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Protein Ontology report - 5-aminolevulinate synthase
PR:000026125 -
http://purl.obolibrary.org/obo/PR_000026125
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000026125
PRO name
5-aminolevulinate synthase
Synonyms
Other
:
EXACT:
5-aminolevulinic acid synthase | ALAS
Definition
"A PLP-dependent alpha-oxoamine synthase whose functional form is the first enzyme in the pathway for synthesis of all tetrapyrroles in non-photosynthetic eukaryotes and alpha-proteobacteria. ALAS catalyzes the decarboxylative condensation of glycine and succinyl-CoA, yielding 5-aminolevulinic acid, free coenzyme-A and CO2." [
PMID:13598764
, PRO:CNA]
PRO Category
family
Parent
PR:000026124
PLP-dependent alpha-oxoamine synthase
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Family
1
Organism-Family
0
Gene
2
Organism-Gene
11
Sequence
2
Organism-Sequence
10
Modification
2
Organism-Modification
5
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
PIRSF:PIRSF000444
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
family
PR:000026125
5-aminolevulinate synthase, hMCCC2/var:MCCB IVS3+5G->T
gene
PR:000003916
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS1
organism-gene
PR:P07997
5-aminolevulinate synthase, non-specific, mitochondrial (chicken), chick-ALAS1
organism-gene
PR:P13195
5-aminolevulinate synthase, non-specific, mitochondrial (rat), rALAS1
organism-sequence
PR:P13195-1
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat), rALAS1/iso:1
organism-gene
PR:P13196
5-aminolevulinate synthase, non-specific, mitochondrial (human), hALAS1
organism-sequence
PR:P13196-1
5-aminolevulinate synthase, non-specific, mitochondrial isoform h1 (human), hALAS1/iso:h1
organism-sequence
PR:P13196-2
5-aminolevulinate synthase, non-specific, mitochondrial isoform h2 (human), hALAS1/iso:h2
organism-modification
PR:000046304
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human), hALAS1/TransPep-
organism-modification
PR:000046305
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human), hALAS1/TransPep-/PyrdoxLys+
organism-modification
PR:000046305
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human), hALAS1/TransPep-/PyrdoxLys+
organism-modification
PR:000066761
5-aminolevulinate synthase, non-specific, mitochondrial methylated 1 (human), hALAS1/Me:1
organism-modification
PR:000078022
5-aminolevulinate synthase, non-specific, mitochondrial methylated 2 (human), hALAS1/Me:2
organism-gene
PR:Q8VC19
5-aminolevulinate synthase, non-specific, mitochondrial (mouse), mALAS1
organism-sequence
PR:Q8VC19-1
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse), mALAS1/iso:1
sequence
PR:000042113
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1, ALAS1/iso:1
organism-sequence
PR:P13195-1
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat), rALAS1/iso:1
organism-sequence
PR:Q8VC19-1
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse), mALAS1/iso:1
modification
PR:000018945
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form, ALAS1/TransPep-
organism-modification
PR:000046304
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human), hALAS1/TransPep-
organism-modification
PR:000046305
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human), hALAS1/TransPep-/PyrdoxLys+
gene
PR:000003917
5-aminolevulinate synthase, erythroid-specific, mitochondrial, ALAS2
organism-gene
PR:O14092
5-aminolevulinate synthase, mitochondrial (Schizosaccharomyces pombe 972h-), Spom972h-ALAS2
organism-gene
PR:P08680
5-aminolevulinate synthase, erythroid-specific, mitochondrial (mouse), mALAS2
organism-sequence
PR:P08680-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse), mALAS2/iso:1
organism-gene
PR:P09950
5-aminolevulinate synthase, mitochondrial (yeast), yALAS2
organism-gene
PR:P22557
5-aminolevulinate synthase, erythroid-specific, mitochondrial (human), hALAS2
organism-sequence
PR:P22557-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human), hALAS2/iso:1
organism-sequence
PR:P22557-2
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h2 (human), hALAS2/iso:h2
organism-sequence
PR:P22557-3
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h3 (human), hALAS2/iso:h3
organism-sequence
PR:P22557-4
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h4 (human), hALAS2/iso:h4
organism-modification
PR:000046306
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human), hALAS2/TransPep-/PyrdoxLys+
organism-gene
PR:Q54UX3
5-aminolevulinate synthase (Dictyostelium discoideum), Dicty-ALAS2
organism-gene
PR:Q63147
5-aminolevulinate synthase, erythroid-specific, mitochondrial (rat), rALAS2
organism-sequence
PR:Q63147-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat), rALAS2/iso:1
organism-gene
PR:Q9YHT4
5-aminolevulinate synthase, erythroid-specific, mitochondrial (zebrafish), z-ALAS2
sequence
PR:000039074
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1, ALAS2/iso:1
organism-sequence
PR:P08680-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse), mALAS2/iso:1
organism-sequence
PR:P22557-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human), hALAS2/iso:1
organism-sequence
PR:Q63147-1
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat), rALAS2/iso:1
modification
PR:000018947
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed form, ALAS2/TransPep-
organism-modification
PR:000046306
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human), hALAS2/TransPep-/PyrdoxLys+