PRO ID |
GO:0002169
Show OBO stanza
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PRO name |
3-methylcrotonyl-CoA carboxylase complex, mitochondrial |
Synonyms |
Other: |
EXACT: |
mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme |
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Definition |
A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.
[GOC:bf, GOC:hjd, PMID:15868465, PMID:17360195, PMID:22869039]
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PRO Category |
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Parent |
GO:0032991 protein-containing complex |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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