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Protein Ontology report - bifunctional glutamate/proline--tRNA ligase (mouse)
PR:Q8CGC7 -
http://purl.obolibrary.org/obo/PR_Q8CGC7
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:Q8CGC7
PRO name
bifunctional glutamate/proline--tRNA ligase (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mEPRS
Gene-based
:
RELATED:
Eprs | Eprs1 | Qprs
Other
:
EXACT:
bifunctional aminoacyl-tRNA synthetase (mouse)
Definition
"A bifunctional glutamate/proline--tRNA ligase that is encoded in the genome of mouse." [
OMA:Q8CGC7
,
PMID:15489334
, PRO:HJD]
PRO Category
organism-gene
Parent
PR:000007144
bifunctional glutamate/proline--tRNA ligase
PR:000029032
Mus musculus protein
Gene Template
MGI:97838
Eprs (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
1
Modification
0
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q8CGC7
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q8CGC7
bifunctional glutamate/proline--tRNA ligase (mouse), mEPRS
organism-sequence
PR:Q8CGC7-1
bifunctional glutamate/proline--tRNA ligase isoform 1 (mouse), mEPRS/iso:1
organism-modification
PR:000037785
bifunctional glutamate/proline--tRNA ligase phosphorylated 1 (mouse), mEPRS/Phos:1
Yes
Yes
organism-modification
PR:000037786
bifunctional glutamate/proline--tRNA ligase unphosphorylated 1 (mouse), mEPRS/UnPhos:1
Yes
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mEPRS
forms found in complexes
mEPRS
Component
Complexes
PR:000037785
mEPRS/Phos:1
PR:000037795
GAIT complex (mouse)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037785
mEPRS/Phos:1
UniProtKB:Q8CGC7, Ser-999, MOD:00046 | mEPRS phosphorylated
"A bifunctional glutamate/proline--tRNA ligase (mouse) that has been phosphorylated on a Ser residue in the noncatalytic linker connecting the synthetase cores in an IFN-gamma-dependent manner. UniProtKB:Q8CGC7, Ser-999, MOD:00046." [PMID:23071094, PRO:HJD]
acts_upstream_of_or_within
GO:0071346
cellular response to type II interferon
MGI:5466658
;
PMID:23071094
located_in
GO:0097452
GAIT complex
MGI:5466658
;
PMID:23071094
PR:000037786
mEPRS/UnPhos:1
UniProtKB:Q8CGC7, Ser-999, PR:000026291 | mEPRS unphosphorylated
"A bifunctional glutamate/proline--tRNA ligase (mouse) that lacks phosphorylation at the position equivalent to Ser-999 of the amino acid sequence represented by UniProtKB:Q8CGC7. UniProtKB:Q8CGC7, Ser-999, PR:000026291." [PMID:23071094, PRO:HJD]
located_in
GO:0017101
aminoacyl-tRNA synthetase multienzyme complex
MGI:5466658
;
PMID:23071094
NOT
GO:0097452
GAIT complex
MGI:5466658
;
PMID:23071094