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Protein Ontology report - TIR domain-containing adapter molecule 2 isoform 1

PR:000027197 - http://purl.obolibrary.org/obo/PR_000027197

Protein Forms

Complex

Ontology Information

Show OBO stanza

PRO ID

PR:000027197

PRO name

TIR domain-containing adapter molecule 2 isoform 1

Synonyms

PRO-Short-label:

EXACT:

TICAM2/iso:1

Definition

"A TIR domain-containing adapter molecule 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86XR7-1 or a 1:1 ortholog thereof." [PRO:CNA]

PRO Category

sequence

Parent

PR:000001750 TIR domain-containing adapter molecule 2

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	2
Modification	2	Organism-Modification	2

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

sequence

PR:000027197 TIR domain-containing adapter molecule 2 isoform 1, TICAM2/iso:1

organism-sequence

PR:Q86XR7-1 TIR domain-containing adapter molecule 2 isoform 1 (human), hTICAM2/iso:1

organism-modification

PR:000027201 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated 1 (human), hTICAM2/iso:1/InitMet-/Myr:1

organism-modification

PR:000040891 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human), hTICAM2/iso:1/InitMet-/MyrPhos:1

Yes

organism-sequence

PR:Q8BJQ4-1 TIR domain-containing adapter molecule 2 isoform 1 (mouse), mTICAM2/iso:1

modification

PR:000027199 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed form, TICAM2/iso:1/InitMet-

modification

PR:000027200 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form, TICAM2/iso:1/InitMet-/MyrRes+

organism-modification

PR:000027201 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated 1 (human), hTICAM2/iso:1/InitMet-/Myr:1

organism-modification

PR:000040891 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human), hTICAM2/iso:1/InitMet-/MyrPhos:1

Yes

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TICAM2/iso:1 forms found in complexes

TICAM2/iso:1 Component	Complexes
PR:000040891 hTICAM2/iso:1/InitMet-/MyrPhos:1	PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
	PR:000028678 ticam2:activated TLR4 complex (human)
	PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
	PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)