| PRO ID |
GO:0097071
Show OBO stanza
|
| PRO name |
interferon regulatory factor complex |
| Synonyms |
| Other: |
EXACT: |
IRF complex |
|
| Definition |
A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
[GOC:cna, PMID:20043992]
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| PRO Category |
|
| Parent |
GO:0032991 protein-containing complex |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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