PRO Term |
GO Annotation |
Evidence |
PR:000036477 hROCK2/iso:1/Clv:1 UniProtKB:O75116-1, 1-1131 "A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA] |
acts_upstream_of_or_within | GO:0006468 protein phosphorylation |
PMID:15699075 |
GO:0030036 actin cytoskeleton organization |
PMID:15699075 |
enables | increased GO:0004674 protein serine/threonine kinase activity relative to PR:000002530 ROCK2/iso:1/UnMod |
PMID:15699075 |
located_in | GO:0005622 intracellular anatomical structure |
PMID:15699075 |
PR:000036478 hROCK2/iso:1/Phos:1 UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046 "A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA] |
acts_upstream_of_or_within | GO:0006468 protein phosphorylation |
PMID:17446864 |
enables | GO:0004674 protein serine/threonine kinase activity |
PMID:17446864 |
located_in | GO:0005634 nucleus |
PMID:15302935 |
PR:000036479 hROCK2/iso:1/Phos:2 UniProtKB:O75116-1, Thr-1078, MOD:00047 "A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA] |
acts_upstream_of_or_within | GO:0042770 signal transduction in response to DNA damage |
PMID:17525332 |
PR:O75116-1 hROCK2/iso:1
"A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA] |
acts_upstream_of_or_within | GO:0006468 protein phosphorylation |
PMID:9933571 |
GO:0051260 protein homooligomerization |
PMID:15291762 |
enables | GO:0004674 protein serine/threonine kinase activity |
PMID:9933571 |
GO:0031267 small GTPase binding |
PMID:11350930 |
located_in | GO:0005622 intracellular anatomical structure |
PMID:16574662 |