Protein Ontology

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Protein Ontology report - profilin-2 isoform 1

PR:000037455 - http://purl.obolibrary.org/obo/PR_000037455

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000037455

PRO name

profilin-2 isoform 1

Synonyms

PRO-Short-label:	EXACT:	PFN2/iso:1
Other:	EXACT:	profilin-2soform IIa

Definition

"A profilin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJV2-1 or a 1:1 ortholog thereof." [PMID:11034907, PRO:HJD]

PRO Category

sequence

Parent

PR:000012586 profilin-2

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	2
Modification	0	Organism-Modification	0

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

sequence

PR:000037455 profilin-2 isoform 1, PFN2/iso:1

organism-sequence

PR:P35080-1 profilin-2 isoform 1 (human), hPFN2/iso:1

organism-sequence

PR:Q9JJV2-1 profilin-2 isoform 1 (mouse), mPFN2/iso:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:Q9JJV2-1 mPFN2/iso:1 profilin-2 isoform IIa (mouse) "A profilin-2 isoform 1 that is encoded in the genome of mouse." [PMID:11034907, PRO:HJD]	acts_upstream_of_or_within	GO:0030837 negative regulation of actin filament polymerization	MGI:4844066; PMID:18001770
	located_in	GO:0043195 terminal bouton	MGI:3714870; PMID:17541406