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Protein Ontology report - Rho-associated protein kinase 2 isoform 1 phosphorylated 1

PR:000000565 - http://purl.obolibrary.org/obo/PR_000000565

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000565

PRO name

Rho-associated protein kinase 2 isoform 1 phosphorylated 1

Synonyms

PRO-Short-label:

EXACT:

ROCK2/iso:1/Phos:1

Definition

"A Rho-associated protein kinase 2 isoform 1 phosphorylated form in which the phosphorylation occurs within the C-terminal region by the action of serine/threonine-protein kinase PLK1." [PMID:17446864]

Comment

Note: Phosphorylation can occur at Ser and/or Thr residues.

PRO Category

modification

Parent

PR:000000462 Rho-associated protein kinase 2 isoform 1 phosphorylated form

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	1	Organism-Modification	1

Term Hierarchy
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DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

modification

PR:000000565 Rho-associated protein kinase 2 isoform 1 phosphorylated 1, ROCK2/iso:1/Phos:1

organism-modification

PR:000036478 Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human), hROCK2/iso:1/Phos:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036478 hROCK2/iso:1/Phos:1 UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046 "A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]	acts_upstream_of_or_within	GO:0006468 protein phosphorylation	PMID:17446864
	enables	GO:0004674 protein serine/threonine kinase activity	PMID:17446864
	located_in	GO:0005634 nucleus	PMID:15302935