Protein Ontology Report - prefoldin complexGO:0016272 - http://purl.obolibrary.org/obo/GO_0016272 |
| Ontology Information | ||||
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| PRO ID | GO:0016272 Show OBO stanza | |||
| PRO name | prefoldin complex | |||
| Synonyms |
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| Definition | A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. [GOC:jl, PMID:17384227, PMID:24068951, PMID:9630229] | |||
| PRO Category | ||||
| Parent | GO:0032991 protein-containing complex | |||
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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