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Protein Ontology Report - 3-methylcrotonyl-CoA carboxylase complex, mitochondrial

GO:0002169 -
Ontology Information
PRO ID GO:0002169 Show OBO stanza
PRO name 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
Other: EXACT: mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme
Definition A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA. [GOC:bf, GOC:hjd, PMID:15868465, PMID:17360195, PMID:22869039]
PRO Category
Parent GO:0032991 protein-containing complex
Term Hierarchy Visualization DAG     OLS     Cytoscape