 (human) hRBX1/iso:1 acts_upstream_of_or_within GO:0045116 protein neddylation PMID:15966899 IDA NCBITaxon:9606 UniProtKB:P62877-1 20080301 PRO:CNA PR:P62881-1 guanine nucleotide-binding protein subunit beta-5 isoform 1 (mouse) guanine nucleotide-binding protein subunit beta-5 isoform Beta-5L (mouse)|guanine nucleotide-binding protein subunit beta-5 isoform Gbeta5L (mouse)|guanine nucleotide-binding protein subunit beta-5 isoform Long (mouse)|mGNB5/iso:1 located_in GO:0001750 photoreceptor outer segment MGI_ref:5507748|PMID:23555598 IDA NCBITaxon:10090 MGI:101848 20150108 MGI:MGI part_of(CL:0000604),happens_during(GO:0036367) PR:P62881-1 guanine nucleotide-binding protein subunit beta-5 isoform 1 (mouse) guanine nucleotide-binding protein subunit beta-5 isoform Beta-5L (mouse)|guanine nucleotide-binding protein subunit beta-5 isoform Gbeta5L (mouse)|guanine nucleotide-binding protein subunit beta-5 isoform Long (mouse)|mGNB5/iso:1 located_in GO:0001917 photoreceptor inner segment MGI_ref:5507748|PMID:23555598 IDA NCBITaxon:10090 MGI:101848 20150108 MGI:MGI part_of(CL:0000604),happens_during(GO:1990603) PR:P63015-1 paired box protein Pax-6 isoform 1 (mouse) mPAX6/iso:1|Pax-6 p46 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4867351|PMID:21084637 IDA NCBITaxon:10090 MGI:97490 20140122 MGI:MGI has_direct_input(MGI:88516) PR:P63016-1 paired box protein Pax-6 isoform 1 (rat) rPAX6/iso:1 located_in GO:0005634 nucleus PMID:24952136 IDA NCBITaxon:10116 UniProtKB:P63016-1 20140820 PRO:CNA PR:P63016-2 paired box protein Pax-6 isoform 2 (rat) rPAX6/iso:2 located_in GO:0005634 nucleus PMID:24952136 IDA NCBITaxon:10116 UniProtKB:P63016-2 20140820 PRO:CNA PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0001502 cartilage condensation PMID:9250685 IMP NCBITaxon:10090 MGI_allele:1860442 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0001503 ossification PMID:9250685 IMP NCBITaxon:10090 MGI_allele:1860442 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0001503 ossification PMID:9927422 IMP NCBITaxon:10090 MGI_allele:1860407 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0007611 learning or memory PMID:17129617 IMP NCBITaxon:10090 MGI_allele:1860442 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0008016 regulation of heart contraction PMID:15240882 IMP NCBITaxon:10090 MGI_allele:2183135 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0008016 regulation of heart contraction PMID:9430637 IMP NCBITaxon:10090 MGI_allele:1860441 UniProtKB:P63058 20091112 PRO:HJD PR:P63058 thyroid hormone receptor alpha (mouse) c-erbA-1 (mouse)|C-erba-alpha|c-erbA-alpha (mouse)|mTHRA|Nr1a1|nuclear receptor subfamily 1 group A member 1 (mouse)|Thra acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:9927422 IMP NCBITaxon:10090 MGI_allele:1860407 UniProtKB:P63058 20091112 PRO:HJD PR:P63058-1 thyroid hormone receptor alpha isoform Alpha-2 (mouse) mTHRA/iso:Alpha-2 enables GO:0005515 protein binding PR:Q61645 PMID:11641275 IPI NCBITaxon:10090 UniProtKB:P63058-1 20100215 PRO:HJD PR:P63058-1 thyroid hormone receptor alpha isoform Alpha-2 (mouse) mTHRA/iso:Alpha-2 enables GO:0005515 protein binding PR:Q924W6 PMID:15322135 IPI NCBITaxon:10090 UniProtKB:P63058-1 20100215 PRO:HJD PR:P63058-1 thyroid hormone receptor alpha isoform Alpha-2 (mouse) mTHRA/iso:Alpha-2 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:11641275|PMID:15062575 IDA NCBITaxon:10090 UniProtKB:P63058-1 20100215 PRO:HJD PR:P63058-2 thyroid hormone receptor alpha isoform Alpha-1 (mouse) mTHRA/iso:Alpha-1 enables GO:0002153 steroid receptor RNA activator RNA binding MGI_ref:3050934|PMID:15180993 IDA NCBITaxon:10090 MGI:98742 20091118 MGI:MGI PR:P63058-2 thyroid hormone receptor alpha isoform Alpha-1 (mouse) mTHRA/iso:Alpha-1 enables GO:0003727 single-stranded RNA binding MGI_ref:3050934|PMID:15180993 IDA NCBITaxon:10090 MGI:98742 20091113 MGI:MGI PR:P63058-4 thyroid hormone receptor alpha isoform Alpha-deltaE6 (mouse) mTHRA/iso:Alpha-deltaE6 located_in GO:0005737 cytoplasm MGI_ref:3619869|PMID:16322094 IDA NCBITaxon:10090 MGI:98742 20091210 MGI:MGI PR:P63058-4 thyroid hormone receptor alpha isoform Alpha-deltaE6 (mouse) mTHRA/iso:Alpha-deltaE6 acts_upstream_of_or_within GO:0010831 positive regulation of myotube differentiation MGI_ref:3619869|PMID:16322094 IDA NCBITaxon:10090 MGI:98742 20091210 MGI:MGI PR:P63058-4 thyroid hormone receptor alpha isoform Alpha-deltaE6 (mouse) mTHRA/iso:Alpha-deltaE6 acts_upstream_of_or_within GO:0042994 cytoplasmic sequestering of transcription factor MGI_ref:3619869|PMID:16322094 IDA NCBITaxon:10090 MGI:98742 20091210 MGI:MGI PR:P63085-1 mitogen-activated protein kinase 1 isoform 1 (mouse) mMAPK1/iso:1 located_in GO:0005737 cytoplasm PMID:11726647|PMID:12223545 IDA NCBITaxon:10090 UniProtKB:P63085-1 20080301 PRO:CNA PR:P63104 14-3-3 protein zeta/delta (human) hYWHAZ|KCIP-1 (human)|protein kinase C inhibitor protein 1 (human)|YWHAZ enables GO:0005515 protein binding PR:000044814 PMID:10477722 IPI NCBITaxon:9606 UniProtKB:P63104 20150504 PRO:CNA PR:P63142-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (rat) rKCNA2/iso:1 enables GO:0005515 protein binding PR:P78352 PMID:17959782 IPI NCBITaxon:10116 UniProtKB:P63142-1 20080601 PRO:CNA Note=Binding to DLG4 from different organism PR:P63208-1 S-phase kinase-associated protein 1 isoform 1 (human) hSKP1/iso:1 enables GO:0005515 protein binding PR:Q13616-1 PMID:12609982 IPI NCBITaxon:9606 UniProtKB:P63208-1 20080301 PRO:CNA PR:P63208-1 S-phase kinase-associated protein 1 isoform 1 (human) hSKP1/iso:1 part_of GO:0019005 SCF ubiquitin ligase complex PMID:11961546|PMID:12481031|PMID:16797541|PMID:17098746 IDA NCBITaxon:9606 UniProtKB:P63208-1 20080301 PRO:CNA PR:P63284-1 chaperone protein ClpB isoform 1 (Escherichia coli K-12) chaperone protein ClpB isoform ClpB (Escherichia coli K-12)|clpB isoform ClpB (Escherichia coli K-12)|Ec-clpB/iso:1 enables GO:0042802 identical protein binding PMID:8376377 EXP NCBITaxon:83333 UniProtKB:P63284-1 20100331 PRO:CNA PR:P63284-1 chaperone protein ClpB isoform 1 (Escherichia coli K-12) chaperone protein ClpB isoform ClpB (Escherichia coli K-12)|clpB isoform ClpB (Escherichia coli K-12)|Ec-clpB/iso:1 located_in GO:0005829 cytosol PMID:8376377 EXP NCBITaxon:83333 UniProtKB:P63284-1 20100331 PRO:CNA PR:P63284-2 chaperone protein ClpB isoform 2 (Escherichia coli K-12) chaperone protein ClpB isoform ClpB-3 (Escherichia coli K-12)|clpB isoform ClpB-3 (Escherichia coli K-12)|Ec-clpB/iso:2 located_in GO:0005829 cytosol PMID:8376377 EXP NCBITaxon:83333 UniProtKB:P63284-2 20100331 PRO:CNA PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse) calcium transport protein 2 (mouse)|CaT2 (mouse)|ECaC1 (mouse)|epithelial calcium channel 1 (mouse)|mTRPV5|Osm-9-like TRP channel 3 (mouse)|OTRPC3 (mouse)|Trpv5|TrpV5 (mouse) enables GO:0005262 calcium channel activity PMID:15665527 IDA NCBITaxon:10090 UniProtKB:P69744 20080601 PRO:CNA PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse) calcium transport protein 2 (mouse)|CaT2 (mouse)|ECaC1 (mouse)|epithelial calcium channel 1 (mouse)|mTRPV5|Osm-9-like TRP channel 3 (mouse)|OTRPC3 (mouse)|Trpv5|TrpV5 (mouse) enables GO:0005515 protein binding PMID:15355307 IPI NCBITaxon:10090 UniProtKB:P69744 20080601 PRO:CNA PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse) calcium transport protein 2 (mouse)|CaT2 (mouse)|ECaC1 (mouse)|epithelial calcium channel 1 (mouse)|mTRPV5|Osm-9-like TRP channel 3 (mouse)|OTRPC3 (mouse)|Trpv5|TrpV5 (mouse) located_in GO:0016324 apical plasma membrane PMID:12205031 IDA NCBITaxon:10090 UniProtKB:P69744 20080601 PRO:CNA PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse) calcium transport protein 2 (mouse)|CaT2 (mouse)|ECaC1 (mouse)|epithelial calcium channel 1 (mouse)|mTRPV5|Osm-9-like TRP channel 3 (mouse)|OTRPC3 (mouse)|Trpv5|TrpV5 (mouse) acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:15665527 IDA NCBITaxon:10090 UniProtKB:P69744 20080601 PRO:CNA PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse) calcium transport protein 2 (mouse)|CaT2 (mouse)|ECaC1 (mouse)|epithelial calcium channel 1 (mouse)|mTRPV5|Osm-9-like TRP channel 3 (mouse)|OTRPC3 (mouse)|Trpv5|TrpV5 (mouse) acts_upstream_of_or_within GO:0051262 protein tetramerization PMID:12574114 IDA NCBITaxon:10090 UniProtKB:P69744 20080601 PRO:CNA PR:P70160-1 calcitonin isoform 1 (mouse) mCALCA/iso:1 located_in GO:0005615 extracellular space MGI_ref:3028786|PMID:14765981 IDA NCBITaxon:10090 MGI:2151253 20110621 MGI:MGI part_of(MA:0000145) PR:P70160-1 calcitonin isoform 1 (mouse) mCALCA/iso:1 located_in GO:0005737 cytoplasm PMID:14765981 IDA NCBITaxon:10090 UniProtKB:P70160-1 20110617 PRO:HJD part_of(MA:0000792),part_of(CL:0000150)|part_of(MA:0000792),part_of(CL:0000167) PR:P70170-1 ATP-binding cassette sub-family C member 9 isoform 1 (mouse) mABCC9/iso:1|SUR2A (mouse) located_in GO:0042383 sarcolemma MGI_ref:4837999|PMID:20656890 IDA NCBITaxon:10090 MGI:1352630 20130327 MGI:MGI part_of(CL:0000746) PR:P70190 F-actin-capping protein subunit alpha-3 (mouse) Cappa3|CapZ alpha-3 (mouse)|CAPZA3|Capza3|germ cell-specific protein 3 (mouse)|Gsg3|mCAPZA3 acts_upstream_of_or_within GO:0007286 spermatid development MGI_ref:3848085|PMID:19341723 IMP NCBITaxon:10090 MGI_allele:3590195 MGI:106221 20130308 MGI:MGI occurs_in(CL:0000018),occurs_in(MA:0002765) PR:P70190 F-actin-capping protein subunit alpha-3 (mouse) Cappa3|CapZ alpha-3 (mouse)|CAPZA3|Capza3|germ cell-specific protein 3 (mouse)|Gsg3|mCAPZA3 colocalizes_with located_in GO:0001669 acrosomal vesicle MGI_ref:3848085|PMID:19341723 IDA NCBITaxon:10090 MGI:106221 20130308 MGI:MGI PR:P70336-2 Rho-associated protein kinase 2 isoform 2 (mouse) mROCK2/iso:2|rho-associated protein kinase 2 isoform ROCK2m (mouse) enables GO:0004674 protein serine/threonine kinase activity PMID:17606625 IDA NCBITaxon:10090 UniProtKB:P70336-2 20080301 PRO:CNA PR:P70336-2 Rho-associated protein kinase 2 isoform 2 (mouse) mROCK2/iso:2|rho-associated protein kinase 2 isoform ROCK2m (mouse) acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:17606625 IDA NCBITaxon:10090 UniProtKB:P70336-2 20080301 PRO:CNA PR:P70336-2 Rho-associated protein kinase 2 isoform 2 (mouse) mROCK2/iso:2|rho-associated protein kinase 2 isoform ROCK2m (mouse) acts_upstream_of_or_within GO:0051149 positive regulation of muscle cell differentiation PMID:17606625 IDA NCBITaxon:10090 UniProtKB:P70336-2 20080301 PRO:CNA PR:P70340-1 mothers against decapentaplegic homolog 1 isoform 1 (mouse) mSMAD1/iso:1 located_in GO:0005737 cytoplasm PMID:10504300|PMID:17356069 IDA NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:P70340-1 mothers against decapentaplegic homolog 1 isoform 1 (mouse) mSMAD1/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:15198985|PMID:15331632|PMID:17356069 IDA NCBITaxon:10090 UniProtKB:P70340-1 20080301 PRO:CNA PR:P70390-1 short stature homeobox protein 2 isoform 1 (mouse) mSHOX2/iso:1|short stature homeobox protein 2 isoform OG12A (mouse)|short stature homeobox protein 2 isoform PRX3A (mouse) acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3714677|PMID:17481601 IDA NCBITaxon:10090 MGI:1201673 20070808 MGI:MGI PR:P70390-1 short stature homeobox protein 2 isoform 1 (mouse) mSHOX2/iso:1|short stature homeobox protein 2 isoform OG12A (mouse)|short stature homeobox protein 2 isoform PRX3A (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3714677|PMID:17481601 IDA NCBITaxon:10090 MGI:1201673 20070808 MGI:MGI PR:P70390-2 short stature homeobox protein 2 isoform 2 (mouse) mSHOX2/iso:2|short stature homeobox protein 2 isoform OG12B (mouse)|short stature homeobox protein 2 isoform PRX3B (mouse) acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3714677|PMID:17481601 IDA NCBITaxon:10090 MGI:1201673 20140805 MGI:MGI PR:P70390-2 short stature homeobox protein 2 isoform 2 (mouse) mSHOX2/iso:2|short stature homeobox protein 2 isoform OG12B (mouse)|short stature homeobox protein 2 isoform PRX3B (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3714677|PMID:17481601 IDA NCBITaxon:10090 MGI:1201673 20140805 MGI:MGI PR:P70441-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse) mSLC9A3R1/iso:1 enables GO:0051219 phosphoprotein binding PR:000044790 PMID:15591354 IPI NCBITaxon:10090 UniProtKB:P70441-1 20090717 PRO:AL Note=Binds to phospho-ERM proteins PR:P70441-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse) mSLC9A3R1/iso:1 located_in GO:0031526 brush border membrane PMID:15591354 EXP NCBITaxon:10090 UniProtKB:P70441-1 20090717 PRO:AL PR:P70444-1 BH3-interacting domain death agonist isoform 1 (mouse) mBID/iso:1|p22 (mouse) located_in GO:0005737 cytoplasm MGI_ref:4940333|PMID:9873064 IDA NCBITaxon:10090 MGI:108093 20110316 MGI:MGI PR:P70444-1 BH3-interacting domain death agonist isoform 1 (mouse) mBID/iso:1|p22 (mouse) NOT located_in GO:0005739 mitochondrion PMID:9873064 IDA NCBITaxon:10090 UniProtKB:P70444-1 20110309 PRO:HJD PR:P70671-1 interferon regulatory factor 3 isoform 1 (mouse) mIRF3/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3828224|PMID:18851954 IDA NCBITaxon:10090 MGI:1859179 20101020 MGI:MGI PR:P76339-1 sensor-like histidine kinase YedV isoform 1 (Escherichia coli K-12) Ec-yedV/iso:1 enables GO:0004672 protein kinase activity EcoCyc:G7056-MONOMER EXP NCBITaxon:83333 UniProtKB:P76339-1 20100331 PRO:CNA PR:P76387-1 tyrosine-protein kinase wzc isoform 1 (Escherichia coli K-12) Ec-wzc/iso:1 enables GO:0004713 protein tyrosine kinase activity PMID:11751920 EXP NCBITaxon:83333 UniProtKB:P76387-1 20100331 PRO:CNA Target=PR:P76387-1. PR:P81183 zinc finger protein Helios (mouse) Helios|Ikaros family zinc finger protein 2 (mouse)|Ikzf2|mIKZF2|Zfpn1a2|Znfn1a2 enables GO:0042803 protein homodimerization activity PR:P81183 PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183 20090513 PRO:HJD PR:P81183 zinc finger protein Helios (mouse) Helios|Ikaros family zinc finger protein 2 (mouse)|Ikzf2|mIKZF2|Zfpn1a2|Znfn1a2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:9560339 IDA NCBITaxon:10090 UniProtKB:P81183 20090513 PRO:HJD PR:P81183-1 zinc finger protein Helios isoform B (mouse) mIKZF2/iso:B enables GO:0046982 protein heterodimerization activity PR:O08900 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-1 20090513 MGI:MGI PR:P81183-1 zinc finger protein Helios isoform B (mouse) mIKZF2/iso:B enables GO:0046982 protein heterodimerization activity PR:O08900-1|PR:Q03267-1 PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-1 20090513 PRO:HJD PR:P81183-1 zinc finger protein Helios isoform B (mouse) mIKZF2/iso:B enables GO:0046982 protein heterodimerization activity PR:Q03267-1 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-1 20090513 MGI:MGI PR:P81183-1 zinc finger protein Helios isoform B (mouse) mIKZF2/iso:B located_in GO:0005634 nucleus PMID:9560339 IDA NCBITaxon:10090 UniProtKB:P81183-1 20090513 PRO:HJD PR:P81183-2 zinc finger protein Helios isoform A (mouse) mIKZF2/iso:A enables GO:0046982 protein heterodimerization activity PR:O08900-1|PR:Q03267-1 PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-2 20090513 PRO:HJD PR:P81183-2 zinc finger protein Helios isoform A (mouse) mIKZF2/iso:A enables GO:0046982 protein heterodimerization activity PR:P81183-1 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-2 20111216 MGI:MGI PR:P81183-2 zinc finger protein Helios isoform A (mouse) mIKZF2/iso:A enables GO:0046982 protein heterodimerization activity PR:P81183-2 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 UniProtKB:P81183-2 20111216 MGI:MGI PR:P81183-2 zinc finger protein Helios isoform A (mouse) mIKZF2/iso:A located_in GO:0005634 nucleus PMID:9560339 IDA NCBITaxon:10090 UniProtKB:P81183-2 20090513 PRO:HJD PR:P84022-1 mothers against decapentaplegic homolog 3 isoform 1 (human) hSMAD3/iso:1 enables GO:0005515 protein binding PR:000025959 PMID:12154125 IPI NCBITaxon:9606 UniProtKB:P84022-1 20100930 PRO:CNA PR:P84022-1 mothers against decapentaplegic homolog 3 isoform 1 (human) hSMAD3/iso:1 enables GO:0005515 protein binding PR:O95405-1 PMID:12154125 IPI NCBITaxon:9606 UniProtKB:P84022-1 20100930 PRO:CNA PR:P84022-1 mothers against decapentaplegic homolog 3 isoform 1 (human) hSMAD3/iso:1 located_in GO:0005737 cytoplasm PMID:17074053 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:P84022-1 mothers against decapentaplegic homolog 3 isoform 1 (human) hSMAD3/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8774881 IDA NCBITaxon:9606 UniProtKB:P84022-1 20080301 PRO:CNA PR:P97287-1 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse) MCL-1L (mouse)|mMCL1/iso:1 located_in GO:0005739 mitochondrion MGI_ref:4421270|PMID:19919825 IDA NCBITaxon:10090 MGI:101769 20101006 MGI:MGI PR:P97287-1 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse) MCL-1L (mouse)|mMCL1/iso:1 acts_upstream_of_or_within GO:0008637 apoptotic mitochondrial changes MGI_ref:4421270|PMID:19919825 IDA NCBITaxon:10090 MGI:101769 20130621 MGI:MGI PR:P97287-2 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse) MCL-1V (mouse)|mMCL1/iso:2 located_in GO:0005739 mitochondrion MGI_ref:4421270|PMID:19919825 IDA NCBITaxon:10090 MGI:101769 20140502 MGI:MGI PR:P97287-2 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse) MCL-1V (mouse)|mMCL1/iso:2 acts_upstream_of_or_within GO:0008637 apoptotic mitochondrial changes MGI_ref:4421270|PMID:19919825 IDA NCBITaxon:10090 MGI:101769 20130621 MGI:MGI PR:P97333 neuropilin-1 (mouse) A5 protein (mouse)|CD304 (mouse)|mNRP1|Nrp|Nrp1 enables GO:0005515 protein binding PR:000036636 PMID:10409677 IPI NCBITaxon:10090 UniProtKB:P97333 20090717 PRO:JAN PR:P97333 neuropilin-1 (mouse) A5 protein (mouse)|CD304 (mouse)|mNRP1|Nrp|Nrp1 enables GO:0005515 protein binding PR:P49766-2 PMID:10409677 IPI NCBITaxon:10090 UniProtKB:P97333 20090717 PRO:JAN PR:P97363 serine palmitoyltransferase 2 (mouse) LCB 2 (mouse)|Lcb2|LCB2a (mouse)|long chain base biosynthesis protein 2 (mouse)|long chain base biosynthesis protein 2a (mouse)|mSPTLC2|serine-palmitoyl-CoA transferase 2 (mouse)|SPT 2 (mouse)|Sptlc2 acts_upstream_of_or_within GO:0006686 sphingomyelin biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815117 UniProtKB:P97363 20100215 PRO:HJD PR:P97363 serine palmitoyltransferase 2 (mouse) LCB 2 (mouse)|Lcb2|LCB2a (mouse)|long chain base biosynthesis protein 2 (mouse)|long chain base biosynthesis protein 2a (mouse)|mSPTLC2|serine-palmitoyl-CoA transferase 2 (mouse)|SPT 2 (mouse)|Sptlc2 acts_upstream_of_or_within GO:0046512 sphingosine biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815117 UniProtKB:P97363 20100215 PRO:HJD PR:P97363 serine palmitoyltransferase 2 (mouse) LCB 2 (mouse)|Lcb2|LCB2a (mouse)|long chain base biosynthesis protein 2 (mouse)|long chain base biosynthesis protein 2a (mouse)|mSPTLC2|serine-palmitoyl-CoA transferase 2 (mouse)|SPT 2 (mouse)|Sptlc2 acts_upstream_of_or_within GO:0046513 ceramide biosynthetic process PMID:16216550 IMP NCBITaxon:10090 MGI_allele:3815117 UniProtKB:P97363 20100215 PRO:HJD PR:P97363-1 serine palmitoyltransferase 2 isoform 1 (mouse) mSPTLC2/iso:1 enables GO:0004758 serine C-palmitoyltransferase activity PMID:9363775 IDA NCBITaxon:10090 UniProtKB:P97363-1 20100215 PRO:HJD PR:P97363-1 serine palmitoyltransferase 2 isoform 1 (mouse) mSPTLC2/iso:1 located_in GO:0005739 mitochondrion PMID:18614015 IDA NCBITaxon:10090 UniProtKB:P97363-1 20100215 PRO:HJD PR:P97363-1 serine palmitoyltransferase 2 isoform 1 (mouse) mSPTLC2/iso:1 acts_upstream_of_or_within GO:0046511 sphinganine biosynthetic process PMID:9363775 IDA NCBITaxon:10090 UniProtKB:P97363-1 20100215 PRO:HJD PR:P97367-1 homeobox protein Meis2 isoform Meis2C (mouse) mMEIS2/iso:Meis2C enables GO:0005515 protein binding PR:Q62424 MGI_ref:3527920|PMID:15617687 IPI NCBITaxon:10090 MGI:104717 20080829 MGI:MGI PR:P97367-2 homeobox protein Meis2 isoform Meis2A (mouse) mMEIS2/iso:Meis2A enables GO:0005515 protein binding PR:Q62424 MGI_ref:3527920|PMID:15617687 IPI NCBITaxon:10090 MGI:104717 20140502 MGI:MGI PR:P97386-1 DNA ligase 3 isoform Alpha (mouse) mLIG3/iso:Alpha enables GO:0005515 protein binding PR:P18887 MGI_ref:85057|PMID:9001252 IPI NCBITaxon:10090 MGI:109152 20120710 MGI:MGI PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse) mSMAD5/iso:1 located_in GO:0005737 cytoplasm PMID:10504300 IDA NCBITaxon:10090 UniProtKB:P97454-1 20080301 PRO:CNA PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse) mSMAD5/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:16765933 IDA NCBITaxon:10090 UniProtKB:P97454-1 20080301 PRO:CNA PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse) mSMAD5/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:16522160|PMID:16765933 IDA NCBITaxon:10090 UniProtKB:P97454-1 20080301 PRO:CNA PR:P97466-1 noggin isoform 1 (mouse) mNOG/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:15110716 IDA NCBITaxon:10090 UniProtKB:P97466-1 20080301 PRO:CNA PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 enables GO:0003700 DNA-binding transcription factor activity PMID:12943993|PMID:14633973|PMID:16522160|PMID:16556916 IDA NCBITaxon:10090 UniProtKB:P97471-1 20080301 PRO:CNA PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 located_in GO:0005634 nucleus PMID:12543979|PMID:12943993|PMID:16522160 IDA NCBITaxon:10090 UniProtKB:P97471-1 20080301 PRO:CNA PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 part_of GO:0005667 transcription factor complex PMID:14633973|PMID:9288972|PMID:9702197 IDA NCBITaxon:10090 UniProtKB:P97471-1 20080301 PRO:CNA PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17142805 IDA NCBITaxon:10090 UniProtKB:P97471-1 20080301 PRO:CNA PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:16522160 IDA NCBITaxon:10090 UniProtKB:P97471-1 20080301 PRO:CNA PR:P97474-1 pituitary homeobox 2 isoform Ptx2B (mouse) mPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (mouse)|pituitary homeobox 2 isoform BRX1B (mouse) part_of GO:0005667 transcription factor complex PMID:12464179|PMID:15385555 IDA NCBITaxon:10090 UniProtKB:P97474-1 20080301 PRO:CNA PR:P97474-1 pituitary homeobox 2 isoform Ptx2B (mouse) mPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (mouse)|pituitary homeobox 2 isoform BRX1B (mouse) acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:12397115 IDA NCBITaxon:10090 UniProtKB:P97474-1 20080301 PRO:CNA PR:P97474-1 pituitary homeobox 2 isoform Ptx2B (mouse) mPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (mouse)|pituitary homeobox 2 isoform BRX1B (mouse) acts_upstream_of_or_within GO:0016055 Wnt signaling pathway PMID:12464179 IDA NCBITaxon:10090 UniProtKB:P97474-1 20080301 PRO:CNA PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse) mPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (mouse)|pituitary homeobox 2 isoform BRX1A (mouse) acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10585561 IDA NCBITaxon:10090 UniProtKB:P97474-2 20080301 PRO:CNA PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse) mPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (mouse)|pituitary homeobox 2 isoform BRX1A (mouse) acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:9708732 IDA NCBITaxon:10090 UniProtKB:P97474-2 20080301 PRO:CNA PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse) mPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (mouse)|pituitary homeobox 2 isoform BRX1A (mouse) acts_upstream_of_or_within GO:0007520 myoblast fusion MGI_ref:3686567|PMID:16958127 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse) mPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (mouse)|pituitary homeobox 2 isoform BRX1A (mouse) acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:10585561 IDA NCBITaxon:10090 UniProtKB:P97474-2 20080301 PRO:CNA PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse) mPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (mouse)|pituitary homeobox 2 isoform BRX1A (mouse) acts_upstream_of_or_within GO:2000288 positive regulation of myoblast proliferation MGI_ref:3686567|PMID:16958127 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI_ref:3796777|PMID:18458156 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) enables GO:0003712 transcription coregulator activity MGI_ref:3796777|PMID:18458156 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) enables GO:0003677 DNA binding MGI_ref:3796777|PMID:18458156 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) enables GO:0005515 protein binding PR:Q9JM73 MGI_ref:3796777|PMID:18458156 IPI NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) enables GO:0008134 transcription factor binding PMID:15385555 IDA NCBITaxon:10090 UniProtKB:P97474-3 20080301 PRO:CNA PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) located_in GO:0005634 nucleus MGI_ref:3796777|PMID:18458156 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) located_in GO:0005634 nucleus PMID:11854422 IDA NCBITaxon:10090 UniProtKB:P97474-3 20080301 PRO:CNA PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PMID:11854422 IDA NCBITaxon:10090 UniProtKB:P97474-3 20080301 PRO:CNA PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:11854422 IDA NCBITaxon:10090 UniProtKB:P97474-3 20080301 PRO:CNA PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) acts_upstream_of_or_within GO:0043388 positive regulation of DNA binding MGI_ref:3796777|PMID:18458156 IDA NCBITaxon:10090 MGI:109340 20111024 MGI:MGI PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse) mPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (mouse) NOT acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:10585561 IDA NCBITaxon:10090 UniProtKB:P97474-3 20080301 PRO:CNA PR:P97807-1 fumarate hydratase, mitochondrial isoform 1 (mouse) fumarate hydratase isoform mitochondrial (mouse)|mFH/iso:1 located_in GO:0005739 mitochondrion MGI_ref:2682130|PMID:14651853 IDA NCBITaxon:10090 MGI:95530 20100629 MGI:MGI part_of(MA:0000358)|part_of(MA:0000168)|part_of(MA:0000368)|part_of(MA:0000072) PR:P97807-1 fumarate hydratase, mitochondrial isoform 1 (mouse) fumarate hydratase isoform mitochondrial (mouse)|mFH/iso:1 located_in GO:0005739 mitochondrion PMID:14651853|PMID:18614015 EXP NCBITaxon:10090 UniProtKB:P97807-1 20100629 PRO:CNA PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse) mMAP4K4/iso:1 enables GO:0004674 protein serine/threonine kinase activity PMID:16938849 EXP NCBITaxon:10090 UniProtKB:P97820-1 20090709 PRO:AL PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse) mMAP4K4/iso:1 enables GO:0005515 protein binding PR:O35763 PMID:16938849 IPI NCBITaxon:10090 UniProtKB:P97820-1 20090709 PRO:AL PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse) mMAP4K4/iso:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:16938849 EXP NCBITaxon:10090 UniProtKB:P97820-1 20090709 PRO:AL PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse) mMAP4K4/iso:1 acts_upstream_of_or_within GO:0010591 regulation of lamellipodium assembly PMID:16938849 EXP NCBITaxon:10090 UniProtKB:P97820-1 20090709 PRO:AL PR:P97953-1 vascular endothelial growth factor C isoform 1 (mouse) mVEGFC/iso:1 enables GO:0005515 protein binding PR:P09405 MGI_ref:4820931|PMID:20415667 IPI NCBITaxon:10090 MGI:109124 20130930 MGI:MGI PR:P97953-1 vascular endothelial growth factor C isoform 1 (mouse) mVEGFC/iso:1 acts_upstream_of_or_within GO:0001954 positive regulation of cell-matrix adhesion MGI_ref:4820931|PMID:20415667 IDA NCBITaxon:10090 MGI:109124 20130930 MGI:MGI regulates_o_has_participant(CL:0000653) PR:P97953-1 vascular endothelial growth factor C isoform 1 (mouse) mVEGFC/iso:1 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation MGI_ref:4820931|PMID:20415667 IDA NCBITaxon:10090 MGI:109124 20130930 MGI:MGI regulates_o_acts_on_population_of(CL:0000653) PR:P97953-1 vascular endothelial growth factor C isoform 1 (mouse) mVEGFC/iso:1 acts_upstream_of_or_within GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:4820931|PMID:20415667 IDA NCBITaxon:10090 MGI:109124 20130930 MGI:MGI PR:P98078-1 disabled homolog 2 isoform 1 (mouse) DAB2 p96 (mouse)|disabled homolog 2 isoform p96 (mouse)|mDAB2/iso:1 located_in GO:0005737 cytoplasm MGI_ref:1929027|PMID:11104669 IDA NCBITaxon:10090 MGI:109175 20091104 MGI:MGI PR:P98078-1 disabled homolog 2 isoform 1 (mouse) DAB2 p96 (mouse)|disabled homolog 2 isoform p96 (mouse)|mDAB2/iso:1 acts_upstream_of_or_within GO:0006907 pinocytosis MGI_ref:3610714|PMID:16263760 IMP NCBITaxon:10090 MGI_allele:2387168 MGI:109175 20080811 MGI:MGI occurs_in(EMAP:194),occurs_in(CL:0000223),has_participant(MGI:MGI:95794)|occurs_in(EMAP:194),occurs_in(CL:0000223),has_participant(MGI:MGI:1931256)|occurs_in(EMAP:194),occurs_in(CL:0000223),has_participant(MGI:MGI:2140175) PR:P98078-1 disabled homolog 2 isoform 1 (mouse) DAB2 p96 (mouse)|disabled homolog 2 isoform p96 (mouse)|mDAB2/iso:1 acts_upstream_of_or_within GO:0007492 endoderm development MGI_ref:5319713|PMID:22525672 IMP NCBITaxon:10090 MGI:109175 20120622 MGI:MGI has_participant(CL:0002322) PR:P98078-1 disabled homolog 2 isoform 1 (mouse) DAB2 p96 (mouse)|disabled homolog 2 isoform p96 (mouse)|mDAB2/iso:1 acts_upstream_of_or_within GO:0007492 endoderm development MGI_ref:5319713|PMID:22525672 IMP NCBITaxon:10090 UniProtKB:P98078-1 20120625 PRO:HJD PR:P98078-3 disabled homolog 2 isoform 3 (mouse) DAB2 p67 (mouse)|disabled homolog 2 isoform p67 (mouse)|mDAB2/iso:3 enables GO:0005515 protein binding PR:Q8C5D8-2 MGI_ref:1929027|PMID:11104669 IPI NCBITaxon:10090 MGI:109175 20091104 MGI:MGI PR:P98078-3 disabled homolog 2 isoform 3 (mouse) DAB2 p67 (mouse)|disabled homolog 2 isoform p67 (mouse)|mDAB2/iso:3 located_in GO:0005634 nucleus MGI_ref:1929027|PMID:11104669 IDA NCBITaxon:10090 MGI:109175 20091104 MGI:MGI PR:P98078-3 disabled homolog 2 isoform 3 (mouse) DAB2 p67 (mouse)|disabled homolog 2 isoform p67 (mouse)|mDAB2/iso:3 NOT acts_upstream_of_or_within GO:0007492 endoderm development MGI_ref:5319713|PMID:22525672 IMP NCBITaxon:10090 MGI:109175 20120622 MGI:MGI has_participant(CL:0002322) PR:P99999-1 cytochrome c isoform 1 (human) hCYCS/iso:1 enables GO:0005515 protein binding PR:O14727-3 PMID:9267021 IPI NCBITaxon:9606 UniProtKB:P99999-1 20090918 PRO:JAN PR:P99999-1 cytochrome c isoform 1 (human) hCYCS/iso:1 acts_upstream_of_or_within GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process PMID:9267021 EXP NCBITaxon:9606 UniProtKB:P99999-1 20090918 PRO:JAN PR:Q00194-1 cGMP-gated cation channel alpha-1 isoform 1 (cow) cow-CNGA1/iso:1 part_of GO:0017071 intracellular cyclic nucleotide activated cation channel complex PMID:12432397|PMID:12467591 IDA NCBITaxon:9913 UniProtKB:Q00194-1 20080601 PRO:CNA PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0005102 signaling receptor binding MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0005515 protein binding PR:P97333 MGI_ref:1860784|PMID:10705382 IPI NCBITaxon:10090 MGI:103178 20140227 MGI:MGI occurs_in(MA:0001722)|occurs_in(MA:0000386) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0008201 heparin binding MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0008201 heparin binding MGI_ref:77585|PMID:8614412 IDA NCBITaxon:10090 MGI:103178 20140226 MGI:MGI occurs_in(MA:0000127) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0043183 vascular endothelial growth factor receptor 1 binding MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0043184 vascular endothelial growth factor receptor 2 binding MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0043184 vascular endothelial growth factor receptor 2 binding PR:P35918 MGI_ref:1860784|PMID:10705382 IPI NCBITaxon:10090 MGI:103178 20140227 MGI:MGI occurs_in(MA:0001722)|occurs_in(MA:0000386) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) enables GO:0050840 extracellular matrix binding MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) located_in GO:0005576 extracellular region MGI_ref:77585|PMID:8614412 IDA NCBITaxon:10090 MGI:103178 20140226 MGI:MGI occurs_in(MA:0000127) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0001525 angiogenesis MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0001569 branching involved in blood vessel morphogenesis MGI_ref:3710026|PMID:17428830 IMP NCBITaxon:10090 MGI_allele:1931047 MGI:103178 20070802 MGI:MGI occurs_in(EMAP:4187)|occurs_in(EMAP:4011) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0001938 positive regulation of endothelial cell proliferation MGI_ref:74931|PMID:1592003 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI regulates_o_acts_on_population_of(CL:0000115) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0002053 positive regulation of mesenchymal cell proliferation MGI_ref:3613102|PMID:16375885 IDA NCBITaxon:10090 MGI:103178 20070803 MGI:MGI occurs_in(EMAP:34318),regulates_o_acts_on_population_of(CL:0000134) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0030324 lung development MGI_ref:3613102|PMID:16375885 IDA NCBITaxon:10090 MGI:103178 20070803 MGI:MGI occurs_in(EMAP:34278) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI_ref:74931|PMID:1592003 IDA NCBITaxon:10090 MGI:103178 20070807 MGI:MGI PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0048754 branching morphogenesis of an epithelial tube MGI_ref:3613102|PMID:16375885 IDA NCBITaxon:10090 MGI:103178 20070803 MGI:MGI occurs_in(EMAP:34278) PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse) mVEGFA/iso:2|VEGF-1 (mouse)|VEGF164 (mouse) acts_upstream_of_or_within GO:0060426 lung vasculature development MGI_ref:1927039|PMID:11066091 IDA NCBITaxon:10090 MGI:103178 20140325 MGI:MGI occurs_in(EMAP:4604) PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse) mVEGFA/iso:3|VEGF-2 (mouse)|VEGF120 (mouse) located_in GO:0005576 extracellular region MGI_ref:77585|PMID:8614412 IDA NCBITaxon:10090 MGI:103178 20140226 MGI:MGI occurs_in(MA:0000127) PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse) mVEGFA/iso:3|VEGF-2 (mouse)|VEGF120 (mouse) located_in GO:0005615 extracellular space MGI_ref:74931|PMID:1592003 IDA NCBITaxon:10090 MGI:103178 20070807 MGI:MGI PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse) mVEGFA/iso:3|VEGF-2 (mouse)|VEGF120 (mouse) acts_upstream_of_or_within GO:0001525 angiogenesis MGI_ref:3758404|PMID:17626017 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse) mVEGFA/iso:3|VEGF-2 (mouse)|VEGF120 (mouse) acts_upstream_of_or_within GO:0001938 positive regulation of endothelial cell proliferation MGI_ref:74931|PMID:1592003 IDA NCBITaxon:10090 MGI:103178 20070807 MGI:MGI regulates_o_acts_on_population_of(CL:0000115) PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse) mVEGFA/iso:3|VEGF-2 (mouse)|VEGF120 (mouse) acts_upstream_of_or_within GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI_ref:74931|PMID:1592003 IDA NCBITaxon:10090 MGI:103178 20140328 MGI:MGI PR:Q00731-4 vascular endothelial growth factor A, long form isoform 4 (mouse) mVEGFA/iso:4|VEGF-4 (mouse)|VEGF115 (mouse) enables GO:0008083 growth factor activity MGI_ref:1195544|PMID:9446618 IDA NCBITaxon:10090 MGI:103178 20140227 MGI:MGI PR:Q00731-4 vascular endothelial growth factor A, long form isoform 4 (mouse) mVEGFA/iso:4|VEGF-4 (mouse)|VEGF115 (mouse) located_in GO:0005576 extracellular region MGI_ref:1195544|PMID:9446618 IDA NCBITaxon:10090 MGI:103178 20140226 MGI:MGI PR:Q00731-4 vascular endothelial growth factor A, long form isoform 4 (mouse) mVEGFA/iso:4|VEGF-4 (mouse)|VEGF115 (mouse) acts_upstream_of_or_within GO:0001938 positive regulation of endothelial cell proliferation MGI_ref:1195544|PMID:9446618 IDA NCBITaxon:10090 MGI:103178 20140226 MGI:MGI PR:Q00941-1 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse) GM-CSF receptor alpha subunit isoform 1 (mouse)|GM-CSF receptor alpha-chain isoform 1 (mouse)|GMRalpha isoform 1 (mouse)|mCSF2RA/iso:1|muGM-CSFR clone 71 enables GO:0004902 granulocyte colony-stimulating factor receptor activity MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:Q00941-1 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse) GM-CSF receptor alpha subunit isoform 1 (mouse)|GM-CSF receptor alpha-chain isoform 1 (mouse)|GMRalpha isoform 1 (mouse)|mCSF2RA/iso:1|muGM-CSFR clone 71 enables GO:0051916 granulocyte colony-stimulating factor binding MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:Q00941-1 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse) GM-CSF receptor alpha subunit isoform 1 (mouse)|GM-CSF receptor alpha-chain isoform 1 (mouse)|GMRalpha isoform 1 (mouse)|mCSF2RA/iso:1|muGM-CSFR clone 71 located_in GO:0005886 plasma membrane MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:Q00941-1 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse) GM-CSF receptor alpha subunit isoform 1 (mouse)|GM-CSF receptor alpha-chain isoform 1 (mouse)|GMRalpha isoform 1 (mouse)|mCSF2RA/iso:1|muGM-CSFR clone 71 acts_upstream_of_or_within GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369|PMID:17694571 IDA NCBITaxon:10090 MGI:1339754 20150306 MGI:MGI PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) enables GO:0005515 protein binding PR:O60566 PMID:17785528 IPI NCBITaxon:9606 UniProtKB:Q02224 20121023 PRO:KER PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) enables GO:0005515 protein binding PR:P49454 IntAct:EBI-1375056 IPI NCBITaxon:9606 UniProtKB:Q02224 20130103 PRO:KER PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) enables GO:0005515 protein binding PR:Q9BZD4 BioGRID:BG-545452|IntAct:EBI-1646673 IPI NCBITaxon:9606 UniProtKB:Q02224 20130103 PRO:KER PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) located_in GO:0000776 kinetochore PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q02224 20121023 PRO:KER PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) acts_upstream_of_or_within GO:0033674 positive regulation of kinase activity PMID:22801780 EXP NCBITaxon:9606 UniProtKB:Q02224 20121023 PRO:KER Target=PR:O60566. PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17785528 EXP NCBITaxon:9606 UniProtKB:Q02224 20121023 PRO:KER Target=PR:O60566. PR:Q02224 centromere-associated protein E (human) CENP-E (human)|CENPE|centromere protein E (human)|hCENPE|kinesin-7 (human)|kinesin-related protein CENPE (human) acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:15592459 EXP NCBITaxon:9606 UniProtKB:Q02224 20121023 PRO:KER PR:Q02535 DNA-binding protein inhibitor ID-3 (human) 1R21|BHLHB25|class B basic helix-loop-helix protein 25 (human)|HEIR1|helix-loop-helix protein HEIR-1 (human)|hID3|ID-like protein inhibitor HLH 1R21 (human)|ID3|inhibitor of differentiation 3 (human)|inhibitor of DNA binding 3 (human) acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:14627819 IDA NCBITaxon:9606 UniProtKB:Q02535 20080301 PRO:CNA PR:Q02535-1 DNA-binding protein inhibitor ID-3 isoform 1 (human) hID3/iso:1 enables GO:0003714 transcription corepressor activity PMID:8437843 IDA NCBITaxon:9606 UniProtKB:Q02535-1 20080301 PRO:CNA PR:Q02535-1 DNA-binding protein inhibitor ID-3 isoform 1 (human) hID3/iso:1 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:1628620 IDA NCBITaxon:9606 UniProtKB:Q02535-1 20080301 PRO:CNA PR:Q02535-1 DNA-binding protein inhibitor ID-3 isoform 1 (human) hID3/iso:1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:8437843 IDA NCBITaxon:9606 UniProtKB:Q02535-1 20080301 PRO:CNA PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI enables GO:0046982 protein heterodimerization activity PR:P81183-1|PR:P81183-2 MGI_ref:1203354|PMID:9560339 IPI NCBITaxon:10090 MGI:1342540 20090513 MGI:MGI PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI enables GO:0046982 protein heterodimerization activity PR:Q8C208-1 MGI_ref:1333610|PMID:10218586 IPI NCBITaxon:10090 MGI:1342540 20090515 MGI:MGI PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI located_in GO:0005634 nucleus MGI_ref:2652944|PMID:12617992 IDA NCBITaxon:10090 MGI:1342540 20090420 MGI:MGI part_of(CL:0000236) PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:12617992 IDA NCBITaxon:10090 UniProtKB:Q03267-1 20090420 PRO:HJD PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI acts_upstream_of_or_within GO:0001779 natural killer cell differentiation PMID:7923373 IMP NCBITaxon:10090 MGI_allele:2158738 UniProtKB:Q03267-1 20090407 PRO:HJD PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI acts_upstream_of_or_within GO:0051138 positive regulation of NK T cell differentiation MGI_ref:1340364|PMID:10366784 IMP NCBITaxon:10090 MGI_allele:2158690|MGI_allele:2158738 MGI:1342540 20090406 MGI:MGI PR:Q03267-1 DNA-binding protein Ikaros isoform VI (mouse) mIKZF1/iso:VI acts_upstream_of_or_within GO:0060041 retina development in camera-type eye MGI_ref:3831471|PMID:18940586 IMP NCBITaxon:10090 MGI_allele:2158690 MGI:1342540 20090515 MGI:MGI results_in_development_of(EMAP:4342) PR:Q04592-1 proprotein convertase subtilisin/kexin type 5 isoform PC5B (mouse) mPCSK5/iso:PC5B|proprotein convertase subtilisin/kexin type 5 isoform Long (mouse) located_in GO:0005794 Golgi apparatus MGI_ref:84424|PMID:8947550 IDA NCBITaxon:10090 MGI:97515 20090410 MGI:MGI PR:Q04592-2 proprotein convertase subtilisin/kexin type 5 isoform PC5A (mouse) mPCSK5/iso:PC5A|proprotein convertase subtilisin/kexin type 5 isoform Short (mouse) located_in GO:0030141 secretory granule MGI_ref:84424|PMID:8947550 IDA NCBITaxon:10090 MGI:97515 20090410 MGI:MGI PR:Q05860-2 formin-1 isoform 2 (mouse) formin-1 (IB)|formin-1 IB (mouse)|mFMN1/iso:2 enables GO:0008017 microtubule binding MGI_ref:3622493|PMID:16480715 IDA NCBITaxon:10090 MGI:101815 20140421 MGI:MGI PR:Q05860-2 formin-1 isoform 2 (mouse) formin-1 (IB)|formin-1 IB (mouse)|mFMN1/iso:2 located_in GO:0015630 microtubule cytoskeleton MGI_ref:3622493|PMID:16480715 IDA NCBITaxon:10090 MGI:101815 20140421 MGI:MGI occurs_in(CL:0000057) PR:Q05860-2 formin-1 isoform 2 (mouse) formin-1 (IB)|formin-1 IB (mouse)|mFMN1/iso:2 acts_upstream_of_or_within GO:0048813 dendrite morphogenesis MGI_ref:5289763|PMID:21818269 IGI NCBITaxon:10090 MGI:893591 MGI:101815 20140422 MGI:MGI occurs_in(CL:0002608) PR:Q05860-2 formin-1 isoform 2 (mouse) formin-1 (IB)|formin-1 IB (mouse)|mFMN1/iso:2 acts_upstream_of_or_within GO:0048813 dendrite morphogenesis MGI_ref:5289763|PMID:21818269 IMP NCBITaxon:10090 MGI:101815 20140422 MGI:MGI occurs_in(CL:0002608) PR:Q05860-5 formin-1 isoform 5 (mouse) formin-1 (IV)|formin-1 IV (mouse)|mFMN1/iso:5 enables GO:0005515 protein binding PR:P26231 MGI_ref:3027450|PMID:14647292 IPI NCBITaxon:10090 MGI:101815 20050920 MGI:MGI PR:Q05860-5 formin-1 isoform 5 (mouse) formin-1 (IV)|formin-1 IV (mouse)|mFMN1/iso:5 located_in GO:0005737 cytoplasm MGI_ref:3798334|PMID:18560567 IDA NCBITaxon:10090 MGI:101815 20140422 MGI:MGI occurs_in(CL:0002518) PR:Q05860-5 formin-1 isoform 5 (mouse) formin-1 (IV)|formin-1 IV (mouse)|mFMN1/iso:5 located_in GO:0015630 microtubule cytoskeleton MGI_ref:3798334|PMID:18560567 IDA NCBITaxon:10090 MGI:101815 20140422 MGI:MGI occurs_in(CL:0002518) PR:Q05860-5 formin-1 isoform 5 (mouse) formin-1 (IV)|formin-1 IV (mouse)|mFMN1/iso:5 acts_upstream_of_or_within GO:0001822 kidney development MGI_ref:1097517|PMID:9234242 IMP NCBITaxon:10090 MGI_allele:3800994 MGI:101815 20140421 MGI:MGI occurs_in(MA:0000368) PR:Q05860-6 formin-1 isoform 6 (mouse) formin-1 (V)|formin-1 V (mouse)|mFMN1/iso:6 enables GO:0005515 protein binding PR:P26231 MGI_ref:3027450|PMID:14647292 IPI NCBITaxon:10090 MGI:101815 20140421 MGI:MGI PR:Q06402 1-aminocyclopropane-1-carboxylate synthase 2 (Arabidopsis thaliana) ACC synthase 2 (Arabidopsis thaliana)|ACC1|ACS2|At-ACS2|At1g01480|F22L4.4|S-adenosyl-L-methionine methylthioadenosine-lyase 2 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0010365 positive regulation of ethylene biosynthetic process PMID:15539472|PMID:18182027|PMID:20659280 EXP NCBITaxon:3702 UniProtKB:Q06402 20140402 PRO:LVM PR:Q07813-1 apoptosis regulator BAX isoform Alpha (mouse) mBAX/iso:Alpha acts_upstream_of_or_within GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand MGI_ref:67275|PMID:8358790 IDA NCBITaxon:10090 MGI:99702 20130529 MGI:MGI PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:000028379 PMID:11583631 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:O54918 PMID:11583631 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:Q07812 PMID:8596636 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:Q16611 PMID:8596636 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:Q61337 PMID:11583631 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 enables GO:0005515 protein binding PR:Q92934-1 PMID:10949026 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090810 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:10949026 EXP NCBITaxon:9606 UniProtKB:Q07817-1 20090810 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:8596636 EXP NCBITaxon:9606 UniProtKB:Q07817-1 20090918 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 decreased enables GO:0005515 protein binding PR:000002843 PR:000026167 PMID:10949026 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090810 PRO:JAN PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human) hBCL2L1/iso:1 NOT enables GO:0005515 protein binding PR:000026133 PMID:10949026 IPI NCBITaxon:9606 UniProtKB:Q07817-1 20090810 PRO:JAN PR:Q08380-1 galectin-3-binding protein isoform 1 (human) hLGALS3BP/iso:1 has_role CHEBI:59163 biomarker PMID:18829504 EXP NCBITaxon:9606 UniProtKB:Q08380-1 20100525 SALO:AJ PR:Q08460-1 calcium-activated potassium channel subunit alpha-1 isoform 1 (mouse) mKCNMA1/iso:1 enables GO:0005249 voltage-gated potassium channel activity MGI_ref:3607626|PMID:16081418 IDA NCBITaxon:10090 MGI:99923 20140331 MGI:MGI PR:Q08460-1 calcium-activated potassium channel subunit alpha-1 isoform 1 (mouse) mKCNMA1/iso:1 enables GO:0015269 calcium-activated potassium channel activity MGI_ref:3607626|PMID:16081418 IDA NCBITaxon:10090 MGI:99923 20140331 MGI:MGI PR:Q08460-4 calcium-activated potassium channel subunit alpha-1 isoform 4 (mouse) calcium-activated potassium channel subunit alpha-1 isoform STREX-1 (mouse)|mKCNMA1/iso:4 enables GO:0005249 voltage-gated potassium channel activity MGI_ref:3607626|PMID:16081418 IDA NCBITaxon:10090 MGI:99923 20080811 MGI:MGI PR:Q08460-4 calcium-activated potassium channel subunit alpha-1 isoform 4 (mouse) calcium-activated potassium channel subunit alpha-1 isoform STREX-1 (mouse)|mKCNMA1/iso:4 enables GO:0015269 calcium-activated potassium channel activity MGI_ref:3607626|PMID:16081418 IDA NCBITaxon:10090 MGI:99923 20080813 MGI:MGI PR:Q08775-8 runt-related transcription factor 2 isoform 8 (mouse) mRUNX2/iso:8|runx2 y1 (mouse) located_in GO:0005737 cytoplasm MGI_ref:3051083|PMID:15225881 IDA NCBITaxon:10090 MGI:99829 20080811 MGI:MGI PR:Q08775-9 runt-related transcription factor 2 isoform 9 (mouse) mRUNX2/iso:9|runx2 y2 (mouse) located_in GO:0005737 cytoplasm MGI_ref:3051083|PMID:15225881 IDA NCBITaxon:10090 MGI:99829 20140512 MGI:MGI PR:Q08999-1 retinoblastoma-like protein 2 isoform 1 (human) hRBL2/iso:1 enables GO:0005515 protein binding PMID:8361765 IPI NCBITaxon:9606 UniProtKB:Q08999-1 20080301 PRO:CNA PR:Q0QWG9 delphilin (mouse) glutamate receptor, ionotropic, delta 2-interacting protein 1 (mouse)|Grid2ip|mGRID2IP acts_upstream_of_or_within GO:0060292 long-term synaptic depression PMID:18509461 IMP NCBITaxon:10090 MGI_allele:3796575 UniProtKB:Q0QWG9 20100325 PRO:HJD PR:Q0QWG9-1 delphilin isoform 1 (mouse) mGRID2IP/iso:1 enables GO:0005515 protein binding PR:P05480 PMID:11826110 IPI NCBITaxon:10090 UniProtKB:Q0QWG9-1 20100325 PRO:HJD PR:Q0QWG9-1 delphilin isoform 1 (mouse) mGRID2IP/iso:1 enables GO:0005515 protein binding PR:P62962 PMID:11826110 IPI NCBITaxon:10090 UniProtKB:Q0QWG9-1 20100325 PRO:HJD PR:Q0QWG9-1 delphilin isoform 1 (mouse) mGRID2IP/iso:1 enables GO:0005515 protein binding PR:Q61625 PMID:11826110 IPI NCBITaxon:10090 UniProtKB:Q0QWG9-1 20100325 PRO:HJD PR:Q0QWG9-1 delphilin isoform 1 (mouse) mGRID2IP/iso:1 enables GO:0005515 protein binding PR:Q9JJV2 PMID:11826110 IPI NCBITaxon:10090 UniProtKB:Q0QWG9-1 20100325 PRO:HJD PR:Q0QWG9-2 delphilin isoform 2 (mouse) mGRID2IP/iso:2 enables GO:0005515 protein binding PR:Q61625 MGI_ref:3851319|PMID:16168524 IPI NCBITaxon:10090 MGI:2176213 20111221 MGI:MGI PR:Q0QWG9-2 delphilin isoform 2 (mouse) mGRID2IP/iso:2 located_in GO:0043197 dendritic spine MGI_ref:3851319|PMID:16168524 IDA NCBITaxon:10090 MGI:2176213 20111221 MGI:MGI PR:Q0QWG9-2 delphilin isoform 2 (mouse) mGRID2IP/iso:2 located_in GO:0045202 synapse MGI_ref:3851319|PMID:16168524 IDA NCBITaxon:10090 MGI:2176213 20120515 MGI:MGI PR:Q0QWG9-3 delphilin isoform 3 (mouse) mGRID2IP/iso:3 enables GO:0005515 protein binding PR:Q61625 MGI_ref:3851319|PMID:16168524 IPI NCBITaxon:10090 MGI:2176213 20100323 MGI:MGI PR:Q0QWG9-3 delphilin isoform 3 (mouse) mGRID2IP/iso:3 located_in GO:0043197 dendritic spine MGI_ref:3851319|PMID:16168524 IDA NCBITaxon:10090 MGI:2176213 20100323 MGI:MGI PR:Q0QWG9-3 delphilin isoform 3 (mouse) mGRID2IP/iso:3 located_in GO:0045202 synapse MGI_ref:3851319|PMID:16168524 IDA NCBITaxon:10090 MGI:2176213 20120515 MGI:MGI PR:Q12809 potassium voltage-gated channel subfamily H member 2 (human) Eag homolog (human)|Eag-related protein 1 (human)|ERG|ERG-1 (human)|ERG1|ether-a-go-go-related gene potassium channel 1 (human)|ether-a-go-go-related protein 1 (human)|H-ERG|HERG|hERG-1|hERG1|hKCNH2|KCNH2|voltage-gated potassium channel subunit Kv11.1 (human) acts_upstream_of_or_within GO:0006936 muscle contraction PMID:7736582 IDA NCBITaxon:9606 UniProtKB:Q12809 20080601 PRO:CNA PR:Q12809 potassium voltage-gated channel subfamily H member 2 (human) Eag homolog (human)|Eag-related protein 1 (human)|ERG|ERG-1 (human)|ERG1|ether-a-go-go-related gene potassium channel 1 (human)|ether-a-go-go-related protein 1 (human)|H-ERG|HERG|hERG-1|hERG1|hKCNH2|KCNH2|voltage-gated potassium channel subunit Kv11.1 (human) acts_upstream_of_or_within GO:0008016 regulation of heart contraction PMID:7736582 IDA NCBITaxon:9606 UniProtKB:Q12809 20080601 PRO:CNA PR:Q12809-1 potassium voltage-gated channel subfamily H member 2 isoform A (human) hKCNH2/iso:A enables GO:0030552 cAMP binding PMID:10837251 IDA NCBITaxon:9606 UniProtKB:Q12809-1 20080601 PRO:CNA PR:Q12809-2 potassium voltage-gated channel subfamily H member 2 isoform B (human) hKCNH2/iso:B contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9351446 IDA NCBITaxon:9606 UniProtKB:Q12809-2 20080601 PRO:CNA PR:Q12809-5 potassium voltage-gated channel subfamily H member 2 isoform A-USO (human) hKCNH2/iso:A-USO part_of GO:0008076 voltage-gated potassium channel complex PMID:9765245 IDA NCBITaxon:9606 UniProtKB:Q12809-5 20080601 PRO:CNA PR:Q12809-5 potassium voltage-gated channel subfamily H member 2 isoform A-USO (human) hKCNH2/iso:A-USO altered|contributes_to enables GO:0005251 delayed rectifier potassium channel activity PR:000002666 PMID:9765245 IDA NCBITaxon:9606 UniProtKB:Q12809-5 20080601 PRO:CNA PR:Q12834 cell division cycle protein 20 homolog (human) CDC20|hCDC20|p55CDC (human) enables GO:0005515 protein binding PR:O60566 PMID:11030144|PMID:20624902 IPI NCBITaxon:9606 UniProtKB:Q12834 20121112 PRO:KER Timing=interphase and mitosis. PR:Q12834 cell division cycle protein 20 homolog (human) CDC20|hCDC20|p55CDC (human) enables GO:0005515 protein binding PR:Q13257 PMID:20624902 IPI NCBITaxon:9606 UniProtKB:Q12834 20121112 PRO:KER Timing=interphase and mitosis. PR:Q13042 cell division cycle protein 16 homolog (human) ANAPC6|anaphase-promoting complex subunit 6 (human)|APC6 (human)|CDC16|CDC16 homolog (human)|CDC16Hs (human)|cyclosome subunit 6 (human)|hCDC16 enables GO:0005515 protein binding PR:O60566 PMID:11030144 IPI NCBITaxon:9606 UniProtKB:Q13042 20121112 PRO:KER PR:Q13043 serine/threonine-protein kinase 4 (human) hSTK4|KRS2|mammalian STE20-like protein kinase 1 (human)|MST-1 (human)|MST1|serine/threonine-protein kinase Krs-2 (human)|STE20-like kinase MST1 (human)|STK4 enables GO:0005515 protein binding PR:Q96GD4 PMID:20171103 IPI NCBITaxon:9606 UniProtKB:Q13043 20121121 PRO:KER PR:Q13043 serine/threonine-protein kinase 4 (human) hSTK4|KRS2|mammalian STE20-like protein kinase 1 (human)|MST-1 (human)|MST1|serine/threonine-protein kinase Krs-2 (human)|STE20-like kinase MST1 (human)|STK4 acts_upstream_of_or_within GO:0006469 negative regulation of protein kinase activity PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q13043 20121121 PRO:KER Target=PR:Q96GD4. Target=PR:Q15208. PR:Q13043 serine/threonine-protein kinase 4 (human) hSTK4|KRS2|mammalian STE20-like protein kinase 1 (human)|MST-1 (human)|MST1|serine/threonine-protein kinase Krs-2 (human)|STE20-like kinase MST1 (human)|STK4 acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q13043 20121121 PRO:KER PR:Q13043 serine/threonine-protein kinase 4 (human) hSTK4|KRS2|mammalian STE20-like protein kinase 1 (human)|MST-1 (human)|MST1|serine/threonine-protein kinase Krs-2 (human)|STE20-like kinase MST1 (human)|STK4 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q13043 20121121 PRO:KER Target=PR:Q96GD4. Target=PR:Q15208. PR:Q13043 serine/threonine-protein kinase 4 (human) hSTK4|KRS2|mammalian STE20-like protein kinase 1 (human)|MST-1 (human)|MST1|serine/threonine-protein kinase Krs-2 (human)|STE20-like kinase MST1 (human)|STK4 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q13043 20121121 PRO:KER PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0005515 protein binding PR:O43684 BioGRID:BG-718926 IPI NCBITaxon:9606 UniProtKB:Q13257 20130103 PRO:KER PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0005515 protein binding PR:O60566 PMID:20624902 IPI NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER Timing=interphase and mitosis. PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0005515 protein binding PR:P25054 BioGRID:BG-302957 IPI NCBITaxon:9606 UniProtKB:Q13257 20130103 PRO:KER PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0005515 protein binding PR:Q12834 PMID:20624902 IPI NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER Timing=interphase and mitosis. PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0005515 protein binding PR:Q9Y6D9 BioGRID:BG-718929|MINT:MINT-8289277 IPI NCBITaxon:9606 UniProtKB:Q13257 20130103 PRO:KER PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0031625 ubiquitin protein ligase binding PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER Timing=interphase and mitosis. Target=PR:Q12834. PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) enables GO:0055105 ubiquitin-protein transferase inhibitor activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER Target=PR:000035369. Target=PR:000035371. PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) located_in GO:0000776 kinetochore PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) acts_upstream_of_or_within GO:0051444 negative regulation of ubiquitin-protein transferase activity PMID:15525512 EXP NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER Target=PR:000035369. Target=PR:000035371. PR:Q13257 mitotic spindle assembly checkpoint protein MAD2A (human) hMAD2L1|HsMAD2|MAD2|MAD2-like protein 1 (human)|MAD2L1|mitotic arrest deficient 2-like protein 1 (human) NOT acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:15592459 EXP NCBITaxon:9606 UniProtKB:Q13257 20121023 PRO:KER PR:Q13315 serine-protein kinase ATM (human) A-T mutated (human)|ataxia telangiectasia mutated (human)|ATM|hATM enables GO:0004672 protein kinase activity PMID:22071147 EXP NCBITaxon:9606 UniProtKB:Q13315 20121105 PRO:KER PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 enables GO:0004674 protein serine/threonine kinase activity PMID:8798490 TAS NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA Note=Occurs after activation by PR:P61586 GTP bound PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 enables GO:0031267 small GTPase binding PMID:14660612|PMID:15475352 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:10436159 TAS NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PMID:8798490 TAS NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:10436159 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human) hROCK1/iso:1 acts_upstream_of_or_within GO:0051260 protein homooligomerization PMID:15291762 IDA NCBITaxon:9606 UniProtKB:Q13464-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 enables GO:0003700 DNA-binding transcription factor activity PMID:10823886 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 enables GO:0003712 transcription coregulator activity PMID:10980615 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 located_in GO:0005634 nucleus PMID:10980615|PMID:15280432 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 located_in GO:0005737 cytoplasm PMID:15280432 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 part_of GO:0005667 transcription factor complex PMID:12374795 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17142805|PMID:8774881 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 acts_upstream_of_or_within GO:0060395 SMAD protein signal transduction PMID:10980615|PMID:15350224|PMID:9346966 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:14633973 IDA NCBITaxon:9606 UniProtKB:Q13485-1 20080301 PRO:CNA PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human) hTRPC3/iso:1 enables GO:0005515 protein binding PMID:15744307 IPI NCBITaxon:9606 UniProtKB:Q13507-1 20080701 PRO:CNA PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human) hTRPC3/iso:1 enables GO:0015279 store-operated calcium channel activity PMID:9215637 IDA NCBITaxon:9606 UniProtKB:Q13507-1 20080701 PRO:CNA PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human) hTRPC3/iso:1 located_in GO:0005886 plasma membrane PMID:9368034 IDA NCBITaxon:9606 UniProtKB:Q13507-1 20080701 PRO:CNA PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human) hTRPC3/iso:1 acts_upstream_of_or_within GO:0007602 phototransduction PMID:9215637 IDA NCBITaxon:9606 UniProtKB:Q13507-1 20080701 PRO:CNA PR:Q13616-1 cullin-1 isoform 1 (human) hCUL1/iso:1 enables GO:0005515 protein binding PR:P62877-1 PMID:12504026|PMID:15537541 IPI NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:Q13616-1 cullin-1 isoform 1 (human) hCUL1/iso:1 enables GO:0005515 protein binding PR:Q86VP6-1 PMID:12504026|PMID:15537541 IPI NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:Q13616-1 cullin-1 isoform 1 (human) hCUL1/iso:1 NOT part_of GO:0019005 SCF ubiquitin ligase complex PMID:10713156|PMID:10921923|PMID:12504026 IDA NCBITaxon:9606 UniProtKB:Q13616-1 20080301 PRO:CNA PR:Q13705-1 activin receptor type-2B isoform ActR-IIB2 (human) hACVR2B/iso:ActR-IIB2 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:8161782 TAS NCBITaxon:9606 UniProtKB:Q13705-1 20080301 PRO:CNA PR:Q13705-2 activin receptor type-2B isoform ActR-IIBtrunc (human) activin receptor type-2B isoform ActR-IIB1 (human)|hACVR2B/iso:ActR-IIB1 has_agent SO:0001587 stop_gained PMID:9916847 EXP NCBITaxon:9606 UniProtKB:Q13705-2 20080301 PRO:CNA PR:Q13705-2 activin receptor type-2B isoform ActR-IIBtrunc (human) activin receptor type-2B isoform ActR-IIB1 (human)|hACVR2B/iso:ActR-IIB1 NOT enables GO:0016362 activin receptor activity, type II PMID:9916847 EXP NCBITaxon:9606 UniProtKB:Q13705-2 20080301 PRO:CNA PR:Q13740 CD166 antigen (human) activated leukocyte cell adhesion molecule (human)|ALCAM|CD166 (human)|hALCAM|MEMD located_in GO:0016020 membrane PMID:18347173 EXP NCBITaxon:9606 UniProtKB:Q13740 20090303 PRO:CNA PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 enables GO:0005515 protein binding PR:P12643 PMID:7791754 IPI NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA Note=BMP2 organism source not directly specified but, following the acknowledgements, the indicated source person (J Wozney) is listed as submitter of sequence for the human protein (see UniProtKB:P12643 and PMID:3201241) PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 enables GO:0005515 protein binding PR:P18075 PMID:7791754 IPI NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA Note=BMP7 organism source not directly specified but, following the acknowledgements, the indicated source person (K Sampath) is listed as submitter of sequence for the human protein (see UniProtKB:P18075 and PMID:2357959) PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 located_in GO:0005886 plasma membrane PMID:7791754 IDA NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 located_in GO:0009986 cell surface PMID:10712517 IDA NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 part_of GO:0043235 receptor complex PMID:7791754 IDA NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA PR:Q13873-1 bone morphogenetic protein receptor type-2 isoform 1 (human) hBMPR2/iso:1 acts_upstream_of_or_within GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PMID:7644468 IDA NCBITaxon:9606 UniProtKB:Q13873-1 20080301 PRO:CNA PR:Q14766-1 latent-transforming growth factor beta-binding protein 1 isoform Long (human) hLTBP1/iso:Long|latent-transforming growth factor beta-binding protein 1 isoform LTBP-1L (human) enables GO:0005024 transforming growth factor beta receptor activity PMID:8537398 IDA NCBITaxon:9606 UniProtKB:Q14766-1 20080301 PRO:CNA PR:Q14766-1 latent-transforming growth factor beta-binding protein 1 isoform Long (human) hLTBP1/iso:Long|latent-transforming growth factor beta-binding protein 1 isoform LTBP-1L (human) located_in GO:0031012 extracellular matrix PMID:8537398 IDA NCBITaxon:9606 UniProtKB:Q14766-1 20080301 PRO:CNA PR:Q148R9 regulator of G-protein signaling 9-binding protein (mouse) mRGS9BP|R9ap|RGS9-anchoring protein (mouse)|Rgs9bp located_in GO:0001750 photoreceptor outer segment MGI_ref:5507748|PMID:23555598 IDA NCBITaxon:10090 MGI:2384418 20150108 MGI:MGI part_of(CL:0000604) PR:Q14AT5-1 anoctamin-7 isoform 1 (mouse) mANO7/iso:1 enables GO:0005229 intracellularly calcium-gated chloride channel activity MGI_ref:4838963|PMID:20056604 IDA NCBITaxon:10090 MGI:3052714 20140108 MGI:MGI PR:Q14AT5-1 anoctamin-7 isoform 1 (mouse) mANO7/iso:1 acts_upstream_of_or_within GO:0006821 chloride transport MGI_ref:4838963|PMID:20056604 IDA NCBITaxon:10090 MGI:3052714 20111118 MGI:MGI PR:Q14AT5-2 anoctamin-7 isoform 2 (mouse) mANO7/iso:2 enables GO:0005229 intracellularly calcium-gated chloride channel activity MGI_ref:4838963|PMID:20056604 IDA NCBITaxon:10090 MGI:3052714 20140220 MGI:MGI PR:Q14AT5-2 anoctamin-7 isoform 2 (mouse) mANO7/iso:2 located_in GO:0005634 nucleus MGI_ref:4838963|PMID:20056604 IDA NCBITaxon:10090 MGI:3052714 20111118 MGI:MGI PR:Q14AT5-2 anoctamin-7 isoform 2 (mouse) mANO7/iso:2 acts_upstream_of_or_within GO:0006821 chloride transport MGI_ref:4838963|PMID:20056604 IDA NCBITaxon:10090 MGI:3052714 20140220 MGI:MGI PR:Q14BU0-2 unique cartilage matrix-associated protein isoform 2 (mouse) mUCMA/iso:2 located_in GO:0016235 aggresome MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20110126 MGI:MGI PR:Q14BU0-2 unique cartilage matrix-associated protein isoform 2 (mouse) mUCMA/iso:2 located_in GO:0048471 perinuclear region of cytoplasm MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20110126 MGI:MGI PR:Q14BU0-3 unique cartilage matrix-associated protein isoform 3 (mouse) mUCMA/iso:3 located_in GO:0005615 extracellular space MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20120215 MGI:MGI part_of(CL:0000138) PR:Q14BU0-4 unique cartilage matrix-associated protein isoform 4 (mouse) mUCMA/iso:4 located_in GO:0016235 aggresome MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20120215 MGI:MGI PR:Q14BU0-4 unique cartilage matrix-associated protein isoform 4 (mouse) mUCMA/iso:4 located_in GO:0048471 perinuclear region of cytoplasm MGI_ref:4421086|PMID:19819238 IDA NCBITaxon:10090 MGI:1915777 20120215 MGI:MGI PR:Q15013 MAD2L1-binding protein (human) caught by MAD2 protein (human)|CMT2|hMAD2L1BP|KIAA0110|MAD2L1BP|p31(comet) (human) acts_upstream_of_or_within GO:0032091 negative regulation of protein binding PMID:22566641 EXP NCBITaxon:9606 UniProtKB:Q15013 20121121 PRO:KER Target=PR:Q12834. Target=PR:O60566. PR:Q15013 MAD2L1-binding protein (human) caught by MAD2 protein (human)|CMT2|hMAD2L1BP|KIAA0110|MAD2L1BP|p31(comet) (human) acts_upstream_of_or_within GO:0032091 negative regulation of protein binding PMID:22566641 EXP NCBITaxon:9606 UniProtKB:Q15013 20121121 PRO:KER Target=PR:Q13257. Target=PR:O60566. PR:Q15013 MAD2L1-binding protein (human) caught by MAD2 protein (human)|CMT2|hMAD2L1BP|KIAA0110|MAD2L1BP|p31(comet) (human) acts_upstream_of_or_within GO:0042327 positive regulation of phosphorylation PMID:22566641 EXP NCBITaxon:9606 UniProtKB:Q15013 20121121 PRO:KER Target=PR:Q12834. PR:Q15172 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (human) hPPP2R5A|PP2A B subunit isoform B'-alpha (human)|PP2A B subunit isoform B56-alpha (human)|PP2A B subunit isoform PR61-alpha (human)|PP2A B subunit isoform R5-alpha (human)|PPP2R5A|PR61alpha (human) enables GO:0005515 protein binding PR:000035428 PMID:23079597 IPI NCBITaxon:9606 UniProtKB:Q15172 20130116 PRO:KER PR:Q15172 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (human) hPPP2R5A|PP2A B subunit isoform B'-alpha (human)|PP2A B subunit isoform B56-alpha (human)|PP2A B subunit isoform PR61-alpha (human)|PP2A B subunit isoform R5-alpha (human)|PPP2R5A|PR61alpha (human) located_in GO:0000776 kinetochore PMID:23079597 EXP NCBITaxon:9606 UniProtKB:Q15172 20130116 PRO:KER PR:Q15208 serine/threonine-protein kinase 38 (human) hSTK38|NDR1|NDR1 protein kinase (human)|nuclear Dbf2-related kinase 1 (human)|STK38 enables GO:0005515 protein binding PR:Q96GD4 PMID:20171103 IPI NCBITaxon:9606 UniProtKB:Q15208 20121121 PRO:KER PR:Q15208 serine/threonine-protein kinase 38 (human) hSTK38|NDR1|NDR1 protein kinase (human)|nuclear Dbf2-related kinase 1 (human)|STK38 acts_upstream_of_or_within GO:0006469 negative regulation of protein kinase activity PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q15208 20121121 PRO:KER Target=PR:Q96GD4. PR:Q15208 serine/threonine-protein kinase 38 (human) hSTK38|NDR1|NDR1 protein kinase (human)|nuclear Dbf2-related kinase 1 (human)|STK38 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:20171103 EXP NCBITaxon:9606 UniProtKB:Q15208 20121121 PRO:KER PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 enables GO:0005102 signaling receptor binding PMID:9136927|PMID:9748228 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 enables GO:0005515 protein binding PR:Q7Z3T8 PMID:17356069 IPI NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 located_in GO:0005737 cytoplasm PMID:11509558 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8637600 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15797-1 mothers against decapentaplegic homolog 1 isoform 1 (human) hSMAD1/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785 IDA NCBITaxon:9606 UniProtKB:Q15797-1 20080301 PRO:CNA PR:Q15911-1 zinc finger homeobox protein 3 isoform 1 (human) ATBF1-A (human)|hZFHX3/iso:1 acts_upstream_of_or_within GO:0045662 negative regulation of myoblast differentiation PMID:11312261 EXP NCBITaxon:9606 UniProtKB:Q15911-1 20121119 PRO:AAA PR:Q15911-2 zinc finger homeobox protein 3 isoform 2 (human) ATBF1-B (human)|hZFHX3/iso:2 acts_upstream_of_or_within GO:0045663 positive regulation of myoblast differentiation PMID:11312261 EXP NCBITaxon:9606 UniProtKB:Q15911-2 20121119 PRO:AAA PR:Q16281-1 cyclic nucleotide-gated cation channel alpha-3 isoform 1 (human) hCNGA3/iso:1 enables GO:0015276 ligand-gated monoatomic ion channel activity PMID:9517456 IDA NCBITaxon:9606 UniProtKB:Q16281-1 20080601 PRO:CNA PR:Q16281-1 cyclic nucleotide-gated cation channel alpha-3 isoform 1 (human) hCNGA3/iso:1 part_of GO:0017071 intracellular cyclic nucleotide activated cation channel complex PMID:12467591 IDA NCBITaxon:9606 UniProtKB:Q16281-1 20080601 PRO:CNA PR:Q16281-1 cyclic nucleotide-gated cation channel alpha-3 isoform 1 (human) hCNGA3/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:9517456 IDA NCBITaxon:9606 UniProtKB:Q16281-1 20080601 PRO:CNA PR:Q16322-1 potassium voltage-gated channel subfamily A member 10 isoform 1 (human) hKCNA10/iso:1 part_of GO:0008076 voltage-gated potassium channel complex PMID:12060596 IDA NCBITaxon:9606 UniProtKB:Q16322-1 20080601 PRO:CNA PR:Q16322-1 potassium voltage-gated channel subfamily A member 10 isoform 1 (human) hKCNA10/iso:1 contributes_to enables GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity PMID:10836990|PMID:9177773 IDA NCBITaxon:9606 UniProtKB:Q16322-1 20080601 PRO:CNA PR:Q16322-1 potassium voltage-gated channel subfamily A member 10 isoform 1 (human) hKCNA10/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10836990 IDA NCBITaxon:9606 UniProtKB:Q16322-1 20080601 PRO:CNA PR:Q16671-1 anti-Muellerian hormone type-2 receptor isoform 1 (human) hAMHR2/iso:1 enables GO:0038023 signaling receptor activity PMID:7493017 IDA NCBITaxon:9606 UniProtKB:Q16671-1 20080301 PRO:CNA PR:Q16671-1 anti-Muellerian hormone type-2 receptor isoform 1 (human) hAMHR2/iso:1 enables GO:0042562 hormone binding PMID:14750901|PMID:7493017 IDA NCBITaxon:9606 UniProtKB:Q16671-1 20080301 PRO:CNA PR:Q16671-1 anti-Muellerian hormone type-2 receptor isoform 1 (human) hAMHR2/iso:1 acts_upstream_of_or_within GO:0001880 Mullerian duct regression PMID:14750901 IDA NCBITaxon:9606 UniProtKB:Q16671-1 20080301 PRO:CNA PR:Q16671-1 anti-Muellerian hormone type-2 receptor isoform 1 (human) hAMHR2/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:7493017 IDA NCBITaxon:9606 UniProtKB:Q16671-1 20080301 PRO:CNA PR:Q16671-1 anti-Muellerian hormone type-2 receptor isoform 1 (human) hAMHR2/iso:1 acts_upstream_of_or_within GO:0007548 sex differentiation PMID:12834017 IDA NCBITaxon:9606 UniProtKB:Q16671-1 20080301 PRO:CNA PR:Q17ST2-1 potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse) mKCNA7/iso:1|potassium voltage-gated channel subfamily A member 7 isoform Kv1.7L (mouse) enables GO:0005249 voltage-gated potassium channel activity PMID:16801386 IDA NCBITaxon:10090 UniProtKB:Q17ST2-1 20080601 PRO:CNA PR:Q17ST2-1 potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse) mKCNA7/iso:1|potassium voltage-gated channel subfamily A member 7 isoform Kv1.7L (mouse) part_of GO:0008076 voltage-gated potassium channel complex PMID:16801386 IDA NCBITaxon:10090 UniProtKB:Q17ST2-1 20080601 PRO:CNA PR:Q17ST2-2 potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse) mKCNA7/iso:2|potassium voltage-gated channel subfamily A member 7 isoform Kv1.7S (mouse) enables GO:0005249 voltage-gated potassium channel activity PMID:16801386 IDA NCBITaxon:10090 UniProtKB:Q17ST2-2 20080601 PRO:CNA PR:Q17ST2-2 potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse) mKCNA7/iso:2|potassium voltage-gated channel subfamily A member 7 isoform Kv1.7S (mouse) part_of GO:0008076 voltage-gated potassium channel complex PMID:16801386 IDA NCBITaxon:10090 UniProtKB:Q17ST2-2 20080601 PRO:CNA PR:Q2VEB3 A-kinase anchor protein 6 isoform beta (mouse) mAKAP-beta|mAKAP6/iso:beta enables GO:0008179 adenylate cyclase binding PR:P84309 MGI_ref:4365477|PMID:19574217 IPI NCBITaxon:10090 MGI:3050566 20150209 MGI:MGI occurs_in(MA:0000072) PR:Q2VEB4 A-kinase anchor protein 6 isoform alpha (mouse) mAKAP-alpha|mAKAP6/iso:alpha enables GO:0005515 protein binding PR:Q9Z2A0 MGI_ref:3709575|PMID:16337591 IPI NCBITaxon:10090 MGI:3050566 20150206 MGI:MGI occurs_in(MA:0000168) PR:Q39011 shaggy-related protein kinase eta (Arabidopsis thaliana) ASK-eta (Arabidopsis thaliana)|ASK7|At-ASK7|At4g18710|AtSK21|BIN2|DWF12|F28A21.120|protein BRASSINOSTEROID INSENSITIVE 2 (Arabidopsis thaliana)|protein ULTRACURVATA 1 (Arabidopsis thaliana)|shaggy-related protein kinase 21 (Arabidopsis thaliana)|SK21|UCU1 enables GO:0046827 positive regulation of protein export from nucleus PMID:17873094|PMID:20387035 EXP NCBITaxon:3702 UniProtKB:Q39011 20130205 PRO:LVM Target=PR:Q8S307. Target=PR:000035745. PR:Q39011 shaggy-related protein kinase eta (Arabidopsis thaliana) ASK-eta (Arabidopsis thaliana)|ASK7|At-ASK7|At4g18710|AtSK21|BIN2|DWF12|F28A21.120|protein BRASSINOSTEROID INSENSITIVE 2 (Arabidopsis thaliana)|protein ULTRACURVATA 1 (Arabidopsis thaliana)|shaggy-related protein kinase 21 (Arabidopsis thaliana)|SK21|UCU1 located_in GO:0005634 nucleus PMID:20387035 EXP NCBITaxon:3702 UniProtKB:Q39011 20130205 PRO:CNA PR:Q39011 shaggy-related protein kinase eta (Arabidopsis thaliana) ASK-eta (Arabidopsis thaliana)|ASK7|At-ASK7|At4g18710|AtSK21|BIN2|DWF12|F28A21.120|protein BRASSINOSTEROID INSENSITIVE 2 (Arabidopsis thaliana)|protein ULTRACURVATA 1 (Arabidopsis thaliana)|shaggy-related protein kinase 21 (Arabidopsis thaliana)|SK21|UCU1 acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:17873094 EXP NCBITaxon:3702 UniProtKB:Q39011 20130205 PRO:LVM PR:Q39026 mitogen-activated protein kinase 6 (Arabidopsis thaliana) At-MPK6|At2g43790|AtMPK6|F18O19.10|MAP kinase 6 (Arabidopsis thaliana)|MPK6 enables GO:0005515 protein binding PR:P11035 PMID:20870959 IPI NCBITaxon:3702 UniProtKB:Q39026 20140415 PRO:CNA PR:P31809-4 CEACAM1a-2S (mouse) Bgp C (mouse)|Bgp1/2S (mouse)|BgpC (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Bgpc (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Ceacam1-2S (mouse)|CEA-related cell adhesion molecule 1, isoform 1/2S (mouse)|Ceacam1/D1,4S (mouse)|CEACAM1a-2S|mCEACAM1a/iso:2S located_in GO:0009897 external side of plasma membrane MGI_ref:5503958|PMID:10491101 IDA NCBITaxon:10090 MGI:1347245 20130905 MGI:MGI PR:P31809-4 CEACAM1a-2S (mouse) Bgp C (mouse)|Bgp1/2S (mouse)|BgpC (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Bgpc (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Ceacam1-2S (mouse)|CEA-related cell adhesion molecule 1, isoform 1/2S (mouse)|Ceacam1/D1,4S (mouse)|CEACAM1a-2S|mCEACAM1a/iso:2S located_in GO:0009897 external side of plasma membrane MGI_ref:81180|PMID:8896983 IDA NCBITaxon:10090 MGI:1347245 20141231 MGI:MGI PR:P31809-4 CEACAM1a-2S (mouse) Bgp C (mouse)|Bgp1/2S (mouse)|BgpC (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Bgpc (mouse)|carcinoembryonic antigen-related cell adhesion molecule 1 isoform Ceacam1-2S (mouse)|CEA-related cell adhesion molecule 1, isoform 1/2S (mouse)|Ceacam1/D1,4S (mouse)|CEACAM1a-2S|mCEACAM1a/iso:2S acts_upstream_of_or_within GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules MGI_ref:5503958|PMID:10491101 IDA NCBITaxon:10090 MGI:1347245 20130904 MGI:MGI PR:Q3TJI3 ubiquitin carboxyl-terminal hydrolase CYLD isoform 4 (mouse) mCYLD/iso:4 acts_upstream_of_or_within GO:0045581 negative regulation of T cell differentiation MGI_ref:5449492|PMID:23066153 IDA NCBITaxon:10090 MGI:1921506 20140305 MGI:MGI occurs_in(MA:0000142) PR:Q3TUF7-1 YEATS domain-containing protein 2 isoform 1 (mouse) mYEATS2/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:2447762 20120611 MGI:MGI PR:Q3UA06-1 pachytene checkpoint protein 2 homolog isoform 1 (mouse) mTRIP13/iso:1 enables GO:0005515 protein binding PR:P15209|PR:Q4G5Y1|PR:Q9D6I7|PR:Q9D6X5|PR:Q9DCX1 MGI_ref:3609918|PMID:11591653 IPI NCBITaxon:10090 MGI:1916966 20080828 MGI:MGI PR:Q3UA06-1 pachytene checkpoint protein 2 homolog isoform 1 (mouse) mTRIP13/iso:1 enables GO:0042802 identical protein binding PR:Q3UA06 MGI_ref:3609918|PMID:11591653 IPI NCBITaxon:10090 MGI:1916966 20080828 MGI:MGI PR:Q3UMU9-1 hepatoma-derived growth factor-related protein 2 isoform 1 (mouse) hepatoma-derived growth factor-related protein 2 isoform a|HRP-2 isoform 1 (mouse)|HRP-2 isoform a (mouse)|mHDGFRP2/iso:1 NOT enables GO:0003682 chromatin binding MGI_ref:5470382|PMID:22212508 IDA NCBITaxon:10090 MGI:1194492 20130522 MGI:MGI PR:Q3UMU9-4 hepatoma-derived growth factor-related protein 2 isoform 3 (mouse) hepatoma-derived growth factor-related protein 2 isoform c|HRP-2 isoform 3 (mouse)|HRP-2 isoform c (mouse)|mHDGFRP2/iso:3 enables GO:0003682 chromatin binding MGI_ref:5470382|PMID:22212508 IDA NCBITaxon:10090 MGI:1194492 20130522 MGI:MGI PR:Q4VAA2-1 protein CDV3 isoform 1 (mouse) mCDV3/iso:1|TTP36 (mouse) located_in GO:0005737 cytoplasm MGI_ref:2652310|PMID:12606058 IDA NCBITaxon:10090 MGI:2448759 20130213 MGI:MGI PR:Q4VAA2-1 protein CDV3 isoform 1 (mouse) mCDV3/iso:1|TTP36 (mouse) NOT located_in GO:0005634 nucleus MGI_ref:2652310|PMID:12606058 IDA NCBITaxon:10090 MGI:2448759 20130213 MGI:MGI PR:Q4VAA2-2 protein CDV3 isoform 2 (mouse) mCDV3/iso:2|TTP32 (mouse) located_in GO:0005737 cytoplasm MGI_ref:2652310|PMID:12606058 IDA NCBITaxon:10090 MGI:2448759 20130213 MGI:MGI PR:Q4VAA2-2 protein CDV3 isoform 2 (mouse) mCDV3/iso:2|TTP32 (mouse) NOT located_in GO:0005634 nucleus MGI_ref:2652310|PMID:12606058 IDA NCBITaxon:10090 MGI:2448759 20130213 MGI:MGI PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) enables GO:0005515 protein binding PR:O15392 BioGRID:BG-251031|IntAct:EBI-1555332|MINT:MINT-4509524 IPI NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) enables GO:0005515 protein binding PR:Q5FBB7 BioGRID:BG-452609 IPI NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) enables GO:0005515 protein binding PR:Q71DI3 BioGRID:BG-725714 IPI NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) enables GO:0005515 protein binding PR:Q96GD4 BioGRID:BG-251071 IPI NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) enables GO:0005515 protein binding PR:Q9NQS7 BioGRID:BG-251069|IntAct:EBI-1555222 IPI NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q53HL2 borealin (human) CDCA8|cell division cycle-associated protein 8 (human)|dasra-B (human)|hCDCA8|hDasra-B|PESCRG3|pluripotent embryonic stem cell-related gene 3 protein (human) located_in GO:0000779 condensed chromosome, centromeric region PMID:20929775 EXP NCBITaxon:9606 UniProtKB:Q53HL2 20130102 PRO:KER PR:Q58A65-1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 1 (mouse) JLP long (mouse)|JLPL (mouse)|mSPAG9/iso:1 enables GO:0005515 protein binding PR:Q9Z1T6 MGI_ref:3841532|PMID:19056739 IPI NCBITaxon:10090 MGI:1918084 20120817 MGI:MGI PR:Q58A65-1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 1 (mouse) JLP long (mouse)|JLPL (mouse)|mSPAG9/iso:1 located_in GO:0048471 perinuclear region of cytoplasm MGI_ref:3841532|PMID:19056739 IDA NCBITaxon:10090 MGI:1918084 20101021 MGI:MGI PR:Q58A65-2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2 (mouse) mSPAG9/iso:2 enables GO:0008432 JUN kinase binding MGI_ref:4835955|PMID:12391307 IDA NCBITaxon:10090 MGI:1918084 20101021 MGI:MGI PR:Q58A65-2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2 (mouse) mSPAG9/iso:2 enables GO:0048273 mitogen-activated protein kinase p38 binding MGI_ref:4835955|PMID:12391307 IDA NCBITaxon:10090 MGI:1918084 20101021 MGI:MGI PR:Q58A65-2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2 (mouse) mSPAG9/iso:2 acts_upstream_of_or_within GO:0007254 JNK cascade MGI_ref:4835955|PMID:12391307 IDA NCBITaxon:10090 MGI:1918084 20101021 MGI:MGI PR:Q58A65-2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2 (mouse) mSPAG9/iso:2 acts_upstream_of_or_within GO:0090074 negative regulation of protein homodimerization activity MGI_ref:4835955|PMID:12391307 IDA NCBITaxon:10090 MGI:1918084 20101021 MGI:MGI PR:Q5DQR4-2 syntaxin-binding protein 5-like isoform 2 (mouse) mSTXBP5L/iso:2|syntaxin-binding protein 5-like isoform Tomosyn-2 isoform m (mouse) enables GO:0019905 syntaxin binding MGI_ref:4948782|PMID:21330375 IDA NCBITaxon:10090 MGI:2443815 20120910 MGI:MGI PR:Q5DQR4-2 syntaxin-binding protein 5-like isoform 2 (mouse) mSTXBP5L/iso:2|syntaxin-binding protein 5-like isoform Tomosyn-2 isoform m (mouse) located_in GO:0005886 plasma membrane MGI_ref:4948782|PMID:21330375 IDA NCBITaxon:10090 MGI:2443815 20120910 MGI:MGI PR:Q5DQR4-2 syntaxin-binding protein 5-like isoform 2 (mouse) mSTXBP5L/iso:2|syntaxin-binding protein 5-like isoform Tomosyn-2 isoform m (mouse) acts_upstream_of_or_within GO:0050714 positive regulation of protein secretion MGI_ref:4948782|PMID:21330375 IDA NCBITaxon:10090 MGI:2443815 20140519 MGI:MGI PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:O60566 BioGRID:BG-723563 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:P30153 PMID:16580887 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:P53350 BioGRID:BG-338598 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:P67775 PMID:16580887 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:Q13362 PMID:16580887 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:Q53HL2 BioGRID:BG-452609 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:Q96GD4 BioGRID:BG-300525 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) enables GO:0005515 protein binding PR:Q9NQS7 BioGRID:BG-300524 IPI NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) located_in GO:0000775 chromosome, centromeric region PMID:16580887 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Timing=prophase, pro metaphase. PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) located_in GO:0000939 inner kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0007059 chromosome segregation PMID:16580887 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0007062 sister chromatid cohesion PMID:16580887 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Target=PR:P49454. PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Target=PR:P53350. PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:22732840 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Target=PR:Q96GD4. PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) NOT acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:16580887 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Target=PR:P30153. PR:Q5FBB7 shugoshin 1 (human) hSGO1|serologically defined breast cancer antigen NY-BR-85 (human)|SGO1|SGOL1|shugoshin-like 1 (human) NOT acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:16580887 EXP NCBITaxon:9606 UniProtKB:Q5FBB7 20130102 PRO:KER Target=PR:Q13362 PR:Q5SS91-1 SUN domain-containing protein 3 isoform 1 (mouse) mSUN3/iso:1 enables GO:0005515 protein binding PR:Q4FZC9 MGI_ref:4829712|PMID:20711465 IPI NCBITaxon:10090 MGI:3041199 20101123 MGI:MGI PR:Q5SWW4-1 mediator of RNA polymerase II transcription subunit 13 isoform 1 (mouse) mMED13/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:3029632 20120523 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 enables GO:0003677 DNA binding MGI_ref:3045680|PMID:15169884 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 enables GO:0005515 protein binding PR:O88491 MGI_ref:3045680|PMID:15169884 IPI NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 located_in GO:0005634 nucleus MGI_ref:3045680|PMID:15169884 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 located_in GO:0005634 nucleus MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 located_in GO:0016604 nuclear body MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-1 zinc finger protein 496 isoform 1 (mouse) mZNF496/iso:1 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3045680|PMID:15169884 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5SXI5-2 zinc finger protein 496 isoform 2 (mouse) mZNF496/iso:2 located_in GO:0005634 nucleus MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20120112 MGI:MGI PR:Q5SXI5-2 zinc finger protein 496 isoform 2 (mouse) mZNF496/iso:2 located_in GO:0016604 nuclear body MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20120112 MGI:MGI PR:Q5SXI5-3 zinc finger protein 496 isoform 3 (mouse) mZNF496/iso:3 located_in GO:0005634 nucleus MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20120112 MGI:MGI PR:Q5SXI5-3 zinc finger protein 496 isoform 3 (mouse) mZNF496/iso:3 NOT located_in GO:0016604 nuclear body MGI_ref:4837326|PMID:20538088 IDA NCBITaxon:10090 MGI:2679270 20101223 MGI:MGI PR:Q5Z9J0 mitogen-activated protein kinase 12 (rice) blast- and wound-induced MAP kinase 1 (rice)|BWMK1|LOC_Os06g49430|MAP kinase 1 (rice)|MAP kinase 12 (rice)|MAPK1|MPK12|Os06g0708000|OsBWMK1|OsMAPK1|P0621D05.40-1|P0621D05.40-2|rice-MPK12 enables GO:0004707 MAP kinase activity PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q5Z9J0 20140402 PRO:LVM PR:Q5Z9J0 mitogen-activated protein kinase 12 (rice) blast- and wound-induced MAP kinase 1 (rice)|BWMK1|LOC_Os06g49430|MAP kinase 1 (rice)|MAP kinase 12 (rice)|MAPK1|MPK12|Os06g0708000|OsBWMK1|OsMAPK1|P0621D05.40-1|P0621D05.40-2|rice-MPK12 located_in GO:0005634 nucleus PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q5Z9J0 20140402 PRO:LVM PR:Q5Z9J0 mitogen-activated protein kinase 12 (rice) blast- and wound-induced MAP kinase 1 (rice)|BWMK1|LOC_Os06g49430|MAP kinase 1 (rice)|MAP kinase 12 (rice)|MAPK1|MPK12|Os06g0708000|OsBWMK1|OsMAPK1|P0621D05.40-1|P0621D05.40-2|rice-MPK12 acts_upstream_of_or_within GO:0034052 positive regulation of plant-type hypersensitive response PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q5Z9J0 20140402 PRO:LVM, PRO:DAN PR:Q5Z9J0 mitogen-activated protein kinase 12 (rice) blast- and wound-induced MAP kinase 1 (rice)|BWMK1|LOC_Os06g49430|MAP kinase 1 (rice)|MAP kinase 12 (rice)|MAPK1|MPK12|Os06g0708000|OsBWMK1|OsMAPK1|P0621D05.40-1|P0621D05.40-2|rice-MPK12 acts_upstream_of_or_within GO:0031349 positive regulation of defense response PMID:12913152 EXP NCBITaxon:39947 UniProtKB:Q5Z9J0 20140402 PRO:LVM PR:Q60591-2 nuclear factor of activated T-cells, cytoplasmic 2 isoform 2 (mouse) mNFATC2/iso:2|NFAT1-B (mouse)|nuclear factor of activated T-cells, cytoplasmic 2 isoform B (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:81049|PMID:8668213 IDA NCBITaxon:10090 MGI:102463 20140502 MGI:MGI occurs_in(CL:0000084) PR:Q60591-3 nuclear factor of activated T-cells, cytoplasmic 2 isoform 3 (mouse) mNFATC2/iso:3|NFAT1-C (mouse)|nuclear factor of activated T-cells, cytoplasmic 2 isoform C (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:81049|PMID:8668213 IDA NCBITaxon:10090 MGI:102463 20140502 MGI:MGI occurs_in(CL:0000084) PR:Q60591-4 nuclear factor of activated T-cells, cytoplasmic 2 isoform 4 (mouse) mNFATC2/iso:4|NFAT1-D (mouse)|nuclear factor of activated T-cells, cytoplasmic 2 isoform D (mouse) enables GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding MGI_ref:2684708|PMID:11278367 IDA NCBITaxon:10090 MGI:102463 20140502 MGI:MGI PR:Q60591-4 nuclear factor of activated T-cells, cytoplasmic 2 isoform 4 (mouse) mNFATC2/iso:4|NFAT1-D (mouse)|nuclear factor of activated T-cells, cytoplasmic 2 isoform D (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:2684708|PMID:11278367 IDA NCBITaxon:10090 MGI:102463 20080109 MGI:MGI PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 enables GO:0005515 protein binding PR:Q60636-1 MGI_ref:3826899|PMID:18845144 IPI NCBITaxon:10090 UniProtKB:Q60636-1 20101014 PRO:HJD PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 enables GO:0005515 protein binding PR:Q60636-2 MGI_ref:3826899|PMID:18845144 IPI NCBITaxon:10090 UniProtKB:Q60636-1 20101014 PRO:HJD PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 enables GO:0042826 histone deacetylase binding MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 enables GO:0043565 sequence-specific DNA binding MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 located_in GO:0005634 nucleus MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 acts_upstream_of_or_within GO:0030889 negative regulation of B cell proliferation MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse) mPRDM1/iso:1 acts_upstream_of_or_within GO:0045579 positive regulation of B cell differentiation MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 enables GO:0005515 protein binding PR:Q60636-1 MGI_ref:3826899|PMID:18845144 IPI NCBITaxon:10090 UniProtKB:Q60636-2 20101014 PRO:HJD PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 enables GO:0005515 protein binding PR:Q60636-2 MGI_ref:3826899|PMID:18845144 IPI NCBITaxon:10090 UniProtKB:Q60636-2 20101014 PRO:HJD PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 enables GO:0042826 histone deacetylase binding MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20120112 MGI:MGI PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 located_in GO:0005737 cytoplasm MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI has_regulation_target(MGI:MGI:99655) PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 acts_upstream_of_or_within GO:0030889 negative regulation of B cell proliferation MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20120112 MGI:MGI PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 acts_upstream_of_or_within GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse) Blimp-1delta7 (mouse)|mPRDM1/iso:2 NOT acts_upstream_of_or_within GO:0045579 positive regulation of B cell differentiation MGI_ref:3826899|PMID:18845144 IDA NCBITaxon:10090 MGI:99655 20101013 MGI:MGI PR:Q60739-1 BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse) mBAG1/iso:BAG-1L enables GO:0005515 protein binding PR:P05627 MGI_ref:4819895|PMID:20516211 IPI NCBITaxon:10090 MGI:108047 20100825 MGI:MGI PR:Q60739-1 BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse) mBAG1/iso:BAG-1L enables GO:0051219 phosphoprotein binding PR:P05627 MGI_ref:4819895|PMID:20516211 IPI NCBITaxon:10090 MGI:108047 20100825 MGI:MGI PR:Q60739-1 BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse) mBAG1/iso:BAG-1L located_in GO:0005737 cytoplasm MGI_ref:4820775|PMID:9679980 IDA NCBITaxon:10090 MGI:108047 20101007 MGI:MGI part_of(MA:0000153) PR:Q60739-1 BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse) mBAG1/iso:BAG-1L acts_upstream_of_or_within GO:0043525 positive regulation of neuron apoptotic process MGI_ref:4819895|PMID:20516211 IDA NCBITaxon:10090 MGI:108047 20100825 MGI:MGI PR:Q60739-1 BAG family molecular chaperone regulator 1 isoform BAG-1L (mouse) mBAG1/iso:BAG-1L acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4819895|PMID:20516211 IDA NCBITaxon:10090 MGI:108047 20100825 MGI:MGI PR:Q60739-2 BAG family molecular chaperone regulator 1 isoform BAG-1 (mouse) BAG-1S (mouse)|mBAG1/iso:BAG-1 located_in GO:0005634 nucleus MGI_ref:4820775|PMID:9679980 IDA NCBITaxon:10090 MGI:108047 20140225 MGI:MGI PR:Q60739-2 BAG family molecular chaperone regulator 1 isoform BAG-1 (mouse) BAG-1S (mouse)|mBAG1/iso:BAG-1 located_in GO:0005737 cytoplasm MGI_ref:1101672|PMID:9396724 IDA NCBITaxon:10090 MGI:108047 20100825 MGI:MGI PR:Q60739-2 BAG family molecular chaperone regulator 1 isoform BAG-1 (mouse) BAG-1S (mouse)|mBAG1/iso:BAG-1 located_in GO:0005737 cytoplasm MGI_ref:4820775|PMID:9679980 IDA NCBITaxon:10090 MGI:108047 20140225 MGI:MGI PR:Q60748-2 corticotropin-releasing factor receptor 2 isoform beta (mouse) mCRHR2/iso:beta located_in GO:0009986 cell surface MGI_ref:3850921|PMID:19246489 IDA NCBITaxon:10090 MGI:894312 20101103 MGI:MGI PR:Q60748-2 corticotropin-releasing factor receptor 2 isoform beta (mouse) mCRHR2/iso:beta acts_upstream_of_or_within GO:0043950 positive regulation of cAMP-mediated signaling PMID:19246489 EXP NCBITaxon:10090 UniProtKB:Q60748-2 20101103 PRO:HJD PR:Q60819-1 interleukin-15 receptor subunit alpha isoform 1 (mouse) mIL15RA/iso:1 located_in GO:0005886 plasma membrane MGI_ref:4461380|PMID:20374432 IDA NCBITaxon:10090 MGI:104644 20130610 MGI:MGI PR:Q60954-1 homeobox protein Meis1 isoform 1 (mouse) homeobox protein Meis1 isoform Meis1A (mouse)|mMEIS1/iso:1 enables GO:0005515 protein binding PR:O35317-1 MGI_ref:3505657|PMID:15466398 IPI NCBITaxon:10090 MGI:104717 20080829 MGI:MGI PR:Q60954-1 homeobox protein Meis1 isoform 1 (mouse) homeobox protein Meis1 isoform Meis1A (mouse)|mMEIS1/iso:1 enables GO:0005515 protein binding PR:O35317-1 MGI_ref:3697248|PMID:17056599 IPI NCBITaxon:10090 MGI:104717 20080829 MGI:MGI PR:Q60954-1 homeobox protein Meis1 isoform 1 (mouse) homeobox protein Meis1 isoform Meis1A (mouse)|mMEIS1/iso:1 enables GO:0005515 protein binding PR:Q62424 MGI_ref:3527920|PMID:15617687 IPI NCBITaxon:10090 MGI:104717 20080829 MGI:MGI PR:Q60954-2 homeobox protein Meis1 isoform 2 (mouse) homeobox protein Meis1 isoform Meis1B (mouse)|mMeis1/iso:2 enables GO:0005515 protein binding PR:Q62424 MGI_ref:3527920|PMID:15617687 IPI NCBITaxon:10090 MGI:104717 20140502 MGI:MGI PR:Q61144-2 presenilin-2 isoform PS2beta (mouse) mPSEN2/iso:PS2beta located_in GO:0005783 endoplasmic reticulum MGI_ref:3843380|PMID:19376115 IDA NCBITaxon:10090 MGI:109284 20130628 MGI:MGI part_of(MA:0000168) PR:Q61144-2 presenilin-2 isoform PS2beta (mouse) mPSEN2/iso:PS2beta acts_upstream_of_or_within GO:0031333 negative regulation of protein-containing complex assembly MGI_ref:3843380|PMID:19376115 IDA NCBITaxon:10090 MGI:109284 20130701 MGI:MGI PR:Q61144-2 presenilin-2 isoform PS2beta (mouse) mPSEN2/iso:PS2beta acts_upstream_of_or_within GO:0032091 negative regulation of protein binding MGI_ref:3843380|PMID:19376115 IDA NCBITaxon:10090 MGI:109284 20130701 MGI:MGI PR:Q61288-1 serine/threonine-protein kinase receptor R3 isoform 1 (mouse) mACVRL1/iso:1 enables GO:0046332 SMAD binding PMID:14580334 IDA NCBITaxon:10090 UniProtKB:Q61288-1 20080301 PRO:CNA PR:Q61288-1 serine/threonine-protein kinase receptor R3 isoform 1 (mouse) mACVRL1/iso:1 acts_upstream_of_or_within GO:0001525 angiogenesis PMID:10716993 IDA NCBITaxon:10090 UniProtKB:Q61288-1 20080301 PRO:CNA PR:Q61288-1 serine/threonine-protein kinase receptor R3 isoform 1 (mouse) mACVRL1/iso:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:14580334 IDA NCBITaxon:10090 UniProtKB:Q61288-1 20080301 PRO:CNA PR:Q61288-1 serine/threonine-protein kinase receptor R3 isoform 1 (mouse) mACVRL1/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:14580334 IDA NCBITaxon:10090 UniProtKB:Q61288-1 20080301 PRO:CNA PR:Q61527 receptor tyrosine-protein kinase erbB-4 (mouse) Erbb4|Mer4|mERBB4|proto-oncogene-like protein c-ErbB-4 (mouse) acts_upstream_of_or_within GO:2001223 negative regulation of neuron migration MGI_ref:5320808|PMID:22376909 IMP NCBITaxon:10090 MGI_allele:1929607 MGI:104771 20150701 MGI:MGI PR:Q61584-1 RNA-binding protein FXR1 isoform E (mouse) mFXR1/iso:E enables GO:0002151 G-quadruplex RNA binding MGI_ref:3699977|PMID:17170008 IDA NCBITaxon:10090 MGI:104860 20091026 MGI:MGI PR:Q61584-1 RNA-binding protein FXR1 isoform E (mouse) mFXR1/iso:E located_in GO:0005634 nucleus PMID:11178106 EXP NCBITaxon:10090 UniProtKB:Q61584-1 20091027 PRO:HJD PR:Q61584-1 RNA-binding protein FXR1 isoform E (mouse) mFXR1/iso:E located_in GO:0005737 cytoplasm MGI_ref:3760313|PMID:11178106 IDA NCBITaxon:10090 MGI:104860 20091027 MGI:MGI part_of(CL:0000188) PR:Q61584-1 RNA-binding protein FXR1 isoform E (mouse) mFXR1/iso:E part_of GO:0005840 ribosome MGI_ref:3760313|PMID:11178106 IDA NCBITaxon:10090 MGI:104860 20091027 MGI:MGI part_of(CL:0000188) PR:Q61584-1 RNA-binding protein FXR1 isoform E (mouse) mFXR1/iso:E part_of GO:0043034 costamere PMID:15128702 EXP NCBITaxon:10090 UniProtKB:Q61584-1 20091027 PRO:HJD PR:Q61584-2 RNA-binding protein FXR1 isoform A (mouse) mFXR1/iso:A NOT enables GO:0002151 G-quadruplex RNA binding MGI_ref:3699977|PMID:17170008 IDA NCBITaxon:10090 MGI:104860 20091026 MGI:MGI PR:Q61584-5 RNA-binding protein FXR1 isoform D (mouse) mFXR1/iso:D enables GO:0003730 mRNA 3'-UTR binding MGI_ref:3573966|PMID:15548538 IDA NCBITaxon:10090 MGI:104860 20091019 MGI:MGI PR:Q61584-5 RNA-binding protein FXR1 isoform D (mouse) mFXR1/iso:D located_in GO:0005737 cytoplasm MGI_ref:3573966|PMID:15548538 IDA NCBITaxon:10090 MGI:104860 20091019 MGI:MGI PR:Q61584-5 RNA-binding protein FXR1 isoform D (mouse) mFXR1/iso:D acts_upstream_of_or_within GO:0017148 negative regulation of translation MGI_ref:3573966|PMID:15548538 IDA NCBITaxon:10090 MGI:104860 20091019 MGI:MGI PR:Q61584-5 RNA-binding protein FXR1 isoform D (mouse) mFXR1/iso:D NOT enables GO:0002151 G-quadruplex RNA binding MGI_ref:3699977|PMID:17170008 IDA NCBITaxon:10090 MGI:104860 20111216 MGI:MGI PR:Q61584-6 RNA-binding protein FXR1 isoform F (mouse) mFXR1/iso:F located_in GO:0005634 nucleus PMID:11178106 EXP NCBITaxon:10090 UniProtKB:Q61584-6 20091027 PRO:HJD PR:Q61584-6 RNA-binding protein FXR1 isoform F (mouse) mFXR1/iso:F located_in GO:0005737 cytoplasm PMID:11178106 EXP NCBITaxon:10090 UniProtKB:Q61584-6 20091027 PRO:HJD PR:Q61584-6 RNA-binding protein FXR1 isoform F (mouse) mFXR1/iso:F part_of GO:0005840 ribosome PMID:11178106 EXP NCBITaxon:10090 UniProtKB:Q61584-6 20091027 PRO:HJD PR:Q61584-7 RNA-binding protein FXR1 isoform G (mouse) mFXR1/iso:G located_in GO:0005634 nucleus PMID:11178106 EXP NCBITaxon:10090 UniProtKB:Q61584-7 20091027 PRO:HJD PR:Q61584-7 RNA-binding protein FXR1 isoform G (mouse) mFXR1/iso:G located_in GO:0005737 cytoplasm MGI_ref:3760313|PMID:11178106 IDA NCBITaxon:10090 MGI:104860 20140401 MGI:MGI part_of(CL:0000188) PR:Q61584-7 RNA-binding protein FXR1 isoform G (mouse) mFXR1/iso:G part_of GO:0005840 ribosome MGI_ref:3760313|PMID:11178106 IDA NCBITaxon:10090 MGI:104860 20140401 MGI:MGI part_of(CL:0000188) PR:Q61699-1 heat shock protein 105 kDa isoform HSP105-alpha (mouse) mHSPH1/iso:HSP105-alpha located_in GO:0005737 cytoplasm MGI_ref:5607133|PMID:17643418 IDA NCBITaxon:10090 MGI:105053 20141216 MGI:MGI PR:Q61699-1 heat shock protein 105 kDa isoform HSP105-alpha (mouse) mHSPH1/iso:HSP105-alpha acts_upstream_of_or_within GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI_ref:3688933|PMID:16857185 IMP NCBITaxon:10090 MGI:105053 20141222 MGI:MGI transports_or_maintains_localization_of(UniProtKB:Q07812) PR:Q61699-1 heat shock protein 105 kDa isoform HSP105-alpha (mouse) mHSPH1/iso:HSP105-alpha acts_upstream_of_or_within GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI_ref:3822965|PMID:18681888 IMP NCBITaxon:10090 MGI:105053 20141222 MGI:MGI PR:Q61699-1 heat shock protein 105 kDa isoform HSP105-alpha (mouse) mHSPH1/iso:HSP105-alpha acts_upstream_of_or_within GO:1903753 negative regulation of p38MAPK cascade MGI_ref:3822965|PMID:18681888 IGI NCBITaxon:10090 MGI:1346865 MGI:105053 20141222 MGI:MGI PR:Q61699-1 heat shock protein 105 kDa isoform HSP105-alpha (mouse) mHSPH1/iso:HSP105-alpha acts_upstream_of_or_within GO:2001234 negative regulation of apoptotic signaling pathway MGI_ref:3688933|PMID:16857185 IMP NCBITaxon:10090 MGI:105053 20141212 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta located_in GO:0005634 nucleus MGI_ref:4422145|PMID:19754877 IDA NCBITaxon:10090 MGI:105053 20141219 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta located_in GO:0005634 nucleus MGI_ref:5607132|PMID:19028714 IDA NCBITaxon:10090 MGI:105053 20141216 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta located_in GO:0005634 nucleus MGI_ref:5607133|PMID:17643418 IDA NCBITaxon:10090 MGI:105053 20141216 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4422145|PMID:19754877 IDA NCBITaxon:10090 MGI:105053 20141219 MGI:MGI regulates_o_has_output(UniProtKB:P08107) PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4422145|PMID:19754877 IGI NCBITaxon:10090 UniProtKB:P40763 MGI:105053 20141219 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:5607132|PMID:19028714 IDA NCBITaxon:10090 MGI:105053 20141216 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:0061098 positive regulation of protein tyrosine kinase activity MGI_ref:4422145|PMID:19754877 IDA NCBITaxon:10090 MGI:105053 20141219 MGI:MGI has_direct_input(UniProtKB:P40763) PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI_ref:3688933|PMID:16857185 IMP NCBITaxon:10090 MGI:105053 20141222 MGI:MGI transports_or_maintains_localization_of(UniProtKB:Q07812) PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI_ref:3822965|PMID:18681888 IMP NCBITaxon:10090 MGI:105053 20141222 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:1903753 negative regulation of p38MAPK cascade MGI_ref:3822965|PMID:18681888 IGI NCBITaxon:10090 MGI:1346865 MGI:105053 20141222 MGI:MGI PR:Q61699-2 heat shock protein 105 kDa isoform HSP105-beta (mouse) mHSPH1/iso:HSP105-beta acts_upstream_of_or_within GO:2001234 negative regulation of apoptotic signaling pathway MGI_ref:3688933|PMID:16857185 IMP NCBITaxon:10090 MGI:105053 20141212 MGI:MGI PR:Q61739-2 integrin alpha-6 isoform Alpha-6X1A (mouse) mITGA6/iso:Alpha-6X1A enables GO:0005178 integrin binding PR:P09055 MGI_ref:75849|PMID:1833411 IPI NCBITaxon:10090 MGI:96605 20071219 MGI:MGI PR:Q61739-2 integrin alpha-6 isoform Alpha-6X1A (mouse) mITGA6/iso:Alpha-6X1A located_in GO:0009986 cell surface MGI_ref:75849|PMID:1833411 IDA NCBITaxon:10090 MGI:96605 20071219 MGI:MGI PR:Q61739-2 integrin alpha-6 isoform Alpha-6X1A (mouse) mITGA6/iso:Alpha-6X1A acts_upstream_of_or_within GO:0033627 cell adhesion mediated by integrin MGI_ref:75849|PMID:1833411 IDA NCBITaxon:10090 MGI:96605 20071219 MGI:MGI PR:Q61762-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse) mKCNA5/iso:1 enables GO:0005249 voltage-gated potassium channel activity MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20071218 MGI:MGI PR:Q61762-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse) mKCNA5/iso:1 located_in GO:0005886 plasma membrane MGI_ref:63618|PMID:8226976 IC NCBITaxon:10090 GO:0005249 MGI:96662 20071218 MGI:MGI PR:Q61762-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse) mKCNA5/iso:1 acts_upstream_of_or_within GO:0006813 potassium ion transport MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20071218 MGI:MGI PR:Q61762-2 potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse) mKCNA5/iso:2|potassium voltage-gated channel subfamily A member 5 isoform 5' (mouse) enables GO:0005249 voltage-gated potassium channel activity MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20120126 MGI:MGI PR:Q61762-2 potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse) mKCNA5/iso:2|potassium voltage-gated channel subfamily A member 5 isoform 5' (mouse) located_in GO:0005886 plasma membrane MGI_ref:63618|PMID:8226976 IC NCBITaxon:10090 GO:0005249 MGI:96662 20140425 MGI:MGI PR:Q61762-2 potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse) mKCNA5/iso:2|potassium voltage-gated channel subfamily A member 5 isoform 5' (mouse) acts_upstream_of_or_within GO:0006813 potassium ion transport MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20120126 MGI:MGI PR:Q61762-3 potassium voltage-gated channel subfamily A member 5 isoform 3 (mouse) mKCNA5/iso:3|potassium voltage-gated channel subfamily A member 5 isoform 3' (mouse) enables GO:0019870 potassium channel inhibitor activity MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20071218 MGI:MGI PR:Q61762-3 potassium voltage-gated channel subfamily A member 5 isoform 3 (mouse) mKCNA5/iso:3|potassium voltage-gated channel subfamily A member 5 isoform 3' (mouse) acts_upstream_of_or_within GO:0043267 negative regulation of potassium ion transport MGI_ref:63618|PMID:8226976 IDA NCBITaxon:10090 MGI:96662 20071218 MGI:MGI PR:Q61985-3 endoplasmic reticulum membrane sensor NFE2L1 isoform Nrf1b (mouse) mNFE2L1/iso:2|Nrf1b (mouse)|nuclear factor erythroid 2-related factor 1 isoform 2 (mouse) located_in GO:0005634 nucleus MGI_ref:5464962|PMID:23144760 IDA NCBITaxon:10090 MGI:99421 20130329 MGI:MGI PR:Q61985-3 endoplasmic reticulum membrane sensor NFE2L1 isoform Nrf1b (mouse) mNFE2L1/iso:2|Nrf1b (mouse)|nuclear factor erythroid 2-related factor 1 isoform 2 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:5464962|PMID:23144760 IDA NCBITaxon:10090 MGI:99421 20130329 MGI:MGI PR:Q62312-1 TGF-beta receptor type-2 isoform RII-2 (mouse) mTGFBR2/iso:RII-2 enables GO:0050431 transforming growth factor beta binding PMID:7957954 EXP NCBITaxon:10090 UniProtKB:Q62312-1 20150309 PRO:CNA PR:Q62312-1 TGF-beta receptor type-2 isoform RII-2 (mouse) mTGFBR2/iso:RII-2 located_in GO:0016020 membrane PMID:7959019 EXP NCBITaxon:10090 UniProtKB:Q62312-1 20150309 PRO:CNA PR:Q62312-2 TGF-beta receptor type-2 isoform RII-1 (mouse) mTGFBR2/iso:RII-1 located_in GO:0016020 membrane PMID:7957954 EXP NCBITaxon:10090 UniProtKB:Q62312-2 20150309 PRO:CNA PR:Q62398 cyclic nucleotide-gated olfactory channel (mouse) Cncg2|Cncg4|CNG channel alpha-2 (mouse)|CNG-2 (mouse)|CNG2 (mouse)|Cnga2|cyclic nucleotide-gated cation channel 2 (mouse)|cyclic nucleotide-gated channel alpha-2 (mouse)|mCNGA2 enables GO:0005216 monoatomic ion channel activity PMID:10798394 IDA NCBITaxon:10090 UniProtKB:Q62398 20080601 PRO:CNA PR:Q62398 cyclic nucleotide-gated olfactory channel (mouse) Cncg2|Cncg4|CNG channel alpha-2 (mouse)|CNG-2 (mouse)|CNG2 (mouse)|Cnga2|cyclic nucleotide-gated cation channel 2 (mouse)|cyclic nucleotide-gated channel alpha-2 (mouse)|mCNGA2 acts_upstream_of_or_within GO:0007608 sensory perception of smell PMID:10798394 IDA NCBITaxon:10090 UniProtKB:Q62398 20080601 PRO:CNA PR:Q62432-1 mothers against decapentaplegic homolog 2 isoform Long (mouse) mSMAD2/iso:Long located_in GO:0005737 cytoplasm PMID:14701940 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:Q62432-1 mothers against decapentaplegic homolog 2 isoform Long (mouse) mSMAD2/iso:Long acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11557747 IDA NCBITaxon:10090 UniProtKB:Q62432-1 20080301 PRO:CNA PR:Q63844-1 mitogen-activated protein kinase 3 isoform 1 (mouse) mMAPK3/iso:1 enables GO:0005515 protein binding PR:Q9DAJ4 PMID:15118098 IPI NCBITaxon:10090 UniProtKB:Q63844-1 20091115 PRO:CNA PR:Q63844-1 mitogen-activated protein kinase 3 isoform 1 (mouse) mMAPK3/iso:1 located_in GO:0005737 cytoplasm PMID:11726647|PMID:12223545 IDA NCBITaxon:10090 UniProtKB:Q63844-1 20091115 PRO:CNA PR:Q64280-1 left-right determination factor 1 isoform 1 (mouse) mLEFTY1/iso:1 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15004567 IDA NCBITaxon:10090 UniProtKB:Q64280-1 20080301 PRO:CNA PR:Q64280-1 left-right determination factor 1 isoform 1 (mouse) mLEFTY1/iso:1 acts_upstream_of_or_within GO:0009948 anterior/posterior axis specification PMID:15004567 IDA NCBITaxon:10090 UniProtKB:Q64280-1 20080301 PRO:CNA PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse) Bcl-2-like protein 1 isoform Bcl-xL (mouse)|mBCL2L1/iso:Bcl-X(L) associated_with_disease_progression DOID:162 cancer PMID:16403219 EXP NCBITaxon:10090 UniProtKB:Q64373-1 20140718 PRO:KER PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse) Bcl-2-like protein 1 isoform Bcl-xL (mouse)|mBCL2L1/iso:Bcl-X(L) enables GO:0005515 protein binding PR:O08734 MGI_ref:3804133|PMID:16705087 IPI NCBITaxon:10090 MGI:88139 20120903 MGI:MGI PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse) Bcl-2-like protein 1 isoform Bcl-xL (mouse)|mBCL2L1/iso:Bcl-X(L) enables GO:0046982 protein heterodimerization activity PR:Q07813 MGI_ref:82784|PMID:8798452 IPI NCBITaxon:10090 MGI:88139 20081223 MGI:MGI PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse) Bcl-2-like protein 1 isoform Bcl-xL (mouse)|mBCL2L1/iso:Bcl-X(L) acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:69011|PMID:7607090 IDA NCBITaxon:10090 MGI:88139 20080205 MGI:MGI PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse) Bcl-2-like protein 1 isoform Bcl-xL (mouse)|mBCL2L1/iso:Bcl-X(L) acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:81233|PMID:8798158 IDA NCBITaxon:10090 MGI:88139 20090128 MGI:MGI PR:Q64373-2 Bcl-2-like protein 1 isoform Bcl-X(S) (mouse) Bcl-2-like protein 1 isoform Bcl-xS (mouse)|mBCL2L1/iso:Bcl-X(S) acts_upstream_of_or_within GO:0043065 positive regulation of apoptotic process MGI_ref:81233|PMID:8798158 IDA NCBITaxon:10090 MGI:88139 20090128 MGI:MGI PR:Q64516-1 glycerol kinase isoform 1 (mouse) mGK/iso:1 located_in GO:0005739 mitochondrion MGI_ref:3575881|PMID:15845384 IDA NCBITaxon:10090 MGI:106594 20140327 MGI:MGI PR:Q64516-2 glycerol kinase isoform 2 (mouse) mGK/iso:2 enables GO:0004370 glycerol kinase activity MGI_ref:3575881|PMID:15845384 IDA NCBITaxon:10090 MGI:106594 20131217 MGI:MGI PR:Q64516-2 glycerol kinase isoform 2 (mouse) mGK/iso:2 located_in GO:0005634 nucleus MGI_ref:3575881|PMID:15845384 IDA NCBITaxon:10090 MGI:106594 20131217 MGI:MGI PR:Q64516-2 glycerol kinase isoform 2 (mouse) mGK/iso:2 located_in GO:0005739 mitochondrion MGI_ref:3575881|PMID:15845384 IDA NCBITaxon:10090 MGI:106594 20131217 MGI:MGI PR:Q64516-2 glycerol kinase isoform 2 (mouse) mGK/iso:2 located_in GO:0005829 cytosol MGI_ref:3575881|PMID:15845384 IDA NCBITaxon:10090 MGI:106594 20131217 MGI:MGI PR:Q64700-1 retinoblastoma-like protein 2 isoform 1 (mouse) mRBL2/iso:1 enables GO:0030308 negative regulation of cell growth PMID:10082561 IDA NCBITaxon:10090 UniProtKB:Q64700-1 20080301 PRO:CNA PR:Q64700-1 retinoblastoma-like protein 2 isoform 1 (mouse) mRBL2/iso:1 located_in GO:0005634 nucleus PMID:10082561 IDA NCBITaxon:10090 UniProtKB:Q64700-1 20080301 PRO:CNA PR:Q64700-1 retinoblastoma-like protein 2 isoform 1 (mouse) mRBL2/iso:1 acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:10082561 IDA NCBITaxon:10090 UniProtKB:Q64700-1 20080301 PRO:CNA PR:Q69ZI1-1 E3 ubiquitin-protein ligase SH3RF1 isoform 1 (mouse) mSH3RF1/iso:1 enables GO:0005515 protein binding PR:000025641 PMID:16230351 IPI NCBITaxon:10090 UniProtKB:Q69ZI1-1 20100515 PRO:CNA PR:Q69ZI1-1 E3 ubiquitin-protein ligase SH3RF1 isoform 1 (mouse) mSH3RF1/iso:1 enables GO:0005515 protein binding PR:Q8IUQ4 PMID:16230351 IPI NCBITaxon:10090 UniProtKB:Q69ZI1-1 20100515 PRO:CNA PR:Q6DR98 pro-neuregulin-1, membrane-bound isoform (mouse) mNRG1/iso:Ibeta1a|NRG beta1 (mouse) located_in GO:0009897 external side of plasma membrane MGI_ref:3625788|PMID:11116142 IDA NCBITaxon:10090 MGI:96083 20150514 MGI:MGI part_of(CL:0000187) PR:Q6DR98 pro-neuregulin-1, membrane-bound isoform (mouse) mNRG1/iso:Ibeta1a|NRG beta1 (mouse) NOT acts_upstream_of_or_within GO:0031643 positive regulation of myelination MGI_ref:3042336|PMID:15044753 IMP NCBITaxon:10090 MGI_allele:1928489 MGI:96083 20150611 MGI:MGI occurs_in(CL:0000540),occurs_in(MA:0001172) PR:Q6DR99 neuregulin-1 type III-beta1a (mouse) mNRG1|protein Nrg1 (mouse) acts_upstream_of_or_within GO:0031643 positive regulation of myelination MGI_ref:3042336|PMID:15044753 IMP NCBITaxon:10090 MGI_allele:1928489 MGI:96083 20150611 MGI:MGI occurs_in(CL:0000540),occurs_in(MA:0001172) PR:Q6KAQ7-1 ZZ-type zinc finger-containing protein 3 isoform 1 (mouse) mZZZ3/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1920453 20120611 MGI:MGI PR:Q6LC96 retinoic acid receptor RXR-alpha isoform 2 (mouse) mRXRA/iso:2|RXR-alpha2 (mouse)|RXR-alpha2/3 (mouse)|RXR-alpha3 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:85343|PMID:8954108 IDA NCBITaxon:10090 MGI:98214 20140606 MGI:MGI has_input(CHEBI:50648) PR:Q6NS45-1 coiled-coil domain-containing protein 66 isoform 1 (mouse) mCCDC66/iso:1 acts_upstream_of_or_within GO:0046548 retinal rod cell development MGI_ref:5141557|PMID:21680557 IMP NCBITaxon:10090 MGI_allele:3893603 MGI:2443639 20121207 MGI:MGI occurs_in(MA:0002472),results_in_development_of(CL:0000604) PR:Q6NS45-1 coiled-coil domain-containing protein 66 isoform 1 (mouse) mCCDC66/iso:1 acts_upstream_of_or_within GO:0060060 post-embryonic retina morphogenesis in camera-type eye MGI_ref:5141557|PMID:21680557 IMP NCBITaxon:10090 MGI_allele:3893603 MGI:2443639 20121207 MGI:MGI has_participant(MA:0002472) PR:Q6P4T1 sorting nexin-19 (mouse) Kiaa0254|mSNX19|Snx19 located_in GO:0031901 early endosome membrane MGI_ref:5605376|PMID:25148684 IDA NCBITaxon:10090 MGI:1921581 20141201 MGI:MGI PR:Q6PGF3-1 mediator of RNA polymerase II transcription subunit 16 isoform 1 (mouse) mMED16/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:2158394 20120523 MGI:MGI PR:Q6PHZ2 calcium/calmodulin-dependent protein kinase type II subunit delta (mouse) CaM kinase II subunit delta (mouse)|CaMK-II subunit delta (mouse)|Camk2d|Kiaa4163|mCAMK2D located_in GO:0005634 nucleus MGI_ref:5466245|PMID:21998325 IDA NCBITaxon:10090 MGI:1341265 20140715 MGI:MGI part_of(MA:0000091),part_of(CL:0000746) PR:Q6PHZ2 calcium/calmodulin-dependent protein kinase type II subunit delta (mouse) CaM kinase II subunit delta (mouse)|CaMK-II subunit delta (mouse)|Camk2d|Kiaa4163|mCAMK2D located_in GO:0016529 sarcoplasmic reticulum MGI_ref:5466245|PMID:21998325 IDA NCBITaxon:10090 MGI:1341265 20140715 MGI:MGI part_of(MA:0000091),part_of(CL:0000746) PR:Q6PHZ2-1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1 (mouse) calcium/calmodulin-dependent protein kinase type II subunit delta isoform delta 2 (mouse)|mCAMK2D/iso:1 located_in GO:0005634 nucleus MGI_ref:5466245|PMID:21998325 IDA NCBITaxon:10090 MGI:1341265 20140715 MGI:MGI part_of(MA:0000091),part_of(CL:0000746) PR:Q6PHZ2-1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1 (mouse) calcium/calmodulin-dependent protein kinase type II subunit delta isoform delta 2 (mouse)|mCAMK2D/iso:1 located_in GO:0016529 sarcoplasmic reticulum MGI_ref:5466245|PMID:21998325 IDA NCBITaxon:10090 MGI:1341265 20140715 MGI:MGI part_of(MA:0000091),part_of(CL:0000746) PR:Q6ZPK0-3 PHD finger protein 21A isoform 3 (mouse) mPHF21A/iso:3|PHD finger protein 21A isoform BHC80-6(AIF2+5) (mouse) located_in GO:0005634 nucleus MGI_ref:3051428|PMID:15325272 IDA NCBITaxon:10090 MGI:2384756 20140502 MGI:MGI part_of(MA:0000993),part_of(CL:0000117) PR:Q700C7 transcription factor SPEECHLESS (Arabidopsis thaliana) At-SPCH|At5g53210|AtbHLH98|basic helix-loop-helix protein 98 (Arabidopsis thaliana)|bHLH 98 (Arabidopsis thaliana)|bHLH transcription factor bHLH098 (Arabidopsis thaliana)|BHLH98|EN19|MFH8.15|SPCH|transcription factor EN 19 (Arabidopsis thaliana) located_in GO:0005634 nucleus PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7 20140402 PRO:LVM PR:Q700C7 transcription factor SPEECHLESS (Arabidopsis thaliana) At-SPCH|At5g53210|AtbHLH98|basic helix-loop-helix protein 98 (Arabidopsis thaliana)|bHLH 98 (Arabidopsis thaliana)|bHLH transcription factor bHLH098 (Arabidopsis thaliana)|BHLH98|EN19|MFH8.15|SPCH|transcription factor EN 19 (Arabidopsis thaliana) acts_upstream_of_or_within GO:2000037 regulation of stomatal complex patterning PMID:19008449 EXP NCBITaxon:3702 UniProtKB:Q700C7 20140402 PRO:LVM PR:Q704Y3-1 transient receptor potential cation channel subfamily V member 1 isoform 1 (mouse) mTRPV1/iso:1|transient receptor potential cation channel subfamily V member 1 isoform Alpha (mouse) enables GO:0005216 monoatomic ion channel activity MGI_ref:3053490|PMID:15194687 IDA NCBITaxon:10090 MGI:1341787 20081031 MGI:MGI PR:Q71UK2 carbonic anhydrase 6 isoform 2 (mouse) mCA6/iso:2|mouse stress-inducible intra-cellular carbonic anhydrase isozyme VI located_in GO:0005737 cytoplasm PMID:9858573 EXP NCBITaxon:10090 UniProtKB:Q71UK2 20110617 PRO:HJD PR:Q76LL6-1 FH1/FH2 domain-containing protein 3 isoform FHOS2L (mouse) Fhod3 isoform 1 (mouse)|FHOS2L (mouse)|mFHOD3/iso:FHOS2L located_in GO:0030017 sarcomere MGI_ref:5440634|PMID:22509354 IDA NCBITaxon:10090 MGI:1925847 20130418 MGI:MGI part_of(MA:0000072) PR:Q76LL6-1 FH1/FH2 domain-containing protein 3 isoform FHOS2L (mouse) Fhod3 isoform 1 (mouse)|FHOS2L (mouse)|mFHOD3/iso:FHOS2L acts_upstream_of_or_within GO:0051639 actin filament network formation MGI_ref:5440634|PMID:22509354 IDA NCBITaxon:10090 MGI:1925847 20130418 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) enables GO:0005385 zinc ion transmembrane transporter activity MGI_ref:2684332|PMID:12801924 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) enables GO:0005385 zinc ion transmembrane transporter activity MGI_ref:3028750|PMID:14612438 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) located_in GO:0005768 endosome MGI_ref:3028750|PMID:14612438 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) located_in GO:0005886 plasma membrane MGI_ref:3028750|PMID:14612438 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) located_in GO:0016324 apical plasma membrane MGI_ref:2684332|PMID:12801924 IDA NCBITaxon:10090 MGI:1919277 20090410 MGI:MGI part_of(MA:0000337),part_of(CL:0000584) PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) located_in GO:0031410 cytoplasmic vesicle MGI_ref:3028750|PMID:14612438 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q78IQ7-1 zinc transporter ZIP4 isoform 1 (mouse) mSLC39A4/iso:1|zinc transporter ZIP4 isoform Long (mouse) acts_upstream_of_or_within GO:0006882 intracellular zinc ion homeostasis MGI_ref:3028750|PMID:14612438 IDA NCBITaxon:10090 MGI:1919277 20080324 MGI:MGI PR:Q7TN02-1 mediator of RNA polymerase II transcription subunit 26 isoform 1 (mouse) mMED26/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1917875 20120523 MGI:MGI PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) enables GO:0003682 chromatin binding MGI_ref:3701709|PMID:16893423 IDA NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI has_participant(MGI:MGI:1097153) PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) located_in GO:0005634 nucleus MGI_ref:3701709|PMID:16893423 IDA NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) acts_upstream_of_or_within GO:0021516 dorsal spinal cord development MGI_ref:2669568|PMID:12925582 IMP NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI results_in_development_of(EMAP:4260) PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) acts_upstream_of_or_within GO:0021696 cerebellar cortex morphogenesis MGI_ref:2669568|PMID:12925582 IMP NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI has_participant(EMAP:4176) PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) acts_upstream_of_or_within GO:0030900 forebrain development MGI_ref:2669568|PMID:12925582 IMP NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI results_in_development_of(EMAP:4170) PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) acts_upstream_of_or_within GO:0030901 midbrain development MGI_ref:2669568|PMID:12925582 IMP NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI results_in_development_of(EMAP:4226) PR:Q7TNK1-1 transcription factor RFX4 isoform 1 (mouse) mRFX4/iso:1|transcription factor RFX4 isoform bRFX4 (mouse)|transcription factor RFX4 isoform RFX4_v3 (mouse) acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3701709|PMID:16893423 IDA NCBITaxon:10090 MGI:1918387 20080222 MGI:MGI has_regulation_target(MGI:MGI:1097153) PR:Q7TNV1-1 ceramide synthase isoform 1 (mouse) mFAM57B/iso:1 located_in GO:0005794 Golgi apparatus MGI_ref:5490837|PMID:23275342 IDA NCBITaxon:10090 MGI:97363 MGI:1916202 20131023 MGI:MGI PR:Q7TNV1-1 ceramide synthase isoform 1 (mouse) mFAM57B/iso:1 acts_upstream_of_or_within GO:0008284 positive regulation of cell population proliferation MGI_ref:4940967|PMID:19745830 IDA NCBITaxon:10090 MGI:109127 20110412 MGI:MGI PR:Q7TNV1-1 ceramide synthase isoform 1 (mouse) mFAM57B/iso:1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process MGI_ref:4940967|PMID:19745830 IDA NCBITaxon:10090 MGI:109127 20110412 MGI:MGI PR:Q7TNV1-2 ceramide synthase isoform 2 (mouse) mFAM57B/iso:2 located_in GO:0005783 endoplasmic reticulum MGI_ref:5490837|PMID:23275342 IDA NCBITaxon:10090 MGI:1336991 MGI:1916202 20131023 MGI:MGI PR:Q7TNV1-3 ceramide synthase isoform 3 (mouse) mFAM57B/iso:3 located_in GO:0005783 endoplasmic reticulum MGI_ref:5490837|PMID:23275342 IDA NCBITaxon:10090 MGI:97363 MGI:1916202 20140326 MGI:MGI PR:Q7TSD4-6 protein SPATIAL isoform 6 (mouse) mTBATA/iso:6|Spatial long (mouse) located_in GO:0005634 nucleus MGI_ref:3607210|PMID:11196687 IDA NCBITaxon:10090 MGI:1923820 20070928 MGI:MGI PR:Q7TSD4-7 protein SPATIAL isoform 7 (mouse) mTBATA/iso:7|Spatial short (mouse) located_in GO:0005634 nucleus MGI_ref:3607210|PMID:11196687 IDA NCBITaxon:10090 MGI:1923820 20111216 MGI:MGI PR:Q7TSK2-1 seizure protein 6 isoform 1 (mouse) mSEZ6/iso:1|seizure protein 6 type 2 (mouse) acts_upstream_of_or_within GO:2000171 negative regulation of dendrite development MGI_ref:3776726|PMID:18031681 IDA NCBITaxon:10090 MGI:104745 20120109 MGI:MGI PR:Q7TSK2-3 seizure protein 6 isoform 3 (mouse) mSEZ6/iso:3|seizure protein 6 type 3 (mouse) located_in GO:0005615 extracellular space MGI_ref:3776726|PMID:18031681 IDA NCBITaxon:10090 MGI:104745 20120109 MGI:MGI PR:Q7TSK2-3 seizure protein 6 isoform 3 (mouse) mSEZ6/iso:3|seizure protein 6 type 3 (mouse) acts_upstream_of_or_within GO:1900006 positive regulation of dendrite development MGI_ref:3776726|PMID:18031681 IDA NCBITaxon:10090 MGI:104745 20120118 MGI:MGI PR:Q800D4 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (chicken) BubR1|chick-BUB1B located_in GO:0000776 kinetochore PMID:17276342 EXP NCBITaxon:9031 MGI:1350695|PMID:10601341 UniProtKB:Q800D4 20130102 PRO:KER Timing=spindle depolymerization (nocodazole) and lack of kinetochore tension (taxol). PR:Q80UW0-3 heparan-sulfate 6-O-sulfotransferase 2 isoform 3 (mouse) mHS6ST2/iso:3 enables GO:0017095 heparan sulfate 6-O-sulfotransferase activity MGI_ref:1353793|PMID:10644753 IDA NCBITaxon:10090 MGI:1354959 20130904 MGI:MGI PR:Q80UW0-3 heparan-sulfate 6-O-sulfotransferase 2 isoform 3 (mouse) mHS6ST2/iso:3 acts_upstream_of_or_within GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification MGI_ref:1353793|PMID:10644753 IDA NCBITaxon:10090 MGI:1354959 20130904 MGI:MGI PR:Q80VA5-1 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 (mouse) mSH3TC2/iso:1 located_in GO:0055037 recycling endosome MGI_ref:4366127|PMID:19805030 IDA NCBITaxon:10090 MGI:2444417 20120507 MGI:MGI PR:Q80W99 cation channel sperm-associated protein 3 (mouse) Catsper3|CatSper3 (mouse)|mCATSPER3 located_in GO:0001669 acrosomal vesicle PMID:16107607 IDA NCBITaxon:10090 UniProtKB:Q80W99 20080601 PRO:CNA PR:Q80W99 cation channel sperm-associated protein 3 (mouse) Catsper3|CatSper3 (mouse)|mCATSPER3 acts_upstream_of_or_within GO:0001539 cilium or flagellum-dependent cell motility PMID:17227845 IDA NCBITaxon:10090 UniProtKB:Q80W99 20080601 PRO:CNA PR:Q80W99 cation channel sperm-associated protein 3 (mouse) Catsper3|CatSper3 (mouse)|mCATSPER3 acts_upstream_of_or_within GO:0030317 flagellated sperm motility PMID:17227845 IDA NCBITaxon:10090 UniProtKB:Q80W99 20080601 PRO:CNA PR:Q80W99-1 cation channel sperm-associated protein 3 isoform 1 (mouse) mCATSPER3/iso:1 enables GO:0005515 protein binding PR:Q91ZR5-1 PMID:17227845 IPI NCBITaxon:10090 UniProtKB:Q80W99-1 20080601 PRO:CNA PR:Q80YE4-1 serine/threonine-protein kinase LMTK1 isoform 1 (mouse) mAATK/iso:1 acts_upstream_of_or_within GO:0046777 protein autophosphorylation MGI_ref:3766666|PMID:17651901 IDA NCBITaxon:10090 MGI:1197518 20101103 MGI:MGI PR:Q80YE4-2 serine/threonine-protein kinase LMTK1 isoform 2 (mouse) AATYK1A (mouse)|mAATK/iso:2 enables GO:0005515 protein binding PR:P12931 MGI_ref:3820458|PMID:18691334 IPI NCBITaxon:10090 MGI:1197518 20140214 MGI:MGI PR:Q80YE4-2 serine/threonine-protein kinase LMTK1 isoform 2 (mouse) AATYK1A (mouse)|mAATK/iso:2 acts_upstream_of_or_within GO:0046777 protein autophosphorylation MGI_ref:3766666|PMID:17651901 IDA NCBITaxon:10090 MGI:1197518 20111207 MGI:MGI PR:Q80YE4-3 serine/threonine-protein kinase LMTK1 isoform 3 (mouse) AATYK1B (mouse)|mAATK/iso:3 located_in GO:0005783 endoplasmic reticulum MGI_ref:3820458|PMID:18691334 IDA NCBITaxon:10090 MGI:1197518 20130118 MGI:MGI PR:Q80YE4-3 serine/threonine-protein kinase LMTK1 isoform 3 (mouse) AATYK1B (mouse)|mAATK/iso:3 acts_upstream_of_or_within GO:0046777 protein autophosphorylation MGI_ref:3766666|PMID:17651901 IDA NCBITaxon:10090 MGI:1197518 20111207 MGI:MGI PR:Q80YE7-1 death-associated protein kinase 1 isoform 1 (mouse) death-associated protein kinase 1 isoform Beta (mouse)|mDAPK1/iso:1 acts_upstream_of_or_within GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors MGI_ref:2152512|PMID:11485996 IDA NCBITaxon:10090 MGI:1916885 20130621 MGI:MGI PR:Q80YQ2-1 mediator of RNA polymerase II transcription subunit 23 isoform 1 (mouse) mMED23/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1917458 20120523 MGI:MGI PR:Q80ZV0 ribonuclease H2 subunit B (mouse) deleted in lymphocytic leukemia 8 homolog (mouse)|Dleu8|mRNASEH2B|ribonuclease HI subunit B (mouse)|RNase H2 subunit B (mouse)|Rnaseh2b part_of GO:0032299 ribonuclease H2 complex PMID:19923215 EXP NCBITaxon:10090 UniProtKB:Q80ZV0 20111003 PRO:HJD PR:Q810B3-1 brain-specific homeobox protein homolog isoform 1 (mouse) Bsx1a (mouse)|mBSX/iso:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI_ref:3713592|PMID:17353277 IDA NCBITaxon:10090 MGI:2669849 20080223 MGI:MGI PR:Q810B3-1 brain-specific homeobox protein homolog isoform 1 (mouse) Bsx1a (mouse)|mBSX/iso:1 enables GO:0043565 sequence-specific DNA binding MGI_ref:3713592|PMID:17353277 IDA NCBITaxon:10090 MGI:2669849 20080223 MGI:MGI PR:Q810B3-1 brain-specific homeobox protein homolog isoform 1 (mouse) Bsx1a (mouse)|mBSX/iso:1 located_in GO:0005634 nucleus MGI_ref:3713592|PMID:17353277 IDA NCBITaxon:10090 MGI:2669849 20080223 MGI:MGI PR:Q810B3-1 brain-specific homeobox protein homolog isoform 1 (mouse) Bsx1a (mouse)|mBSX/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3713592|PMID:17353277 IDA NCBITaxon:10090 MGI:2669849 20080223 MGI:MGI PR:Q810B3-2 brain-specific homeobox protein homolog isoform 2 (mouse) Bsx1b (mouse)|mBSX/iso:2 located_in GO:0005737 cytoplasm MGI_ref:3713592|PMID:17353277 IDA NCBITaxon:10090 MGI:2669849 20080223 MGI:MGI PR:Q8BG87-1 methylcytosine dioxygenase TET3 isoform 1 (mouse) mTET3/iso:1 enables GO:0070579 5-methylcytosine dioxygenase activity MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BG87-1 methylcytosine dioxygenase TET3 isoform 1 (mouse) mTET3/iso:1 located_in GO:0005634 nucleus MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BG87-1 methylcytosine dioxygenase TET3 isoform 1 (mouse) mTET3/iso:1 acts_upstream_of_or_within GO:0080111 DNA demethylation MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BG87-4 methylcytosine dioxygenase TET3 isoform 3 (mouse) mTET3/iso:3|Tet3CXXC (mouse) enables GO:0070579 5-methylcytosine dioxygenase activity MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BG87-4 methylcytosine dioxygenase TET3 isoform 3 (mouse) mTET3/iso:3|Tet3CXXC (mouse) located_in GO:0005634 nucleus MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BG87-4 methylcytosine dioxygenase TET3 isoform 3 (mouse) mTET3/iso:3|Tet3CXXC (mouse) acts_upstream_of_or_within GO:0080111 DNA demethylation MGI_ref:5525037|PMID:23690950 IDA NCBITaxon:10090 MGI:2446229 20150708 MGI:MGI PR:Q8BIF2-1 RNA binding protein fox-1 homolog 3 isoform 1 (mouse) Fox-3-L (mouse)|Fox3v1 (mouse)|mRBFOX3/iso:1 enables GO:0005515 protein binding PR:Q8VIJ6 MGI_ref:5050057|PMID:21177649 IPI NCBITaxon:10090 MGI:106368 20140613 MGI:MGI PR:Q8BIF2-1 RNA binding protein fox-1 homolog 3 isoform 1 (mouse) Fox-3-L (mouse)|Fox3v1 (mouse)|mRBFOX3/iso:1 located_in GO:0005634 nucleus MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120430 MGI:MGI PR:Q8BIF2-1 RNA binding protein fox-1 homolog 3 isoform 1 (mouse) Fox-3-L (mouse)|Fox3v1 (mouse)|mRBFOX3/iso:1 located_in GO:0005634 nucleus MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 UniProtKB:Q8BIF2-1 20120502 PRO:HJD PR:Q8BIF2-1 RNA binding protein fox-1 homolog 3 isoform 1 (mouse) Fox-3-L (mouse)|Fox3v1 (mouse)|mRBFOX3/iso:1 acts_upstream_of_or_within GO:0000381 regulation of alternative mRNA splicing, via spliceosome MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120430 MGI:MGI PR:Q8BIF2-1 RNA binding protein fox-1 homolog 3 isoform 1 (mouse) Fox-3-L (mouse)|Fox3v1 (mouse)|mRBFOX3/iso:1 acts_upstream_of_or_within GO:0000381 regulation of alternative mRNA splicing, via spliceosome MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 UniProtKB:Q8BIF2-1 20120502 PRO:HJD PR:Q8BIF2-4 RNA binding protein fox-1 homolog 3 isoform 4 (mouse) Fox3v3 (mouse)|mRBFOX3/iso:4 located_in GO:0005737 cytoplasm MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120430 MGI:MGI PR:Q8BIF2-4 RNA binding protein fox-1 homolog 3 isoform 4 (mouse) Fox3v3 (mouse)|mRBFOX3/iso:4 acts_upstream_of_or_within GO:0000381 regulation of alternative mRNA splicing, via spliceosome MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120501 MGI:MGI PR:Q8BIF2-5 RNA binding protein fox-1 homolog 3 isoform 5 (mouse) Fox-3-S (mouse)|Fox3v2 (mouse)|mRBFOX3/iso:5 enables GO:0005515 protein binding PR:Q8VIJ6 MGI_ref:5050057|PMID:21177649 IPI NCBITaxon:10090 MGI:106368 20140613 MGI:MGI PR:Q8BIF2-5 RNA binding protein fox-1 homolog 3 isoform 5 (mouse) Fox-3-S (mouse)|Fox3v2 (mouse)|mRBFOX3/iso:5 located_in GO:0005634 nucleus MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120430 MGI:MGI PR:Q8BIF2-5 RNA binding protein fox-1 homolog 3 isoform 5 (mouse) Fox-3-S (mouse)|Fox3v2 (mouse)|mRBFOX3/iso:5 acts_upstream_of_or_within GO:0000381 regulation of alternative mRNA splicing, via spliceosome MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120501 MGI:MGI PR:Q8BIF2-5 RNA binding protein fox-1 homolog 3 isoform 5 (mouse) Fox-3-S (mouse)|Fox3v2 (mouse)|mRBFOX3/iso:5 NOT located_in GO:0005737 cytoplasm MGI_ref:5140633|PMID:21747913 IDA NCBITaxon:10090 MGI:106368 20120430 MGI:MGI PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) enables GO:0005216 monoatomic ion channel activity PMID:15483558 IMP NCBITaxon:10090 UniProtKB:Q8BLA8 20080923 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:18398506 IMP NCBITaxon:10090 MGI_allele:3692770 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0009409 response to cold PMID:12654248|PMID:16630838 IMP NCBITaxon:10090 UniProtKB:Q8BLA8 20080701 PRO:CNA PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0009410 response to xenobiotic stimulus PMID:18272293 IDA NCBITaxon:10090 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0042542 response to hydrogen peroxide PMID:18398506 IMP NCBITaxon:10090 MGI_allele:3692770 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0048265 response to pain PMID:16630838 IMP NCBITaxon:10090 MGI_allele:3624810 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0048265 response to pain PMID:18297068 IMP NCBITaxon:10090 MGI_allele:3624810 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050955 thermoception PMID:12654248 IDA NCBITaxon:10090 UniProtKB:Q8BLA8 20080701 PRO:CNA PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050966 detection of mechanical stimulus involved in sensory perception of pain PMID:16630838 IMP NCBITaxon:10090 MGI_allele:3624810 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050968 detection of chemical stimulus involved in sensory perception of pain PMID:16564016 IMP NCBITaxon:10090 MGI_allele:3692770 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050968 detection of chemical stimulus involved in sensory perception of pain PMID:16630838 IMP NCBITaxon:10090 MGI_allele:3624810 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050968 detection of chemical stimulus involved in sensory perception of pain PMID:18272293 IDA NCBITaxon:10090 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050968 detection of chemical stimulus involved in sensory perception of pain PMID:18297068 IMP NCBITaxon:10090 MGI_allele:3624810 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8 transient receptor potential cation channel subfamily A member 1 (mouse) Anktm1|ankyrin-like with transmembrane domains protein 1 (mouse)|mTRPA1|Trpa1|wasabi receptor (mouse) acts_upstream_of_or_within GO:0050968 detection of chemical stimulus involved in sensory perception of pain PMID:18398506 IMP NCBITaxon:10090 MGI_allele:3692770 UniProtKB:Q8BLA8 20080929 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 enables GO:0015267 channel activity PMID:15483558 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080923 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 located_in GO:0032421 stereocilium bundle PMID:15483558 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080923 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:17588549 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080923 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 acts_upstream_of_or_within GO:0009409 response to cold PMID:12654248 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20051209 mgi:LN PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 acts_upstream_of_or_within GO:0048265 response to pain PMID:18272293 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080923 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 acts_upstream_of_or_within GO:0050955 thermoception PMID:12654248 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20051209 mgi:LN PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 contributes_to enables GO:0005262 calcium channel activity PMID:12654248 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20051209 mgi:LN PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 contributes_to enables GO:0005262 calcium channel activity PMID:17588549 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080923 mgi:HJD PR:Q8BLA8-1 transient receptor potential cation channel subfamily A member 1 isoform 1 (mouse) mTRPA1/iso:1 contributes_to enables GO:0005262 calcium channel activity PMID:18398506 IDA NCBITaxon:10090 UniProtKB:Q8BLA8-1 20080924 mgi:HJD PR:Q8BUN5-1 mothers against decapentaplegic homolog 3 isoform 1 (mouse) mSMAD3/iso:1 enables GO:0005515 protein binding PR:000036434 PMID:12154125 IPI NCBITaxon:10090 UniProtKB:Q8BUN5-1 20100930 PRO:CNA PR:Q8BUN5-1 mothers against decapentaplegic homolog 3 isoform 1 (mouse) mSMAD3/iso:1 enables GO:0005515 protein binding PR:A2A8R0 PMID:12154125 IPI NCBITaxon:10090 UniProtKB:Q8BUN5-1 20100930 PRO:CNA PR:Q8BUN5-1 mothers against decapentaplegic homolog 3 isoform 1 (mouse) mSMAD3/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12543979 IDA NCBITaxon:10090 UniProtKB:Q8BUN5-1 20080301 PRO:CNA PR:Q8BVM7-1 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 1 (mouse) ALS2CR12-L (mouse)|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog|mALS2CR12/iso:1 located_in GO:0001520 outer dense fiber MGI_ref:4950293|PMID:21402173 IDA NCBITaxon:10090 MGI:1918359 20130313 MGI:MGI part_of(CL:0000019) PR:Q8BVM7-1 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 1 (mouse) ALS2CR12-L (mouse)|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog|mALS2CR12/iso:1 located_in GO:0005737 cytoplasm MGI_ref:4950293|PMID:21402173 IDA NCBITaxon:10090 MGI:1918359 20130314 MGI:MGI PR:Q8BVM7-1 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 1 (mouse) ALS2CR12-L (mouse)|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog|mALS2CR12/iso:1 located_in GO:0035686 sperm fibrous sheath MGI_ref:4950293|PMID:21402173 IDA NCBITaxon:10090 MGI:1918359 20130313 MGI:MGI part_of(CL:0000019) PR:Q8BVM7-1 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 1 (mouse) ALS2CR12-L (mouse)|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein homolog|mALS2CR12/iso:1 located_in GO:0036126 sperm flagellum MGI_ref:4950293|PMID:21402173 IDA NCBITaxon:10090 MGI:1918359 20130313 MGI:MGI part_of(CL:0000019) PR:Q8BVM7-2 amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform 2 (mouse) ALS2CR12-S (mouse)|mALS2CR12/iso:2 located_in GO:0005737 cytoplasm MGI_ref:4950293|PMID:21402173 IDA NCBITaxon:10090 MGI:1918359 20130313 MGI:MGI PR:Q8C208-1 zinc finger protein Eos isoform 1 (mouse) mIKZF4/iso:1 enables GO:0046982 protein heterodimerization activity PR:Q03267-1 PMID:10218586 IPI NCBITaxon:10090 UniProtKB:Q8C208-1 20090515 MGI:MGI PR:Q8C208-2 zinc finger protein Eos isoform 2 (mouse) mIKZF4/iso:2 enables GO:0042803 protein homodimerization activity PR:Q8C208-1 PMID:10218586 IPI NCBITaxon:10090 UniProtKB:Q8C208-2 20090515 MGI:MGI PR:Q8C460-1 ERI1 exoribonuclease 3 isoform 1 (mouse) mERI3/iso:1 enables GO:0005515 protein binding PR:P04925 MGI_ref:2153789|PMID:11571277 IPI NCBITaxon:10090 MGI:2153887 20100420 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 enables GO:0003677 DNA binding MGI_ref:894957|PMID:9256341 IDA NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 enables GO:0005515 protein binding PR:P08152-2 MGI_ref:3629292|PMID:16675951 IPI NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 enables GO:0005515 protein binding PR:P29037 PMID:16522640 IPI NCBITaxon:10090 UniProtKB:Q8C5D8-1 20091109 PRO:HJD PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 enables GO:0019789 SUMO transferase activity PMID:15767674 EXP NCBITaxon:10090 UniProtKB:Q8C5D8-1 20091109 PRO:HJD PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 located_in GO:0005634 nucleus PMID:16522640 EXP NCBITaxon:10090 UniProtKB:Q8C5D8-1 20091109 PRO:HJD PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 located_in GO:0016604 nuclear body MGI_ref:3629292|PMID:16675951 IDA NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 acts_upstream_of_or_within GO:0006351 DNA-templated transcription MGI_ref:894957|PMID:9256341 IDA NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 acts_upstream_of_or_within GO:0006357 regulation of transcription by RNA polymerase II MGI_ref:894957|PMID:9256341 IDA NCBITaxon:10090 MGI:1096566 20110610 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 acts_upstream_of_or_within GO:0016925 protein sumoylation PMID:15767674 EXP NCBITaxon:10090 UniProtKB:Q8C5D8-1 20091109 PRO:HJD PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 acts_upstream_of_or_within GO:0045667 regulation of osteoblast differentiation MGI_ref:3723333|PMID:17623776 IMP NCBITaxon:10090 MGI:1096566 20091109 MGI:MGI PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse) E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)|mPIAS2/iso:1 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription MGI_ref:3723333|PMID:17623776 IDA NCBITaxon:10090 MGI:1096566 20110614 MGI:MGI PR:Q8C5D8-2 E3 SUMO-protein ligase PIAS2 isoform 2 (mouse) E3 SUMO-protein ligase PIAS2 isoform ARIP3 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-alpha (mouse)|mPIAS2/iso:2 enables GO:0005515 protein binding PR:P98078-3 MGI_ref:1929027|PMID:11104669 IPI NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8C5D8-2 E3 SUMO-protein ligase PIAS2 isoform 2 (mouse) E3 SUMO-protein ligase PIAS2 isoform ARIP3 (mouse)|E3 SUMO-protein ligase PIAS2 isoform PIASx-alpha (mouse)|mPIAS2/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1929027|PMID:11104669 IDA NCBITaxon:10090 MGI:1096566 20091104 MGI:MGI PR:Q8CG82 selection and upkeep of intraepithelial T-cells protein 2 isoform 5 (mouse) B7S3S (mouse)|mSkint2/iso:5 located_in GO:0005886 plasma membrane MGI_ref:3830586|PMID:17339463 IDA NCBITaxon:10090 MGI:3649629 20150529 MGI:MGI PR:Q8CGN4-1 BCL-6 corepressor isoform 1 (mouse) BCL-6 corepressor isoform A (mouse)|mBCOR/iso:1 enables GO:0005515 protein binding PR:A2AM29 MGI_ref:2682643|PMID:12776190 IPI NCBITaxon:10090 MGI:1918708 20081103 MGI:MGI PR:Q8CGN4-2 BCL-6 corepressor isoform 2 (mouse) BCL-6 corepressor isoform B (mouse)|mBCOR/iso:2 enables GO:0005515 protein binding PR:A2AM29 MGI_ref:2682643|PMID:12776190 IPI NCBITaxon:10090 MGI:1918708 20111207 MGI:MGI PR:Q8CHV6-1 transcriptional adapter 2-alpha isoform 1 (mouse) mTADA2A/iso:1|Tada2l isoform 1 (mouse) part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:2144471 20120611 MGI:MGI PR:Q8CIG3 lysine-specific histone demethylase 1B (mouse) Aof1|flavin-containing amine oxidase domain-containing protein 1 (mouse)|Kdm1b|Lsd2|lysine-specific histone demethylase 2 (mouse)|mKDM1B acts_upstream_of_or_within GO:0071514 genomic imprinting PMID:19727073 IMP NCBITaxon:10090 MGI_allele:4359289 UniProtKB:Q8CIG3 20091013 PRO:HJD PR:Q8CIG3-1 lysine-specific histone demethylase 1B isoform 1 (mouse) mKDM1B/iso:1 enables GO:0008270 zinc ion binding PMID:19407342 EXP NCBITaxon:10090 UniProtKB:Q8CIG3-1 20091013 PRO:HJD PR:Q8CIG3-1 lysine-specific histone demethylase 1B isoform 1 (mouse) mKDM1B/iso:1 enables GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity PMID:19407342 EXP NCBITaxon:10090 UniProtKB:Q8CIG3-1 20091013 PRO:HJD PR:Q8CIG3-1 lysine-specific histone demethylase 1B isoform 1 (mouse) mKDM1B/iso:1 enables GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity PMID:19727073 EXP NCBITaxon:10090 UniProtKB:Q8CIG3-1 20091013 PRO:HJD PR:Q8CIG3-1 lysine-specific histone demethylase 1B isoform 1 (mouse) mKDM1B/iso:1 enables GO:0050660 flavin adenine dinucleotide binding PMID:19407342 EXP NCBITaxon:10090 UniProtKB:Q8CIG3-1 20091013 PRO:HJD PR:Q8CIG3-1 lysine-specific histone demethylase 1B isoform 1 (mouse) mKDM1B/iso:1 located_in GO:0005634 nucleus PMID:19727073 EXP NCBITaxon:10090 UniProtKB:Q8CIG3-1 20091013 PRO:HJD PR:Q8CIV7-1 transcription factor Ovo-like 2 isoform 1 (mouse) MOVO-A|mOVOL2/iso:1 acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription MGI_ref:3051084|PMID:15225875 IDA NCBITaxon:10090 MGI:1338039 20080807 MGI:MGI PR:Q8CIV7-2 transcription factor Ovo-like 2 isoform 2 (mouse) MOVO-C|mOVOL2/iso:2 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription MGI_ref:3051084|PMID:15225875 IDA NCBITaxon:10090 MGI:1338039 20080813 MGI:MGI PR:Q8CIZ9-2 NADPH oxidase 1 isoform 2 (mouse) mNOX1/iso:2|NADPH oxidase 1 a-type (mouse)|NADPH oxidase 1 alpha (mouse) enables GO:0106292 superoxide-generating NADPH oxidase activity MGI_ref:2449827|PMID:12473664 IDA NCBITaxon:10090 MGI:2450016 20100602 MGI:MGI PR:Q8CIZ9-2 NADPH oxidase 1 isoform 2 (mouse) mNOX1/iso:2|NADPH oxidase 1 a-type (mouse)|NADPH oxidase 1 alpha (mouse) acts_upstream_of_or_within GO:0042554 superoxide anion generation MGI_ref:2449827|PMID:12473664 IDA NCBITaxon:10090 MGI:2450016 20100602 MGI:MGI PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0004672 protein kinase activity PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0005515 protein binding PR:O42263 PMID:17709426 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0005515 protein binding PR:P70039 PMID:17709426 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0005515 protein binding PR:P79935 PMID:12163471 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q6DFD4. Target=PR:P79935. Kinase activity not required for interaction. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0005515 protein binding PR:Q6DFD4 PMID:12163471 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Kinase activity not required for interaction. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 enables GO:0005515 protein binding PR:Q9YGY3 PMID:12163471 IPI NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Kinase activity not required for interaction. Timing=throughout cell cycle and upon spindle disruption (nocodazole). PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 located_in GO:0000776 kinetochore PMID:12163471|PMID:17709426 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Timing=Mitosis and spindle disruption (nocodazole). Kinetochore localization requires Bub1 and is increased by Mad1. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 located_in GO:0005694 chromosome PMID:15241477|PMID:16950116 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Timing=spindle disruption (nocodazole). PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q6DFD4. Target=PR:Q9YGY3. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q6GPD1. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:O42263. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:P79935. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q6GPD1. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q98UH3. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:Q9YGY3. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17709426 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER Target=PR:P70039. PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) frog-BUB1B|xBUBR1 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:17709426 EXP NCBITaxon:8355 UniProtKB:Q8JGT8 20130102 PRO:KER PR:Q8K078-1 solute carrier organic anion transporter family member 4A1 isoform 1 (mouse) mSLCO4A1/iso:1 enables GO:0008514 organic anion transmembrane transporter activity MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031051|UniProtKB:Q96BD0-1 MGI:1351866 20090326 MGI:MGI PR:Q8K078-1 solute carrier organic anion transporter family member 4A1 isoform 1 (mouse) mSLCO4A1/iso:1 located_in GO:0005886 plasma membrane MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031051|UniProtKB:Q96BD0-1 MGI:1351866 20090326 MGI:MGI PR:Q8K078-1 solute carrier organic anion transporter family member 4A1 isoform 1 (mouse) mSLCO4A1/iso:1 acts_upstream_of_or_within GO:0015711 organic anion transport MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031051|UniProtKB:Q96BD0-1 MGI:1351866 20090326 MGI:MGI PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse) mLMBRD1/iso:1 acts_upstream_of_or_within GO:0038016 insulin receptor internalization MGI_ref:5543853|PMID:24078630 IMP NCBITaxon:10090 MGI_allele:5559223 MGI:1915671 20140422 MGI:MGI PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse) mLMBRD1/iso:1 acts_upstream_of_or_within GO:0046325 negative regulation of glucose import MGI_ref:5543853|PMID:24078630 IMP NCBITaxon:10090 MGI_allele:5559223 MGI:1915671 20140422 MGI:MGI occurs_in(CL:0000746) PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse) mLMBRD1/iso:1 acts_upstream_of_or_within GO:0046627 negative regulation of insulin receptor signaling pathway MGI_ref:5543853|PMID:24078630 IMP NCBITaxon:10090 MGI_allele:5559223 MGI:1915671 20140422 MGI:MGI occurs_in(CL:0000746) PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse) mLMBRD1/iso:1 acts_upstream_of_or_within GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5543853|PMID:24078630 IMP NCBITaxon:10090 MGI_allele:5559223 MGI:1915671 20140422 MGI:MGI PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse) mLMBRD1/iso:1 NOT acts_upstream_of_or_within GO:0043408 regulation of MAPK cascade MGI_ref:5543853|PMID:24078630 IMP NCBITaxon:10090 MGI_allele:5559223 MGI:1915671 20140422 MGI:MGI PR:Q8K0L0-1 ankyrin repeat and SOCS box protein 2 isoform 1 (mouse) ASB2beta (mouse)|mASB2/iso:1 part_of GO:0031466 Cul5-RING ubiquitin ligase complex MGI_ref:4830849|PMID:19300455 IDA NCBITaxon:10090 MGI:1929743 20130111 MGI:MGI has_direct_input(MGI:2446089) PR:Q8K0L0-1 ankyrin repeat and SOCS box protein 2 isoform 1 (mouse) ASB2beta (mouse)|mASB2/iso:1 acts_upstream_of_or_within GO:0000209 protein polyubiquitination MGI_ref:4830849|PMID:19300455 IDA NCBITaxon:10090 MGI:1929743 20130111 MGI:MGI has_input(MGI:MGI:2446089) PR:Q8K0L0-1 ankyrin repeat and SOCS box protein 2 isoform 1 (mouse) ASB2beta (mouse)|mASB2/iso:1 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process MGI_ref:4830849|PMID:19300455 IDA NCBITaxon:10090 MGI:1929743 20130111 MGI:MGI has_direct_input(MGI:MGI:2446089) PR:Q8K0L0-1 ankyrin repeat and SOCS box protein 2 isoform 1 (mouse) ASB2beta (mouse)|mASB2/iso:1 acts_upstream_of_or_within GO:0045445 myoblast differentiation MGI_ref:4830849|PMID:19300455 IMP NCBITaxon:10090 MGI:1929743 20130111 MGI:MGI PR:Q8K0L0-1 ankyrin repeat and SOCS box protein 2 isoform 1 (mouse) ASB2beta (mouse)|mASB2/iso:1 contributes_to enables GO:0061630 ubiquitin protein ligase activity MGI_ref:4830849|PMID:19300455 IDA NCBITaxon:10090 MGI:1929743 20141025 MGI:MGI PR:Q8K302 zinc finger CCCH-type antiviral protein 1 isoform 4 (mouse) mZC3HAV1/iso:4|PARP-13.2 (mouse)|zinc finger CCCH-type antiviral protein 1 isoform ZAPS (mouse) located_in GO:0005634 nucleus MGI_ref:5499037|PMID:23776219 IDA NCBITaxon:10090 MGI:1926031 20140904 MGI:MGI PR:Q8K302 zinc finger CCCH-type antiviral protein 1 isoform 4 (mouse) mZC3HAV1/iso:4|PARP-13.2 (mouse)|zinc finger CCCH-type antiviral protein 1 isoform ZAPS (mouse) located_in GO:0005737 cytoplasm MGI_ref:5499037|PMID:23776219 IDA NCBITaxon:10090 MGI:1926031 20140904 MGI:MGI PR:Q8K424-1 transient receptor potential cation channel subfamily V member 3 isoform A (mouse) mTRPV3/iso:A|transient receptor potential cation channel subfamily V member 3 isoform 1 (mouse)|Trpv3 isoform 1 (mouse) acts_upstream_of_or_within GO:0009266 response to temperature stimulus PMID:12016205 IDA NCBITaxon:10090 UniProtKB:Q8K424-1 20080923 mgi:HJD PR:Q8K424-1 transient receptor potential cation channel subfamily V member 3 isoform A (mouse) mTRPV3/iso:A|transient receptor potential cation channel subfamily V member 3 isoform 1 (mouse)|Trpv3 isoform 1 (mouse) contributes_to enables GO:0005261 monoatomic cation channel activity PMID:12016205 IDA NCBITaxon:10090 UniProtKB:Q8K424-1 20080923 mgi:HJD PR:Q8K450-1 sperm-associated antigen 16 protein isoform 1 (mouse) mSPAG16/iso:1|sperm-associated antigen 16 protein isoform SPAG16L (mouse) located_in GO:1990716 axonemal central apparatus MGI_ref:3766863|PMID:17699735 IMP NCBITaxon:10090 MGI_allele:3606979 MGI:1913972 20150413 MGI:MGI part_of(CL:0000019) PR:Q8K4B2 interleukin-1 receptor-associated kinase 3 (mouse) IL-1 receptor-associated kinase M (mouse)|inactive IL-1 receptor-associated kinase 3 (mouse)|IRAK-3 (mouse)|IRAK-M (mouse)|Irak3|mIRAK3 acts_upstream_of_or_within GO:0034122 negative regulation of toll-like receptor signaling pathway PMID:12150927 IMP NCBITaxon:10090 MGI_allele:2384197 UniProtKB:Q8K4B2 20110620 PRO:CNA PR:Q8K4C2-1 interleukin-17 receptor C isoform 1 (mouse) mIL17RC/iso:1 enables GO:0005515 protein binding PR:Q7TNI7 MGI_ref:4360610|PMID:17911633 IPI NCBITaxon:10090 MGI:2159336 20120424 MGI:MGI PR:Q8K4K6-1 pantothenate kinase 1 isoform 1 (mouse) mPANK1/iso:1|PanK1-alpha (mouse) enables GO:0004594 pantothenate kinase activity MGI_ref:2182912|PMID:12095677 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-1 pantothenate kinase 1 isoform 1 (mouse) mPANK1/iso:1|PanK1-alpha (mouse) located_in GO:0005634 nucleus MGI_ref:5484508|PMID:23152917 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) enables GO:0004594 pantothenate kinase activity MGI_ref:2182912|PMID:12095677 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) enables GO:0004594 pantothenate kinase activity MGI_ref:3607004|PMID:16040613 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) located_in GO:0005829 cytosol MGI_ref:5484508|PMID:23152917 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) part_of GO:0030118 clathrin coat MGI_ref:5484508|PMID:23152917 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) located_in GO:0055037 recycling endosome MGI_ref:5484508|PMID:23152917 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4K6-2 pantothenate kinase 1 isoform 2 (mouse) mPANK1/iso:2|PanK1-beta (mouse) acts_upstream_of_or_within GO:0015937 coenzyme A biosynthetic process MGI_ref:3607004|PMID:16040613 IDA NCBITaxon:10090 MGI:1922985 20130807 MGI:MGI PR:Q8K4T3-1 STE20-related kinase adapter protein beta isoform 1 (mouse) mSTRADB/iso:1|PAPK-A (mouse) enables GO:0004672 protein kinase activity MGI_ref:2656105|PMID:12574163 IDA NCBITaxon:10090 MGI:2144047 20110106 MGI:MGI PR:Q8K4Z3-1 NAD(P)H-hydrate epimerase isoform 1 (mouse) mNAXE/iso:1 located_in GO:0005739 mitochondrion MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:2180167 20150603 MGI:MGI PR:Q8K592-1 anti-Muellerian hormone type-2 receptor isoform 1 (mouse) mAMHR2/iso:1 enables GO:1990272 anti-Mullerian hormone receptor activity MGI_ref:5499265|PMID:23624077 IDA NCBITaxon:10090 MGI:105062 20140117 MGI:MGI has_direct_input(UniProtKB:Q5EC55) PR:Q8K592-1 anti-Muellerian hormone type-2 receptor isoform 1 (mouse) mAMHR2/iso:1 acts_upstream_of_or_within GO:0007548 sex differentiation PMID:8895659 IDA NCBITaxon:10090 UniProtKB:Q8K592-1 20080301 PRO:CNA PR:Q8K592-1 anti-Muellerian hormone type-2 receptor isoform 1 (mouse) mAMHR2/iso:1 acts_upstream_of_or_within GO:1990262 anti-Mullerian hormone receptor signaling pathway MGI_ref:5499265|PMID:23624077 IDA NCBITaxon:10090 MGI:105062 20140114 MGI:MGI PR:Q8N2H9-2 E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human) hPELI3/iso:2|pellino 3 beta (human)|pellino 3b (human)|pellino-3 beta (human) acts_upstream_of_or_within GO:0070534 protein K63-linked ubiquitination PMID:18326498 IDA NCBITaxon:9606 UniProtKB:Q8N2H9-2 20110503 PRO:CNA Note=on IRAK, complex with Ubc13/Uev1A PR:Q8N2H9-2 E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human) hPELI3/iso:2|pellino 3 beta (human)|pellino 3b (human)|pellino-3 beta (human) acts_upstream_of_or_within GO:2000660 negative regulation of interleukin-1-mediated signaling pathway PMID:18326498 IDA NCBITaxon:9606 UniProtKB:Q8N2H9-2 20110503 PRO:CNA PR:Q8NCM2 potassium voltage-gated channel subfamily H member 5 (human) EAG2|ether-a-go-go potassium channel 2 (human)|hEAG2|hKCNH5|KCNH5|voltage-gated potassium channel subunit Kv10.2 (human) part_of GO:0008076 voltage-gated potassium channel complex PMID:11943152|PMID:9738473 IDA NCBITaxon:9606 PR:000002664 UniProtKB:Q8NCM2 20080601 PRO:CNA PR:Q8NEC5-1 cation channel sperm-associated protein 1 isoform 1 (human) hCATSPER1/iso:1 enables GO:0005515 protein binding PR:Q9P0X4 PMID:16740636 IPI NCBITaxon:9606 UniProtKB:Q8NEC5-1 20080601 PRO:CNA PR:Q8NER5-4 activin receptor type-1C isoform 4 (human) activin receptor type-1C isoform Truncated (human)|hACVR1C/iso:4 located_in GO:0005886 plasma membrane PMID:12606401 IDA NCBITaxon:9606 UniProtKB:Q8NER5-4 20080301 PRO:CNA PR:Q8NET8-1 transient receptor potential cation channel subfamily V member 3 isoform 1 (human) hTRPV3/iso:1 acts_upstream_of_or_within GO:0009266 response to temperature stimulus PMID:12077604|PMID:12077606 IDA NCBITaxon:9606 UniProtKB:Q8NET8-1 20080923 mgi:HJD PR:Q8NET8-1 transient receptor potential cation channel subfamily V member 3 isoform 1 (human) hTRPV3/iso:1 contributes_to enables GO:0005261 monoatomic cation channel activity PMID:12077604|PMID:12077606 IDA NCBITaxon:9606 UniProtKB:Q8NET8-1 20080923 mgi:HJD PR:Q8NG31 kinetochore scaffold 1 (human) AF15q14 (human)|ALL1-fused gene from chromosome 15q14 protein (human)|blinkin (human)|Bub-linking kinetochore protein (human)|cancer susceptibility candidate gene 5 protein (human)|cancer/testis antigen 29 (human)|CASC5|CT29 (human)|hKNL1|KIAA1570|kinetochore-null protein 1 (human)|KNL1|protein CASC5 (human)|protein D40/AF15q14 (human) enables GO:0005515 protein binding PR:O14777 BioGRID:BG-723196 IPI NCBITaxon:9606 UniProtKB:Q8NG31 20130103 PRO:KER PR:Q8NG31 kinetochore scaffold 1 (human) AF15q14 (human)|ALL1-fused gene from chromosome 15q14 protein (human)|blinkin (human)|Bub-linking kinetochore protein (human)|cancer susceptibility candidate gene 5 protein (human)|cancer/testis antigen 29 (human)|CASC5|CT29 (human)|hKNL1|KIAA1570|kinetochore-null protein 1 (human)|KNL1|protein CASC5 (human)|protein D40/AF15q14 (human) enables GO:0005515 protein binding PR:O43683 BioGRID:BG-723200 IPI NCBITaxon:9606 UniProtKB:Q8NG31 20130103 PRO:KER PR:Q8NG31 kinetochore scaffold 1 (human) AF15q14 (human)|ALL1-fused gene from chromosome 15q14 protein (human)|blinkin (human)|Bub-linking kinetochore protein (human)|cancer susceptibility candidate gene 5 protein (human)|cancer/testis antigen 29 (human)|CASC5|CT29 (human)|hKNL1|KIAA1570|kinetochore-null protein 1 (human)|KNL1|protein CASC5 (human)|protein D40/AF15q14 (human) enables GO:0005515 protein binding PR:O60566 BioGRID:BG-697221 IPI NCBITaxon:9606 UniProtKB:Q8NG31 20130103 PRO:KER PR:Q8NG31 kinetochore scaffold 1 (human) AF15q14 (human)|ALL1-fused gene from chromosome 15q14 protein (human)|blinkin (human)|Bub-linking kinetochore protein (human)|cancer susceptibility candidate gene 5 protein (human)|cancer/testis antigen 29 (human)|CASC5|CT29 (human)|hKNL1|KIAA1570|kinetochore-null protein 1 (human)|KNL1|protein CASC5 (human)|protein D40/AF15q14 (human) located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q8NG31 20121121 PRO:KER PR:Q8R037 tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse) mTNFRSF9/iso:2|sCD137 (mouse)|Secreted CD137 antigen (mouse) located_in GO:0005615 extracellular space MGI_ref:3807131|PMID:18640726 IDA NCBITaxon:10090 MGI:1101059 20121217 MGI:MGI part_of(CL:0000624)|part_of(CL:0000625) PR:Q8R037 tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse) mTNFRSF9/iso:2|sCD137 (mouse)|Secreted CD137 antigen (mouse) acts_upstream_of_or_within GO:0070207 protein homotrimerization MGI_ref:3807131|PMID:18640726 IDA NCBITaxon:10090 MGI:1101059 20121217 MGI:MGI PR:Q8R037 tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse) mTNFRSF9/iso:2|sCD137 (mouse)|Secreted CD137 antigen (mouse) acts_upstream_of_or_within GO:0032693 negative regulation of interleukin-10 production MGI_ref:3807131|PMID:18640726 IMP NCBITaxon:10090 MGI:1101059 20121217 MGI:MGI PR:Q8R037 tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse) mTNFRSF9/iso:2|sCD137 (mouse)|Secreted CD137 antigen (mouse) acts_upstream_of_or_within GO:0032695 negative regulation of interleukin-12 production MGI_ref:3807131|PMID:18640726 IMP NCBITaxon:10090 MGI:1101059 20121217 MGI:MGI PR:Q8R0L9-1 transcriptional adapter 3 isoform 1 (mouse) mTADA3/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1915724 20120611 MGI:MGI PR:Q8R104-1 NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse) mSIRT3/iso:1|Sirt3 Isoform L (mouse)|Sirt3 Isoform M1 (mouse) enables GO:0032041 NAD-dependent histone H3K14 deacetylase activity MGI_ref:4830236|PMID:19241369 IDA NCBITaxon:10090 MGI:1927665 20130111 MGI:MGI PR:Q8R104-1 NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse) mSIRT3/iso:1|Sirt3 Isoform L (mouse)|Sirt3 Isoform M1 (mouse) located_in GO:0005739 mitochondrion MGI_ref:4830236|PMID:19241369 IDA NCBITaxon:10090 MGI:1927665 20130111 MGI:MGI PR:Q8R104-1 NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse) mSIRT3/iso:1|Sirt3 Isoform L (mouse)|Sirt3 Isoform M1 (mouse) acts_upstream_of_or_within GO:0006476 protein deacetylation MGI_ref:4830236|PMID:19241369 IDA NCBITaxon:10090 MGI:1927665 20130111 MGI:MGI PR:Q8R104-2 NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse) mSIRT3/iso:2|Sirt3 Isoform M3 (mouse)|Sirt3 Isoform S (mouse) located_in GO:0005737 cytoplasm MGI_ref:1926994|PMID:11056054 IDA NCBITaxon:10090 MGI:1927665 20010103 MGI:MGI PR:Q8R104-2 NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse) mSIRT3/iso:2|Sirt3 Isoform M3 (mouse)|Sirt3 Isoform S (mouse) NOT enables GO:0032041 NAD-dependent histone H3K14 deacetylase activity MGI_ref:1926994|PMID:11056054 IDA NCBITaxon:10090 MGI:1927665 20130111 MGI:MGI PR:Q8R2F2 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse) degenerative spermatocyte homolog 2 (mouse)|Degs2|mDEGS2|sphingolipid 4-desaturase (mouse)|sphingolipid C4-monooxygenase (mouse) enables GO:0042284 sphingolipid delta-4 desaturase activity PMID:11937514 IGI NCBITaxon:10090 SGD:S000002705 UniProtKB:Q8R2F2 20100215 PRO:HJD PR:Q8R2F2 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse) degenerative spermatocyte homolog 2 (mouse)|Degs2|mDEGS2|sphingolipid 4-desaturase (mouse)|sphingolipid C4-monooxygenase (mouse) acts_upstream_of_or_within GO:0006667 sphinganine metabolic process PMID:11937514 IGI NCBITaxon:10090 SGD:S000002705 UniProtKB:Q8R2F2 20100215 PRO:HJD PR:Q8R2F2 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse) degenerative spermatocyte homolog 2 (mouse)|Degs2|mDEGS2|sphingolipid 4-desaturase (mouse)|sphingolipid C4-monooxygenase (mouse) acts_upstream_of_or_within GO:0030148 sphingolipid biosynthetic process PMID:11937514 IGI NCBITaxon:10090 SGD:S000002705 UniProtKB:Q8R2F2 20100215 PRO:HJD PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse) mDEGS2/iso:1 enables GO:0000170 sphingosine hydroxylase activity MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 UniProtKB:Q8R2F2-1 20100215 PRO:HJD PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse) mDEGS2/iso:1 enables GO:0000170 sphingosine hydroxylase activity MGI_ref:3056825|PMID:15474011 IDA NCBITaxon:10090 UniProtKB:Q8R2F2-1 20100215 PRO:HJD PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse) mDEGS2/iso:1 acts_upstream_of_or_within GO:0006667 sphinganine metabolic process MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 UniProtKB:Q8R2F2-1 20100215 PRO:HJD PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse) mDEGS2/iso:1 acts_upstream_of_or_within GO:0046513 ceramide biosynthetic process MGI_ref:3694278|PMID:16571104 IDA NCBITaxon:10090 UniProtKB:Q8R2F2-1 20100215 PRO:HJD PR:Q8R3B1-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1 (mouse) mPLCD1/iso:1 enables GO:0004629 phospholipase C activity MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:Q8R3B1-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1 (mouse) mPLCD1/iso:1 enables GO:0070300 phosphatidic acid binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:Q8R3B1-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1 (mouse) mPLCD1/iso:1 enables GO:1901981 phosphatidylinositol phosphate binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:Q8R3B1-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1 (mouse) mPLCD1/iso:1 NOT enables GO:0001786 phosphatidylserine binding MGI_ref:5520128|PMID:23892088 IDA NCBITaxon:10090 MGI:97614 20140527 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 enables GO:0008514 organic anion transmembrane transporter activity MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 enables GO:0035673 oligopeptide transmembrane transporter activity MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 located_in GO:0005886 plasma membrane MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 located_in GO:0009925 basal plasma membrane MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 located_in GO:0009986 cell surface MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 acts_upstream_of_or_within GO:0006857 oligopeptide transport MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-1 solute carrier organic anion transporter family member 3A1 isoform 1 (mouse) mSLCO3A1/iso:1 acts_upstream_of_or_within GO:0015711 organic anion transport MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:AB031050|EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R3L5-2 solute carrier organic anion transporter family member 3A1 isoform 2 (mouse) mSLCO3A1/iso:2 located_in GO:0016324 apical plasma membrane MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 EMBL:BC000585 MGI:1351867 20080327 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 enables GO:0015385 sodium:proton antiporter activity MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20080312 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 enables GO:0015386 potassium:proton antiporter activity MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20080312 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 located_in GO:0005794 Golgi apparatus MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20080312 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 acts_upstream_of_or_within GO:0006813 potassium ion transport MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20080312 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 acts_upstream_of_or_within GO:0006814 sodium ion transport MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20080312 MGI:MGI PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse) mSLC9A8/iso:1 acts_upstream_of_or_within GO:0051453 regulation of intracellular pH MGI_ref:3529663|PMID:15522866 IDA NCBITaxon:10090 MGI:1924281 20140926 MGI:MGI PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 enables GO:0005262 calcium channel activity PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 enables GO:0005262 calcium channel activity PMID:17538622 IMP NCBITaxon:10090 MGI_allele:3716518 UniProtKB:Q8R4D5 20081211 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 enables GO:0042803 protein homodimerization activity PR:Q8R4D5 PMID:17015441 IPI NCBITaxon:10090 UniProtKB:Q8R4D5 20081229 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 located_in GO:0009897 external side of plasma membrane PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0009409 response to cold PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0009409 response to cold PMID:17481391 IMP NCBITaxon:10090 MGI_allele:3716558 UniProtKB:Q8R4D5 20081211 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0009409 response to cold PMID:17481392 IMP NCBITaxon:10090 MGI_allele:3716553 UniProtKB:Q8R4D5 20081211 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0009409 response to cold PMID:17538622 IMP NCBITaxon:10090 MGI_allele:3716518 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0050955 thermoception PMID:17481391 IMP NCBITaxon:10090 MGI_allele:3716558 UniProtKB:Q8R4D5 20081211 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0050955 thermoception PMID:17481392 IMP NCBITaxon:10090 MGI_allele:3716553 UniProtKB:Q8R4D5 20081211 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0050955 thermoception PMID:17538622 IMP NCBITaxon:10090 MGI_allele:3716518 UniProtKB:Q8R4D5 20081210 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0051289 protein homotetramerization PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081215 mgi:HJD PR:Q8R4D5 transient receptor potential cation channel subfamily M member 8 (mouse) long transient receptor potential channel 6 (mouse)|LTrpC-6 (mouse)|Ltrpc6|LTrpC6 (mouse)|mTRPM8|transient receptor potential p8 (mouse)|Trp-p8 (mouse)|Trpm8|Trpp8 acts_upstream_of_or_within GO:0070207 protein homotrimerization PMID:17015441 IDA NCBITaxon:10090 UniProtKB:Q8R4D5 20081229 mgi:HJD PR:Q8R523-1 potassium voltage-gated channel subfamily G member 3 isoform 1 (rat) potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (rat)|rKCNG3/iso:1 acts_upstream_of_or_within GO:0006813 potassium ion transport PMID:15046870 IDA NCBITaxon:10116 UniProtKB:Q8R523-1 20080601 PRO:CNA PR:Q8R523-1 potassium voltage-gated channel subfamily G member 3 isoform 1 (rat) potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (rat)|rKCNG3/iso:1 contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:15046870 IDA NCBITaxon:10116 UniProtKB:Q8R523-1 20080601 PRO:CNA PR:Q8R523-2 potassium voltage-gated channel subfamily G member 3 isoform 2 (rat) potassium voltage-gated channel subfamily G member 3 isoform Kv10.1a (rat)|rKCNG3/iso:2 enables GO:0005249 voltage-gated potassium channel activity PMID:15046870 IDA NCBITaxon:10116 UniProtKB:Q8R523-2 20080601 PRO:CNA PR:Q8R523-2 potassium voltage-gated channel subfamily G member 3 isoform 2 (rat) potassium voltage-gated channel subfamily G member 3 isoform Kv10.1a (rat)|rKCNG3/iso:2 acts_upstream_of_or_within GO:0006813 potassium ion transport PMID:15046870 IDA NCBITaxon:10116 UniProtKB:Q8R523-2 20080601 PRO:CNA PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 located_in GO:0001726 ruffle MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080811 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 located_in GO:0030027 lamellipodium MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 acts_upstream_of_or_within GO:0008360 regulation of cell shape MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 acts_upstream_of_or_within GO:0030336 negative regulation of cell migration MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 acts_upstream_of_or_within GO:0035021 negative regulation of Rac protein signal transduction MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse) mARAP3/iso:1 acts_upstream_of_or_within GO:0035024 negative regulation of Rho protein signal transduction MGI_ref:3511766|PMID:15546919 IDA NCBITaxon:10090 MGI:2147274 20080807 MGI:MGI PR:Q8R5M8-2 cell adhesion molecule 1 isoform 2 (mouse) Cadm1c (mouse)|cell adhesion molecule 1 isoform c (mouse)|mCADM1/iso:2 located_in GO:0070852 cell body fiber MGI_ref:5009720|PMID:21482734 IDA NCBITaxon:10090 MGI:1889272 20141125 MGI:MGI part_of(CL:0000540) PR:Q8R5M8-3 cell adhesion molecule 1 isoform 3 (mouse) Cadm1b (mouse)|cell adhesion molecule 1 isoform b (mouse)|mCADM1/iso:3 located_in GO:0070852 cell body fiber MGI_ref:5009720|PMID:21482734 IDA NCBITaxon:10090 MGI:1889272 20141125 MGI:MGI part_of(CL:0000540) PR:Q8R5M8-4 cell adhesion molecule 1 isoform 4 (mouse) Cadm1d (mouse)|cell adhesion molecule 1 isoform d (mouse)|mCADM1/iso:4 located_in GO:0043196 varicosity MGI_ref:5009720|PMID:21482734 IDA NCBITaxon:10090 MGI:1889272 20141125 MGI:MGI part_of(CL:0000540) PR:Q8TAE7-1 potassium voltage-gated channel subfamily G member 3 isoform 1 (human) hKCNG3/iso:1|potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (human) located_in GO:0005783 endoplasmic reticulum PMID:12060745 IDA NCBITaxon:9606 UniProtKB:Q8TAE7-1 20080601 PRO:CNA PR:Q8TAE7-1 potassium voltage-gated channel subfamily G member 3 isoform 1 (human) hKCNG3/iso:1|potassium voltage-gated channel subfamily G member 3 isoform Kv10.1b (human) located_in GO:0005886 plasma membrane PMID:12060745 IDA NCBITaxon:9606 UniProtKB:Q8TAE7-1 20080601 PRO:CNA PR:Q8VCD5-1 mediator of RNA polymerase II transcription subunit 17 isoform 1 (mouse) mMED17/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:2182585 20120523 MGI:MGI PR:Q8VCD5-1 mediator of RNA polymerase II transcription subunit 17 isoform 1 (mouse) mMED17/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 UniProtKB:Q8VCD5-1 20120523 PRO:HJD PR:Q8VCQ6-1 phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform 1 (mouse) mSGMS1/iso:1|SMS1-alpha (mouse) acts_upstream_of_or_within GO:2001237 negative regulation of extrinsic apoptotic signaling pathway MGI_ref:3609513|PMID:16226406 IDA NCBITaxon:10090 MGI:2444110 20130621 MGI:MGI PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) enables GO:0005515 protein binding PR:P35564 MGI_ref:5288282|PMID:21747946 IPI NCBITaxon:10090 MGI:1920344 20130402 MGI:MGI PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) enables GO:0005515 protein binding PR:P42567 MGI_ref:4887327|PMID:17626015 IPI NCBITaxon:10090 MGI:1920344 20130401 MGI:MGI PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) enables GO:0005543 phospholipid binding MGI_ref:4887327|PMID:17626015 IDA NCBITaxon:10090 MGI:1920344 20140325 MGI:MGI PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) enables GO:0015631 tubulin binding PR:000044789 MGI_ref:4887327|PMID:17626015 IPI NCBITaxon:10090 MGI:1920344 20140325 MGI:MGI binding between proteins from heterogeneous species; tubulin isotype not specified PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) located_in GO:0030136 clathrin-coated vesicle MGI_ref:4887327|PMID:17626015 IDA NCBITaxon:10090 MGI:1920344 20140325 MGI:MGI part_of(CL:0000031) PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) acts_upstream_of_or_within GO:0048260 positive regulation of receptor-mediated endocytosis MGI_ref:4887327|PMID:17626015 IMP NCBITaxon:10090 MGI:1920344 20140325 MGI:MGI occurs_in(CL:0000031) PR:Q8VD37-6 SH3-containing GRB2-like protein 3-interacting protein 1 isoform 4 (mouse) mSGIP1/iso:4|SGIP1 alpha (mouse)|SGIP1a (mouse) acts_upstream_of_or_within GO:0097320 plasma membrane tubulation MGI_ref:4887327|PMID:17626015 IDA NCBITaxon:10090 MGI:1920344 20140325 MGI:MGI PR:Q8VHN7 adhesion G-protein coupled receptor V1 (mouse) Adgrv1|ADGRV1 (mouse)|G-protein coupled receptor 98 (mouse)|Gpr98|Kiaa0686|mAdgrv1|Mass1|mGpr98|monogenic audiogenic seizure susceptibility protein 1 (mouse)|neurepin (mouse)|protein rueda (mouse)|very large G-protein coupled receptor 1 (mouse)|Vlgr1|VLGR1 (mouse) located_in GO:0002141 stereocilia ankle link MGI_ref:3718182|PMID:17295842 IDA NCBITaxon:10090 MGI:1274784 20150415 MGI:MGI part_of(MA:0000240) PR:Q8VHN7 adhesion G-protein coupled receptor V1 (mouse) Adgrv1|ADGRV1 (mouse)|G-protein coupled receptor 98 (mouse)|Gpr98|Kiaa0686|mAdgrv1|Mass1|mGpr98|monogenic audiogenic seizure susceptibility protein 1 (mouse)|neurepin (mouse)|protein rueda (mouse)|very large G-protein coupled receptor 1 (mouse)|Vlgr1|VLGR1 (mouse) acts_upstream_of_or_within GO:0007605 sensory perception of sound MGI_ref:3718182|PMID:17295842 IMP NCBITaxon:10090 MGI_allele:3718538 MGI:1274784 20150415 MGI:MGI occurs_in(MA:0000240) PR:Q8VHN7 adhesion G-protein coupled receptor V1 (mouse) Adgrv1|ADGRV1 (mouse)|G-protein coupled receptor 98 (mouse)|Gpr98|Kiaa0686|mAdgrv1|Mass1|mGpr98|monogenic audiogenic seizure susceptibility protein 1 (mouse)|neurepin (mouse)|protein rueda (mouse)|very large G-protein coupled receptor 1 (mouse)|Vlgr1|VLGR1 (mouse) acts_upstream_of_or_within GO:0007605 sensory perception of sound MGI_ref:3718182|PMID:17295842 IMP NCBITaxon:10090 MGI_allele:3527179 MGI:1274784 20150415 MGI:MGI PR:Q8VHN7 adhesion G-protein coupled receptor V1 (mouse) Adgrv1|ADGRV1 (mouse)|G-protein coupled receptor 98 (mouse)|Gpr98|Kiaa0686|mAdgrv1|Mass1|mGpr98|monogenic audiogenic seizure susceptibility protein 1 (mouse)|neurepin (mouse)|protein rueda (mouse)|very large G-protein coupled receptor 1 (mouse)|Vlgr1|VLGR1 (mouse) acts_upstream_of_or_within GO:0060122 inner ear receptor cell stereocilium organization MGI_ref:3718182|PMID:17295842 IMP NCBITaxon:10090 MGI_allele:3718538 MGI:1274784 20150415 MGI:MGI occurs_in(MA:0000240) PR:Q8VIM5-1 myocardin isoform 1 (mouse) mMYOCD/iso:1|MYOCD-v2 (mouse) acts_upstream_of_or_within GO:0051091 positive regulation of DNA-binding transcription factor activity MGI_ref:4819920|PMID:20385216 IDA NCBITaxon:10090 MGI:2137495 20150408 MGI:MGI PR:Q8VIM5-3 myocardin isoform 3 (mouse) mMYOCD/iso:3|Myocardin A (mouse)|MYOCD-v1 (mouse) acts_upstream_of_or_within GO:0051091 positive regulation of DNA-binding transcription factor activity MGI_ref:4819920|PMID:20385216 IDA NCBITaxon:10090 MGI:2137495 20150408 MGI:MGI PR:Q8VIM5-4 myocardin isoform 4 (mouse) mMYOCD/iso:4|MYOCD-v3 (mouse) acts_upstream_of_or_within GO:0051091 positive regulation of DNA-binding transcription factor activity MGI_ref:4819920|PMID:20385216 IDA NCBITaxon:10090 MGI:2137495 20150408 MGI:MGI PR:Q8VZ91 ethylene-responsive transcription factor 6 (Arabidopsis thaliana) At-ERF6|At4g17490|AtERF6|dl4780c|EREBP-6 (Arabidopsis thaliana)|ERF-6|ERF103|ERF6|ethylene-responsive element-binding factor 6 (Arabidopsis thaliana)|FCAALL.120 located_in GO:0005634 nucleus PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91 20140402 PRO:LVM PR:Q8VZ91 ethylene-responsive transcription factor 6 (Arabidopsis thaliana) At-ERF6|At4g17490|AtERF6|dl4780c|EREBP-6 (Arabidopsis thaliana)|ERF-6|ERF103|ERF6|ethylene-responsive element-binding factor 6 (Arabidopsis thaliana)|FCAALL.120 located_in GO:0005737 cytoplasm PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91 20140402 PRO:LVM PR:Q8VZ91 ethylene-responsive transcription factor 6 (Arabidopsis thaliana) At-ERF6|At4g17490|AtERF6|dl4780c|EREBP-6 (Arabidopsis thaliana)|ERF-6|ERF103|ERF6|ethylene-responsive element-binding factor 6 (Arabidopsis thaliana)|FCAALL.120 acts_upstream_of_or_within GO:1900409 positive regulation of cellular response to oxidative stress PMID:23300166 EXP NCBITaxon:3702 UniProtKB:Q8VZ91 20140402 PRO:LVM PR:Q8WV44-2 E3 ubiquitin-protein ligase TRIM41 isoform 2 (human) hTRIM41/iso:2|RINCK1 (human)|TRIM41b (human)|TRIM41beta (human) enables GO:0005515 protein binding PR:P68403-2 PMID:17893151 IPI NCBITaxon:9606 UniProtKB:Q8WV44-2 20110116 GOA:IntAct PR:Q8WWW0-2 Ras association domain-containing protein 5 isoform 2 (human) hRASSF5/iso:2 enables GO:0005515 protein binding PR:P62834 PMID:15569673 IPI NCBITaxon:9606 UniProtKB:Q8WWW0-2 20110116 GOA:IntAct PR:Q8WWW0-2 Ras association domain-containing protein 5 isoform 2 (human) hRASSF5/iso:2 enables GO:0005515 protein binding PR:Q13043 PMID:16892067 IPI NCBITaxon:9606 UniProtKB:Q8WWW0-2 20110116 GOA:IntAct PR:Q8WXH0-4 nesprin-2 isoform 4 (human) hSYNE2/iso:4 enables GO:0005515 protein binding PR:Q9D666 PMID:19933576 IPI NCBITaxon:9606 UniProtKB:Q8WXH0-4 20100203 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:Q8WXH0-5 nesprin-2 isoform 5 (human) hSYNE2/iso:5 enables GO:0005515 protein binding PR:Q9D666 PMID:19933576 IPI NCBITaxon:9606 UniProtKB:Q8WXH0-5 20100203 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:Q8WXH0-5 nesprin-2 isoform 5 (human) hSYNE2/iso:5 enables GO:0005515 protein binding PR:Q9UH99 PMID:19933576 IPI NCBITaxon:9606 UniProtKB:Q8WXH0-5 20100203 GOA:UniProtKB Note=Annotation from GAF, isoform mapped to PRO PR:Q91V14-1 solute carrier family 12 member 5 isoform 1 (mouse) KCC2a (mouse)|mSLC12A5/iso:1 enables GO:0005515 protein binding PR:Q91V14-1 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-1 solute carrier family 12 member 5 isoform 1 (mouse) KCC2a (mouse)|mSLC12A5/iso:1 enables GO:0005515 protein binding PR:Q91V14-1|PR:Q91V14-2 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-1 solute carrier family 12 member 5 isoform 1 (mouse) KCC2a (mouse)|mSLC12A5/iso:1 enables GO:0005515 protein binding PR:Q91V14-2 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-1 solute carrier family 12 member 5 isoform 1 (mouse) KCC2a (mouse)|mSLC12A5/iso:1 located_in GO:0043025 neuronal cell body MGI_ref:3849365|PMID:19307176 IDA NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI part_of(CL:0000117) PR:Q91V14-1 solute carrier family 12 member 5 isoform 1 (mouse) KCC2a (mouse)|mSLC12A5/iso:1 located_in GO:0043198 dendritic shaft MGI_ref:3849365|PMID:19307176 IDA NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI part_of(CL:0000117) PR:Q91V14-2 solute carrier family 12 member 5 isoform 2 (mouse) KCC2b (mouse)|mSLC12A5/iso:2 enables GO:0005515 protein binding PR:Q91V14-1 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-2 solute carrier family 12 member 5 isoform 2 (mouse) KCC2b (mouse)|mSLC12A5/iso:2 enables GO:0005515 protein binding PR:Q91V14-1|PR:Q91V14-2 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-2 solute carrier family 12 member 5 isoform 2 (mouse) KCC2b (mouse)|mSLC12A5/iso:2 enables GO:0005515 protein binding PR:Q91V14-2 MGI_ref:3849365|PMID:19307176 IPI NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91V14-2 solute carrier family 12 member 5 isoform 2 (mouse) KCC2b (mouse)|mSLC12A5/iso:2 located_in GO:0043025 neuronal cell body MGI_ref:3849365|PMID:19307176 IDA NCBITaxon:10090 MGI:1862037 20121114 MGI:MGI PR:Q91WD2 transient receptor potential cation channel subfamily V member 6 (mouse) calcium transport protein 1 (mouse)|CaT1 (mouse)|ECaC2 (mouse)|epithelial calcium channel 2 (mouse)|mTRPV6|Trpv6|TrpV6 (mouse) enables GO:0005262 calcium channel activity PMID:12077127 IDA NCBITaxon:10090 UniProtKB:Q91WD2 20080601 PRO:CNA PR:Q91WD2 transient receptor potential cation channel subfamily V member 6 (mouse) calcium transport protein 1 (mouse)|CaT1 (mouse)|ECaC2 (mouse)|epithelial calcium channel 2 (mouse)|mTRPV6|Trpv6|TrpV6 (mouse) acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:12077127 IDA NCBITaxon:10090 UniProtKB:Q91WD2 20080601 PRO:CNA PR:Q91WG4-1 elongator complex protein 2 isoform 1 (mouse) mELP2/iso:1 enables GO:0005515 protein binding PR:P42227 MGI_ref:1889079|PMID:10954736 IPI NCBITaxon:10090 MGI:1889642 20050818 MGI:MGI PR:Q91WP0-1 mannan-binding lectin serine protease 2 isoform 1 (mouse) Masp2a (mouse)|mMASP2/iso:1 enables GO:0005515 protein binding PR:O70165-1 MGI_ref:5473786|PMID:16328467 IPI NCBITaxon:10090 MGI:1330832 20140401 MGI:MGI PR:Q91WP0-1 mannan-binding lectin serine protease 2 isoform 1 (mouse) Masp2a (mouse)|mMASP2/iso:1 acts_upstream_of_or_within GO:0001867 complement activation, lectin pathway MGI_ref:5473786|PMID:16328467 IDA NCBITaxon:10090 MGI:1330832 20131022 MGI:MGI PR:Q91WP0-2 mannan-binding lectin serine protease 2 isoform 2 (mouse) mMASP2/iso:2 enables GO:0005515 protein binding PR:O70165-1 MGI_ref:5473786|PMID:16328467 IPI NCBITaxon:10090 MGI:1330832 20140401 MGI:MGI PR:Q91XP5-1 glycine receptor subunit alpha-3 isoform Alpha-3L (mouse) glycine receptor subunit alpha-3 isoform 1 (mouse)|GlyR alpha3L|mGLRA3/iso:1 located_in GO:0009897 external side of plasma membrane MGI_ref:4365666|PMID:19723286 IDA NCBITaxon:10090 MGI:95749 20141021 MGI:MGI occurs_in(CLO:0000019) PR:Q91XP5-1 glycine receptor subunit alpha-3 isoform Alpha-3L (mouse) glycine receptor subunit alpha-3 isoform 1 (mouse)|GlyR alpha3L|mGLRA3/iso:1 located_in GO:0043679 axon terminus MGI_ref:4365666|PMID:19723286 IDA NCBITaxon:10090 MGI:95749 20141021 MGI:MGI occurs_in(CL:0002608) PR:Q91XP5-1 glycine receptor subunit alpha-3 isoform Alpha-3L (mouse) glycine receptor subunit alpha-3 isoform 1 (mouse)|GlyR alpha3L|mGLRA3/iso:1 acts_upstream_of_or_within GO:0043113 receptor clustering MGI_ref:4365666|PMID:19723286 IMP NCBITaxon:10090 MGI:95749 20150127 MGI:MGI occurs_in(CL:0002608) PR:Q91XP5-1 glycine receptor subunit alpha-3 isoform Alpha-3L (mouse) glycine receptor subunit alpha-3 isoform 1 (mouse)|GlyR alpha3L|mGLRA3/iso:1 acts_upstream_of_or_within GO:0072578 neurotransmitter-gated ion channel clustering MGI_ref:4365666|PMID:19723286 IMP NCBITaxon:10090 MGI:95749 20150127 MGI:MGI occurs_in(MA:0000191) PR:Q91XP5-1 glycine receptor subunit alpha-3 isoform Alpha-3L (mouse) glycine receptor subunit alpha-3 isoform 1 (mouse)|GlyR alpha3L|mGLRA3/iso:1 acts_upstream_of_or_within GO:0097112 gamma-aminobutyric acid receptor clustering MGI_ref:4365666|PMID:19723286 IGI NCBITaxon:10090 MGI:95751 MGI:95749 20150127 MGI:MGI occurs_in(CL:0002608) PR:Q91XQ0-1 dynein axonemal heavy chain 8 isoform 1 (mouse) mDNAH8/iso:1 located_in GO:0097228 sperm principal piece MGI_ref:3604434|PMID:16054618 IDA NCBITaxon:10090 MGI:107714 20140331 MGI:MGI part_of(CL:0000019) PR:Q91ZR5 cation channel sperm-associated protein 1 (mouse) Catsper1|CatSper1 (mouse)|mCATSPER1 acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:11595941 IDA NCBITaxon:10090 UniProtKB:Q91ZR5 20080601 PRO:CNA PR:Q91ZR5 cation channel sperm-associated protein 1 (mouse) Catsper1|CatSper1 (mouse)|mCATSPER1 acts_upstream_of_or_within GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization PMID:11595941 IDA NCBITaxon:10090 UniProtKB:Q91ZR5 20080601 PRO:CNA PR:Q91ZR5 cation channel sperm-associated protein 1 (mouse) Catsper1|CatSper1 (mouse)|mCATSPER1 acts_upstream_of_or_within GO:0030317 flagellated sperm motility PMID:11595941 IDA NCBITaxon:10090 UniProtKB:Q91ZR5 20080601 PRO:CNA PR:Q91ZR5-1 cation channel sperm-associated protein 1 isoform 1 (mouse) mCATSPER1/iso:1 enables GO:0005515 protein binding PR:Q80W99-1 PMID:17227845 IPI NCBITaxon:10090 UniProtKB:Q91ZR5-1 20080601 PRO:CNA PR:Q91ZR5-1 cation channel sperm-associated protein 1 isoform 1 (mouse) mCATSPER1/iso:1 located_in GO:0005886 plasma membrane PMID:11595941 IDA NCBITaxon:10090 UniProtKB:Q91ZR5-1 20080601 PRO:CNA PR:Q91ZR5-1 cation channel sperm-associated protein 1 isoform 1 (mouse) mCATSPER1/iso:1 part_of GO:0032991 protein-containing complex PMID:17478420 IDA NCBITaxon:10090 PR:000002588 UniProtKB:Q91ZR5-1 20080601 PRO:CNA PR:Q91ZU6-1 dystonin isoform 2 (mouse) dystonin isoform BPAG1-b (mouse)|dystonin isoform BPAG1a1 (mouse)|dystonin isoform dystonin-1 (mouse)|mDST/iso:2 located_in GO:0015629 actin cytoskeleton MGI_ref:1341473|PMID:10428034 IDA NCBITaxon:10090 MGI:96083 MGI:104627 20080807 MGI:MGI PR:Q91ZU6-2 dystonin isoform 1 (mouse) dystonin isoform BPAG1-a (mouse)|dystonin isoform BPAG1a2 (mouse)|mDST/iso:1 located_in GO:0015629 actin cytoskeleton MGI_ref:1341473|PMID:10428034 IDA NCBITaxon:10090 MGI:104771 MGI:104627 20140325 MGI:MGI PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse) mSENP2/iso:1 enables GO:0016929 deSUMOylase activity MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse) mSENP2/iso:1 located_in GO:0005634 nucleus MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse) mSENP2/iso:1 acts_upstream_of_or_within GO:0016926 protein desumoylation MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse) mSENP2/iso:1 acts_upstream_of_or_within GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse) mSENP2/iso:1 acts_upstream_of_or_within GO:1901797 negative regulation of signal transduction by p53 class mediator MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-2 sentrin-specific protease 2 isoform 2 (mouse) mSENP2/iso:2|Senp2-M (mouse) located_in GO:0031410 cytoplasmic vesicle MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q91ZX6-3 sentrin-specific protease 2 isoform 3 (mouse) mSENP2/iso:3|Senp2-S (mouse) located_in GO:0005737 cytoplasm MGI_ref:5433829|PMID:21183956 IDA NCBITaxon:10090 MGI:1923076 20140523 MGI:MGI PR:Q920D3-1 mediator of RNA polymerase II transcription subunit 28 isoform 1 (mouse) mMED28/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1914249 20120523 MGI:MGI PR:Q920M9-1 E3 ubiquitin-protein ligase SIAH1 isoform 1 (rat) rSIAH1/iso:1 enables GO:0005515 protein binding PR:Q71F54 PMID:16230351 IPI NCBITaxon:10116 UniProtKB:Q920M9-1 20100515 PRO:JAN PR:Q921D4-1 mediator of RNA polymerase II transcription subunit 6 isoform 1 (mouse) mMED6/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1917042 20120523 MGI:MGI PR:Q924H2-1 mediator of RNA polymerase II transcription subunit 15 isoform 1 (mouse) mMED15/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 TAS NCBITaxon:10090 MGI:2137379 20120523 MGI:MGI PR:Q925J9-1 mediator of RNA polymerase II transcription subunit 1 isoform 1 (mouse) mMED1/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1100846 20120523 MGI:MGI PR:Q925P2-2 carcinoembryonic antigen-related cell adhesion molecule 2 isoform 2 (mouse) Bgp2/2L (mouse)|mCeacam2/iso:2 located_in GO:0009986 cell surface MGI_ref:5451130|PMID:23070997 IDA NCBITaxon:10090 MGI:1347246 20130911 MGI:MGI part_of(CL:0000018) PR:Q925P2-3 carcinoembryonic antigen-related cell adhesion molecule 2 isoform 3 (mouse) Bgp2/2S (mouse)|mCeacam2/iso:3 located_in GO:0009897 external side of plasma membrane MGI_ref:5503958|PMID:10491101 IDA NCBITaxon:10090 MGI:1347246 20130905 MGI:MGI PR:Q925P2-3 carcinoembryonic antigen-related cell adhesion molecule 2 isoform 3 (mouse) Bgp2/2S (mouse)|mCeacam2/iso:3 NOT acts_upstream_of_or_within GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules MGI_ref:5503958|PMID:10491101 IDA NCBITaxon:10090 MGI:1347246 20130904 MGI:MGI PR:Q925S4-1 interleukin-24 isoform 1 (mouse) FISP (mouse)|mIL24/iso:1 enables GO:0005515 protein binding PR:A3QQZ3 MGI_ref:3821693|PMID:18708357 IPI NCBITaxon:10090 MGI:2135548 20121120 MGI:MGI PR:Q925S4-1 interleukin-24 isoform 1 (mouse) FISP (mouse)|mIL24/iso:1 located_in GO:0005576 extracellular region MGI_ref:3821693|PMID:18708357 IDA NCBITaxon:10090 MGI:2135548 20121120 MGI:MGI PR:Q925S4-1 interleukin-24 isoform 1 (mouse) FISP (mouse)|mIL24/iso:1 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation MGI_ref:3821693|PMID:18708357 IDA NCBITaxon:10090 MGI:2135548 20121120 MGI:MGI PR:Q925T6-2 glutamate receptor-interacting protein 1 isoform 2 (mouse) GRIP1b (mouse)|GRIP1b-S (mouse)|mGRIP1/iso:2 located_in GO:0030425 dendrite MGI_ref:5315188|PMID:22325201 IDA NCBITaxon:10090 MGI:1921303 20121214 MGI:MGI part_of(CL:0002608) PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0003713 transcription coactivator activity PMID:10733899|PMID:10893273|PMID:12169688|PMID:12586840|PMID:8684459 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0004402 histone acetyltransferase activity PMID:11742995 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:P04637 PMID:9194564 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:P17096 PMID:10428834 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:P42858 PMID:10823891 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:P55209 PMID:11940655 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q04206 PMID:16291753 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q14686 PMID:10866662 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q16665 PMID:9887100 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q92793 PMID:8684459 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q99967-1 PMID:99104162 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0005515 protein binding PR:Q9UER7 PMID:11799127 IPI NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 enables GO:0016407 acetyltransferase activity PMID:11742995 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 located_in GO:0005634 nucleus PMID:7913207 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 part_of GO:0000123 histone acetyltransferase complex PMID:9742083 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12169688|PMID:7913207 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92793-1 CREB-binding protein isoform 1 (human) hCREBBP/iso:1 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:11742995 IDA NCBITaxon:9606 UniProtKB:Q92793-1 20080301 PRO:CNA PR:Q92900-2 regulator of nonsense transcripts 1 isoform 2 (human) hUPF1/iso:2 enables GO:0005515 protein binding PR:Q14152 PMID:18423202 IPI NCBITaxon:9606 UniProtKB:Q92900-2 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:Q92952-2 small conductance calcium-activated potassium channel protein 1 isoform 2 (human) hKCNN1/iso:2 enables GO:0005516 calmodulin binding PMID:10026195 IDA NCBITaxon:9606 UniProtKB:Q92952-2 20080601 PRO:CNA PR:Q92952-2 small conductance calcium-activated potassium channel protein 1 isoform 2 (human) hKCNN1/iso:2 acts_upstream_of_or_within GO:0007268 chemical synaptic transmission PMID:8781233 IDA NCBITaxon:9606 UniProtKB:Q92952-2 20080601 PRO:CNA PR:Q92953-1 potassium voltage-gated channel subfamily B member 2 isoform 1 (human) hKCNB2/iso:1 acts_upstream_of_or_within GO:0006940 regulation of smooth muscle contraction PMID:9612272 IDA NCBITaxon:9606 UniProtKB:Q92953-1 20080601 PRO:CNA PR:Q92953-1 potassium voltage-gated channel subfamily B member 2 isoform 1 (human) hKCNB2/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:9612272 IDA NCBITaxon:9606 UniProtKB:Q92953-1 20080601 PRO:CNA PR:Q941L3 protein BONZAI 1 (Arabidopsis thaliana) At-BON1|At5g61900|BON1|COPINE 1 (Arabidopsis thaliana)|CPN1|K22G18.2 enables GO:0005515 protein binding PR:Q9SKB2 PMID:21623975 IPI NCBITaxon:3702 UniProtKB:Q941L3 20130412 PRO:LVM Note=In vitro experiment. PR:Q94F62 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 (Arabidopsis thaliana) At-plantBAK1|At4g33430|AtBAK1|AtSERK3|BAK1|BRI1-associated receptor kinase 1 (Arabidopsis thaliana)|ELG|F17M5.190|protein ELONGATED (Arabidopsis thaliana)|SERK3|somatic embryogenesis receptor kinase 3 (Arabidopsis thaliana)|somatic embryogenesis receptor-like kinase 3 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:21350342 EXP NCBITaxon:3702 UniProtKB:Q94F62 20130430 PRO:LVM PR:Q94F62-1 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 (Arabidopsis thaliana) At-plantBAK1/iso:1 enables GO:0004672 protein kinase activity PMID:21593986 EXP NCBITaxon:3702 UniProtKB:Q94F62-1 20130206 PRO:CNA Target=PR:000028471. Target=PR:000028476. PR:Q94F62-1 BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform 1 (Arabidopsis thaliana) At-plantBAK1/iso:1 enables GO:0004672 protein kinase activity PMID:21623975 EXP NCBITaxon:3702 UniProtKB:Q94F62-1 20130206 PRO:CNA Target=PR:000028486. Target=PR:000028491. PR:Q96B01-2 RAD51-associated protein 1 isoform 2 (human) hRAD51AP1/iso:2 enables GO:0005515 protein binding PR:Q06609 PMID:9396801 IPI NCBITaxon:9606 UniProtKB:Q96B01-2 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:Q96B01-3 RAD51-associated protein 1 isoform 3 (human) hRAD51AP1/iso:3 enables GO:0005515 protein binding PR:Q06609 PMID:9396801 IPI NCBITaxon:9606 UniProtKB:Q96B01-3 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:Q96CA5-2 baculoviral IAP repeat-containing protein 7 isoform 1 (human) baculoviral IAP repeat-containing protein 7 isoform Livin beta (human)|hBIRC7/iso:1 enables GO:0005515 protein binding PR:P55211 PMID:11084335 IPI NCBITaxon:9606 UniProtKB:Q96CA5-2 20090918 PRO:JAN PR:Q96CA5-2 baculoviral IAP repeat-containing protein 7 isoform 1 (human) baculoviral IAP repeat-containing protein 7 isoform Livin beta (human)|hBIRC7/iso:1 enables GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process PMID:11084335 EXP NCBITaxon:9606 UniProtKB:Q96CA5-2 20090918 PRO:JAN PR:Q96CA5-2 baculoviral IAP repeat-containing protein 7 isoform 1 (human) baculoviral IAP repeat-containing protein 7 isoform Livin beta (human)|hBIRC7/iso:1 located_in GO:0005737 cytoplasm PMID:11084335 EXP NCBITaxon:9606 UniProtKB:Q96CA5-2 20090918 PRO:JAN PR:Q96CA5-2 baculoviral IAP repeat-containing protein 7 isoform 1 (human) baculoviral IAP repeat-containing protein 7 isoform Livin beta (human)|hBIRC7/iso:1 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:11084335 EXP NCBITaxon:9606 UniProtKB:Q96CA5-2 20090918 PRO:JAN PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0004672 protein kinase activity PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:O15392 BioGRID:BG-571501|IntAct:EBI-979359|MINT:MINT-4509558 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:O60566 BioGRID:BG-717913 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:P06493 IntAct:EBI-1397755 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:P68431 BioGRID:BG-530650 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q12834 BioGRID:BG-684898 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q13043 PMID:20171103 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q15208 PMID:20171103 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q53HL2 BioGRID:BG-251030 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q71DI3 BioGRID:BG-725715 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 enables GO:0005515 protein binding PR:Q9NQS7 BioGRID:BG-251075|IntAct:EBI-1555366|MINT:MINT-77928 IPI NCBITaxon:9606 UniProtKB:Q96GD4 20130103 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Target=PR:Q5FBB7. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 located_in GO:0000779 condensed chromosome, centromeric region PMID:12719470|PMID:15917996 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Timing=prometaphase, metaphase. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 located_in GO:0000939 inner kinetochore PMID:15592459 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 located_in GO:0030496 midbody PMID:15917996 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Timing=telophase. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 located_in GO:0051233 spindle midzone PMID:15917996 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Timing=anaphase. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0007059 chromosome segregation PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:12719470|PMID:15592459 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12719470|PMID:17617734|PMID:22732840 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Target=PR:O60566. Target=PR:Q02224. Target=PR:Q13257. Target=PR:O43683. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0051310 metaphase chromosome alignment PMID:12719470|PMID:22732840 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0071459 protein localization to chromosome, centromeric region PMID:12719470|PMID:21658950 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER Target=PR:O15392. Target=PR:Q96GD4. PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 acts_upstream_of_or_within GO:0140014 mitotic nuclear division PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96GD4 aurora kinase B (human) AIK2|AIM-1 (human)|AIM1|AIRK2|ARK-2 (human)|ARK2|AURKB|aurora 1 (human)|aurora- and IPL1-like midbody-associated protein 1 (human)|aurora-related kinase 2 (human)|aurora/IPL1-related kinase 2 (human)|hAURKB|serine/threonine-protein kinase 12 (human)|serine/threonine-protein kinase 5 (human)|serine/threonine-protein kinase aurora-B (human)|STK-1 (human)|STK1|STK12|STK5 NOT acts_upstream_of_or_within GO:0051306 mitotic sister chromatid separation PMID:12719470 EXP NCBITaxon:9606 UniProtKB:Q96GD4 20121023 PRO:KER PR:Q96KK3-1 potassium voltage-gated channel subfamily S member 1 isoform 1 (human) hKCNS1/iso:1 enables GO:0015459 potassium channel regulator activity PMID:10484328 IDA NCBITaxon:9606 UniProtKB:Q96KK3-1 20080601 PRO:CNA PR:Q96KK3-1 potassium voltage-gated channel subfamily S member 1 isoform 1 (human) hKCNS1/iso:1 located_in GO:0005886 plasma membrane PMID:10484328 IDA NCBITaxon:9606 UniProtKB:Q96KK3-1 20080601 PRO:CNA PR:Q96KK3-1 potassium voltage-gated channel subfamily S member 1 isoform 1 (human) hKCNS1/iso:1 contributes_to enables GO:0005251 delayed rectifier potassium channel activity PMID:10484328 IDA NCBITaxon:9606 UniProtKB:Q96KK3-1 20080601 PRO:CNA PR:Q96L42 potassium voltage-gated channel subfamily H member 8 (human) ELK channel 3 (human)|ELK1 (human)|ELK3 (human)|ether-a-go-go-like potassium channel 3 (human)|hElk1|hKCNH8|KCNH8|voltage-gated potassium channel subunit Kv12.1 (human) contributes_to enables GO:0005249 voltage-gated potassium channel activity PMID:12890647 IDA NCBITaxon:9606 UniProtKB:Q96L42 20080601 PRO:CNA PR:Q96P56-1 cation channel sperm-associated protein 2 isoform 1 (human) cation channel sperm-associated protein 2 isoform Variant 2 (human)|hCATSPER2/iso:1 enables GO:0005515 protein binding PR:Q9P0X4 PMID:16740636 IPI NCBITaxon:9606 UniProtKB:Q96P56-1 20080601 PRO:CNA PR:Q96QF0-1 Rab-3A-interacting protein isoform 1 (human) hRAB3IP/iso:1 enables GO:0005515 protein binding PR:Q8NFJ9 PMID:17574030 IPI NCBITaxon:9606 UniProtKB:Q96QF0-1 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 enables GO:0005515 protein binding PR:Q16385 PMID:12007189 IPI NCBITaxon:9606 UniProtKB:Q96QF0-2 20101213 GOA:IntAct Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 enables GO:0005515 protein binding PR:Q8NFJ9 PMID:17574030 IPI NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 located_in GO:0005813 centrosome PMID:17574030 IDA NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 located_in GO:0036064 ciliary basal body PMID:17574030 TAS NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 acts_upstream_of_or_within GO:0006893 Golgi to plasma membrane transport PMID:17574030 TAS NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 acts_upstream_of_or_within GO:0033365 protein localization to organelle PMID:17574030 IMP NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q96QF0-2 Rab-3A-interacting protein isoform 2 (human) hRAB3IP/iso:2 acts_upstream_of_or_within GO:0060271 cilium assembly PMID:17574030 IMP NCBITaxon:9606 UniProtKB:Q96QF0-2 20080521 GOA:BHF-UCL Note=Annotation from GAF, isoform mapped to PRO PR:Q98UH3 mitotic checkpoint serine/threonine-protein kinase BUB1 sequence variant 1 (frog) frog-BUB1/var:1 enables GO:0005515 protein binding PR:Q9YGY3 PMID:11231148 IPI NCBITaxon:8355 UniProtKB:Q98UH3 20120912 PRO:KER PR:Q98UH3 mitotic checkpoint serine/threonine-protein kinase BUB1 sequence variant 1 (frog) frog-BUB1/var:1 located_in GO:0000776 kinetochore PMID:11231148|PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q98UH3 20120912 PRO:KER Timing=Meiosis I, Meiosis II, Mitosis (prophase, metaphase, anaphase). PR:Q98UH3 mitotic checkpoint serine/threonine-protein kinase BUB1 sequence variant 1 (frog) frog-BUB1/var:1 located_in GO:0005694 chromosome PMID:15241477|PMID:16950116 EXP NCBITaxon:8355 UniProtKB:Q98UH3 20130102 PRO:KER PR:Q98UH3 mitotic checkpoint serine/threonine-protein kinase BUB1 sequence variant 1 (frog) frog-BUB1/var:1 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 EXP NCBITaxon:8355 UniProtKB:Q98UH3 20130102 PRO:KER Target=PR:Q8JGT8. PR:Q99232 CEACAM1b-2S (mouse) Bgp B (mouse)|Bgp1b/2S(mouse)|BgpB (mouse)|Ceacam1b/D1-2S (mouse)|mCEACAM1b/iso:2S|mmCGM2|mmCGM2(2d) acts_upstream_of_or_within GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules MGI_ref:59357|PMID:1985902 IDA NCBITaxon:10090 MGI:1347245 20150106 MGI:MGI PR:Q99583-1 Max-binding protein MNT isoform 1 (human) hMNT/iso:1 located_in GO:0005634 nucleus PMID:9184233 EXP NCBITaxon:9606 UniProtKB:Q99583-1 20101005 PRO:CNA PR:Q99697-1 pituitary homeobox 2 isoform Ptx2B (human) hPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (human) enables GO:0005515 protein binding PR:Q99697-2 PMID:11948188 IPI NCBITaxon:9606 UniProtKB:Q99697-1 20150223 PRO:CNA PR:Q99697-1 pituitary homeobox 2 isoform Ptx2B (human) hPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (human) enables GO:0005515 protein binding PR:Q99697-3 PMID:11948188 IPI NCBITaxon:9606 UniProtKB:Q99697-1 20150223 PRO:CNA PR:Q99697-1 pituitary homeobox 2 isoform Ptx2B (human) hPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (human) acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:9708732 IDA NCBITaxon:9606 UniProtKB:Q99697-1 20080301 PRO:CNA PR:Q99697-1 pituitary homeobox 2 isoform Ptx2B (human) hPITX2/iso:Ptx2B|pituitary homeobox 2 isoform ARP1B (human) acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:9618168 IDA NCBITaxon:9606 UniProtKB:Q99697-1 20080301 PRO:CNA PR:Q99697-2 pituitary homeobox 2 isoform Ptx2C (human) hPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (human) enables GO:0003677 DNA binding PMID:11948188 IDA NCBITaxon:9606 UniProtKB:Q99697-2 20080301 PRO:CNA PR:Q99697-2 pituitary homeobox 2 isoform Ptx2C (human) hPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (human) enables GO:0005515 protein binding PR:Q99697-1 PMID:11948188 IPI NCBITaxon:9606 UniProtKB:Q99697-2 20080301 PRO:CNA PR:Q99697-2 pituitary homeobox 2 isoform Ptx2C (human) hPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (human) enables GO:0005515 protein binding PR:Q99697-3 PMID:11948188 IPI NCBITaxon:9606 UniProtKB:Q99697-2 20080301 PRO:CNA PR:Q99697-2 pituitary homeobox 2 isoform Ptx2C (human) hPITX2/iso:Ptx2C|pituitary homeobox 2 isoform ARP1C (human) acts_upstream_of_or_within GO:0007507 heart development PMID:11948188 IDA NCBITaxon:9606 UniProtKB:Q99697-2 20080301 PRO:CNA PR:Q99697-3 pituitary homeobox 2 isoform Ptx2A (human) hPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (human) enables GO:0005515 protein binding PR:Q99697-2 PMID:11948188 IPI NCBITaxon:9606 UniProtKB:Q99697-3 20080301 PRO:CNA PR:Q99697-3 pituitary homeobox 2 isoform Ptx2A (human) hPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (human) enables GO:0008134 transcription factor binding PMID:16449236 IDA NCBITaxon:9606 UniProtKB:Q99697-3 20080301 PRO:CNA PR:Q99697-3 pituitary homeobox 2 isoform Ptx2A (human) hPITX2/iso:Ptx2A|pituitary homeobox 2 isoform ARP1A (human) located_in GO:0005634 nucleus PMID:16449236 IDA NCBITaxon:9606 UniProtKB:Q99697-3 20080301 PRO:CNA PR:Q99717-1 mothers against decapentaplegic homolog 5 isoform 1 (human) hSMAD5/iso:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135 IDA NCBITaxon:9606 UniProtKB:Q99717-1 20080301 PRO:CNA PR:Q99717-1 mothers against decapentaplegic homolog 5 isoform 1 (human) hSMAD5/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8673135 IDA NCBITaxon:9606 UniProtKB:Q99717-1 20080301 PRO:CNA PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 located_in GO:0030424 axon MGI_ref:1098517|PMID:1317267 IDA NCBITaxon:10090 MGI:2151253 20080811 MGI:MGI part_of(MA:0000694),part_of(CL:0000101) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 located_in GO:0043025 neuronal cell body MGI_ref:1316900|PMID:9838101 IDA NCBITaxon:10090 MGI:2151253 20080813 MGI:MGI part_of(MA:0000232),part_of(CL:0000101)|part_of(MA:0001119),part_of(CL:0000101) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0002027 regulation of heart rate MGI_ref:2445452|PMID:11717154 IMP NCBITaxon:10090 MGI_allele:2445489 MGI:2151253 20080811 MGI:MGI has_participant(MA:0000072) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0009408 response to heat MGI_ref:3603999|PMID:16118273 IMP NCBITaxon:10090 MGI:2151253 20080828 MGI:MGI PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0030279 negative regulation of ossification MGI_ref:3653805|PMID:15537449 IMP NCBITaxon:10090 MGI_allele:3527257 MGI:2151253 20080811 MGI:MGI regulates_o_occurs_in(MA:0000309) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0031645 negative regulation of nervous system process MGI_ref:2445452|PMID:11717154 IMP NCBITaxon:10090 MGI_allele:2445489 MGI:2151253 20080811 MGI:MGI regulates_o_has_participant(MA:0000225),regulates_o_has_participant(CL:0000700)|regulates_o_has_participant(MA:0000119),regulates_o_has_participant(CL:0000700) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0045776 negative regulation of blood pressure MGI_ref:2445452|PMID:11717154 IMP NCBITaxon:10090 MGI_allele:2445489 MGI:2151253 20080811 MGI:MGI has_participant(MA:0000064) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0045778 positive regulation of ossification MGI_ref:3653805|PMID:15537449 IMP NCBITaxon:10090 MGI_allele:2148538 MGI:2151253 20080811 MGI:MGI regulates_o_has_participant(MA:0000309) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 acts_upstream_of_or_within GO:0048265 response to pain MGI_ref:1933070|PMID:11276224 IMP NCBITaxon:10090 MGI_allele:2148771 MGI:2151253 20080811 MGI:MGI PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 NOT acts_upstream_of_or_within GO:0007528 neuromuscular junction development MGI_ref:1345568|PMID:10532808 IMP NCBITaxon:10090 MGI_allele:2148538 MGI:2151253 20080811 MGI:MGI has_participant(MA:0000165) PR:Q99JA0-1 calcitonin gene-related peptide 1 (mouse) mCALCA/iso:CGRP1 NOT acts_upstream_of_or_within GO:0008217 regulation of blood pressure MGI_ref:1345568|PMID:10532808 IMP NCBITaxon:10090 MGI_allele:2148538 MGI:2151253 20080829 MGI:MGI PR:Q99K74-1 mediator of RNA polymerase II transcription subunit 24 isoform 1 (mouse) mMED24/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1344385 20120523 MGI:MGI PR:Q99KP6-2 pre-mRNA-processing factor 19 isoform 2 (mouse) mPrpf19/iso:2 located_in GO:0005634 nucleus MGI_ref:3640624|PMID:16352598 IDA NCBITaxon:10090 MGI:106247 20070705 MGI:MGI PR:Q99KP6-2 pre-mRNA-processing factor 19 isoform 2 (mouse) mPrpf19/iso:2 located_in GO:0005737 cytoplasm MGI_ref:3640624|PMID:16352598 IDA NCBITaxon:10090 MGI:106247 20090410 MGI:MGI PR:Q99KP6-2 pre-mRNA-processing factor 19 isoform 2 (mouse) mPrpf19/iso:2 acts_upstream_of_or_within GO:0045665 negative regulation of neuron differentiation MGI_ref:3640624|PMID:16352598 IDA NCBITaxon:10090 MGI:106247 20090410 MGI:MGI PR:Q99KP6-2 pre-mRNA-processing factor 19 isoform 2 (mouse) mPrpf19/iso:2 acts_upstream_of_or_within GO:0048711 positive regulation of astrocyte differentiation MGI_ref:3640624|PMID:16352598 IDA NCBITaxon:10090 MGI:106247 20070705 MGI:MGI PR:Q99LC5-1 electron transfer flavoprotein subunit alpha, mitochondrial isoform 1 (mouse) mETFA/iso:1 located_in GO:0005739 mitochondrion MGI_ref:2682130|PMID:14651853 IDA NCBITaxon:10090 MGI:98368|MGI:98371 MGI:106092 20071029 MGI:MGI part_of(MA:0000358)|part_of(MA:0000168)|part_of(MA:0000368)|part_of(MA:0000072) PR:Q99LQ1-1 MAP3K12-binding inhibitory protein 1 isoform 1 (mouse) mMBIP/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1918320 20120611 MGI:MGI PR:Q99ML1-1 Bcl-2-binding component 3 isoform 1 (mouse) mBBC3/iso:1 enables GO:0005515 protein binding PR:P63168 PMID:10198631 IPI NCBITaxon:10090 UniProtKB:O54918-2 20090918 PRO:JAN PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse) ADAR p150 (mouse)|ADAR-a (mouse)|ADAR1Lb (mouse)|mADAR/iso:1 enables GO:0003726 double-stranded RNA adenosine deaminase activity MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse) ADAR p150 (mouse)|ADAR-a (mouse)|ADAR1Lb (mouse)|mADAR/iso:1 located_in GO:0005737 cytoplasm MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse) ADAR p150 (mouse)|ADAR-a (mouse)|ADAR1Lb (mouse)|mADAR/iso:1 acts_upstream_of_or_within GO:0001701 in utero embryonic development MGI_ref:4939544|PMID:21173229 IMP NCBITaxon:10090 MGI_allele:4941203 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse) ADAR p150 (mouse)|ADAR-a (mouse)|ADAR1Lb (mouse)|mADAR/iso:1 acts_upstream_of_or_within GO:0045071 negative regulation of viral genome replication MGI_ref:4939544|PMID:21173229 IMP NCBITaxon:10090 MGI_allele:4941203 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse) ADAR p150 (mouse)|ADAR-a (mouse)|ADAR1Lb (mouse)|mADAR/iso:1 acts_upstream_of_or_within GO:0051607 defense response to virus MGI_ref:4939544|PMID:21173229 IMP NCBITaxon:10090 MGI_allele:4941203 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-2 double-stranded RNA-specific adenosine deaminase isoform 2 (mouse) ADAR1La (mouse)|mADAR/iso:2 enables GO:0003726 double-stranded RNA adenosine deaminase activity MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-2 double-stranded RNA-specific adenosine deaminase isoform 2 (mouse) ADAR1La (mouse)|mADAR/iso:2 located_in GO:0005737 cytoplasm MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-3 double-stranded RNA-specific adenosine deaminase isoform 3 (mouse) ADAR1Sa (mouse)|mADAR/iso:3 enables GO:0003726 double-stranded RNA adenosine deaminase activity MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-3 double-stranded RNA-specific adenosine deaminase isoform 3 (mouse) ADAR1Sa (mouse)|mADAR/iso:3 located_in GO:0005730 nucleolus MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MU3-4 double-stranded RNA-specific adenosine deaminase isoform 4 (mouse) ADAR1 p80 (mouse)|ADAR1Sb (mouse)|mADAR/iso:4 enables GO:0003726 double-stranded RNA adenosine deaminase activity MGI_ref:5515381|PMID:12954622 IDA NCBITaxon:10090 MGI:1889575 20131029 MGI:MGI PR:Q99MZ3-1 carbohydrate-responsive element-binding protein isoform 1 (mouse) carbohydrate-responsive element-binding protein isoform Zeta (mouse)|mMLXIPL/iso:1 located_in GO:0005737 cytoplasm MGI_ref:5319432|PMID:22466288 IDA NCBITaxon:10090 MGI:1927999 20150122 MGI:MGI PR:Q99NH2-3 partitioning defective 3 homolog isoform 3 (mouse) mPARD3/iso:3|Par-3 100 kDA isoform located_in GO:0005938 cell cortex MGI_ref:3577813|PMID:15766746 IDA NCBITaxon:10090 MGI:2135608 20080811 MGI:MGI part_of(CL:0000655) PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 enables GO:0005515 protein binding PR:P10415 PMID:11463392 IPI NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 enables GO:0005515 protein binding PR:Q07817-1 PMID:11463391 IPI NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 located_in GO:0005739 mitochondrion PMID:11463391 EXP NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 located_in GO:0005739 mitochondrion PMID:11463392 EXP NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 acts_upstream_of_or_within GO:0001836 release of cytochrome c from mitochondria PMID:11463392 EXP NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11463391 EXP NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human) Bcl-2-binding component 3 isoform PUMA alpha (human)|hBBC3/iso:1 acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11463392 EXP NCBITaxon:9606 UniProtKB:Q9BXH1-1 20090918 PRO:JAN PR:Q9C658 protein decapping 5 (Arabidopsis thaliana) At-LSM14B|At1g26110|DCP5|F14G11.8|F28B23.21 enables GO:0005515 protein binding PR:000037415 PMID:22407295 IPI NCBITaxon:3702 UniProtKB:Q9C658 20140403 PRO:LVM PR:Q9C658 protein decapping 5 (Arabidopsis thaliana) At-LSM14B|At1g26110|DCP5|F14G11.8|F28B23.21 enables GO:0005515 protein binding PR:000037416 PMID:22407295 IPI NCBITaxon:3702 UniProtKB:Q9C658 20140403 PRO:LVM PR:Q9CQ18 ribonuclease H2 subunit C (mouse) Ayp1|mRNASEH2C|ribonuclease HI subunit C (mouse)|RNase H2 subunit C (mouse)|Rnaseh2c part_of GO:0032299 ribonuclease H2 complex PMID:19923215 EXP NCBITaxon:10090 UniProtKB:Q9CQ18 20111003 PRO:HJD PR:Q9CQ39-1 mediator of RNA polymerase II transcription subunit 21 isoform 1 (mouse) mMED21/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1347064 20120523 MGI:MGI PR:Q9CQA5-1 mediator of RNA polymerase II transcription subunit 4 isoform 1 (mouse) mMED4/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1914631 20120523 MGI:MGI PR:Q9CS84-1 neurexin-1-alpha isoform a1 (mouse) mNRXN1/iso:a1|neurexin-1-alpha isoform 1a located_in GO:0005886 plasma membrane MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 UniProtKB:Q63372 MGI:1096391 20131107 MGI:MGI PR:Q9CS84-1 neurexin-1-alpha isoform a1 (mouse) mNRXN1/iso:a1|neurexin-1-alpha isoform 1a acts_upstream_of_or_within GO:0006904 vesicle docking involved in exocytosis MGI_ref:2154458|GO_REF:0000008 ISO NCBITaxon:10090 UniProtKB:Q63372 MGI:1096391 20131107 MGI:MGI PR:Q9CS84-1 neurexin-1-alpha isoform a1 (mouse) mNRXN1/iso:a1|neurexin-1-alpha isoform 1a acts_upstream_of_or_within GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus MGI_ref:5315831|PMID:22235116 IMP NCBITaxon:10090 MGI_allele:3042794 MGI:1096391 20131107 MGI:MGI regulates_o_occurs_in(MA:0000127) PR:Q9CUN6 E3 ubiquitin-protein ligase SMURF1 (mouse) HECT-type E3 ubiquitin transferase SMURF1 (mouse)|mSMURF1|SMAD ubiquitination regulatory factor 1 (mouse)|SMAD-specific E3 ubiquitin-protein ligase 1 (mouse)|Smurf1 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:14711801 IDA NCBITaxon:10090 UniProtKB:Q9CUN6 20080301 PRO:CNA PR:Q9CUN6-1 E3 ubiquitin-protein ligase SMURF1 isoform Short (mouse) mSMURF1/iso:Short|Smurf1 isoform 1 (mouse) located_in GO:0005622 intracellular anatomical structure PMID:14711801 IDA NCBITaxon:10090 UniProtKB:Q9CUN6-1 20080301 PRO:CNA PR:Q9CWY8 ribonuclease H2 subunit A (mouse) mRNASEH2A|ribonuclease HI large subunit (mouse)|ribonuclease HI subunit A (mouse)|RNase H2 subunit A (mouse)|RNase HI large subunit (mouse)|Rnaseh2a|Rnasehi part_of GO:0032299 ribonuclease H2 complex PMID:19923215 EXP NCBITaxon:10090 UniProtKB:Q9CWY8 20111003 PRO:HJD PR:Q9CXU1-1 mediator of RNA polymerase II transcription subunit 31 isoform 1 (mouse) mMED31/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1914529 20120523 MGI:MGI PR:Q9CYI4-1 putative RNA-binding protein Luc7-like 1 isoform 1 (mouse) mLUC7L/iso:1 located_in GO:0005634 nucleus MGI_ref:3055693|PMID:15474286 IDA NCBITaxon:10090 MGI:1914228 20080807 MGI:MGI PR:Q9CYI4-2 putative RNA-binding protein Luc7-like 1 isoform 2 (mouse) mLUC7L/iso:2 located_in GO:0005634 nucleus MGI_ref:3055693|PMID:15474286 IDA NCBITaxon:10090 MGI:1914228 20140401 MGI:MGI PR:Q9CZ42-1 ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 1 (mouse) mNAXD/iso:1 located_in GO:0005739 mitochondrion MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:1913353 20150603 MGI:MGI PR:Q9CZ42-2 ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 2 (mouse) mNAXD/iso:2 located_in GO:0005829 cytosol MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:1913353 20150603 MGI:MGI PR:Q9CZ42-2 ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 2 (mouse) mNAXD/iso:2 NOT located_in GO:0005739 mitochondrion MGI_ref:5581381|PMID:24611804 IDA NCBITaxon:10090 MGI:1913353 20150603 MGI:MGI PR:Q9CZ82-1 mediator of RNA polymerase II transcription subunit 18 isoform 1 (mouse) mMED18/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1914469 20120523 MGI:MGI PR:Q9D666-5 SUN domain-containing protein 1 isoform m5 (mouse) mSUN1/iso:m5|SUN domain-containing protein 1 isoform eta (mouse) located_in GO:0002080 acrosomal membrane MGI_ref:4829712|PMID:20711465 IDA NCBITaxon:10090 MGI:1924303 20101123 MGI:MGI PR:Q9D6R2-1 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (mouse) mIDH3A/iso:1 located_in GO:0005739 mitochondrion MGI_ref:2682130|PMID:14651853 IDA NCBITaxon:10090 MGI:1915084 20100308 MGI:MGI part_of(MA:0000358)|part_of(MA:0000168)|part_of(MA:0000368)|part_of(MA:0000072) PR:Q9D6R2-1 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (mouse) mIDH3A/iso:1 located_in GO:0005739 mitochondrion MGI_ref:3852644|PMID:18614015 IDA NCBITaxon:10090 MGI:1915084 20100308 MGI:MGI PR:Q9D6Y7-1 mitochondrial peptide methionine sulfoxide reductase isoform 1 (mouse) mMSRA/iso:1|MSRA isoform 1 (mouse) located_in GO:0005739 mitochondrion MGI_ref:4833932|PMID:20368336 IDA NCBITaxon:10090 MGI:106916 20130612 MGI:MGI PR:Q9D6Y7-2 mitochondrial peptide methionine sulfoxide reductase isoform 2 (mouse) mMSRA/iso:2|MSRA isoform 2 (mouse) located_in GO:0005737 cytoplasm MGI_ref:4833932|PMID:20368336 IDA NCBITaxon:10090 MGI:106916 20130612 MGI:MGI PR:Q9D7W5-1 mediator of RNA polymerase II transcription subunit 8 isoform 1 (mouse) mMED8/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1915269 20120523 MGI:MGI PR:Q9D8H7-1 metalloendopeptidase OMA1, mitochondrial isoform 1 (mouse) mOMA1/iso:1 acts_upstream_of_or_within GO:0007005 mitochondrion organization MGI_ref:4421613|PMID:20038678 IDA NCBITaxon:10090 MGI:1921393 20120424 MGI:MGI occurs_in(CL:0000057) PR:Q9D8H7-1 metalloendopeptidase OMA1, mitochondrial isoform 1 (mouse) mOMA1/iso:1 acts_upstream_of_or_within GO:0008053 mitochondrial fusion MGI_ref:4421613|PMID:20038678 IDA NCBITaxon:10090 MGI:1921393 20120424 MGI:MGI occurs_in(CL:0000057) PR:Q9D9V2-1 equatorin isoform 1 (mouse) mEQTN/iso:1 located_in GO:0005886 plasma membrane MGI_ref:4397498|PMID:19605790 IDA NCBITaxon:10090 MGI:97857 MGI:1915003 20110418 MGI:MGI PR:Q9D9V2-2 equatorin isoform 2 (mouse) mEQTN/iso:2 located_in GO:0002080 acrosomal membrane MGI_ref:3653981|PMID:16831425 IDA NCBITaxon:10090 MGI:97857 MGI:1915003 20110418 MGI:MGI part_of(CL:0000018) PR:Q9DA08-1 SAGA-associated factor 29 isoform 1 (mouse) mSGF29/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1922815 20120611 MGI:MGI PR:Q9DB40-1 mediator of RNA polymerase II transcription subunit 27 isoform 1 (mouse) mMED27/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1916225 20120523 MGI:MGI PR:Q9DCB1-1 high mobility group nucleosome-binding domain-containing protein 3 isoform 1 (mouse) mHMGN3/iso:1 enables GO:0003682 chromatin binding MGI_ref:3041919|PMID:15082770 IDA NCBITaxon:10090 MGI:2138069 20101015 MGI:MGI has_participant(MGI:MGI:95760) PR:Q9DCB1-1 high mobility group nucleosome-binding domain-containing protein 3 isoform 1 (mouse) mHMGN3/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3041919|PMID:15082770 IDA NCBITaxon:10090 MGI:2138069 20101015 MGI:MGI has_regulation_target(MGI:MGI:95760) PR:Q9DCB1-2 high mobility group nucleosome-binding domain-containing protein 3 isoform 2 (mouse) mHMGN3/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3041919|PMID:15082770 IDA NCBITaxon:10090 MGI:2138069 20140327 MGI:MGI has_regulation_target(MGI:MGI:95760) PR:Q9EP65 DNA repair protein RAD51 homolog 4 isoform d4 (mouse) mRad51d/iso:d4 enables GO:0005515 protein binding PR:Q9CX47 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:Q9EP65 DNA repair protein RAD51 homolog 4 isoform d4 (mouse) mRad51d/iso:d4 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP65 DNA repair protein RAD51 homolog 4 isoform d4 (mouse) mRad51d/iso:d4 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP65 DNA repair protein RAD51 homolog 4 isoform d4 (mouse) mRad51d/iso:d4 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EP85 DNA repair protein RAD51 homolog 4 isoform d3 (mouse) mRad51d/iso:d3 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP85 DNA repair protein RAD51 homolog 4 isoform d3 (mouse) mRad51d/iso:d3 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP85 DNA repair protein RAD51 homolog 4 isoform d3 (mouse) mRad51d/iso:d3 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EP87 DNA repair protein RAD51 homolog 4 isoform d2 (mouse) mRad51d/iso:d2 enables GO:0005515 protein binding PR:Q924H5-1 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:Q9EP87 DNA repair protein RAD51 homolog 4 isoform d2 (mouse) mRad51d/iso:d2 enables GO:0005515 protein binding PR:Q9CX47 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:Q9EP87 DNA repair protein RAD51 homolog 4 isoform d2 (mouse) mRad51d/iso:d2 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP87 DNA repair protein RAD51 homolog 4 isoform d2 (mouse) mRad51d/iso:d2 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP87 DNA repair protein RAD51 homolog 4 isoform d2 (mouse) mRad51d/iso:d2 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EP92 DNA repair protein RAD51 homolog 4 isoform d7 (mouse) mRad51d/iso:d7 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP92 DNA repair protein RAD51 homolog 4 isoform d7 (mouse) mRad51d/iso:d7 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EP92 DNA repair protein RAD51 homolog 4 isoform d7 (mouse) mRad51d/iso:d7 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EPA9 DNA repair protein RAD51 homolog 4 isoform d1 (mouse) mRad51d/iso:d1 enables GO:0005515 protein binding PR:Q9CX47 MGI_ref:4430476|PMID:19327148 IPI NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI PR:Q9EPA9 DNA repair protein RAD51 homolog 4 isoform d1 (mouse) mRad51d/iso:d1 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EPA9 DNA repair protein RAD51 homolog 4 isoform d1 (mouse) mRad51d/iso:d1 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EPA9 DNA repair protein RAD51 homolog 4 isoform d1 (mouse) mRad51d/iso:d1 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EPC0 DNA repair protein RAD51 homolog 4 isoform d6 (mouse) mRad51d/iso:d6 located_in GO:0005634 nucleus MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EPC0 DNA repair protein RAD51 homolog 4 isoform d6 (mouse) mRad51d/iso:d6 located_in GO:0005737 cytoplasm MGI_ref:4430476|PMID:19327148 IDA NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI part_of(CL:0000057) PR:Q9EPC0 DNA repair protein RAD51 homolog 4 isoform d6 (mouse) mRad51d/iso:d6 NOT acts_upstream_of_or_within GO:0006289 nucleotide-excision repair MGI_ref:4430476|PMID:19327148 IMP NCBITaxon:10090 MGI:1261809 20141211 MGI:MGI occurs_in(CL:0000057) PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac enables GO:0005034 osmosensor activity PMID:11025659 IMP NCBITaxon:10090 MGI_allele:2667379 UniProtKB:Q9EPK8 20080923 mgi:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0030103 vasopressin secretion PMID:12777254 IMP NCBITaxon:10090 MGI_allele:2667379 UniProtKB:Q9EPK8 20080923 mgi:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0042538 hyperosmotic salinity response PMID:12777254 IMP NCBITaxon:10090 MGI_allele:2667379 UniProtKB:Q9EPK8 20080923 mgi:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0047484 regulation of response to osmotic stress PMID:12777254 IMP NCBITaxon:10090 MGI_allele:2667379 UniProtKB:Q9EPK8 20080923 mgi:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) enables GO:0005515 protein binding PR:O88735 PMID:14517216 IPI NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 mgi:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) located_in GO:0005886 plasma membrane PMID:14517216 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 mgi:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) acts_upstream_of_or_within GO:0006970 response to osmotic stress PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 mgi:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) acts_upstream_of_or_within GO:0007231 osmosensory signaling pathway PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 mgi:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) contributes_to enables GO:0005262 calcium channel activity PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 mgi:HJD PR:Q9EPQ8-1 transcription factor 20 isoform 1 (mouse) mTCF20/iso:1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:7760812 EXP NCBITaxon:10090 UniProtKB:Q9EPQ8-1 20091112 PRO:HJD PR:Q9EPQ8-1 transcription factor 20 isoform 1 (mouse) mTCF20/iso:1 located_in GO:0005634 nucleus PMID:7760812 EXP NCBITaxon:10090 UniProtKB:Q9EPQ8-1 20091112 PRO:HJD PR:Q9EPQ8-1 transcription factor 20 isoform 1 (mouse) mTCF20/iso:1 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II PMID:7760812 EXP NCBITaxon:10090 UniProtKB:Q9EPQ8-1 20091112 PRO:HJD PR:Q9EPQ8-2 transcription factor 20 isoform 2 (mouse) mTCF20/iso:2 enables GO:0005515 protein binding PR:Q9QZS2 MGI_ref:1888582|PMID:10849425 IPI NCBITaxon:10090 MGI:108399 20091112 MGI:MGI PR:Q9EPQ8-2 transcription factor 20 isoform 2 (mouse) mTCF20/iso:2 enables GO:0005515 protein binding PR:Q9QZS2 MGI_ref:1888582|PMID:10849425 IPI NCBITaxon:10090 UniProtKB:Q9EPQ8-2 20091120 PRO:HJD PR:Q9EPQ8-2 transcription factor 20 isoform 2 (mouse) mTCF20/iso:2 located_in GO:0005634 nucleus MGI_ref:1888582|PMID:10849425 IDA NCBITaxon:10090 MGI:108399 20100602 MGI:MGI PR:Q9EPQ8-2 transcription factor 20 isoform 2 (mouse) mTCF20/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1888582|PMID:10849425 IDA NCBITaxon:10090 MGI:108399 20091112 MGI:MGI PR:Q9EPQ8-2 transcription factor 20 isoform 2 (mouse) mTCF20/iso:2 acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1928403|PMID:10995766 IDA NCBITaxon:10090 MGI:108399 20091112 MGI:MGI PR:Q9EQR3-1 small conductance calcium-activated potassium channel protein 1 isoform 1 (mouse) mKCNN1/iso:1 enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-1 20080601 PRO:CNA PR:Q9EQR3-3 small conductance calcium-activated potassium channel protein 1 isoform V (mouse) Kcnn1 isoform 3 (mouse)|mKCNN1/iso:V|small conductance calcium-activated potassium channel protein 1 isoform 3 (mouse) NOT enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-3 20080601 PRO:CNA PR:Q9EQR3-4 small conductance calcium-activated potassium channel protein 1 isoform VI (mouse) Kcnn1 isoform 4 (mouse)|mKCNN1/iso:VI|small conductance calcium-activated potassium channel protein 1 isoform 4 (mouse) NOT enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-4 20080601 PRO:CNA PR:Q9EQR3-5 small conductance calcium-activated potassium channel protein 1 isoform VII (mouse) Kcnn1 isoform 5 (mouse)|mKCNN1/iso:VII|small conductance calcium-activated potassium channel protein 1 isoform 5 (mouse) NOT enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-5 20080601 PRO:CNA PR:Q9EQR3-6 small conductance calcium-activated potassium channel protein 1 isoform VIII (mouse) Kcnn1 isoform 6 (mouse)|mKCNN1/iso:VIII|small conductance calcium-activated potassium channel protein 1 isoform 6 (mouse) NOT enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-6 20080601 PRO:CNA PR:Q9EQR3-7 small conductance calcium-activated potassium channel protein 1 isoform IV (mouse) Kcnn1 isoform 7 (mouse)|mKCNN1/iso:IV|small conductance calcium-activated potassium channel protein 1 isoform 7 (mouse) decreased enables GO:0005516 calmodulin binding PR:000002605 PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-7 20080601 PRO:CNA PR:Q9EQR3-8 small conductance calcium-activated potassium channel protein 1 isoform III (mouse) Kcnn1 isoform 8 (mouse)|mKCNN1/iso:III|small conductance calcium-activated potassium channel protein 1 isoform 8 (mouse) decreased enables GO:0005516 calmodulin binding PR:000002605 PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-8 20080601 PRO:CNA PR:Q9EQR3-9 small conductance calcium-activated potassium channel protein 1 isoform II (mouse) Kcnn1 isoform 9 (mouse)|mKCNN1/iso:II|small conductance calcium-activated potassium channel protein 1 isoform 9 (mouse) enables GO:0005516 calmodulin binding PMID:11267657 IDA NCBITaxon:10090 UniProtKB:Q9EQR3-9 20080601 PRO:CNA PR:Q9EQZ7-1 regulating synaptic membrane exocytosis protein 2 isoform 1 (mouse) mRIMS2/iso:1|RIM2-alpha (mouse) acts_upstream_of_or_within GO:0030073 insulin secretion MGI_ref:4821020|PMID:20674857 IMP NCBITaxon:10090 MGI_allele:4838195 MGI:2152972 20130111 MGI:MGI PR:Q9ERM2-1 intercellular adhesion molecule 4 isoform 1 (mouse) mICAM4/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3573745|PMID:12406883 IDA NCBITaxon:10090 MGI:1925619 20140226 MGI:MGI PR:Q9ERM2-1 intercellular adhesion molecule 4 isoform 1 (mouse) mICAM4/iso:1 located_in GO:0005886 plasma membrane MGI_ref:3573745|PMID:12406883 IDA NCBITaxon:10090 MGI:1925619 20140226 MGI:MGI PR:Q9ERM2-2 intercellular adhesion molecule 4 isoform 2 (mouse) ICAM-4S (mouse)|mICAM4/iso:2 located_in GO:0005615 extracellular space MGI_ref:3573745|PMID:12406883 IDA NCBITaxon:10090 MGI:1925619 20140226 MGI:MGI PR:Q9ERM2-2 intercellular adhesion molecule 4 isoform 2 (mouse) ICAM-4S (mouse)|mICAM4/iso:2 located_in GO:0005737 cytoplasm MGI_ref:3573745|PMID:12406883 IDA NCBITaxon:10090 MGI:1925619 20140226 MGI:MGI PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse) mINPP5D/iso:2 enables GO:0004445 inositol-polyphosphate 5-phosphatase activity MGI_ref:85578|PMID:8643691 IDA NCBITaxon:10090 MGI:107357 20090909 MGI:MGI PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse) mINPP5D/iso:2 enables GO:0017124 SH3 domain binding MGI_ref:85578|PMID:8643691 IDA NCBITaxon:10090 MGI:107357 20090909 MGI:MGI PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse) mINPP5D/iso:2 enables GO:0034594 phosphatidylinositol trisphosphate phosphatase activity MGI_ref:85574|PMID:8890215 IDA NCBITaxon:10090 MGI:107357 20090908 MGI:MGI PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse) mINPP5D/iso:2 enables GO:0051425 PTB domain binding MGI_ref:85577|PMID:8654924 IDA NCBITaxon:10090 MGI:107357 20090908 MGI:MGI PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse) mINPP5D/iso:2 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation MGI_ref:85574|PMID:8890215 IDA NCBITaxon:10090 MGI:107357 20090908 MGI:MGI PR:Q9ES64-3 harmonin isoform 1 (mouse) harmonin isoform a1 (mouse)|mUsh1c/iso:1 enables GO:0005515 protein binding PR:E9Q9W7 MGI_ref:3831621|PMID:19028668 IPI NCBITaxon:10090 MGI:1919338 20150309 MGI:MGI occurs_in(MA:0000276) PR:Q9ESZ8-1 general transcription factor II-I isoform 1 (mouse) GTF2i Gamma|mGTF2I/iso:1 located_in GO:0005634 nucleus MGI_ref:3044088|PMID:14751286 IDA NCBITaxon:10090 MGI:1202722 20090625 MGI:MGI part_of(MA:0000956),part_of(CL:0000598) PR:Q9ESZ8-1 general transcription factor II-I isoform 1 (mouse) GTF2i Gamma|mGTF2I/iso:1 located_in GO:0042995 cell projection MGI_ref:3044088|PMID:14751286 IDA NCBITaxon:10090 MGI:1202722 20090625 MGI:MGI part_of(MA:0000956),part_of(CL:0000598) PR:Q9ESZ8-1 general transcription factor II-I isoform 1 (mouse) GTF2i Gamma|mGTF2I/iso:1 located_in GO:0043025 neuronal cell body MGI_ref:3044088|PMID:14751286 IDA NCBITaxon:10090 MGI:1202722 20090413 MGI:MGI part_of(MA:0000956),part_of(CL:0000598) PR:Q9ESZ8-2 general transcription factor II-I isoform 2 (mouse) GTF2i Beta|GTF2i Long|mGTF2I/iso:2 located_in GO:0005634 nucleus MGI_ref:3688993|PMID:17052463 IDA NCBITaxon:10090 MGI:1202722 20090414 MGI:MGI PR:Q9ESZ8-2 general transcription factor II-I isoform 2 (mouse) GTF2i Beta|GTF2i Long|mGTF2I/iso:2 acts_upstream_of_or_within GO:0014886 transition between slow and fast fiber MGI_ref:5504578|PMID:22899722 IDA NCBITaxon:10090 MGI:1202722 20140303 MGI:MGI PR:Q9ESZ8-4 general transcription factor II-I isoform 4 (mouse) GTF2i Delta|GTF2i Short|mGTF2I/iso:4 enables GO:0051019 mitogen-activated protein kinase binding MGI_ref:3688993|PMID:17052463 IDA NCBITaxon:10090 MGI:1202722 20090413 MGI:MGI PR:Q9H2S1-1 small conductance calcium-activated potassium channel protein 2 isoform 1 (human) hKCNN2/iso:1 located_in GO:0009986 cell surface PMID:11395478 IDA NCBITaxon:9606 UniProtKB:Q9H2S1-1 20080601 PRO:CNA PR:Q9H2X0-1 chordin isoform 1 (human) hCHRD/iso:1 acts_upstream_of_or_within GO:0001501 skeletal system development PMID:9782094 EXP NCBITaxon:9606 UniProtKB:Q9H2X0-1 20080301 PRO:CNA PR:Q9H2X0-2 chordin isoform 2 (human) hCHRD/iso:2 NOT acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:11472837 EXP NCBITaxon:9606 UniProtKB:Q9H2X0-2 20080301 PRO:CNA PR:Q9H2X0-4 chordin isoform 4 (human) hCHRD/iso:4 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:11472837 IDA NCBITaxon:9606 UniProtKB:Q9H2X0-4 20080301 PRO:CNA PR:Q9H2X0-5 chordin isoform 5 (human) hCHRD/iso:5 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:11472837 IDA NCBITaxon:9606 UniProtKB:Q9H2X0-5 20080301 PRO:CNA PR:Q9H4B4 serine/threonine-protein kinase PLK3 (human) CNK|cytokine-inducible serine/threonine-protein kinase (human)|FGF-inducible kinase (human)|FNK|hPLK3|PLK-3 (human)|PLK3|Polo-like kinase 3 (human)|PRK|proliferation-related kinase (human) enables GO:0005515 protein binding PR:O14965 PMID:15190214 IPI NCBITaxon:9606 UniProtKB:Q9H4B4 20121112 PRO:KER Timing=interphase and mitosis. PR:Q9H4B4 serine/threonine-protein kinase PLK3 (human) CNK|cytokine-inducible serine/threonine-protein kinase (human)|FGF-inducible kinase (human)|FNK|hPLK3|PLK-3 (human)|PLK3|Polo-like kinase 3 (human)|PRK|proliferation-related kinase (human) enables GO:0005515 protein binding PR:O60566 PMID:15190214 IPI NCBITaxon:9606 UniProtKB:Q9H4B4 20121112 PRO:KER Timing=spindle depolymerization (nocodazole). PR:Q9H4B4 serine/threonine-protein kinase PLK3 (human) CNK|cytokine-inducible serine/threonine-protein kinase (human)|FGF-inducible kinase (human)|FNK|hPLK3|PLK-3 (human)|PLK3|Polo-like kinase 3 (human)|PRK|proliferation-related kinase (human) located_in GO:0000922 spindle pole PMID:15190214 EXP NCBITaxon:9606 UniProtKB:Q9H4B4 20121112 PRO:KER Timing=Mitosis. PR:Q9H4B4 serine/threonine-protein kinase PLK3 (human) CNK|cytokine-inducible serine/threonine-protein kinase (human)|FGF-inducible kinase (human)|FNK|hPLK3|PLK-3 (human)|PLK3|Polo-like kinase 3 (human)|PRK|proliferation-related kinase (human) located_in GO:0005813 centrosome PMID:15190214 EXP NCBITaxon:9606 UniProtKB:Q9H4B4 20121112 PRO:KER Timing=interphase. PR:Q9H4B4 serine/threonine-protein kinase PLK3 (human) CNK|cytokine-inducible serine/threonine-protein kinase (human)|FGF-inducible kinase (human)|FNK|hPLK3|PLK-3 (human)|PLK3|Polo-like kinase 3 (human)|PRK|proliferation-related kinase (human) located_in GO:0030496 midbody PMID:15190214 EXP NCBITaxon:9606 UniProtKB:Q9H4B4 20121112 PRO:KER Timing=Mitosis. PR:Q9HAU4 E3 ubiquitin-protein ligase SMURF2 (human) HECT-type E3 ubiquitin transferase SMURF2 (human)|hSMURF2|SMAD ubiquitination regulatory factor 2 (human)|SMAD-specific E3 ubiquitin-protein ligase 2 (human)|SMURF2 enables GO:0004842 ubiquitin-protein transferase activity PMID:14755250 IDA NCBITaxon:9606 UniProtKB:Q9HAU4 20080301 PRO:CNA PR:Q9HAU4 E3 ubiquitin-protein ligase SMURF2 (human) HECT-type E3 ubiquitin transferase SMURF2 (human)|hSMURF2|SMAD ubiquitination regulatory factor 2 (human)|SMAD-specific E3 ubiquitin-protein ligase 2 (human)|SMURF2 enables GO:0005515 protein binding PR:Q9Y3C5 PMID:14755250 IPI NCBITaxon:9606 UniProtKB:Q9HAU4 20080301 PRO:CNA PR:Q9HAU4 E3 ubiquitin-protein ligase SMURF2 (human) HECT-type E3 ubiquitin transferase SMURF2 (human)|hSMURF2|SMAD ubiquitination regulatory factor 2 (human)|SMAD-specific E3 ubiquitin-protein ligase 2 (human)|SMURF2 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:14755250 IDA NCBITaxon:9606 UniProtKB:Q9HAU4 20080301 PRO:CNA PR:Q9HAU4 E3 ubiquitin-protein ligase SMURF2 (human) HECT-type E3 ubiquitin transferase SMURF2 (human)|hSMURF2|SMAD ubiquitination regulatory factor 2 (human)|SMAD-specific E3 ubiquitin-protein ligase 2 (human)|SMURF2 acts_upstream_of_or_within GO:0017015 regulation of transforming growth factor beta receptor signaling pathway PMID:11016919|PMID:11158580|PMID:11163210|PMID:15862290 IDA NCBITaxon:9606 UniProtKB:Q9HAU4 20080301 PRO:CNA PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human) hTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (human)|TRPV4 isoform 1 (human) enables GO:0042802 identical protein binding PR:Q9HBA0-1 PMID:16293632 IPI NCBITaxon:9606 UniProtKB:Q9HBA0-1 20081015 PRO:CNA PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human) hTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (human)|TRPV4 isoform 1 (human) located_in GO:0005886 plasma membrane PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-1 20081015 PRO:CNA PR:Q9HBA0-2 transient receptor potential cation channel subfamily V member 4 isoform B (human) hTRPV4/iso:2|hTRPV4/iso:B|transient receptor potential cation channel subfamily V member 4 isoform 2 (human)|transient receptor potential cation channel subfamily V member 4 isoform OTRPC4beta (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-2 20081015 PRO:CNA PR:Q9HBA0-4 transient receptor potential cation channel subfamily V member 4 isoform C (human) hTRPV4/iso:4|hTRPV4/iso:C|transient receptor potential cation channel subfamily V member 4 isoform 4 (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-4 20081015 PRO:CNA PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human) hTRPV4/iso:5|hTRPV4/iso:D|transient receptor potential cation channel subfamily V member 4 isoform 5 (human) enables GO:0042802 identical protein binding PR:Q9HBA0-5 PMID:16293632 IPI NCBITaxon:9606 UniProtKB:Q9HBA0-5 20081015 PRO:CNA PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human) hTRPV4/iso:5|hTRPV4/iso:D|transient receptor potential cation channel subfamily V member 4 isoform 5 (human) located_in GO:0005886 plasma membrane PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-5 20081015 PRO:CNA PR:Q9HBA0-6 transient receptor potential cation channel subfamily V member 4 isoform E (human) hTRPV4/iso:6|hTRPV4/iso:E|transient receptor potential cation channel subfamily V member 4 isoform 6 (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-6 20081015 PRO:CNA PR:Q9HCE7 E3 ubiquitin-protein ligase SMURF1 (human) HECT-type E3 ubiquitin transferase SMURF1 (human)|hSMURF1|KIAA1625|SMAD ubiquitination regulatory factor 1 (human)|SMAD-specific E3 ubiquitin-protein ligase 1 (human)|SMURF1 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:10458166 IDA NCBITaxon:9606 UniProtKB:Q9HCE7 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short enables GO:0004842 ubiquitin-protein transferase activity PMID:10458166 IDA NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short enables GO:0005515 protein binding PMID:11278251|PMID:16299379 IPI NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short located_in GO:0005622 intracellular anatomical structure PMID:10458166 IDA NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short acts_upstream_of_or_within GO:0036211 protein modification process PMID:10458166 IDA NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10458166 IDA NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCE7-2 E3 ubiquitin-protein ligase SMURF1 isoform Short (human) hSMURF1/iso:Short acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:12857866 IDA NCBITaxon:9606 UniProtKB:Q9HCE7-2 20080301 PRO:CNA PR:Q9HCX4 short transient receptor potential channel 7 (human) hTRP7|hTRPC7|transient receptor protein 7 (human)|TRP-7 (human)|TRP7|TRPC7|TrpC7 (human) enables GO:0005515 protein binding PR:P20591 PMID:15757897 IPI NCBITaxon:9606 UniProtKB:Q9HCX4 20081015 PRO:CNA PR:Q9JHD1-1 histone acetyltransferase KAT2B isoform 1 (mouse) mKAT2B/iso:1 part_of GO:0140672 ATAC complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1343094 20120611 MGI:MGI PR:Q9JHF9 lymphocyte antigen 96 (mouse) ESOP-1 (mouse)|Esop1|Ly-96 (mouse)|Ly96|Md2|mLY96|protein MD-2 (mouse) enables GO:0005515 protein binding PR:O35716 PMID:19296467 IPI NCBITaxon:10090 UniProtKB:Q9JHF9 20140514 PRO:CNA PR:Q9JIW5-1 mothers against decapentaplegic homolog 9 isoform 1 (mouse) mSMAD9/iso:1 located_in GO:0005622 intracellular anatomical structure PMID:10814522 IDA NCBITaxon:10090 UniProtKB:Q9JIW5-1 20080301 PRO:CNA PR:Q9JIW5-1 mothers against decapentaplegic homolog 9 isoform 1 (mouse) mSMAD9/iso:1 acts_upstream_of_or_within GO:0048856 anatomical structure development PMID:15899870 IDA NCBITaxon:10090 UniProtKB:Q9JIW5-1 20080301 PRO:CNA PR:Q9JJV2-1 profilin-2 isoform 1 (mouse) mPFN2/iso:1|profilin-2 isoform IIa (mouse) located_in GO:0043195 terminal bouton MGI_ref:3714870|PMID:17541406 IDA NCBITaxon:10090 MGI:97550 20110103 MGI:MGI part_of(MA:0000168) PR:Q9JJV2-1 profilin-2 isoform 1 (mouse) mPFN2/iso:1|profilin-2 isoform IIa (mouse) acts_upstream_of_or_within GO:0030837 negative regulation of actin filament polymerization MGI_ref:4844066|PMID:18001770 IDA NCBITaxon:10090 MGI:97550 20110103 MGI:MGI PR:Q9JJV9-1 sodium channel protein type 5 subunit alpha isoform 1 (mouse) mScn5a/iso:1 acts_upstream_of_or_within GO:0006814 sodium ion transport MGI_ref:3623302|PMID:11834499 IDA NCBITaxon:10090 MGI:98251 20110127 MGI:MGI PR:Q9JJZ8-1 cyclic nucleotide-gated cation channel alpha-3 isoform m1 (mouse) Cnga3 isoform 1 (mouse)|mCNGA3/iso:m1 located_in GO:0001750 photoreceptor outer segment PMID:10813773|PMID:15634774 IDA NCBITaxon:10090 UniProtKB:Q9JJZ8-1 20080601 PRO:CNA PR:Q9JJZ8-1 cyclic nucleotide-gated cation channel alpha-3 isoform m1 (mouse) Cnga3 isoform 1 (mouse)|mCNGA3/iso:m1 part_of GO:0032991 protein-containing complex PMID:10662822 IDA NCBITaxon:10090 UniProtKB:Q9JJZ8-1 20080601 PRO:CNA PR:Q9JJZ8-1 cyclic nucleotide-gated cation channel alpha-3 isoform m1 (mouse) Cnga3 isoform 1 (mouse)|mCNGA3/iso:m1 contributes_to enables GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity PMID:10662822 IDA NCBITaxon:10090 UniProtKB:Q9JJZ8-1 20080601 PRO:CNA PR:Q9JJZ9-1 cyclic nucleotide-gated cation channel beta-3 isoform 1 (mouse) mCNGB3/iso:1 enables GO:0005223 intracellularly cGMP-activated cation channel activity PMID:10662822 IDA NCBITaxon:10090 UniProtKB:Q9JJZ9-1 20080601 PRO:CNA PR:Q9JJZ9-1 cyclic nucleotide-gated cation channel beta-3 isoform 1 (mouse) mCNGB3/iso:1 enables GO:0005515 protein binding PMID:10662822 IPI NCBITaxon:10090 UniProtKB:Q9JJZ9-1 20080601 PRO:CNA PR:Q9JJZ9-1 cyclic nucleotide-gated cation channel beta-3 isoform 1 (mouse) mCNGB3/iso:1 located_in GO:0001750 photoreceptor outer segment PMID:15634774 IDA NCBITaxon:10090 UniProtKB:Q9JJZ9-1 20080601 PRO:CNA PR:Q9JJZ9-1 cyclic nucleotide-gated cation channel beta-3 isoform 1 (mouse) mCNGB3/iso:1 located_in GO:0005886 plasma membrane PMID:10662822 IDA NCBITaxon:10090 UniProtKB:Q9JJZ9-1 20080601 PRO:CNA PR:Q9JK45-1 potassium voltage-gated channel subfamily KQT member 5 isoform 1 (mouse) mKCNQ5/iso:1 enables GO:0005249 voltage-gated potassium channel activity PMID:15963599 IDA NCBITaxon:10090 UniProtKB:Q9JK45-1 20080601 PRO:CNA PR:Q9JK45-1 potassium voltage-gated channel subfamily KQT member 5 isoform 1 (mouse) mKCNQ5/iso:1 acts_upstream_of_or_within GO:0006813 potassium ion transport PMID:15963599 IDA NCBITaxon:10090 UniProtKB:Q9JK45-1 20080601 PRO:CNA PR:Q9JK97 potassium voltage-gated channel subfamily KQT member 4 (mouse) Kcnq4|KQT-like 4 (mouse)|mKCNQ4|potassium channel subunit alpha KvLQT4 (mouse)|voltage-gated potassium channel subunit Kv7.4 (mouse) acts_upstream_of_or_within GO:0007605 sensory perception of sound PMID:16437162 IDA NCBITaxon:10090 UniProtKB:Q9JK97 20080601 PRO:CNA PR:Q9JK97 potassium voltage-gated channel subfamily KQT member 4 (mouse) Kcnq4|KQT-like 4 (mouse)|mKCNQ4|potassium channel subunit alpha KvLQT4 (mouse)|voltage-gated potassium channel subunit Kv7.4 (mouse) acts_upstream_of_or_within GO:0042472 inner ear morphogenesis PMID:16437162 IDA NCBITaxon:10090 UniProtKB:Q9JK97 20080601 PRO:CNA PR:Q9JKB3 Y-box-binding protein 3 (mouse) cold shock domain-containing protein A (mouse)|Csda|DNA-binding protein A (mouse)|Msy4|mYBX3|Y-box protein 3 (mouse)|Ybx3 acts_upstream_of_or_within GO:0001701 in utero embryonic development PMID:16954378 IMP NCBITaxon:10090 MGI:99146 UniProtKB:Q9JKB3 20090918 PRO:HJD PR:Q9JKB3 Y-box-binding protein 3 (mouse) cold shock domain-containing protein A (mouse)|Csda|DNA-binding protein A (mouse)|Msy4|mYBX3|Y-box protein 3 (mouse)|Ybx3 acts_upstream_of_or_within GO:0007283 spermatogenesis PMID:16954378 IMP NCBITaxon:10090 MGI_allele:3693011 UniProtKB:Q9JKB3 20090918 PRO:HJD PR:Q9JKB3 Y-box-binding protein 3 (mouse) cold shock domain-containing protein A (mouse)|Csda|DNA-binding protein A (mouse)|Msy4|mYBX3|Y-box protein 3 (mouse)|Ybx3 acts_upstream_of_or_within GO:0009566 fertilization PMID:16954378 IMP NCBITaxon:10090 MGI_allele:3693011 UniProtKB:Q9JKB3 20090918 PRO:HJD PR:Q9JKB3 Y-box-binding protein 3 (mouse) cold shock domain-containing protein A (mouse)|Csda|DNA-binding protein A (mouse)|Msy4|mYBX3|Y-box protein 3 (mouse)|Ybx3 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:16954378 IMP NCBITaxon:10090 MGI_allele:3693011 UniProtKB:Q9JKB3 20090918 PRO:HJD PR:Q9JKB3 Y-box-binding protein 3 (mouse) cold shock domain-containing protein A (mouse)|Csda|DNA-binding protein A (mouse)|Msy4|mYBX3|Y-box protein 3 (mouse)|Ybx3 acts_upstream_of_or_within GO:0046622 positive regulation of organ growth PMID:16954378 IMP NCBITaxon:10090 MGI_allele:3693011 UniProtKB:Q9JKB3 20090918 PRO:HJD PR:Q9JKB3-1 Y-box-binding protein 3 isoform 1 (mouse) Msy3|mYBX3/iso:1|Y-box protein 3 isoform 1 (mouse) enables GO:0003697 single-stranded DNA binding MGI_ref:3808638|PMID:18676817 IDA NCBITaxon:10090 MGI:2137670 20090723 MGI:MGI PR:Q9JKB3-2 Y-box-binding protein 3 isoform 2 (mouse) Msy3s|mYBX3/iso:2|Ybx3 isoform 2 (mouse) enables GO:0003697 single-stranded DNA binding MGI_ref:3808638|PMID:18676817 IDA NCBITaxon:10090 MGI:2137670 20111216 MGI:MGI PR:Q9JKS4-1 LIM domain-binding protein 3 isoform 1 (mouse) Cypher1c (mouse)|mLDB3/iso:1|Oracle 1 (mouse) enables GO:0051371 muscle alpha-actinin binding PR:Q9JI91 MGI_ref:1340723|PMID:10391924 IPI NCBITaxon:10090 MGI:1344412 20130307 MGI:MGI PR:Q9JKS4-6 LIM domain-binding protein 3 isoform 6 (mouse) Cypher2s (mouse)|mLDB3/iso:6 enables GO:0051371 muscle alpha-actinin binding PR:Q9JI91 MGI_ref:1340723|PMID:10391924 IPI NCBITaxon:10090 MGI:1344412 20130307 MGI:MGI PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 enables GO:0004672 protein kinase activity PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM occurs_in(GO:0009651) PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 enables GO:0004672 protein kinase activity PMID:21685179 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:CNA Target=PR:Q8LAS7. Evidence=ECO:0000181. PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 enables GO:0005515 protein binding PR:O64903 PMID:17785451 IPI NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 enables GO:0005515 protein binding PR:P25819 PMID:17785451 IPI NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 enables GO:0005515 protein binding PR:Q42547 PMID:17785451 IPI NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 located_in GO:0005886 plasma membrane PMID:12070350 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 acts_upstream_of_or_within GO:0009651 response to salt stress PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:19529820 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM occurs_in(GO:0009651) PR:Q9LDI3 CBL-interacting serine/threonine-protein kinase 24 (Arabidopsis thaliana) At-CIPK24|At5g35410|CIPK24|F6I13.1|K21B8.3|protein SALT OVERLY SENSITIVE 2 (Arabidopsis thaliana)|SNF1-related kinase 3.11 (Arabidopsis thaliana)|SnRK3.11|SOS2 acts_upstream_of_or_within GO:0071588 hydrogen peroxide mediated signaling pathway PMID:17785451 EXP NCBITaxon:3702 UniProtKB:Q9LDI3 20140415 PRO:LVM PR:Q9LN63 protein BRASSINAZOLE-RESISTANT 2 (Arabidopsis thaliana) At-BZR2|At1g19350|BES1|BIS1|BZR2|F18O14_4|protein 107 (Arabidopsis thaliana)|protein BIN2 SUBSTRATE 1 (Arabidopsis thaliana)|protein BRI1-EMS-SUPPRESSOR 1 (Arabidopsis thaliana) located_in GO:0005634 nucleus PMID:20387034 EXP NCBITaxon:3702 UniProtKB:Q9LN63 20130430 PRO:LVM PR:Q9LN63 protein BRASSINAZOLE-RESISTANT 2 (Arabidopsis thaliana) At-BZR2|At1g19350|BES1|BIS1|BZR2|F18O14_4|protein 107 (Arabidopsis thaliana)|protein BIN2 SUBSTRATE 1 (Arabidopsis thaliana)|protein BRI1-EMS-SUPPRESSOR 1 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0009742 brassinosteroid mediated signaling pathway PMID:20387034 EXP NCBITaxon:3702 UniProtKB:Q9LN63 20130430 PRO:LVM PR:Q9NNX6 CD209 antigen (human) C-type lectin domain family 4 member L (human)|CD209|CLEC4L|DC-SIGN (human)|DC-SIGN1 (human)|dendritic cell-specific ICAM-3-grabbing non-integrin 1 (human)|hCD209 enables GO:0005515 protein binding PR:000044791 PMID:12438611|PMID:15043214 IPI NCBITaxon:9606 UniProtKB:Q9NNX6 20090918 PRO:CL Note=DC-SIGN seems critical for whether HIV is bound and targeted to the endolysosomal pathway; binding between proteins from heterogeneous species PR:Q9NNX6 CD209 antigen (human) C-type lectin domain family 4 member L (human)|CD209|CLEC4L|DC-SIGN (human)|DC-SIGN1 (human)|dendritic cell-specific ICAM-3-grabbing non-integrin 1 (human)|hCD209 enables GO:0042802 identical protein binding PMID:15385553 EXP NCBITaxon:9606 UniProtKB:Q9NNX6 20090918 PRO:CL PR:Q9NNX6 CD209 antigen (human) C-type lectin domain family 4 member L (human)|CD209|CLEC4L|DC-SIGN (human)|DC-SIGN1 (human)|dendritic cell-specific ICAM-3-grabbing non-integrin 1 (human)|hCD209 located_in GO:0009986 cell surface PMID:15385553 EXP NCBITaxon:9606 UniProtKB:Q9NNX6 20090918 PRO:CL PR:Q9NNX6 CD209 antigen (human) C-type lectin domain family 4 member L (human)|CD209|CLEC4L|DC-SIGN (human)|DC-SIGN1 (human)|dendritic cell-specific ICAM-3-grabbing non-integrin 1 (human)|hCD209 NOT enables GO:0042609 CD4 receptor binding PMID:15385553 EXP NCBITaxon:9606 UniProtKB:Q9NNX6 20090918 PRO:CL PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:O15392 BioGRID:BG-592275|MINT:MINT-4509563 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:P06493 IntAct:EBI-1397779 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:Q53HL2 BioGRID:BG-463513|IntAct:EBI-1555222 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:Q5FBB7 BioGRID:BG-300524 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:Q71DI3 BioGRID:BG-725716 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP enables GO:0005515 protein binding PR:Q96GD4 BioGRID:BG-251075|IntAct:EBI-1555366|MINT:MINT-77928 IPI NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER Timing=mitosis. PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP located_in GO:0000939 inner kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:16760428 EXP NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER Target=PR:O43683. PR:Q9NQS7 inner centromere protein (human) hINCENP|INCENP acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17617734 EXP NCBITaxon:9606 UniProtKB:Q9NQS7 20130102 PRO:KER Target=PR:Q5FBB7. PR:Q9NR28-1 diablo IAP-binding mitochondrial protein isoform 1 (human) hDIABLO/iso:1 enables GO:0005515 protein binding PR:O15392 PMID:12660240 IPI NCBITaxon:9606 UniProtKB:Q9NR28-1 20090918 PRO:JAN PR:Q9NR28-1 diablo IAP-binding mitochondrial protein isoform 1 (human) hDIABLO/iso:1 enables GO:0005515 protein binding PR:P98170 PMID:12660240 IPI NCBITaxon:9606 UniProtKB:Q9NR28-1 20090918 PRO:JAN PR:Q9NR28-1 diablo IAP-binding mitochondrial protein isoform 1 (human) hDIABLO/iso:1 located_in GO:0005829 cytosol PMID:12660240 EXP NCBITaxon:9606 UniProtKB:Q9NR28-1 20090918 PRO:JAN PR:Q9NR28-1 diablo IAP-binding mitochondrial protein isoform 1 (human) hDIABLO/iso:1 acts_upstream_of_or_within GO:0000209 protein polyubiquitination PMID:14960576 EXP NCBITaxon:9606 UniProtKB:Q9NR28-1 20090918 PRO:JAN PR:Q9NR28-1 diablo IAP-binding mitochondrial protein isoform 1 (human) hDIABLO/iso:1 acts_upstream_of_or_within GO:0012501 programmed cell death PMID:12660240 EXP NCBITaxon:9606 UniProtKB:Q9NR28-1 20090918 PRO:JAN PR:Q9NR82-1 potassium voltage-gated channel subfamily KQT member 5 isoform 1 (human) hKCNQ5/iso:1 part_of GO:0008076 voltage-gated potassium channel complex PMID:10787416 IDA NCBITaxon:9606 UniProtKB:Q9NR82-1 20080601 PRO:CNA PR:Q9NR82-1 potassium voltage-gated channel subfamily KQT member 5 isoform 1 (human) hKCNQ5/iso:1 acts_upstream_of_or_within GO:0007268 chemical synaptic transmission PMID:10787416 IDA NCBITaxon:9606 UniProtKB:Q9NR82-1 20080601 PRO:CNA PR:Q9NR82-2 potassium voltage-gated channel subfamily KQT member 5 isoform 2 (human) hKCNQ5/iso:2 enables GO:0005249 voltage-gated potassium channel activity PMID:10816588 IDA NCBITaxon:9606 UniProtKB:Q9NR82-2 20080601 PRO:CNA PR:Q9NR82-3 potassium voltage-gated channel subfamily KQT member 5 isoform 3 (human) hKCNQ5/iso:3 enables GO:0005249 voltage-gated potassium channel activity PMID:10816588 IDA NCBITaxon:9606 UniProtKB:Q9NR82-3 20080601 PRO:CNA PR:Q9NZC7-1 WW domain-containing oxidoreductase isoform 1 (human) hWWOX/iso:1|WW domain-containing oxidoreductase isoform FOR II (human)|WW domain-containing oxidoreductase isoform FOR2 (human)|WW domain-containing oxidoreductase isoform WWOX v8 (human)|WW domain-containing oxidoreductase isoform WWOXv1 (human) enables GO:0005515 protein binding PR:000036589 PMID:16438931 IPI NCBITaxon:9606 UniProtKB:Q9NZC7-1 20080922 PRO:CNA PR:Q9NZV8-1 potassium voltage-gated channel subfamily D member 2 isoform 1 (human) hKCND2/iso:1 located_in GO:0009986 cell surface PMID:12493773 IDA NCBITaxon:9606 UniProtKB:Q9NZV8-1 20080601 PRO:CNA PR:Q9NZV8-1 potassium voltage-gated channel subfamily D member 2 isoform 1 (human) hKCND2/iso:1 acts_upstream_of_or_within GO:0001508 action potential PMID:11102480 IDA NCBITaxon:9606 UniProtKB:Q9NZV8-1 20080601 PRO:CNA PR:Q9NZV8-1 potassium voltage-gated channel subfamily D member 2 isoform 1 (human) hKCND2/iso:1 acts_upstream_of_or_within GO:0007268 chemical synaptic transmission PMID:11102480 IDA NCBITaxon:9606 UniProtKB:Q9NZV8-1 20080601 PRO:CNA PR:Q9QUJ7-1 long-chain-fatty-acid--CoA ligase 4 isoform 1 (mouse) mACSL4/iso:1 acts_upstream_of_or_within GO:0030182 neuron differentiation MGI_ref:5316151|PMID:22366036 IMP NCBITaxon:10090 MGI:1354713 20130925 MGI:MGI PR:Q9QUQ5 short transient receptor potential channel 4 (mouse) capacitative calcium entry channel Trp4 (mouse)|mTRPC4|receptor-activated cation channel TRP4 (mouse)|Trpc4|TrpC4 (mouse)|Trrp4 located_in GO:0005901 caveola PMID:11897792 EXP NCBITaxon:10090 UniProtKB:Q9QUQ5 20080701 mgi:HJD PR:Q9QUQ5 short transient receptor potential channel 4 (mouse) capacitative calcium entry channel Trp4 (mouse)|mTRPC4|receptor-activated cation channel TRP4 (mouse)|Trpc4|TrpC4 (mouse)|Trrp4 acts_upstream_of_or_within GO:0014051 gamma-aminobutyric acid secretion PMID:14668438 EXP NCBITaxon:10090 UniProtKB:Q9QUQ5 20080701 mgi:HJD PR:Q9QUQ5-1 short transient receptor potential channel 4 isoform alpha (mouse) mTRPC4/iso:Alpha enables GO:0015279 store-operated calcium channel activity MGI_ref:3525810|PMID:15044151 IMP NCBITaxon:10090 MGI:109525 20080702 MGI:MGI occurs_in(CL:0000650) PR:Q9QUQ5-1 short transient receptor potential channel 4 isoform alpha (mouse) mTRPC4/iso:Alpha located_in GO:0005886 plasma membrane MGI_ref:3525810|PMID:15044151 IDA NCBITaxon:10090 MGI:109525 20080702 MGI:MGI part_of(CL:0000650) PR:Q9QXE4-2 tumor protein p53-inducible nuclear protein 1 isoform 2 (mouse) mTP53INP1/iso:2|tumor protein p53-inducible nuclear protein 1 isoform SIP18 (mouse) acts_upstream_of_or_within GO:2001235 positive regulation of apoptotic signaling pathway MGI_ref:3612718|PMID:16044147 IGI NCBITaxon:10090 MGI:1336991 MGI:1926609 20130617 MGI:MGI PR:Q9QXJ1-1 amyloid beta precursor protein binding family B member 1 isoform 1 (mouse) amyloid beta A4 precursor protein-binding family B member 1 isoform 1 (mouse)|mAPBB1/iso:1 acts_upstream_of_or_within GO:0008542 visual learning MGI_ref:3522016|PMID:14689444 IMP NCBITaxon:10090 MGI_allele:3514266 MGI:107765 20080811 MGI:MGI PR:Q9QXZ9-1 melanopsin isoform 1 (mouse) melanopsin 4 long form (mouse)|mOPN4/iso:1|Opn4L (mouse) enables GO:0008020 G protein-coupled photoreceptor activity MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI occurs_in(CL:0000740) PR:Q9QXZ9-1 melanopsin isoform 1 (mouse) melanopsin 4 long form (mouse)|mOPN4/iso:1|Opn4L (mouse) located_in GO:0005886 plasma membrane MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI part_of(CL:0000740) PR:Q9QXZ9-1 melanopsin isoform 1 (mouse) melanopsin 4 long form (mouse)|mOPN4/iso:1|Opn4L (mouse) acts_upstream_of_or_within GO:0016056 rhodopsin mediated signaling pathway MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI occurs_in(CL:0000740) PR:Q9QXZ9-2 melanopsin isoform 2 (mouse) melanopsin 4 short form (mouse)|mOPN4/iso:2|Opn4S (mouse) enables GO:0008020 G protein-coupled photoreceptor activity MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI occurs_in(CL:0000740) PR:Q9QXZ9-2 melanopsin isoform 2 (mouse) melanopsin 4 short form (mouse)|mOPN4/iso:2|Opn4S (mouse) located_in GO:0005886 plasma membrane MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI part_of(CL:0000740) PR:Q9QXZ9-2 melanopsin isoform 2 (mouse) melanopsin 4 short form (mouse)|mOPN4/iso:2|Opn4S (mouse) acts_upstream_of_or_within GO:0016056 rhodopsin mediated signaling pathway MGI_ref:4438311|PMID:19793992 IDA NCBITaxon:10090 MGI:1353425 20130111 MGI:MGI occurs_in(CL:0000740) PR:Q9QY06-1 unconventional myosin-IXb isoform 1 (mouse) mMYO9B/iso:1 located_in GO:0001726 ruffle MGI_ref:3720403|PMID:17314409 IDA NCBITaxon:10090 MGI:106624 20120710 MGI:MGI PR:Q9QY06-3 unconventional myosin-IXb isoform 3 (mouse) mMYO9B/iso:3|unconventional myosin-IXb isoform C (mouse) located_in GO:0001726 ruffle MGI_ref:3720403|PMID:17314409 IDA NCBITaxon:10090 MGI:106624 20140515 MGI:MGI PR:Q9QYS9-6 KH domain-containing RNA-binding protein QKI isoform 6 (mouse) mQKI/iso:6|protein quaking isoform QKI-7B (mouse) enables GO:0003729 mRNA binding MGI_ref:5316962|PMID:20631256 IDA NCBITaxon:10090 MGI:97837 20140625 MGI:MGI has_direct_input(RefSeq:NM_011715) PR:Q9QYS9-6 KH domain-containing RNA-binding protein QKI isoform 6 (mouse) mQKI/iso:6|protein quaking isoform QKI-7B (mouse) acts_upstream_of_or_within GO:0061158 3'-UTR-mediated mRNA destabilization MGI_ref:5316962|PMID:20631256 IDA NCBITaxon:10090 MGI:97837 20140625 MGI:MGI has_direct_input(RefSeq:NM_011715) PR:Q9QZ06-1 Toll-interacting protein isoform 1 (mouse) mTOLLIP/iso:1|tollip.mu (mouse) acts_upstream_of_or_within GO:0006954 inflammatory response PMID:10854325 EXP NCBITaxon:10090 UniProtKB:Q9QZ06-1 20110620 PRO:CNA PR:Q9QZ06-1 Toll-interacting protein isoform 1 (mouse) mTOLLIP/iso:1|tollip.mu (mouse) acts_upstream_of_or_within GO:0034122 negative regulation of toll-like receptor signaling pathway PMID:10854325 EXP NCBITaxon:10090 UniProtKB:Q9QZ06-1 20110620 PRO:CNA PR:Q9QZQ8-2 core histone macro-H2A.1 isoform 1 (mouse) mH2AFY/iso:1 acts_upstream_of_or_within GO:0019216 regulation of lipid metabolic process MGI_ref:5637446|PMID:25526730 IDA NCBITaxon:10090 MGI:1349392 20150605 MGI:MGI PR:Q9R0N6-1 synaptotagmin-8 isoform 1 (mouse) mSYT8/iso:1 located_in GO:0031982 vesicle MGI_ref:4943405|PMID:16386321 IDA NCBITaxon:10090 MGI:1859867 20110407 MGI:MGI PR:Q9R0N6-2 synaptotagmin-8 isoform 2 (mouse) mSYT8/iso:2 located_in GO:0005737 cytoplasm MGI_ref:4943405|PMID:16386321 IDA NCBITaxon:10090 MGI:1859867 20110407 MGI:MGI PR:Q9R0X0-1 mediator of RNA polymerase II transcription subunit 20 isoform 1 (mouse) mMED20/iso:1 part_of GO:0016592 mediator complex MGI_ref:4462751|PMID:20508642 IDA NCBITaxon:10090 MGI:1929648 20120523 MGI:MGI PR:Q9R229-1 bone morphogenetic protein 10 isoform 1 (mouse) mBMP10/iso:1 acts_upstream_of_or_within GO:0007507 heart development PMID:15073151 IDA NCBITaxon:10090 UniProtKB:Q9R229-1 20080301 PRO:CNA PR:Q9R244 short transient receptor potential channel 2 (mouse) mTrp2|mTrpc2|transient receptor protein 2 (mouse)|TRP-2 (mouse)|Trp2|Trpc2|TrpC2 (mouse)|Trrp2 NOT acts_upstream_of_or_within GO:0015279 store-operated calcium channel activity PMID:10998353 IDA NCBITaxon:10090 UniProtKB:Q9R244 20081110 mgi:HJD PR:Q9R244-1 short transient receptor potential channel 2 isoform 1 (mouse) mTrpc2/iso:1|short transient receptor potential channel 2 isoform A (mouse) enables GO:0005516 calmodulin binding MGI_ref:2652910|PMID:12601176 IDA NCBITaxon:10090 MGI:109527 20081006 MGI:MGI PR:Q9R244-2 short transient receptor potential channel 2 isoform 2 (mouse) mTrpc2/iso:2|short transient receptor potential channel 2 isoform B (mouse) enables GO:0005516 calmodulin binding PMID:12601176 IDA NCBITaxon:10090 UniProtKB:Q9R244-2 20081110 mgi:HJD PR:Q9R244-3 short transient receptor potential channel 2 isoform 3 (mouse) mTrpc2/iso:3|short transient receptor potential channel 2 isoform Alpha (mouse) located_in GO:0000139 Golgi membrane MGI_ref:1913270|PMID:10998353 IDA NCBITaxon:10090 MGI:109527 20111221 MGI:MGI PR:Q9R244-3 short transient receptor potential channel 2 isoform 3 (mouse) mTrpc2/iso:3|short transient receptor potential channel 2 isoform Alpha (mouse) located_in GO:0005635 nuclear envelope MGI_ref:1913270|PMID:10998353 IDA NCBITaxon:10090 MGI:109527 20080513 MGI:MGI PR:Q9R244-3 short transient receptor potential channel 2 isoform 3 (mouse) mTrpc2/iso:3|short transient receptor potential channel 2 isoform Alpha (mouse) located_in GO:0005789 endoplasmic reticulum membrane MGI_ref:1913270|PMID:10998353 IDA NCBITaxon:10090 MGI:109527 20080513 MGI:MGI PR:Q9R244-4 short transient receptor potential channel 2 isoform 4 (mouse) mTrpc2/iso:4|short transient receptor potential channel 2 isoform Beta (mouse) located_in GO:0000139 Golgi membrane PMID:10998353 IDA NCBITaxon:10090 UniProtKB:Q9R244-4 20081110 mgi:HJD PR:Q9R244-4 short transient receptor potential channel 2 isoform 4 (mouse) mTrpc2/iso:4|short transient receptor potential channel 2 isoform Beta (mouse) located_in GO:0005635 nuclear envelope MGI_ref:1913270|PMID:10998353 IDA NCBITaxon:10090 MGI:109527 20111221 MGI:MGI PR:Q9R244-4 short transient receptor potential channel 2 isoform 4 (mouse) mTrpc2/iso:4|short transient receptor potential channel 2 isoform Beta (mouse) located_in GO:0005789 endoplasmic reticulum membrane MGI_ref:1913270|PMID:10998353 IDA NCBITaxon:10090 MGI:109527 20111221 MGI:MGI PR:Q9SAR0 1-aminocyclopropane-1-carboxylate synthase 6 (Arabidopsis thaliana) ACC synthase 6 (Arabidopsis thaliana)|ACC6|ACS6|At-ACS6|At4g11280|F8L21.70|S-adenosyl-L-methionine methylthioadenosine-lyase 6 (Arabidopsis thaliana) acts_upstream_of_or_within GO:0010365 positive regulation of ethylene biosynthetic process PMID:15539472|PMID:18182027|PMID:20659280 EXP NCBITaxon:3702 UniProtKB:Q9SAR0 20140402 PRO:LVM PR:Q9TV66-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform r1 (rabbit) rabbit-HCN4/iso:r1 located_in GO:0005886 plasma membrane PMID:15123648 IDA NCBITaxon:9986 UniProtKB:Q9TV66-1 20080601 PRO:CNA PR:Q9UBF6-2 RING-box protein 2 isoform 2 (human) hRNF7/iso:2|RING-box protein 2 isoform SAG-v (human) NOT part_of GO:0000151 ubiquitin ligase complex PMID:11506706 IDA NCBITaxon:9606 UniProtKB:Q9UBF6-2 20080301 PRO:CNA PR:Q9UBN4-1 short transient receptor potential channel 4 isoform alpha (human) hTRPC4/iso:Alpha enables GO:0042802 identical protein binding PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-1 20081015 PRO:CNA PR:Q9UBN4-1 short transient receptor potential channel 4 isoform alpha (human) hTRPC4/iso:Alpha located_in GO:0005886 plasma membrane PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-1 20081015 PRO:CNA PR:Q9UBN4-1 short transient receptor potential channel 4 isoform alpha (human) hTRPC4/iso:Alpha contributes_to enables GO:0015279 store-operated calcium channel activity PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-1 20081015 PRO:CNA PR:Q9UBN4-2 short transient receptor potential channel 4 isoform beta (human) hTRPC4/iso:Beta enables GO:0042802 identical protein binding PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-2 20081015 PRO:CNA PR:Q9UBN4-2 short transient receptor potential channel 4 isoform beta (human) hTRPC4/iso:Beta located_in GO:0005886 plasma membrane PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-2 20081015 PRO:CNA PR:Q9UBN4-2 short transient receptor potential channel 4 isoform beta (human) hTRPC4/iso:Beta contributes_to enables GO:0015279 store-operated calcium channel activity PMID:11713258 IDA NCBITaxon:9606 UniProtKB:Q9UBN4-2 20081015 PRO:CNA PR:Q9UBS0-1 ribosomal protein S6 kinase beta-2 isoform 1 (human) hRPS6KB2/iso:1 acts_upstream_of_or_within GO:0006412 translation PMID:9804755 TAS NCBITaxon:9606 UniProtKB:Q9UBS0-1 20080301 PRO:CNA PR:Q9UBS0-1 ribosomal protein S6 kinase beta-2 isoform 1 (human) hRPS6KB2/iso:1 acts_upstream_of_or_within GO:0007165 signal transduction PMID:9804755 TAS NCBITaxon:9606 UniProtKB:Q9UBS0-1 20080301 PRO:CNA PR:Q9UGI6-1 small conductance calcium-activated potassium channel protein 3 isoform 1 (human) hKCNN3/iso:1 located_in GO:0009986 cell surface PMID:11395478 IDA NCBITaxon:9606 UniProtKB:Q9UGI6-1 20080601 PRO:CNA PR:Q9UK17-1 potassium voltage-gated channel subfamily D member 3 isoform 1 (human) hKCND3/iso:1|potassium voltage-gated channel subfamily D member 3 isoform KCND3L (human)|potassium voltage-gated channel subfamily D member 3 isoform Long (human) contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PMID:8734615|PMID:9843794 IDA NCBITaxon:9606 UniProtKB:Q9UK17-1 20080601 PRO:CNA PR:Q9UK17-2 potassium voltage-gated channel subfamily D member 3 isoform 2 (human) hKCND3/iso:2|potassium voltage-gated channel subfamily D member 3 isoform KCND3S (human)|potassium voltage-gated channel subfamily D member 3 isoform Short (human) contributes_to enables GO:0005250 A-type (transient outward) potassium channel activity PMID:9843794 IDA NCBITaxon:9606 UniProtKB:Q9UK17-2 20080601 PRO:CNA PR:Q9UL51 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (human) BCNG-2 (human)|BCNG2|brain cyclic nucleotide-gated channel 2 (human)|HCN2|hHCN2 enables GO:0005261 monoatomic cation channel activity PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9UL51 20080601 PRO:CNA PR:Q9UL51 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (human) BCNG-2 (human)|BCNG2|brain cyclic nucleotide-gated channel 2 (human)|HCN2|hHCN2 acts_upstream_of_or_within GO:0006812 monoatomic cation transport PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9UL51 20080601 PRO:CNA PR:Q9UL51 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (human) BCNG-2 (human)|BCNG2|brain cyclic nucleotide-gated channel 2 (human)|HCN2|hHCN2 acts_upstream_of_or_within GO:0006936 muscle contraction PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9UL51 20080601 PRO:CNA PR:Q9UL51 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (human) BCNG-2 (human)|BCNG2|brain cyclic nucleotide-gated channel 2 (human)|HCN2|hHCN2 acts_upstream_of_or_within GO:0007267 cell-cell signaling PMID:9630217 IDA NCBITaxon:9606 UniProtKB:Q9UL51 20080601 PRO:CNA PR:Q9UQ05-1 potassium voltage-gated channel subfamily H member 4 isoform 1 (human) hKCNH4/iso:1 part_of GO:0008076 voltage-gated potassium channel complex PMID:10455180 IDA NCBITaxon:9606 UniProtKB:Q9UQ05-1 20080601 PRO:CNA PR:Q9WTK7-1 serine/threonine-protein kinase STK11 isoform 1 (mouse) mLKB1(L)|mLKB1L|mSTK11/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:Q9WTK7-1 serine/threonine-protein kinase STK11 isoform 1 (mouse) mLKB1(L)|mLKB1L|mSTK11/iso:1 located_in GO:0016020 membrane MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:Q9WTK7-1 serine/threonine-protein kinase STK11 isoform 1 (mouse) mLKB1(L)|mLKB1L|mSTK11/iso:1 acts_upstream_of_or_within GO:0032147 activation of protein kinase activity MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI regulates_o_occurs_in(MA:0000411) PR:Q9WTK7-2 serine/threonine-protein kinase STK11 isoform 2 (mouse) mLKB1(S)|mLKB1S|mSTK11/iso:2 located_in GO:0005737 cytoplasm MGI_ref:3836081|PMID:18854309 IDA NCBITaxon:10090 MGI:1341870 20130701 MGI:MGI part_of(MA:0000411) PR:Q9WTN3-1 sterol regulatory element-binding protein 1 isoform 1 (mouse) mSREBF1/iso:1|SREBP-1A (mouse) enables GO:0000976 transcription cis-regulatory region binding MGI_ref:2177036|PMID:11739104 IDA NCBITaxon:10090 MGI:107606 20130206 MGI:MGI has_participant(MGI:MGI:1890410) PR:Q9WTN3-3 sterol regulatory element-binding protein 1 isoform 3 (mouse) mSREBF1/iso:3|SREBP-1C (mouse) enables GO:0000976 transcription cis-regulatory region binding MGI_ref:2177036|PMID:11739104 IDA NCBITaxon:10090 MGI:107606 20140514 MGI:MGI has_participant(MGI:MGI:1890410) PR:Q9WTX5-1 S-phase kinase-associated protein 1 isoform 1 (mouse) mSKP1/iso:1 enables GO:0005515 protein binding PR:P62137-1 PMID:17274640 IPI NCBITaxon:10090 UniProtKB:Q9WTX5-1 20080301 PRO:CNA PR:Q9WTX5-1 S-phase kinase-associated protein 1 isoform 1 (mouse) mSKP1/iso:1 enables GO:0005515 protein binding PR:P63087-1 PMID:17274640 IPI NCBITaxon:10090 UniProtKB:Q9WTX5-1 20080301 PRO:CNA PR:Q9WTX5-1 S-phase kinase-associated protein 1 isoform 1 (mouse) mSKP1/iso:1 part_of GO:0019005 SCF ubiquitin ligase complex PMID:12665572 IDA NCBITaxon:10090 UniProtKB:Q9WTX5-1 20080301 PRO:CNA PR:Q9WTZ1-1 RING-box protein 2 isoform 1 (mouse) mRNF7/iso:1 located_in GO:0005634 nucleus PMID:10082581 IDA NCBITaxon:10090 UniProtKB:Q9WTZ1-1 20080301 PRO:CNA PR:Q9WTZ1-1 RING-box protein 2 isoform 1 (mouse) mRNF7/iso:1 located_in GO:0005737 cytoplasm PMID:10082581 IDA NCBITaxon:10090 UniProtKB:Q9WTZ1-1 20080301 PRO:CNA PR:Q9WTZ1-1 RING-box protein 2 isoform 1 (mouse) mRNF7/iso:1 acts_upstream_of_or_within GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress PMID:10082581 IDA NCBITaxon:10090 UniProtKB:Q9WTZ1-1 20080301 PRO:CNA PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse) mTRPC7/iso:1 located_in GO:0016020 membrane PMID:10488066 IC NCBITaxon:10090 GO:0015279 UniProtKB:Q9WVC5-1 20080923 mgi:HJD PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse) mTRPC7/iso:1 acts_upstream_of_or_within GO:0006816 calcium ion transport PMID:10488066 IDA NCBITaxon:10090 UniProtKB:Q9WVC5-1 20080923 mgi:HJD PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse) mTRPC7/iso:1 contributes_to enables GO:0005262 calcium channel activity PMID:10488066 IDA NCBITaxon:10090 UniProtKB:Q9WVC5-1 20080923 mgi:HJD PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse) mTRPC7/iso:1 contributes_to enables GO:0006828 manganese ion transport PMID:10488066 IDA NCBITaxon:10090 UniProtKB:Q9WVC5-1 20080923 mgi:HJD PR:Q9Y3Q4-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform 1 (human) hHCN4/iso:1 enables GO:0005261 monoatomic cation channel activity PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9Y3Q4-1 20080601 PRO:CNA PR:Q9Y3Q4-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform 1 (human) hHCN4/iso:1 acts_upstream_of_or_within GO:0006812 monoatomic cation transport PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9Y3Q4-1 20080601 PRO:CNA PR:Q9Y3Q4-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform 1 (human) hHCN4/iso:1 acts_upstream_of_or_within GO:0006936 muscle contraction PMID:10228147 IDA NCBITaxon:9606 UniProtKB:Q9Y3Q4-1 20080601 PRO:CNA PR:Q9Y572 receptor-interacting serine/threonine-protein kinase 3 (human) hRIPK3|receptor-interacting protein 3 (human)|RIP-3 (human)|RIP-like protein kinase 3 (human)|RIP3|RIPK3 located_in GO:0005737 cytoplasm Reactome:REACT_22021 EXP NCBITaxon:9606 20130430 PRO:CNA PR:Q9Y616-1 interleukin-1 receptor-associated kinase 3 isoform 1 (human) hIRAK3/iso:1 enables GO:0005515 protein binding PR:Q99836 PMID:10383454 IPI NCBITaxon:9606 UniProtKB:Q9Y616-1 20110620 PRO:CNA PR:Q9Y616-1 interleukin-1 receptor-associated kinase 3 isoform 1 (human) hIRAK3/iso:1 acts_upstream_of_or_within GO:0034122 negative regulation of toll-like receptor signaling pathway PMID:10383454 EXP NCBITaxon:9606 UniProtKB:Q9Y616-1 20110620 PRO:CNA PR:Q9Y6D9 mitotic spindle assembly checkpoint protein MAD1 (human) hMAD1|hMAD1L1|HsMAD1|MAD1|MAD1-like protein 1 (human)|MAD1L1|mitotic arrest deficient 1-like protein 1 (human)|mitotic checkpoint MAD1 protein homolog (human)|Tax-binding protein 181 (human)|TXBP181 enables GO:0005515 protein binding PR:O43683 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:Q9Y6D9 20121112 PRO:KER PR:Q9Y6D9 mitotic spindle assembly checkpoint protein MAD1 (human) hMAD1|hMAD1L1|HsMAD1|MAD1|MAD1-like protein 1 (human)|MAD1L1|mitotic arrest deficient 1-like protein 1 (human)|mitotic checkpoint MAD1 protein homolog (human)|Tax-binding protein 181 (human)|TXBP181 enables GO:0005515 protein binding PR:O43684 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:Q9Y6D9 20121112 PRO:KER PR:Q9Y6D9 mitotic spindle assembly checkpoint protein MAD1 (human) hMAD1|hMAD1L1|HsMAD1|MAD1|MAD1-like protein 1 (human)|MAD1L1|mitotic arrest deficient 1-like protein 1 (human)|mitotic checkpoint MAD1 protein homolog (human)|Tax-binding protein 181 (human)|TXBP181 enables GO:0005515 protein binding PR:Q13257 PMID:10198256 IPI NCBITaxon:9606 UniProtKB:Q9Y6D9 20121112 PRO:KER PR:Q9Y6D9 mitotic spindle assembly checkpoint protein MAD1 (human) hMAD1|hMAD1L1|HsMAD1|MAD1|MAD1-like protein 1 (human)|MAD1L1|mitotic arrest deficient 1-like protein 1 (human)|mitotic checkpoint MAD1 protein homolog (human)|Tax-binding protein 181 (human)|TXBP181 located_in GO:0000776 kinetochore PMID:20624902 EXP NCBITaxon:9606 UniProtKB:Q9Y6D9 20121112 PRO:KER PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse) mCX3CR1/iso:1 acts_upstream_of_or_within GO:0002282 microglial cell activation involved in immune response MGI_ref:3639805|PMID:16732273 IMP NCBITaxon:10090 MGI_allele:2670351 MGI:1333815 20090622 MGI:MGI PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse) mCX3CR1/iso:1 acts_upstream_of_or_within GO:0019221 cytokine-mediated signaling pathway MGI_ref:3833195|PMID:18971423 IMP NCBITaxon:10090 MGI:1333815 20090622 MGI:MGI PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse) mCX3CR1/iso:1 acts_upstream_of_or_within GO:0021795 cerebral cortex cell migration MGI_ref:3639805|PMID:16732273 IMP NCBITaxon:10090 MGI_allele:2670351 MGI:1333815 20090622 MGI:MGI occurs_in(MA:0000905),results_in_movement_of(CL:0000129) PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse) mCX3CR1/iso:1 acts_upstream_of_or_within GO:0048246 macrophage chemotaxis MGI_ref:3777228|PMID:18322241 IMP NCBITaxon:10090 MGI_allele:3608773 MGI:1333815 20090622 MGI:MGI PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse) mCX3CR1/iso:1 acts_upstream_of_or_within GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand MGI_ref:3833195|PMID:18971423 IMP NCBITaxon:10090 MGI_allele:2670351 MGI:1333815 20130621 MGI:MGI PR:Q9Z0P7 suppressor of fused homolog (mouse) mSUFU|Sufu acts_upstream_of_or_within GO:0021513 spinal cord dorsal/ventral patterning PMID:16459298 IMP NCBITaxon:10090 UniProtKB:Q9Z0P7 20091013 PRO:HJD PR:Q9Z0P7 suppressor of fused homolog (mouse) mSUFU|Sufu acts_upstream_of_or_within GO:0043588 skin development PMID:16459298 IMP NCBITaxon:10090 UniProtKB:Q9Z0P7 20091013 PRO:HJD PR:Q9Z0P7 suppressor of fused homolog (mouse) mSUFU|Sufu acts_upstream_of_or_within GO:0045879 negative regulation of smoothened signaling pathway PMID:16459298 IMP NCBITaxon:10090 MGI_allele:3619046 UniProtKB:Q9Z0P7 20091013 PRO:HJD PR:Q9Z0P7-1 suppressor of fused homolog isoform 1 (mouse) mSUFU/iso:1 enables GO:0005515 protein binding PR:P47806 MGI_ref:1861566|PMID:10920228 IPI NCBITaxon:10090 MGI:1345643 20091014 MGI:MGI PR:Q9Z0P7-1 suppressor of fused homolog isoform 1 (mouse) mSUFU/iso:1 enables GO:0005515 protein binding PR:Q61602 MGI_ref:1861566|PMID:10920228 IPI NCBITaxon:10090 MGI:1345643 20091014 MGI:MGI PR:Q9Z0P7-1 suppressor of fused homolog isoform 1 (mouse) mSUFU/iso:1 located_in GO:0005634 nucleus MGI_ref:3692156|PMID:16254602 IDA NCBITaxon:10090 MGI:1345643 20091014 MGI:MGI PR:Q9Z0P7-1 suppressor of fused homolog isoform 1 (mouse) mSUFU/iso:1 located_in GO:0005737 cytoplasm MGI_ref:3608582|PMID:16316410 IDA NCBITaxon:10090 MGI:1345643 20091013 MGI:MGI PR:Q9Z0P7-1 suppressor of fused homolog isoform 1 (mouse) mSUFU/iso:1 located_in GO:0005929 cilium MGI_ref:3692156|PMID:16254602 IDA NCBITaxon:10090 MGI:1345643 20091014 MGI:MGI PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) enables GO:0005515 protein binding PR:P10071 MGI_ref:1346364|PMID:10531011 IPI NCBITaxon:10090 UniProtKB:Q9Z0P7-4 20091013 MGI:MGI Note=Binding between proteins from heterogeneous species PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) enables GO:0005515 protein binding PR:P47806 MGI_ref:1346364|PMID:10531011 IPI NCBITaxon:10090 UniProtKB:Q9Z0P7-4 20091013 MGI:MGI PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) enables GO:0005515 protein binding PR:Q0VGT2 MGI_ref:1346364|PMID:10531011 IPI NCBITaxon:10090 UniProtKB:Q9Z0P7-4 20091013 MGI:MGI PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) located_in GO:0005737 cytoplasm MGI_ref:1346364|PMID:10531011 IDA NCBITaxon:10090 MGI:1345643 20091013 MGI:MGI PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:1346364|PMID:10531011 IDA NCBITaxon:10090 MGI:1345643 20091013 MGI:MGI PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse) mSUFU/iso:4|suppressor of fused homolog isoform SU(FU)-XL (mouse) acts_upstream_of_or_within GO:0045879 negative regulation of smoothened signaling pathway MGI_ref:1346364|PMID:10531011 IDA NCBITaxon:10090 MGI:1345643 20091013 MGI:MGI PR:Q9Z0V2-1 potassium voltage-gated channel subfamily D member 2 isoform 1 (mouse) mKCND2/iso:1 located_in GO:0005783 endoplasmic reticulum PMID:12829703 IDA NCBITaxon:10090 UniProtKB:Q9Z0V2-1 20080601 PRO:CNA PR:Q9Z1M4-1 ribosomal protein S6 kinase beta-2 isoform 1 (mouse) mRPS6KB2/iso:1 enables GO:0004674 protein serine/threonine kinase activity PMID:15249583 IDA NCBITaxon:10090 UniProtKB:Q9Z1M4-1 20080301 PRO:CNA PR:Q9Z1W9-1 STE20/SPS1-related proline-alanine-rich protein kinase isoform 1 (mouse) mSTK39/iso:1 enables GO:0004672 protein kinase activity MGI_ref:5292405|PMID:21907141 IDA NCBITaxon:10090 MGI:1858416 20141015 MGI:MGI has_direct_input(UniProtKB:P55014)|has_direct_input(UniProtKB:P59158) PR:Q9Z1W9-1 STE20/SPS1-related proline-alanine-rich protein kinase isoform 1 (mouse) mSTK39/iso:1 enables GO:0005515 protein binding PR:P55014-4 MGI_ref:5538439|PMID:24133122 IPI NCBITaxon:10090 MGI:1858416 20141009 MGI:MGI PR:Q9Z1X0-1 C-C motif chemokine 27 isoform 1 (mouse) mCCL27/iso:1 located_in GO:0005576 extracellular region MGI_ref:5515357|PMID:10588729 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI PR:Q9Z1X0-1 C-C motif chemokine 27 isoform 1 (mouse) mCCL27/iso:1 acts_upstream_of_or_within GO:0010820 positive regulation of T cell chemotaxis MGI_ref:5515357|PMID:10588729 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI PR:Q9Z1X0-2 C-C motif chemokine 27 isoform 2 (mouse) mCCL27/iso:2|PESKY (mouse) located_in GO:0005634 nucleus MGI_ref:1347714|PMID:10559234 IDA NCBITaxon:10090 MGI:1343459 20131028 MGI:MGI PR:Q9Z1X0-2 C-C motif chemokine 27 isoform 2 (mouse) mCCL27/iso:2|PESKY (mouse) located_in GO:0005634 nucleus MGI_ref:5515359|PMID:12133963 IDA NCBITaxon:10090 MGI:1343459 20131029 MGI:MGI PR:Q9Z206-1 neuroepithelial cell-transforming gene 1 protein isoform 1 (mouse) mNET1/iso:1 enables GO:0031267 small GTPase binding MGI_ref:5471195|PMID:23184663 IDA NCBITaxon:10090 MGI:1927138 20140108 MGI:MGI PR:Q9Z206-2 neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse) mNET1/iso:2|NET1A (mouse) enables GO:0031267 small GTPase binding MGI_ref:5471195|PMID:23184663 IDA NCBITaxon:10090 MGI:1927138 20140108 MGI:MGI PR:Q9Z206-2 neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse) mNET1/iso:2|NET1A (mouse) located_in GO:0005634 nucleus MGI_ref:5471195|PMID:23184663 IDA NCBITaxon:10090 MGI:1927138 20140108 MGI:MGI PR:Q9Z206-2 neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse) mNET1/iso:2|NET1A (mouse) located_in GO:0005886 plasma membrane MGI_ref:5471195|PMID:23184663 IDA NCBITaxon:10090 MGI:1927138 20140108 MGI:MGI localization_dependent_on(UniProtKB:P63001) PR:Q9Z206-2 neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse) mNET1/iso:2|NET1A (mouse) acts_upstream_of_or_within GO:1900026 positive regulation of substrate adhesion-dependent cell spreading MGI_ref:5471195|PMID:23184663 IDA NCBITaxon:10090 MGI:1927138 20140108 MGI:MGI PR:Q9Z2D6-1 methyl-CpG-binding protein 2 isoform 1 (mouse) MECP2a (mouse)|MECP2e2 (mouse)|methyl-CpG-binding protein 2 isoform beta|mMECP2/iso:1 enables GO:0003682 chromatin binding MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20101014 MGI:MGI PR:Q9Z2D6-1 methyl-CpG-binding protein 2 isoform 1 (mouse) MECP2a (mouse)|MECP2e2 (mouse)|methyl-CpG-binding protein 2 isoform beta|mMECP2/iso:1 located_in GO:0005634 nucleus MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20101014 MGI:MGI PR:Q9Z2D6-1 methyl-CpG-binding protein 2 isoform 1 (mouse) MECP2a (mouse)|MECP2e2 (mouse)|methyl-CpG-binding protein 2 isoform beta|mMECP2/iso:1 located_in GO:0000792 heterochromatin MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20101014 MGI:MGI PR:Q9Z2D6-2 methyl-CpG-binding protein 2 isoform 2 (mouse) MECP2b (mouse)|MECP2e1 (mouse)|methyl-CpG-binding protein 2 isoform alpha|mMECP2/iso:2 enables GO:0003682 chromatin binding MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20120126 MGI:MGI PR:Q9Z2D6-2 methyl-CpG-binding protein 2 isoform 2 (mouse) MECP2b (mouse)|MECP2e1 (mouse)|methyl-CpG-binding protein 2 isoform alpha|mMECP2/iso:2 located_in GO:0005634 nucleus MGI_ref:3040528|PMID:15034150 IDA NCBITaxon:10090 MGI:99918 20090410 MGI:MGI PR:Q9Z2D6-2 methyl-CpG-binding protein 2 isoform 2 (mouse) MECP2b (mouse)|MECP2e1 (mouse)|methyl-CpG-binding protein 2 isoform alpha|mMECP2/iso:2 located_in GO:0005634 nucleus MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20120126 MGI:MGI PR:Q9Z2D6-2 methyl-CpG-binding protein 2 isoform 2 (mouse) MECP2b (mouse)|MECP2e1 (mouse)|methyl-CpG-binding protein 2 isoform alpha|mMECP2/iso:2 located_in GO:0000792 heterochromatin MGI_ref:3805223|PMID:18334558 IDA NCBITaxon:10090 MGI:99918 20120126 MGI:MGI PR:Q9Z2S7-1 TSC22 domain family protein 3 isoform 1 (mouse) mTSC22D3/iso:1|Tilz3b (mouse) enables GO:0043426 MRF binding PR:P10085 MGI_ref:4838954|PMID:20124407 IPI NCBITaxon:10090 MGI:1196284 20140514 MGI:MGI PR:Q9Z2S7-1 TSC22 domain family protein 3 isoform 1 (mouse) mTSC22D3/iso:1|Tilz3b (mouse) located_in GO:0005634 nucleus MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20120215 MGI:MGI PR:Q9Z2S7-1 TSC22 domain family protein 3 isoform 1 (mouse) mTSC22D3/iso:1|Tilz3b (mouse) located_in GO:0005737 cytoplasm MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20120215 MGI:MGI PR:Q9Z2S7-1 TSC22 domain family protein 3 isoform 1 (mouse) mTSC22D3/iso:1|Tilz3b (mouse) acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20120215 MGI:MGI has_regulation_target(MGI:MGI:97276) PR:Q9Z2S7-1 TSC22 domain family protein 3 isoform 1 (mouse) mTSC22D3/iso:1|Tilz3b (mouse) acts_upstream_of_or_within GO:0048642 negative regulation of skeletal muscle tissue development MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20120215 MGI:MGI PR:Q9Z2S7-4 TSC22 domain family protein 3 isoform 4 (mouse) L-GLITZ (mouse)|Long glucocorticoid-induced leucine zipper protein (mouse)|mTSC22D3/iso:4 enables GO:0043426 MRF binding PR:P10085 MGI_ref:4838954|PMID:20124407 IPI NCBITaxon:10090 MGI:1196284 20120215 MGI:MGI PR:Q9Z2S7-4 TSC22 domain family protein 3 isoform 4 (mouse) L-GLITZ (mouse)|Long glucocorticoid-induced leucine zipper protein (mouse)|mTSC22D3/iso:4 located_in GO:0005634 nucleus MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20110119 MGI:MGI PR:Q9Z2S7-4 TSC22 domain family protein 3 isoform 4 (mouse) L-GLITZ (mouse)|Long glucocorticoid-induced leucine zipper protein (mouse)|mTSC22D3/iso:4 located_in GO:0005737 cytoplasm MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20110119 MGI:MGI PR:Q9Z2S7-4 TSC22 domain family protein 3 isoform 4 (mouse) L-GLITZ (mouse)|Long glucocorticoid-induced leucine zipper protein (mouse)|mTSC22D3/iso:4 acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20110119 MGI:MGI has_regulation_target(MGI:MGI:97276) PR:Q9Z2S7-4 TSC22 domain family protein 3 isoform 4 (mouse) L-GLITZ (mouse)|Long glucocorticoid-induced leucine zipper protein (mouse)|mTSC22D3/iso:4 acts_upstream_of_or_within GO:0048642 negative regulation of skeletal muscle tissue development MGI_ref:4838954|PMID:20124407 IDA NCBITaxon:10090 MGI:1196284 20110119 MGI:MGI PR:Q9Z351-10 potassium voltage-gated channel subfamily KQT member 2 isoform 10 (mouse) mKCNQ2/iso:10|potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.10 (mouse) NOT enables GO:0022832 voltage-gated channel activity PMID:9666519 IDA NCBITaxon:10090 UniProtKB:Q9Z351-10 20080601 PRO:CNA PR:Q9Z351-11 potassium voltage-gated channel subfamily KQT member 2 isoform 11 (mouse) mKCNQ2/iso:11|potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.11 (mouse) NOT enables GO:0022832 voltage-gated channel activity PMID:9666519 IDA NCBITaxon:10090 UniProtKB:Q9Z351-11 20080601 PRO:CNA PR:Q9Z351-12 potassium voltage-gated channel subfamily KQT member 2 isoform 12 (mouse) mKCNQ2/iso:12 enables GO:0005516 calmodulin binding PMID:12223552 IDA NCBITaxon:10090 UniProtKB:Q9Z351-12 20080601 PRO:CNA PR:Q9Z351-12 potassium voltage-gated channel subfamily KQT member 2 isoform 12 (mouse) mKCNQ2/iso:12 located_in GO:0009986 cell surface PMID:12223552 IDA NCBITaxon:10090 UniProtKB:Q9Z351-12 20080601 PRO:CNA PR:Q9Z351-12 potassium voltage-gated channel subfamily KQT member 2 isoform 12 (mouse) mKCNQ2/iso:12 part_of GO:0008076 voltage-gated potassium channel complex PMID:12223552 IDA NCBITaxon:10090 UniProtKB:Q9Z351-12 20080601 PRO:CNA PR:Q9Z351-9 potassium voltage-gated channel subfamily KQT member 2 isoform 9 (mouse) mKCNQ2/iso:9|potassium voltage-gated channel subfamily KQT member 2 isoform MKQT2.9 (mouse) NOT enables GO:0022832 voltage-gated channel activity PMID:9666519 IDA NCBITaxon:10090 UniProtKB:Q9Z351-9 20080601 PRO:CNA PR:R4JKA2 anti-Muellerian hormone type-2 receptor isoform Delta2 (mouse) anti-Muellerian hormone type-2 receptor isoform 2 (mouse)|mAMHR2/iso:Delta2 acts_upstream_of_or_within GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway MGI_ref:5499265|PMID:23624077 IDA NCBITaxon:10090 MGI:105062 20140114 MGI:MGI PR:R4JNM3 anti-Muellerian hormone type-2 receptor isoform Delta9/10 (mouse) mAMHR2/iso:Delta9/10 acts_upstream_of_or_within GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway MGI_ref:5499265|PMID:23624077 IDA NCBITaxon:10090 MGI:105062 20140114 MGI:MGI