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RACE-PRO
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Protein Ontology report - serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human)
PR:000044819 -
http://purl.obolibrary.org/obo/PR_000044819
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000044819
PRO name
serine/threonine-protein kinase PAK 4 isoform 1 phosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hPAK4/iso:1/Phos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:O96013-1
, Ser-99/Ser-474,
MOD:00046
Definition
"A serine/threonine-protein kinase PAK 4 isoform 1 (human) that has been phosphorylated on a Ser residue that is within a 14-3-3 recognition motif, and a Ser residue that is in the activation loop of the kinase domain and is an autocatalytic phosphorylation site.
UniProtKB:O96013-1
, Ser-99/Ser-474,
MOD:00046
." [
PMID:23841590
, PRO:CNA]
Comment
Evidence=(ECO:0000006,
PMID:23695676
). Kinase=("PAK4";
PR:O96013-1
; Ser-99). Kinase=("PRKD1";
PR:Q15139
; Ser-474). Note: Proteoform created based on papers selected via the eFIP text mining tool. Source of PAK4 organism in
PMID:23841590
is linked to reference
PMID:12637538
.
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:O96013
serine/threonine-protein kinase PAK 4 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000044819
hPAK4/iso:1/Phos:1
UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046
"A serine/threonine-protein kinase PAK 4 isoform 1 (human) that has been phosphorylated on a Ser residue that is within a 14-3-3 recognition motif, and a Ser residue that is in the activation loop of the kinase domain and is an autocatalytic phosphorylation site. UniProtKB:O96013-1, Ser-99/Ser-474, MOD:00046." [PMID:23841590, PRO:CNA]
enables
GO:0071889
14-3-3 protein binding
with
PR:P61981
hYWHAG
PMID:23695676
located_in
GO:0031252
cell leading edge
PMID:23695676